Reidun Torp

Associate Professor - Molecular Neuroscience
Image of Reidun Torp
Norwegian version of this page
Phone +47-22851269
Room 1323
Visiting address Sognsvannsveien 9 Domus Medica 0372 OSLO
Postal address Postboks 1105 Blindern 0317 OSLO


  • Stahl, Katja; Rahmani, Soulmaz; Prydz, Agnete; Skauli, Nadia; MacAulay, Nanna; Mylonakou, Maria-Niki; Torp, Reidun; Skare, Øivind; Berg, Torill; Leergaard, Trygve Brauns; Paulsen, Ragnhild Elisabeth; Ottersen, Ole Petter & Amiry-Moghaddam, Mahmood (2018). Targeted deletion of the aquaglyceroporin AQP9 is protective in a mouse model of Parkinson's disease. PLoS ONE.  ISSN 1932-6203.  13(3) . doi: 10.1371/journal.pone.0194896 Show summary
  • Yang, Jing; Zhang, Rui; Shi, Changhe; Mao, Chengyuan; Yang, Zhihua; Suo, Zhenhe; Torp, Reidun & Xu, Yuming (2017). AQP4 Association with Amyloid Deposition and Astrocyte Pathology in the Tg-ArcSwe Mouse Model of Alzheimer's Disease. Journal of Alzheimer's Disease.  ISSN 1387-2877.  57(1), s 157- 169 . doi: 10.3233/JAD-160957
  • Lillehaug, Sveinung; Syverstad, Gry-Helen Enger; Nilsson, Lars; Bjaalie, Jan G.; Leergaard, Trygve Brauns & Torp, Reidun (2014). Brainwide distribution and variance of amyloid-beta deposits in tg-ArcSwe mice. Neurobiology of Aging.  ISSN 0197-4580.  35(3), s 556- 564 . doi: 10.1016/j.neurobiolaging.2013.09.013
  • Nuruddin, Syed; Syverstad, Gry-Helen Enger; Lillehaug, Sveinung; Leergaard, Trygve Brauns; Nilsson, Lars; Ropstad, Erik; Krogenæs, Anette; Haraldsen, Ira Hebold & Torp, Reidun (2014). Elevated mRNA-Levels of Gonadotropin-Releasing Hormone and Its Receptor in Plaque-Bearing Alzheimer's Disease Transgenic Mice. PLoS ONE.  ISSN 1932-6203.  9(8) . doi: 10.1371/journal.pone.0103607
  • Lillenes, Meryl Sønderby; Støen, Mari; Gómez-Muñoz, Marta; Torp, Reidun; Günther, Clara-Cecilie; Nilsson, Lars & Tønjum, Tone (2013). Transient OGG1, APE1, PARP1 and Polβ expression in an Alzheimer's disease mouse model. Mechanisms of Ageing and Development.  ISSN 0047-6374.  134(10), s 467- 477 . doi: 10.1016/j.mad.2013.09.002 Show summary
  • Nagelhus, Erlend Arnulf; Amiry-Moghaddam, Mahmood; Bergersen, Linda Hildegard; Bjaalie, Jan G.; Eriksson, Jens; Gundersen, Vidar; Leergaard, Trygve Brauns; Morth, Jens Preben; Storm-Mathisen, Jon; Torp, Reidun; Walhovd, Kristine B & Tønjum, Tone (2013). The glia doctrine: Addressing the role of glial cells in healthy brain ageing. Mechanisms of Ageing and Development.  ISSN 0047-6374.  134(10), s 449- 459 . doi: 10.1016/j.mad.2013.10.001
  • Benfenati, Valentina; Stahl, Katja; Gomis-Perez, Carolina; Toffanin, Stefano; Sagnella, Anna; Torp, Reidun; Kaplan, David L; Ruani, Giampiero; Omenetto, Fiorenzo G; Zamboni, Roberto & Muccini, Michele (2012). Biofunctional Silk/Neuron Interfaces. Advanced Functional Materials.  ISSN 1616-301X.  22(9), s 1871- 1884 . doi: 10.1002/adfm.201102310
  • Stahl, Katja; Mylonakou, Maria-Niki; Skare, Øivind; Amiry-Moghaddam, Mahmood & Torp, Reidun (2011). Cytoprotective effects of growth factors: BDNF more potent than GDNF in an organotypic culture model of Parkinson's disease. Brain Research.  ISSN 0006-8993.  1378, s 105- 118 . doi: 10.1016/j.brainres.2010.12.090
  • Yang, Jing; Lunde, Lisa Kristina; Nuntagij, Paworn; Oguchi, Tomohiro; Camassa, Laura Maria Azzurra; Nilsson, Lars N. G.; Lannfelt, L.; Xu, Y; Amiry-Moghaddam, Mahmood; Ottersen, Ole Petter & Torp, Reidun (2011). Loss of Astrocyte Polarization in the Tg-ArcSwe Mouse Model of Alzheimer's Disease. Journal of Alzheimer's Disease.  ISSN 1387-2877. . doi: 10.3233/JAD-2011-110725
  • Nuntagij, Paworn; Oddo, Salvatore; LaFerla, Frank M.; Kotchabhakdi, Naiphininch; Ottersen, Ole Petter & Torp, Reidun (2009). Amyloid Deposits Show Complexity and Intimate Spatial Relationship with Dendrosomatic Plasma Membranes: An Electron Microscopic 3D Reconstruction Analysis in 3xTg-AD Mice and Aged Canines. Journal of Alzheimer's Disease.  ISSN 1387-2877.  16(2), s 315- 323 . doi: 10.3233/JAD-2009-0962
  • Stahl, Katja; Skare, Øivind & Torp, Reidun (2009). Organotypic cultures as a model of Parkinson's Disease. A twist to an old model. Scientific World Journal.  ISSN 1537-744X.  9, s 811- 821 . doi: 10.1100/tsw.2009.68 Full text in Research Archive. Show summary
  • Nase, Gabriele; Helm, Paul Johannes; Oguchi, Tomohiro; Nilsson, L. N. G.; Lannfelt, L.; Ottersen, Ole Petter & Torp, Reidun (2008). Local impact of perivascular plaques on cerebral blood flow dynamics in a transgenic mouse model of Alzheimer's disease. Proceedings of SPIE, the International Society for Optical Engineering.  ISSN 0277-786X.  6860 . doi: 10.1117/12.762739 Full text in Research Archive.
  • Celsi, Fulvio; Svedberg, M; Unger, C; Cotman, CW; Carri, MT; Ottersen, Ole Petter; Nordberg, A & Torp, Reidun (2007). Beta-amyloid causes downregulation of calcineurin in neurons through induction of oxidative stress. Neurobiology of Disease.  ISSN 0969-9961.  26 . doi: 10.1016/j.nbd.2006.12.022
  • Oddo, S; Caccamo, A; Cheng, D; Jouleh, Bahareh; Torp, Reidun & LaFerla, FM (2007). Genetically augmenting tau levels does not modulate the onset or progression of A beta pathology in transgenic mice. Journal of Neurochemistry.  ISSN 0022-3042.  102, s 1053- 1063 . doi: 10.1111/j.1471-4159.2007.04607.x
  • Biskup, S; Moore, DJ; Celsi, Fulvio; Higashi, S; West, AB; Andrabi, SA; Kurkinen, K; Yu, SW; Savitt, JM; Waldvogel, HJ; Faull, R. L. M.; Emson, P. C.; Torp, Reidun; Ottersen, Ole Petter; Dawson, TM & Dawson, VL (2006). Localization of LRRK2 to membranous and vesicular structures in mammalian brain. Annals of Neurology.  ISSN 0364-5134.  60(5), s 557- 569
  • Mathisen, Thomas Misje; Nagelhus, Erlend Arnulf; Juoleh, Bahareh; Torp, Reidun; Frydenlund, Didrik Søli; Mylonakou, Maria-Niki; Amiry-Moghaddam, Mahmood Reza; Covolan, Luciene; Utvik, Jo Kristian; Riber, Bjørg; Gujord, Karen Marie; Knutsen, Jorunn; Skare, Øivind; Laake, Petter; Davanger, Svend; Haug, Finn-Mogens Smejda; Rinvik, Eric & Ottersen, Ole Petter (2006). Postembedding Immunogold Cytochemistry of Membrane Molecules and Amino Acid Transmitters in the Central Nervous System, In L. Záborszky; F. Wouterlood & J.L. Lanciego (ed.),  Neuroanatomical Tract Tracing: Molecules, Neurons, & Systems.  Springer Science+Business Media B.V..  ISBN 0-387-28941-0.  3.  s 72 - 108
  • Torp, Reidun; Singh, Preet Bano; Sørensen, Dag Reidar; Dietrichs, Espen & Hirschberg, Henry (2006). Vekstfaktorer som nevroprotektiv behandling ved Parkinsons sykdom?. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  126(7), s 899- 901
  • Bernard-Trifilo, JA; Kramar, EA; Torp, Reidun; Lin, CY; Pineda, EA; Lynch, G & Gall, CM (2005). Integrin signaling cascades are operational in adult hippocampal synapses and modulate NMDA receptor physiology. Journal of Neurochemistry.  ISSN 0022-3042.  93
  • Zhang, L; Shimoji, M; Thomas, B; Moore, DJ; Yu, SW; Marupudi, NI; Torp, Reidun; Torgner, Ingeborg Aasland; Ottersen, Ole Petter; Dawson, TM & Dawson, VL (2005). Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis. Human Molecular Genetics.  ISSN 0964-6906.  14, s 2063- 2073
  • Rissman, RA; Poon, WW; Blurton-Jones, M; Torp, Reidun; Oddo, S; Vitek, MP; LaFerla, FM; Rohn, TT & Cotman, CW (2004). Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology. Journal of Clinical Investigation.  ISSN 0021-9738.  114(1), s 121- 130
  • Torp, Reidun; Ottersen, Ole Petter; Cotman, C. W. & Head, E. (2003). Identification of neuronal plasma membrane microdomains that colocalize beta-amyloid and presenilin: implications for APP processing. Neuroscience.  ISSN 0306-4522.  120(2), s 291- 300
  • Head, E. & Torp, Reidun (2002). Insights into Abeta and presenilin from a canine model of human brain aging. Neurobiology of Disease.  ISSN 0969-9961.  (1), s 1- 10
  • Burton, Brent P.; McCormick, Bruce H.; Torp, Reidun & Fallon, James H. (2001). Three-dimensional reconstruction of neuronal forests. Neurocomputing.  ISSN 0925-2312.  38-40, s 1643- 1650
  • Torp, Reidun & Ottersen, Ole Petter (2001). Alzheimers sykdom: er forebygging mulig?. DIAforskningsnytt (Oslo).  ISSN 0808-1212.  5(4), s 1- 2
  • Bassem, Y. A.; Head, E.; Ibrahim, M. A.; Torp, Reidun; Tenner, A. J.; Kim, R. C.; Lott, I. T. & Cotman, C. W. (2000). Molecular dating of senile plaques in the brains of individuals with Down syndrome and in aged dogs. Experimental Neurology.  ISSN 0014-4886.  163, s 111- 122
  • Torp, Reidun; Head, E. & Cotman, C. W. (2000). Ultrastructural analyses of b-amyloid in the aged dog brain: Neuronal b-amyloid is localized to the plasma membrane. Progress in Neuro-psychopharmacology and Biological Psychiatry.  ISSN 0278-5846.  24, s 801- 810
  • Torp, Reidun; Head, E.; Milgram, N. W.; Hahn, F.; Ottersen, Ole Petter & Cotman, C. W. (2000). Ultrastructural evidence of fibrillar beta-amyloid associated with neuronal membranes in behaviorally characterized aged dog brains. Neuroscience.  ISSN 0306-4522.  96, s 495- 506
  • Torp, Reidun; Head, E.; Milgram, N. W.; Hahn, F.; Ottersen, Ole Petter & Cotman, C. W. (2000). Ultrastructural evidence of fibrillar beta-amyloid associated with neuronal membranes in behaviorally characterized aged dog brains. Neuroscience.  ISSN 0306-4522.  96, s 495- 506
  • Guthman, A.; Fritschy, J.-M.; Ottersen, Ole Petter; Torp, Reidun & Herbert, H. (1998). GABA, GABA transporters, GABA(A) receptor subunits, and GAD mRNAs in the rat parabrachial and Kolliker-Fuse nuclei. Journal of Comparative Neurology.  ISSN 0021-9967.  400, s 229- 243
  • Nagelhus, Erlend Arnulf; Veruki, M. L.; Torp, Reidun; Haug, Finn-Mogens Smejda; Laake, Jon Henrik; Nielsen, S.P.; Agre, P. & Ottersen, Ole Petter (1998). Aquaporin-4 water channel protein in the rat retina and optic nerve: polarized expression in Mûller cells and fibrous astrocytes. Journal of Neuroscience.  ISSN 0270-6474.  18, s 2506- 2519
  • Akbar, M. T.; Torp, Reidun; Danbolt, Niels Christian; Levy, Line Margrete; Meldrum, B. S. & Ottersen, Ole Petter (1997). Expression of glial glutamate transporters GLT-1 and GLAST is unchanged in the hippocampus in fully kindled rats. Neuroscience.  ISSN 0306-4522.  78(2), s 351- 359
  • Ottersen, Ole Petter; Chaudhry, Farrukh Abbas; Danbolt, Niels Christian; Laake, Jon Henrik; Nagelhus, Erlend Arnulf; Storm-Mathisen, Jon & Torp, Reidun (1997). Molecular organization of cerebellar glutamate synapses. Progress in Brain Research.  ISSN 0079-6123.  114, s 97- 107
  • Torp, Reidun; Hoover, Frank; Danbolt, Niels Christian; Storm-Mathisen, Jon & Ottersen, Ole Petter (1997). Differential distribution of the glutamate transporters GLT1 and rEAAC1 in rat cerebral cortex and thalamus: an in situ hybridization analysis. Anatomy and Embryology.  ISSN 0340-2061.  195, s 317- 326
  • Ottersen, Ole Petter; Laake, Jon Henrik; Reichelt, W; Haug, Finn-Mogens Smejda & Torp, Reidun (1996). Ischemic disruption of glutamate homeostasis in brain: quantitative immunocytochemical analyses. Journal of Chemical Neuroanatomy.  ISSN 0891-0618.  12, s 1- 14
  • Bjørås, Magnar; Gjesdal, O.; Erickson, J.; Torp, Reidun; Ottersen, Ole Petter; Storm-Mathisen, Jon; Seeberg, Erling Christen & Danbolt, Niels Christian (1996). Cloning and expression of a neuronal rat brain glutamate transporter. Brain Research. Molecular Brain Research.  ISSN 0169-328X.  36, s 163- 168
  • Torp, Reidun; Lekieffre, D.; Levy, Line Margrete; Haug, Finn-Mogens Smejda; Danbolt, Niels Christian; Meldrum, B. S. & Ottersen, Ole Petter (1995). Reduced postischemic expression of a glial glutamate transporter, GLT1, in the rat hippocampus. Experimental Brain Research.  ISSN 0014-4819.  103(1), s 51- 58
  • Torp, Reidun; Danbolt, Niels Christian; Babaie, Eshrat; Bjoras, M.; Seeberg, Erling Christen; Storm-Mathisen, Jon & Ottersen, Ole Petter (1994). Differential expression of two glial glutamate transporters in the rat brain: an in situ hybridization study. European Journal of Neuroscience.  ISSN 0953-816X.  6(6), s 936- 942
  • Storm-Mathisen, Jon; Danbolt, Niels Christian; Rothe, F.; Torp, Reidun; Zhang, N. H.; Aas, J. E.; Kanner, B. I.; Langmoen, Ivar A. & Ottersen, Ole Petter (1992). Ultrastructural immunocytochemical observations on the localization, metabolism and transport of glutamate in normal and ischemic brain tissue. Progress in Brain Research.  ISSN 0079-6123.  94, s 225- 241
  • Bramham, C. R.; Torp, Reidun; Zhang, N. H.; Storm-Mathisen, Jon & Ottersen, Ole Petter (1990). Distribution of glutamate-like immunoreactivity in excitatory hippocampal pathways: a semiquantitative electron microscopic study in rats. Neuroscience.  ISSN 0306-4522.  39(2), s 405- 417
  • Ottersen, Ole Petter; Storm-Mathisen, Jon; Bramham, C. R.; Torp, Reidun; Laake, Jon Henrik & Gundersen, Vidar (1990). A quantitative electron microscopic immunocytochemical study of the distribution and synaptic handling of glutamate in rat hippocampus. Progress in Brain Research.  ISSN 0079-6123.  83, s 99- 114
  • Ottersen, Ole Petter; Torp, Reidun & Storm-Mathisen, Jon (1989). New aspects of the pathogenesis of ischemic brain damage. Possible involvement of excitatory amino acids]. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  109(26), s 2674- 2677

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  • Nuntagij, Paworn; oddo, salvatore; LaFerla, Frank M; Kotchabhakdi, Nick; Ottersen, Ole Petter & Torp, Reidun (2011). Electron Microscopic 3D Reconstruction Analysis of Amyloid Deposits in 3xTg-AD Mice and Aged Canines. IOS Press.  ISBN 978-1-60750-732-1.  13 s.

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  • Syverstad, Gry-Helen Enger; Lillehaug, Sveinung; Nilsson, Lars N. G.; Bjaalie, Jan G.; Leergaard, Trygve B. & Torp, Reidun (2013). Spatial distribution and variance of amyloid-beta load in middle-aged transgenic Alzheimer’s disease mice with both the Artic and Swedish AβPP mutations.
  • Syverstad, Gry-Helen Enger; Nuruddin, Syed; Lillehaug, Sveinung; Leergaard, Trygve B.; Haraldsen, Ira Hebold & Torp, Reidun (2013). Targeting gonadotroping-releasing hormone in Alzheimer’s disease.
  • Stahl, Katja; WEDEMEYER, MA; FERGUSON, D; NISTOR, GI; HARNESS, J; OKANO, H; YAMANAKA, S; Torp, Reidun & KEIRSTEAD, H (2011). Human induced pluripotent stem cell lines are capable of producing differentiated products of high purity.
  • Torp, Reidun (2011). Alzheimer på cellenivå.
  • Torp, Reidun (2011). Alzheimer´s sykdom; hva gjør forskerene?.
  • Torp, Reidun (2011). How to understand Alzheimer disease through microscopes.
  • Torp, Reidun (2011). Understanding plaque formation in models ofAlzheimer disease by use of microscopic techniques.
  • Jelsness-Jørgensen, Lars-Petter; Bernklev, Tomm; Henriksen, Magne; Torp, Reidun & Moum, Bjørn (2010). Chronic fatigue (CF) is 2-3 times more common in Norwegian IBD patients than the normal population (NP) and it significantly decreases the patients health-related quality of life (HRQOL). Scandinavian Journal of Gastroenterology.  ISSN 0036-5521.  45, s 50- 51
  • Torp, Reidun; Jouleh, B; Margol, L; Keyed, R; Head, E & Glabe, C (2004). Soluble Oligomers of Beta-amyloid within human brain.
  • Torp, Reidun; Jouleh, B; Oddo, S & LaFerla, FM (2004). Ultrastructural analysis of triple-transgenic model of Alzheimer's Disease.
  • Preet, Bano; Hirschberg, Henry; Sørensen, Dag R.; Singh, Narpinder; Dietrichs, Espen & Torp, Reidun (2003). Starting an experimental Parkinsonism project: evalution of 6-OHDA lesions of the nigrostriatal pathway monitored by immunohistochemistry. Nevrodagene 2003..  (16), s 47
  • Torp, Reidun; Head, E.; Cotman, C. W. & Ottersen, Ole Petter (1999). A-b42 is associated with the plasma membrane of cortical neurons in aged canines.
  • Guthman, A.; Fritschy, J.-M.; Ottersen, Ole Petter; Torp, Reidun; Feil, R. & Herbert, H. (1996). GABA, GAD AND GABAA-RECEPTORS IN THE RAT PARABRACHIAL COMPLEX.

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Published Apr. 13, 2011 2:41 PM - Last modified Jan. 31, 2012 3:43 PM