Trygve Brauns Leergaard

Professor - Neural Systems
Image of Trygve Brauns Leergaard
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Phone +47-22851052
Room L-169
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Visiting address Dept. of Anatomy Gaustad Domus Medica 0372 Oslo Sognsvannsveien 9
Postal address Postboks 1105 Blindern 0317 OSLO

Academic interests

  • Neuroanatomy, brain connectivity mapping
  • Morphological phenotyping
  • Neuroinformatics and digital brain atlasing
  • Histological validation of neuroimaging methods

Courses taught

MEDSEM3A – macroscopic anatomy

Background

  • MD, University of Leiden, The Netherlands, 1996
  • PhD, University of Oslo, Neuroscience, 2000

Work experience

  • 2006- : Deputy group leader, Neural Systems and Graphics Computing Laboratory, Experimental Division, Institute of Basic Medical Sciences, University of Oslo
  • 2004- : Deputy associate professor, Department of anatomy, Institute of Basic Medical Sciences, University of Oslo
  • 2002-2003: Research fellow, Department of Radiology, Massachusetts General Hospital, Nuclear Magnetic Resonance Center, Harvard Medical School, Boston, USA
  • 2001-2003: Postdoc fellow, Department of  Anatomy, Institute of Basic Medical Sciences, University of Oslo

Positions held

  • Guest Associate Editor, Frontiers in Neuroinformatics (2010-2011)
  • Member semester board (semesterutvalg) MEDSEM3A (2008- ), Faculty of Medicine, University of Oslo
  • Member advisory board (programrådet), The Faculty of Medicine, University of Oslo (2009- )
  • Key advisor for high throughput tissue processing unit at the Institute of Basic Medical Sciences, University of Oslo

Collaboration

  • Anders M. Dale, University of California, San Diego, USA
  • G. Allan Johnson, Center for In Vivo Microscopy, Duke University Medical Center, USA
  • Annemie Van der Linden, Bio-Imaging lab, University of Antwerp, Belgium
  • Stephan von Hörsten, Experimental Therapy, Friedrich-Alexander University, Erlangen, Germany
  • Jan Sijbers, Vision Lab, Department of Physics, University of Antwerp, Belgium
  • Menno P. Witter, The Kavli Institute for Systems Neuroscience & Centre for the Biology of Memory, Norwegian University of Science and Technology (NTNU), Trondheim
Tags: Cerebellum, Neuroanatomy, Brain and nervous system, Basal ganglia, Vasculature and lungs, Neurodegenerative disease models, Diagnostic imaging and intervention, Heart

Publications

  • Bjerke, Ingvild Elise; Øvsthus, Martin; Papp, Eszter Agnes; Yates, Sharon Christine; Silvestri, L; Fiorilli, J; Pennartz, CMA; Pavone, FS; Puchades, Maja; Leergaard, Trygve Brauns & Bjaalie, Jan G. (2018). Data integration through brain atlasing: Human Brain Project tools and strategies. European psychiatry.  ISSN 0924-9338.  50, s 70- 76 . doi: 10.1016/j.eurpsy.2018.02.0
  • Mughal, Awais; Zhang, Lili; Fayzullin, Artem; Server, Andrés; Li, Yuping; Wu, Yingxi; Glass, Rainer; Meling, Torstein Ragnar; Langmoen, Iver Arne; Leergaard, Trygve Brauns & Vik-Mo, Einar O. (2018). Patterns of Invasive Growth in Malignant Gliomas - The Hippocampus Emerges as an Invasion-Spared Brain Region. Neoplasia.  ISSN 1522-8002.  20(7), s 643- 656 . doi: 10.1016/j.neo.2018.04.001
  • Stahl, Katja; Rahmani, Soulmaz; Prydz, Agnete; Skauli, Nadia; MacAulay, Nanna; Mylonakou, Maria-Niki; Torp, Reidun; Skare, Øivind; Berg, Torill; Leergaard, Trygve Brauns; Paulsen, Ragnhild Elisabeth; Ottersen, Ole Petter & Amiry-Moghaddam, Mahmood (2018). Targeted deletion of the aquaglyceroporin AQP9 is protective in a mouse model of Parkinson's disease. PLoS ONE.  ISSN 1932-6203.  13(3) . doi: 10.1371/journal.pone.0194896
  • Blackstad, Jan Sigurd Beddari; Osen, Kirsten Kjelsberg; Scharfman, Helen E.; Storm-Mathisen, Jon; Blackstad, Theodor & Leergaard, Trygve Brauns (2016). Observations on hippocampal mossy cells in mink (Neovison vison) with special reference to dendrites ascending to the granular and molecular layers. Hippocampus.  ISSN 1050-9631.  26(2), s 229- 245 . doi: 10.1002/hipo.22518
  • Papp, Eszter Agnes; Leergaard, Trygve Brauns; Csúcs, Gergely & Bjaalie, Jan G. (2016). Brain-wide mapping of axonal connections: Workflow for automated detection and spatial analysis of labeling in microscopic sections. Frontiers in Neuroinformatics.  ISSN 1662-5196.  10(11) . doi: 10.3389/fninf.2016.00011 Full text in Research Archive.
  • Schubert, N; Axer, M; Schober, M; Huynh, A; Huysegoms, M; Palomero-Gallagher, N; Bjaalie, Jan G.; Leergaard, Trygve Brauns; Kirlangic, Mehmet E.; Amunts, K & Zilles, Karl (2016). 3D reconstructed cyto-, muscarinic M<sub>2</sub> receptor, and fiber architecture of the rat brain registered to the waxholm space atlas. Frontiers in Neuroanatomy.  ISSN 1662-5129.  10(MAY) . doi: 10.3389/fnana.2016.00051
  • Yetman, Michael J.; Lillehaug, Sveinung; Bjaalie, Jan G.; Leergaard, Trygve Brauns & Jankowsky, Joanna L. (2016). Transgene expression in the Nop-tTA driver line is not inherently restricted to the entorhinal cortex. Brain Structure and Function.  ISSN 1863-2653.  221(4), s 2231- 2249 . doi: 10.1007/s00429-015-1040-9
  • Boccara, Charlotte Nina; Kjønigsen, Lisa Jannicke; Hammer, Ingvild Marie F.; Bjaalie, Jan G.; Leergaard, Trygve Brauns & Witter, Menno (2015). A three-plane architectonic atlas of the rat hippocampal region. Hippocampus.  ISSN 1050-9631.  25(7), s 838- 857 . doi: 10.1002/hipo.22407
  • Kjønigsen, Lisa Jannicke; Lillehaug, Sveinung; Bjaalie, Jan G.; Witter, Menno & Leergaard, Trygve Brauns (2015). Waxholm Space atlas of the rat brain hippocampal region: Three-dimensional delineations based on magnetic resonance and diffusion tensor imaging. NeuroImage.  ISSN 1053-8119.  108, s 441- 449 . doi: 10.1016/j.neuroimage.2014.12.080 Full text in Research Archive.
  • Papp, Eszter Agnes; Leergaard, Trygve Brauns; Calabrese, Evan; Johnson, G. Allan & Bjaalie, Jan G. (2015). Addendum to “Waxholm Space atlas of the Sprague Dawley rat brain” [NeuroImage 97 (2014) 374-386]. NeuroImage.  ISSN 1053-8119.  105, s 561- 562 . doi: 10.1016/j.neuroimage.2014.10.017
  • Vårbakken, Kjartan; Steen, Harald; Samuelsen, Gunnar; Dahl, Hans A; Leergaard, Trygve Brauns & Stuge, Britt (2015). Primary functions of the quadratus femoris and obturator externus muscles indicated from lengths and moment arms measured in mobilized cadavers. Clinical Biomechanics.  ISSN 0268-0033.  30(3), s 231- 237 . doi: 10.1016/j.clinbiomech.2015.02.004
  • Zakiewicz, Izabela Maria; Majka, Piotr; Wòjcik, Daniel K.; Bjaalie, Jan G. & Leergaard, Trygve Brauns (2015). Three-Dimensional Histology Volume Reconstruction of Axonal Tract Tracing Data: Exploring Topographical Organization in Subcortical Projections from Rat Barrel Cortex. PLoS ONE.  ISSN 1932-6203.  10(9) . doi: 10.1371/journal.pone.0137571
  • Lillehaug, Sveinung; Syverstad, Gry-Helen Enger; Nilsson, Lars; Bjaalie, Jan G.; Leergaard, Trygve Brauns & Torp, Reidun (2014). Brainwide distribution and variance of amyloid-beta deposits in tg-ArcSwe mice. Neurobiology of Aging.  ISSN 0197-4580.  35(3), s 556- 564 . doi: 10.1016/j.neurobiolaging.2013.09.013
  • Nuruddin, Syed; Syverstad, Gry-Helen Enger; Lillehaug, Sveinung; Leergaard, Trygve Brauns; Nilsson, Lars; Ropstad, Erik; Krogenæs, Anette; Haraldsen, Ira Hebold & Torp, Reidun (2014). Elevated mRNA-Levels of Gonadotropin-Releasing Hormone and Its Receptor in Plaque-Bearing Alzheimer's Disease Transgenic Mice. PLoS ONE.  ISSN 1932-6203.  9(8) . doi: 10.1371/journal.pone.0103607
  • Pandya, Abhilash D.; Leergaard, Trygve Brauns; Dissen, Erik; Haraldsen, Guttorm & Spurkland, Anne (2014). Expression of the T cell-specific adapter protein in human tissues. Scandinavian Journal of Immunology.  ISSN 0300-9475.  80(3), s 169- 179 . doi: 10.1111/sji.12199
  • Papp, Eszter Agnes; Leergaard, Trygve Brauns; Calabrese, Evan; Johnson, G. Allan & Bjaalie, Jan G. (2014). Waxholm Space atlas of the Sprague Dawley rat brain. NeuroImage.  ISSN 1053-8119.  97, s 374- 386 . doi: 10.1016/j.neuroimage.2014.04.001
  • Vårbakken, Kjartan; Steen, Harald; Samuelsen, Gunnar; Dahl, Hans A; Leergaard, Trygve Brauns; Nordsletten, Lars & Stuge, Britt (2014). Lengths of the external hip rotators in mobilized cadavers indicate the quadriceps coxa as a primary abductor and extensor of the flexed hip. Clinical Biomechanics.  ISSN 0268-0033.  29(7), s 794- 802 . doi: 10.1016/j.clinbiomech.2014.05.011
  • Zakiewicz, Izabela Maria; Bjaalie, Jan G. & Leergaard, Trygve Brauns (2014). Brain-wide map of efferent projections from rat barrel cortex. Frontiers in Neuroinformatics.  ISSN 1662-5196.  8 . doi: 10.3389/fninf.2014.00005
  • Nagelhus, Erlend Arnulf; Amiry-Moghaddam, Mahmood; Bergersen, Linda Hildegard; Bjaalie, Jan G.; Eriksson, Jens; Gundersen, Vidar; Leergaard, Trygve Brauns; Morth, Jens Preben; Storm-Mathisen, Jon; Torp, Reidun; Walhovd, Kristine B & Tønjum, Tone (2013). The glia doctrine: Addressing the role of glial cells in healthy brain ageing. Mechanisms of Ageing and Development.  ISSN 0047-6374.  134(10), s 449- 459 . doi: 10.1016/j.mad.2013.10.001
  • Stensrud, Mats Julius; Chaudhry, Farrukh Abbas; Leergaard, Trygve Brauns; Bjaalie, Jan G. & Gundersen, Vidar (2013). Vesicular glutamate transporter-3 in the rodent brain: Vesicular colocalization with vesicular -aminobutyric acid transporter. Journal of Comparative Neurology.  ISSN 0021-9967.  521(13), s 3042- 3056 . doi: 10.1002/cne.23331
  • White, NS; Leergaard, Trygve Brauns; D'Arceuil, Helen; Bjaalie, Jan G. & Dale, AM (2013). Probing tissue microstructure with Restriction Spectrum Imaging: Histological and theoretical validation. Human Brain Mapping.  ISSN 1065-9471.  34(2), s 327- 346 . doi: 10.1002/hbm.21454
  • Antonsen, Bjørnar Torske; Jiang, Yi; Veraart, Jelle; Qu, Hong; Nguyen, Huu Phuc; Sijbers, Jan; von Hörsten, Stephan; Johnson, G. Allan & Leergaard, Trygve Brauns (2012). Altered diffusion tensor imaging measurements in aged transgenic Huntington disease rats. Brain Structure and Function.  ISSN 1863-2653. . doi: 10.1007/s00429-012-0427-0
  • Blockx, I; Verhoye, M; Van Audekerke, J; Bergwerf, I; Kane, John; Palacios, RDY; Veraart, J; Jeurissen, B; Raber, K; von Horsten, S; Ponsaerts, P; Sijbers, J; Leergaard, Trygve Brauns & Van der Linden, A (2012). Identification and characterization of Huntington related pathology: An in vivo DKI imaging study. NeuroImage.  ISSN 1053-8119.  63(2), s 653- 662 . doi: 10.1016/j.neuroimage.2012.06.032
  • Leergaard, Trygve Brauns; Hilgetag, Claus C & Sporns, Olaf (2012). Mapping the connectome: multi-level analysis of brain connectivity. Frontiers in Neuroinformatics.  ISSN 1662-5196. . doi: 10.3389/fninf.2012.00014
  • Kjønigsen, Lisa Jannicke; Leergaard, Trygve Brauns; Witter, Menno & Bjaalie, Jan G. (2011). Digital atlas of anatomical subdivisions and boundaries of the rat hippocampal region. Frontiers in Neuroinformatics.  ISSN 1662-5196.  8(5) . doi: 10.3389/fninf.2011.00002
  • Odeh, U. R. Francis; Leergaard, Trygve Brauns; Boy, J.; Schmidt, T.; Riess, O. & Bjaalie, Jan G. (2011). Atlas of transgenic Tet-Off Ca2+/calmodulin-dependent protein kinase II and prion protein promoter activity in the mouse brain. NeuroImage.  ISSN 1053-8119.  54(4), s 2603- 2611 . doi: 10.1016/j.neuroimage.2010.11.032
  • Veraart, Jelle; Leergaard, Trygve Brauns; Antonsen, Bjørnar; Van Hecke, Wim; Blockx, Ines; Jeurissen, Ben; Jiang, Yi; Van der Linden, Annemie; Johnson, G. Allan; Verhoye, Marleen & Sijbers, Jan (2011). Population-averaged diffusion tensor imaging atlas of the Sprague Dawley rat brain. NeuroImage.  ISSN 1053-8119.  58(4), s 975- 983 . doi: 10.1016/j.neuroimage.2011.06.063
  • Zakiewicz, Izabela Maria; Van Dongen, Yvette C; Leergaard, Trygve Brauns & Bjaalie, Jan G. (2011). Workflow and Atlas System for Brain-Wide Mapping of Axonal Connectivity in Rat. PLoS ONE.  ISSN 1932-6203.  6(8) . doi: 10.1371/journal.pone.0022669
  • Leergaard, Trygve Brauns; White, Nathan; De Crespigny, Alex; Bolstad, Ingeborg; D'Arceuil, Helen; Bjaalie, Jan G. & Dale, Anders M (2010). Quantitative Histological Validation of Diffusion MRI Fiber Orientation Distributions in the Rat Brain. PLoS ONE.  ISSN 1932-6203.  5(1) . doi: 10.1371/journal.pone.0008595
  • Holmseth, Silvia; Scott, Heather A; Real, Katia; Lehre, Knut Petter Dæhlin; Leergaard, Trygve Brauns; Bjaalie, Jan G. & Danbolt, Niels Christian (2009). The concentrations and distributions of three C-terminal variants of the GLT1 (EAAT2; slc1a2) glutamate transporter protein in rat brain tissue suggest differential regulation. Neuroscience.  ISSN 0306-4522.  162(4), s 1055- 1071 . doi: 10.1016/j.neuroscience.2009.03.048
  • Kjønigsen, Lisa Jannicke; Leergaard, Trygve Brauns; Moene, Ivar Andre; Witter, Menno P & Bjaalie, Jan G. (2009). Interactive atlas of the rat hippocampus integrating high-resolution histological images and boundary definitions. Frontiers in Neuroinformatics.  ISSN 1662-5196. . doi: 10.3389/conf.neuro.11.2009.08.013
  • Zakiewicz, Izabela Maria; Van Dongen, Yvette C; Moene, Ivar Andre; Leergaard, Trygve Brauns & Bjaalie, Jan G. (2009). Towards an interactive digital atlas system for exploring anatomical connectivity patterns in the entire rat brain. Frontiers in Neuroinformatics.  ISSN 1662-5196. . doi: 10.3389/conf.neuro.11.2009.08.014

View all works in Cristin

  • Bjerke, Ingvild Elise; Øvsthus, Martin; Andersson, Krister Andreas; Bjaalie, Jan G. & Leergaard, Trygve B. (2018). Best practices for determining and documenting neuroanatomical locations in the rodent brain.
  • Blixhavn, Camilla Hagen; Andersson, Krister; Øvsthus, Martin; Bjerke, Ingvild Elise; Kleven, Heidi; Puchades, Maja; Leergaard, Trygve Brauns & Bjaalie, Jan G. (2018). Data integration through digital brain atlasing: Making diverse neuroscience data discoverable using Human Brain Project infrastructure.
  • Papp, Eszter Agnes; Bjaalie, Jan G. & Leergaard, Trygve Brauns (2018). Volumetric atlasing in the rodent brain: connecting experimental image data to standard anatomical space. Full text in Research Archive. Show summary
  • von Linstow, Christian Ulrich; Yates, Sharon Christine; Leergaard, Trygve B.; Plank, A-C; von Hörsten, S.; Puchades, Maja & Bjaalie, Jan G. (2018). Whole brain analysis of Huntingtin aggregates in the F344 transgenic rat model of Huntington’s disease.
  • Øvsthus, Martin; Bjerke, Ingvild Elise; Yates, Sharon Christine; Bjaalie, Jan G. & Leergaard, Trygve Brauns (2018). Mapping topographical organization in mouse brain subcortical axonal projections using Human Brain Project infrastructure.
  • Andersson, Krister Andreas; Bell, Simon; Bjerke, Ingvild Elise; Øvsthus, Martin; Blixhavn, Camilla Hagen; Kleven, Heidi; Puchades, Maja; Suzen, M; Denker, Michael; Davison, A.; Grün, Sonja; Leprince, Y; Dickscheid, Timo; McMurtrie, C; Telefont, Martin; Muller, Jeff; Leergaard, Trygve B. & Bjaalie, Jan G. (2017). Submitting data and metadata through the HBP Data Workbench: Concepts, data flows, policies, and best practices.
  • Andersson, Krister; Øvsthus, Martin; Bjerke, Ingvild Elise; Puchades, Maja; Telefont, Martin; Jeff, Muller; Dickscheid, Timo; Leergaard, Trygve Brauns & Bjaalie, Jan G. (2017). Data integration through digital brain atlasing: Human Brain Project infrastructure. Show summary
  • Bjerke, Ingvild Elise; Andersson, Krister Andreas; Øvsthus, Martin; Puchades, Maja; Bjaalie, Jan G. & Leergaard, Trygve B. (2017). Navigating the rodent brain: Best practice recommendations for determining and documenting spatial location for neuroscience data.
  • Bjerke, Ingvild Elise; Andersson, Krister; Øvsthus, Martin; Puchades, Maja; Bjaalie, Jan G. & Leergaard, Trygve Brauns (2017). Determining and documenting the anatomical location of experimental neuroscience data: Best practice recommendations. Show summary
  • Coello, Sebastian Christopher; Leergaard, Trygve B. & Bjaalie, Jan G. (2017). Tackling the normalization of 2-D rodent histology sections in a 3-D coordinate space.
  • Coello, Sebastian Christopher; Leergaard, Trygve B. & Bjaalie, Jan G. (2017). Tackling the normalization of 2-D rodent histology sections in a 3-D coordinate space.
  • Imad, Jala; Kleven, Heidi; Clascá, Francisco; Wennberg, Arvind Eirik; Osen, Kirsten Kjelsberg; Coello, Sebastian Christopher; Csúcs, Gergely; Papp, Eszter Agnes; Witter, Menno; Bjaalie, Jan G. & Leergaard, Trygve B. (2017). Enriching and adding detail to the Waxholm Space rat brain reference atlas.
  • Imad, Jala; Osen, Kirsten Kjelsberg; Clascá, Francisco; Wennberg, Arvind E.; Coello, Sebastian Christopher; Csúcs, Gergely; Papp, Eszter Agnes; Bjaalie, Jan G. & Leergaard, Trygve Brauns (2017). Enriching and Adding Detail to the Waxholm Space Rat Brain Reference Atlas. Show summary
  • Leergaard, Trygve B. (2017). Building and using rodent brain reference atlases for integration of experimental data.
  • Leprince, Y; Coello, Sebastian Christopher; Csúcs, Gergely; Chervakov, P; Darine, Dmitri Aleksandrovitsj; Øvsthus, Martin; Bjerke, Ingvild Elise; Yates, Sharon Christine; Puchades, Maja; Leergaard, Trygve B.; Dickscheid, Timo & Bjaalie, Jan G. (2017). Interactive tools for registering of 2D and 3D images to reference atlases.
  • Puchades, Maja; Csúcs, Gergely; Checinska, Martyna; Øvsthus, Martin; Bjerke, Ingvild Elise; Andersson, Krister; Leergaard, Trygve Brauns & Bjaalie, Jan G. (2017). Neuroinformatics tool and workflow for anchoring of serial histological images in rodent brain 3D space. Show summary
  • Puchades, Maja; Øvsthus, Martin; Bjerke, Ingvild Elise; Andersson, Krister; Csúcs, Gergely; Leergaard, Trygve Brauns & Bjaalie, Jan G. (2017). Data integration through digital brain atlasing: semiautomatic spatial registration of serial histological images to rodent brain 3D reference atlases. Show summary
  • Timonidis, Nestor; Bakker, Rembrandt; Øvsthus, Martin; Garcia-Amado, M; Porrero, C; Leergaard, Trygve B.; Clascá, Francisco & Tiesinga, Paul (2017). Towards predicting the full mesoconnectome based on data fusion.
  • Yates, Sharon Christine; Puchades, Maja; Coello, Sebastian Christopher; Kreshuk, Anna; Hartlage-Rübsamen, Maike; Rossner, Steffen; Leergaard, Trygve Brauns & Bjaalie, Jan G. (2017). Workflow for automated quantification and spatial analysis of labeling in microscoping rodent brain sections. Show summary
  • Yates, Sharon Christine; Puchades, Maja; Coello, Sebastian Christopher; Kreshuk, Anna; Hartlage-Rübsamen, Maike; Rossner, Steffen; Leergaard, Trygve Brauns & Bjaalie, Jan G. (2017). Workflow for automated quantification and spatial analysis of labelling in microscoping rodent brain sections.
  • Leergaard, Trygve B. (2016). Navigating the rodent brain: An anatomist’s guide to assigning location to brain image data.
  • Puchades, Maja; Bjerke, Ingvild Elise; Øvsthus, Martin; Andersson, Krister; Csúcs, Gergely; Leergaard, Trygve Brauns & Bjaalie, Jan G. (2016). Spatial registration of serial histological image data to reference brain atlases.
  • Blackstad, Jan Sigurd Beddari; Osen, Kirsten Kjelsberg; Scharfman, HE; Storm-Mathisen, Jon; Blackstad, Theodor & Leergaard, Trygve Brauns (2015). Hippocampal mossy cells in mink (Neovison vison).
  • Leergaard, Trygve Brauns (2015). Hjerneforskning i den digitale tidsalder: Fremtidens hjerneatlas.
  • Puchades, Maja Amedjkouh; Darine, Dmitri Aleksandrovitsj; Csúcs, Gergely; Lillehaug, Sveinung; Leergaard, Trygve Brauns & Bjaalie, Jan G. (2015). Feeding rodent brain data to computational models through HBP spatial atlas templates and knowledge graph portal.
  • Schubert, N; Axer, M; Graessel, D; Schober, M; Huynh, A; Huysegoms, M; Palomero-Gallagher, N; Bjaalie, Jan G.; Leergaard, Trygve Brauns; Zilles, K & Amunts, K (2015). 3D reconstructed fiber-, cyto- and receptorarchitecture of the rat brain transferred into the Waxholm Space atlas.
  • Bjaalie, Jan G. & Leergaard, Trygve Brauns (2014). Neuroscience in the information ages: Brain atlasing goes digital. META.  ISSN 1890-2987.  (2), s 14- 17
  • Leergaard, Trygve Brauns (2014). Navigating the rodent brain by digital atlasing.
  • Leergaard, Trygve Brauns & Bjaalie, Jan G. (2014). Infrastructure for digital atlasing of mouse and rat brain: Rodent Brain WorkBench.
  • Leergaard, Trygve Brauns; Coello, Christopher; Papp, Eszter Agnes; Ragan, Tim & Bjaalie, Jan G. (2014). Registration of serial two-photon data to rodent brain Waxholm Space. Frontiers in Neuroinformatics.  ISSN 1662-5196. . doi: 10.3389/conf.fninf.2014.18.00059
  • Leergaard, Trygve Brauns; Coello, Christopher; Papp, Eszter Agnes; Ragan, Tim & Bjaalie, Jan G. (2014). Registration of serial two-photon data to rodent brain Waxholm Space.
  • Leergaard, Trygve Brauns; Lillehaug, Sveinung; Papp, Eszter Agnes; Coello, Christopher; Ragan, Tim & Bjaalie, Jan G. (2014). Waxholm Space atlas template enriched with serial two-photon and histological data.
  • Leergaard, Trygve Brauns; Lillehaug, Sveinung; Yetman, Michael J.; Jankowsky, Joanna L. & Bjaalie, Jan G. (2014). Interactive brainwide atlas of tetracycline responsive trans-activator promoter mouse lines.
  • Leergaard, Trygve Brauns; Yetman, Michael J.; Lillehaug, Sveinung; Bjaalie, Jan G. & Jankowsky, Joanna L. (2014). Transgene expression in the neuropsin tTA driver line is not restricted to the entorhinal cortex.
  • Papp, Eszter Agnes; Leergaard, Trygve Brauns; Csucs, Gergely; Darine, Dmitri Aleksandrovitsj & Bjaalie, Jan G. (2014). Workflow for integration and analysis of histological data in rodent brain Waxholm Space.
  • Papp, Eszter Agnes; Leergaard, Trygve Brauns; Csucs, Gergely; Darine, Dmitri Aleksandrovitsj & Bjaalie, Jan G. (2014). Workflow for integration and analysis of histological data in rodent brain Waxholm Space. Frontiers in Neuroinformatics.  ISSN 1662-5196. . doi: 10.3389/conf.fninf.2014.18.00060
  • Bjaalie, Jan G.; Papp, Eszter Agnes; Kjonigsen, LJ; Johnson, GA; Witter, Menno & Leergaard, Trygve Brauns (2013). Waxholm Space Atlas of the rat brain with detailed hippocampal subdivisions. Show summary
  • Syverstad, Gry-Helen Enger; Lillehaug, Sveinung; Nilsson, Lars N. G.; Bjaalie, Jan G.; Leergaard, Trygve B. & Torp, Reidun (2013). Spatial distribution and variance of amyloid-beta load in middle-aged transgenic Alzheimer’s disease mice with both the Artic and Swedish AβPP mutations.
  • Syverstad, Gry-Helen Enger; Nuruddin, Syed; Lillehaug, Sveinung; Leergaard, Trygve B.; Haraldsen, Ira Hebold & Torp, Reidun (2013). Targeting gonadotroping-releasing hormone in Alzheimer’s disease.
  • Papp, Eszter Agnes; Leergaard, Trygve Brauns; Johnson, G. Allan & Bjaalie, Jan G. (2012). First generation Waxholm atlas of the Sprague-Dawley rat brain.
  • Kjønigsen, Lisa Jannicke; Leergaard, Trygve Brauns; Witter, Menno & Bjaalie, Jan G. (2011). Three-dimensional atlas framework for mapping of projections from the entorhinal cortex to the hippocampal formation in rat. Frontiers in Neuroinformatics.  ISSN 1662-5196. . doi: 10.3389/conf.fninf.2011.08.00129
  • Leergaard, Trygve Brauns (2011). Interpreting morphological substrates of diffusion MRI: Histological validation approaches and 3D rat brain atlasing.
  • Moene, Ivar Andre; Darine, Dmitri Aleksandrovitsj; Ramachandran, Muthuraja; Leergaard, Trygve Brauns & Bjaalie, Jan G. (2011). Rodent Brain Navigator: database and atlas system for microscopy and imaging data. Frontiers in Neuroinformatics.  ISSN 1662-5196. . doi: 10.3389/conf.fninf.2011.08.00159
  • Papp, Eszter Agnes; Leergaard, Trygve B.; Jiang, Yi; Johnson, G. Allan & Bjaalie, Jan G. (2011). Multimodal digital atlas of the rat brain: data integration in a high resolution volumetric template. Frontiers in Neuroinformatics.  ISSN 1662-5196. . doi: 10.3389/conf.fninf.2011.08.00013
  • Zakiewicz, Izabela Maria; Bjaalie, Jan G. & Leergaard, Trygve Brauns (2011). Neuroinformatics web applications for 3-D analysis of brain connectivity: anatomical organization of subcortical projections from whisker and forelimb regions of the rat somatosensory cortex. Frontiers in Neuroinformatics.  ISSN 1662-5196. . doi: 10.3389/conf.fninf.2011.08.00060
  • Antonsen, Bjørnar T; Jiang, Yi; Veraart, J; Van Dongen, Yvette C; Qu, Hong; Urbach, Yvonne K; Raber, Kerstin; Nguyen, Huu P.; Sijbers, J; von Hörsten, Stephan; Johnson, G A & Leergaard, Trygve Brauns (2010). Altered ex vivo diffusion MRI in basal ganglia of transgenic Huntington's disease rats.
  • Kjønigsen, Lisa Jannicke; Leergaard, Trygve Brauns; Witter, Menno & Bjaalie, Jan Gunnar (2010). Interactive atlas of the rat hippocampus: assigning location to experimental histological data using cyto- and chemoarchitectonical boundary definitions and a linked image repository.
  • Leergaard, Trygve Brauns (2010). Morphological phenotyping of rodent transgenic models of brain disease.
  • Van Dongen, Yvette C; Molvær, Arnold JN; van Camp, Nadja; Blockx, I; Urbach, Yvonne K; Raber, Kerstin; Van Der Linden, A; von Hörsten, Stephan; Bjaalie, Jan G. & Leergaard, Trygve Brauns (2010). Structural analysis of the cortico-basal ganglia connectivity in a transgenic rat model of Huntington's disease.
  • Van Dongen, Yvette C; Molvær, Arnold John Ngugi; Van Camp, Nadja; Blockx, I; Urbach, Yvonne K; Raber, Kerstin; Van Der Linden, A; von Hörsten, Stephan; Bjaalie, Jan G. & Leergaard, Trygve Brauns (2010). Reduced corticostriatal but intact striatofugal projections in transgenic rat model of Huntington's disease.
  • Zakiewicz, Izabela Maria; Van Dongen, Yvette C; Leergaard, Trygve Brauns & Bjaalie, Jan G. (2010). Workflow and database system for brain-wide mapping of axonal connectivity in rat.
  • Melsom, Caroline B.; Leergaard, Trygve Brauns; Darine, Dmitri Aleksandrovitsj; Dale, Anders M & Bjaalie, Jan G. (2009). Three-dimensional visualization of rat corticofugal axonal trajectories using manganese enhanced magnetic resonance imaging and digital atlasing. Frontiers in Neuroinformatics.  ISSN 1662-5196. . doi: 10.3389/conf.neuro.11.2009.08.027
  • White, Nathan; Leergaard, Trygve Brauns; De Crespigny, Alex & Dale, Anders M. (2009). A New Method for Resolving Complex Tissue Microstructures in Diffusion MRI.
  • Antonsen, Bjørnar; Jiang, Yi; Qu, Hong; Van Dongen, Yvette C; Urbach, Yvonne K.; Raber, Kerstin; Nguyen, Huu P.; von Hörsten, Stephan; Johnson, G. Allan & Leergaard, Trygve Brauns (2009). Altered diffusion MRI in the basal ganglia of transgenic rat model of Huntington’s disease.
  • Boy, J.; Schmidt, T.; Bottcher, M; Schumann, U.; Leergaard, Trygve Brauns; Odeh, Francis; Wolburg, H; Nuber, S.; Holzmann, C.; Schmitt, I; Zimmermann, F; Bjaalie, Jan G. & Riess, O. (2009). Clinical symptoms in SCA3 are reversible: a study using an inducible mouse model of SCA3. Journal of Neurochemistry.  ISSN 0022-3042.  110, s 97- 97
  • Kjønigsen, Lisa Jannicke; Leergaard, Trygve Brauns; Bjaalie, Jan G. & Witter, Menno P (2009). Interactive Resource for Cytoarchitectonic Delineation of the Rat Hippocampus Formation and Associated Parahippocampal Cortex.
  • Leergaard, Trygve Brauns (2009). Evaluation of neural network changes in transgenic rat model of Huntington’s disease: Preliminary findings.
  • Leergaard, Trygve Brauns (2009). Oppdagelsesreiser i hjernens nervenettverk.
  • Leergaard, Trygve Brauns; Antonsen, Bjørnar; Qu, Hong; Van Dongen, Yvette C; Jiang, Yi; Raber, Kerstin; Urbach, Yvonne; Nguyen, Huu P.; von Hörsten, Stephan & Johnson, G. Allan (2009). Ex vivo diffusion MRI measurements in symptomatic HD transgenic rats.
  • Odeh, U. R. Francis; Schmidt, T.; Boy, J.; Moene, Ivar Andre; Riess, O.; Bjaalie, Jan G. & Leergaard, Trygve Brauns (2009). Interactive mouse brain atlas of tetracycline-responsive calmodulin-dependent protein kinase II- and prion protein promoter expression. Frontiers in Neuroinformatics.  ISSN 1662-5196. . doi: 10.3389/conf.neuro.11.2009.08.012
  • Zakiewicz, Izabela Maria; Van Dongen, Yvette C; Moene, Ivar Andre; Leergaard, Trygve Brauns & Bjaalie, Jan G. (2009). Towards an interactive digital atlas system for exploring anatomical connectivity patterns in the entire rat brain.
  • White, Nathan; Leergaard, Trygve Brauns; Bolstad, Ingeborg; Bjaalie, Jan G.; D'Arceuil, Helen; De Crespigny, Alex & Dale, Anders M. (2008). Quantitative histological validation of fiber orientation distributions based on high-angular resolution diffusion imaging.
  • Hjørnevik, Trine; Darine, Dmitri Aleksandrovitsj; Qu, Hong; Willoch, Frode; Leergaard, Trygve Brauns & Bjaalie, Jan G. (2008). Three dimensional atlas system for mouse and rat brain imaging data.
  • Kjøde, Jan Olav; Darine, Dmitri Aleksandrovitsj; Leergaard, Trygve Brauns & Bjaalie, Jan G. (2008). Database application for managementof microscopic images.
  • Kjønigsen, Lisa Jannicke; Leergaard, Trygve Brauns; Kjøde, Jan Olav; Witter, Menno P & Bjaalie, Jan G. (2008). Interactive histological atlas system for anatomical parcellation of the rat hippocampus proper, fasciola and associated parahippocampal cortex. Show summary
  • Leergaard, Trygve Brauns (2008). Investigating Rodent Brain Neural Networks using Axonal tracing, Brain atlasing, Neuroimaging and Neuroinformatics.
  • Zakiewicz, Izabela Maria; Dongen, Yvette C Van; Kjøde, Jan Olav; Leergaard, Trygve Brauns & Bjaalie, Jan G. (2008). Digital atlas system for exploring axonal connections throughout the rat brain. Show summary
  • Zakiewicz, Izabela Maria; Van Dongen, Yvette C; Kjode, Jan Olav; Bore, A T; Leergaard, Trygve Brauns & Bjaalie, Jan G. (2008). Interactive microscopy via the web:exploring the neural network connections of the rat somatosensory cortex.

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Published Apr. 13, 2011 2:40 PM - Last modified Aug. 30, 2013 2:01 PM

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