Ola Didrik Saugstad

• Omer, Murwan; Melo, Ashanty Maggvie; Kelly, Lynne; Mac Dermott, Emma Jane; Leahy, Timothy Ronan; Killeen, Orla; Saugstad, Ola Didrik; Savani, Rashmin C. & Molloy, Eleanor J. (2021). Emerging Role of the NLRP3 Inflammasome and Interleukin-1β in Neonates. Neonatology.  ISSN 1661-7800.  117(5), s 545- 554 . doi: 10.1159/000507584
• Saugstad, Ola Didrik; Robertson, Nicola J. & Vento, Maximo (2021). A critical review of the 2020 International Liaison Committee on Resuscitation treatment recommendations for resuscitating the newly born infant. Acta Paediatrica.  ISSN 0803-5253.  110(4), s 1107- 1112 . doi: 10.1111/apa.15754
• Solevåg, Anne Lee & Saugstad, Ola Didrik (2021). 50 Years Ago in THE JOURNAL OF PEDIATRICS: Diagnostic Utility of the Newborn Electrocardiogram. Journal of Pediatrics.  ISSN 0022-3476.  229, s 32 . doi: 10.1016/j.jpeds.2020.08.073
• Andresen, Jannicke Hanne & Saugstad, Ola Didrik (2020). Oxygen metabolism and oxygenation of the newborn. Seminars in Fetal & Neonatal Medicine.  ISSN 1744-165X.  25:101078(2), s 1- 5 . doi: 10.1016/j.siny.2020.101078 Fulltekst i vitenarkiv.
• Dypvik, Johanne; Larsen, Sandra; Haavaldsen, Camilla; Saugstad, Ola Didrik & Eskild, Anne (2020). Placental Weight and Risk of Neonatal Death. JAMA pediatrics.  ISSN 2168-6203.  174(2), s 197- 199 . doi: 10.1001/jamapediatrics.2019.4556
• Haumont, Dominique; Modi, Neena; Saugstad, Ola Didrik; Antetere, Rosine; NguyenBa, Cuong; Turner, Mark; Costeloe, Kate & Aelvoet, Willem (2020). Evaluating preterm care across Europe using the eNewborn European Network database. Pediatric Research.  ISSN 0031-3998.  88(3), s 484- 495 . doi: 10.1038/s41390-020-0769-x
• Innerdal, Mari; Simaga, I.; Diall, H.; Eielsen, M.; Niermeyer, Susan; Eielsen, Olav V & Saugstad, Ola Didrik (2020). Reduction in perinatal mortality after implementation of HBB training at a district hospital in Mali. Journal of Tropical Pediatrics.  ISSN 0142-6338.  66(3), s 315- 321 . doi: 10.1093/tropej/fmz072
• Lande, Asgeir; Fluge, Øystein; Strand, Elin Bolle; Flåm, Siri Tennebø; Daysi Duarte, Sosa; Mella, Olav; Egeland, Torstein; Saugstad, Ola Didrik; Lie, Benedicte Alexandra & Viken, Marte K (2020). Human Leukocyte Antigen Alleles Associated With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Scientific Reports.  ISSN 2045-2322.  10:5267(1), s 1- 8 . doi: 10.1038/s41598-020-62157-x Fulltekst i vitenarkiv.
• Rajar, Polona; Saugstad, Ola Didrik; Berild, Dag; Dutta, Anirban; Greisen, Gorm; Lausten-Thomsen, Ulrik; Mande, Sharmila S.; Nangia, Sushma; Petersen, Fernanda Cristina; Dahle, Ulf R & Haaland, Kirsti (2020). Antibiotic stewardship in premature infants: a systematic review. Neonatology.  ISSN 1661-7800.  117(6), s 673- 686 . doi: 10.1159/000511710 Fulltekst i vitenarkiv.
• Saugstad, Ola Didrik (2020). Acetaminophen and the Developing Brain: Reason for Concern?. Neonatology.  ISSN 1661-7800.  117(2), s 245- 248 . doi: 10.1159/000505954
• Saugstad, Ola Didrik (2020). What did I learn as a neonatologist over 40 years and what impact did Napoleon have on modern newborn medicine?. Acta Paediatrica.  ISSN 0803-5253.  109(5), s 877- 879 . doi: 10.1111/apa.15170
• Zasada, Magdalena; Madetko-Talowska, Anna; Revhaug, Cecilie; Rognlien, Anne Gro Wesenberg; Baumbusch, Lars Oliver; Książek, Teofila; Szewczyk, Katarzyna; Grabowska, Agnieszka; Bik-Multanowski, Miroslaw; Józef Pietrzyk, Jacek; Kwinta, Przemko & Saugstad, Ola Didrik (2020). Transcriptome analysis reveals dysregulation of genes involved in oxidative phosphorylation in a murine model of retinopathy of prematurity. Pediatric Research.  ISSN 0031-3998.  88(3), s 391- 397 . doi: 10.1038/s41390-020-0793-x
• Andresen, Jannicke Hanne & Saugstad, Ola Didrik (2019). 50 Years Ago in THE JOURNAL OF PEDIATRICS: Acid-Base Monitoring of the Fetus during Labor with Blood Obtained from the Scalp. Journal of Pediatrics.  ISSN 0022-3476.  208, s 140- - . doi: 10.1016/j.jpeds.2018.11.006
• Andresen, Jannicke Hanne & Saugstad, Ola Didrik (2019). 50 Years Ago in THE JOURNAL OF PEDIATRICS: Lung Expansion and Ventilation During Resuscitation of Asphyxiated Newborn Infants. Journal of Pediatrics.  ISSN 0022-3476. . doi: 10.1016/j.jpeds.2019.01.030
• Andresen, Jannicke Hanne & Saugstad, Ola Didrik (2019). 50 Years Ago in THE JOURNAL OF PEDIATRICS: Polycythemia in Small for Gestational Age Infants. Journal of Pediatrics.  ISSN 0022-3476.  214, s 140- 140 . doi: 10.1016/j.jpeds.2019.04.038
• Andresen, Jannicke Hanne & Saugstad, Ola Didrik (2019). 50 Years Ago in THE JOURNAL OF PEDIATRICS: Positive Pressure Ventilation in the Newborn Infant: The Use of a Face Mask. Journal of Pediatrics.  ISSN 0022-3476. . doi: 10.1016/j.jpeds.2019.08.054
• Andresen, Jannicke Hanne & Saugstad, Ola Didrik (2019). 50 Years Ago in THE JOURNAL OF PEDIATRICS: The Effect of Pentobarbital Anesthesia on Resuscitation and Brain Damage in Fetal Rhesus Monkeys Asphyxiated on Delivery. Journal of Pediatrics.  ISSN 0022-3476. . doi: 10.1016/j.jpeds.2019.02.001
• Andresen, Jannicke Hanne & Saugstad, Ola Didrik (2019). 50 Years Ago in THE JOURNAL OF PEDIATRICS: The Use of Acid-Base Measurements in the Clinical Evaluation and Treatment of the Sick Neonate. Journal of Pediatrics.  ISSN 0022-3476.  207, s 197 . doi: 10.1016/j.jpeds.2018.10.029
• Andresen, Jannicke Hanne & Saugstad, Ola Didrik (2019). 50 Years Ago in The Journal of Pediatrics: Intrauterine Growth of Live-Born Caucasian Infants at Sea Level: Standards Obtained from Measurements in 7 Dimensions of Infants Born between 25 and 44 Weeks of Gestation. Journal of Pediatrics.  ISSN 0022-3476.  209, s 211 . doi: 10.1016/j.jpeds.2018.12.035
• Huun, Marianne Ullestad; Garberg, Håvard Tetlie; Buonocore, Giuseppe; Longini, Mariangela; Belvisi, Elisa; Bazzini, Francesco; Proietti, Fabrizio; Saugstad, Ola Didrik & Solberg, Rønnaug (2019). Regional differences of hypothermia on oxidative stress following hypoxia-ischemia: a study of DHA and hypothermia on brain lipid peroxidation in newborn piglets. Journal of Perinatal Medicine.  ISSN 0300-5577.  47(1), s 82- 89 . doi: 10.1515/jpm-2017-0355 Fulltekst i vitenarkiv.
• Marshall, Stephanie; Lang, Astri Maria; Perez, Marta & Saugstad, Ola Didrik (2019). Delivery room handling of the newborn. Journal of Perinatal Medicine.  ISSN 0300-5577.  48(1), s 1- 10 . doi: 10.1515/jpm-2019-0304 Fulltekst i vitenarkiv.
• Perez, Marta; Robbins, Mary E.; Revhaug, Cecilie & Saugstad, Ola Didrik (2019). Oxygen radical disease in the newborn, revisited: Oxidative stress and disease in the newborn period. Free Radical Biology & Medicine.  ISSN 0891-5849.  142, s 61- 72 . doi: 10.1016/j.freeradbiomed.2019.03.035 Vis sammendrag

  Thirty years ago, there was an emerging appreciation for the significance of oxidative stress in newborn disease. This prompted a renewed interest in the impact of oxygen therapy for the newborn in the delivery room and beyond, especially in premature infants. Today, the complexity of oxidative stress both in normal regulation and pathology is better understood, especially as it relates to neonatal mitochondrial oxidative stress responses to hyperoxia. Mitochondria are recipients of oxidative damage and have a propensity for oxidative self-injury that has been implicated in the pathogenesis of neonatal lung diseases. Similarly, both intrauterine growth restriction (IUGR) and macrosomia are associated with mitochondrial dysfunction and oxidative stress. Additionally, reoxygenation with 100% O2 in a hypoxic-ischemic newborn lamb model increased the production of pro-inflammatory cytokines in the brain. Moreover, the interplay between inflammation and oxidative stress in the newborn is better understood because of animal studies. Transcriptomic analyses have found a number of genes to be differentially expressed in murine models of bronchopulmonary dysplasia (BPD). Epigenetic changes have also been detected both in animal models of BPD and premature infants exposed to oxygen. Antioxidant therapy to prevent newborn disease has not been very successful; however, new therapeutic principles, like melatonin, are under investigation. Graphical abstract Image 1Download high-res image (162KB) Download full-size image Keywords Antioxidant therapy; Bronchopulmonary dysplasia (BPD); Epigenetic changes; Growth; Gene-differentiation; Inflammation mitochondria; Newborn; Oxidative stress; Persistent pulmonary hypertension of the newborn (PPHN) Abbreviations BPD bronchopulmonary dysplasia CAT catalase CuZnSOD intracellular SOD ecSOD extracellular SOD eNOS endothelial Nitric Oxide Synthase GPx glutathione peroxidase GSH glutathione GSSG/GSH Oxidized to Reduced Glutathione H2O2 hydrogen peroxide HI hypoxia-ischemia HIE hypoxic-ischemic encephalopathy HLI hyperoxic lung injury HO• hydroxyl radical iNOS intracellular nitric oxide synthase IUGR intrauterine growth restriction LGA large for gestational age MDA malondialdehyde MnSOD mitochondrial superoxide dismutase NEC necrotizing enterocolitis NO nitric oxide NOS nitric oxide synthase O2• − superoxide radical ONOO− peroxynitrite OS oxidative stress PDE5 phosphodiesterase-5 PPHN persistent pulmonary hypertension of the newborn rhSOD recombinant human-CuZnSOD ROS reactive oxygen species SGA small for gestational age SOD superoxide dismutase UPI uteroplacental insufficiency

• Rajar, Polona; Atneosen-Åsegg, Monica; Saugstad, Ola Didrik; Solberg, Rønnaug & Baumbusch, Lars Oliver (2019). Quantification of circulating cell-free DNA (cfDNA) in urine using a newborn piglet model of asphyxia. PLOS ONE.  ISSN 1932-6203.  14 (12), s 1- 14 . doi: 10.1371/journal.pone.0227066 Fulltekst i vitenarkiv.
• Revhaug, Cecilie; Bik-Multanowski, Miroslaw; Zasada, Magdalena; Rognlien, Anne Gro Wesenberg; Günther, Clara-Cecilie; Ksiazek, Teofila; Madetko-Talowska, Anna; Szewczyk, Katarzyna; Grabowska, Agnieszka; Kwinta, Przemko; Pietrzyk, Jacek Jozef; Baumbusch, Lars Oliver & Saugstad, Ola Didrik (2019). Immune System Regulation Affected by a Murine Experimental Model of Bronchopulmonary Dysplasia: Genomic and Epigenetic Findings. Neonatology.  ISSN 1661-7800.  116, s 269- 277 . doi: 10.1159/000501461 Fulltekst i vitenarkiv. Vis sammendrag

  Background: Bronchopulmonary dysplasia (BPD) is a common cause of abrupted lung development after preterm birth. BPD may lead to increased rehospitalization, more severe and frequent respiratory infections, and life-long reduced lung function. The gene regulation in lungs with BPD is complex, with various genetic and epigenetic factors involved. Objectives: The aim of this study was to examine the regulatory relation between gene expression and the epigenome (DNA methylation) relevant for the immune system after hyperoxia followed by a recovery period in air using a mouse model of BPD. Methods: Newborn mice pups were subjected to an immediate hyperoxic condition from birth and kept at 85% O2 levels for 14 days followed by a 14-day period in room air. Next, mice lung tissue was used for RNA and DNA extraction with subsequent microarray-based assessment of lung transcriptome and supplementary methylome analysis. Results:The immune system-related transcriptomeregulation was affected in mouse lungs after hyperoxia. A high proportion of genes relevant in the immune system exhibited significant expression alterations, e.g., B cell-specific genes central to the cytokine-cytokine receptor interaction, the PI3K-AKT, and the B cell receptor signaling pathways. The findings were accompanied by significant DNA hypermethylation observed in the PI3K-AKT pathway and immune system-relevant genes. Conclusions: Oxygen damage could be partly responsible for the increased susceptibility and abnormal response to respiratory viruses and infections seen in premature babies with BPD through dysregulated genes.

• Revhaug, Cecilie; Zasada, Magdalena; Rognlien, Anne Gro Wesenberg; Günther, Clara-Cecilie; Grabowska, Agnieszka; Książek, Teofila; Madetko-Talowska, Anna; Szewczyk, Katarzyna; Bik-Multanowski, Miroslaw; Kwinta, Przemko; Pietrzyk, Jacek Józef; Baumbusch, Lars Oliver & Saugstad, Ola Didrik (2019). Pulmonary vascular disease is evident in gene regulation of experimental bronchopulmonary dysplasia. Journal of Maternal-Fetal & Neonatal Medicine.  ISSN 1476-7058. . doi: 10.1080/14767058.2018.1541081 Fulltekst i vitenarkiv. Vis sammendrag

  Objective: To examine the gene expression regarding pulmonary vascular disease in experimental bronchopulmonary dysplasia in young mice. Premature delivery puts babies at risk of severe complications. Bronchopulmonary dysplasia (BPD) is a common complication of premature birth leading to lifelong affection of pulmonary function. BPD is recognized as a disease of arrested alveolar development. The disease process is not fully described and no complete cure or prevention is known. The focus of interest in the search for treatment and prevention of BPD has traditionally been at airspace level; however, the pulmonary vasculature is increasingly acknowledged in the pathology of BPD. The aim of the investigation was to study the gene expression in lungs with BPD with regards to pulmonary vascular disease (PVD). Methods: We employed a murine model of hyperoxia-induced BPD and gene expression microarray technique to determine the mRNA expression in lung tissue from young mice. We combined gene expression pathway analysis and analyzed the biological function of multiple single gene transcripts from lung homogenate to study the PVD relevant gene expression. Results: There were n = 117 significantly differentially regulated genes related to PVD through down-regulation of contractile elements, up- and down-regulation of factors involved in vascular tone and tissue-specific genes. Several genes also allowed for pinpointing gene expression differences to the pulmonary vasculature. The gene Nppa coding for a natriuretic peptide, a potent vasodilator, was significantly down-regulated and there was a significant up-regulation of Pde1a (phosphodiesterase 1A), Ptger3 (prostaglandin e receptor 3), and Ptgs1 (prostaglandin-endoperoxide synthase one). Conclusion: The pulmonary vasculature is affected by the arrest of secondary alveolarization as seen by differentially regulated genes involved in vascular tone and pulmonary vasculature suggesting BPD is not purely an airspace disease. Clues to prevention and treatment may lie in the pulmonary vascular system.

• Rognlien, Anne Gro Wesenberg; Wollen, Embjørg Julianne; Atneosen-Åsegg, Monica; Suganthan, Rajikala; Bjørås, Magnar & Saugstad, Ola Didrik (2019). Neonatal Ogg1/Mutyh knockout mice have altered inflammatory gene response compared to wildtype mice in the brain and lung after hypoxia-reoxygenation. Journal of Perinatal Medicine.  ISSN 0300-5577.  47(1), s 114- 124 . doi: 10.1515/jpm-2018-0172 Fulltekst i vitenarkiv.
• Saugstad, Ola Didrik; Oei, Ju Lee; Lakshminrusimha, Satyan & Vento, Maximo (2019). Oxygen therapy of the newborn from molecular understanding to clinical practice. Pediatric Research.  ISSN 0031-3998.  85(1), s 20- 29 . doi: 10.1038/s41390-018-0176-8 Fulltekst i vitenarkiv.
• Sweet, David G.; Carnielli, Virgilio; Greisen, Gorm; Hallman, Mikko; Ozek, Eren; te Pas, Arjan B; Plavka, Richard; Roehr, Charles Christoph; Saugstad, Ola Didrik; Simeoni, Umberto; Speer, Christian P.; Vento, Maximo; Visser, Gerard H.A. & Halliday, Henry L. (2019). European Consensus Guidelines on the Management of Respiratory Distress Syndrome - 2019 Update. Neonatology.  ISSN 1661-7800.  115(4), s 432- 450 . doi: 10.1159/000499361 Fulltekst i vitenarkiv.
• Vento, Máximo & Saugstad, Ola Didrik (2019). Targeting oxygen in term and preterm infants starting at birth. Clinics in Perinatology.  ISSN 0095-5108.  46(3), s 459- 473 . doi: 10.1016/j.clp.2019.05.013
• Xu, Zongli; Lie, Rolv T.; Wilcox, Allen J.; Saugstad, Ola Didrik & Taylor, Jack A. (2019). A comparison of DNA methylation in newborn blood samples from infants with and without orofacial clefts. Clinical Epigenetics.  ISSN 1868-7075.  11(40) . doi: 10.1186/s13148-019-0638-9 Fulltekst i vitenarkiv.
• Ystgaard, Martin Bogale; Scheffler, Katja; Suganthan, Rajikala; Bjørås, Magnar; Ranheim, Trine; Sagen, Ellen Lund; Halvorsen, Bente; Saugstad, Ola Didrik & Yndestad, Arne (2019). Neuromodulatory effect of NLRP3 and ASC in neonatal hypoxic ischemic encephalopathy. Neonatology.  ISSN 1661-7800.  115(4), s 355- 362 . doi: 10.1159/000497200 Fulltekst i vitenarkiv. Vis sammendrag

  Background: Following birth asphyxia there is a robust inflammatory response. NLRP3 is a receptor of the innate immune system. Upon activation, NLRP3 forms an inflammasome together with ASC and procaspase-1 to mediate release of IL-1β and IL-18. NLRP3 has previously been shown to be upregulated following neonatal hypoxic-ischemic (HI) brain injury in mice, but with no early effect on brain injury. Objective: We aimed to evaluate if deficiency of NLRP3 or ASC protects against neonatal HI brain damage 7 days after hypoxia-ischemia. Methods: C57BL/6J, NLRP3–/–, and ASC–/– mice were subjected to unilateral common carotid artery ligation followed by hypoxia at P9. Brain infarction, apoptosis, and microglial response were evaluated, as well as total RNA sequencing and examination of plasma levels of systemic proinflammatory cytokines. Results: NLRP3–/– mice showed significantly increased brain infarction volumes compared to wild-type (Wt) mice, while ASC–/– mice showed reduced brain infarction volumes after neonatal hypoxia-ischemia. The amount of activated microglia was increased in NLRP3–/– mice, while decreased in ASC–/– mice compared to Wt mice. Total RNA sequencing showed an impaired inflammatory transcriptional response in the hippocampus of NLRP3–/– mice. Plasma levels of IL-1β and IL-18 were not affected, but TNF was lower in NLRP3–/– and ASC–/– mice compared to Wt mice. Conclusion: ASC deficiency is neuroprotective in neonatal HI brain damage in mice, while NLRP3 deficiency increases brain damage.

• Zasada, Magdalena; Madetko-Talowska, Anna; Revhaug, Cecilie; Rognlien, Anne Gro Wesenberg; Baumbusch, Lars Oliver; Książek, Teofila; Szewczyk, Katarzyna; Grabowska, Agnieszka; Bik-Multanowski, Miroslaw; Józef Pietrzyk, Jacek; Kwinta, Przemko & Saugstad, Ola Didrik (2019). Short- and long-term impact of hyperoxia on the blood and retinal cells' transcriptome in a mouse model of oxygen-induced retinopathy. Pediatric Research.  ISSN 0031-3998.  87, s 485- 493 . doi: 10.1038/s41390-019-0598-y Fulltekst i vitenarkiv.
• Zasada, Magdalena; Suski, Maciej; Bokiniec, Renata; Szwarc-Duma, Monika; Borszewska-Kornacka, Maria Katarzyna; Madej, Józef; Bujak-Giżycka, Beata; Madetko-Talowska, Anna; Revhaug, Cecilie; Baumbusch, Lars O.; Saugstad, Ola Didrik; Pietrzyk, Jacek Józef & Kwinta, Przemko (2019). Comparative two time-point proteome analysis of the plasma from preterm infants with and without bronchopulmonary dysplasia. The Italian Journal of Pediatrics.  ISSN 1720-8424.  45(112), s 1- 9 . doi: 10.1186/s13052-019-0676-0 Fulltekst i vitenarkiv.
• Benterud, Torkil; Manueldas, Sophia; Rivera, Santiago; Henckel, Ewa; Løberg, Else Marit; Norgren, Svante; Baumbusch, Lars Oliver; Solberg, Rønnaug & Saugstad, Ola Didrik (2018). Cerebellum Susceptibility to Neonatal Asphyxia: Possible Protective Effects of N-Acetylcysteine Amide. Disease Markers.  ISSN 0278-0240.  2018(5046372) . doi: 10.1155/2018/5046372 Fulltekst i vitenarkiv.
• Bik-Multanowski, Miroslaw; Revhaug, Cecilie; Grabowska, Agnieszka; Dobosz, Artur; Madetko-Talowska, Anna; Zasada, Magdalena & Saugstad, Ola Didrik (2018). Hyperoxia induces epigenetic changes in newborn mice lungs. Free Radical Biology & Medicine.  ISSN 0891-5849.  121, s 51- 56 . doi: 10.1016/j.freeradbiomed.2018.04.566
• Bryn, Vesna; Verkerk, Robert; Skjeldal, Ola; Saugstad, Ola Didrik & Ormstad, Heidi Kristin (2018). Kynurenine pathway in autism spectrum disorders in children. Neuropsychobiology.  ISSN 0302-282X.  76(2), s 82- 88 . doi: 10.1159/000488157 Fulltekst i vitenarkiv. Vis sammendrag

  Background: There is increasing evidence that altered immune responses play a role in the pathogenesis of autism spectrum disorders (ASD), together with dysfunction of the serotonergic and glutamatergic systems. Since the kynurenine (KYN) pathway that degrades tryptophan (TRP) is activated in various neuroinflammatory states, we aimed to determine whether this pathway is activated in ASD. Methods: Sixty-five pediatric ASD patients (including 52 boys) were enrolled from an epidemiological survey covering 2 counties in Norway; 30 (46.5%) of these patients were diagnosed with childhood autism, 16 (24.6%) with Asperger syndrome, 12 (18.5%) with atypical autism, 1 (1.5%) with Rett syndrome, and 6 (9.2%) with other ASD. The serum levels of the following markers were measured in the children with ASD and compared to those in 30 healthy children: TRP, KYN, kynurenic acid (KA), 3-hydroxykynurenine, and quinolinic acid. Results: The mean serum level of KA was significantly lower in the ASD group than in the healthy controls (28.97 vs. 34.44 nM, p = 0.040), while the KYN/KA ratio was significantly higher in the ASD group (61.12 vs. 50.39, p = 0.006). The same relative values were found when comparing the childhood autism subgroup with the controls. Also, the mean serum level of TRP was significantly lower in children with a subdiagnosis of childhood autism than in those with Asperger syndrome (67.26 vs. 77.79 μM, p = 0.020). Conclusion: Our study indicates that there is an increased neurotoxic potential and also a possible lower KYN aminotransferase activity in ASD.

• de Lange, Charlotte; Solberg, Rønnaug; Holtedahl, Jon Erik; Tulipan, Andreas Julius; Barlinn, Jon; Trigg, William; Wickstrøm, Torild; Saugstad, Ola Didrik; Malinen, Eirik & Rootwelt-Revheim, Mona-Elisabeth (2018). Dynamic TSPO-PET for assessing early effects of cerebral hypoxia and resuscitation in new born pigs. Nuclear Medicine and Biology.  ISSN 0969-8051.  66, s 49- 57 . doi: 10.1016/j.nucmedbio.2018.08.004
• Garcia-Hidalgo, Catalina; Cheung, Po-Yin; Solevåg, Anne Lee; Vento, Máximo; O´Reilly, Megan; Saugstad, Ola Didrik & Schmölzer, Georg M. (2018). A review of oxygen use during chest compressions in Newborns-A meta-analysis of animal data. Frontiers in pediatrics.  ISSN 2296-2360.  6:400, s 1- 7 . doi: 10.3389/fped.2018.00400 Fulltekst i vitenarkiv.
• Huun, Marianne Ullestad; Garberg, Håvard Tetlie; Løberg, Else Marit; Escobar, Javier; Martinez-Orgado, Jose; Saugstad, Ola Didrik & Solberg, Rønnaug (2018). DHA and therapeutic hypothermia in a short-term follow-up piglet model of hypoxia-ischemia: Effects on H+MRS biomarkers. PLOS ONE.  ISSN 1932-6203.  13:e0201895(8), s 1- 15 . doi: 10.1371/journal.pone.0201895 Fulltekst i vitenarkiv.
• Manueldas, Sophia; Benterud, Torkil; Rueegg, Corina Silvia; Garberg, Håvard Tetlie; Huun, Marianne Ullestad; Pankratov, Leonid; Atneosen-Åsegg, Monica; Solberg, Rønnaug; Escobar, Javier; Saugstad, Ola Didrik & Baumbusch, Lars Oliver (2018). Temporal patterns of circulating cell-free DNA (cfDNA) in a newborn piglet model of perinatal asphyxia. PLOS ONE.  ISSN 1932-6203.  13:e0206601(11), s 1- 20 . doi: 10.1371/journal.pone.0206601 Fulltekst i vitenarkiv.
• Oei, Ju Lee; Finer, Neil; Saugstad, Ola Didrik; Wright, Ian M.; Rabi, Yacov; Tarnow-Mordi, William; Rich, Wade; Kapadia, Vishal; Rook, Denise; Smyth, John P.; Lui, Kei & Vento, Máximo (2018). Outcomes of oxygen saturation targeting during delivery room stabilisation of preterm infants. Archives of Disease in Childhood: Fetal and Neonatal Edition.  ISSN 1359-2998.  103(5), s F446- F454 . doi: 10.1136/archdischild-2016-312366
• Oei, Ju Lee; Saugstad, Ola Didrik & Vento, Máximo (2018). Oxygen and preterm infant resuscitation: What else do we need to know?. Current opinion in pediatrics.  ISSN 1040-8703.  30(2), s 192- 198 . doi: 10.1097/MOP.0000000000000610
• Ormstad, Heidi Kristin; Bryn, Vesna; Saugstad, Ola Didrik; Skjeldal, Ola & Maes, Michael (2018). Role of the immune system in autism spectrum disorders (ASD). CNS and Neurological Disorders - Drug Targets.  ISSN 1871-5273.  17(7), s 489- 495 . doi: 10.2174/1871527317666180706123229 Fulltekst i vitenarkiv.
• Ormstad, Heidi Kristin; Bryn, Vesna; Verkerk, Robert; Skjeldal, Ola; Halvorsen, Bente; Saugstad, Ola Didrik; Isaksen, Jørn & Maes, Michael (2018). Serum Tryptophan, Tryptophan Catabolites and Brain-derived Neurotrophic Factor in Subgroups of Youngsters with Autism Spectrum Disorders. CNS and Neurological Disorders - Drug Targets.  ISSN 1871-5273.  17(8), s 626- 639 . doi: 10.2174/1871527317666180720163221 Fulltekst i vitenarkiv.
• Saugstad, Ola Didrik (2018). 50 Years Ago in THE JOURNAL OF PEDIATRICS: Alveolar Arterial Oxygen Gradient in Premature Infants Breathing 100% Oxygen. Journal of Pediatrics.  ISSN 0022-3476.  194, s 66 . doi: 10.1016/j.jpeds.2017.06.017
• Saugstad, Ola Didrik (2018). 50 Years Ago in THE JOURNAL OF PEDIATRICS: Birth Weight, Gestational Age, and Sex as Determining Factors in the Incidence of Respiratory Distress Syndrome of Prematurely Born Infants. Journal of Pediatrics.  ISSN 0022-3476.  197, s 28 . doi: 10.1016/j.jpeds.2017.11.040
• Saugstad, Ola Didrik (2018). 50 Years Ago in THE JOURNAL OF PEDIATRICS: Phenylketonuria: Evaluation of Therapy and Verification of Diagnosis. Journal of Pediatrics.  ISSN 0022-3476.  193, s 92 . doi: 10.1016/j.jpeds.2017.12.035
• Saugstad, Ola Didrik (2018). 50 Years Ago in THE JOURNAL OF PEDIATRICS: Sudden Unexpected Death in Infancy: A Statistical Analysis of Certain Socioeconomic Factors. Journal of Pediatrics.  ISSN 0022-3476.  200, s 149 . doi: 10.1016/j.jpeds.2018.02.049
• Saugstad, Ola Didrik (2018). 50 Years Ago in THE JOURNAL OF PEDIATRICS: The Effect of Pretreatment with Pentobarbital, Meperidine, or Hyperbaric Oxygen on the Response to Anoxia and Resuscitation in Newborn Rabbits. Journal of Pediatrics.  ISSN 0022-3476.  195, s 168 . doi: 10.1016/j.jpeds.2017.10.025
• Saugstad, Ola Didrik (2018). 50 Years Ago in THE JOURNAL OF PEDIATRICS: Uric Acid Levels in Full-Term and Low-Birth-Weight Infants. Journal of Pediatrics.  ISSN 0022-3476.  201, s 92 . doi: 10.1016/j.jpeds.2018.03.043
• Saugstad, Ola Didrik (2018). Oxygenation of the Immature Infant: A Commentary and Recommendations for Oxygen Saturation Targets and Alarm Limits. Neonatology.  ISSN 1661-7800.  114(1), s 69- 75 . doi: 10.1159/000486751
• Saugstad, Ola Didrik (2018). Resuscitation of the Newborn, In Giuseppe Buonocore; Rodolfo Bracci & Michael Weindling (ed.),  Neonatology. A Practical Approach to Neonatal Diseases.  Springer.  ISBN 978-3-319-29487-2.  kapittel.  s 1 - 16
• Stenson, Ben & Saugstad, Ola Didrik (2018). Oxygen Treatment for Immature Infants beyond the Delivery Room: Lessons from Randomized Studies. Journal of Pediatrics.  ISSN 0022-3476.  200, s 12- 18 . doi: 10.1016/j.jpeds.2018.05.001
• Suski, Maciej; Bokiniec, Renata; Szwarc-Duma, Monika; Madej, Jozef; Bujak-Gizycka, Beata; Borszewska-Kornacka, Maria K.; Ksiazek, Teofila; Grabowska, Agnieszka; Revhaug, Cecilie; Baumbusch, Lars Oliver; Saugstad, Ola Didrik; Pietrzyk, Jacek Jozef & Kwinta, Przemko (2018). Plasma proteome changes in cord blood samples from preterm infants. Journal of Perinatology.  ISSN 0743-8346.  38, s 1182- 1189 . doi: 10.1038/s41372-018-0150-7 Fulltekst i vitenarkiv.
• Suski, Maciej; Bokiniec, Renata; Szwarc-Duma, Monika; Madej, Józef; Bujak-Giżycka, Beata; Kwinta, Przemko; Borszewska-Kornacka, Maria K.; Revhaug, Cecilie; Baumbusch, Lars Oliver; Saugstad, Ola Didrik & Pietrzyk, Jacek Józef (2018). Prospective plasma proteome changes in preterm infants with different gestational ages. Pediatric Research.  ISSN 0031-3998.  84, s 104- 111 . doi: 10.1038/s41390-018-0003-2
• Syltern, Janicke Marita; Markestad, Trond Jacob; Saugstad, Ola Didrik & Støen, Ragnhild (2018). NICU dialects: Understanding Norwegian practice variation. Pediatrics.  ISSN 0031-4005.  142, s S545- S551 . doi: 10.1542/peds.2018-0478E Fulltekst i vitenarkiv.
• Thamrin, Valerie; Saugstad, Ola Didrik; Tarnow-Mordi, William; Wang, Yueping Alex; Lui, Kei; Wright, Ian M.; De Waal, Koert; Travadi, Javeed; Smyth, John P.; Craven, Paul; McMullan, Rowena; Coates, Elisabeth; Ward, Meredith; Mishra, Parag; See, Kwee Ching; Cheah, Irene G.S.; Lim, Chin Theam; Choo, Yao Mun; Kamar, Azanna Ahmad; Cheah, Fook Choe; Masoud, Ahmed & Oei, Ju Lee (2018). Preterm infant outcomes after randomization to initial resuscitation with FiO2 0.21 or 1.0. Journal of Pediatrics.  ISSN 0022-3476.  201, s 55- 61.e1 . doi: 10.1016/j.jpeds.2018.05.053
• Thomas, Anub Mathew; Schjalm, Camilla; Nilsson, Per; Lindenskov, Paal Helge H.; Rørtveit, Runa; Solberg, Rønnaug; Saugstad, Ola Didrik; Berglund, Magnus M.; Strömberg, Patrik; Lau, Corinna; Espevik, Terje; Jansen, Johan Høgset; Castellheim, Albert; Mollnes, Tom Eirik & Barratt-Due, Andreas (2018). Combined Inhibition of C5 and CD14 Attenuates Systemic Inflammation in a Piglet Model of Meconium Aspiration Syndrome. Neonatology.  ISSN 1661-7800.  113(4), s 322- 330 . doi: 10.1159/000486542 Fulltekst i vitenarkiv.
• Umphrey, Lisa; Breindahl, Morten; Brown, Alexandra; Saugstad, Ola Didrik; Thio, Marta; Trevisanuto, Daniele; Roehr, Charles Christoph & Blennow, Mats (2018). When Helping Babies Breathe Is Not Enough: Designing a Novel, Mid-Level Neonatal Resuscitation Algorithm for Medecins Sans Frontieres Field Teams Working in Low-Resource Hospital Settings. Neonatology.  ISSN 1661-7800.  114(2), s 112- 123 . doi: 10.1159/000486705 Fulltekst i vitenarkiv.
• Wilson, A; Vento, M; Shah, Prakesh S.; Saugstad, Ola Didrik; Finer, Neil; Rich, Wade; Morton, Rachael L.; Rabi, Yacov; Tarnow-Mordi, William; Suzuki, Keiji; Wright, Ian M. & Oei, Ju Lee (2018). A review of international clinical practice guidelines for the use of oxygen in the delivery room resuscitation of preterm infants. Acta Paediatrica.  ISSN 0803-5253.  107(1), s 20- 27 . doi: 10.1111/apa.14012
• Zasada, Magdalena; Suski, Maciej; Bokiniec, Renata; Szwarc-Duma, Monika; Borszewska-Kornacka, Maria Katarzyna; Madej, Józef; Bujak-Giżycka, Beata; Madetko-Talowska, Anna; Revhaug, Cecilie; Baumbusch, Lars Oliver; Saugstad, Ola Didrik; Pietrzyk, Jacek Józef & Kwinta, Przemko (2018). An iTRAQ-based quantitative proteomic analysis of plasma proteins in preterm newborns with retinopathy of prematurity. Investigative Ophthalmology and Visual Science.  ISSN 0146-0404.  59(13), s 5312- 5319 . doi: 10.1167/iovs.18-24914 Fulltekst i vitenarkiv. Vis sammendrag

  Purpose: Retinopathy of prematurity (ROP) is a vision-threatening complication of a premature birth, in which the etiology still remains unclear. Importantly, the molecular processes that govern these effects can be investigated in a perturbed plasma proteome composition. Thus, plasma proteomics may add new insights into a better understanding of the pathogenesis of this disease. Methods: The cord and peripheral blood of neonates (≤30 weeks gestational age) was drawn at birth and at the 36th postmenstrual week (PMA), respectively. Blood samples were retrospectively subdivided into ROP(+) and ROP(−) groups, according to the development of ROP. Results: The quantitative analysis of plasma proteome at both time points revealed 30 protein abundance changes between ROP(+) and ROP(−) groups. After standardization to gestational age, children who developed ROP were characterized by an increased C3 complement component and fibrinogen level at both analyzed time points. Conclusions: Higher levels of the complement C3 component and fibrinogen, present in the cord blood and persistent to 36 PMA, may indicate a chronic low-grade systemic inflammation and hypercoagulable state that may play a role in the development of ROP.

• Asadi-Azarbaijani, Babak; Santos, Regiane R.; Jahnukainen, Kirsi; Braber, Saskia; van Duursen, Majorie BM; Toppari, Jorma; Saugstad, Ola Didrik; Nurmio, Mirja & Oskam, Irma Caroline (2017). Developmental effects of imatinib mesylate on follicle assembly and early activation of primordial follicle pool in postnatal rat ovary. Reproductive Biology.  ISSN 1642-431X.  17(1), s 25- 33 . doi: 10.1016/j.repbio.2016.11.003
• Aune, Dagfinn; Schlesinger, Sabrina; Henriksen, Tore; Saugstad, Ola Didrik & Tonstad, Serena (2017). Physical activity and the risk of preterm birth: a systematic review and meta-analysis of epidemiological studies. BJOG: An International Journal of Obstetrics and Gynaecology.  ISSN 1470-0328.  124(12), s 1816- 1826 . doi: 10.1111/1471-0528.14672
• de Lange, Charlotte; Saugstad, Ola Didrik & Solberg, Rønnaug (2017). Assessment of cerebral perfusion with contrast-enhanced ultrasound during constriction of the neck mimicking malposition of the BD Odon Device™: a study in newborn piglets. BJOG: An International Journal of Obstetrics and Gynaecology.  ISSN 1470-0328.  124(S4), s 26- 34 . doi: 10.1111/1471-0528.14751
• Garberg, Håvard Tetlie; Huun, Marianne Ullestad; Baumbusch, Lars Oliver; Atneosen-Åsegg, Monica; Solberg, Rønnaug & Saugstad, Ola Didrik (2017). Temporal Profile of Circulating microRNAs after Global Hypoxia-Ischemia in Newborn Piglets. Neonatology.  ISSN 1661-7800.  111(2), s 133- 139 . doi: 10.1159/000449032
• Garberg, Håvard Tetlie; Solberg, Rønnaug; Barlinn, Jon; Martinez-Orgado, Jose; Løberg, Else Marit & Saugstad, Ola Didrik (2017). High-dose cannabidiol induced hypotension after global hypoxia-ischemia in piglets. Neonatology.  ISSN 1661-7800.  112(2), s 143- 149 . doi: 10.1159/000471786
• Grytten, Jostein Ivar; Monkerud, Lars Chr.; Skau, Irene; Eskild, Anne; Sørensen, Rune Jørgen & Saugstad, Ola Didrik (2017). Saving Newborn Babies – The Benefits of Interventions in Neonatal Care in Norway over More Than 40 Years. Health Economics.  ISSN 1057-9230.  26(3), s 352- 370 . doi: 10.1002/hec.3314 Fulltekst i vitenarkiv.
• Huun, Marianne Ullestad; Garberg, Håvard Tetlie; Escobar, Javier; Chafer, Consuelo; Vento, Maximo; Holme, Ingar Morten K; Saugstad, Ola Didrik & Solberg, Rønnaug (2017). DHA reduces oxidative stress following hypoxia-ischemia in newborn piglets: A study of lipid peroxidation products in urine and plasma. Journal of Perinatal Medicine.  ISSN 0300-5577.  46(2), s 209- 217 . doi: 10.1515/jpm-2016-0334 Fulltekst i vitenarkiv.
• Kuligowski, Julia; Solberg, Rønnaug; Sánchez-Illana, Ángel; Pankratov, Leonid; Parra-Llorca, Anna; Quintas, Guillermo; Saugstad, Ola Didrik & Ventoa, Máximo (2017). Plasma metabolite score correlates with Hypoxia time in a newly born piglet model for asphyxia. Redox Biology.  ISSN 2213-2317.  12, s 1- 7 . doi: 10.1016/j.redox.2017.02.002
• Kwinta, Przemko; Bokiniec, Renata; Bik-Multanowski, Miroslaw; Günther, Clara-Cecilie; Grabowska, Agnieszka; Ksiazek, Teofila; Madetko-Talowska, Anna; Szewczyk, Katarzyna; Szwarc-Duma, Monika; Borszewska-Kornacka, Maria K.; Baumbusch, Lars Oliver; Revhaug, Cecilie; Saugstad, Ola Didrik & Pietrzyk, Jacek J. (2017). Comparison of whole genome expression profile between preterm and full-term newborns. Ginekologia Polska.  ISSN 0017-0011.  88(8), s 434- 441 . doi: 10.5603/GP.a2017.0080
• Manja, Veena; Saugstad, Ola Didrik & Lakshminrusimha, Satyan (2017). Oxygen saturation targets in preterm infants and outcomes at 18-24 months: A systematic review. Pediatrics.  ISSN 0031-4005.  139(1) . doi: 10.1542/peds.2016-1609
• Oei, Ju Lee; Saugstad, Ola Didrik; Lui, Kei; Wright, Ian M.; Smyth, John P.; Craven, Paul; Wang, Yueping Alex; McMullan, Rowena; Coates, Elisabeth; Ward, Meredith; Mishra, Parag; De Waal, Koert; Travadi, Javeed; See, Kwee Ching; Cheah, Irene G.S.; Lim, Chin Theam; Choo, Yao Mun; Kamar, Azanna Ahmad; Cheah, Fook Choe; Masoud, Ahmed & Tarnow-Mordi, William (2017). Targeted oxygen in the resuscitation of preterm infants, a randomized clinical trial. Pediatrics.  ISSN 0031-4005.  139(1), s 1- 11 . doi: 10.1542/peds.2016-1452
• Oei, Ju Lee; Vento, Máximo; Rabi, Yacov; Wright, Ian; Finer, Neil; Rich, Wade; Kapadia, Vishal; Aune, Dagfinn; Rook, Denise; Tarnow-Mordi, William & Saugstad, Ola Didrik (2017). Higher or lower oxygen for delivery room resuscitation of preterm infants below 28 completed weeks gestation: a meta-analysis. Archives of Disease in Childhood: Fetal and Neonatal Edition.  ISSN 1359-2998.  102(1), s F24- F30 . doi: 10.1136/archdischild-2016-310435
• Sánchez-Illana, Ángel; Solberg, Rønnaug; Lliso, Isabel; Pankratov, Leonid; Quintas, Guillermo; Saugstad, Ola Didrik; Vento, Máximo & Kuligowski, Julia (2017). Assessment of phospholipid synthesis related biomarkers for perinatal asphyxia: a piglet study. Scientific Reports.  ISSN 2045-2322.  7:40315, s 1- 11 . doi: 10.1038/srep40315
• Saugstad, Ola Didrik (2017). 50 Years Ago in THE JOURNAL OF PEDIATRICS: Effects of Hypoxemia, Hypercarbia, Acidosis, and Reduced Pulmonary Blood Flow on the Surfactant Fetal Lamb Lung. Journal of Pediatrics.  ISSN 0022-3476.  188, s 127 . doi: 10.1016/j.jpeds.2017.03.020
• Saugstad, Ola Didrik (2017). 50 Years Ago in THE JOURNAL OF PEDIATRICS: Feeding Studies in Low-Birth-Weight Infants. Journal of Pediatrics.  ISSN 0022-3476.  184, s 124 . doi: 10.1016/j.jpeds.2016.11.065
• Saugstad, Ola Didrik (2017). 50 Years Ago in THE JOURNAL OF PEDIATRICS: The Incidence of Neonatal Hypoglycemia?A Completed Survey. Journal of Pediatrics.  ISSN 0022-3476.  180, s 73- 73 . doi: 10.1016/j.jpeds.2016.08.014

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• Almaas, Runar & Saugstad, Ola Didrik (2021). 50 years ago in THE JOURNAL OF PEDIATRICS: Hepatopulmonary syndrome: Transplantation Is the big difference. Journal of Pediatrics.  ISSN 0022-3476.  229, s 69- 69 . doi: 10.1016/j.jpeds.2020.08.074
• Solevåg, Anne Lee & Saugstad, Ola Didrik (2021). 50 Years Ago in THE JOURNAL OF PEDIATRICS: The Newborn Electrocardiogram. Journal of Pediatrics.  ISSN 0022-3476.  228, s 52- 52 . doi: 10.1016/j.jpeds.2020.07.074
• Andresen, Jannicke Hanne & Saugstad, Ola Didrik (2020). 50 Years Ago in THE JOURNAL OF PEDIATRICS: Birth Weight Is More Important than Gestational Age for Long-Term Intellectual Outcome. Journal of Pediatrics.  ISSN 0022-3476.  220, s 115 . doi: 10.1016/j.jpeds.2019.11.024
• Andresen, Jannicke Hanne & Saugstad, Ola Didrik (2020). 50 Years Ago in THE JOURNAL OF PEDIATRICS: Chromosome Studies in Full Term, Low Birth Weight, Mentally Retarded Patients. Journal of Pediatrics.  ISSN 0022-3476.  218, s 56 . doi: 10.1016/j.jpeds.2019.09.032
• Andresen, Jannicke Hanne & Saugstad, Ola Didrik (2020). 50 Years Ago in THE JOURNAL OF PEDIATRICS: Developmental Outcome for Trisomy 21 Mosaicism. Journal of Pediatrics.  ISSN 0022-3476.  221, s 38- 38 . doi: 10.1016/j.jpeds.2019.12.011
• Andresen, Jannicke Hanne & Saugstad, Ola Didrik (2020). 50 Years Ago in THE JOURNAL OF PEDIATRICS: Magnesium and birth asphyxia. Journal of Pediatrics.  ISSN 0022-3476.  227, s 190- 190 . doi: 10.1016/j.jpeds.2020.10.015
• Andresen, Jannicke Hanne & Saugstad, Ola Didrik (2020). 50 Years Ago in THE JOURNAL OF PEDIATRICS: The Oxygen-Hemoglobin Equilibrium Curve and Tissue Oxygen Release. Journal of Pediatrics.  ISSN 0022-3476.  227, s 93 . doi: 10.1016/j.jpeds.2020.06.085
• Andresen, Jannicke Hanne & Saugstad, Ola Didrik (2020). 50 Years Ago in THE JOURNAL OF PEDIATRICS: Umbilical Catheters—Then and Now. Journal of Pediatrics.  ISSN 0022-3476.  227, s 156 . doi: 10.1016/j.jpeds.2020.06.082
• Andresen, Jannicke Hanne & Saugstad, Ola Didrik (2020). 50 Years Ago in THE JOURNAL OF PEDIATRICS: When the Lung Ruptures - 50 Years Ago and Today. Journal of Pediatrics.  ISSN 0022-3476.  219, s 75 . doi: 10.1016/j.jpeds.2019.10.004
• Andresen, Jannicke Hanne & Saugstad, Ola Didrik (2020). 50 Years Ago in THE JOURNAL OF PEDIATRICS: When the Newborn Remains Blue. Journal of Pediatrics.  ISSN 0022-3476.  224, s 78- 78 . doi: 10.1016/j.jpeds.2020.03.030
• Andresen, Jannicke Hanne & Saugstad, Ola Didrik (2020). 50 Years Ago in THE JOURNAL OF PEDIATRICS: Wilson-Mikity Syndrome. Journal of Pediatrics.  ISSN 0022-3476.  222, s 173- 173 . doi: 10.1016/j.jpeds.2020.01.037
• Andresen, Jannicke Hanne & Saugstad, Ola Didrik (2020). 50 Years Ago in THE JOURNAL OF PEDIATRICS: Wolf-Hirschorn Versus Cri-du-Chat Syndrome. Journal of Pediatrics.  ISSN 0022-3476.  226, s 95 . doi: 10.1016/j.jpeds.2020.06.015
• Andresen, Jannicke Hanne & Saugstad, Ola Didrik (2020). 50 Years Ago in The Journal of Pediatrics: Human Chromosomal Deletion: Two Patients with the 4p–Syndrome. Journal of Pediatrics.  ISSN 0022-3476.  216, s 72 . doi: 10.1016/j.jpeds.2019.07.020
• Andresen, Jannicke Hanne & Saugstad, Ola Didrik (2020). 50 Years Ago in The Journal of Pediatrics: Neonatal Seizures: 50 Years of Progress. Journal of Pediatrics.  ISSN 0022-3476.  225, s 230 . doi: 10.1016/j.jpeds.2020.04.014
• Andresen, Jannicke Hanne & Saugstad, Ola Didrik (2020). 50 years ago in THE JOURNAL OF PEDIATRICS: Light exposure to the immature eye. Journal of Pediatrics.  ISSN 0022-3476.  223, s 119- 119 . doi: 10.1016/j.jpeds.2020.02.011
• Stenson, Ben & Saugstad, Ola Didrik (2019). Reply. Journal of Pediatrics.  ISSN 0022-3476.  205, s 293- 294 . doi: 10.1016/j.jpeds.2018.10.055
• Herting, Egbert; Curstedt, Tore; Halliday, Henry L.; Hallman, Mikko; Saugstad, Ola Didrik & Speer, Christian P. (2018). Sharing Progress in Neonatology (SPIN): Moving towards Individualized Prenatal and Neonatal Care. Neonatology.  ISSN 1661-7800.  113, s 384- 386 . doi: 10.1159/000487623
• Rognum, Torleiv Ole; Holmen, Sigve; Opdal, Siri Hauge; Musse, Musse Ahmed; Saugstad, Ola Didrik & Stray-Pedersen, Arne (2018). Evaluation of confidence of time of death estimation by measurement of hypoxanthine and potassium sampled at the scene of death..
• Umphrey, Lisa; Blennow, Mats; Breindahl, Morten; Brown, Alexandra; Roehr, Charles Christoph; Saugstad, Ola Didrik; Thio, Marta & Trevisanuto, Daniele (2018). Navigating a mid-level gap in neonatal resuscitation. Neonatology.  ISSN 1661-7800.  114(4), s 362- 363 . doi: 10.1159/000491689
• Garberg, Håvard Tetlie; Saugstad, Ola Didrik & Solberg, Rønnaug (2017). Perinatal-Hypoxic-Ischemic Brain Injury: Detection and Intervention.
• Oei, Ju Lee; Wright, Ian M. & Saugstad, Ola Didrik (2017). Authors' response. Pediatrics.  ISSN 0031-4005.  139(5), s 1- 2 . doi: 10.1542/peds.2017-0452B
• Saugstad, Ola Didrik (2017, 26. oktober). Asphyxia in the third millennium: from Virgina Apgar to metabolomics. [Internett].  https://www.youtube.com/watch?v=ruKRWy0uP-k&t=10s.
• Saugstad, Ola Didrik (2017). Kommentar til "Fish Oil in Pregnancy and Asthma in Offspring". New England Journal of Medicine.  ISSN 0028-4793.  376 . doi: 10.1056/NEJMc1701020

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