Espen Melum

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Visiting address Sognsvannsveien 20 OUS Rikshospitalet 0372 Oslo
Postal address Postboks 4950 Nydalen OUS, Rikshospitalet 0424 Oslo

Publications

  • Chung, Brian K.; Øgaard, Jonas; Reims, Henrik Mikael; Karlsen, Tom Hemming & Melum, Espen (2022). Spatial transcriptomics identifies enriched gene expression and cell types in human liver fibrosis. Hepatology communications.. ISSN 2471-254X. 6(9), p. 2538–2550. doi: 10.1002/hep4.2001.
  • Valestrand, Laura Cecilie; Zheng, Fei; Hansen, Simen Hyll; Øgaard, Jonas; Hov, Johannes Espolin Roksund & Björkström, Niklas K. [Show all 9 contributors for this article] (2022). Bile from Patients with Primary Sclerosing Cholangitis Contains Mucosal-Associated Invariant T-Cell Antigens. American Journal of Pathology. ISSN 0002-9440. 192(4), p. 629–641. doi: 10.1016/j.ajpath.2021.12.008.
  • Yu, Jingru; Refsum, Erle; Helsingen, Lise Mørkved; Folseraas, Trine; Ploner, Alexander & Wieszczy, Paulina [Show all 15 contributors for this article] (2022). Risk of hepato-pancreato-biliary cancer is increased by primary sclerosing cholangitis in patients with inflammatory bowel disease: A population-based cohort study. United European Gastroenterology journal. ISSN 2050-6406. 10(2), p. 212–224. doi: 10.1002/ueg2.12204.
  • Tønnessen, Theis; Melleby, Arne Olav; Hauge-Iversen, Ida Marie; Espe, Emil Knut Stenersen; Ahmed, Muhammad Shakil & Ueland, Thor [Show all 12 contributors for this article] (2022). Impact of delayed type hypersensitivity arthritis on development of heart failure by aortic constriction in mice. PLOS ONE. ISSN 1932-6203. 17(1). doi: 10.1371/journal.pone.0262821. Full text in Research Archive
  • Sampaziotis, Fotios; Muraro, Daniele; Tysoe, Olivia C.; Sawiak, Stephen; Beach, Timothy E. & Godfrey, Edmund M. [Show all 40 contributors for this article] (2021). Cholangiocyte organoids can repair bile ducts after transplantation in the human liver. Science. ISSN 0036-8075. 371(6531), p. 839–846. doi: 10.1126/science.aaz6964.
  • Zimmer, Christine L.; Filipovic, Iva; Cornillet, Martin; O’Rourke, Colm J.; Berglin, Lena & Jansson, Hannes [Show all 20 contributors for this article] (2021). Mucosal-associated invariant T-cell tumor infiltration predicts long-term survival in cholangiocarcinoma. Hepatology. ISSN 0270-9139. doi: 10.1002/hep.32222. Full text in Research Archive
  • Jiang, Xiaojun; Bergquist, Annika; Löscher, Britt-Sabina; Venkatesh, Geetha; Mold, Jeff E. & Holm, Kristian [Show all 15 contributors for this article] (2021). A heterozygous germline CD100 mutation in a family with primary sclerosing cholangitis. Science Translational Medicine. ISSN 1946-6234. 13(582). doi: 10.1126/scitranslmed.abb0036.
  • Hausken, John; Haugaa, Håkon; Hagness, Morten; Line, Pål-Dag; Melum, Espen & Tønnessen, Tor Inge (2021). Thoracic Epidural Analgesia for Postoperative Pain Management in Liver Transplantation: A 10-year Study on 685 Liver Transplant Recipients. Transplantation direct. ISSN 2373-8731. 7(2), p. 1–6. doi: 10.1097/TXD.0000000000001101. Full text in Research Archive
  • Harrison, Sean; Siller, Richard; Tanaka, Yoshiaki; Xiang, Yangfei; Patterson, Benjamin & Kempf, Henning [Show all 29 contributors for this article] (2020). Scalable production of tissue-like vascularised liver organoids from human PSCs. BioRxiv. ISSN 0362-4331. doi: 10.1101/2020.12.02.406835.
  • Lissing, Mattias; Nowak, Greg; Adam, René; Karam, Vincent; Boyd, Alexander & Gouya, Laurent [Show all 21 contributors for this article] (2020). Liver Transplantation for Acute Intermittent Porphyria. Liver transplantation. ISSN 1527-6465. doi: 10.1002/lt.25959. Full text in Research Archive
  • Louwe, Maria Cornelia; Olsen, Maria Belland; Kaasbøll, Ole Jørgen; Yang, Kuan; Fosshaug, Linn Elisabeth Lillerud & Alfsnes, Katrine [Show all 25 contributors for this article] (2020). Absence of NLRP3 Inflammasome in Hematopoietic Cells Reduces Adverse Remodeling After Experimental Myocardial Infarction. JACC: Basic to Translational Science. ISSN 2452-302X. 5(12), p. 1210–1224. doi: 10.1016/j.jacbts.2020.09.013. Full text in Research Archive
  • Valestrand, Laura Cecilie; Berntsen, Natalie Lie; Fei, Zheng; Schrumpf, Erik; Hansen, Simen Hyll & Karlsen, Tom Hemming [Show all 10 contributors for this article] (2020). Lipid antigens in bile from patients with chronic liver diseases activate natural killer T cells. Clinical and Experimental Immunology. ISSN 0009-9104. doi: 10.1111/cei.13541. Full text in Research Archive
  • Melum, Espen; Jiang, Xiaojun; Baker, Kirsti B; Macedo, M Fatima; Fritsch, Jürgen & Dowds, C Marie [Show all 21 contributors for this article] (2019). Control of CD1d-restricted antigen presentation and inflammation by sphingomyelin. Nature Immunology. ISSN 1529-2908. 20(12), p. 1644–1655. doi: 10.1038/s41590-019-0504-0. Full text in Research Archive
  • Tysoe, Olivia C.; Justin, Alexander W.; Brevini, Teresa; Chen, Si Emma; Mahbubani, Krishnaa T. & Frank, Anna Katharina [Show all 12 contributors for this article] (2019). Isolation and propagation of primary human cholangiocyte organoids for the generation of bioengineered biliary tissue. Nature Protocols. ISSN 1754-2189. 14, p. 1884–1925. doi: 10.1038/s41596-019-0168-0.
  • Maroni, L.; Pinto, C; Giordano, Debora M; Saccomanno, Stefania; Banales, Jesus M. & Spallacci, D [Show all 18 contributors for this article] (2018). Ageing-related expression of Twinfilin-1 regulates cholangiocyte biological response to injury. Hepatology. ISSN 0270-9139. doi: 10.1002/hep.30466.
  • Pihlstrøm, Hege; Mjøen, Geir; Mucha, S; Franke, Andre; Jardine, A & Fellstrom, B [Show all 9 contributors for this article] (2018). Genetic markers associated with long-term cardiovascular outcome in kidney transplant recipients. American Journal of Transplantation. ISSN 1600-6135. doi: 10.1111/ajt.15191.
  • Holmer, Magnus; Melum, Espen; Isoniemi, Helena; Ericzon, Bo-Göran; Castedal, Maria & Nordin, Arno [Show all 12 contributors for this article] (2018). Nonalcoholic fatty liver disease is an increasing indication for liver transplantation in the Nordic countries. Liver international (Print). ISSN 1478-3223. 38(11), p. 2082–2090. doi: 10.1111/liv.13751.
  • Thorgersen, Ebbe Billmann; Melum, Espen; Folseraas, Trine; Larsen, Stein Gunnar & Line, Pål Dag (2018). Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for pseudomyxoma peritonei in a liver-transplanted patient: A case report. World Journal of Surgical Oncology (WJSO). ISSN 1477-7819. 16:180, p. 1–5. doi: 10.1186/s12957-018-1482-7. Full text in Research Archive
  • Berntsen, Natalie Lie; Fosby, Bjarte; Tan, Corey; Reims, Henrik Mikael; Øgaard, Jonas & Jiang, Xiaojun [Show all 12 contributors for this article] (2018). Natural killer T cells mediate inflammation in the bile ducts. Mucosal Immunology. ISSN 1933-0219. p. 1–9. doi: 10.1038/s41385-018-0066-8.
  • Sampaziotis, Fotios; Justin, Alexander W.; Tysoe, Olivia C.; Sawiak, Stephen; Godfrey, Edmund M. & Upponi, Sara S. [Show all 43 contributors for this article] (2017). Reconstruction of the mouse extrahepatic biliary tree using primary human extrahepatic cholangiocyte organoids. Nature Medicine. ISSN 1078-8956. 23(8), p. 954–963. doi: 10.1038/nm.4360.
  • Chellappa, Stalin ; Hugenschmidt, Harald; Hagness, Morten; Subramani, Saranya; Melum, Espen & Line, Pål Dag [Show all 10 contributors for this article] (2017). CD8+ T Cells That Coexpress RORγt and T-bet Are Functionally Impaired and Expand in Patients with Distal Bile Duct Cancer. Journal of Immunology. ISSN 0022-1767. 198(4), p. 1729–1739. doi: 10.4049/jimmunol.1600061.
  • Alberts, R; de Vries, EMG; Goode, EC; Jiang, Xiaojun; Sampaziotis, Fotios & Rombouts, K [Show all 50 contributors for this article] (2017). Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis. Gut. ISSN 0017-5749. 67(8), p. 1517–1524. doi: 10.1136/gutjnl-2016-313598.
  • Berntsen, Natalie Lie; Fosby, Bjarte; Valestrand, Laura Cecilie; Tan, Corey; Reims, Henrik Mikael & Schrumpf, Elisabeth [Show all 9 contributors for this article] (2017). Establishment of a surgical bile duct injection technique giving direct access to the bile ducts for studies of the murine biliary tree. American Journal of Physiology - Gastrointestinal and Liver Physiology. ISSN 0193-1857. 314(3), p. G349–G359. doi: 10.1152/ajpgi.00124.2017.
  • Henriksen, Eva Kristine Klemsdal; Viken, Marte K; Wittig, Michael; Holm, Kristian; Folseraas, Trine & Mucha, Sören [Show all 29 contributors for this article] (2017). HLA haplotypes in primary sclerosing cholangitis patients of admixed and non-European ancestry. HLA. ISSN 2059-2302. 90(4), p. 228–233. doi: 10.1111/tan.13076.
  • Jiang, Xiaojun; Björkström, Niklas K. & Melum, Espen (2017). Intact CD100-CD72 interaction necessary for TCR-induced T cell proliferation. Frontiers in Immunology. ISSN 1664-3224. 8:765. doi: 10.3389/fimmu.2017.00765.
  • Landskron, Johannes; Kraggerud, Sigrid M.; Wik, Elisabeth; Dørum, Anne; Bjørnslett, Merete Pauline & Melum, Espen [Show all 11 contributors for this article] (2017). C77G in PTPRC (CD45) is no risk allele for ovarian cancer, but associated with less aggressive disease. PLOS ONE. ISSN 1932-6203. 12:e0182030(7), p. 1–12. doi: 10.1371/journal.pone.0182030. Full text in Research Archive
  • Vesterhus, Mette; Holm, Anders; Hov, Johannes Espolin Roksund; Nygård, Ståle; Schrumpf, Erik & Melum, Espen [Show all 23 contributors for this article] (2017). Novel serum and bile protein markers predict primary sclerosing cholangitis disease severity and prognosis. Journal of Hepatology. ISSN 0168-8278. 66(6), p. 1214–1222. doi: 10.1016/j.jhep.2017.01.019.
  • Meijerink, Hinta; White, Richard; Løvlie, Astrid Louise; De Blasio, Birgitte Freiesleben; Dalgard, Olav & Amundsen, Ellen Johanna [Show all 8 contributors for this article] (2017). Modelling the burden of hepatitis C infection among people who inject drugs in Norway, 1973–2030. BMC Infectious Diseases. ISSN 1471-2334. 17. doi: 10.1186/s12879-017-2631-2. Full text in Research Archive
  • Schrumpf, Elisabeth; Jiang, Xiaojun; Zeissig, Sebastian; Pollheimer, Marion J.; Anmarkrud, Jarl Andreas & Tan, Corey [Show all 10 contributors for this article] (2017). The role of natural killer T cells in a mouse model with spontaneous bile duct inflammation. Physiological Reports. ISSN 2051-817X. 5:e13117(4), p. 1–12. doi: 10.14814/phy2.13117.
  • Schrumpf, Elisabeth; Kummen, Martin; Valestrand, Cecilie; Greiner, Thomas U; Holm, Kristian & Arulampalam, Velmurugesam [Show all 13 contributors for this article] (2017). The gut microbiota contributes to a mouse model of spontaneous bile duct inflammation. Journal of Hepatology. ISSN 0168-8278. 66(2), p. 382–389. doi: 10.1016/j.jhep.2016.09.020. Full text in Research Archive
  • Maroni, Luca; Agostinelli, Laura; Saccomanno, Stefania; Pinto, Claudio; Giordano, Debora M & Rychilcki, Chiara [Show all 14 contributors for this article] (2017). Nlrp3 activation induces Il-18 synthesis and affects the epithelial barrier function in reactive cholangiocytes. American Journal of Pathology. ISSN 0002-9440. 187(2), p. 366–376. doi: 10.1016/j.ajpath.2016.10.010.
  • Henriksen, Eva Kristine Klemsdal; Jørgensen, Kristin Kaasen; Kaveh, Fatemeh; Holm, Kristian; Hamm, David & Olweus, Johanna [Show all 14 contributors for this article] (2017). Gut and liver T-cells of common clonal origin in primary sclerosing cholangitis-inflammatory bowel disease. Journal of Hepatology. ISSN 0168-8278. 66(1), p. 116–122. doi: 10.1016/j.jhep.2016.09.002.
  • Gunasekaran, Stalin Chellappa; Hugenschmidt, Harald; Hagness, Morten; Subramani, Saranya; Melum, Espen & Line, Pål Dag [Show all 10 contributors for this article] (2017). CD8+ T cells that coexpress ROR?t and T-bet are functionally impaired and expand in patients with distal bile duct cancer. Journal of Immunology. ISSN 0022-1767. 198(4), p. 1729–1739. doi: 10.4049/jimmunol.1600061.
  • Vesterhus, Mette & Melum, Espen (2016). Prognostic biomarkers and surrogate end points in PSC. Liver international (Print). ISSN 1478-3223. 36(12), p. 1748–1751. doi: 10.1111/liv.13216.
  • Ji, Sun-Gou; Juran, Brian D.; Mucha, Sören; Folseraas, Trine; Jostins, Luke & Melum, Espen [Show all 39 contributors for this article] (2016). Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease. Nature Genetics. ISSN 1061-4036. 49(20), p. 269–273. doi: 10.1038/ng.3745.
  • Pihlstrøm, Hege; Mjøen, Geir; Mucha, S; Haraldsen, Guttorm; Franke, A & Jardine, A [Show all 9 contributors for this article] (2016). Single Nucleotide Polymorphisms and Long-Term Clinical Outcome in Renal Transplant Patients: A Validation Study. American Journal of Transplantation. ISSN 1600-6135. 17(2), p. 528–533. doi: 10.1111/ajt.13995.
  • Liaskou, Evaggelia; Henriksen, Eva Kristine Klemsdal; Holm, Kristian; Kaveh, Fatemeh; Hamm, D & Fear, Janine [Show all 13 contributors for this article] (2016). High-throughput T-cell receptor sequencing across chronic liver diseases reveals distinct disease-associated repertoires. Hepatology. ISSN 0270-9139. 63(5), p. 1608–1619. doi: 10.1002/hep.28116.
  • Zeissig, Sebastian; Petersen, Britt-Sabina; Tomczak, Michal; Melum, Espen; Huc-Claustre, Emilie & Dougan, Stephanie K. [Show all 14 contributors for this article] (2015). Early-onset Crohn's disease and autoimmunity associated with a variant in CTLA-4. Gut. ISSN 0017-5749. 64(12), p. 1889–1897. doi: 10.1136/gutjnl-2014-308541.
  • Schrumpf, Elisabeth; Tan, Corey; Karlsen, Tom Hemming; Sponheim, Jon; Björkström, Niklas K. & Sundnes, Olav [Show all 16 contributors for this article] (2015). The biliary epithelium presents antigens to and activates natural killer T cells. Hepatology. ISSN 0270-9139. 62(4), p. 1249–1259. doi: 10.1002/hep.27840.
  • Sampaziotis, Fotios; De Brito, Miguel Cardoso; Madrigal, Pedro; Bertero, Alessandro; Saeb-Parsy, Kourosh & Soares, Filipa A.C. [Show all 17 contributors for this article] (2015). Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation. Nature Biotechnology. ISSN 1087-0156. 33(8), p. 845–852. doi: 10.1038/nbt.3275.
  • Olin, Per Bertil Mårten; Hausken, John; Foss, Aksel; Karlsen, Tom Hemming; Melum, Espen & Haugaa, Håkon (2015). Continuous molecular adsorbent recirculating system treatment in 69 patients listed for liver transplantation. Scandinavian Journal of Gastroenterology. ISSN 0036-5521. 50(9), p. 1127–1134. doi: 10.3109/00365521.2015.1027262.
  • Fosby, Bjarte; Melum, Espen; Bjøro, Kristian; Bennet, William; Rasmussen, Allan & Andersen, Ina Riise [Show all 30 contributors for this article] (2015). Liver transplantation in the Nordic countries-An intention to treat and post-transplant analysis from the Nordic Liver Transplant Registry 1982-2013. Scandinavian Journal of Gastroenterology. ISSN 0036-5521. 50(6), p. 797–808. doi: 10.3109/00365521.2015.1036359.
  • Huang, Yu-Hwa; Zhu, Chen; Kondo, Yasuyuki; Anderson, Ana C.; Gandhi, Amit & Russell, Andrew [Show all 24 contributors for this article] (2015). CEACAM1 regulates TIM-3-mediated tolerance and exhaustion. Nature. ISSN 0028-0836. 517, p. 386–390. doi: 10.1038/nature13848.
  • Næss, Sigrid; Lie, Benedicte Alexandra; Melum, Espen; Olsson, Marita; Hov, Johannes Espolin Roksund & Croucher, PJP [Show all 15 contributors for this article] (2014). Refinement of the MHC risk map in a Scandinavian primary sclerosing cholangitis population. PLOS ONE. ISSN 1932-6203. 9:e0114486(12). doi: 10.1371/journal.pone.0114486.
  • Eskesen, Arne N; Bjøro, Kristian; Aandahl, Einar Martin; Line, Pål Dag & Melum, Espen (2014). Low use of surveillance and early diagnosis of hepatocellular carcinoma in Norway-A population-based cohort study. Cancer Epidemiology. ISSN 1877-7821. 38(6), p. 741–747. doi: 10.1016/j.canep.2014.10.005.
  • Fosby, Bjarte; Næss, Sigrid; Hov, Johannes Espolin Roksund; Traherne, James; Boberg, Kirsten Muri & Trowsdale, John [Show all 12 contributors for this article] (2014). HLA variants related to primary sclerosing cholangitis influence rejection after liver transplantation. World Journal of Gastroenterology (WJG). ISSN 1007-9327. 20(14), p. 3986–4000. doi: 10.3748/wjg.v20.i14.3986.
  • Henriksen, Eva Kristine Klemsdal; Melum, Espen & Karlsen, Tom Hemming (2014). Update on primary sclerosing cholangitis genetics. Current Opinion in Gastroenterology. ISSN 0267-1379. 30(3), p. 310–319. doi: 10.1097/MOG.0000000000000052.
  • Fickert, Peter; Pollheimer, Marion J.; Beuers, Ulrich; Lackner, Carolin; Hirschfield, Gideon & Housset, Chantal [Show all 16 contributors for this article] (2014). Characterization of animal models for primary sclerosing cholangitis (PSC). Journal of Hepatology. ISSN 0168-8278. 60(6), p. 1290–1303. doi: 10.1016/j.jhep.2014.02.006.
  • Næss, Sigrid; Björnsson, Einar; Anmarkrud, Jarl Andreas; Al Mamari, Said; Juran, Brian D. & Lazaridis, Konstantinos N. [Show all 15 contributors for this article] (2014). Small duct primary sclerosing cholangitis without inflammatory bowel disease is genetically different from large duct disease. Liver international (Print). ISSN 1478-3223. 34(10), p. 1488–1495. doi: 10.1111/liv.12492.
  • Liu, Jimmy Z.; Hov, Johannes Espolin Roksund; Folseraas, Trine; Ellinghaus, E; Rushbrook, SM & Doncheva, NT [Show all 84 contributors for this article] (2013). Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis. Nature Genetics. ISSN 1061-4036. 45(6), p. 670–675. doi: 10.1038/ng.2616.
  • Forster, Michael; Forster, Peter; Elsharawy, Abdou; Hemmrich, Georg; Kreck, Benjamin & Wittig, Michael [Show all 18 contributors for this article] (2013). From next-generation sequencing alignments to accurate comparison and validation of single-nucleotide variants: the pibase software. Nucleic Acids Research (NAR). ISSN 0305-1048. 41(1). doi: 10.1093/nar/gks836.
  • Ellinghaus, David; Folseraas, Trine; Holm, Kristian; Ellinghaus, Eva; Melum, Espen & Balschun, Tobias [Show all 37 contributors for this article] (2013). Genome-wide association analysis in Primary sclerosing cholangitis and ulcerative colitis identifies risk loci at GPR35 and TCF4. Hepatology. ISSN 0270-9139. 58(3), p. 1074–1083. doi: 10.1002/hep.25977.
  • Eskesen, Arne N; Melum, Espen; Moghaddam, Amir; Bjøro, Kristian; Verbaan, Hans & Ring-Larsen, Helmer [Show all 7 contributors for this article] (2012). Genetic variants at the ITPA locus protect against ribavirin-induced hemolytic anemia and dose reduction in an HCV G2/G3 cohort. European Journal of Gastroenterology and Hepathology. ISSN 0954-691X. 24(8), p. 890–896. doi: 10.1097/MEG.0b013e3283546efd.
  • Srivastava, Brijesh; Mells, George F.; Cordell, Heather J.; Muriithi, Agnes; Brown, Matthew & Ellinghaus, Eva [Show all 13 contributors for this article] (2012). Fine mapping and replication of genetic risk loci in primary sclerosing cholangitis. Scandinavian Journal of Gastroenterology. ISSN 0036-5521. 47(7), p. 820–826. doi: 10.3109/00365521.2012.682090.
  • Folseraas, Trine; Melum, Espen; Rausch, Philipp; Juran, Brian D.; Ellinghaus, Eva & Shiryaev, Alexey [Show all 40 contributors for this article] (2012). Extended analysis of a genome-wide association study in primary sclerosing cholangitis detects multiple novel risk loci. Journal of Hepatology. ISSN 0168-8278. 57(2), p. 366–375. doi: 10.1016/j.jhep.2012.03.031.
  • Folseraas, Trine; Melum, Espen; Franke, Andre & Karlsen, Tom Hemming (2011). Genetics in primary sclerosing cholangitis. Baillière's Best Practice & Research : Clinical Gastroenterology. ISSN 1521-6918. 25(6), p. 713–726. doi: 10.1016/j.bpg.2011.09.010.
  • Folseraas, Trine; Melum, Espen; Franke, Andre & Karlsen, Tom Hemming (2011). Best Practice & Research Clinical Gastroenterology. Baillière's Best Practice & Research : Clinical Gastroenterology. ISSN 1521-6918. 25(6), p. 713–726. doi: 10.1016/j.bpg.2011.09.010.
  • Melum, Espen; Franke, Andre; Schramm, Christoph; Weismüller, Tobias J.; Gotthardt, Daniel & Offner, Felix A. [Show all 43 contributors for this article] (2011). Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci. Nature Genetics. ISSN 1061-4036. 43(1), p. 17–19. doi: 10.1038/ng.728.
  • Moghaddam, Amir; Melum, Espen; Reinton, Nils; Ring-Larsen, Helmer; Verbaan, Hans & Bjøro, Kristian [Show all 7 contributors for this article] (2011). IL28B Genetic Variation and Treatment Response in Patients with Hepatitis C Virus Genotype 3 Infection. Hepatology. ISSN 0270-9139. 53(3), p. 746–754. doi: 10.1002/hep.24154.
  • Melum, Espen; May, Sandra; Schilhabel, Markus B.; Thomsen, Ingo; Karlsen, Tom Hemming & Rosenstiel, Philip [Show all 8 contributors for this article] (2010). SNP Discovery Performance of Two Second-Generation Sequencing Platforms in the NOD2 Gene Region. Human Mutation. ISSN 1059-7794. 31(7), p. 875–885. doi: 10.1002/humu.21276.
  • Holm, Kristian; Melum, Espen; Franke, Andre & Karlsen, Tom Hemming (2010). SNPexp - A web tool for calculating and visualizing correlation between HapMap genotypes and gene expression levels. BMC Bioinformatics. ISSN 1471-2105. 11. doi: 10.1186/1471-2105-11-600.
  • Karlsen, Tom Hemming; Melum, Espen & Franke, Andre (2010). The Utility of Genome-Wide Association Studies in Hepatology. Hepatology. ISSN 0270-9139. 51(5), p. 1833–1842. doi: 10.1002/hep.23564.
  • Lorentzen, Åslaug Rudjord; Melum, Espen; Ellinghaus, Eva; Smestad, Cathrine; Mero, Inger-Lise & Aarseth, Jan Harald [Show all 12 contributors for this article] (2010). Association to the Glypican-5 gene in multiple sclerosis. Journal of Neuroimmunology. ISSN 0165-5728. 226(1-2), p. 194–197. doi: 10.1016/j.jneuroim.2010.07.003.
  • Evang, Johan Arild; Borota, Olivera Casar; Melum, Espen; Holm, Ruth; Ramm-Pettersen, Jon-Terje & Bollerslev, Jens [Show all 7 contributors for this article] (2010). HDAC2 expression and variable number of repeats in exon 1 of the HDAC2 gene in corticotroph adenomas. Clinical Endocrinology. ISSN 0300-0664. 73(2), p. 229–235. doi: 10.1111/j.1365-2265.2010.03805.x.
  • Hov, Johannes Espolin Roksund; Keitel, V; Lærdahl, Jon Kristen; Spomer, L; Ellinghaus, E & ElSharawy, A [Show all 36 contributors for this article] (2010). Mutational Characterization of the Bile Acid Receptor TGR5 in Primary Sclerosing Cholangitis. PLOS ONE. ISSN 1932-6203. 5(8). doi: 10.1371/journal.pone.0012403.
  • Karlsen, Tom Hemming; Franke, Andre; Melum, Espen; Kaser, Arthur; Hov, Johannes Espolin Roksund & Balschun, Tobias [Show all 32 contributors for this article] (2010). Genome-Wide Association Analysis in Primary Sclerosing Cholangitis. Gastroenterology. ISSN 0016-5085. 138(3), p. 1102–1111. doi: 10.1053/j.gastro.2009.11.046.
  • Melum, Espen; Karlsen, TH; Schrumpf, Erik; Bergquist, A; Thorsby, Erik & Boberg, Kirsten Muri [Show all 7 contributors for this article] (2008). Cholanglocarcinoma in primary sclerosing cholangitis is associated with NKG2D Polymorphisms. Hepatology. ISSN 0270-9139. 47, p. 90–96. doi: 10.1002/hep.21964.

View all works in Cristin

  • Jiang, Xiaojun & Melum, Espen (2021). The Role of Natural Killer Cells in Nonalcoholic Steatohepatitis: An Ongoing Debate. Cellular and Molecular Gastroenterology and Hepatology (CMGH). ISSN 2352-345X. doi: 10.1016/j.jcmgh.2021.10.006.
  • Paquin-Proulx, Dominic; Greenspun, Benjamin C.; Pasquet, Lise; Strunz, Benedikt; Aleman, Soo & Falconer, Karolin [Show all 12 contributors for this article] (2018). IL13R?2 expression identifies tissue-resident IL-22-producing PLZF+ innate T cells in the human liver. European Journal of Immunology. ISSN 0014-2980. 48(8), p. 1329–1335. doi: 10.1002/eji.201747334.
  • Srivastava, B; Mells, G.; Cordell, H.; Murithii, A.; Brown, M. & Ellinghaus, E [Show all 13 contributors for this article] (2012). FINE MAPPING OF THE IL-2/IL-21 AND IL2RA LOCI IN PRIMARY SCLEROSING CHOLANGITIS. Journal of Hepatology. ISSN 0168-8278. 56, p. S15–S16.
  • Srivastava, B; Mells, George F.; Cordell, H.J.; Muriithi, Agnes; Brown, M. & Ellinghaus, E [Show all 13 contributors for this article] (2012). FINE MAPPING OF THE IL-2/IL-21 AND IL2RA LOCI IN PRIMARY SCLEROSING CHOLANGITIS. Gut. ISSN 0017-5749. 61, p. A212–A213. doi: 10.1136/gutjnl-2012-302514c.70.
  • Fosby, Bjarte; Karlsen, Tom Hemming & Melum, Espen (2012). Recurrence and rejection in liver transplantation for primary sclerosing cholangitis. World Journal of Gastroenterology (WJG). ISSN 1007-9327. 18(1), p. 1–15. doi: 10.3748/wjg.v18.i1.1.
  • Eskesen, Arne N; Melum, Espen; Moghaddam, Amir; Bjøro, K; Verbaan, H & Ring-Larsen, H. [Show all 7 contributors for this article] (2011). GENETIC VARIANTS AT THE ITPA LOCUS PROTECTS AGAINST RIBAVIRIN-INDUCED HEMOLYTIC ANEMIA - A REPLICATION STUDY IN A SCANDINAVIAN HCV G2/G3 COHORT. Journal of Hepatology. ISSN 0168-8278. 54, p. S455–S455.
  • Lorentzen, Åslaug Rudjord; Melum, Espen; Buchert, Eva; SMESTAD, CATHRINE; Mero, Inger-Lise & Aarseth, Jan Harald [Show all 12 contributors for this article] (2010). Trend of association to the Glypican 5 gene region to multiple sclerosis. European Journal of Neurology. ISSN 1351-5101. 17, p. 221–221.
  • Dalgard, Olav; Moghaddam, Amir; Verbaan, Hans; Ring-Larsen, Helmer; Bjøro, Kristian & Melum, Espen (2010). IL28B GENETIC VARIATION AND TREATMENT RESPONSE IN PATIENTS WITH HCV GENOTYPE 3 INFECTION. Hepatology. ISSN 0270-9139. 52(4), p. 751A–751A.
  • Melum, Espen; Karlsen, TH; Bergquist, A; Schrumpf, Erik & Boberg, Kirsten Muri (2008). An interleukin-6 (IL-6) receptor polymorphism affecting serum levels of IL-6 does not increase the risk of cholangiocarcinoma in primary sclerosing cholangitis. American Journal of Gastroenterology. ISSN 0002-9270. 103, p. 1045–1045.
  • Melum, Espen; Buch, Stephan; Schafmayer, Clemens; Kalthoff, Holger; Tepel, Jürgen & Schreiber, Stefan [Show all 8 contributors for this article] (2008). Investigation of cholangiocarcinoma associated NKG2D polymorphisms in colorectal carcinoma. International Journal of Cancer. ISSN 0020-7136. 123(1), p. 241–242. doi: 10.1002/ijc.23517.
  • Melum, Espen & Karlsen, Tom Hemming (2010). From single markers to genome-wide association – A study of Primary Sclerosing Cholangitis genetics. Unipub forlag. ISSN 978-82-8072-614-8.

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Published Mar. 15, 2018 9:30 AM - Last modified Aug. 8, 2018 9:35 AM