Background
I am a computational physicist with strong background in computational biology currently working on the development of clinical prediction models for head and neck cancer. I obtained my PhD in Physics with focus on Computational Physics at the University of Coimbra (Portugal) in 2020. My thesis was about inherent biological mechanisms of tumour dynamics, such as the growing of new blood vessels and cellular migration.
Education
- 2015-2020 Ph.D in Physics, University of Coimbra - UC, Portugal.
- 2013-2015 Master in Science, Federal University of Pelotas - UFPel, Brazil.
- 2010-2012 Bachelor in Physics, University of Coimbra - UC, Portugal.
- 2009-2013 Bachelor in Physics, Federal University of Pelotas - UFPel, Brazil.
Publications
Regular papers
The ECM and tissue architecture are major determinants of early invasion mediated by E-cadherin dysfunction (2023) , S. Melo , P. Guerrero , M. Moreira Soares , J. R. Bordin , F. Carneiro , P. Carneiro , M. Beatriz Dias , J. Carvalho , J. Figueiredo , R. Seruca, Communications Biology
A multicenter randomized trial for quality of life evaluation by non-invasive intelligent tools during post-curative treatment follow-up for head and neck cancer: Clinical study protocol (2023) , S. Cavalieri, C. Vener, M. LeBlanc, L. Lopez-Perez, G. Fico, C. Resteghini, D. Monzani, G. Marton, G. Pravettoni, M. Moreira-Soares, D. E. Filippidou, A. Almeida, A. Bilbao, H. Mehanna, S. Singer, S. Thomas, L. Lacerenza, A. Manfuso, C. Copelli, F. Mercalli, A. Frigessi, E. Martinelli, L. Licitra, E. IF Fossen, K. Taylor, P. Nankivell, M. De, A. Abou-Foul, E. Estevez-Priego, M. F. Cabrera-Umpierrez, I. Alonso, S. Copelli, A. Ness, M. Pring, K. Hurley, BD4QoL Consortium, Frontiers in Oncology
Quantitative Analysis of Neuronal Mitochondrial Movement Reveals Patterns Resulting from Neurotoxicity of Rotenone and 6-Hydroxydopamine. (2021) , R. F. Simões, R. Pinho, M. Moreira-Soares, J. Kovarova, J. Neuzil, R. D. M. Travasso, P. J. Oliveira, T. Cunha-Oliveira, F. B. Pereira., FASEB Journal
Adhesion modulates cell morphology and migration within dense fibrous networks. M. Moreira-Soares, S. P. Cunha, J. R. Bordin, R. D. M. Travasso. 2020 J. Phys.: Condens. Matter 32 314001, pre-print: https://doi.org/10.1101/838995
Angiogenic Factors produced by Hypoxic Cells are a leading driver of Anastomoses in Sprouting Angiogenesis – a computational study, M. Moreira-Soares, R. Coimbra, L. Rebelo, J. Carvalho, R.D. M Travasso. Scientific Reports 8, 8726 (2018).
Preprints
TrajPy: empowering feature engineering for trajectory analysis across domains (2023) , M. Moreira-Soares, E. H. Mossmann, R. D. M. Travasso, J. R. Bordin, arxiv
Thesis & Dissertation
Multi-Phase-Field models for biological systems: From cells to vessels. M. Moreira-Soares (2020). Doctoral Thesis. University of Coimbra.
Coupling blood flow and growing vasculatures in three dimensions. (Portuguese only) M. Moreira-Soares. (2015). Master Dissertation. Universidade Federal de Pelotas.