Identify novel associations between brain imaging phenotypes and clinical and genetic properties.
Advanced neuroimaging techniques including structural and functional MRI have revolutionized the understanding of the structural and functional makeup of the human brain. NORMENT researchers have contributed in the identification of structural brain abnormalities in schizophrenia, including volumetric alterations in frontotemporal cortical areas and subcortical structures. Partly overlapping and partly diverging patterns have been found in bipolar disorder.
Structural and functional brain phenotypes are highly heritable, and current research at NORMENT aims at identifying the genetic underpinnings of individual differences in the structural and functional makeup of the human brain, and to disentangle the genetic and phenotypic associations to severe neuropsyhiatric disorders.