Finn Olav Levy

Bilde av Finn Olav Levy
English version of this page
Telefon +47 22840237
Mobiltelefon +47 47271676
Brukernavn
Besøksadresse Sognsvannsveien 20 Rikshospitalet 0372 Oslo
Postadresse Postboks 1057 Blindern 0316 Oslo

Faglige interesser

Forskning om hjertesvikt, hjertefarmakologi og cellulær signaloverføring

Undervisning

Undervisning i farmakologi for medisinstudenter fra 3. til 12. semester

Bakgrunn

  • Cand. med., Universitetet i Oslo 1987
  • Dr. med., Universitetet i Oslo 1989
  • Autorisasjon som lege 1990
  • Professor i farmakologi fra 2004 

Verv

  • Fagmiljøleder, Avdeling for farmakologi

Samarbeid

Utstrakt nasjonalt og internasjonalt forskningssamarbeid vedr. hjertesvikt, hjertefarmakologi og cellulær signaloverføring

Emneord: Serotonin, Hjertesvikt, Reseptor, G-protein, Farmakologi

Publikasjoner

Se alle arbeider i Cristin

  • Ytrehus, Kirsti; Larsen, Terje; Christensen, Geir Arve; Stensløkken, Kåre-Olav & Levy, Finn Olav (2015). In memory of Guro Valen (1960-2014). Journal of Molecular and Cellular Cardiology. ISSN 0022-2828. 79, s. 254–255. doi: 10.1016/j.yjmcc.2014.11.026.
  • Meier, Silja; Andressen, Kjetil Wessel; Aronsen, Jan Magnus; Sjaastad, Ivar; Skomedal, Tor & Osnes, Jan-Bjørn [Vis alle 9 forfattere av denne artikkelen] (2015). Enhancement of cAMP-mediated inotropic responses by CNP is regulated differently by PDE2 in normal and failing hearts. BMC Pharmacology & Toxicology. ISSN 2050-6511. 16, s. A66–A66. doi: 10.1186/2050-6511-16-S1-A66.
  • Dugstad, K.; Ulsund, Andrea Hembre; Aronsen, Jan Magnus; Sjaastad, Ivar; Zaccolo, Manuela & Levy, Finn Olav [Vis alle 7 forfattere av denne artikkelen] (2014). Unraveling tight spatial regulation of 5-HT4 receptor-mediated inotropic effects using targeted FRET-based cAMP sensors.
  • Meier, Silja; Moltzau, Lise Roman; Aronsen, Jan Magnus; Sjaastad, Ivar; Skomedal, Tor & Osnes, Jan-Bjørn [Vis alle 8 forfattere av denne artikkelen] (2014). Enhancement of B1 - adrenoceptor signaling by CNP through NPR-B and regulation by phosphodiesterases in normal and failing hearts.
  • Levy, Finn Olav (2013). Cardiac PDEs and crosstalk between cAMP and cGMP signalling pathways in the regulation of contractility. Naunyn-Schmiedeberg's Archives of Pharmacology. ISSN 0028-1298. 386(8), s. 665–670. doi: 10.1007/s00210-013-0874-z.
  • Dugstad, Kari Sandanger; Andressen, Kjetil Wessel; Aronsen, Jan Magnus; Sjaastad, Ivar; Zaccolo, Manuela & Levy, Finn Olav (2012). Compartmented production and degradation of cAMP by beta-adrenergic, prostanoid and 5-HT4 receptors in CHF, visualized by FRET-based cAMP sensors.
  • Moltzau, Lise Roman; Aronsen, Jan Magnus; Meier, Silja; Sjaastad, Ivar; Skomedal, Tor & Osnes, Jan-Bjørn [Vis alle 8 forfattere av denne artikkelen] (2012). NPR-A and NPR-B signal in different functional compartments in failing rat left ventricle. Cardiovascular Research (CVR). ISSN 0008-6363. 93, s. S18–S18. doi: 10.1093/cvr/cvr332.
  • Moltzau, Lise Roman; Aronsen, Jan Magnus; Meier, Silja; Nguyen, Cam; Christensen, Geir Arve & Sjaastad, Ivar [Vis alle 10 forfattere av denne artikkelen] (2011). The negative inotropic and positive lusitropic responses to CNP are dependent on SERCA2 activity in failing rat ventricle.
  • Moltzau, Lise Roman; Aronsen, Jan Magnus; Meier, Silja; Nguyen, Cam; Christensen, Geir Arve & Sjaastad, Ivar [Vis alle 10 forfattere av denne artikkelen] (2011). The mechanism of CNP-induced negative inotropic and positive lusitropic responses are dependent on SERCA activity in failing rat ventricle.
  • Melsom, CB; Hussain, Rizwan; Aronsen, Jan Magnus; Sjaastad, Ivar; Osnes, Jan-Bjørn & Skomedal, Tor [Vis alle 8 forfattere av denne artikkelen] (2011). The role of inhibitory G protein upon beta-adrenoceptor-mediated signalling and inotropic responses in normal and failing rat heart left ventricle: Functional evidence of "tonic" Gi activation.
  • Andressen, Kjetil Wessel; Dugstad, KS; Aronsen, Jan Magnus; Sjaastad, Ivar; Zaccolo, Manuela & Levy, Finn Olav (2011). Unraveling tight spatiotemporal regulation of cAMP-mediated inotropic effects using targeted FRET-based cAMP sensors.
  • Meier, Silja; Aronsen, Jan Magnus; Sjaastad, Ivar; Levy, Finn Olav; Skomedal, Tor & Osnes, Jan-Bjørn [Vis alle 7 forfattere av denne artikkelen] (2011). Enhancement of B1-adrenoceptor signaling by C-type natriuretic peptide through natriuretic peptide receptor B in normal and failing hearts: regulation by phosphodiesterases.
  • Meier, Silja; Levy, Finn Olav; Skomedal, Tor; Qvigstad, Eirik & Osnes, Jan-Bjørn (2010). Cardiac tissue hypothyroidism and receptor functions in heart failure.
  • Qvigstad, Eirik; Afzal, Faraz; Aronsen, Jan Magnus; Moltzau, Lise Roman; Sjaastad, Ivar & Skomedal, Tor [Vis alle 8 forfattere av denne artikkelen] (2010). The NO/cyclic GMP signalling pathway differentially affects 5-HT4 - and B1-AR mediated inotropic responses in failing ventricle.
  • Meier, Silja; Aronsen, Jan Magnus; Levy, Finn Olav; Skomedal, Tor; Osnes, Jan-Bjørn & Qvigstad, Eirik (2010). C-type natriuretic peptide signalling through NPR-B enhances the B1-AR signalling both in non-failing and failing rat hearts.
  • Moltzau, Lise Roman; Aronsen, Jan Magnus; Meier, Silja; Nguyen, Hong Cam Thi; Afzal, Faraz & Sjaastad, Ivar [Vis alle 10 forfattere av denne artikkelen] (2010). Compartmentation of the cGMP signal causes differential functional responses after CNP and BNP stimulation in failing myocardium.
  • Larsen, Karl-Otto; Lygren, Birgitte; Sjaastad, Ivar; Krobert, Kurt Allen; Arnkværn, Kristin & Florholmen, Geir [Vis alle 10 forfattere av denne artikkelen] (2009). Mechanisms for cardiac dysfunction in COPD and respiratory failure. Respiratory Medicine. ISSN 0954-6111. 103, s. S6–S7.
  • Afzal, Faraz; Aronsen, Jon magnus; Moltzau, Lise Roman; Sjaastad, Ivar; Levy, Finn Olav & Skomedal, Tor [Vis alle 8 forfattere av denne artikkelen] (2009). Differential regulation of b2-adrenoceptor-mediated responses by PDE3 and PDE4 in failing and non-failing rat myocardium.
  • Krobert, Kurt Allen; Hussain, Rizwan; Afzal, Faraz; Aronsen, Jon magnus; Sjaastad, Ivar & Osnes, Jan-Bjørn [Vis alle 8 forfattere av denne artikkelen] (2009). Inreased Gi activity does not contribute to the reduced beta-adrenergic inotropic effect in failing rat ventricle but Gi acts as a tonic brake on basal adenylyl cyclase activity.
  • Larsen, Karl-Otto; Lygren, Birgitte; Sjaastad, Ivar; Krobert, Kurt Allen; Arnkværn, Kristin & Florholmen, Geir [Vis alle 11 forfattere av denne artikkelen] (2009). Increased circulating IL-18; a possible mechanism for hypoxia-induced cardiac dysfunction.
  • Moltzau, Lise Roman; Aronsen, Jan Magnus; Nguyen, Hong Cam Thi; Sjaastad, Ivar; Afzal, Faraz & Skomedal, Tor [Vis alle 9 forfattere av denne artikkelen] (2008). Phospodiesterases regulating the negative inotropic response of C-type natriuretic peptide in heart failure. Fundamental & Clinical Pharmacology. ISSN 0767-3981. 22, s. 17–17.
  • Levy, Finn Olav (2008). Regulation of the failing cardiac ventricle through 5-HT2A and 5-HT4 receptors: mechanisms and possible therapeutic consequences. Fundamental & Clinical Pharmacology. ISSN 0767-3981. 22, s. 17–17.
  • Levy, Finn Olav (2008). 5-HT4-elicited positive inotropic response is mediated by cAMP and regulated by PDE3 in failing rat and human cardiac ventricle. Fundamental & Clinical Pharmacology. ISSN 0767-3981. 22, s. 131–131.
  • Levy, Finn Olav (2008). Antagonist-mediated down-regulation of 5-HT7 receptors by the atypical antipsychotics clozapine and olanzapine: evidence for functional selectivity. Fundamental & Clinical Pharmacology. ISSN 0767-3981. 22, s. 60–60.
  • Levy, Finn Olav (2008). Role of myocardial 5-HT4 and 5-HT2A receptors in heart failure. Fundamental & Clinical Pharmacology. ISSN 0767-3981. 22, s. 112–112.
  • Kjekshus, John; Edvardsen, Thor; Gullestad, Lars; Koeber, L; Osnes, Jan-Bjørn & Qvigstad, Erik [Vis alle 10 forfattere av denne artikkelen] (2008). The effect of Piboserod a 5-HT4-receptor antagonist on left ventricular function in patients with symptomatic heart failure.
  • Larsen, Karl-Otto; Lygren, Birgitte; Sjaastad, Ivar; Krobert, Kurt Allen; Florholmen, Geir & Arnkværn, Kristin [Vis alle 10 forfattere av denne artikkelen] (2008). Alveolar hypoxia induces cardiac diastolic dysfunction: a role for a reduction in the calcium regulating protein phospholamban induced by IL-18.
  • Larsen, Karl-Otto; Lygren, Birgitte; Sjaastad, Ivar; Krobert, Kurt Allen; Arnkværn, Kristin & Florholmen, Geir [Vis alle 10 forfattere av denne artikkelen] (2008). Mechanisms for cardiac dysfunction in COPD and respiratory failure.
  • Eikemo, Hilde; Nguyen, Hong Cam Thi; Levy, Finn Olav; Skomedal, Tor & Osnes, Jan-Bjørn (2008). Evidence for an unidentified kinase activity phosphorylating myosin light chain-2 in quiescent cardiomyocytes. Journal of Molecular and Cellular Cardiology. ISSN 0022-2828. 44, s. 782–782. doi: 10.1016/j.yjmcc.2008.02.170.
  • Krobert, Kurt Allen; Hussain, Rizwan; Mørk, Halvor Kjeang; Qvigstad, Eirik; Sjaastad, Ivar & Osnes, Jan-Bjørn [Vis alle 8 forfattere av denne artikkelen] (2007). cAMP-dependent inotropic effects are differentially regulated by muscarinic inhibition in failing rat ventricle. Journal of Molecular and Cellular Cardiology. ISSN 0022-2828. 42(6), s. S35–S35.
  • Afzal, Faraz & Levy, Finn Olav (2010). Phosphodiesterases and regulation of contractile function through β-adrenoceptors and 5-HT4 receptors in the failing heart. Unipub forlag.
  • Skomedal, Tor; Osnes, Jan-Bjørn & Levy, Finn Olav (2009). Regulation of myosin light chain 2 phosphorylation in cardiac muscle and its possible role in contractile responses. Universitetet i Oslo.
  • Eikemo, Hilde; Skomedal, Tor; Osnes, Jan-Bjørn & Levy, Finn Olav (2009). Regulation of myosin light chain 2 phosphorylation in cardiac muscle and its possible role in contractile responses. Universitetet i Oslo. ISSN 978-82-8072-348-2.
  • Andressen, Kjetil Wessel & Levy, Finn Olav (2008). The 5-HT₇ serotonin receptor : G protein preassociation and functional selectivity. Unipub forlag. ISSN 978-82-8072-747-3.

Se alle arbeider i Cristin

Publisert 13. apr. 2011 11:41 - Sist endret 26. okt. 2016 14:20