University of Bergen - Postdoctoral Fellow (3 years)
At the Faculty of Medicine, Department of Biomedicine, a full-time position as Postdoctoral Research Fellow is available for a period of three years. The position is part of the ERC Consolidator Grant project ”Discovery and functional significance of post-translational N-terminal acetylation”, in the group of NCMM Young Associate Investigator, Thomas Arnesen.
About the project/work tasks:
- The major aim of the project is to biochemically characterize novel acetyltransferases. N-terminal acetyltransferases (NATs) couple acetyl-groups to the majority of proteins in a human cell, thus making N-terminal acetylation one of the most abundant protein modifications. See TiBS, doi: https://doi.org/10.1016/j.tibs.2016.07.005
- Our research group at UiB (https://www.uib.no/rg/nat) identified and characterized the complete known NAT-machinery in human cells. However, we believe that there are additional NATs that have central roles in our cells. By mapping these enzymes, we may increase our understanding of fundamental cellular processes with a significant impact on human disease. See Mol Cell, doi: https://doi.org/10.1016/j.molcel.2019.02.007
- The main tasks of the postdoctoral research fellow will be planning, execution and analysis of research experiments on post-translational N-terminal acetylation within the frames of this ERC-project. Both standard and advanced methods in protein biochemistry are needed to carry out this project. Thus, the researcher is expected to act as self-driven scientist with the responsibility of key parts of the ERC-project from idea to publication. At the same time, the researcher will collaborate with other members of the lab to pursue the larger goals of the project.
- The fellow is also expected to supervise students from Bachelor-level to PhD-level.