Serhiy Pankiv

• Søreng, Kristiane; Pankiv, Serhiy; Bergsmark, Camilla; Haugsten, Ellen Margrethe; Dahl, Anette Kathinka & de la Ballina, Laura R [Show all 9 contributors for this article] (2022). ALFY localizes to early endosomes and cellular protrusions to facilitate directional cell migration . Journal of Cell Science. ISSN 0021-9533. 135(4). doi: 10.1242/jcs.259138. Full text in Research Archive
• Bindesbøll, Christian; Aas, Aleksander; Ogmundsdottir, Margret Helga; Pankiv, Serhiy; Reine, Trine M. & Zoncu, Roberto [Show all 7 contributors for this article] (2020). NBEAL1 controls SREBP2 processing and cholesterol metabolism and is a susceptibility locus for coronary artery disease. Scientific Reports. ISSN 2045-2322. 10(1). doi: 10.1038/s41598-020-61352-0. Full text in Research Archive
• Abudu, Yakubu Princely; Pankiv, Serhiy; Mathai, Benan John; Lamark, Trond; Johansen, Terje & Simonsen, Anne (2019). NIPSNAP1 and NIPSNAP2 act as “eat me” signals to allow sustained recruitment of autophagy receptors during mitophagy. Autophagy. ISSN 1554-8627. doi: 10.1080/15548627.2019.1637642.
• Abudu, Yakubu Princely; Pankiv, Serhiy; Mathai, Benan John; Lystad, Alf Håkon; Bindesbøll, Christian & Brenne, Hanne Britt [Show all 14 contributors for this article] (2019). NIPSNAP1 and NIPSNAP2 act as “eat-me signal” for mitophagy. Developmental Cell. ISSN 1534-5807. 49(4), p. 509–525.e12. doi: 10.1016/j.devcel.2019.03.013. Full text in Research Archive
• Søreng, Kristiane; Munson, Michael Joseph; Lamb, Christopher R.; Bjørndal, Gunnveig Toft; Pankiv, Serhiy & Carlsson, Sven R. [Show all 8 contributors for this article] (2018). SNX18 regulates ATG9A trafficking from recycling endosomes by recruiting Dynamin-2. EMBO Reports. ISSN 1469-221X. 19:e44837(4), p. 1–12. doi: 10.15252/embr.201744837. Full text in Research Archive
• Holland, Petter; Knævelsrud, Helene; Søreng, Kristiane; Mathai, Benan John; Lystad, Alf Håkon & Pankiv, Serhiy [Show all 16 contributors for this article] (2016). HS1BP3 negatively regulates autophagy by modulation of phosphatidic acid levels. Nature Communications. ISSN 2041-1723. 7. doi: 10.1038/ncomms13889. Full text in Research Archive
• Lystad, Alf Håkon; Ichimura, Yoshinobu; Takagi, K; Yang, Yinjie; Pankiv, Serhiy & Kanegae, Yumi [Show all 12 contributors for this article] (2014). Structural determinants in GABARAP required for the selective binding and recruitment of ALFY to LC3B-positive structures. EMBO Reports. ISSN 1469-221X. 15(5), p. 557–565. doi: 10.1002/embr.201338003.
• Lång, Emma Helena; Grudic, Amra; Pankiv, Serhiy; Bruserud, Øystein; Simonsen, Anne & Bjerkvig, Rolf [Show all 8 contributors for this article] (2012). The arsenic-based cure of acute promyelocytic leukemia promotes cytoplasmic sequestration of PML and PML/RARA through inhibition of PML body recycling. Blood. ISSN 0006-4971. 120(4), p. 847–857. doi: 10.1182/blood-2011-10-388496.
• Ravuri, Chandra Sekhar; Svineng, Gunbjørg; Pankiv, Serhiy & Huseby, nils-erik (2011). Endogenous production of reactive oxygen species by the NADPH oxidase complexes is a determinant of gamma gamma-glutamyltransferase expression. Free radical research. ISSN 1071-5762. 45(5), p. 600–610. doi: 10.3109/10715762.2011.564164.
• Pankiv, Serliy; Lamark, Trond; Bruun, Jack-Ansgar; Øvervatn, Aud Karin; Bjørkøy, Geir & Johansen, Terje (2010). Nucleocytoplasmic Shuttling of p62/SQSTM1 and Its Role in Recruitment of Nuclear Polyubiquitinated Proteins to Promyelocytic Leukemia Bodies. Journal of Biological Chemistry. ISSN 0021-9258. 285(8), p. 5941–5953. doi: 10.1074/jbc.M109.039925.
• Pankiv, Serliy; Alemu, Endalkachew; Brech, Andreas; Bruun, Jack-Ansgar; Lamark, Trond & Øvervatn, Aud Karin [Show all 8 contributors for this article] (2010). FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end-directed vesicle transport. Journal of Cell Biology. ISSN 0021-9525. 188(2), p. 253–269. doi: 10.1083/jcb.200907015. Show summary

  Autophagy is the main eukaryotic degradation pathway for long-lived proteins, protein aggregates, and cytosolic organelles. Although the protein machinery involved in the biogenesis of autophagic vesicles is well described, very little is known about the mechanism of cytosolic transport of autophagosomes. In this study, we have identified an adaptor protein complex, formed by the two autophagic membrane-associated proteins LC3 and Rab7 and the novel FYVE and coiled-coil (CC) domain-containing protein FYCO1, that promotes microtubule (MT) plus end-directed transport of autophagic vesicles. We have characterized the LC3-, Rab7-, and phosphatidylinositol-3-phosphate-binding domains in FYCO1 and mapped part of the CC region essential for MT plus end-directed transport. We also propose a mechanism for selective autophagosomal membrane recruitment of FYCO1.

• Bjørkøy, Geir; Lamark, Trond; Pankiv, Serliy; Øvervatn, Aud Karin; Brech, Andreas & Johansen, Terje (2009). MONITORING AUTOPHAGIC DEGRADATION OF P62/SQSTM1. Methods in Enzymology. ISSN 0076-6879. 452, p. 181–197. doi: 10.1016/S0076-6879(08)03612-4.
• Pankiv, Serliy; Clausen, Terje; Lamark, Trond; Brech, A; Bruun, Jack-Ansgar & Outzen, heidi [Show all 9 contributors for this article] (2007). p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy. Journal of Biological Chemistry. ISSN 0021-9258. 282, p. 24131–24145. doi: 10.1074/jbc.M702824200.
• MØller, seila; Pankiv, Serliy; Johannessen, Mona; Moens, Ugo & Huseby, nils-erik (2007). gamma-Glutamyltransferase is upregulated after oxidative stress through the Ras signal transduction pathway in rat colon carcinoma cells. Free radical research. ISSN 1071-5762. 41(12), p. 1376–1384.
• Pankiv, Serliy; Møller, Seila; Bjørkøy, Geir; Moens, Ugo & Huseby, Nils-Erik (2006). Radiation-induced upregulation of gamma-glutamyltransferase in colon carcinoma cells is mediated through the Ras signal transduction pathway. Biochimica et Biophysica Acta - General Subjects. ISSN 0304-4165. 1760.

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• Pankiv, Serhiy & Johansen, Terje (2010). FYCO1 Linking autophagosomes to microtubule plus end-directing molecular motors. Autophagy. ISSN 1554-8627. 6(4), p. 550–552.
• Bjørkøy, Geir; Lamark, Trond; Pankiv, Serliy; Brech, A; Outzen, heidi & Perander, maria [Show all 9 contributors for this article] (2006). P62/SQSTM1: A direct link betwwen polyubiquitinated preotein aggregates and LC3.
• Bjørkøy, Geir; Lamark, Trond; Pankiv, Serliy; Brech, A; Outzen, heidi & Øvervatn, Aud [Show all 8 contributors for this article] (2006). p62 as a direct link between protein aggregates and the autophgic machinery.
• Bjørkøy, Geir; Lamark, Trond; Pankiv, Serliy; Brech, A; Outzen, heidi & Perander, maria [Show all 9 contributors for this article] (2006). P62/SQSTM1: A direct link betwwen polyubiquitinated preotein aggregates and LC3.
• Bjørkøy, Geir; Lamark, Trond; Pankiv, Serliy; Brech, A; Outzen, heidi & Perander, maria [Show all 9 contributors for this article] (2006). P62/SQSTM1: A direct link betwwen polyubiquitinated preotein aggregates and LC3.

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