Guest Lecture by Professor Hedda Wardemann

Professor Hedda Wardemann - Division of B Cell Immunology, German Cancer Research Center, Heidelberg, Germany.

photo hedda wardemann


Lecture by Hedda Wardemann

Professor Wardemann will be visiting our center in Oslo, February 7, 2020.

UiO FOCIS CoE - Guest lecture

Time: 14:30 - 15:30, refreshments will be served from 14:15.

Title: The human B cell response to a malaria parasite protein

Single cell Ig gene amplification and sequencing is increasingly used for the molecular assessment of adaptive antigen receptor repertoires. We have developed a platform for the high-throughput analysis of Ig gene repertoires that preserves natural IgH and IgL gene associations and provides full-length Ig gene sequence information for direct gene cloning and the production of recombinant monoclonal antibodies. I will discuss how we use this platform to study the clonal evolution and functional quality of human B cell immune responses after repeated controlled exposure to a complex pathogen, the malaria parasite Plasmodium falciparum.

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Published Nov. 26, 2019 8:32 AM - Last modified Feb. 4, 2020 7:34 AM