Manoj Amrutkar

Bilde av Manoj Amrutkar
English version of this page
Rom A2.3064
Besøksadresse Avdeling for farmakologi OUS Rikshospitalet
Postadresse OUS, Rikshospitalet Postboks 4950 Nydalen 0424 Oslo
Andre tilknytninger Det medisinske fakultet (Student)


  • Amrutkar, Manoj; Larsen, Emma Kristine; Aasrum, Monica; Finstadsveen, Anette Vefferstad; Andresen, Per Arne; Verbeke, Caroline Sophie & Gladhaug, Ivar Prydz (2020). Establishment and Characterization of Paired Primary Cultures of Human Pancreatic Cancer Cells and Stellate Cells Derived from the Same Tumor. Cells.  ISSN 2073-4409.  9:227(1), s 1- 18 . doi: 10.3390/cells9010227 Fulltekst i vitenarkiv.
  • Amrutkar, Manoj; Aasrum, Monica; Verbeke, Caroline Sophie & Gladhaug, Ivar Prydz (2019). Secretion of fibronectin by human pancreatic stellate cells promotes chemoresistance to gemcitabine in pancreatic cancer cells. BMC Cancer.  ISSN 1471-2407.  19(596) . doi: 10.1186/s12885-019-5803-1 Fulltekst i vitenarkiv.
  • Cansby, Emmelie; Kulkarni, Nagaraj M; Magnusson, Elin; Kurhe, Yeshwant; Amrutkar, Manoj; Nerstedt, Annika; Ståhlman, Marcus; Sihlbom, Carina; Marschall, Hanns-Ulrich; Borén, Jan; Blüher, Matthias & Mahlapuu, Margit (2019). Protein Kinase MST3 Modulates Lipid Homeostasis in Hepatocytes and Correlates With Nonalcoholic Steatohepatitis in Humans. The FASEB Journal.  ISSN 0892-6638.  33(9), s 9974- 9989 . doi: 10.1096/fj.201900356RR
  • Cansby, Emmelie; Nunez-duran, Esther; Magnusson, Elin; Amrutkar, Manoj; Booten, Sheri L.; Kulkarni, Nagaraj M; Svensson, L. Thomas; Borén, Jan; Marschall, Hanns-Ulrich; Aghajan, Mariam & Mahlapuu, Margit (2019). Targeted Delivery of Stk25 Antisense Oligonucleotides to Hepatocytes Protects Mice Against Nonalcoholic Fatty Liver Disease. Cellular and Molecular Gastroenterology and Hepatology (CMGH).  ISSN 2352-345X.  7(3), s 597- 618 . doi: 10.1016/j.jcmgh.2018.12.004 Fulltekst i vitenarkiv.
  • Lenggenhager, Daniela; Amrutkar, Manoj; Santha, Petra; Aasrum, Monica; Löhr, Johannes-Matthias; Gladhaug, Ivar Prydz & Verbeke, Caroline Sophie (2019). Commonly Used Pancreatic Stellate Cell Cultures Differ Phenotypically and in Their Interactions With Pancreatic Cancer Cells. Cells.  ISSN 2073-4409.  8:E23(1), s 1- 18 . doi: 10.3390/cells8010023 Fulltekst i vitenarkiv.
  • Cansby, Emmelie; Magnusson, Elin; Nunez-duran, Esther; Amrutkar, Manoj; Pedrelli, Matteo; Parini, Paolo; Hoffmann, Jenny; Ståhlman, Marcus; Howell, Brian w.; Marschall, Hanns-Ulrich; Borén, Jan & Mahlapuu, Margit (2018). STK25 Regulates Cardiovascular Disease Progression in a Mouse Model of Hypercholesterolemia. Arteriosclerosis, Thrombosis and Vascular Biology.  ISSN 1079-5642.  38(8) . doi: 10.1161/ATVBAHA.118.311241
  • Sutt, Silva; Cansby, Emmelie; Paul, Alexandra; Amrutkar, Manoj; Nunez-duran, Esther; Kulkarni, Nagaraj M; Ståhlman, Marcus; Boren, Jan; Laurencikiene, Jurga; Howell, Brian w.; Enerbäck, Sven & Mahlapuu, Margit (2018). STK25 regulates oxidative capacity and metabolic efficiency in adipose tissue. Journal of Endocrinology.  ISSN 0022-0795.  238(3), s 187- 202 . doi: 10.1530/JOE-18-0182 Fulltekst i vitenarkiv.
  • Amrutkar, Manoj & Gladhaug, Ivar Prydz (2017). Pancreatic cancer chemoresistance to gemcitabine. Cancers.  ISSN 2072-6694.  9(11:157), s 1- 23 . doi: 10.3390/cancers9110157

Se alle arbeider i Cristin

  • Chursa, Urszula; Nunez-duran, Esther; Cansby, Emmelie; Amrutkar, Manoj; Sutt, Silva; Ståhlman, Marcus; Olsson, Britt-marie; Borén, Jan; Johansson, Maria e.; Bäckhed, Fredrik; Johansson, Bengt r.; Sihlbom, Carina & Mahlapuu, Margit (2017). Overexpression of protein kinase STK25 in mice exacerbates ectopic lipid accumulation, mitochondrial dysfunction and insulin resistance in skeletal muscle. Diabetologia.  ISSN 0012-186X.  60(3), s 553- 567 . doi: 10.1007/s00125-016-4171-5
  • Nunez-duran, Esther; Aghajan, Mariam; Amrutkar, Manoj; Sutt, Silva; Cansby, Emmelie; Booten, Sheri l.; Watt, Andrew; Ståhlman, Marcus; Stefan, Norbert; Haring, Hans-ulrich; Staiger, Harald; Borén, Jan; Marschall, Hanns-Ulrich & Mahlapuu, Margit (2017). Serine/Threonine Protein Kinase 25 Antisense Oligonucleotide Treatment Reverses Glucose Intolerance, Insulin Resistance, and Nonalcoholic Fatty Liver Disease in Mice. Hepatology communications..  ISSN 2471-254X.  2(1), s 69- 83 . doi: 10.1002/hep4.1128
  • Amrutkar, Manoj; Chursa, Urszula; Kern, Matthias; Nunez-duran, Esther; Ståhlman, Marcus; Sutt, Silva; Borén, Jan; Johansson, Bengt r.; Marschall, Hanns-Ulrich; Blüher, Matthias & Mahlapuu, Margit (2016). STK25 is a critical determinant in nonalcoholic steatohepatitis. The FASEB Journal.  ISSN 0892-6638.  30(10), s 3628- 3643 . doi: 10.1096/fj.201600562R
  • Amrutkar, Manoj; Kern, Matthias; Nunez-duran, Esther; Ståhlman, Marcus; Cansby, Emmelie; Chursa, Urszula; Stenfeldt, Elin; Borén, Jan; Blüher, Matthias & Mahlapuu, Margit (2016). Protein kinase STK25 controls lipid partitioning in hepatocytes and correlates with liver fat content in humans. Diabetologia.  ISSN 0012-186X.  59, s 341- 353 . doi: 10.1007/s00125-015-3801-7
  • Amrutkar, Manoj; Cansby, Emmelie; Chursa, Urszula; Nunez-duran, Esther; Chanclón, Belén; Ståhlman, Marcus; Friden, Vincent; Mannerås-holm, Louise; Wickman, Anna; Smith, Ulf; Bäckhed, Fredrik; Borén, Jan; Howell, Brian w. & Mahlapuu, Margit (2015). Genetic Disruption of Protein Kinase STK25 Ameliorates Metabolic Defects in a Diet-Induced Type 2 Diabetes Model. Diabetes.  ISSN 0012-1797.  64, s 2791- 2804 . doi: 10.2337/db15-0060
  • Amrutkar, Manoj; Cansby, Emmelie; Nunez-duran, Esther; Pirazzi, Carlo; Ståhlman, Marcus; Stenfeldt, Elin; Smith, Ulf; Borén, Jan & Mahlapuu, Margit (2015). Protein kinase STK25 regulates hepatic lipid partitioning and progression of liver steatosis and NASH. The FASEB Journal.  ISSN 0892-6638.  29(4), s 1564- 1576 . doi: 10.1096/fj.14-264937
  • Cansby, Emmelie; Nerstedt, Annika; Amrutkar, Manoj; Nunez-duran, Esther; Smith, Ulf & Mahlapuu, Margit (2014). Partial hepatic resistance to IL-6-induced inflammation develops in type 2 diabetic mice, while the anti-inflammatory effect of AMPK is maintained. Molecular and Cellular Endocrinology.  ISSN 0303-7207.  393, s 143- 151 . doi: 10.1016/j.mce.2014.06.014
  • Cansby, Emmelie; Amrutkar, Manoj; Mannerås-holm, Louise; Nerstedt, Annika; Reyahi, Azadeh; Stenfeldt, Elin; Booten, Sheri l.; Carlsson, Peter; Smith, Ulf; Zierath, Juleen r. & Mahlapuu, Margit (2013). Increased expression of STK25 leads to impaired glucose utilization and insulin sensitivity in mice challenged with a high-fat diet. The FASEB Journal.  ISSN 0892-6638.  27(9), s 3660- 3671 . doi: 10.1096/fj.13-228494
  • Nerstedt, Annika; Cansby, Emmelie; Amrutkar, Manoj; Smith, Ulf & Mahlapuu, Margit (2013). Pharmacological activation of AMPK suppresses inflammatory response evoked by IL-6 signalling in mouse liver and in human hepatocytes. Molecular and Cellular Endocrinology.  ISSN 0303-7207.  375, s 68- 78 . doi: 10.1016/j.mce.2013.05.013

Se alle arbeider i Cristin

Publisert 19. jan. 2017 10:08 - Sist endret 31. jan. 2017 10:30