Ingrid Nermoen

• Grønning, Kaja; Sharma, Archana; Mastroianni, Maria Adele; Karlsson, Bo Daniel; Husebye, Eystein Sverre; Løvås, Kristian & Nermoen, Ingrid (2020). Primary adrenal lymphoma as a cause of adrenal insufficiency, a report of two cases. Endocrinology, Diabetes & Metabolism.  ISSN 2398-9238.  2020(1), s 1- 5 . doi: 10.1530/EDM-19-0131 Fulltekst i vitenarkiv.
• Hatlen, Kristine Vaage; Sharma, Archana & Nermoen, Ingrid (2020). Servere ketoacidosis in a patient taking an SLGT2 inhibitorfor diabetes. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  140(12), s 1- 4 . doi: 10.4045/tidsskr.19.0826
• Nermoen, Ingrid & Falhammar, Henrik (2020). Prevalence and characteristics of adrenal tumors and myelolipomas in congenital adrenal hyperplasia: A systematic review and meta-analysis. Endocrine Practice.  ISSN 1530-891X.  26(11), s 1351- 1365 . doi: 10.4158/EP-2020-0058
• Sævik, Åse Bjorvatn; Åkerman, Anna-Karin; Methlie, Paal; Quinkler, Marcus; Jørgensen, Anders Palmstrøm; Høybye, Charlotte; Debowska, Aleksandra; Nedrebø, Bjørn Gunnar; Dahle, Anne Lise; Carlsen, Siri; Tomkowicz, Aneta; Sollid, Stina Therese; Nermoen, Ingrid; Grønning, Kaja; Dahlqvist, Per; Grimnes, Guri; Skov, Jakob; Finnes, Trine Elisabeth; Valland, Susanna Fonneland; Wahlberg, Jeanette; Holte, Synnøve Emblem; Simunkova, Katerina; Kämpe, Olle; Husebye, Eystein Sverre; Bensing, Sophie & Øksnes, Marianne (2020). Residual Corticosteroid Production in Autoimmune Addison Disease. Journal of Clinical Endocrinology and Metabolism.  ISSN 0021-972X.  105(7), s 2430- 2441 . doi: doi:10.1210/clinem/dgaa256 Fulltekst i vitenarkiv. Vis sammendrag

  Design: Two-staged, cross-sectional clinical study in 17 centers (Norway, Sweden, and Germany). Residual glucocorticoid (GC) production was defined as quantifiable serum cortisol and 11-deoxycortisol and residual mineralocorticoid (MC) production as quantifiable serum aldosterone and corticosterone after > 18 hours of medication fasting. Corticosteroids were analyzed by liquid chromatography–tandem mass spectrometry. Clinical variables included frequency of adrenal crises and quality of life. Peak cortisol response was evaluated by a standard 250 µg cosyntropin test. Results: Fifty-eight (30.2%) of 192 patients had residual GC production, more common in men (n = 33; P < 0.002) and in shorter disease duration (median 6 [0-44] vs 13 [0-53] years; P < 0.001). Residual MC production was found in 26 (13.5%) patients and associated with shorter disease duration (median 5.5 [0.5-26.0] vs 13 [0-53] years; P < 0.004), lower fludrocortisone replacement dosage (median 0.075 [0.050-0.120] vs 0.100 [0.028-0.300] mg; P < 0.005), and higher plasma renin concentration (median 179 [22-915] vs 47.5 [0.6-658.0] mU/L; P < 0.001). There was no significant association between residual production and frequency of adrenal crises or quality of life. None had a normal cosyntropin response, but peak cortisol strongly correlated with unstimulated cortisol (r = 0.989; P < 0.001) and plasma adrenocorticotropic hormone (ACTH; r = –0.487; P < 0.001). Conclusion: In established AAD, one-third of the patients still produce GCs even decades after diagnosis. Residual production is more common in men and in patients with shorter disease duration but is not associated with adrenal crises or quality of life. (J Clin Endocrinol Metab 105: 1–12, 2020) Key words: Adrenal failure; adrenal steroids; Autoimmune Addison disease; cortisol; primary adrenal insufficiency; residual function

• Daae, Elisabeth; Feragen, Kristin Judith Billaud; Nermoen, Ingrid & Falhammar, Henrik (2018). Psychological adjustment, quality of life, and self-perceptions of reproductive health in males with congenital adrenal hyperplasia: a systematic review. Endocrine.  ISSN 1355-008X.  62(1), s 3- 13 . doi: 10.1007/s12020-018-1723-0 Fulltekst i vitenarkiv.
• Dahl, Sandra Rinne; Nermoen, Ingrid; Brønstad, Ingeborg; Husebye, Eystein Sverre; Løvås, Kristian & Thorsby, Per Medbøe (2018). Assay of steroids by liquid chromatography-tandem mass spectrometry in monitoring 21-hydroxylase deficiency.. Endocrine Connections.  ISSN 2049-3614.  7(12), s 1542- 1550 . doi: 10.1530/EC-18-0453
• Sævik, Åse Bjorvatn; Åkerman, Anna Karin; Grønning, Kaja; Nermoen, Ingrid; Valland, Susanna Fonneland; Finnes, Trine Elisabeth; Isaksson, Magnus; Dahlqvist, Per; Bergthórsdóttir, Ragnhildur; Ekwall, Olov; Skov, Jakob; Nedrebø, Bjørn Gunnar; Hulting, Anne Lena; Wahlberg, Jeanette; Svartberg, Johan; Höybye, Charlotte; Bleskestad, Inger Hjørdis; Jørgensen, Anders Palmstrøm; Kämpe, Olle; Øksnes, Marianne; Bensing, Sophie & Husebye, Eystein Sverre (2017). Clues for early detection of autoimmune Addison's disease - myths and realities. Journal of Internal Medicine.  ISSN 0954-6820.  283(2), s 190- 199 . doi: 10.1111/joim.12699
• Valderhaug, Tone Gretland; Sharma, Archana; Kravdal, Gunnhild; Rønningen, Reidun & Nermoen, Ingrid (2017). The usage of fasting glucose and glycated hemoglobin for the identification of unknown type 2 diabetes in high risk patients with morbid obesity. Scandinavian Journal of Clinical and Laboratory Investigation.  ISSN 0036-5513.  77(7), s 505- 512 . doi: 10.1080/00365513.2017.1347958
• Brønstad, Ingeborg; Breivik, Lars Ertesvåg; Methlie, Paal; Wolff, Anette Susanne Bøe; Bratland, Eirik; Nermoen, Ingrid; Løvås, Kristian & Husebye, Eystein Sverre (2014). Functional studies of novel CYP21A2 mutations detected in Norwegian patients with congenital adrenal hyperplasia. Endocrine Connections.  ISSN 2049-3614.  15(3), s 67- 74 . doi: 10.1530/EC-14-0032 Fulltekst i vitenarkiv.
• Nermoen, Ingrid; Brønstad, Ingeborg; Fougner, Kristian J; Svartberg, Johan; Øksnes, Marianne; Husebye, Eystein Sverre & Løvås, Kristian (2012). Genetic, anthropometric and metabolic features of adult Norwegian patients with 21-hydroxylase deficiency. European Journal of Endocrinology.  ISSN 0804-4643.  167(4), s 507- 516 . doi: 10.1530/EJE-12-0196
• Nermoen, Ingrid; Rørvik, Jarle; Holmedal, Stein Harald; Hykkerud, Dan L; Fougner, Kristian J; Svartberg, Johan; Husebye, Eystein Sverre & Løvås, Kristian (2011). High frequency of adrenal myelolipomas and testicular adrenal rest tumours in adult Norwegian patients with classical congenital adrenal hyperplasia because of 21-hydroxylase deficiency. Clinical Endocrinology.  ISSN 0300-0664.  75(6), s 753- 759 . doi: 10.1111/j.1365-2265.2011.04151.x
• Nermoen, Ingrid; Husebye, Eystein; Svartberg, Johan & Løvås, K (2010). Subjective health status in men and women with congenital adrenal hyperplasia: a population-based survey in Norway. European Journal of Endocrinology.  ISSN 0804-4643.  163(3), s 453- 459 . doi: 10.1530/EJE-10-0284
• Radtke, Maria Anita; Nermoen, Ingrid; Kollind, Magnus; Skeie, Svein; Sørheim, Jan Inge; Svartberg, Johan; Moen, Torolf; Hals, Ingrid; Dørflinger, Gry Høst & Grill, Valdemar (2010). Six Months of Diazoxide Treatment at Bedtime in Newly Diagnosed Subjects With Type 1 Diabetes Does Not Influence Parameters of beta-Cell Function and Autoimmunity but Improves Glycemic Control. Diabetes Care.  ISSN 0149-5992.  33(3), s 589- 594 . doi: 10.2337/dc09-1436
• Nermoen, Ingrid; Følling, Ivar; Vegge, Kjetil; Larmo, Arne; Nedrebø, Bjørn Gunnar; Husebye, Eystein Sverre & Løvås, Kristian (2009). Two adults with adrenal myelolipoma and 21-hydroxylase deficiency. Clinical Medicine : Case Reports.  ISSN 1178-6450. . doi: 10.1155/2009/916891
• Jensen, TK; Jørgensen, Niels; Punab, M.; Haugen, TB; Suominen, J; Zilaitiene, B; Horte, A; Andersen, AG; Carlsen, Elisabeth; Magnus, Øystein; Matulevicius, V; Nermoen, Ingrid; Vierula, M; Keiding, N; Toppari, J & Skakkebaek, NE (2004). Association of in utero exposure to maternal smoking with reduced semen quality and testis size in adulthood: a cross-sectional study of 1,770 young men from the general population in five European countries. American Journal of Epidemiology.  ISSN 0002-9262.  159(1), s 49- 58
• Nermoen, Ingrid; Foss, Aksel; Holte, Harald; Mathisen, Øystein; Brekke, Inge Bjørn; Line, Pål Dag & Bergan, Anstein Bjørnar (2004). [Surgical treatment of hormone-producing adrenocortical carcinoma with liver metastases]. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  124(33), s 3061- 3063
• Jørgensen, Niels; Carlsen, Elisabeth; Nermoen, Ingrid; Punab, M.; Suominen, J.; Andersen, AG; Andersson, AM; Haugen, TB; Horte, A; Jensen, TK; Magnus, Øystein; Petersen, J H.; Vierula, M; Toppari, J & Skakkebaek, NE (2002). East-West gradient in semen quality in the Nordic-Baltic area: a study of men from the general population in Denmark, Norway, Estonia and Finland. Human Reproduction.  ISSN 0268-1161.  17(8), s 2199- 2208
• Carlsen, Elisabeth; Andersen, AG; Jørgensen, Niels; Magnus, Øystein; matulevicuus, v; buchreitz, l; Nermoen, Ingrid; petersen, jh; Punab, M; Suominen, J; Zilaitiene, B & Giwercman, Aleksander (2000). Inter-observer variation in the results of the clinical andrological examination including estimation of testicular size. International Journal of Andrology.  ISSN 0105-6263.  23(4), s 248- 253
• Nermoen, Ingrid; Jorde, Rolf; Sager, Georg; Sundsfjord, J. & Birkeland, Kari (1998). Effects of exercise on hypoglycaemic responses in insulin-dependent diabetes mellitus. Diabetes & Metabolism.  ISSN 1262-3636.  24(2), s 131- 136

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• Følling, Ivar; Lima, Kari & Nermoen, Ingrid (2017). Forstyrrelse i salt-og vannhusholdningen og endokrin hypertensjon, I:  Indremedisin I & II.  Forlag Vett & Viten.  ISBN 9788241207402.  24.  s 295 - 305
• Nermoen, Ingrid; Husebye, Eystein Sverre; Myhre, Anne Margrethe & Løvås, Kristian (2017). Klassisk medfødt binyrebarkhyperplasi. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  137(7), s 540- 543 . doi: 10.4045/tidsskr.16.0376
• Nermoen, Ingrid (2013). Congenital Adrenal Hyperplasia in Adults: Epidemiological, Genetic, Clinical and Endocrine Features of CYP21A2 Deficiency in Norway. Series of dissertations submitted to the Faculty of Medicine, University of Oslo. ?.
• Radtke, Maria Anita; Nermoen, Ingrid; Kollind, Magnus; Skeie, Svein; Sørheim, Jan Inge; Svartberg, Johan & Grill, Valdemar (2009). A 6-month treatment with diazoxide at bedtime in newly diagnosed subjects with type 1 diabetes does not influence measured parameters of beta cell function, but improves glycaemic control. Diabetologia.  ISSN 0012-186X.  52, s S385- S385

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