Øistein Hovde

• Mohammed, Ahmed Kedir; Yildirim Yayilgan, Sule; Farup, Ivar; Pedersen, Marius & Hovde, Øistein (2019). StreoScenNet: Surgical stereo robotic scene segmentation. Progress in Biomedical Optics and Imaging.  ISSN 1605-7422.  1095:109510P1 . doi: 10.1117/12.2512518
• Frigstad, Svein Oskar; Høivik, Marte Lie; Jahnsen, Jørgen; Småstuen, Milada Cvancarova; Grimstad, Tore; Berset, Ingrid Prytz; Huppertz-Hauss, Gert; Hovde, Øistein; Bernklev, Tomm; Moum, Bjørn & Jelsness-Jørgensen, Lars-Petter (2018). Fatigue is not associated with vitamin D deficiency in inflammatory bowel disease patients. World Journal of Gastroenterology.  ISSN 1007-9327.  24(29), s 3293- 3301 . doi: 10.3748/wjg.v24.i29.3293
• Mohammed, Ahmed Kedir; Farup, Ivar; Pedersen, Marius; Hovde, Øistein & Yildirim Yayilgan, Sule (2018). Stochastic Capsule Endoscopy Image Enhancement. Journal of Imaging.  ISSN 2313-433X.  4(6) . doi: 10.3390/jimaging4060075 Fulltekst i vitenarkiv.
• Mohammed, Ahmed Kedir; Farup, Ivar; Yildirim, Sule; Pedersen, Marius & Hovde, Øistein (2018). Variational approach for capsule video frame interpolation. EURASIP Journal on Image and Video Processing.  ISSN 1687-5176.  2018:30, s 1- 13 . doi: 10.1186/s13640-018-0267-9 Fulltekst i vitenarkiv.
• Mohammed, Ahmed Kedir; Pedersen, Marius; Hovde, Øistein & Yildirim Yayilgan, Sule (2018). Deep-STRESS Capsule Video Endoscopy Image Enhancement. Final program and proceedings (Color and Imaging Conference).  ISSN 2166-9635.  s 247- 252 . doi: 10.2352/ISSN.2169-2629.2018.26.247
• Frigstad, Svein Oskar; Høivik, Marte; Jahnsen, Jørgen; Dahl, Sandra Rinne; Småstuen, Milada C; Grimstad, Tore; Berset, Ingrid Prytz; Huppertz-Hauss, Gert; Hovde, Øistein; Torp, Roald; Bernklev, Tomm; Moum, Bjørn & Jelsness-Jørgensen, Lars-Petter (2017). Vitamin D deficiency in inflammatory bowel disease: Prevalence and predictors in a Norwegian outpatient population. Scandinavian Journal of Gastroenterology.  ISSN 0036-5521.  52(1), s 100- 106 . doi: 10.1080/00365521.2016.1233577 Vis sammendrag

  Background and aim: Vitamin D deficiency is common in inflammatory bowel disease (IBD). The aims of the present study were to determine the prevalence of vitamin D deficiency and to identify clinical and epidemiological variables associated with vitamin D deficiency in an outpatient population with IBD. Methods: Participants were recruited from nine hospitals in the southeastern and western regions of Norway as part of an observational, multicentre study from March 2013 to April 2014. Clinical and epidemiological data were collected by interview and from medical records. All analyses of serum 25-hydroxyvitamin D (25-OH-D) were performed in the same laboratory. Results: In total, 49% (200/408) of the patients had a 25-OH-D concentration <50 nmol/L, including 53% (122/230) of the Crohn’s disease (CD) patients and 44% (78/178) of the ulcerative colitis (UC) patients. In CD patients, disease activity, measured as the HBI, was inversely associated with vitamin D deficiency. No such association was observed with the Simple Clinical Colitis Activity Index (SCCAI) scores in UC, but in UC patients, vitamin D deficiency was associated with elevated faecal calprotectin >100 mg/kg. In patients with CD, there were significantly more relapses during the previous year in patients with vitamin D deficiency. Conclusions: Vitamin D deficiency was common, especially in CD, and was associated with increased disease activity, a relapsing disease course and higher inflammatory activity.

• Huppertz-Hauss, Gert; Høivik, Marte; Jelsness-Jørgensen, Lars-Petter; Opheim, Randi; Henriksen, Magne; Høie, Ole Ingebreth; Hovde, Øistein; Kempski-Monstad, Iril Lovise; Solberg, Inger Camilla; Jahnsen, Jørgen; Hoff, Geir; Moum, Bjørn & Bernklev, Tomm (2017). Fatigue in a population-based cohort of patients with inflammatory bowel disease 20 years after diagnosis: The IBSEN study. Scandinavian Journal of Gastroenterology.  ISSN 0036-5521.  52(3), s 351- 358 . doi: 10.1080/00365521.2016.1256425
• Mohammed, Ahmed Kedir; Yildirim, Sule; Pedersen, Marius; Hovde, Øistein & Alaya Cheikh, Faouzi (2017). Sparse coded handcrafted and deep features for colon capsule video summarization. Computer-Based Medical Systems.  ISSN 1063-7125.  2017-June, s 728- 733 . doi: 10.1109/CBMS.2017.13 Fulltekst i vitenarkiv.
• Mohammed, Ahmed Kedir; Yildirim, Sule; Pedersen, Marius; Hovde, Øistein & Alaya Cheikh, Faouzi (2017). Sparse coded handcrafted and deep features for colon capsule video summarization, In  Computer-Based Medical Systems (CBMS), 2017 IEEE 30th International Symposium on.  IEEE.  ISBN 978-1-5386-1710-6.  Chapter.  s 728 - 733
• Rukundo, Olivier; Pedersen, Marius & Hovde, Øistein (2017). Advanced Image Enhancement Method for Distant Vessels and Structures in Capsule Endoscopy. Computational & Mathematical Methods in Medicine.  ISSN 1748-670X.  2017, s 1- 13 . doi: 10.1155/2017/9813165 Fulltekst i vitenarkiv. Vis sammendrag

  This paper proposes an advanced method for contrast enhancement of capsule endoscopic images, with the main objective to obtain sufficient information about the vessels and structures in more distant (or darker) parts of capsule endoscopic images. The proposed method (PM) combines two algorithms for the enhancement of darker and brighter areas of capsule endoscopic images, respectively. The half-unit weighted-bilinear algorithm (HWB) proposed in our previous work is used to enhance darker areas according to the darker map content of its HSV’s component . Enhancement of brighter areas is achieved thanks to the novel threshold weighted-bilinear algorithm (TWB) developed to avoid overexposure and enlargement of specular highlight spots while preserving the hue, in such areas. The TWB performs enhancement operations following a gradual increment of the brightness of the brighter map content of its HSV’s component . In other words, the TWB decreases its averaged weights as the intensity content of the component increases. Extensive experimental demonstrations were conducted, and, based on evaluation of the reference and PM enhanced images, a gastroenterologist (Ø.H.) concluded that the PM enhanced images were the best ones based on the information about the vessels, contrast in the images, and the view or visibility of the structures in more distant parts of the capsule endoscopy images.

• Wåhlberg, Henrik; Valle, Per Christian; Malm, Siri; Hovde, Øistein & Broderstad, Ann Ragnhild (2017). The effect of referral templates on out-patient quality of care in a hospital setting: A cluster randomized controlled trial. BMC Health Services Research.  ISSN 1472-6963.  17:177, s 1- 13 . doi: 10.1186/s12913-017-2127-1 Fulltekst i vitenarkiv. Vis sammendrag

  Background The assessment of quality of care is an integral part of modern medicine. The referral represents the handing over of care from the general practitioner to the specialist. This study aimed to assess whether an improved referral could lead to improved quality of care. Methods A cluster randomized trial with the general practitioner surgery as the clustering unit was performed. Fourteen surgeries in the area surrounding the University Hospital of North Norway Harstad were randomized stratified by town versus countryside location. The intervention consisted of implementing referral templates for new referrals in four clinical areas: dyspepsia; suspected colorectal cancer; chest pain; and confirmed or suspected chronic obstructive pulmonary disease. The control group followed standard referral practice. Quality of treatment pathway as assessed by newly developed quality indicators was used as main outcome. Secondary outcomes included subjective quality assessment, positive predictive value of referral and adequacy of prioritization. Assessment of outcomes was done at the individual level. The patients, hospital doctors and outcome assessors were blinded to the intervention status. Results A total of 500 patients were included, with 281 in the intervention and 219 in the control arm. From the multilevel regression model the effect of the intervention on the quality indicator score was insignificant at 1.80% (95% CI, −1.46 to 5.06, p = 0.280). No significant differences between the intervention and the control groups were seen in the secondary outcomes. Active use of the referral intervention was low, estimated at approximately 50%. There was also wide variation in outcome scoring between the different assessors. Conclusions In this study no measurable effect on quality of care or prioritization was revealed after implementation of referral templates at the general practitioner/hospital interface. The results were hindered by a limited uptake of the intervention at GP surgeries and inconsistencies in outcome assessment.

• Eskeland, Sigrun Losada; Brunborg, Cathrine; Seip, Birgitte Karen Berggreen; Wiencke, Kristine; Hovde, Øistein; Owen, Tanja; Skogestad, Erik; Huppertz-Hauss, Gert; Halvorsen, Fred-Arne; Garborg, Kjetil Kjeldstad; Aabakken, Lars & de Lange, Thomas (2016). First quality score for referral letters in gastroenterology—a validation study. BMJ Open.  ISSN 2044-6055.  6(10) . doi: 10.1136/bmjopen-2016-012835 Fulltekst i vitenarkiv. Vis sammendrag

  Abstract Objective To create and validate an objective and reliable score to assess referral quality in gastroenterology. Design An observational multicentre study. Setting and participants 25 gastroenterologists participated in selecting variables for a Thirty Point Score (TPS) for quality assessment of referrals to gastroenterology specialist healthcare for 9 common indications. From May to September 2014, 7 hospitals from the South-Eastern Norway Regional Health Authority participated in collecting and scoring 327 referrals to a gastroenterologist. Main outcome measure Correlation between the TPS and a visual analogue scale (VAS) for referral quality. Results The 327 referrals had an average TPS of 13.2 (range 1–25) and an average VAS of 4.7 (range 0.2–9.5). The reliability of the score was excellent, with an intra-rater intraclass correlation coefficient (ICC) of 0.87 and inter-rater ICC of 0.91. The overall correlation between the TPS and the VAS was moderate (r=0.42), and ranged from fair to substantial for the various indications. Mean agreement was good (ICC=0.47, 95% CI (0.34 to 0.57)), ranging from poor to good. Conclusions The TPS is reliable, objective and shows good agreement with the subjective VAS. The score may be a useful tool for assessing referral quality in gastroenterology, particularly important when evaluating the effect of interventions to improve referral quality.

• Hovde, Øistein; Høivik, Marte Lie; Henriksen, Magne; Solberg, Inger Camilla; Småstuen, Milada Cvancarova & Moum, Bjørn A (2016). Malignancies in Patients with Inflammatory Bowel Disease: Results from 20 Years of Follow-up in the IBSEN Study. Journal of Crohn's and colitis.  ISSN 1873-9946. . doi: 10.1093/ecco-jcc/jjw193
• Hovde, Øistein; Småstuen, Milada C; Høivik, Marte; Bernklev, Tomm; Huppertz-Hauss, Gert; Høie, Ole Ingebreth; Jahnsen, Jørgen; Stray, Njaal; Henriksen, Magne; Solberg, Inger Camilla & Moum, Bjørn (2016). Mortality and Causes of Death in Ulcerative Colitis: Results from 20 Years of Follow-up in the IBSEN Study. Inflammatory Bowel Diseases.  ISSN 1078-0998.  22(1), s 141- 145 . doi: 10.1097/MIB.0000000000000582
• Jelsness-Jørgensen, Lars-Petter; Bernklev, Tomm; Hovde, Øistein; Berset, Ingrid Prytz; Huppertz-Hauss, Gert; Moum, Bjørn & Høivik, Marte (2016). Patients’ perceptions of quality of care and follow-up in inflammatory bowel disease. Scandinavian Journal of Gastroenterology.  ISSN 0036-5521.  51(4), s 434- 441 . doi: 10.3109/00365521.2015.1102319
• Jelsness-Jørgensen, Lars-Petter; Moum, Bjørn; Grimstad, Tore; Jahnsen, Jørgen; Opheim, Randi; Berset, Ingrid Prytz; Hovde, Øistein; Torp, Roald; Frigstad, Svein Oskar; Huppertz-Hauss, Gert & Bernklev, Tomm (2016). Validity, reliability, and responsiveness of the brief pain inventory in inflammatory bowel disease. Canadian journal of gastroenterology & hepatology.  ISSN 2291-2789.  2016:5624261 . doi: 10.1155/2016/5624261
• Kapica, Aida; Hov, Johannes Espolin Roksund; Borthne, Arne Sigmund; Gleditsch, Jostein; Johannesen, Glenn; Tveit, Knut; Viktil, Ellen; Henriksen, Magne; Hovde, Øistein; Huppertz-Hauss, Gert; Høie, Ole Ingebreth; Høivik, Marte; Kempski-Monstad, Iril Lovise; Solberg, Inger Camilla; Jahnsen, Jørgen; Karlsen, Tom Hemming; Moum, Bjørn; Vatn, Morten H & Negard, Anne (2016). Prevalence of Sclerosing Cholangitis Detected by Magnetic Resonance Cholangiography in Patients With Long-term Inflammatory Bowel Disease. Gastroenterology.  ISSN 0016-5085.  151(4), s 660- 669 . doi: 10.1053/j.gastro.2016.06.021
• Wanderås, Magnus; Moum, Bjørn; Høivik, Marte Lie & Hovde, Øistein (2016). Predictive factors for a severe clinical course in ulcerative colitis: Results from population-based studies. World journal of gastrointestinal pharmacology and therapeutics.  ISSN 2150-5349.  7(2), s 235- 241 . doi: 10.4292/WJGPT.v7.i2.235
• Hovde, Øistein; Huppertz-Hauss, Gert; Høivik, Marte & Moum, Bjørn (2014). Clinical course, treatment strategies, social and economic impact of Ulcerative Colitis: An overview. Austin Journal of Gastroenterology.  ISSN 2381-9219.  1(4), s 1- 9 . doi: id1017
• Hovde, Øistein; Kempski-Monstad, Iril Lovise; Småstuen, Milada Cvancarova; Solberg, Inger Camilla; Henriksen, Magne; Jahnsen, Jørgen; Stray, Njaal & Moum, Bjørn (2014). Mortality and causes of death in Crohn's disease: Results from 20 years of follow-up in the IBSEN study. Gut.  ISSN 0017-5749.  63(5), s 771- 775 . doi: 10.1136/gutjnl-2013-304766
• Kempski-Monstad, Iril Lovise; Hovde, Øistein; Solberg, Inger Camilla & Moum, Bjørn (2014). Clinical course and prognosis in ulcerative colitis: Results from population-based and observational studies. Annals of gastroenterology : quarterly publication of the Hellenic Society of Gastroenterology..  ISSN 1108-7471.  27(2), s 95- 104 Vis sammendrag

  The clinical course of ulcerative colitis (UC) may range from a quiescent course with prolonged periods of remission to fulminant disease requiring intensive medical treatment or surgery. Disease outcome is often determined by relapse rates, the development of colorectal cancer (CRC) and mortality rates. Early patient classification, identifying those with a high risk of developing complicated disease, is essential for choosing appropriate treatment. This paper reviews the clinical outcomes of UC patients as reported in population-based and observational studies representative of the whole patient population. Extensive colitis, a high level of systemic symptoms and young age at diagnosis are factors associated with a high risk of colectomy. Patients with distal disease who progress to extensive colitis seem to be a subgroup with an especially high risk of colectomy. Some prognostic factors of severe disease have been identified which could be used to optimize treatment and possibly reduce future complications. The overall risk of CRC and mortality was not significantly different from that of the background population. These results may have implications for follow-up strategies, especially regarding endoscopic surveillance of UC patients.

• Moum, Bjørn; Hovde, Øistein & Høivik, Marte (2014). What have we learnt about the role of the environment and natural course of IBD in the new millennium? 20-year follow-up of the IBSEN cohort. Digestive Diseases.  ISSN 0257-2753.  32, s 2- 9 . doi: 10.1159/000367818 Vis sammendrag

  The incidence and prevalence of IBD, both Crohn's disease (CD) and ulcerative colitis (UC), have increased in recent years, especially in industrialized countries. Still, the etiology of IBD remains largely unknown. Most research on IBD before the 1990s was conducted on selected patient populations. Selected patient populations are likely to introduce important bias and limit the interpretation and generalizability. The inclusion of both incident and prevalent cases or the inclusion of incident cases over long periods of time (decades) might also introduce bias due to changes in treatment regimens and socioeconomic factors over timer (time-trend bias). Consequently, the choice of a well-characterized population-based inception cohort provides the best opportunity to describe the natural course of a disease. The IBSEN (Inflammatory Bowel Disease in South-Eastern Norway) study followed a large population-based cohort of newly diagnosed IBD patients for 20 years and has contributed significantly to the knowledge of the natural course of IBD.

• Hovde, Øistein; Lie, Øyvind Haugen; Johansson, Per A; Stubhaug, Øystein; Johnson, Egil; Hofstad, Bjørn & Hauge, Truls (2013). Iatrogenic esophago-tracheal fistula: Challenges in diagnosis and management. World Journal of Gastroenterology.  ISSN 1007-9327.  19(4), s 594- 596 . doi: 10.3748/wjg.v19.i4.594
• Hovde, Øistein & Moum, Bjørn (2012). Epidemiology and clinical course of Crohn's disease: Results from observational studies. World Journal of Gastroenterology.  ISSN 1007-9327.  18(15), s 1723- 1731 . doi: 10.3748/wjg.v18.i15.1723
• Larssen, Lene; Medhus, Asle Wilhelm; Kørner, Hartwig; Glomsaker, Tom Birger; Søberg, Taran; Gleditsch, Dagfinn; Hovde, Øistein; Tholfsen, Jan Karl; Skreden, Knut; Nesbakken, Arild & Hauge, Truls (2012). Long-term outcome of palliative treatment with self-expanding metal stents for malignant obstructions of the GI tract. Scandinavian Journal of Gastroenterology.  ISSN 0036-5521.  47(12), s 1505- 1514 . doi: 10.3109/00365521.2012.711854
• Larssen, Lene; Medhus, Asle Wilhelm; Hjermstad, Marianne Jensen; Kørner, Hartwig; Glomsaker, Tom; Søberg, Taran; Gleditsch, Dagfinn; Hovde, Øistein; Nesbakken, Arild; Tholfsen, Jan Karl; Skreden, Knut & Hauge, Truls (2011). Patient-reported outcomes in palliative gastrointestinal stenting: a Norwegian multicenter study. Surgical Endoscopy.  ISSN 0930-2794.  25(10), s 3162- 3169 . doi: 10.1007/s00464-011-1680-7

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• Mohammed, Ahmed Kedir; Yildirim Yayilgan, Sule; Farup, Ivar; Pedersen, Marius & Hovde, Øistein (2018). Y-Net: A deep convolutional neural network to polyp detection.
• Opheim, Randi; Bernklev, Tomm; Jahnsen, Jørgen; Grimstad, Tore; Hovde, Øistein; Berset, Ingrid Prytz; Frigstad, Svein Oskar & Jelsness-Jørgensen, Lars-Petter (2018). Chronic fatigue in patients with inflammatory bowel disease is associated with lower health–related quality of life, low self-esteem, increased anxiety and depression.
• Frigstad, Svein Oskar; Bernklev, Tomm; Dahl, Sandra Rinne; Hovde, Øistein; Jahnsen, Jørgen; Grimstad, Tore; Berset, Ingrid Prytz; Moum, Bjørn; Huppertz-Hauss, Gert & Jelsness-Jørgensen, Lars-Petter (2017). Vitamin D deficiency is not associated with chronic fatigue in inflammatory bowel disease.
• Frigstad, Svein Oskar; Høivik, Marte Lie; Jahnsen, Jørgen; Dahl, Sandra Rinne; Cvancarova, Milada; Grimstad, Tore; Berset, Ingrid Prytz; Huppertz-Hauss, Gert; Hovde, Øistein; Torp, Roald; Bernklev, Tomm; Moum, Bjørn & Jelsness-Jørgensen, Lars-Petter (2017). Vitamin D deficiency is not associated with depression in IBD patients. Journal of Crohn's and colitis.  ISSN 1873-9946.  11, s 444- 445 . doi: 10.1093/ecco-jcc/jjx002.834
• Frigstad, Svein Oskar; Høivik, Marte Lie; Jahnsen, Jørgen; Småstuen, Milada C; Grimstad, Tore; Berset, Ingrid Prytz; Huppertz-Hauss, Gert; Hovde, Øistein; Torp, Roald; Bernklev, Tomm; Moum, Bjørn & Jelsness-Jørgensen, Lars-Petter (2017). Fatigue is not Associated with Vitamin D Deficiency in IBD Patients. Gastroenterology.  ISSN 0016-5085.  152(5), s S945 . doi: 10.1016/S0016-5085(17)33218-3
• Frigstad, Svein Oskar; Høivik, Marte Lie; Moum, Bjørn; Dahl, Sandra Rinne; Jahnsen, Jørgen; Småstuen, Milada Cvancarova; Grimstad, Tore; Berset, Ingrid Prytz; Torp, Roald; Hovde, Øistein; Bernklev, Tomm & Jelsness-Jørgensen, Lars-Petter (2017). Vitamin D deficiency is not associated with depression in IBD patients.
• Frigstad, Svein Oskar; Høivik, Marte Lie; Småstuen, Milada C; Jahnsen, Jørgen; Dahl, Sandra Rinne; Berset, Ingrid Prytz; Huppertz-Hauss, Gert; Hovde, Øistein; Grimstad, Tore; Torp, Roald; Bernklev, Tomm; Moum, Bjørn & Jelsness-Jørgensen, Lars-Petter (2017). Fatigue er ikke assosiert med vitamin D mangel hos IBD pasienter.
• Hovde, Øistein & Skotte, Kjetil (2017). Menn med ulcerøs colitt dør ikke oftere av kreft. Forskning.no.  ISSN 1891-635X.
• Hovde, Øistein (2016). Clinical outcome of inflammatory bowel disease With special emphasis on mortality and cancer Development. The IBSEN study.
• Jelsness-Jørgensen, Lars-Petter; Lie Høivik, Marte; Moum, Bjørn; Opheim, Randi; Huppertz-Hauss, Gert; Grimstad, Tore; Berset, Ingrid Prytz; Frigstad, Svein Oskar; Hovde, Øistein & Bernklev, Tomm (2015). Fatigue is associated with increased pain intensity and interference in IBD. Inflammatory Bowel Diseases.  ISSN 1078-0998. . doi: 10.1080/00365521
• Hovde, Øistein (2013, 10. juli). Gjøviklege med ny forskning - Vekker oppsikt.  Oppland Arbeiderblad.
• Hovde, Øistein & Moum, Bjørn (2013). Langtidsoppfølging av pasienter med Crohns sykdom - IBSEN-studien finner bedre progose enn tidligere antatt. BestPractice.  9, s 7- 9
• Hauge, Truls; Flø, Reinhardt W & Hovde, Øistein (2005). Praksisveileder – sykehus. Utplasseringen på lokalsykehus i 10. semester.

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