Guest Lecture by Professor Hedda Wardemann
Professor Hedda Wardemann - Division of B Cell Immunology, German Cancer Research Center, Heidelberg, Germany.
Lecture by Hedda Wardemann
Professor Wardemann will be visiting our center in Oslo, February 7, 2020.
UiO FOCIS CoE - Guest lecture
Time: 14:30 - 15:30, refreshments will be served from 14:15.
Title: The human B cell response to a malaria parasite protein
Single cell Ig gene amplification and sequencing is increasingly used for the molecular assessment of adaptive antigen receptor repertoires. We have developed a platform for the high-throughput analysis of Ig gene repertoires that preserves natural IgH and IgL gene associations and provides full-length Ig gene sequence information for direct gene cloning and the production of recombinant monoclonal antibodies. I will discuss how we use this platform to study the clonal evolution and functional quality of human B cell immune responses after repeated controlled exposure to a complex pathogen, the malaria parasite Plasmodium falciparum.
Find more information about Prof. Wardemann: https://www.dkfz.de/en/b-zell-immunologie/index.php