Åslaug Helland

Professor II - Department of Oncology
Image of Åslaug Helland
Norwegian version of this page
Phone +47-22934431
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Visiting address Ullernchausseen 70 None 0372 OSLO
Postal address Postboks 4950 Nydalen 0424 OSLO

Publications

  • Bergholtz, Helga; Lien, Tonje Gulbrandsen; Ursin, Giske; Holmen, Marit Muri; Helland, Åslaug; Sørlie, Therese & Haakensen, Vilde Drageset (2019). A Longitudinal Study of the Association between Mammographic Density and Gene Expression in Normal Breast Tissue. Journal of mammary gland biology and neoplasia.  ISSN 1083-3021.  s 1- 13 . doi: 10.1007/s10911-018-09423-x
  • Öjlert, Åsa Kristine; Halvorsen, Anita; Nebdal, Daniel; Lund-Iversen, Marius; Solberg, Steinar; Brustugun, Odd Terje; Lingjærde, Ole Christian & Helland, Åslaug (2019). The immune microenvironment in non‐small cell lung cancer is predictive of prognosis after surgery. Molecular Oncology.  ISSN 1574-7891.  13, s 1166- 1179 . doi: 10.1002/1878-0261.12475
  • Shao, Borong; Bjaanæs, Maria Moksnes; Helland, Åslaug; Schütte, Christof & Conrad, Tim (2019). EMT network-based feature selection improves prognosis prediction in lung adenocarcinoma. PLOS ONE.  ISSN 1932-6203.  14:e0204186(1), s 1- 20 . doi: 10.1371/journal.pone.0204186
  • Solberg, Steinar; Nilssen, Yngvar; Brustugun, Odd Terje; Grimsrud, Tom Kristian; Haram, Per Magnus; Helbekkmo, Nina; Helland, Åslaug; Hjelde, Harald Harris; Jakobsen, Bjørn; Møller, Bjørn; Petersen, Martin; Strand, Trond-Eirik; Wahl, Sissel Gyrid Freim; Aanerud, Marianne & Fjellbirkeland, Lars (2019). Increase in curative treatment and survival of lung cancer in Norway 2001-2016. European Journal of Epidemiology (EJE).  ISSN 0393-2990.  s 1- 5 . doi: 10.1007/s10654-019-00536-z
  • Zhang, Ruyang; Lai, Linjing; Dong, Xuesi; He, Jieyu; You, Dongfang; Chen, Chao; Lin, Lijuan; Zhu, Ying; Huang, Hui; Shen, Sipeng; Wei, Liangmin; Chen, Xin; Guo, Yichen; Liu, Liya; Su, Li; Shafer, Andrea; Moran, Sebastian; Fleischer, Thomas; Bjaanæs, Maria Moksnes; Karlsson, Anna; Planck, Maria; Staaf, Johan; Helland, Åslaug; Esteller, Manel; Wei, Yongyue; Chen, Feng & Christiani, David C. (2019). SIPA1L3 methylation modifies the benefit of smoking cessation on lung adenocarcinoma survival: an epigenomic-smoking interaction analysis. Molecular Oncology.  ISSN 1574-7891.  13(5), s 1235- 1248 . doi: 10.1002/1878-0261.12482
  • Zhang, Ruyang; Lai, Linjing; He, Jieyu; Chen, Chao; You, Dongfang; Duan, Weiwei; Dong, Xuesi; Zhu, Ying; Lin, Lijuan; Shen, Sipeng; Guo, Yichen; Su, Li; Shafer, Andrea; Moran, Sebastian; Fleischer, Thomas; Bjaanæs, Maria Moksnes; Karlsson, Anna; Planck, Maria; Staaf, Johan; Helland, Åslaug; Esteller, Manel; Wei, Yongyue; Chen, Feng & Christiani, David C. (2019). EGLN2 DNA methylation and expression interact with HIF1A to affect survival of early-stage NSCLC. Epigenetics.  ISSN 1559-2294.  14(2), s 118- 129 . doi: 10.1080/15592294.2019.1573066
  • Abravan, Azadeh; Eide, Hanne Astrid; Løndalen, Ayca; Helland, Åslaug & Malinen, Eirik (2018). Mapping bone marrow response in the vertebral column by positron emission tomography following radiotherapy and erlotinib therapy of lung cancer. Molecular Imaging and Biology.  ISSN 1536-1632.  21(2), s 391- 398 . doi: 10.1007/s11307-018-1226-7
  • Berg, Janna; Halvorsen, Ann Rita; Bengtson, May-Bente; Tasken, Kristin Austlid; Mælandsmo, Gunhild Mari; Yndestad, Arne; Halvorsen, Bente; Brustugun, Odd Terje; Aukrust, Pål; Ueland, Thor & Helland, Åslaug (2018). Levels and prognostic impact of circulating markers of inflammation, endothelial activation and extracellular matrix remodelling in patients with lung cancer and chronic obstructive pulmonary disease. BMC Cancer.  ISSN 1471-2407.  18(1) . doi: 10.1186/s12885-018-4659-0
  • Brustugun, Odd Terje; Grønberg, Bjørn Henning; Fjellbirkeland, Lars; Helbekkmo, Nina; Aanerud, Marianne; Grimsrud, Tom Kristian; Helland, Åslaug; Møller, Bjørn; Nilssen, Yngvar; Strand, Trond-Eirik & Solberg, Steinar (2018). Substantial nation-wide improvement in lung cancer relative survival in Norway from 2000 to 2016. Lung Cancer.  ISSN 0169-5002.  122, s 138- 145 . doi: 10.1016/j.lungcan.2018.06.003
  • Digernes, Ingrid; Grøvik, Endre; Nilsen, Line; Saxhaug, Cathrine; Geier, Oliver; Reitan, Edmund; Sætre, Dag Ottar; Breivik, Birger; Reese, Timothy; Jacobsen, Kari Dolven; Helland, Åslaug & Emblem, Kyrre Eeg (2018). Brain metastases with poor vascular function are susceptible to pseudoprogression after stereotactic radiation surgery. Advances in Radiation Oncology.  ISSN 2452-1094.  3, s 559- 567 . doi: 10.1016/j.adro.2018.05.005
  • Eide, Hanne Astrid; Knudtsen, Ingerid Skjei; Sandhu, Vandana; Løndalen, Ayca; Halvorsen, Ann Rita; Abravan, Azadeh; Kure, Elin Wenche Hegland; Bogsrud, Trond; Brustugun, Odd Terje; Kyte, Jon A; Malinen, Eirik & Helland, Åslaug (2018). Serum cytokine profiles and metabolic tumor burden in patients with non-small cell lung cancer undergoing palliative thoracic radiation therapy. Advances in Radiation Oncology.  ISSN 2452-1094.  3(2), s 130- 138 . doi: 10.1016/j.adro.2017.12.007 Full text in Research Archive.
  • Gandara, David R.; von Pawel, Joachim; Mazieres, Julien; Sullivan, Richard; Helland, Åslaug; Han, Ji-Youn; Ponce Aix, Santiago; Rittmeyer, Achim; Barlesi, Fabrice; Kubo, Toshio; Park, Keunchil; Goldschmidt, Jerome; Gandhi, Mayank; Yun, Cindy; Yu, Wei; Matheny, Christina; He, Pei; Sandler, Alan; Ballinger, Marcus & Fehrenbacher, Louis (2018). Atezolizumab treatment beyond progression in advanced NSCLC: Results from the randomized, phase III OAK Study. Journal of Thoracic Oncology.  ISSN 1556-0864.  13(12), s 1906- 1918 . doi: 10.1016/j.jtho.2018.08.2027
  • George, Julie; Walter, Vonn; Peifer, Martin; Alexandrov, Ludmil B.; Seidel, Danila; Leenders, Frauke; Maas, Lukas; Müller, Christian; Dahmen, Ilona; Delhomme, Tiffany M.; Ardin, Maude; Leblay, Noemie; Byrnes, Graham; Sun, Ruping; De Reynies, Aurélien; McLeer-Florin, Anne; Bosco, Graziella; Malchers, Florian; Menon, Roopika; Altmüller, Janine; Becker, Christian; Nürnberg, Peter; Achter, Viktor; Lang, Ulrich; Schneider, Peter M.; Bogus, Magdalena; Soloway, Matthew G.; Wilkerson, Matthew D.; Cun, Yupeng; McKay, James D.; Moro-Sibilot, Denis; Brambilla, Christian G.; Lantuejoul, Sylvie; Lemaitre, Nicolas; Soltermann, Alex; Weder, Walter; Tischler, Verena; Brustugun, Odd Terje; Lund-Iversen, Marius; Helland, Åslaug; Solberg, Steinar; Ansén, Sascha; Wright, Gavin; Solomon, Benjamin; Roz, Luca; Pastorino, Ugo; Petersen, Iver; Clement, Joachim H.; Sänger, Jörg; Wolf, Jürgen; Vingron, Martin; Zander, Thomas; Perner, Sven; Travis, William D.; Haas, Stefan A.; Olivier, Magali; Foll, Matthieu; Büttner, Reinhard; Hayes, David Neil; Brambilla, Elisabeth; Fernandez-Cuesta, Lynnette & Thomas, Roman K. (2018). Integrative genomic profiling of large-cell neuroendocrine carcinomas reveals distinct subtypes of high-grade neuroendocrine lung tumors. Nature Communications.  ISSN 2041-1723.  9:1048, s 1- 13 . doi: 10.1038/s41467-018-03099-x Full text in Research Archive.
  • Guo, Yichen; Zhang, Ruyang; Shen, Sipeng; Wei, Yongyue; Salama, Sebastian Moran; Fleischer, Thomas; Bjaanæs, Maria Moksnes; Karlsson, Anna; Planck, Maria; Su, Li; Zhu, Zhaozhong; Staaf, Johan; Helland, Åslaug; Esteller, Manel & Christiani, David C. (2018). DNA methylation of LRRC3B: A biomarker for survival of early-stage non-small cell lung cancer patients. Cancer Epidemiology, Biomarkers and Prevention.  ISSN 1055-9965.  27(12), s 1527- 1535 . doi: 10.1158/1055-9965.EPI-18-0454
  • Halvorsen, Ann Rita; Sandhu, Vandana; Sprauten, Mette; Flote, Vidar Gordon; Kure, Elin Wenche Hegland; Brustugun, Odd Terje & Helland, Åslaug (2018). Circulating microRNAs associated with prolonged overall survival in lung cancer patients treated with nivolumab. Acta Oncologica.  ISSN 0284-186X.  57(9), s 1225- 1231 . doi: 10.1080/0284186X.2018.1465585
  • Novello, Silvia; Mazieres, Julien; Oh, In-Jae; de Castro, Javier Mayor; Migliorino, Maria Rita; Helland, Åslaug; Dziadziuszko, Rafał; Griesinger, Frank; Kotb, Ahmed; Zeaiter, Ali; Cardona, A; Balas, Bogdana; Johannsdottir, Hrefna; Das-Gupta, Ashis & Wolf, Jürgen (2018). Alectinib versus chemotherapy in crizotinib-pretreated anaplastic lymphoma kinase (ALK)-positive non-small-cell lung cancer: results from the phase III ALUR study. Annals of Oncology.  ISSN 0923-7534.  29(6), s 1409- 1416 . doi: 10.1093/annonc/mdy121
  • Rye, Inga Hansine; Trinh, Anne; Sætersdal, Anna Barbro; Nebdal, Daniel J.H.; Lingjærde, Ole Christian; Almendro, Vanessa; Polyak, Kornelia; Børresen-Dale, Anne-Lise; Helland, Åslaug; Markowetz, Florian & Russnes, Hege Elisabeth Giercksky (2018). Intratumor heterogeneity defines treatment-resistant HER2+ breast tumors. Molecular Oncology.  ISSN 1574-7891.  s 1- 18 . doi: 10.1002/1878-0261.12375
  • Shen, Sipeng; Zhang, Ruyang; Guo, Yichen; Loehrer, Elizabeth; Wei, Yongyue; Zhu, Ying; Yuan, Qianyu; Moran, Sebastian; Fleischer, Thomas; Bjaanæs, Maria Moksnes; Karlsson, Anna; Planck, Maria; Staaf, Johan; Helland, Åslaug; Esteller, Manel; Su, Li; Chen, Feng & Christiani, David C. (2018). A multi-omic study reveals BTG2 as a reliable prognostic marker for early-stage non-small cell lung cancer. Molecular Oncology.  ISSN 1574-7891.  12(6), s 913- 924 . doi: 10.1002/1878-0261.12204 Full text in Research Archive.
  • Stankovic, Branislava; Bjørhovde, Heidi Anine Korsmo; Skarshaug, Renate; Aamodt, Henrik; Frafjord, Astri; Müller, Elisabeth; Hammarström, Clara Louise; Beraki, Kahsai; Bækkevold, Espen Sønderaal; Woldbæk, Per R; Helland, Åslaug; Brustugun, Odd Terje; Øynebråten, Inger & Corthay, Alexandre (2018). Immune Cell Composition in Human Non-small Cell Lung Cancer. Frontiers in Immunology.  ISSN 1664-3224.  Feb(1), s 1- 22 . doi: 10.3389/fimmu.2018.03101
  • Terkelsen, Thilde; Haakensen, Vilde Drageset; Saldova, Radka; Gromov, Pavel; Hansen, Merete Kjær; Stockmann, Henning; Lingjærde, Ole Christian; Børresen-Dale, Anne-Lise; Papaleo, Elena; Helland, Åslaug; Rudd, Pauline M. & Gromova, Irina (2018). N-glycan signatures identified in tumor interstitial fluid and serum of breast cancer patients: association with tumor biology and clinical outcome. Molecular Oncology.  ISSN 1574-7891.  12(6), s 972- 990 . doi: 10.1002/1878-0261.12312
  • Wei, Youngyue; Liang, Junya; Zhang, Ruyang; Guo, Yichen; Shen, Sipeng; Su, Li; Lin, Xihong; Moran, Sebastian; Helland, Åslaug; Bjaanæs, Maria Moksnes; Karlsson, Anna; Planck, Maria; Esteller, Manel; Fleischer, Thomas; Staaf, Johan; Zhao, Yang; Chen, Feng & Christiani, David C (2018). Epigenetic modifications in KDM lysine demethylases associate with survival of early-stage NSCLC. Clinical Epigenetics.  ISSN 1868-7075.  10(41), s 1- 11 . doi: 10.1186/s13148-018-0474-3
  • Abravan, Azadeh; Eide, Hanne Astrid; Knudtsen, Ingerid Skjei; Løndalen, Ayca; Helland, Åslaug & Malinen, Eirik (2017). Assessment of pulmonary 18F-FDG-PET uptake and cytokine profiles in non-small cell lung cancer patients treated with radiotherapy and erlotinib. Clinical and Translational Radiation Oncology.  ISSN 2405-6308.  4, s 57- 63 . doi: 10.1016/j.ctro.2017.04.002
  • Abravan, Azadeh; Knudtsen, Ingerid Skjei; Eide, Hanne Astrid; Løndalen, Ayca; Helland, Åslaug; van Luijk, Peter & Malinen, Eirik (2017). A new method to assess pulmonary changes using 18F-fluoro-2-deoxyglucose positron emission tomography for lung cancer patients following radiotherapy. Acta Oncologica.  ISSN 0284-186X.  56(11), s 1597- 1603 . doi: 10.1080/0284186X.2017.1349336
  • Brustugun, Odd Terje; Sprauten, Mette & Helland, Åslaug (2017). Real-world data on nivolumab treatment of non-small cell lung cancer. Acta Oncologica.  ISSN 0284-186X.  56(3), s 438- 440 . doi: 10.1080/0284186X.2016.1253865
  • dannenfelser, ruth; Nome, Marianne Eikhom; Tahiri, Andliena; Ursini-Siegel, Josie; Vollan, Hans Kristian Moen; Haakensen, Vilde Drageset; Helland, Åslaug; Naume, Bjørn; Caldas, Carlos; Børresen-Dale, Anne-Lise; Kristensen, Vessela N. & Troyanskaya, Olga G. (2017). Data-driven analysis of immune infiltrate in a large cohort of breast cancer and its association with disease progression, ER activity, and genomic complexity. OncoTarget.  ISSN 1949-2553.  8(34), s 57121- 57133 . doi: 10.18632/oncotarget.19078 Full text in Research Archive. Show summary
  • Halvorsen, Ann Rita; Kristensen, Gunnar S Balle; Embleton, Andrew; Adusei, Cybil; Barretina-Ginesta, Maria Pilar; Beale, Philip & Helland, Åslaug (2017). Evaluation of prognostic and predictive significance of circulating MicroRNAs in ovarian cancer patients. Disease Markers.  ISSN 0278-0240.  2017:3098542, s 1- 9 . doi: 10.1155/2017/3098542
  • Helland, Åslaug; Brustugun, Odd Terje; Nakken, Sigve; Halvorsen, Ann Rita; Dønnem, Tom; Bremnes, Roy M.; Busund, Lill-Tove; Sun, Jinchang; Lorenz, Susanne; Solberg, Steinar; Jørgensen, Lars Hilmar; Vodak, Daniel; Myklebost, Ola; Hovig, Eivind & Meza, Leonardo Zepeda (2017). High number of kinome-mutations in non-small cell lung cancer is associated with reduced immune response and poor relapse-free survival. International Journal of Cancer.  ISSN 0020-7136.  141(1), s 184- 190 . doi: 10.1002/ijc.30726 Full text in Research Archive.
  • Mcgowan, Marc Kevin; Kleinberg, Lilach; Halvorsen, Ann Rita; Helland, Åslaug & Brustugun, Odd Terje (2017). NSCLC depend upon YAP expression and nuclear localization after acquiring resistance to EGFR inhibitors. Genes & cancer.  ISSN 1947-6019.  8(3-4), s 497- 504 . doi: 10.18632/genesandcancer.136 Full text in Research Archive. Show summary
  • Planchard, David; Smit, Egbert F; Groen, Harry J. M.; Mazieres, Julien; Besse, Benjamin; Helland, Åslaug; Giannone, Vanessa; D'Amelio, Anthony M; Zhang, Pingkuan; Mookerjee, Bijoyesh & Johnson, Bruce E. (2017). Dabrafenib plus trametinib in patients with previously untreated BRAF<sup>V600E</sup>-mutant metastatic non-small-cell lung cancer: an open-label, phase 2 trial. The Lancet Oncology.  ISSN 1470-2045.  18(10), s 1307- 1316 . doi: 10.1016/S1470-2045(17)30679-4
  • Berg, Janna; Fjellbirkeland, Lars; Suhrke, Pål; Jebsen, Peter Wilhelm; Lund-Iversen, Marius; Kleinberg, Lilach; Helgeland, Lars; Brustugun, Odd Terje & Helland, Åslaug (2016). EGFR mutation testing of lung cancer patients - Experiences from Vestfold Hospital Trust. Acta Oncologica.  ISSN 0284-186X.  55(2), s 149- 155 . doi: 10.3109/0284186X.2015.1062537
  • Bjaanæs, Maria Moksnes; Fleischer, Thomas; Halvorsen, Ann Rita; Daunay, Antoine; Busato, Florence; Solberg, Steinar; Jørgensen, Lars Hilmar; Kure, Elin H.; Edvardsen, Hege; Børresen-Dale, Anne-Lise; Brustugun, Odd Terje; Tost, Jörg; Kristensen, Vessela N. & Helland, Åslaug (2016). Genome-wide DNA methylation analyses in lung adenocarcinomas: Association with EGFR, KRAS and TP53 mutation status, gene expression and prognosis. Molecular Oncology.  ISSN 1574-7891.  10(2), s 330- 343 . doi: 10.1016/j.molonc.2015.10.021
  • Dunning, Alison M.; Michailidou, Kyriaki; Kuchenbaecker, Karoline B.; Thompson, Deborah; French, Juliet D.; Beesley, Jonathan; Healey, Catherine S.; Kar, Siddhartha; Pooley, Karen A.; Lopez-Knowles, Elena; Dicks, Ed; Barrowdale, Daniel; Sinnott-Armstrong, Nicholas A; Sallari, Richard C; Hillman, Kristine M.; Kaufmann, Susanne; Sivakumaran, Haran; Marjaneh, Mahdi Moradi; Lee, Jason S.; Hills, Margaret; Jarosz, Monika; Drury, Suzie; Canisius, Sander; KBolla, Manjeet; Dennis, Joe; Wang, Qin; LHopper, John; Southey, Melissa C.; Broeks, Annegien; Schmidt, Marjanka K.; Lophatananon, Artitaya; Muir, Kenneth; Beckmann, Matthias W.; Fasching, Peter A.; Dos-Santos-Silva, Isabel; Peto, Julian; Sawyer, Elinor J.; Tomlinson, Ian; Burwinkel, Barbara; Marme, Frederik; Guenel, Pascal; Truong, Therse; Bojesen, Stig E.; Flyger, Henrik; Gonzlez-Neira, Anna; Perez, Jose I.A.; Anton-Culver, Hoda; Eunjung, Lee; Arndt, Volker; Brenner, Hermann; Meindl, Alfons; Schmutzler, Rita K.; Brauch, Hiltrud; Hamann, Ute; Aittomki, Kristiina; Blomqvist, Carl; Ito, Hidemi; Matsuo, Keitaro; Bogdanova, Natasha; Dörk, Thilo; Lindblom, Annika; Margolin, Sara; Kosma, Veli-Matti; Mannermaa, Arto; Tseng, Chiu-Chen; Wu, Anna H.; Lambrechts, Diether; Wildiers, Hans; Chang-Claude, Jenny; Rudolph, Anja; Peterlongo, Paolo; Radice, Paolo; Olson, Janet E.; Giles, Graham G.; Milne, Roger L.; Haiman, Christopher A.; Henderson, Brian E.; Goldberg, Mark S.; Teo, Soo H.; Yip, Cheng Har; Nordgard, Silje H.; Børresen-Dale, Anne-Lise; Kristensen, Vessela N.; Long, Jirong; Zheng, Wei; Pylks, Katri; Winqvist, Robert; Andrulis, Irene L.; Knight, Julia A.; Devilee, Peter; Seynaeve, Caroline; Figueroa, Jonine; Sherman, Mark E.; Czene, Kamila; Darabi, Hatef; Hollestelle, Antoinette; Van Den Ouweland, Ans M.W.; Humphreys, Keith; Gao, Yu-Tang; Shu, Xiao-Ou; Cox, Angela; Cross, Simon S.; Blot, William; Cai, Qiuyin; Ghoussaini, Maya; Perkins, Barbara J.; Shah, Mitul; Choi, Ji-Yeob; Kang, Daehee; Lee, Soo Chin; Hartman, Mikael; Kabisch, Maria; Torres, Diana; Jakubowska, Anna; Lubinski, Jan; Brennan, Paul; Sangrajrang, Suleeporn; Ambrosone, Christine B; Toland, Amanda E; Shen, Chen-Yang; Wu, Pei-Ei; Orr, Nick; Swerdlow, Anthony; McGuffog, Lesley; Healey, Sue; Lee, Andrew; Kapuscinski, Miroslav; John, Esther M; Terry, Mary Beth; Daly, Mary B; Goldgar, David E; Buys, Saundra S; Janavicius, Ramunas; Tihomirova, Laima; Tung, Nadine; Dorfling, Cecilia M; Van Rensburg, Elizabeth J; Neuhausen, Susan L; Ejlertsen, Bent; Hansen, Thomas V.O.; Osorio, Ana; Benitez, Javier; Rando, Rachel; Weitzel, Jeffrey N; Bonanni, Bernardo; Peissel, Bernard; Manoukian, Siranoush; Papi, Laura; Ottini, Laura; Konstantopoulou, Irene; Apostolou, Paraskevi; Garber, Judy; Rashid, Muhammad Usman; Frost, Debra; Izatt, Louise; Ellis, Steve; Godwin, Andrew K; Arnold, Norbert; Niederacher, Dieter; Rhiem, Kerstin; Bogdanova-Markov, Nadja; Sagne, Charlotte; Stoppa-Lyonnet, Dominique; Damiola, Francesca; Sinilnikova, Olga M; Mazoyer, Sylvie; Isaacs, Claudine; MClaes, Kathleen B; De Leeneer, Kim; De La Hoya, Miguel; Caldes, Trinidad; Nevanlinna, Heli; Khan, Sofia; Mensenkamp, Arjen R; Hooning, Maartje J; Rookus, Matti A; Kwong, Ava; Olah, Edith; Diez, Orland; Brunet, Joan; Pujana, Miquel Angel; Gronwald, Jacek; Huzarski, Tomasz; Barkardottir, Rosa B; Laframboise, Rachel; Soucy, Penny; Montagna, Marco; Agata, Simona; Teixeira, Manuel R; Kyung Park, Sue; Lindor, Noralane; Couch, Fergus J; Tischkowitz, Marc; Foretova, Lenka; Vijai, Joseph; Offit, Kenneth; Singer, Christian F; Rappaport, Christine; MPhelan, Catherine; Greene, Mark H; Mai, Phuong L; Rennert, Gad; Imyanitov, Evgeny N; Hulick, Peter J; Phillips, Kelly-Anne; Piedmonte, Marion; Mulligan, Anna Marie; Glendon, Gord; Bojesen, Anders; Thomassen, Mads; Caligo, Maria A; Yoon, Sook-Yee; Friedman, Eitan; Laitman, Yael; Borg, Ake; Von Wachenfeldt, Anna; Ehrencrona, Hans; Rantala, Johanna; Olopade, Olufunmilayo I; Ganz, Patricia A; Nussbaum, Robert L; Gayther, Simon A; LNathanson, Katherine; Domchek, Susan M; Arun, Banu K; Mitchell, Gillian; Karlan, Beth Y; Lester, Jenny; Maskarinec, Gertraud; Woolcott, Christy; Scott, Christopher; Stone, Jennifer; Apicella, Carmel; Tamimi, Rulla; Luben, Robert; Khaw, Kay-Tee; Helland, Åslaug; Haakensen, Vilde Drageset; Dowsett, Mitch; Pharoah, Paul DP; Simard, Jacques; Hall, Per; Garca-Closas, Montserrat; Vachon, Celine; Chenevix-Trench, Georgia; Antoniou, Antonis C; Easton, Douglas F & Edwards, Stacey L (2016). Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170. Nature Genetics.  ISSN 1061-4036.  48(4), s 374- 386 . doi: 10.1038/ng.3521 Show summary
  • Dønnem, Tom; Kilvær, Thomas Karsten; Andersen, Sigve; Richardsen, Elin; Paulsen, Erna-Elise; Hald, Sigurd; Al-Saad, Samer; Brustugun, Odd Terje; Helland, Åslaug; Lund-Iversen, Marius; Solberg, Steinar; Grønberg, Bjørn Henning; Wahl, Sissel Gyrid Freim; Helgeland, Lars; Fløtten, Øystein; Pohl, M; Al-Shibli, Khalid; Sandanger, Torkjel M; Pezzella, Francesco; Busund, Lill-Tove & Bremnes, Roy M. (2016). Strategies for clinical implementation of TNM-Immunoscore in resected nonsmall-cell lung cancer. Annals of Oncology.  ISSN 0923-7534.  27(2), s 225- 232 . doi: 10.1093/annonc/mdv560
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  • Fernandez-Cuesta, Lynnette; Peifer, Martin; Lu, Xin; Sun, Ruping; Ozretic, Luka; Seidel, Danila; Zander, T; Leenders, Frauke; George, Julie; Müller, Christian; Dahmen, Ilona; Pinther, B; Bosco, Graziella; Konrad, Kathryn; Altmüller, Janine; Nürnberg, Peter; Achter, V; Lang, Ulrich; Schneider, Peter M.; Bogus, M; Soltermann, Alex; Brustugun, Odd Terje; Helland, Åslaug; Solberg, Steinar; Lund-Iversen, Marius; Ansén, Sascha; Stoelben, Erich; Wright, Gavin; Russell, Prudence; Wainer, Zoe; Solomon, Benjamin; Field, John K.; Hyde, R; Davies, Michael PA; Heukamp, Lukas C; Petersen, Iver; Perner, Sven; Lovly, Christine M; Cappuzzo, Federico; Travis, William D.; Wolf, Jürgen; Vingron, Martin; Brambilla, Elisabeth; Haas, Elisabeth; Buettner, R & Thomas, Roman K. (2014). Frequent mutations in chromatin-remodelling genes in pulmonary carcinoids. Nature Communications.  ISSN 2041-1723.  27(5), s 3518 . doi: 10.1038/ncomms4518
  • Fleischer, Thomas; Frigessi, Arnoldo; Johnson, Kevin C.; Edvardsen, Hege; Touleimat, Nizar; Klajic, Jovana; Riis, Margit; Haakensen, Vilde Drageset; Wärnberg, Fredrik; Naume, Bjørn; Helland, Åslaug; Børresen-Dale, Anne-Lise; Tost, Jörg; Christensen, Brock C. & Kristensen, Vessela N. (2014). Genome-wide DNA methylation profiles in progression to in situ and invasive carcinoma of the breast with impact on gene transcription and prognosis. Genome Biology.  ISSN 1465-6906.  15, s 435 . doi: 10.1186/s13059-014-0435-x Full text in Research Archive. Show summary
  • Halvorsen, Ann Rita; Helland, Åslaug; Fleischer, Thomas; Haug, Karen Marie; Grenaker, Grethe Irene; Nebdal, Daniel J.H.; Syljuåsen, Randi G.; Touleimat, Nizar; Busato, Florence; Tost, Jörg; Sætersdal, Anna Barbro; Børresen-Dale, Anne-Lise; Kristensen, Vessela N. & Edvardsen, Hege (2014). Differential DNA methylation analysis of breast cancer reveals the impact of immune signaling in radiation therapy. International Journal of Cancer.  ISSN 0020-7136.  135(9), s 2085- 2095 . doi: 10.1002/ijc.28862
  • Sagerup, Camilla Maria Troøien; Nymoen, Dag Andre; Halvorsen, Ann Rita; Lund-Iversen, Marius; Helland, Åslaug & Brustugun, Odd Terje (2014). Human papilloma virus detection and typing in 334 lung cancer patients. Acta Oncologica.  ISSN 0284-186X.  53(7), s 952- 957 . doi: 10.3109/0284186X.2013.879608
  • Saldova, Radka; Asadi Shehni, Akram; Haakensen, Vilde Drageset; Steinfeld, Israel; Hilliard, Mark; Kifer, Ilona; Helland, Åslaug; Yakhini, Zohar; Børresen-Dale, Anne-Lise & Rudd, Pauline M (2014). Association of N-glycosylation with breast carcinoma and systemic features using high-resolution quantitative UPLC. Journal of Proteome Research.  ISSN 1535-3893.  13(5), s 2314- 2327 . doi: 10.1021/pr401092y
  • Trinh, Anne; Rye, Inga Hansine; Almendro, Vanessa; Helland, Åslaug; Russnes, Hege Elisabeth Giercksky & Markowetz, Florian (2014). GoIFISH: a system for the quantification of single cell heterogeneity from IFISH images. Genome Biology.  ISSN 1465-6906.  15(8) . doi: 10.1186/s13059-014-0442-y
  • Baumbusch, Lars Oliver; Helland, Åslaug; Wang, Yun; Liestøl, Knut; Schaner, M.E.; Holm, Ruth; Etemadmoghadam, D; Alsop, Kathryn; Brown, Pat; Mitchell, Gillian; Fereday, Sian; deFazio, Anna; Bowtell, David D.L.; Kristensen, Gunnar S Balle; Lingjærde, Ole Christian & Børresen-Dale, Anne-Lise (2013). High Levels of Genomic Aberrations in Serous Ovarian Cancers Are Associated with Better Survival. PLOS ONE.  ISSN 1932-6203.  8(1) . doi: 10.1371/journal.pone.0054356
  • Nordgård, Oddmund; Dhillon, Gurpartap Singh; Solberg, Steinar; Jørgensen, Lars Hilmar; Halvorsen, Ann Rita; Smaaland, Rune; Brustugun, Odd Terje & Helland, Åslaug (2013). Novel Molecular Tumor Cell Markers in Regional Lymph Nodes and Blood Samples from Patients Undergoing Surgery for Non-Small Cell Lung Cancer. PLOS ONE.  ISSN 1932-6203.  8(5) . doi: 10.1371/journal.pone.0062153
  • Rajaram, Megha; Zhang, Jianping; Wang, Tim; Li, Jinyu; Kuscu, Cem; Qi, Huan; Kato, Mamoru; Grubor, Vladimir; Weil, Robert J.; Helland, Åslaug; Børresen-Dale, Anne-Lise; Cho, Kathleen R.; Levine, Douglas A.; Houghton, Alan N.; Wolchok, Jedd D.; Myeroff, Lois; Markowitz, Sanford D.; Lowe, Scott W.; Zhang, Michael; Krasnitz, Alex; Lucito, Robert; Mu, David & Powers, R. Scott (2013). Two distinct categories of focal deletions in cancer genomes. PLOS ONE.  ISSN 1932-6203.  8(6:e66264) . doi: 10.1371/journal.pone.0066264
  • Rud, Ane Kristine Kongsgaard; Borgen, Elin; Mælandsmo, Gunhild; Flatmark, Kjersti; Le, Hang Ngoc Thi; Josefsen, Dag; Solvoll, Ingjerd; Schirmer, Cecilie; Helland, Åslaug; Jørgensen, Lars Hilmar; Brustugun, Odd Terje; Fodstad, Øystein & Boye, Kjetil (2013). Clinical significance of disseminated tumour cells in non-small cell lung cancer. British Journal of Cancer.  ISSN 0007-0920.  109(5), s 1264- 1270 . doi: 10.1038/bjc.2013.450
  • Rud, Ane Kristine Kongsgaard; Pedersen, Kjetil Boye; Øijordsbakken, Miriam; Lund-Iversen, Marius; Halvorsen, Ann Rita; Solberg, Steinar; Berge, Gisle; Helland, Åslaug; Brustugun, Odd Terje & Mælandsmo, Gunhild (2013). Osteopontin is a prognostic biomarker in non-small cell lung cancer. BMC Cancer.  ISSN 1471-2407.  13 . doi: 10.1186/1471-2407-13-540 Full text in Research Archive.
  • Seidel, Danila; Zander, Thomas; Heukamp, Lukas C; Peifer, Martin; Bos, Marc; Fernandez-Cuesta, Lynnette; Leenders, Frauke; Lu, Xin; Ansén, Sascha; Gardizi, Masyar; Nguyen, Chau; Berg, Johannes; Russell, Prudence; Wainer, Zoe; Schildhaus, Hans-Ulrich; Rogers, Toni-Maree; Solomon, Benjamin; Pao, William; Carter, Scott L.; Getz, Gad; Hayes, D. Neil; Wilkerson, Matthew D.; Thunnissen, Erik; Travis, William D.; Perner, Sven; Wright, Gavin; Brambilla, Elisabeth; Büttner, Reinhard; Wolf, Jurgen; Thomas, Roman K.; Gabler, Franziska; Wilkening, Ines; Müller, Christian; Dahmen, Ilona; Menon, Roopika; König, Katharina; Albus, Kerstin; Merkelbach-Bruse, Sabine; Fassunke, Jana; Schmitz, Katja; Kuenstlinger, Helen; Kleine, Michaela A.; Binot, Elke; Querings, Silvia; Altmüller, Janine; Bäßmann, Ingelore; Numberg, P; Schneider, PM; Bogus, M; Buttner, R; Perner, S; Russell, P; Thunnissen, E; Travis, WD; Brambilla, E; Soltermann, A; Moch, H; Brustugun, Odd Terje; Solberg, Steinar; Lund-Iversen, Marius; Helland, Åslaug; Muley, T; Hoffmann, H; Schnabel, PA; Chen, Y; Groen, H; Timens, W; Sietsma, H; Clement, JH; Weder, W; Sanger, J; Stoelben, E; Ludwig, C; Engel-Riedel, W; Smit, E; Heideman, DAM; Snijders, PJF; Nogova, L; Sos, ML; Mattonet, C; Topelt, K; Scheffler, M; Goekkurt, E; Kappes, R; Kruger, S; Kambartel, K; Behringer, D; Schulte, W; Galetke, W; Randerath, W; Heldwein, M; Schlesinger, A; Serke, M; Hekmat, K; Frank, KF; Schnell, R; Reiser, M; Hunerliturkoglu, AN; Schmitz, S; Meffert, L; Ko, YD; Litt-Lampe, M; Gerigk, U; Fricke, R; Besse, B; Brambilla, C; Lantuejoul, S; Lorimier, P; Moro-Sibilot, D; Cappuzzo, F; Ligorio, C; Damiani, S; Field, JK; Hyde, R; Validire, P; Girard, P; Muscarella, LA; Fazio, VM; Hallek, M; Soria, JC; Carter, SL; Getz, G; Hayes, DN; Wilkerson, MD; Achter, V; Lang, U; Seidel, D; Zander, T; Heukamp, LC; Peifer, M; Bos, M; Pao, W; Wolf, J & Thomas, RK (2013). A Genomics-Based Classification of Human Lung Tumors. Science Translational Medicine.  ISSN 1946-6234.  5(209) . doi: 10.1126/scitranslmed.3006802
  • Brustugun, Odd Terje; Helland, Åslaug; Fjellbirkeland, Lars; Kleinberg, Lilach; Ariansen, Sarah Louise; Jebsen, Peter Wilhelm; Scott, Helge; Dønnem, Tom; Bremnes, Roy M.; Berg, Thomas; Grønberg, Bjørn Henning; Dai, Hong Yan; Wahl, Sissel Gyrid Freim; Mangseth, Kjersti & Helgeland, Lars (2012). Mutasjonstesting ved ikke-småcellet lungekreft. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  132(8), s 952- 955 . doi: 10.4045/tidsskr.11.1017
  • Helland, Åslaug; Solberg, Steinar & Brustugun, Odd Terje (2012). Incidence and Survival of Malignant Pleural Mesothelioma in Norway A Population-Based Study of 1686 Cases. Journal of Thoracic Oncology.  ISSN 1556-0864.  7(12), s 1858- 1861 . doi: 10.1097/JTO.0b013e318275b346
  • Kristensen, Vessela N.; Vaske, Charles J.; Ursini-Siegel, Josie; Van Loo, Peter; Nordgard, Silje H.; Sachidanandam, Ravi; Sørlie, Therese; Wärnberg, Fredrik; Haakensen, Vilde Drageset; Helland, Åslaug; Naume, Bjørn; Perou, Charles M; Haussler, David; Troyanskaya, Olga & Børresen-Dale, Anne-Lise (2012). Integrated molecular profiles of invasive breast tumors and ductal carcinoma in situ (DCIS) reveal differential vascular and interleukin signaling. Proceedings of the National Academy of Sciences of the United States of America.  ISSN 0027-8424.  109(8), s 2802- 2807 . doi: 10.1073/pnas.1108781108
  • Lund-Iversen, Marius; Kleinberg, Lilach; Fjellbirkeland, Lars; Helland, Åslaug & Brustugun, Odd Terje (2012). Clinicopathological Characteristics of 11 NSCLC Patients with EGFR-Exon 20 Mutations. Journal of Thoracic Oncology.  ISSN 1556-0864.  7(9), s 1471- 1473 . doi: 10.1097/JTO.0b013e3182614a9d
  • Sagerup, Camilla Maria Troøien; Småstuen, Milada C; Johannesen, Tom Børge; Helland, Åslaug & Brustugun, Odd Terje (2012). Increasing Age and Carcinoma Not Otherwise Specified A 20-Year Population Study of 40,118 Lung Cancer Patients. Journal of Thoracic Oncology.  ISSN 1556-0864.  7(1), s 57- 63 . doi: 10.1097/JTO.0b013e3182307f7e
  • Waldeland, Einar; Ramberg, Christina; Arnesen, Marius Røthe; Helland, Åslaug; Brustugun, Odd Terje & Malinen, Eirik (2012). Dosimetric impact of a frame-based strategy in stereotactic radiotherapy of lung tumors. Acta Oncologica.  ISSN 0284-186X.  51(5), s 603- 609 . doi: 10.3109/0284186X.2012.658115
  • Haakensen, Vilde Drageset; Bjøro, Trine; Luders, Torben; Riis, Margit; Bukholm, Ida Rashida Khan; Kristensen, Vessela N.; Troester, Melissa A; Holmen, Marit Muri; Ursin, Giske; Børresen-Dale, Anne-Lise & Helland, Åslaug (2011). Serum estradiol levels associated with specific gene expression patterns in normal breast tissue and in breast carcinomas. BMC Cancer.  ISSN 1471-2407.  11 . doi: 10.1186/1471-2407-11-332
  • Haakensen, Vilde Drageset; Lingjærde, Ole Christian; Luders, Torben; Riis, Margit; Prat, Aleix; Troester, Melissa A; Holmen, Marit Muri; Frantzen, Jan Ole; Romundstad, Linda; Navjord, Dina; Bukholm, Ida Rashida Khan; Johannesen, Tom Børge; Perou, Charles M; Ursin, Giske; Kristensen, Vessela N.; Børresen-Dale, Anne-Lise & Helland, Åslaug (2011). Gene expression profiles of breast biopsies from healthy women identify a group with claudin-low features. BMC Medical Genomics.  ISSN 1755-8794.  4 . doi: 10.1186/1755-8794-4-77 Show summary
  • Helland, Åslaug; Anglesio, Michael S.; George, Joshy; Covin, Prue A.; Johnstone, Cameron N.; House, Colin M.; Sheppard, Karen E.; Etemadmoghadam, Dariush; Melnyk, Nataliya; Rustgi, Anyl K.; Phillips, Wayne A.; Johnsen, Hilde; Holm, Ruth; Kristensen, Gunnar S Balle; Birrer, Michael J.; Pearson, Richard B.; Børresen-Dale, Anne-Lise; Huntsman, David G.; deFazio, Anna; Creighton, Chad J.; Smyth, Gordon K. & Bowtell, David D.L. (2011). Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers. PLOS ONE.  ISSN 1932-6203.  6(4) . doi: 10.1371/journal.pone.0018064
  • Helland, Åslaug; Skaug, Hege Marian; Kleinberg, Lilach; Lund-Iversen, Marius; Rud, Ane Kristine Kongsgaard; Fleischer, Thomas; Sagerup, Camilla Maria Troøien; Solberg, Steinar; Jørgensen, Lars Hilmar; Ariansen, Sarah Louise & Brustugun, Odd Terje (2011). EGFR Gene Alterations in a Norwegian Cohort of Lung Cancer Patients Selected for Surgery. Journal of Thoracic Oncology.  ISSN 1556-0864.  6(5), s 947- 950 . doi: 10.1097/JTO.0b013e31820db209
  • Knudtsen, Ingerid Skjei; Rødal, Jan; Brustugun, Odd Terje; Helland, Åslaug; Skretting, Arne & Malinen, Eirik (2011). Dynamic respiratory gated (18)FDG-PET of lung tumors - a feasibility study. Acta Oncologica.  ISSN 0284-186X.  50(6), s 889- 896 . doi: 10.3109/0284186X.2011.583266

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  • Ikdahl, Tone; Børresen-Dale, Anne-Lise; Helland, Åslaug & Haakensen, Vilde Drageset (2012). Tumorbiologi. Gyldendal Norsk Forlag A/S.  ISBN 978-82-05-42550-7.

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  • Abravan, Azadeh; Eide, Hanne Astrid; Helland, Åslaug & Malinen, Eirik (2019). Radiotherapy-related lymphopenia in patients with advanced non-small cell lung cancer receiving palliative radiotherapy.
  • Berg, Janna; Lindberg, Morten; Bengtson, May-Bente; Brustugun, Odd Terje & Helland, Åslaug (2019). The Neutrophil and Platelet to Lymphocyte Ratios and Glasgow Prognostic Score as a Predictor for Relapse After Stereotactic Radiation for Lung Cancer. Journal of Thoracic Oncology.  ISSN 1556-0864.  14, s S1101 . doi: 10.1016/j.jtho.2019.08.2457
  • Abravan, Azadeh; Eide, Hanne Astrid; Løndalen, Ayca; Helland, Åslaug & Malinen, Eirik (2018). Reduction in the bone marrow 18F-FDG uptake during thoracic radiotherapy of lung cancer. Radiotherapy and Oncology.  ISSN 0167-8140.  127, s 1164- 1164
  • Helland, Åslaug (2018). Banebrytende basalforskning. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  138(20) . doi: 10.4045/tidsskr.18.0802
  • Knudtsen, Ingerid Søberg Skjei; Eide, Hanne Astrid; Løndalen, Ayca; Abravan, Azadeh; Bogsrud, Trond; Sprauten, Mette; Brustugun, Odd Terje; Helland, Åslaug & Malinen, Eirik (2017). 18FDG-PET/CT for assessing short-term therapy response of advanced non-small cell lung cancer patients.
  • Abravan, Azadeh; Knudtsen, Ingerid Skjei; Eide, Hanne Astrid; Helland, Åslaug; van Luijk, Peter & Malinen, Eirik (2016). PET based response assessment of lung toxicity - assessment of two approaches for dose response. Radiotherapy and Oncology.  ISSN 0167-8140.  119, s 450- 450
  • Christoffersen, Thoralf; Helland, Åslaug; Engebråten, Olav; Straume, Oddbjørn & Guren, Tormod Kyrre (2016). Signalhemmere, I: Olav Dahl; Gustav Lehne & Thoralf Christoffersen (red.),  Medikamentell kreftbehandling - Cytostatikaboken 8. utgave 2016.  Avdeling for farmakologi, Universitetet i Oslo.  ISBN 978-82-992331-4-9.  Kapittel 17.  s 282 - 328
  • Abravan, Azadeh; Knudtsen, Ingerid Skjei; Eide, Hanne; Brustugun, Odd Terje; Helland, Åslaug & Malinen, Eirik (2015). FDG-PET response in the normal lung for lung cancer patients receiving fractionated radiotherapy and erlotinib. Radiotherapy and Oncology.  ISSN 0167-8140.  115, s s634- s634 . doi: 10.1016/S0167-8140(15)41159-4
  • Abravan, Azadeh; Knudtsen, Ingerid Skjei; Eide, Hanne Astrid; Brustugun, Odd Terje; Helland, Åslaug & Malinen, Eirik (2014). Assessing glycolytic response in normal tissues following fractionated radiotherapy.
  • Abravan, Azadeh; Knudtsen, Ingerid Skjei; Eide, Hanne; Brustugun, Odd Terje; Helland, Åslaug & Malinen, Eirik (2014). Monitoring changes in lung glucose metabolism for patients with lung cancer receiving thoracic irradiation. Radiotherapy and Oncology.  ISSN 0167-8140.  111, s 664- 664
  • Knudtsen, Ingerid Skjei; Eide, Hanne; Løndalen, Ayca Muftuler; Bogsrud, Trond Velde; Brustugun, Odd Terje; Helland, Åslaug & Malinen, Eirik (2014). 18FDG-PET/CT evaluation of non-small cell lung cancer patients receiving radiotherapy and erlotinib. Radiotherapy and Oncology.  ISSN 0167-8140.  111, s 667- 667
  • Baumbusch, Lars Oliver; Helland, Åslaug; Wang, Yun; Liestøl, Knut; Schaner, Marci; Holm, Ruth; Etemadmoghadam, Dariush; Alsop, Kathryn; Brown, Patrick; Cancer Study Group, Australian Ovarian; Mitchell, Gillian; Fereday, Sian; DeFazio, Anna; Bowtell, David DL; Kristensen, Gunnar B.; Lingjærde, Ole Christian & Børresen-Dale, Anne-Lise (2012). High levels of genomic aberrations in serous ovarian cancers are associated with better survival.
  • Berg, Arne; Brustugun, Odd Terje; Lund-Iversen, Marius & Helland, Åslaug (2011). Palmar Bullous Blistering Induced by Erlotinib. Journal of Thoracic Oncology.  ISSN 1556-0864.  6(5), s 954- 954 . doi: 10.1097/JTO.0b013e318211136b
  • Haakensen, Vilde Drageset & Helland, Åslaug (2011). Biology of the normal breast : relation to mammographic density and risk of breast cancer. Series of dissertations submitted to the Faculty of Medicine, University of Oslo. 1137.
  • Knudtsen, Ingerid Skjei; Rødal, Jan; Brustugun, Odd Terje; Helland, Åslaug; Skretting, Arne & Malinen, Eirik (2011). DYNAMIC RESPIRATORY GATED FDG-PET OF LUNG CANCER FOR RADIOTHERAPY PLANNING AND TUMOR CHARACTERIZATION. Radiotherapy and Oncology.  ISSN 0167-8140.  99, s 431- 431
  • Nordgård, Oddmund; Ulas, Mona; Singh, Gurpartap; Fleischer, Thomas; Camilla, Sagerup; Smaaland, Rune; Brustugun, Odd Terje & Helland, Åslaug (2011). Molecular tumour markers in regional lymph nodes and blood from patients undergoing surgery for non-small cell lung cancer.

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Published Sep. 23, 2016 12:16 PM - Last modified Sep. 14, 2017 1:25 PM