Hanna Chan

Doctoral Research Fellow - Molecular Immunology
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Room 2361
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Visiting address Domus Medica Sognsvannsveien 9 0372 Oslo
Postal address Postboks 1105 Blindern 0317 Oslo
Other affiliations Faculty of Medicine (Student)

Academic interests

  • Molecular immunology
  • T cell activation and signalling
  • Cancer immunotherapy

Background

  • 2018-present: Doctoral research fellow in molecular immunology
  • 2017-2018: MSc Immunology, Imperial College London, UK - MSc thesis: “The Role of DYRK1A in B Cell Survival” at The Francis Crick Institute
  • 2012-2016: BSc Biological Sciences, Nanyang Technological University, Singapore - BSc thesis: "Impact of Cutaneous Dendritic Cell Subsets on the Evolution of Lymphoid Cells in Response to Propionibacterium acnes" at Singapore Immunology Network

Publications

  • Borowicz, Pawel; Chan, Hanna; Hauge, Anette & Spurkland, Anne (2020). Adaptor proteins: Flexible and dynamic modulators of immune cell signalling. Scandinavian Journal of Immunology.  ISSN 0300-9475.  92(6) . doi: 10.1111/sji.12951 Full text in Research Archive. Show summary
  • Borowicz, Pawel; Chan, Hanna; Talmo Medina, Daniel; Gumpelmair, Simon; Kjelstrup, Hanna & Spurkland, Anne (2019). A simple and efficient workflow for generation of knock-in mutations in Jurkat T cells using CRISPR/Cas9. Scandinavian Journal of Immunology.  ISSN 0300-9475. . doi: 10.1111/sji.12862 Full text in Research Archive.
  • Borowicz, Pawel; Gopalakrishnan, Ramakrishna Prabhu; Chan, Hanna; Kjelstrup, Hanna; Foss, Stian; De Souza, Gustavo Antonio; Sundvold-Gjerstad, Vibeke & Spurkland, Anne (2019). A conserved pTyr motif in the unstructured C-terminus regulates the function of the T cell specific adaptor TSAd.
  • Borowicz, Pawel; Sundvold-Gjerstad, Vibeke; Chan, Hanna; Abrahamsen, Greger; Kjelstrup, Hanna; Medina, Daniel; Nyman, Tuula Anneli & Spurkland, Anne (2019). Tyr192 in the Lck SH2 domain affects the regulation of Lck activity.
Published Dec. 19, 2018 7:55 PM - Last modified Dec. 19, 2020 1:39 PM