Dag Alnæs

Forsker
Bilde av Dag Alnæs
Brukernavn
Besøksadresse Oslo Universitetssykehus Ullevål Bygg 48
Postadresse OUS Postboks 4956 Nydalen

Foto: Kirsten Sjøwall

Academic interests

My main area of interest is brain development and mental health in adolescence.

Adolescence is a major period of human development, in which biological, psychological and social changes bring about the transition from childhood into young adulthood. While these profound changes engender a period of relative instability, they also offer a major window for growth, adaptation and opportunities. For most individuals, adolescence results in successful acquirement of skills and coping strategies required for adulthood. However, it is also a period in which many mental disorders emerge for the first time (Paus, 2008). And for many, these issues persist into adulthood.

We don’t know why some individuals experience symptoms and illness, and why others don’t. The available evidence strongly supports a neurodevelopmental origin (Insel, 2010). A major goal for my research is therefore to help identify vulnerabilities in the young brain before the onset of symptoms and illness, and to understand what constitutes healthy brain development during this transitional life phase.

Unfortunately, most clinical neuroimaging research has focused on chronic stages of mental illness in adults, limiting our understanding of lifespan dynamics and the role of aberrant brain development. While large-scale case-control studies have demonstrated remarkable consistency with respect to the regional patterns of mean differences between groups of patients and controls, we recently showed that these changes are associated with substantial heterogeneity in patients (Alnæs, 2019). There may be a great potential for insights into the pathophysiology of mental disease by investigating brain development in healthy children and adolescents, as well as those presenting with sub-clinical expression of disease.

In line with this, I recently published a study where I investigated patterns of symptoms of mental illness in a large cohort of children and adolescents, and found that individual differences in symptom burden can be expressed as a cross-diagnostic and dimensional score, which is heritable and associated with brain white matter structural connections in the developing brain (Alnæs, 2018). This means that everyone can be understood as having different degrees of vulnerability for symptoms and illness, which is partly explained by genetics. In the same cohort we found that the stability of the brain’s functional connections increase during adolescence, but is delayed in adolescents with increased symptom levels (Kaufmann, 2017).

Publikasjoner

  • Cheng, Weiqiu; van der Meer, Dennis; Parker, Nadine; Hindley, Guy Frederick Lanyon; O'Connell, Kevin Sean & Wang, Yunpeng [Vis alle 20 forfattere av denne artikkelen] (2022). Shared genetic architecture between schizophrenia and subcortical brain volumes implicates early neurodevelopmental processes and brain development in childhood. Molecular Psychiatry. ISSN 1359-4184.
  • Aamodt, Eva Birgitte; Lydersen, Stian; Alnæs, Dag; SCHELLHORN, TILL; Saltvedt, Ingvild & Beyer, Mona K. [Vis alle 7 forfattere av denne artikkelen] (2022). Longitudinal Brain Changes After Stroke and the Association With Cognitive Decline. Frontiers in Neurology. ISSN 1664-2295. 13, s. 1–13. doi: 10.3389/fneur.2022.856919.
  • Pedersen, Mads Lund; Alnæs, Dag; van der Meer, Dennis; Fernandez-Cabello, Sara; Berthet, Pierre Guillaume Raphael & Dahl, Andreas [Vis alle 12 forfattere av denne artikkelen] (2022). Computational Modeling of the n-Back Task in the ABCD Study: Associations of Drift Diffusion Model Parameters to Polygenic Scores of Mental Disorders and Cardiometabolic Diseases. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. ISSN 2451-9022. doi: 10.1016/j.bpsc.2022.03.012.
  • Ulrichsen, Kristine Moe; Kolskår, Knut-Kristian; Richard, Geneviève; Pedersen, Mads Lund; Alnæs, Dag & Dørum, Erlend Solberg [Vis alle 13 forfattere av denne artikkelen] (2022). No add-on effect of tDCS on fatigue and depression in chronic stroke patients: A randomized sham-controlled trial combining tDCS with computerized cognitive training. Brain and Behavior. ISSN 2162-3279. 12(7). doi: 10.1002/brb3.2643.
  • Kolskår, Knut-Kristian; Ulrichsen, Kristine Moe; Richard, Geneviève; Dørum, Erlend Solberg; de Schotten, Michel Thiebaut & Rokicki, Jaroslav [Vis alle 12 forfattere av denne artikkelen] (2022). Structural disconnectome mapping of cognitive function in poststroke patients. Brain and Behavior. ISSN 2162-3279. doi: 10.1002/brb3.2707.
  • Barca, Maria Lage; Alnæs, Dag; Engedal, Knut; Persson, Karin Ester Torun; Eldholm, Rannveig Sakshaug & Siafarikas, Nikias Ioannis [Vis alle 11 forfattere av denne artikkelen] (2022). Brain Morphometric Correlates of Depressive Symptoms among Patients with and without Dementia. Dementia and Geriatric Cognitive Disorders Extra. ISSN 1664-5464. 12(2), s. 107–114. doi: 10.1159/000521114. Fulltekst i vitenarkiv
  • van der Meer, Dennis; Shadrin, Alexey; O'Connell, Kevin Sean; Bettella, Francesco; Djurovic, Srdjan & Wolfers, Thomas [Vis alle 17 forfattere av denne artikkelen] (2022). Boosting Schizophrenia Genetics by Utilizing Genetic Overlap With Brain Morphology. Biological Psychiatry. ISSN 0006-3223. 92(4), s. 291–298. doi: 10.1016/j.biopsych.2021.12.007. Fulltekst i vitenarkiv
  • Kjelkenes, Rikka; Wolfers, Thomas; Alnæs, Dag; van der Meer, Dennis; Pedersen, Mads Lund & Dahl, Andreas [Vis alle 12 forfattere av denne artikkelen] (2022). Mapping Normative Trajectories of Cognitive Function and Its Relation to Psychopathology Symptoms and Genetic Risk in Youth. biological psychiatry: global open science. ISSN 2667-1743. doi: 10.1016/j.bpsgos.2022.01.007.
  • Brouwer, Rachel M.; Klein, Marieke; Grasby, Katrina L.; Schnack, Hugo G.; Jahanshad, Neda & Teeuw, Jalmar [Vis alle 200 forfattere av denne artikkelen] (2022). Genetic variants associated with longitudinal changes in brain structure across the lifespan. Nature Neuroscience. ISSN 1097-6256. 25(4), s. 421–432. doi: 10.1038/s41593-022-01042-4.
  • Beck, Dani; de Lange, Ann-Marie Glasø; Alnæs, Dag; Maximov, Ivan; Pedersen, Mads Lund & Leinhard, Olof Dahlqvist [Vis alle 20 forfattere av denne artikkelen] (2022). Adipose tissue distribution from body MRI is associated with cross-sectional and longitudinal brain age in adults. NeuroImage: Clinical. ISSN 2213-1582. 33. doi: 10.1016/j.nicl.2022.102949. Fulltekst i vitenarkiv
  • de Lange, Ann-Marie Glasø; Anatürk, Melis; Rokicki, Jaroslav; Han, Laura K.M.; Franke, Katja & Alnæs, Dag [Vis alle 12 forfattere av denne artikkelen] (2022). Mind the gap: Performance metric evaluation in brain-age prediction. Human Brain Mapping. ISSN 1065-9471. doi: 10.1002/hbm.25837. Fulltekst i vitenarkiv
  • Frangou, Sophia; Agartz, Ingrid; Alnæs, Dag; Andreassen, Ole; Doan, Nhat Trung & Dørum, Erlend S. [Vis alle 13 forfattere av denne artikkelen] (2022). Cortical thickness across the lifespan: Data from 17,075 healthy individuals aged 3-90 years. Human Brain Mapping. ISSN 1065-9471. 43(1), s. 431–451. doi: 10.1002/hbm.25364.
  • Dima, Danai; Agartz, Ingrid; Alnæs, Dag; Andreassen, Ole; Doan, Nhat Trung & Dørum, Erlend Solberg [Vis alle 12 forfattere av denne artikkelen] (2022). Subcortical volumes across the lifespan: Data from 18,605 healthy individuals aged 3–90 years. Human Brain Mapping. ISSN 1065-9471. 43(1). doi: 10.1002/hbm.25320.
  • van der Meer, Dennis; Kaufmann, Tobias; Shadrin, Alexey; Makowski, Carolina; Frei, Oleksandr & Roelfs, Daniel [Vis alle 17 forfattere av denne artikkelen] (2021). The genetic architecture of human cortical folding. Science Advances. ISSN 2375-2548. 7(51), s. 1–9. doi: 10.1126/sciadv.abj9446. Fulltekst i vitenarkiv
  • Lund, Martina Jonette; Alnæs, Dag; de Lange, Ann-Marie Glasø; Andreassen, Ole; Westlye, Lars Tjelta & Kaufmann, Tobias (2021). Brain age prediction using fMRI network coupling in youths and associations with psychiatric symptoms. NeuroImage: Clinical. ISSN 2213-1582. doi: 10.1016/j.nicl.2021.102921. Fulltekst i vitenarkiv
  • Wainstein, Gabriel; Rojas-Líbano, Daniel; Medel, Vicente; Alnæs, Dag; Kolskår, Knut-Kristian & Endestad, Tor [Vis alle 11 forfattere av denne artikkelen] (2021). The ascending arousal system promotes optimal performance through mesoscale network integration in a visuospatial attentional task. Network Neuroscience. 5(4), s. 890–910. doi: 10.1162/netn_a_00205. Fulltekst i vitenarkiv
  • Hilland, Eva; Johannessen, Cecilie Haggag; Jonassen, Rune; Alnæs, Dag; Jørgensen, Kjetil Nordbø & Barth, Claudia [Vis alle 17 forfattere av denne artikkelen] (2021). Aberrant default mode connectivity in adolescents with early-onset psychosis: A resting state fMRI study. NeuroImage: Clinical. ISSN 2213-1582. 33. doi: 10.1016/j.nicl.2021.102881. Fulltekst i vitenarkiv
  • Abé, Christoph; Ching, Christopher R.K.; Liberg, Benny; Lebedev, Alexander V.; Agartz, Ingrid & Akudjedu, Theophilus N. [Vis alle 72 forfattere av denne artikkelen] (2021). Longitudinal Structural Brain Changes in Bipolar Disorder: A Multicenter Neuroimaging Study of 1232 Individuals by the ENIGMA Bipolar Disorder Working Group. Biological Psychiatry. ISSN 0006-3223. s. 1–11. doi: 10.1016/j.biopsych.2021.09.008. Fulltekst i vitenarkiv
  • Beck, Dani; de Lange, Ann-Marie G.; Pedersen, Mads L.; Alnæs, Dag; Maximov, Ivan & Voldsbekk, Irene [Vis alle 18 forfattere av denne artikkelen] (2021). Cardiometabolic risk factors associated with brain age and accelerate brain ageing. Human Brain Mapping. ISSN 1065-9471. s. 1–21. doi: 10.1002/hbm.25680. Fulltekst i vitenarkiv
  • Gutman, Boris A.; van Erp, Theo G.M.; Alpert, Kathryn I.; Ching, Christopher; Isaev, Dmitry & Ragothaman, Anjani [Vis alle 84 forfattere av denne artikkelen] (2021). A meta-analysis of deep brain structural shape and asymmetry abnormalities in 2,833 individuals with schizophrenia compared with 3,929 healthy volunteers via the ENIGMA Consortium. Human Brain Mapping. ISSN 1065-9471. doi: 10.1002/hbm.25625. Fulltekst i vitenarkiv
  • Siafarikas, Nikias Ioannis; Alnæs, Dag; Monereo Sanchez, Jennifer; Lund, Martina J.; Selbæk, Geir & Korsnes, Maria Stylianou [Vis alle 13 forfattere av denne artikkelen] (2021). Neuropsychiatric symptoms and brain morphology in patients with mild cognitive impairment and Alzheimer's disease with dementia. International Psychogeriatrics. ISSN 1041-6102. 33(11), s. 1217–1228. doi: 10.1017/S1041610221000934.
  • O'Connell, Kevin S.; Sønderby, Ida Elken; Frei, Oleksandr; van der Meer, Dennis; Athanasiu, Lavinia & Smeland, Olav Bjerkehagen [Vis alle 13 forfattere av denne artikkelen] (2021). Association between complement component 4A expression, cognitive performance and brain imaging measures in UK Biobank. Psychological Medicine. ISSN 0033-2917. s. 1–11. doi: 10.1017/S0033291721000179. Fulltekst i vitenarkiv
  • Høgestøl, Einar August; Ghezzo, Samuele; Nygaard, Gro Owren; Espeseth, Thomas; Sowa, Piotr & Beyer, Mona K. [Vis alle 10 forfattere av denne artikkelen] (2021). Functional connectivity in multiple sclerosis modelled as connectome stability: A 5-year follow-up study. Multiple Sclerosis. ISSN 1352-4585. s. 1–9. doi: 10.1177/13524585211030212. Fulltekst i vitenarkiv
  • Sanders, Anne-Marthe; Richard, Geneviève; Kolskår, Knut-Kristian; Ulrichsen, Kristine Moe; Kaufmann, Tobias & Alnæs, Dag [Vis alle 11 forfattere av denne artikkelen] (2021). Linking objective measures of physical activity and capability with brain structure in healthy community dwelling older adults. NeuroImage: Clinical. ISSN 2213-1582. 31. doi: 10.1016/j.nicl.2021.102767. Fulltekst i vitenarkiv
  • Wolfers, Thomas; Rokicki, Jaroslav; Alnæs, Dag; Berthet, Pierre; Agartz, Ingrid & Kia, Seyed Mostafa [Vis alle 14 forfattere av denne artikkelen] (2021). Replicating extensive brain structural heterogeneity in individuals with schizophrenia and bipolar disorder. Human Brain Mapping. ISSN 1065-9471. 42(8), s. 2546–2555. doi: 10.1002/hbm.25386. Fulltekst i vitenarkiv
  • Cheng, Weiqiu; Frei, Oleksandr; van der Meer, Dennis; Wang, Yunpeng; O`Connell, Kevin & Chu, Yunhan [Vis alle 20 forfattere av denne artikkelen] (2021). Genetic Association Between Schizophrenia and Cortical Brain Surface Area and Thickness. JAMA psychiatry. ISSN 2168-6238. 78(9), s. 1020–1030. doi: 10.1001/jamapsychiatry.2021.1435. Fulltekst i vitenarkiv
  • Gurholt, Tiril Pedersen; Kaufmann, Tobias; Frei, Oleksandr; Alnæs, Dag; Haukvik, Unn Kristin H. & van der Meer, Dennis [Vis alle 17 forfattere av denne artikkelen] (2021). Population-based body–brain mapping links brain morphology with anthropometrics and body composition. Translational Psychiatry. ISSN 2158-3188. doi: 10.1038/s41398-021-01414-7. Fulltekst i vitenarkiv
  • Ulrichsen, Kristine Moe; Kolskår, Knut-Kristian; Richard, Geneviève; Alnæs, Dag; Dørum, Erlend Solberg & Sanders, Anne-Marthe [Vis alle 13 forfattere av denne artikkelen] (2021). Structural brain disconnectivity mapping of post-stroke fatigue. NeuroImage: Clinical. ISSN 2213-1582. 30. doi: 10.1016/j.nicl.2021.102635. Fulltekst i vitenarkiv
  • Brecke, Vilde; Thorsen, Anders Lillevik; Ousdal, Olga Therese; Vriend, Chris; Alnæs, Dag & Hagen, Kristen [Vis alle 9 forfattere av denne artikkelen] (2021). Diffusion Tensor Imaging Before and 3 Months After Concentrated Exposure Response Prevention in Obsessive-Compulsive Disorder. Frontiers in Psychiatry. ISSN 1664-0640. 12:674020, s. 1–11. doi: 10.3389/fpsyt.2021.674020. Fulltekst i vitenarkiv
  • Roelfs, Daniel; Alnæs, Dag; Frei, Oleksandr; van der Meer, Dennis; Smeland, Olav Bjerkehagen & Andreassen, Ole Andreas [Vis alle 8 forfattere av denne artikkelen] (2021). Phenotypically independent profiles relevant to mental health are genetically correlated. Translational Psychiatry. ISSN 2158-3188. 11(1). doi: 10.1038/s41398-021-01313-x. Fulltekst i vitenarkiv
  • Alnæs, Dag; Kaufmann, Tobias; Marquand, Andre; Smith, Stephen M. & Westlye, Lars Tjelta (2020). Patterns of sociocognitive stratification and perinatal risk in the child brain. Proceedings of the National Academy of Sciences of the United States of America. ISSN 0027-8424. 117(22). doi: 10.1073/pnas.2001517117.
  • Dørum, Erlend Solberg; Kaufmann, Tobias; Alnæs, Dag; Richard, Geneviève; Kolskår, Knut-Kristian & Engvig, Andreas [Vis alle 11 forfattere av denne artikkelen] (2020). Functional brain network modeling in sub-acute stroke patients and healthy controls during rest and continuous attentive tracking. Heliyon. ISSN 2405-8440. 6:e04854(9), s. 1–11. doi: 10.1016/j.heliyon.2020.e04854. Fulltekst i vitenarkiv
  • Wierenga, Lara M.; Doucet, Gaëlle E.; Dima, Danai; Agartz, Ingrid; Aghajani, Moji & Akudjedu, Theophilus N. [Vis alle 50 forfattere av denne artikkelen] (2020). Greater male than female variability in regional brain structure across the lifespan. Human Brain Mapping. ISSN 1065-9471. doi: 10.1002/hbm.25204. Fulltekst i vitenarkiv
  • Schwarz, Emanuel; Alnæs, Dag; Andreassen, Ole Andreas; Cao, Han; Chen, Junfang & Degenhardt, Franziska [Vis alle 27 forfattere av denne artikkelen] (2020). Identifying multimodal signatures underlying the somatic comorbidity of psychosis: the COMMITMENT roadmap. Molecular Psychiatry. ISSN 1359-4184. doi: 10.1038/s41380-020-00915-z. Fulltekst i vitenarkiv
  • Hofer, Edith; Roshchupkin, Gennady V.; Adams, Hieab H H; Knol, Maria J.; Lin, Honghuang & Li, Shuo [Vis alle 51 forfattere av denne artikkelen] (2020). Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults. Nature Communications. ISSN 2041-1723. 11. doi: 10.1038/s41467-020-18367-y. Fulltekst i vitenarkiv
  • Grasby, Katrina L.; Jahanshad, Neda; Painter, Jodie N; Colodro-Conde, Lucía; Bralten, Janita & Hibar, DP [Vis alle 50 forfattere av denne artikkelen] (2020). The genetic architecture of the human cerebral cortex. Science. ISSN 0036-8075. 367(6484). doi: 10.1126/science.aay6690. Fulltekst i vitenarkiv
  • Haatveit, Beathe Christin; Mørch-Johnsen, Lynn; Alnæs, Dag; Engen, Magnus Johan; Lyngstad, Siv Hege & Færden, Ann [Vis alle 9 forfattere av denne artikkelen] (2020). Divergent relationship between brain structure and cognitive functioning in patients with prominent negative symptomatology. Psychiatry Research : Neuroimaging. ISSN 0925-4927. doi: 10.1016/j.pscychresns.2020.111233. Fulltekst i vitenarkiv
  • Kolskår, Knut-Kristian; Richard, Geneviève; Alnæs, Dag; Dørum, Erlend Solberg; Sanders, Anne-Marthe & Ulrichsen, Kristine Moe [Vis alle 10 forfattere av denne artikkelen] (2020). Reliability, sensitivity, and predictive value of fMRI during multiple object tracking as a marker of cognitive training gain in combination with tDCS in stroke survivors. Human Brain Mapping. ISSN 1065-9471. doi: 10.1002/hbm.25284. Fulltekst i vitenarkiv
  • Ching, Christopher R. K.; Hibar, Derrek P.; Gurholt, Tiril Pedersen; Nunes, Abraham; Thomopoulos, Sophia I. & Abé, Chritsoph [Vis alle 51 forfattere av denne artikkelen] (2020). What we learn about bipolar disorder from large-scale neuroimaging: Findings and future directions from the ENIGMA Bipolar Disorder Working Group. Human Brain Mapping. ISSN 1065-9471. doi: 10.1002/hbm.25098. Fulltekst i vitenarkiv
  • Haukvik, Unn Kristin H.; Gurholt, Tiril Pedersen; Nerland, Stener; Elvsåshagen, Torbjørn; Akudjedu, Theophilus N. & Alda, Martin [Vis alle 97 forfattere av denne artikkelen] (2020). In vivo hippocampal subfield volumes in bipolar disorder—A mega‐analysis from The Enhancing Neuro Imaging Genetics through Meta‐Analysis Bipolar Disorder Working Group. Human Brain Mapping. ISSN 1065-9471. s. 1–14. doi: 10.1002/hbm.25249. Fulltekst i vitenarkiv
  • Rokicki, Jaroslav; Wolfers, Thomas; Nordhøy, Wibeke; Tesli, Natalia; Quintana, Daniel & Alnæs, Dag [Vis alle 20 forfattere av denne artikkelen] (2020). Multimodal imaging improves brain age prediction and reveals distinct abnormalities in patients with psychiatric and neurological disorders. Human Brain Mapping. ISSN 1065-9471. 42(6), s. 1714–1726. doi: 10.1002/hbm.25323. Fulltekst i vitenarkiv
  • Elvsåshagen, Torbjørn; Bahrami, Shahram; van der Meer, Dennis; Agartz, Ingrid; Alnæs, Dag & Barch, Deanna M. [Vis alle 76 forfattere av denne artikkelen] (2020). The genetic architecture of human brainstem structures and their involvement in common brain disorders. Nature Communications. ISSN 2041-1723. 11. doi: 10.1038/s41467-020-17376-1. Fulltekst i vitenarkiv
  • Ulrichsen, Kristine Moe; Alnæs, Dag; Kolskår, Knut-Kristian; Richard, Geneviève; Sanders, Anne-Marthe & Dørum, Erlend Solberg [Vis alle 11 forfattere av denne artikkelen] (2020). Dissecting the cognitive phenotype of post-stroke fatigue using computerized assessment and computational modeling of sustained attention. European Journal of Neuroscience. ISSN 0953-816X. 52(7), s. 3828–3845. doi: 10.1111/ejn.14861. Fulltekst i vitenarkiv
  • Richard, Geneviève; Petersen, Anders; Ulrichsen, Kristine Moe; Kolskår, Knut-Kristian; Alnæs, Dag & Sanders, Anne-Marthe [Vis alle 10 forfattere av denne artikkelen] (2020). TVA-based modeling of short-term memory capacity, speed of processing and perceptual threshold in chronic stroke patients undergoing cognitive training: Case-control differences, reliability, and associations with cognitive performance. PeerJ. ISSN 2167-8359. 8:e9948, s. 1–21. doi: 10.7717/peerj.9948. Fulltekst i vitenarkiv
  • Còrdova Palomera, Aldo; van der Meer, Dennis; Kaufmann, Tobias; Bettella, Francesco; Wang, Yunpeng & Alnæs, Dag [Vis alle 40 forfattere av denne artikkelen] (2020). Genetic control of variability in subcortical and intracranial volumes. Molecular Psychiatry. ISSN 1359-4184. s. 1–8. doi: 10.1038/s41380-020-0664-1. Fulltekst i vitenarkiv
  • Norbom, Linn Christin Bonaventure; Rokicki, Jaroslav; van der Meer, Dennis; Alnæs, Dag; Doan, Nhat Trung & Moberget, Torgeir [Vis alle 10 forfattere av denne artikkelen] (2020). Testing relationships between multimodal modes of brain structural variation and age, sex and polygenic scores for neuroticism in children and adolescents. Translational Psychiatry. ISSN 2158-3188. 10(251). doi: 10.1038/s41398-020-00931-1. Fulltekst i vitenarkiv
  • Norbom, Linn Christin Bonaventure; Rokicki, Jaroslav; Alnæs, Dag; Kaufmann, Tobias; Doan, Nhat Trung & Andreassen, Ole Andreas [Vis alle 8 forfattere av denne artikkelen] (2020). Maturation of cortical microstructure and cognitive development in childhood and adolescence: A T1w/T2w ratio MRI study. Human Brain Mapping. ISSN 1065-9471. 41(16), s. 4676–4690. doi: 10.1002/hbm.25149. Fulltekst i vitenarkiv
  • Tønnesen, Siren; Kaufmann, Tobias; de Lange, Ann-Marie Glasø; Richard, Geneviève; Doan, Nhat Trung & Alnæs, Dag [Vis alle 33 forfattere av denne artikkelen] (2020). Brain age prediction reveals aberrant brain white matter in schizophrenia and bipolar disorder: A multisample diffusion tensor imaging study. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. ISSN 2451-9022. 5(12), s. 1095–1103. doi: 10.1016/j.bpsc.2020.06.014. Fulltekst i vitenarkiv
  • Lund, Martina Jonette; Alnæs, Dag; Schwab, Simon; van der Meer, Dennis; Andreassen, Ole Andreas & Westlye, Lars Tjelta [Vis alle 7 forfattere av denne artikkelen] (2020). Differences in directed functional brain connectivity related to age, sex and mental health. Human Brain Mapping. ISSN 1065-9471. 41(15), s. 4173–4186. doi: 10.1002/hbm.25116. Fulltekst i vitenarkiv
  • Richard, Geneviève; Kolskår, Knut-Kristian; Ulrichsen, Kristine Moe; Kaufmann, Tobias; Alnæs, Dag & Sanders, Anne-Marthe [Vis alle 12 forfattere av denne artikkelen] (2019). Brain age prediction in stroke patients: Highly reliable but limited sensitivity to cognitive performance and response to cognitive training. NeuroImage: Clinical. ISSN 2213-1582. 25, s. 1–11. doi: 10.1016/j.nicl.2019.102159. Fulltekst i vitenarkiv
  • de Lange, Ann-Marie Glasø; Kaufmann, Tobias; van der Meer, Dennis; Maglanoc, Luigi Angelo; Alnæs, Dag & Moberget, Torgeir [Vis alle 9 forfattere av denne artikkelen] (2019). Population-based neuroimaging reveals traces of childbirth in the maternal brain. Proceedings of the National Academy of Sciences of the United States of America. ISSN 0027-8424. 116(44), s. 22341–22346. doi: 10.1073/pnas.1910666116.
  • Alnæs, Dag; Kaufmann, Tobias; van der Meer, Dennis; Còrdova Palomera, Aldo; Rokicki, Jaroslav & Moberget, Torgeir [Vis alle 30 forfattere av denne artikkelen] (2019). Brain heterogeneity in schizophrenia and its association with polygenic risk. JAMA psychiatry. ISSN 2168-6238. 76(7), s. 739–748. doi: 10.1001/jamapsychiatry.2019.0257.
  • Juvodden, Hilde Therese; Alnæs, Dag; Lund, Martina Jonette; Dietrichs, Espen; Thorsby, Per Medbøe & Westlye, Lars Tjelta [Vis alle 7 forfattere av denne artikkelen] (2019). Hypocretin-deficient narcolepsy patients have abnormal brain activation during humor processing. Sleep. ISSN 0161-8105. 42:zsz082(7), s. 1–12. doi: 10.1093/sleep/zsz082. Fulltekst i vitenarkiv
  • Kaufmann, Tobias; van der Meer, Dennis; Doan, Nhat Trung; Schwarz, Emanuel; Lund, Martina Jonette & Agartz, Ingrid [Vis alle 84 forfattere av denne artikkelen] (2019). Common brain disorders are associated with heritable patterns of apparent aging of the brain. Nature Neuroscience. ISSN 1097-6256. 22(10), s. 1617–1623. doi: 10.1038/s41593-019-0471-7. Fulltekst i vitenarkiv
  • Moberget, Torgeir; Alnæs, Dag; Kaufmann, Tobias; Doan, Nhat Trung; Còrdova Palomera, Aldo & Norbom, Linn Christin Bonaventure [Vis alle 10 forfattere av denne artikkelen] (2019). Cerebellar Gray Matter Volume Is Associated With Cognitive Function and Psychopathology in Adolescence. Biological Psychiatry. ISSN 0006-3223. 86(1), s. 65–75. doi: 10.1016/j.biopsych.2019.01.019. Fulltekst i vitenarkiv
  • Quintana, Daniel; Rokicki, Jaroslav; van der Meer, Dennis; Alnæs, Dag; Kaufmann, Tobias & Còrdova Palomera, Aldo [Vis alle 9 forfattere av denne artikkelen] (2019). Oxytocin pathway gene networks in the human brain. Nature Communications. ISSN 2041-1723. 10(1). doi: 10.1038/s41467-019-08503-8. Fulltekst i vitenarkiv
  • Maximov, Ivan; Alnæs, Dag & Westlye, Lars Tjelta (2019). Towards an optimised processing pipeline for diffusion magnetic resonance imaging data: Effects of artefact corrections on diffusion metrics and their age associations in UK Biobank. Human Brain Mapping. ISSN 1065-9471. 40, s. 4146–4162. doi: 10.1002/hbm.24691. Fulltekst i vitenarkiv
  • Høgestøl, Einar August; Nygaard, Gro Owren; Alnæs, Dag; Beyer, Mona K.; Westlye, Lars Tjelta & Harbo, Hanne Flinstad (2019). Symptoms of fatigue and depression is reflected in altered default mode network connectivity in multiple sclerosis. PLOS ONE. ISSN 1932-6203. 14(4). doi: 10.1371/journal.pone.0210375. Fulltekst i vitenarkiv
  • Richard, Geneviève; Kolskår, Knut-Kristian; Sanders, Anne-Marthe; Kaufmann, Tobias; Petersen, Anders & Doan, Nhat Trung [Vis alle 13 forfattere av denne artikkelen] (2018). Assessing distinct patterns of cognitive aging using tissue-specific brain age prediction based on diffusion tensor imaging and brain morphometry. PeerJ. ISSN 2167-8359. doi: 10.7717/peerj.5908. Fulltekst i vitenarkiv
  • Kaufmann, Tobias; Alnæs, Dag; Brandt, Christine Lycke; Bettella, Francesco; Djurovic, Srdjan & Andreassen, Ole Andreas [Vis alle 7 forfattere av denne artikkelen] (2018). Stability of the Brain Functional Connectome Fingerprint in Individuals With Schizophrenia. JAMA psychiatry. ISSN 2168-6238. doi: 10.1001/jamapsychiatry.2018.0844.
  • Quintana, Daniel; Westlye, Lars Tjelta; Alnæs, Dag; Kaufmann, Tobias; Mahmoud, Ramy A. & Smerud, Knut Terje [Vis alle 8 forfattere av denne artikkelen] (2018). Low-dose intranasal oxytocin delivered with Breath Powered device modulates pupil diameter and amygdala activity: a randomized controlled pupillometry and fMRI study. Neuropsychopharmacology. ISSN 0893-133X. 44, s. 306–313. doi: 10.1038/s41386-018-0241-3.
  • Norbom, Linn Christin Bonaventure; Doan, Nhat Trung; Alnæs, Dag; Kaufmann, Tobias; Moberget, Torgeir & Rokicki, Jaroslav [Vis alle 9 forfattere av denne artikkelen] (2018). Probing brain developmental patterns of myelination and associations with psychopathology in youths using gray/white matter contrast. Biological Psychiatry. ISSN 0006-3223. doi: 10.1016/j.biopsych.2018.09.027. Fulltekst i vitenarkiv
  • Wolfers, Thomas; Doan, Nhat Trung; Kaufmann, Tobias; Alnæs, Dag; Moberget, Torgeir & Agartz, Ingrid [Vis alle 14 forfattere av denne artikkelen] (2018). Mapping the heterogeneous phenotype of schizophrenia and bipolar disorder using normative models. JAMA psychiatry. ISSN 2168-6238. 75(11), s. 1146–1155. doi: 10.1001/jamapsychiatry.2018.2467.
  • Juvodden, Hilde Therese; Alnæs, Dag; Lund, Martina Jonette; Agartz, Ingrid; Andreassen, Ole Andreas & Dietrichs, Espen [Vis alle 9 forfattere av denne artikkelen] (2018). Widespread white matter changes in post-H1N1 patients with narcolepsy type 1 and first-degree relatives. Sleep. ISSN 0161-8105. 41(10). doi: 10.1093/sleep/zsy145. Fulltekst i vitenarkiv
  • van der Meer, Dennis; Rokicki, Jaroslav; Kaufmann, Tobias; Còrdova Palomera, Aldo; Moberget, Torgeir & Alnæs, Dag [Vis alle 54 forfattere av denne artikkelen] (2018). Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes. Molecular Psychiatry. ISSN 1359-4184. s. 1–13. doi: 10.1038/s41380-018-0262-7. Fulltekst i vitenarkiv
  • Nunes, Abraham; Schnack, Hugo G.; Ching, Christopher R.K.; Agartz, Ingrid; Akudjedu, Theophilus N. & Alda, Martin [Vis alle 74 forfattere av denne artikkelen] (2018). Using structural MRI to identify bipolar disorders ? 13 site machine learning study in 3020 individuals from the ENIGMA Bipolar Disorders Working Group. Molecular Psychiatry. ISSN 1359-4184. doi: 10.1038/s41380-018-0228-9. Fulltekst i vitenarkiv
  • Kolskår, Knut-Kristian; Alnæs, Dag; Kaufmann, Tobias; Richard, Geneviéve´; Sanders, Anne-Marthe & Ulrichsen, Kristine Moe [Vis alle 10 forfattere av denne artikkelen] (2018). Key Brain Network Nodes Show Differential Cognitive Relevance and Developmental Trajectories during Childhood and Adolescence. eNeuro. ISSN 2373-2822. 5(4), s. 1–13. doi: 10.1523/ENEURO.0092-18.2018. Fulltekst i vitenarkiv
  • Tønnesen, Siren; Kaufmann, Tobias; Doan, Nhat Trung; Alnæs, Dag; Còrdova Palomera, Aldo & van der Meer, Dennis [Vis alle 15 forfattere av denne artikkelen] (2018). White matter aberrations and age-related trajectories in patients with schizophrenia and bipolar disorder revealed by diffusion tensor imaging . Scientific Reports. ISSN 2045-2322. 8. doi: 10.1038/s41598-018-32355-9. Fulltekst i vitenarkiv
  • Còrdova Palomera, Aldo; Kaufmann, Tobias; Bettella, Francesco; Wang, Yunpeng; Doan, Nhat Trung & van der Meer, Dennis [Vis alle 12 forfattere av denne artikkelen] (2018). Effects of autozygosity and schizophrenia polygenic risk on cognitive and brain developmental trajectories. European Journal of Human Genetics. ISSN 1018-4813. 26(7), s. 1049–1059. doi: 10.1038/s41431-018-0134-2.
  • Alnæs, Dag; Kaufmann, Tobias; Doan, Nhat Trung; Còrdova Palomera, Aldo; Wang, Yunpeng & Bettella, Francesco [Vis alle 9 forfattere av denne artikkelen] (2018). Association of Heritable Cognitive Ability and Psychopathology With White Matter Properties in Children and Adolescents. JAMA psychiatry. ISSN 2168-6238. 75(3), s. 287–295. doi: 10.1001/jamapsychiatry.2017.4277.
  • Moberget, Torgeir; Doan, Nhat Trung; Alnæs, Dag; Kaufmann, Tobias; Còrdova Palomera, Aldo & Lagerberg, Trine Vik [Vis alle 22 forfattere av denne artikkelen] (2017). Cerebellar volume and cerebellocerebral structural covariance in schizophrenia: a multisite mega-analysis of 983 patients and 1349 healthy controls. Molecular Psychiatry. ISSN 1359-4184. 23(6), s. 1512–1520. doi: 10.1038/mp.2017.106.
  • Elvsåshagen, Torbjørn; Zak, Nathalia; Norbom, Linn Christin Bonaventure; Pedersen, Per Øystein Heiberg; Quraishi, Sophia H. & Bjørnerud, Atle [Vis alle 11 forfattere av denne artikkelen] (2017). Evidence for cortical structural plasticity in humans after a day of waking and sleep deprivation. NeuroImage. ISSN 1053-8119. 156, s. 214–223. doi: 10.1016/j.neuroimage.2017.05.027. Fulltekst i vitenarkiv
  • Doan, Nhat Trung; Kaufmann, Tobias; Bettella, Francesco; Jørgensen, Kjetil Nordbø; Brandt, Christine Lycke & Moberget, Torgeir [Vis alle 15 forfattere av denne artikkelen] (2017). Distinct multivariate brain morphological patterns and their added predictive value with cognitive and polygenic risk scores in mental disorders. NeuroImage: Clinical. ISSN 2213-1582. 15, s. 719–731. doi: 10.1016/j.nicl.2017.06.014. Fulltekst i vitenarkiv
  • Skåtun, Kristina Cecilie; Kaufmann, Tobias; Brandt, Christine Lycke; Doan, Nhat Trung; Alnæs, Dag & Tønnesen, Siren [Vis alle 12 forfattere av denne artikkelen] (2017). Thalamo-cortical functional connectivity in schizophrenia and bipolar disorder. Brain Imaging and Behavior. ISSN 1931-7557. doi: 10.1007/s11682-017-9714-y.
  • Doan, Nhat Trung; Engvig, Andreas; Zaske, Krystal; Persson, Karin; Lund, Martina Jonette & Kaufmann, Tobias [Vis alle 17 forfattere av denne artikkelen] (2017). Distinguishing early and late brain aging from the Alzheimer's disease spectrum: Consistent morphological patterns across independent samples. NeuroImage. ISSN 1053-8119. 158, s. 282–295. doi: 10.1016/j.neuroimage.2017.06.070. Fulltekst i vitenarkiv
  • Kaufmann, Tobias; Alnæs, Dag; Doan, Nhat Trung; Brandt, Christine Lycke; Andreassen, Ole Andreas & Westlye, Lars Tjelta (2017). Delayed stabilization and individualization in connectome development are related to psychiatric disorders. Nature Neuroscience. ISSN 1097-6256. 20(4), s. 513–515. doi: 10.1038/nn.4511.
  • Mowinckel, Athanasia Monika; Alnæs, Dag; Pedersen, Mads Lund; Ziegler, Sigurd; Fredriksen, Mats & Kaufmann, Tobias [Vis alle 10 forfattere av denne artikkelen] (2017). Increased default-mode variability is related to reduced task-performance and is evident in adults with ADHD. NeuroImage: Clinical. ISSN 2213-1582. 16, s. 369–382. doi: 10.1016/j.nicl.2017.03.008. Fulltekst i vitenarkiv
  • Doan, Nhat Trung; Engvig, Andreas; Persson, Karin; Alnæs, Dag; Kaufmann, Tobias & Rokicki, Jaroslav [Vis alle 14 forfattere av denne artikkelen] (2017). Dissociable diffusion MRI patterns of white matter microstructure and connectivity in Alzheimer's disease spectrum. Scientific Reports. ISSN 2045-2322. 7:45131. doi: 10.1038/srep45131.
  • Westlye, Lars Tjelta; Kaufmann, Tobias; Alnæs, Dag; Hullstein, Ingunn Riise & Bjørnebekk, Astrid (2017). Brain connectivity aberrations in anabolic-androgenic steroid users. NeuroImage: Clinical. ISSN 2213-1582. 13, s. 62–69. doi: 10.1016/j.nicl.2016.11.014.
  • Dørum, Erlend Solberg; Kaufmann, Tobias; Alnæs, Dag; Andreassen, Ole Andreas; Richard, Geneviéve´ & Kolskår, Knut-Kristian [Vis alle 8 forfattere av denne artikkelen] (2017). Increased sensitivity to age-related differences in brain functional connectivity during continuous multiple object tracking compared to resting-state. NeuroImage. ISSN 1053-8119. 148, s. 364–372. doi: 10.1016/j.neuroimage.2017.01.048.
  • Kaufmann, Tobias; Alnæs, Dag; Brandt, Christine Lycke; Doan, Nhat Trung; Kauppi, Karolina & Bettella, Francesco [Vis alle 14 forfattere av denne artikkelen] (2017). Task modulations and clinical manifestations in the brain functional connectome in 1615 fMRI datasets. NeuroImage. ISSN 1053-8119. 147, s. 243–252. doi: 10.1016/j.neuroimage.2016.11.073.
  • Còrdova Palomera, Aldo; Kaufmann, Tobias; Persson, Karin; Alnæs, Dag; Doan, Nhat Trung & Moberget, Torgeir [Vis alle 14 forfattere av denne artikkelen] (2017). Disrupted global metastability and static and dynamic brain connectivity across individuals in the Alzheimer's disease continuum. Scientific Reports. ISSN 2045-2322. 7(40268), s. 1–14. doi: 10.1038/srep40268. Fulltekst i vitenarkiv
  • Skåtun, Kristina Cecilie; Kaufmann, Tobias; Doan, Nhat Trung; Alnæs, Dag; Còrdova Palomera, Aldo & Jönsson, Erik Gunnar [Vis alle 12 forfattere av denne artikkelen] (2016). Consistent functional connectivity alterations in schizophrenia spectrum disorder: a multisite study. Schizophrenia Bulletin. ISSN 0586-7614. 43(4), s. 914–924. doi: 10.1093/schbul/sbw145.
  • Haatveit, Beathe Christin; Jensen, Jimmy; Alnæs, Dag; Kaufmann, Tobias; Brandt, Christine Lycke & Thoresen, Christian [Vis alle 10 forfattere av denne artikkelen] (2016). Reduced load-dependent default mode network deactivation across executive tasks in schizophrenia spectrum disorders. NeuroImage: Clinical. ISSN 2213-1582. 12, s. 389–396. doi: 10.1016/j.nicl.2016.08.012.
  • Dørum, Erlend Solberg; Alnæs, Dag; Kaufmann, Tobias; Richard, Geneviéve´; Lund, Martina Jonette & Tønnesen, Siren [Vis alle 15 forfattere av denne artikkelen] (2016). Age-related differences in brain network activation and co-activation during multiple object tracking. Brain and Behavior. ISSN 2162-3279. 6(11). doi: 10.1002/brb3.533. Fulltekst i vitenarkiv
  • Ulrichsen, Kristine Moe; Kaufmann, Tobias; Dørum, Erlend Solberg; Kolskår, Knut-Kristian; Richard, Geneviéve´ & Alnæs, Dag [Vis alle 9 forfattere av denne artikkelen] (2016). Clinical utility of mindfulness training in the treatment of fatigue after stroke, traumatic brain injury and multiple sclerosis: A systematic literature review and meta-analysis. Frontiers in Psychology. ISSN 1664-1078. 7. doi: 10.3389/fpsyg.2016.00912. Fulltekst i vitenarkiv
  • Quintana, Daniel; Westlye, Lars Tjelta; Alnæs, Dag; Rustan, Øyvind; Kaufmann, Tobias & Smerud, Knut Terje [Vis alle 9 forfattere av denne artikkelen] (2016). Low dose intranasal oxytocin delivered with Breath Powered device dampens amygdala response to emotional stimuli: A peripheral effect-controlled within- subjects randomized dose-response fMRI trial. Psychoneuroendocrinology. ISSN 0306-4530. 69, s. 180–188. doi: 10.1016/j.psyneuen.2016.04.010. Fulltekst i vitenarkiv
  • Roe, James; Nesheim, Mathias; Mathiesen, Nina Chung; Moberget, Torgeir; Alnæs, Dag & Sneve, Markus Handal (2016). The effects of tDCS upon sustained visual attention are dependent on cognitive load. Neuropsychologia. ISSN 0028-3932. 80, s. 1–8. doi: 10.1016/j.neuropsychologia.2015.11.005.
  • Skåtun, Kristina Cecilie; Kaufmann, Tobias; Tønnesen, Siren; Biele, Guido; Melle, Ingrid & Agartz, Ingrid [Vis alle 9 forfattere av denne artikkelen] (2016). Global brain connectivity alterations in persons with schizophrenia and bipolar spectrum disorders. Journal of Psychiatry & Neuroscience. ISSN 1180-4882. 41(5), s. 331–341. doi: 10.1503/jpn.150159. Fulltekst i vitenarkiv
  • Kaufmann, Tobias; Elvsåshagen, Torbjørn; Alnæs, Dag; Zak, Nathalia; Pedersen, Per Øystein Heiberg & Norbom, Linn Christin Bonaventure [Vis alle 17 forfattere av denne artikkelen] (2015). The brain functional connectome is robustly altered by lack of sleep. NeuroImage. ISSN 1053-8119. 127, s. 324–332. doi: 10.1016/j.neuroimage.2015.12.028.
  • Alnæs, Dag; Sneve, Markus Handal; Richard, Geneviéve´; Skåtun, Kristina Cecilie; Kaufmann, Tobias & Nordvik, Jan Egil [Vis alle 10 forfattere av denne artikkelen] (2015). Functional connectivity indicates differential roles for the intraparietal sulcus and the superior parietal lobule in multiple object tracking. NeuroImage. ISSN 1053-8119. 123, s. 129–137. doi: 10.1016/j.neuroimage.2015.08.029.
  • Kaufmann, Tobias; Skåtun, Kristina Cecilie; Alnæs, Dag; Doan, Nhat Trung; Duff, Eugene & Tønnesen, Siren [Vis alle 15 forfattere av denne artikkelen] (2015). Disintegration of sensorimotor brain networks in schizophrenia. Schizophrenia Bulletin. ISSN 0586-7614. 41(6), s. 1326–1335. doi: 10.1093/schbul/sbv060.
  • Alnæs, Dag; Kaufmann, Tobias; Richard, Geneviéve´; Duff, Eugene; Sneve, Markus Handal & Endestad, Tor [Vis alle 10 forfattere av denne artikkelen] (2015). Attentional load modulates large-scale functional brain connectivity beyond the core attention networks. NeuroImage. ISSN 1053-8119. 109, s. 260–272. doi: 10.1016/j.neuroimage.2015.01.026.
  • Sneve, Markus Handal; Sreenivasan, Kartik K; Alnæs, Dag; Endestad, Tor & Magnussen, Svein (2015). Short-term retention of visual information: Evidence in support of feature-based attention as an underlying mechanism. Neuropsychologia. ISSN 0028-3932. 66, s. 1–9. doi: 10.1016/j.neuropsychologia.2014.11.004.

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  • Voldsbekk, Irene; Lund, Martina Jonette; Kaufmann, Tobias; Fernandez-Cabello, Sara; Kjelkenes, Rikka & Dahl, Andreas [Vis alle 9 forfattere av denne artikkelen] (2022). Cross-Diagnostic Patterns of Socio-Cognitive Traits in the Developing Brain of Children and Adolescents.
  • Kaufmann, Tobias; van der Meer, Dennis; Doan, Nhat Trung; Schwarz, Emanuel; Lund, Martina Jonette & Agartz, Ingrid [Vis alle 97 forfattere av denne artikkelen] (2020). Publisher Correction: Common brain disorders are associated with heritable patterns of apparent aging of the brain (Nature Neuroscience, (2019), 22, 10, (1617-1623), 10.1038/s41593-019-0471-7). Nature Neuroscience. ISSN 1097-6256. 23(2). doi: 10.1038/s41593-019-0553-6.
  • Alnæs, Dag & Westlye, Lars Tjelta (2019). Factors Associated with Brain Heterogeneity in Schizophrenia - Reply. JAMA psychiatry. ISSN 2168-6238. 76(11), s. 1211–1212. doi: 10.1001/jamapsychiatry.2019.1855.
  • Laeng, Bruno & Alnæs, Dag (2019). Pupillometry. I Klein, Christoph & Ettinger, Ulrich (Red.), Eye Movement Research. Springer Nature. ISSN 978-3-030-20083-1. s. 449–502. doi: 10.1007/978-3-030-20085-5_11.
  • Córdova-Palomera, Aldo; Bettella, Francesco; Wang, Yunpeng; Doan, Nhat Trung; Alnæs, Dag & Moberget, Torgeir [Vis alle 11 forfattere av denne artikkelen] (2016). POTENTIAL BRAIN MORPHOLOGY INSTABILITY FEATURES MEDIATING THE ASSOCIATION BETWEEN GENOME-WIDE HOMOZYGOSITY AND ALTERED NEUROCOGNITION.
  • Nilsen, Andre Sevenius; Endestad, Tor & Alnæs, Dag (2014). Right Inferior Frontal Gyrus and Motor Response Inhibition A Real-Time FMRI Neurofeedback Study. Universitetet i Oslo.

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Publisert 27. okt. 2016 12:47 - Sist endret 27. juni 2019 10:00