Ingrid Agartz

• Aas, Monica; Dieset, Ingrid; Mørch, Ragni Helene; Steen, Nils Eiel; Hope, Sigrun; Reponen, Elina Johanna; Laskemoen, Jannicke F.; Ueland, Thor; Aukrust, Pål; Melle, Ingrid; Agartz, Ingrid & Andreassen, Ole Andreas (2018). Reduced brain-derived neurotrophic factor is associated with childhood trauma experiences and number of depressive episodes in severe mental disorders. Schizophrenia Research.  ISSN 0920-9964. . doi: 10.1016/j.schres.2018.08.007
• Berg, Akiah Ottesen; Jørgensen, Kjetil Nordbø; Nerhus, Mari; Athanasiu, Lavinia; Popejoy, Alice; Bettella, Francesco; Norbom, Linn Christin Bonaventure; Gurholt, Tiril Pedersen; Dahl, Sandra Rinne; Andreassen, Ole Andreas; Djurovic, Srdjan; Agartz, Ingrid & Melle, Ingrid (2018). Vitamin D levels, brain volume, and genetic architecture in patients with psychosis. PLoS ONE.  ISSN 1932-6203.  13(8) . doi: 10.1371/journal.pone.0200250
• Fagerberg, Tomas; Söderman, Erik; Gustavsson, J. Petter; Agartz, Ingrid & Jönsson, Erik Gunnar (2018). Stability of personality traits over a five-year period in Swedish patients with schizophrenia spectrum disorder and non-psychotic individuals: a study using the Swedish universities Scales of Personality. BMC Psychiatry.  ISSN 1471-244X.  18(54) . doi: 10.1186/s12888-018-1617-y Full text in Research Archive.
• Færden, Ann; Lyngstad, Siv Hege; Simonsen, Carmen Elisabeth; Ringen, Petter Andreas; Papsuev, Oleg; Dieset, Ingrid; Andreassen, Ole Andreas; Agartz, Ingrid; Marder, Stephen R. & Melle, Ingrid (2018). Reliability and validity of the self-report version of the apathy evaluation scale in first-episode Psychosis: Concordance with the clinical version at baseline and 12 months follow-up. Psychiatry Research.  ISSN 0165-1781.  267, s 140- 147 . doi: 10.1016/j.psychres.2018.05.065
• Gurholt, Tiril Pedersen; Osnes, Kåre; Nerhus, Mari; Jørgensen, Kjetil Nordbø; Lonning, Vera Louise Hiorth; Berg, Akiah Ottesen; Andreassen, Ole A.; Melle, Ingrid & Agartz, Ingrid (2018). Vitamin D, Folate and the Intracranial Volume in Schizophrenia and Bipolar Disorder and Healthy Controls. Scientific Reports.  ISSN 2045-2322. . doi: 10.1038/s41598-018-29141-y
• Hartberg, Cecilie Bhandari; Lange, Elisabeth Heffermehl; Lagerberg, Trine Vik; Haukvik, Unn Kristin H.; Andreassen, Ole Andreas; Melle, Ingrid & Agartz, Ingrid (2018). Cortical thickness, cortical surface area and subcortical volumes in schizophrenia and bipolar disorder patients with cannabis use. European Neuropsychopharmacology.  ISSN 0924-977X.  28(1), s 37- 47 . doi: 10.1016/j.euroneuro.2017.11.019
• Haukvik, Unn Kristin H.; Tamnes, Christian Krog; Söderman, Erik & Agartz, Ingrid (2018). Neuroimaging hippocampal subfields in schizophrenia and bipolar disorder: A systematic review and meta-analysis. Journal of Psychiatric Research.  ISSN 0022-3956.  104, s 217- 226 . doi: 10.1016/j.jpsychires.2018.08.012
• Hibar, Derrek; Westlye, Lars Tjelta; Doan, Nhat Trung; Jahanshad, Neda; Cheung, J. W.; Ching, Christopher R K; Versace, Amelia; Bilderbeck, A; Uhlmann, Anne; Mwangi, B; Krämer, B; Overs, B; Hartberg, Cecilie Bhandari; Abé, Christoph; Dima, Danai; Grotegerd, Dominik; Sprooten, Emma; Bøen, Erlend; Jimenez, Enrique; Howells, Fleur M.; Delvecchio, G; Temmingh, H; Starke, J; Almeida, JRC; Goikolea, JM; Houenou, J; Beard, Lauren M.; Rauer, L; Abramovic, Lucija; Bonnin, M.; Ponteduro, MF; Keil, M; Rive, MM; Yao, N; Yalin, N; Najt, P; Rosa, PG; Redlich, Ronny; Trost, S; Hagenaars, Saskia; Fears, SC; Alonso-Lana, S; Van Erp, TGM; Nickson, Thomas; Chaim-Avancini, TM; Meier, TB; Elvsåshagen, Torbjørn; Haukvik, Unn Kristin H.; Lee, Who-Seung; Schene, AH; Lloyd, AJ; Young, AH; Nugent, Allison C; Dale, AM; Pfennig, Andrea; McIntosh, AM; Lafer, Beny; Baune, BT; Ekman, CJ; Zarate, CA; Bearden, CE; Henry, C; Simhandl, Christian; McDonald, C; Bourne, C; Stein, DJ; Wolf, DH; Cannon, DM; Glahn, DC; Veltman, DJ; Pomarol-Clotet, E; Vieta, E; Canales-Rodriguez, EJ; Nery, FG; Duran, FLS; Busatto, GF; Roberts, G; Pearlson, GD; Goodwin, GM; Kugel, H; Whalley, HC; Ruhe, HG; Soares, JC; Fullerton, JM; Rybakowski, JK; Savitz, Jonathan; Chaim, KT; Fatjo-Vilas, Mar; Soeiro-de-Souza, MG; Boks, MP; Zanetti, MV; Otaduy, MCG; Schaufelberger, MS; Alda, Martin; Ingvar, Martin; Phillips, ML; Kempton, MJ; Bauer, M; Landén, M; Lawrence, NS; Van Haren, NEM; Horn, NR; Freimer, NB; Gruber, Oliver; Schofield, PR; Mitchell, PB; Kahn, RS; Lenroot, R; Machado-Vieira, R; Ophoff, RA; Sarró, S; Frangou, Sophia; Satterthwaite, TD; Hajek, Tomas; Dannlowski, Udo; Malt, Ulrik Fredrik; Arolt, Volker; Gattaz, WF; Drevets, WC; Caseras, Xavier; Agartz, Ingrid; Thompson, PM & Andreassen, Ole Andreas (2018). Cortical abnormalities in bipolar disorder: An MRI analysis of 6503 individuals from the ENIGMA Bipolar Disorder Working Group. Molecular Psychiatry.  ISSN 1359-4184.  23, s 932- 942 . doi: 10.1038/mp.2017.73
• Hjärpe, Josefin; Söderman, Erik; Andreou, Dimitrios; Sedvall, Göran C.; Agartz, Ingrid & Jönsson, Erik Gunnar (2018). No major influence of regular tobacco smoking on cerebrospinal fluid monoamine metabolite concentrations in patients with psychotic disorder and healthy individuals. Psychiatry Research.  ISSN 0165-1781.  263, s 30- 34 . doi: 10.1016/j.psychres.2018.02.036
• Kelly, S; Jahanshad, Neda; Zalesky, A; P, Kochunov; Agartz, Ingrid; Alloza, C; Andreassen, Ole Andreas; Arango, C; Banaj, Nerisa; Bouix, S; Bousman, CA; Brouwer, RM; Bruggemann, J; Bustillo, Juan R; Cahn, Wiepke; Calhoun, Vince; Cannon, Dara M; Carr, Vaughan J.; Catts, Stanley V.; Chen, J; Chen, JX; Chen, X; Chiapponi, C; Cho, KK; Ciullo, Valentina; Corvin, A; Crespo-Facorro, Benedicto; Cropley, V; De Rossi, Pietro; Diaz-Caneja, CM; Dickie, EW; Ehrlich, S; Fan, FM; Faskowitz, Joshua; Fatouros-Bergman, Helena; Flyckt, Lena; Ford, JM; Fouche, JP; Fukunaga, Masaki; Gill, M; Glahn, DC; Gollub, Randy L; Goudzwaard, ED; Guo, H; Gur, RE; Gur, RC; Gurholt, Tiril Pedersen; Hashimoto, Ryota; Hatton, SN; Henskens, FA; Hibar, DP; Hickie, IB; Hong, LE; Horacek, Jan; Howells, FM; Hulshoff Pol, Hilleke E; Hyde, CL; Isaev, D; Jablensky, Assen; Jansen, PR; Janssen, J; Jönsson, Erik Gunnar; Jung, LA; Kahn, RS; Kikinis, Z; Liu, K; Klauser, Paul; Knöchel, C; Kubicki, M; Lagopoulos, Jim; Langen, C; Lawrie, Stephen M; Lenroot, R; Lim, KO; Lopez-Jaramillo, Carlos; Lyall, A; Magnotta, V; Mandl, RCW; Mathalon, DH; McCarley, RW; McCarthy-Jones, Simon; McDonald, C; McEwen, S; McIntosh, A; Melicher, T; Mesholam-Gately, RI; Michie, PT; Mowry, Bryan J.; Mueller, BA; Newell, DT; O'donnell, P; Oertel-Knöchel, V; Oestreich, L; Paciga, SA; Pantelis, Christos; Pasternak, O; Pearlson, Godfrey D; Pellicano, GR; Pereira, A; Pineda Zapata, J; Piras, Fabrizio; Potkin, SG; Preda, Adrian; Rasser, PE; Roalf, DR; Roiz, R; Roos, A; Rotenberg, D; Satterthwaite, TD; Savadjiev, P; Schall, Ulrich; Scott, RJ; Seal, ML; Seidman, LJ; Shannon Weickert, C; Whelan, CD; Shenton, ME; Kwon, JS; Spalletta, Gianfranco; Spaniel, F; Sprooten, Emma; Stäblein, M; Stein, DJ; Sundram, S; Tan, Y; Tan, S; Tang, S; Temmingh, HS; Westlye, Lars Tjelta; Tønnesen, Siren; Tordesillas-Gutierrez, Diana; Doan, Nhat Trung; Vaidya, Jatin G.; Van Haren, NEM; Vargas, CD; Vecchio, D; Velakoulis, D; Voineskos, Aristotle N.; Voyvodic, JQ; Wang, Z; Wan, P; Wei, D; Weickert, TW; Whalley, Heather Clare; White, T; Whitford, TJ; Wojcik, JD; XIANG, HUA; Xie, Z; Yamamori, Hidenaga; Yang, F; Yao, N; Zhang, G.; Zhao, J; Van Erp, Theo G M; Turner, J; Thompson, PM & Donohoe, Gary (2018). Widespread white matter microstructural differences in schizophrenia across 4322 individuals: Results from the ENIGMA Schizophrenia DTI Working Group. Molecular Psychiatry.  ISSN 1359-4184.  23, s 1261- 1269 . doi: 10.1038/mp.2017.170
• Kong, Xiang-Zhen; Mathias, Samuel R.; Guadalupe, Tulio; Agartz, Ingrid; Andreassen, Ole Andreas; Bøen, Erlend; Còrdova Palomera, Aldo; Dale, Anders; Doan, Nhat Trung; Elvsåshagen, Torbjørn; Faraone, Stephen V.; Gurholt, Tiril Pedersen; Haavik, Jan; Høvik, Marie Farstad; Hugdahl, Kenneth; Jönsson, Erik Gunnar; Lundervold, Astri; Malt, Ulrik Fredrik; Nerland, Stener; Nordvik, Jan Egil; Plessen, Kerstin J.; Smelror, Runar; van den Heuvel, Odile A; van der Meer, Dennis; Westlye, Lars Tjelta; Glahn, David C.; Franke, Barbara; Crivello, Fabrice; Tzourio-Mazoyer, Nathalie; Fisher, Simon E.; Thompson, Paul M. & Francks, Clyde (2018). Mapping cortical brain asymmetry in 17,141 healthy individuals worldwide via the ENIGMA Consortium.. Proceedings of the National Academy of Sciences of the United States of America.  ISSN 0027-8424.  115(22), s E5154- E5163 . doi: 10.1073/pnas.1718418115
• Maier, Robert M.; Zhu, Zhihong; Lee, Sang Hong; Trzaskowski, Maciej; Ruderfer, Douglas M.; Stahl, Eli A.; Ripke, Stephan; Wray, Naomi R.; Yang, Jian; Visscher, Peter M.; Robinson, Matthew R.; Wang, Yunpeng; Elvsåshagen, Torbjørn; Smeland, Olav Bjerkehagen; Djurovic, Srdjan; Agartz, Ingrid; Mattingsdal, Morten & Melle, Ingrid (2018). Improving genetic prediction by leveraging genetic correlations among human diseases and traits. Nature Communications.  ISSN 2041-1723.  9:989, s 1- 17 . doi: 10.1038/s41467-017-02769-6
• Mørch-Johnsen, Lynn Egeland; Agartz, Ingrid & Jensen, Jimmy Kristian (2018). The Neural Correlates of Negative Symptoms in Schizophrenia: Examples From MRI Literature. Clinical EEG and Neuroscience.  ISSN 1550-0594.  49(1), s 12- 17 . doi: 10.1177/1550059417746214
• Ni, Guiyan; Gratten, Jacob; Wray, Naomi R.; Lee, Sang Hong; Agartz, Ingrid; Djurovic, Srdjan; Joa, Inge; Mattingsdal, Morten; Melle, Ingrid; Andreassen, Ole Andreas & Jönsson, Erik Gunnar (2018). Age at first birth in women is genetically associated with increased risk of schizophrenia. Scientific Reports.  ISSN 2045-2322.  8, s 1- 14 . doi: 10.1038/s41598-018-28160-z
• Van Erp, Theo G.M.; Walton, Esther; Hibar, Derrek; Schmaal, Lianne; Jiang, Wenhao; Glahn, David C.; Pearlson, Godfrey D.; Yao, Nailin; Fukunaga, Masaki; Hashimoto, Ryota; Okada, Naohiro; Yamamori, Hidenaga; Bustillo, Juan R.; Clark, Vincent P.; Agartz, Ingrid; Mueller, Bryon A.; Cahn, Wiepke; de Zwarte, Sonja M.C.; Hulshoff Pol, Hilleke E.; Kahn, René S.; Ophoff, Roel A.; van Haren, Neeltje E.M.; Andreassen, Ole Andreas; Dale, Anders; Doan, Nhat Trung; Gurholt, Tiril Pedersen; Hartberg, Cecilie Bhandari; Haukvik, Unn Kristin H.; Jørgensen, Kjetil Nordbø; Lagerberg, Trine Vik; Melle, Ingrid; Westlye, Lars Tjelta; Gruber, Oliver; Kraemer, Bernd; Richter, Anja; Zilles, David; Calhoun, Vince D.; Crespo-Facorro, Benedicto; Roiz-Santiañez, Roberto; Tordesillas-Gutiérrez, Diana; Loughland, Carmel; Carr, Vaughan J.; Catts, Stanley; Cropley, Vanessa L.; Fullerton, Janice M.; Green, Melissa J.; Henskens, Frans A.; Jablensky, Assen; Lenroot, Rhoshel K.; Mowry, Bryan J.; Michie, Patricia T.; Pantelis, Christos; Quide, Yann; Schall, Ulrich; Scott, Rodney J.; Cairns, Murray J.; Seal, Marc; Tooney, Paul A.; Rasser, Paul E.; Cooper, Gavin; Shannon Weickert, Cynthia; Weickert, Thomas W.; Morris, Derek W.; Hong, Elliot; Kochunov, Peter; Beard, Lauren M.; Gur, Raquel E.; Gur, Ruben C.; Satterthwaite, Theodore D; Wolf, Daniel H.; Belger, Aysenil; Brown, Gregory G.; Ford, Judith M.; Macciardi, Fabio; Mathalon, Daniel H.; O'Leary, Daniel S.; Potkin, Steven G.; Preda, Adrian; Voyvodic, James; Lim, Kelvin O.; McEwen, Sarah; Yang, Fude; Tan, Yunlong; Tan, Shuping; Wang, Zhiren; Fan, Fengmei; Chen, Jingxu; Xiang, Hong; Tang, Shiyou; Guo, Hua; Wan, Ping; Wei, Dong; Bockholt, Henry J.; Ehrlich, Stefan; Wolthusen, Rick P.F.; King, Margaret D.; Shoemaker, Jody M.; Sponheim, Scott R.; De Haan, Lieuwe; Koenders, Laura; Machielsen, Marise W.; van Amelsvoort, Therese; Veltman, Dick J.; Assogna, Francesca; Banaj, Nerisa; de Rossi, Pietro; Iorio, Mariangela; Piras, Fabrizio; Spalletta, Gianfranco; McKenna, Peter J.; Pomarol-Clotet, Edith; Salvador, Raymond; Corvin, Aiden; Donohoe, Gary; Kelly, Sinead; Whelan, Christopher D.; Dickie, Erin W.; Rotenberg, David; Voineskos, Aristotle N.; Ciufolini, Simone; Radua, Joaquim; Dazzan, Paola; Murray, Robin; Reis Marques, Tiago; Simmons, Andrew; Borgwardt, Stefan; Egloff, Laura; Harrisberger, Fabienne; Riecher-Rössler, Anita; Smieskova, Renata; Alpert, Kathryn I.; Wang, Lei; Jönsson, Erik Gunnar; Koops, Sanne; Sommer, Iris Else Clara; Bertolino, Alessandro; Bonvino, Aurora; Di Giorgio, Annabella; Neilson, Emma; Mayer, Andrew R.; Stephen, Julia M.; Kwon, Jun Soo; Yun, Je-Yeon; Cannon, Dara M.; McDonald, Colm; Lebedeva, Irina; Tomyshev, Alexander S.; Akhadov, Tolibjohn; Kaleda, Vasily; Fatouros-Bergman, Helena & Flyckt, Lena (2018). Cortical brain abnormalities in 4474 individuals with schizophrenia and 5098 control subjects via the Enhancing Neuro Imaging Genetics Through Meta Analysis (ENIGMA) Consortium. Biological Psychiatry.  ISSN 0006-3223. . doi: 10.1016/j.biopsych.2018.04.023
• Walton, E; Hibar, Derrek; Van Erp, Theo G M; Potkin, Steven G; Roiz-Santiañez, Roberto; Crespo-Facorro, B; Suarez-Pinilla, Paula; van Haren, Neeltje E.M.; de Zwarte, Sonja M.C.; Kahn, René S; Cahn, Wiepke; Doan, Nhat Trung; Jørgensen, Kjetil Nordbø; Gurholt, Tiril Pedersen; Agartz, Ingrid; Andreassen, Ole Andreas; Westlye, Lars Tjelta; Melle, Ingrid; Berg, Akiah Ottesen; Mørch-Johnsen, Lynn Egeland; Færden, Ann; Flyckt, Lena; Fatouros-Bergman, Helena; Jönsson, Erik Gunnar; Hashimoto, Ryota; Yamamori, Hidenaga; Fukunaga, Masaki; Jahanshad, Neda; De Rossi, Pietro; Piras, Fabrizio; Banaj, Nerisa; Spalletta, Gianfranco; Gur, Raquel E; Gur, Ruben C; Wolf, Daniel H.; Satterthwaite, TD; Beard, Lauren M.; Sommer, Iris E; Koops, Sanne; Gruber, Oliver; Richter, A; Krämer, Bernhard; Kelly, S; Donohoe, G; McDonald, C; Cannon, Dara M; Corvin, Aiden; Gill, M; Di Giorgio, Annabella; Bertolino, A; Lawrie, Stephen M; Nickson, Thomas; Whalley, Heather Clare; Neilson, Emma; Calhoun, Vince D.; Thompson, Paul Murray; Turner, J A & Ehrlich, S (2018). Prefrontal cortical thinning links to negative symptoms in schizophrenia via the ENIGMA consortium. Psychological Medicine.  ISSN 0033-2917.  48(1), s 82- 94 . doi: 10.1017/S0033291717001283
• Aas, Monica; Dieset, Ingrid; Hope, Sigrun; Hoseth, Eva Zsuzsanna; Mørch, Ragni Helene; Reponen, Elina Johanna; Steen, Nils Eiel; Anderssen, Jannicke Fjæra; Ueland, Thor; Aukrust, Pål; Agartz, Ingrid; Andreassen, Ole Andreas & Melle, Ingrid (2017). Childhood maltreatment severity is associated with elevated C-reactive protein and body mass index in adults with schizophrenia and bipolar diagnoses. Brain, behavior, and immunity.  ISSN 0889-1591.  65, s 342- 349 . doi: 10.1016/j.bbi.2017.06.005
• Aas, Monica; Kauppi, Karolina; Brandt, Christine Lycke; Tesli, Martin Steen; Kaufmann, Tobias; Steen, Nils Eiel; Agartz, Ingrid; Westlye, Lars Tjelta; Andreassen, Ole Andreas & Melle, Ingrid (2017). Childhood trauma is associated with increased brain responses to emotionally negative as compared with positive faces in patients with psychotic disorders. Psychological Medicine.  ISSN 0033-2917.  47(4), s 669- 679 . doi: 10.1017/S0033291716002762
• Aas, Monica; Melle, Ingrid; Bettella, Francesco; Djurovic, Srdjan; Le Hellard, Stephanie; Bjella, Thomas; Ringen, Petter Andreas; Lagerberg, Trine Vik; Smeland, Olav Bjerkehagen; Agartz, Ingrid; Andreassen, Ole Andreas & Tesli, Martin Steen (2017). Psychotic patients who used cannabis frequently before illness onset have higher genetic predisposition to schizophrenia than those who did not. Psychological Medicine.  ISSN 0033-2917.  48(1), s 43- 49 . doi: 10.1017/S0033291717001209
• Comasco, Erika; Vumma, Ravi; Toffoletto, Simone; Johansson, Jessica; Flyckt, Lena; Lewander, Tommy; Oreland, Lars; Bjerkenstedt, Lars; Andreou, Dimitrios; Söderman, Erik; Terenius, Lars; Agartz, Ingrid; Jönsson, Erik Gunnar & Venizelos, Nikolaos (2017). Genetic and functional study of L -Type amino acid transporter 1 in schizophrenia. Neuropsychobiology.  ISSN 0302-282X.  74(2), s 96- 103 . doi: 10.1159/000455234
• Doan, Nhat Trung; Engvig, Andreas; Zaske, Krystal; Persson, Karin; Lund, Martina Jonette; Kaufmann, Tobias; Còrdova Palomera, Aldo; Alnæs, Dag; Moberget, Torgeir; Brækhus, Anne; Barca, Maria Lage; Nordvik, Jan Egil; Engedal, Knut; Agartz, Ingrid; Selbæk, Geir; Andreassen, Ole Andreas & Westlye, Lars Tjelta (2017). Distinguishing early and late brain aging from the Alzheimer's disease spectrum: Consistent morphological patterns across independent samples. NeuroImage.  ISSN 1053-8119.  158, s 282- 295 . doi: 10.1016/j.neuroimage.2017.06.070 Full text in Research Archive.
• Doan, Nhat Trung; Kaufmann, Tobias; Bettella, Francesco; Jørgensen, Kjetil Nordbø; Brandt, Christine Lycke; Moberget, Torgeir; Alnæs, Dag; Douaud, Gwenaëlle; Duff, Eugene; Djurovic, Srdjan; Melle, Ingrid; Ueland, Torill; Agartz, Ingrid; Andreassen, Ole Andreas & Westlye, Lars Tjelta (2017). Distinct multivariate brain morphological patterns and their added predictive value with cognitive and polygenic risk scores in mental disorders. NeuroImage: Clinical.  ISSN 2213-1582.  15, s 719- 731 . doi: 10.1016/j.nicl.2017.06.014
• Gupta, Cota Navin; Castro, Eduardo; Rachkonda, Srinivas; Van Erp, Theo G.M.; Potkin, Steven; Ford, Judith Marianne; Mathalon, Daniel H.; Lee, Hyo Jong; Mueller, Bryon A.; Greve, Douglas; Andreassen, Ole Andreas; Agartz, Ingrid; Mayer, Andrew Robert; Stephen, Julia; Jung, Rex E; Bustillo, Juan R; Calhoun, Vince D. & Turner, Jessica A. (2017). Biclustered independent component analysis for complex biomarker and subtype identification from structural magnetic resonance images in schizophrenia. Frontiers in Psychiatry.  ISSN 1664-0640.  8 . doi: 10.3389/fpsyt.2017.00179
• Hibar, Derrek; Adams, Hieab H.H.; Jahanshad, Neda; Chauhan, Ganesh; Stein, Jason L.; Hofer, Edith; Renteriá, Miguel E.; Bis, Joshua C.; Arias-Vasquez, Alejandro; Ikram, M. Kamran; Desrivières, Sylvane; Vernooij, Meike W; Abramovic, Lucija; Alhusaini, Saud; Amin, Najaf; Andersson, Micael; Arfanakis, Konstantinos; Aribisala, Benjamin S.; Armstrong, Nicola J.; Athanasiu, Lavinia; Axelsson, Tomas; Beecham, Ashley H.; Beiser, Alexa; Bernard, Manon; Blanton, Susan H.; Bohlken, Marc M.; Boks, Marco P.; Bralten, Janita; Brickman, Adam M.; Carmichael, Owen; Chakravarty, M. Mallar; Chen, Qiang; Ching, Christopher R.K.; Chouraki, Vincent; Cuellar-Partida, Gabriel; Crivello, Fabrice; Den Braber, Anouk; Doan, Nhat Trung; Ehrlich, Stefan; Giddaluru, Sudheer; Goldman, Aaron L; Gottesman, Rebecca F.; Grimm, Oliver; Griswold, Michael E.; Guadalupe, Tulio; Gutman, Boris A.; Hass, Johanna; Haukvik, Unn Kristin H.; Hoehn, David; Holmes, Avram J.; Hoogman, Martine; Janowitz, Deborah; Jia, Tianye; Jørgensen, Kjetil Nordbø; Karbalai, Nazanin; Kasperaviciute, Dalia; Kim, Sungeun; Klein, Marieke; Kraemer, Bernd; Lee, Phil H.; Liewald, David C.M.; Lopez, Lorna M.; Luciano, Michelle; MacAre, Christine; Marquand, André F.; Matarin, Mar; Mather, Karen A.; Mattheisen, Manuel; McKay, David R.; Milaneschi, Yuri; Muñoz Maniega, Susana; Nho, Kwangsik; Nugent, Allison C.; Nyquist, Paul; Loohuis, Loes M. Olde; Oosterlaan, Jaap; Papmeyer, Martina; Pirpamer, Lukas; Pütz, Benno; Ramasamy, Adaikalavan; Richards, Jennifer S.; Risacher, Shannon L.; Roiz-Santiañez, Roberto; Rommelse, Nanda; Ropele, Stefan; Rose, Emma J.; Royle, Natalie A.; Rundek, Tatjana; Sämann, Philipp G.; Saremi, Arvin; Satizabal, Claudia L.; Schmaal, Lianne; Schork, Andrew J.; Shen, Li; Shin, Jean; Shumskaya, Elena; Smith, Albert V.; Sprooten, Emma; Strike, Lachlan T.; Teumer, Alexander; Tordesillas-Gutierrez, Diana; Toro, Roberto; Trabzuni, Daniah; Trompet, Stella; Vaidya, Dhananjay; Van Der Grond, Jeroen; Van Der Lee, Sven J.; Van Der Meer, Dennis; van Donkelaar, Marjolein M.J.; Van Eijk, Kristel R.; Van Erp, Theo G.M.; Van Rooij, Daan; Walton, Esther; Westlye, Lars Tjelta; Whelan, Christopher D.; Windham, Beverly G.; Winkler, Anderson M.; Wittfeld, Katharina; Woldehawariat, Girma; Wolf, Christiane; Wolfers, Thomas; Yanek, Lisa R.; Yang, Jingyun; Zijdenbos, Alex; Zwiers, Marcel P.; Agartz, Ingrid; Almasy, Laura; Ames, David; Amouyel, Philippe; Andreassen, Ole Andreas; Arepalli, Sampath; Assareh, Amelia A.; Barral, Sandra; Bastin, Mark E.; Becker, Diane M.; Becker, James T.; Bennett, David A.; Blangero, John; Van Bokhoven, Hans; Boomsma, Dorret I.; Brodaty, Henry; Brouwer, Rachel M.; Brunner, Han G.; Buckner, Randy L.; Buitelaar, Jan K.; Bulayeva, Kazima B.; Cahn, Wiepke; Calhoun, Vince D.; Cannon, Dara M.; Cavalleri, Gianpiero L.; Cheng, Ching-Yu; Cichon, Sven; Cookson, Mark R.; Corvin, Aiden; Crespo-Facorro, Benedicto; Curran, Joanne E.; Czisch, Michael; Dale, Anders; Davies, Gareth E.; de Craen, Anton J.M.; de Geus, Eco J.C.; De Jager, Philip L.; de Zubicaray, Greig I.; Deary, Ian J.; Debette, Stéphanie; Decarli, Charles; Delanty, Norman; Depondt, Chantal; Destefano, Anita; Dillman, Allissa; Djurovic, Srdjan; Donohoe, Gary; Drevets, Wayne C.; Duggirala, Ravi; Dyer, Thomas D.; Enzinger, Christian; Erk, Susanne; Espeseth, Thomas; Fedko, Iryna O.; Fernandéz, Guillén; Ferrucci, Luigi; Fisher, Simon E.; Fleischman, Debra A.; Ford, Ian; Fornage, Myriam; Foroud, Tatiana M.; Fox, Peter T.; Francks, Clyde; Fukunaga, Masaki; Gibbs, J. Raphael; Glahn, David C.; Gollub, Randy L.; Göring, Harald H.H.; Green, Robert C.; Gruber, Oliver; Gudnason, Vilmundur; Guelfi, Sebastian; Håberg, Asta; Hansell, Narelle K.; Hardy, John; Hartman, Catharina A.; Hashimoto, Ryota; Hegenscheid, Katrin; Heinz, Andreas; Le Hellard, Stephanie; Hernandez, Dena G.; Heslenfeld, Dirk J.; Ho, Beng-Choon; Hoekstra, Pieter J.; Hoffmann, Wolfgang; Hofman, Albert; Holsboer, Florian; Homuth, Georg; Hosten, Norbert; Hottenga, Jouke-Jan; Huentelman, Matthew; Pol, Hilleke E. Hulshoff; Ikeda, Masashi; Jack, Clifford R.; Jenkinson, Mark; Johnson, Robert; Jönsson, Erik Gunnar; Jukema, J. 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Nature Neuroscience.  ISSN 1097-6256.  19(12), s 1569- 1582 . doi: 10.1038/nn.4398
• Andreou, Dimitrios; Söderman, Erik; Axelsson, Tomas; Sedvall, Göran C.; Terenius, Lars; Agartz, Ingrid & Jönsson, Erik G. (2016). Associations between a locus downstream DRD1 gene and cerebrospinal fluid dopamine metabolite concentrations in psychosis. Neuroscience Letters.  ISSN 0304-3940.  619, s 126- 130 . doi: 10.1016/j.neulet.2016.03.005
• Engen, Kristine & Agartz, Ingrid (2016). Anti-NMDA-reseptorencefalitt. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  136(11), s 1006- 1009
• Fagerberg, Tomas; Söderman, Erik; Gustavsson, Petter; Agartz, Ingrid & Jönsson, Erik Gunnar (2016). Personality traits in established schizophrenia: aspects of usability and differences between patients and controls using the Swedish universities Scales of Personality. Nordic Journal of Psychiatry.  ISSN 0803-9488.  70(6), s 462- 469 . doi: 10.3109/08039488.2016.1159331
• Guadalupe, Tulio; Mathias, Samuel R.; VanErp, Theo G.M.; Whelan, Christopher D.; Zwiers, Marcel P.; Abe, Yoshinari; Abramovic, Lucija; Agartz, Ingrid; Andreassen, Ole Andreas; Arias-Vásquez, Alejandro; Aribisala, Benjamin S.; Armstrong, Nicola J.; Arolt, Volker; Artiges, Eric; Ayesa-Arriola, Rosa; Baboyan, Vatche G.; Banaschewski, Tobias; Barker, Gareth; Bastin, Mark E.; Baune, Bernhard T.; Blangero, John; Bokde, Arun L.W.; Boedhoe, Premika S.W.; Bose, Anushree; Brem, Silvia; Brodaty, Henry; Bromberg, Uli; Brooks, Samantha; Büchel, Christian; Buitelaar, Jan; Calhoun, Vince D.; Cannon, Dara M.; Cattrell, Anna; Cheng, Yuqi; Conrod, Patricia J.; Conzelmann, Annette; Corvin, Aiden; Crespo-Facorro, Benedicto; Crivello, Fabrice; Dannlowski, Udo; de Zubicaray, Greig I.; de Zwarte, Sonja M.C.; Deary, Ian J.; Desrivieres, Sylvane; Doan, Nhat Trung; Donohoe, Gary; Dørum, Erlend Solberg; Ehrlich, Stefan; Espeseth, Thomas; Fernandéz, Guillén; Flor, Herta; Fouche, Jean-Paul; Frouin, Vincent; Fukunaga, Masaki; Gallinat, Jurgen; Garavan, Hugh; Gill, Michael; Suarez, Andrea Gonzalez; Gowland, Penny; Grabe, Hans J.; Grotegerd, Dominik; Gruber, Oliver; Hagenaars, Saskia; Hashimoto, Ryota; Hauser, Tobias U.; Heinz, Andreas; Hibar, Derrek; Hoekstra, Pieter J.; Hoogman, Martine; Howells, Fleur M.; Hu, Hao; Hulshoff Pol, Hilleke E.; Huyser, Chaim; Ittermann, Bernd; Jahanshad, Neda; Jönsson, Erik Gunnar; Jurk, Sarah; Kahn, René S.; Kelly, Sinead; Kraemer, Bernd; Kugel, Harald; Kwon, Jun Soo; Lemaitre, Herve; Lesch, Klaus-Peter; Lochner, Christine; Luciano, Michelle; Marquand, André F.; Martin, Nicholas G.; Martinez-Zalacain, Ignacio; Martinot, Jean-Luc; Mataix-Cols, David; Mather, Karen; McDonald, Colm; McMahon, Katie L.; Medland, Sarah E.; Menchon, José M.; Morris, Derek W.; Mothersill, Omar; Maniega, Susana Munoz; Mwangi, Benson; Nakamae, Takashi; Nakao, Tomohiro; Narayanaswaamy, Janardhanan C.; Nees, Frauke; Nordvik, Jan Egil; Onnink, A. Marten H.; Opel, Nils; Ophoff, Roel; Paillere Martinot, Marie-Laure; Papadopoulos Orfanos, Dimitri; Pauli, Paul; Paus, Tomáš; Poustka, Luise; Reddy, Janardhan Y.C.; Renteriá, Miguel E.; Roiz-Santiañez, Roberto; Roos, Annerine; Royle, Natalie A.; Sachdev, Perminder; Sánchez-Juan, Pascual; Schmaal, Lianne; Schumann, Gunter; Shumskaya, Elena; Smolka, Michael N.; Soares, Jair C.; Soriano-Mas, Carles; Stein, Dan J.; Strike, Lachlan T.; Toro, Roberto; Turner, Jessica A.; Tzourio-Mazoyer, Nathalie; Uhlmann, Anne; Hernández, Maria Valdés; van den Heuvel, Odile A.; van der Meer, Dennis; van Haren, Neeltje E.M.; Veltman, Dick J.; Venkatasubramanian, Ganesan; Vetter, Nora C.; Vuletic, Daniella; Walitza, Susanne; Walter, Henrik; Walton, Esther; Wang, Zhen; Wardlaw, Joanna; Wen, Wei; Westlye, Lars Tjelta; Whelan, Robert; Wittfeld, Katharina; Wolfers, Thomas; Wright, Margaret J.; Xu, Jian; Xu, Xiufeng; Yun, Je-Yeon; Zhao, JingJing; Franke, Barbara; Thompson, Paul M.; Glahn, David C.; Mazoyer, Bernard; Fisher, Simon E. & Francks, Clyde (2016). Human subcortical brain asymmetries in 15,847 people worldwide reveal effects of age and sex. Brain Imaging and Behavior.  ISSN 1931-7557.  Published ahead of print, s 1- 18 . doi: 10.1007/s11682-016-9629-z
• Haukvik, Unn Kristin H.; Hartberg, Cecilie Bhandari; Nerland, Stener; Jørgensen, Kjetil Nordbø; Lange, Elisabeth; Simonsen, Carmen Elisabeth; Nesvåg, Ragnar; Dale, Anders; Andreassen, Ole Andreas; Melle, Ingrid & Agartz, Ingrid (2016). No progressive brain changes during a 1-year follow-up of patients with first-episode psychosis. Psychological Medicine.  ISSN 0033-2917.  46(3), s 589- 598 . doi: 10.1017/S003329171500210X Show summary

  Background. First-episode psychosis (FEP) patients show structural brain abnormalities. Whether the changes are progressive or not remain under debate, and the results from longitudinal magnetic resonance imaging (MRI) studies are mixed. We investigated if FEP patients showed a different pattern of regional brain structural change over a 1-year period compared with healthy controls, and if putative changes correlated with clinical characteristics and outcome. Method. MRIs of 79 FEP patients [SCID-I-verified diagnoses: schizophrenia, psychotic bipolar disorder, or other psychoses, mean age 27.6 (S.D. = 7.7) years, 66% male] and 82 healthy controls [age 29.3 (S.D. = 7.2) years, 66% male] were acquired from the same 1.5 T scanner at baseline and 1-year follow-up as part of the Thematically Organized Psychosis (TOP) study, Oslo, Norway. Scans were automatically processed with the longitudinal stream in FreeSurfer that creates an unbiased within-subject template image. General linear models were used to analyse longitudinal change in a wide range of subcortical volumes and detailed thickness and surface area estimates across the entire cortex, and associations with clinical characteristics. Results. FEP patients and controls did not differ significantly in annual percentage change in cortical thickness or area in any cortical region, or in any of the subcortical structures after adjustment for multiple comparisons. Within the FEP group, duration of untreated psychosis, age at illness onset, antipsychotic medication use and remission at follow-up were not related to longitudinal brain change. Conclusions. We found no significant longitudinal brain changes over a 1-year period in FEP patients. Our results do not support early progressive brain changes in psychotic disorders.

• Hibar, Derrek; Westlye, Lars Tjelta; Van Erp, TGM; Rasmussen, J; Leonardo, CD; Faskowitz, J; Haukvik, Unn Kristin H.; Hartberg, Cecilie Bhandari; Doan, Nhat Trung; Agartz, Ingrid; Dale, AM; Gruber, O; Krämer, B; Trost, S; Liberg, B; Abe, C; Ekman, CJ; Ingvar, M; Landen, M; Fears, SC; Freimer, NB; Bearden, CE; Sprooten, E; Glahn, DC; Pearlson, GD; Emsell, L; Kenney, J; Scanlon, C; McDonald, C; Cannon, DM; Almeida, J; Versace, A; Caseras, X; Lawrence, NS; Phillips, ML; Dima, D; Delvecchio, G; Frangou, S; Satterthwaite, TD; Wolf, D; Houenou, J; Henry, C; Malt, Ulrik Fredrik; Bøen, Erlend; Elvsåshagen, Torbjørn; Young, AH; Lloyd, AJ; Goodwin, GM; Mackay, CE; Bourne, C; Bilderbeck, A; Abramovic, L; Boks, MP; Van Haren, NEM; Ophoff, RA; Kahn, RS; Bauer, M; Pfennig, A; Alda, M; Hajek, T; Mwangi, B; Soares, JC; Nickson, T; Dimitrova, R; Sussmann, JE; Hagenaars, S; Whalley, HC; McIntosh, AM; Thompson, PM & Andreassen, Ole Andreas (2016). Subcortical volumetric abnormalities in bipolar disorder. Molecular Psychiatry.  ISSN 1359-4184.  21(12), s 1710- 1716 . doi: 10.1038/mp.2015.227 Show summary

  Considerable uncertainty exists about the defining brain changes associated with bipolar disorder (BD). Understanding and quantifying the sources of uncertainty can help generate novel clinical hypotheses about etiology and assist in the development of biomarkers for indexing disease progression and prognosis. Here we were interested in quantifying case–control differences in intracranial volume (ICV) and each of eight subcortical brain measures: nucleus accumbens, amygdala, caudate, hippocampus, globus pallidus, putamen, thalamus, lateral ventricles. In a large study of 1710 BD patients and 2594 healthy controls, we found consistent volumetric reductions in BD patients for mean hippocampus (Cohen’s d=−0.232; P=3.50 × 10−7) and thalamus (d=−0.148; P=4.27 × 10−3) and enlarged lateral ventricles (d=−0.260; P=3.93 × 10−5) in patients. No significant effect of age at illness onset was detected. Stratifying patients based on clinical subtype (BD type I or type II) revealed that BDI patients had significantly larger lateral ventricles and smaller hippocampus and amygdala than controls. However, when comparing BDI and BDII patients directly, we did not detect any significant differences in brain volume. This likely represents similar etiology between BD subtype classifications. Exploratory analyses revealed significantly larger thalamic volumes in patients taking lithium compared with patients not taking lithium. We detected no significant differences between BDII patients and controls in the largest such comparison to date. Findings in this study should be interpreted with caution and with careful consideration of the limitations inherent to meta-analyzed neuroimaging comparisons.

• Jørgensen, Kjetil Nordbø; Nerland, Stener; Norbom, Linn Christin Bonaventure; Doan, Nhat Trung; Nesvåg, Ragnar; Mørch-Johnsen, Lynn; Haukvik, Unn Kristin H.; Melle, Ingrid; Andreassen, Ole Andreas; Westlye, Lars Tjelta & Agartz, Ingrid (2016). Increased MRI-based cortical grey/white-matter contrast in sensory and motor regions in schizophrenia and bipolar disorder. Psychological Medicine.  ISSN 0033-2917.  46(9), s 1971- 1985 . doi: 10.1017/S0033291716000593
• Kaiser, Stefanie; Lyne, John; Agartz, Ingrid; Clarke, Mary; Mørch-Johnsen, Lynn & Færden, Ann (2016). Individual negative symptoms and domains – Relevance for assessment, pathomechanisms and treatment. Schizophrenia Research.  ISSN 0920-9964.  186, s 39- 45 . doi: 10.1016/j.schres.2016.07.013
• Mørch, Ragni Helene; Dieset, Ingrid; Færden, Ann; Hope, Sigrun; Aas, Monica; Nerhus, Mari; Gardsjord, Erlend Strand; Joa, Inge; Morken, Gunnar; Agartz, Ingrid; Aukrust, Pål; Djurovic, Srdjan; Melle, Ingrid; Ueland, Thor & Andreassen, Ole Andreas (2016). Inflammatory evidence for the psychosis continuum model. Psychoneuroendocrinology.  ISSN 0306-4530.  67, s 189- 197 . doi: 10.1016/j.psyneuen.2016.02.011
• Mørch-Johnsen, Lynn; Nesvåg, Ragnar; Jørgensen, Kjetil Nordbø; Lange, Elisabeth; Hartberg, Cecilie Bhandari; Haukvik, Unn Kristin H.; Kompus, Kristiina; Westerhausen, Rene; Osnes, Kåre; Andreassen, Ole Andreas; Melle, Ingrid; Hugdahl, Kenneth & Agartz, Ingrid (2016). Auditory cortex characteristics in schizophrenia: Associations with auditory hallucinations. Schizophrenia Bulletin.  ISSN 0586-7614.  43(1), s 75- 83 . doi: 10.1093/schbul/sbw130
• Qian, Peng; Schork, Andrew J.; Bartsch, Hauke; Lo, Min-Tzu; Panizzon, Matthew S.; Westlye, Lars Tjelta; Kremen, William S.; Jernigan, Terry L.; Le Hellard, Stephanie; Steen, Vidar Martin; Espeseth, Thomas; Huentelman, Matt; Håberg, Asta; Agartz, Ingrid; Djurovic, Srdjan; Andreassen, Ole Andreas; Dale, Anders; Schork, Nicholas J.; Chen, Chi-Hua & Schork, Nicholas J (2016). Conservation of Distinct Genetically-Mediated Human Cortical Pattern. PLoS Genetics.  ISSN 1553-7390.  12:e1006143(7) . doi: 10.1371/journal.pgen.1006143 Full text in Research Archive.
• Ringen, Petter Andreas; Nesvåg, Ragnar; Helle, Siri; Lagerberg, Trine Vik; Lange, Elisabeth; Løberg, Else-Marie; Agartz, Ingrid; Andreassen, Ole Andreas & Melle, Ingrid (2016). Premorbid cannabis use is associated with more symptoms and poorer functioning in schizophrenia spectrum disorder. Psychological Medicine.  ISSN 0033-2917.  46(15), s 3127- 3136 . doi: 10.1017/S0033291716001999 Show summary

  Cannabis use disorder is associated with an earlier age at onset and a more severe outcome of schizophrenia spectrum disorders. The role of cannabis use before the onset of illness (premorbid cannabis use) has not been fully investigated. We here examined how amount and type of premorbid cannabis use was associated with the later course of illness including current substance use, symptoms and level of functioning in schizophrenia spectrum disorder. We used a naturalistic sample of patients with DSM-IV schizophrenia spectrum disorders with a comprehensive history of illness and substance use. Data on premorbid substance use was obtained from comprehensive self-report. The relationship to outcome was investigated using regression models that included current substance use and premorbid functioning. Pre-schizophrenia cannabis use was significantly associated with more severe psychotic symptoms and impaired functioning. Higher levels of premorbid cannabis use were associated with higher levels of current psychotic symptoms. These associations were independent of current substance use and premorbid functioning. Early use of cannabis (age <17 years) was associated with earlier age at onset of psychosis, independently of potential confounders. Pre-psychosis cannabis use affects illness outcome in schizophrenia spectrum disorders, and is associated with lower age at onset of psychosis. These findings of independent negative effects of premorbid cannabis use in schizophrenia suggest that a limitation of the general use of cannabis may have beneficial health effects.

• Skåtun, Kristina Cecilie; Kaufmann, Tobias; Doan, Nhat Trung; Alnæs, Dag; Còrdova Palomera, Aldo; Jönsson, Erik Gunnar; Fatouros-Bergman, Helena; Flyckt, Lena; Melle, Ingrid; Andreassen, Ole Andreas; Agartz, Ingrid & Westlye, Lars Tjelta (2016). Consistent functional connectivity alterations in schizophrenia spectrum disorder: a multisite study. Schizophrenia Bulletin.  ISSN 0586-7614.  43(4), s 914- 924 . doi: 10.1093/schbul/sbw145
• Skåtun, Kristina Cecilie; Kaufmann, Tobias; Tønnesen, Siren; Biele, Guido; Melle, Ingrid; Agartz, Ingrid; Alnæs, Dag; Andreassen, Ole Andreas & Westlye, Lars Tjelta (2016). Global brain connectivity alterations in persons with schizophrenia and bipolar spectrum disorders. Journal of Psychiatry & Neuroscience.  ISSN 1180-4882.  41(5), s 331- 341 . doi: 10.1503/jpn.150159 Full text in Research Archive.
• Steen, Nils Eiel; Aas, Monica; Simonsen, Carmen Elisabeth; Dieset, Ingrid; Tesli, Martin Steen; Nerhus, Mari; Gardsjord, Erlend Strand; Mørch, Ragni Helene; Agartz, Ingrid; Melle, Ingrid; Ueland, Torill; Spigset, Olav & Andreassen, Ole Andreas (2016). Serum levels of second-generation antipsychotics are associated with cognitive function in psychotic disorders. World Journal of Biological Psychiatry.  ISSN 1562-2975.  18(6), s 471- 482 . doi: 10.1080/15622975.2016.1245441
• Steen, Nils Eiel; Aas, Monica; Simonsen, Carmen Elisabeth; Dieset, Ingrid; Tesli, Martin Steen; Nerhus, Mari; Gardsjord, Erlend Strand; Mørch, Ragni Helene; Agartz, Ingrid; Melle, Ingrid; Vaskinn, Anja; Spigset, Olav & Andreassen, Ole Andreas (2016). Serum concentrations of mood stabilizers are associated with memory, but not other cognitive domains in psychosis spectrum disorders; explorative analyses in a naturalistic setting. International journal of bipolar disorders.  ISSN 2194-7511.  4(24) . doi: 10.1186/s40345-016-0067-z
• Tamnes, Christian Krog & Agartz, Ingrid (2016). White Matter Microstructure in Early-Onset Schizophrenia: A Systematic Review of Diffusion Tensor Imaging Studies. Journal of the American Academy of Child and Adolescent Psychiatry.  ISSN 0890-8567.  55(4), s 269- 279 . doi: 10.1016/j.jaac.2016.01.004
• Tesli, Martin Steen; Wirgenes, Katrine Verena; Hughes, Timothy; Bettella, Francesco; Athanasiu, Lavinia; Hoseth, Eva Zsuzsanna; Nerhus, Mari; Lagerberg, Trine Vik; Steen, Nils Eiel; Agartz, Ingrid; Melle, Ingrid; Dieset, Ingrid; Djurovic, Srdjan & Andreassen, Ole Andreas (2016). VRK2 gene expression in schizophrenia, bipolar disorder and healthy controls. British Journal of Psychiatry.  ISSN 0007-1250.  209(2), s 114- 120 . doi: 10.1192/bjp.bp.115.161950
• Andreou, Dimitrios; Söderman, Erik; Axelsson, Tomas; Sedvall, Göran C.; Terenius, Lars; Agartz, Ingrid & Jönsson, Erik Gunnar (2015). Cerebrospinal fluid monoamine metabolite concentrations as intermediate phenotypes between glutamate-related genes and psychosis. Psychiatry Research.  ISSN 0165-1781.  229(1-2), s 497- 504 . doi: 10.1016/j.psychres.2015.06.023
• Barrett, Elizabeth Ann; Mork, Erlend; Færden, Ann; Nesvåg, Ragnar; Agartz, Ingrid; Andreassen, Ole Andreas & Melle, Ingrid (2015). The development of insight and its relationship with suicidality over one year follow-up in patients with first episode psychosis. Schizophrenia Research.  ISSN 0920-9964.  162(1-3), s 97- 102 . doi: 10.1016/j.schres.2015.01.004
• Brandt, Christine Lycke; Doan, Nhat Trung; Tønnesen, Siren; Agartz, Ingrid; Hugdahl, Kenneth; Melle, Ingrid; Andreassen, Ole Andreas & Westlye, Lars Tjelta (2015). Assessing brain structural associations with working-memory related brain patterns in schizophrenia and healthy controls using linked independent component analysis. NeuroImage: Clinical.  ISSN 2213-1582.  9, s 253- 263 . doi: 10.1016/j.nicl.2015.08.010 Full text in Research Archive.
• Brandt, Christine Lycke; Kaufmann, Tobias; Agartz, Ingrid; Hugdahl, Kenneth; Jensen, Jimmy Kristian; Ueland, Toril; Haatveit, Beathe Christin; Skåtun, Kristina Cecilie; Doan, Nhat Trung; Melle, Ingrid; Andreassen, Ole Andreas & Westlye, Lars Tjelta (2015). Cognitive effort and schizophrenia modulate large-scale functional brain connectivity. Schizophrenia Bulletin.  ISSN 0586-7614.  41(6), s 1360- 1369 . doi: 10.1093/schbul/sbv013
• Bulik-Sullivan, Brendan; Loh, Po-Ru; Finucane, Hilary K.; Ripke, Stephan; Yang, Jian; Patterson, Nick; Daly, Mark J.; Price, Alkes L.; Neale, Benjamin M.; Agartz, Ingrid; Djurovic, Srdjan; Joa, Inge; Mattingsdal, Morten & Melle, Ingrid (2015). LD score regression distinguishes confounding from polygenicity in genome-wide association studies. Nature Genetics.  ISSN 1061-4036.  47(3), s 291- 295 . doi: 10.1038/ng.3211
• Chen, Chi-Hua; Peng, Qian; Schork, Andrew J.; Lo, Min-Tzu; Fan, Chun-Chieh; Wang, Yunpeng; Desikan, Rahul S.; Bettella, Franscesco; Hagler, Donald J.; Westlye, Lars Tjelta; Kremen, William S.; Jernigan, Terry L.; Le Hellard, Stephanie; Steen, Vidar Martin; Espeseth, Thomas; Huentelman, Matt; Håberg, Asta; Agartz, Ingrid; Djurovic, Srdjan; Andreassen, Ole Andreas; Schork, Nicholas & Dale, Anders (2015). Large-scale genomics unveil polygenic architecture of human cortical surface area. Nature Communications.  ISSN 2041-1723.  6:7549 . doi: 10.1038/ncomms8549 Full text in Research Archive.
• Dieset, Ingrid; Haukvik, Unn Kristin H.; Melle, Ingrid; Røssberg, Jan Ivar; Ueland, Thor; Hope, Sigrun; Dale, Anders M.; Djurovic, Srdjan; Aukrust, Pål; Agartz, Ingrid & Andreassen, Ole Andreas (2015). Association between altered brain morphology and elevated peripheral endothelial markers — Implications for psychotic disorders. Schizophrenia Research.  ISSN 0920-9964.  161(2-3), s 222- 228 . doi: 10.1016/j.schres.2014.11.006
• Gupta, Cota Navin; Calhoun, Vince D; Rachakonda, Srinivas; Chen, Jiayu; Patel, Veena; Liu, Jingyuan; Andreassen, Ole Andreas & Agartz, Ingrid (2015). Patterns of gray matter abnormalities in schizophrenia based on an international mega-analysis. Schizophrenia Bulletin.  ISSN 0586-7614.  41(5), s 1133- 1142 . doi: 10.1093/schbul/sbu177
• Hartberg, Cecilie Bhandari; Jørgensen, Kjetil Nordbø; Haukvik, Unn Kristin H.; Westlye, Lars Tjelta; Melle, Ingrid; Andreassen, Ole Andreas & Agartz, Ingrid (2015). Lithium treatment and hippocampal subfields and amygdala volumes in bipolar disorder. Bipolar Disorders.  ISSN 1398-5647.  17(5), s 496- 506 . doi: 10.1111/bdi.12295
• Haukvik, Unn Kristin H.; Westlye, Lars Tjelta; Mørch-Johnsen, Lynn; Jørgensen, Kjetil Nordbø; Lange, Elisabeth; Dale, Anders M.; Melle, Ingrid; Andreassen, Ole Andreas & Agartz, Ingrid (2015). In Vivo Hippocampal Subfield Volumes in Schizophrenia and Bipolar Disorder. Biological Psychiatry.  ISSN 0006-3223.  77(6), s 581- 588 . doi: 10.1016/j.biopsych.2014.06.020
• Hibar, Derrek; Stein, Jason L; Renteria, Miguel E; Arias-Vasquez, Alejandro; Desrivieres, Sylvane; Jahanshad, Neda; Toro, Roberto; Wittfeld, Katharina; Abramovic, Lucija; Andersson, Micael; Aribisala, Benjamin S; Armstrong, Nicola J; Bernard, Manon; Bohlken, Marc M; Boks, Marco P; Bralten, Janita; Brown, Andrew; Mallar Chakravarty, M; Chen, Qiang; Ching, Christopher R K; Cuellar-Partida, Gabriel; Den Braber, Anouk; Giddaluru, Sudheer; Goldman, Aaron L; Grimm, Oliver; Guadalupe, Tulio; Hass, Johanna; Woldehawariat, Girma; Holmes, Avram J; Hoogman, Martine; Janowitz, Deborah; Jia, Tianye; Kim, Sungeun; Klein, Marieke; Kraemer, Bernd; Lee, Phil H; Olde Loohuis, Loes M; Luciano, Michelle; MacAre, Christine; Mather, Karen A; Mattheisen, Manuel; Milaneschi, Yuri; Nho, Kwangsik; Papmeyer, Martina; Ramasamy, Adaikalavan; Risacher, Shannon L; Roiz-Santianez, Roberto; Rose, Emma J; Salami, Alireza; Sämann, Philipp G; Schmaal, Lianne; Schork, Andrew J; Shin, Jean; Strike, Lachlan T; Teumer, Alexander; Van Donkelaar, Marjolein M J; Van Eijk, Kristel R; Walters, Raymond K; Westlye, Lars Tjelta; Whelan, Christopher D; Winkler, Anderson M; Zwiers, Marcel P; Alhusaini, Saud; Athanasiu, Lavinia; Ehrlich, Stefan; Hakobjan, Marina M H; Hartberg, Cecilie Bhandari; Haukvik, Unn Kristin H.; Heister, Angelien J G A M; Hoehn, David; Kasperaviciute, Dalia; Liewald, David C M; Lopez, Lorna M; Makkinje, Remco R R; Matarin, Mar; Naber, Marlies A M; Reese McKay, D; Needham, Margaret; Nugent, Allison C; Putz, Benno; Royle, Natalie A; Shen, Li; Sprooten, Emma; Trabzuni, Daniah; Van Der Marel, Saskia S L; Van Hulzen, Kimm J E; Walton, Esther; Wolf, Christiane; Almasy, Laura; Ames, David; Arepalli, Sampath; Assareh, Amelia A; Bastin, Mark E; Brodaty, Henry; Bulayeva, Kazima B; Carless, Melanie A; Cichon, Sven; Corvin, Aiden; Curran, Joanne E; Czisch, Michael; De Zubicaray, Greig I; Dillman, Allissa; Duggirala, Ravi; Dyer, Thomas D; Erk, Susanne; Fedko, Iryna O; Ferrucci, Luigi; Foroud, Tatiana M; Fox, Peter T; Fukunaga, Masaki; Raphael Gibbs, J; Göring, Harald H H; Green, Robert C; Guelfi, Sebastian; Hansell, Narelle K; Hartman, Catharina A; Hegenscheid, Katrin; Heinz, Andreas; Hernandez, Dena G; Heslenfeld, Dirk J; Hoekstra, Pieter J; Holsboer, Florian; Homuth, Georg; Hottenga, Jouke-Jan; Ikeda, Masashi; Jack, Clifford R; Jenkinson, Mark; Johnson, Robert; Kanai, Ryota; Keil, Maria; Kent, Jack W; Kochunov, Peter; Kwok, John B; Lawrie, Stephen M; Liu, Xinmin; Longo, Dan L; McMahon, Katie L; Meisenzahl, Eva; Melle, Ingrid; Mohnke, Sebastian; Montgomery, Grant W; Mostert, Jeanette C; Muhleisen, Thomas W; Nalls, Michael A; Nichols, Thomas E; Nilsson, Lars G; Nöthen, Markus M; Ohi, Kazutaka; Olvera, Rene L; Perez-Iglesias, Rocio; Bruce Pike, G; Potkin, Steven G; Reinvang, Ivar; Reppermund, Simone; Rietschel, Marcella; Romanczuk-Seiferth, Nina; Rosen, Glenn D; Rujescu, Dan; Schnell, Knut; Schofield, Peter R; Smith, Colin; Steen, Vidar Martin; Sussmann, Jessika E; Thalamuthu, Anbupalam; Toga, Arthur W; Traynor, Bryan J; Troncoso, Juan; Turner, Jessica A; Valdes Hernandez, Maria C; Van 'T Ent, Dennis; Van Der Brug, Marcel; Van Der Wee, Nic J A; Van Tol, Marie-Jose; Veltman, Dick J; Wassink, Thomas H; Westman, Eric; Zielke, Ronald H; Zonderman, Alan B; Ashbrook, David G; Hager, Reinmar; Lu, Lu; McMahon, Francis J; Morris, Derek W; Williams, Robert W; Brunner, Han G; Buckner, Randy L; Buitelaar, Jan K; Cahn, Wiepke; Calhoun, Vince D; Cavalleri, Gianpiero L; Crespo-Facorro, Benedicto; Dale, Anders M; Davies, Gareth E; Delanty, Norman; Depondt, Chantal; Djurovic, Srdjan; Drevets, Wayne C; Espeseth, Thomas; Gollub, Randy L; Ho, Beng-Choon; Hoffmann, Wolfgang; Hosten, Norbert; Kahn, Rene S; Le Hellard, Stephanie; Meyer-Lindenberg, Andreas; Muller-Myhsok, Bertram; Nauck, Matthias; Nyberg, Lars; Pandolfo, Massimo; Penninx, Brenda W J H; Roffman, Joshua L; Sisodiya, Sanjay M; Smoller, Jordan W; Van Bokhoven, Hans; Van Haren, Neeltje E M; Völzke, Henry; Walter, Henrik; Weiner, Michael W; Wen, Wei; White, Tonya; Agartz, Ingrid; Andreassen, Ole Andreas; Blangero, John; Boomsma, Dorret I; Brouwer, Rachel M; Cannon, Dara M; Cookson, Mark R; De Geus, Eco J C; Deary, Ian J; Donohoe, Gary; Fernandez, Guillen; Fisher, Simon E; Francks, Clyde; Glahn, David C; Grabe, Hans J; Gruber, Oliver; Hardy, John; Hashimoto, Ryota; Hulshoff Pol, Hilleke E; Jönsson, Erik Gunnar; Kloszewska, Iwona; Lovestone, Simon; Mattay, Venkata S; Mecocci, Patrizia; McDonald, Colm; McIntosh, Andrew M; Ophoff, Roel A; Paus, Tomas; Pausova, Zdenka; Ryten, Mina; Sachdev, Perminder S; Saykin, Andrew J; Simmons, Andy; Singleton, Andrew; Soininen, Hilkka; Wardlaw, Joanna M; Weale, Michael E; Weinberger, Daniel R; Adams, Hieab H H; Launer, Lenore J; Seiler, Stephan; Schmidt, Reinhold; Chauhan, Ganesh; Satizabal, Claudia L; Becker, James T; Yanek, Lisa; Van Der Lee, Sven J; Ebling, Maritza; Fischl, Bruce; Longstreth, WT; Greve, Douglas; Schmidt, Helena; Nyquist, Paul; Vinke, Louis N; Van Duijn, Cornelia M; Xue, Luting; Mazoyer, Bernard; Bis, Joshua C; Gudnason, Vilmundur; Seshadri, Sudha; Ikram, M Arfan; Martin, Nicholas G; Wright, Margaret J; Schumann, Gunter; Franke, Barbara; Thompson, Paul M & Medland, Sarah E (2015). Common genetic variants influence human subcortical brain structures. Nature.  ISSN 0028-0836.  520(7546), s 224- 229 . doi: 10.1038/nature14101
• Hope, Sigrun; Hoseth, Eva Zsuzsanna; Dieset, Ingrid; Mørch, Ragni Helene; Aas, Monica; Aukrust, Pål; Djurovic, Srdjan; Melle, Ingrid; Ueland, Toril; Agartz, Ingrid; Ueland, Thor; Westlye, Lars Tjelta & Andreassen, Ole Andreas (2015). Inflammatory markers are associated with general cognitive abilities in schizophrenia and bipolar disorder patients and healthy controls. Schizophrenia Research.  ISSN 0920-9964.  165(2-3), s 188- 194 . doi: 10.1016/j.schres.2015.04.004
• Hoseth, Eva Zsuzsanna; Westlye, Lars Tjelta; Hope, Sigrun; Dieset, Ingrid; Aukrust, Pål; Melle, Ingrid; Haukvik, Unn Kristin H.; Agartz, Ingrid; Ueland, Toril; Ueland, Thor & Andreassen, Ole Andreas (2015). Association between cytokine levels, verbal memory and hippocampus volume in psychotic disorders and healthy controls. Acta Psychiatrica Scandinavica.  ISSN 0001-690X.  133(1), s 53- 62 . doi: 10.1111/acps.12467
• Johansson, Martin M.; Van Geystelen, Anneleen; Larmuseau, Maarten H.D.; Djurovic, Srdjan; Andreassen, Ole Andreas; Agartz, Ingrid & Jazin, Elena (2015). Microarray analysis of copy number variants on the human y chromosome reveals novel and frequent duplications overrepresented in specific haplogroups. PLoS ONE.  ISSN 1932-6203.  10:e01337223(8) . doi: 10.1371/journal.pone.0137223
• Juuhl-Langseth, Monica; Hartberg, Cecilie Bhandari; Holmen, Aina; Thormodsen, Rune; Groote, Inge Rasmus; Rimol, Lars Morten; Emblem, Kyrre Eeg; Agartz, Ingrid & Rund, Bjørn Rishovd (2015). Impaired verbal learning is associated with larger caudate volumes in early onset schizophrenia spectrum disorders. PLoS ONE.  ISSN 1932-6203.  10:e0130435(7) . doi: 10.1371/journal.pone.0130435 Full text in Research Archive.
• Jørgensen, Kjetil Nordbø; Nesvåg, Ragnar; Gunleiksrud, Sindre; Raballo, Andrea; Jönsson, Erik Gunnar & Agartz, Ingrid (2015). First- and second-generation antipsychotic drug treatment and subcortical brain morphology in schizophrenia. European Archives of Psychiatry and Clinical Neuroscience.  ISSN 0940-1334. . doi: 10.1007/s00406-015-0650-9
• Jørgensen, Kjetil Nordbø; Skjærvø, Ingeborg; Mørch-Johnsen, Lynn; Haukvik, Unn Kristin H.; Lange, Elisabeth; Melle, Ingrid; Andreassen, Ole Andreas & Agartz, Ingrid (2015). Cigarette smoking is associated with thinner cingulate and insular cortices in patients with severe mental illness. Journal of Psychiatry & Neuroscience.  ISSN 1180-4882.  40(4), s 241- 249 . doi: 10.1503/jpn.140163
• Kaufmann, Tobias; Skåtun, Kristina Cecilie; Alnæs, Dag; Doan, Nhat Trung; Duff, Eugene; Tønnesen, Siren; Roussos, Evangelos; Ueland, Toril; Aminoff, Sofie Ragnhild; Lagerberg, Trine Vik; Agartz, Ingrid; Melle, Ingrid; Smith, Stephen M.; Andreassen, Ole Andreas & Westlye, Lars Tjelta (2015). Disintegration of sensorimotor brain networks in schizophrenia. Schizophrenia Bulletin.  ISSN 0586-7614.  41(6), s 1326- 1335 . doi: 10.1093/schbul/sbv060
• Kauppi, Karolina; Westlye, Lars Tjelta; Tesli, Martin Steen; Bettella, Franscesco; Brandt, Christine Lycke; Mattingsdal, Morten; Ueland, Toril; Espeseth, Thomas; Agartz, Ingrid; Melle, Ingrid; Djurovic, Srdjan & Andreassen, Ole Andreas (2015). Polygenic risk for schizophrenia associated with working memory-related prefrontal brain activation in patients with schizophrenia and healthy controls. Schizophrenia Bulletin.  ISSN 0586-7614.  41(3), s 736- 743 . doi: 10.1093/schbul/sbu152 Show summary

  Schizophrenia is a highly heritable and polygenic disease, and identified common genetic variants have shown weak individual effects. Many studies have reported altered working memory (WM)-related brain activation in schizophrenia, preferentially in the frontal lobe. Such differences in brain activations could reflect inherited alterations possibly involved in the disease etiology, or rather secondary disease-related mechanisms. The use of polygenic risk scores (PGRS) based on a large number of risk polymorphisms with small effects is a valuable approach to examine the effect of cumulative genetic risk on brain functioning. This study examined the impact of cumulative genetic risk for schizophrenia on WM-related brain activations, assessed with functional magnetic resonance imaging. For each participant (63 schizophrenia patients and 118 healthy controls), we calculated a PGRS for schizophrenia based on 18 862 single-nucleotide polymorphism in a large multicenter genome-wide association study including 9146 schizophrenia patients and 12 111 controls, performed by the Psychiatric Genomics Consortium. As expected, the PGRS was significantly higher in patients compared with healthy controls. Further, the PGRS was related to differences in frontal lobe brain activation between high and low WM demand. Specifically, even in absence of main effects of diagnosis, increased PGRS was associated with decreased activation difference in the right middle-superior prefrontal cortex (BA 10/11) and the right inferior frontal gyrus (BA 45). This effect was seen in both cases and controls, and was not influenced by sex, age, or task performance. The findings support the notion of dysregulation of frontal lobe functioning as an inherited vulnerability factor in schizophrenia.

• Lee, S. Hong; Byrne, Enda M.; Hultman, Christina M.; Kähler, Anna Katarina; Vinkhuyzen, Anna A.E.; Ripke, Stephan; Andreassen, Ole Andreas; Frisell, Thomas; Gusev, Alexander; Hu, Xinli; Karlsson, Robert; Mantzioris, Vasilis X.; McGrath, John J.; Mehta, Divya; Stahl, Eli A.; Zhao, Qiongyi; Kendler, Kenneth S.; Sullivan, Patrick F.; Price, Alkes L.; O'Donovan, Michael; Okada, Yukinori; Mowry, Bryan J.; Raychaudhuri, Soumya; Wray, Naomi R.; Djurovic, Srdjan; Agartz, Ingrid; Mattingsdal, Morten; Melle, Ingrid; Byerley, William; Cahn, Wiepke; Cantor, Rita M; Cichon, Sven; Cormican, Paul; Curtis, David; Escott-Price, Valentina; Gejman, Pablo V.; Georgieva, Lyudmila; Giegling, Ina; Hansen, Thomas F; Ingason, Andrés; Kim, Yunjung; Konte, Bettina; Lee, Phil H; McIntosh, Andrew; McQuillin, Andrew; Morris, Derek; Nothen, Markus M; O'Dushlaine, Colm T.; Olincy, Ann & Olsen, Line (2015). New data and an old puzzle: The negative association between schizophrenia and rheumatoid arthritis. International Journal of Epidemiology.  ISSN 0300-5771.  44(5), s 1706- 1721 . doi: 10.1093/ije/dyv136
• Maier, Robert; Moser, Gerhard; Chen, Guo-Bo; Ripke, S; Absher, Devin; Agartz, Ingrid; Akil, Huda; Amin, Farooq; Andreassen, Ole Andreas; Anjorin, Adebayo; Anney, Richard; Arking, Dan E.; Asherson, Philip; Azevedo, Maria H.; Backlund, Lena; Badner, Judith A.; Bailey, Anthony J.; Banaschewski, Tobias; Barchas, Jack D.; Barnes, Michael P.; Barrett, Thomas B.; Bass, Nicholas; Battaglia, Agatino; Bauer, Michael; Bayes, Mònica; Bellivier, Frank; Bergen, Sarah E; Berrettini, Wade; Betancur, Catalina; Bettecken, Thomas; Biederman, Joseph; Binder, Elisabeth B.; Black, Donald W.; Blackwood, Douglas H.R.; Bloss, Cinnamon S.; Boehnke, Michael; Boomsma, Dorret I.; Breen, Gerome; Breuer, Rene; Bruggeman, Richard; Djurovic, Srdjan; Mattingsdal, Morten; Melle, Ingrid; Morken, Gunnar; Coryell, William; Potash, James B.; Scheftner, William; Shi, Jianxin; Weissman, Myrna; Hultman, Christina M.; Landen, Michael & Levinson, Douglas F. (2015). Joint analysis of psychiatric disorders increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder. American Journal of Human Genetics.  ISSN 0002-9297.  96(2), s 283- 294 . doi: 10.1016/j.ajhg.2014.12.006
• Mørch-Johnsen, Lynn; Nesvåg, Ragnar; Færden, Ann; Haukvik, Unn Kristin H.; Jørgensen, Kjetil Nordbø; Lange, Elisabeth; Andreassen, Ole Andreas; Melle, Ingrid & Agartz, Ingrid (2015). Brain structure abnormalities in first-episode psychosis patients with persistent apathy. Schizophrenia Research.  ISSN 0920-9964.  164(1-3), s 59- 64 . doi: 10.1016/j.schres.2015.03.001 Full text in Research Archive.
• O'Dushlaine, Colm T.; Rossin, Lizzy; Lee, Phil H; Duncan, Laramie; Parikshak, Neelroop N.; Newhouse, Stephen J; Ripke, Stephan; Neale, Benjamin M; Purcell, Shaun M; Posthuma, Danielle; Nurnberger, John I.; Hong Lee, S; Faraone, Stephen V.; Perlis, Roy H.; Mowry, Bryan J.; Thapar, Anita; Goddard, Michael E; Witte, John; Absher, Devin; Agartz, Ingrid; Akil, Huda; Amin, Farooq; Andreassen, Ole Andreas; Anjorin, Adebayo; Anney, Richard; Anttila, Verneri; Arking, Dan E.; Asherson, Philip; Azevedo, Maria H.; Backlund, Lena; Badner, Judith A.; Bailey, Anthony J.; Banaschewski, Tobias; Barchas, Jack D.; Barnes, Michael; Barrett, Thomas B.; Bass, Nicholas; Battaglia, Agatino; Bauer, Michael; Bayes, Mònica; Bellivier, Frank; Bergen, Sarah E; Berrettini, Wade; Betancur, Catalina; Bettecken, Thomas; Biederman, Joseph; Djurovic, Srdjan; Mattingsdal, Morten; Melle, Ingrid; Morken, Gunnar; Holmans, Peter A. & Breen, Gerome (2015). Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways. Nature Neuroscience.  ISSN 1097-6256. . doi: 10.1038/nn.3922
• Rahm, Christoffer; Liberg, Benny; Reckless, Greg; Ousdal, Olga Therese; Melle, Ingrid; Andreassen, Ole Andreas & Agartz, Ingrid (2015). Negative symptoms in schizophrenia show association with amygdala volumes and neural activation during affective processing. Acta Neuropsychiatrica.  ISSN 0924-2708.  27(4), s 213- 220 . doi: 10.1017/neu.2015.11
• Schalling, Martin; Engberg, Göran; Andreassen, Ole Andreas; Erhardt, Sophie; Cunningham, Janet; Agartz, Ingrid; Petrovic, Predrag; Cervenka, Simon & Fatouros-Bergman, Helena (2015). Nya rön om schizofreni kan ge ny diagnostik och behandling. Läkartidningen.  ISSN 0023-7205.  112(42)
• Steen, Nils Eiel; Aas, Monica; Simonsen, Carmen Elisabeth; Dieset, Ingrid; Tesli, Martin Steen; Nerhus, Mari; Gardsjord, Erlend Strand; Mørch, Ragni Helene; Agartz, Ingrid; Melle, Ingrid; Vaskinn, Anja; Spigset, Olav & Andreassen, Ole Andreas (2015). Serum level of venlafaxine is associated with better memory in psychotic disorders. Schizophrenia Research.  ISSN 0920-9964.  169(1-3), s 386- 392 . doi: 10.1016/j.schres.2015.10.021
• Tesli, Martin Steen; Kauppi, Karolina; Bettella, Franscesco; Brandt, Christine Lycke; Kaufmann, Tobias; Espeseth, Thomas; Mattingsdal, Morten; Agartz, Ingrid; Melle, Ingrid; Djurovic, Srdjan; Westlye, Lars Tjelta & Andreassen, Ole Andreas (2015). Altered brain activation during emotional face processing in relation to both diagnosis and polygenic risk of bipolar disorder. PLoS ONE.  ISSN 1932-6203.  10:e0134202(7) . doi: 10.1371/journal.pone.0134202 Full text in Research Archive.
• van Erp, Theo GM; Hibar, Derrek; Rasmussen, JM; Glahn, David C; Pearlson, Godfrey D; Andreassen, Ole Andreas; Agartz, Ingrid; Westlye, Lars Tjelta; Haukvik, Unn Kristin H.; Dale, Anders; Melle, Ingrid; Hartberg, Cecilie Bhandari; Gruber, Oliver; Kraemer, B; Zilles, David; Donohoe, Gary; Kelly, Sinead; McDonald, Colm; Morris, DW; Cannon, DM; Corvin, A; Machielsen, MW; Koenders, Laura; De Haan, L; Veltman, Dick J.; Satterthwaite, TD; Wolf, DH; Gur, RC; Gur, RE; Potkin, Steven G; Mathalon, DH; Mueller, BA; Preda, A; Macciardi, F; Ehrlich, Stefan; Walton, Esther; Hass, J; Calhoun, Vince D; Bockholt, HJ; Sponheim, SR; Shoemaker, JM; van Haren, Neeltje EM; Pol, HE; Ophoff, RA; Kahn, René S; Roiz-Santianez, Roberto; Crespo-Facorro, Benedicto; Wang, L; Alpert, KI; Jönsson, Erik Gunnar; Dimitrova, R; Bois, C; Whalley, HC; McIntosh, AM; Lawrie, SM; Hashimoto, R; Thompson, Paul M. & Turner, Jessica A. (2015). Subcortical brain volume abnormalities in 2028 individuals with schizophrenia and 2540 healthy controls via the ENIGMA consortium. Molecular Psychiatry.  ISSN 1359-4184.  21(4), s 547- 553 . doi: 10.1038/mp.2015.63 Show summary

  The profile of brain structural abnormalities in schizophrenia is still not fully understood, despite decades of research using brain scans. To validate a prospective meta-analysis approach to analyzing multicenter neuroimaging data, we analyzed brain MRI scans from 2028 schizophrenia patients and 2540 healthy controls, assessed with standardized methods at 15 centers worldwide. We identified subcortical brain volumes that differentiated patients from controls, and ranked them according to their effect sizes. Compared with healthy controls, patients with schizophrenia had smaller hippocampus (Cohen’s d = − 0.46), amygdala (d = − 0.31), thalamus (d = − 0.31), accumbens (d = − 0.25) and intracranial volumes (d = − 0.12), as well as larger pallidum (d = 0.21) and lateral ventricle volumes (d = 0.37). Putamen and pallidum volume augmentations were positively associated with duration of illness and hippocampal deficits scaled with the proportion of unmedicated patients. Worldwide cooperative analyses of brain imaging data support a profile of subcortical abnormalities in schizophrenia, which is consistent with that based on traditional meta-analytic approaches. This first ENIGMA Schizophrenia Working Group study validates that collaborative data analyses can readily be used across brain phenotypes and disorders and encourages analysis and data sharing efforts to further our understanding of severe mental illness.

• Vaskinn, Anja; Hartberg, Cecilie Bhandari; Sundet, Kjetil Søren; Westlye, Lars Tjelta; Andreassen, Ole Andreas; Melle, Ingrid & Agartz, Ingrid (2015). Brain structure characteristics in intellectually superior schizophrenia. Psychiatry Research : Neuroimaging.  ISSN 0925-4927.  232(1), s 123- 129 . doi: 10.1016/j.pscychresns.2015.02.005
• Vilhjalmsson, Bjarni J.; Yang, Jing; Finucane, Hilary; Gusev, Anatoly; Lindstrom, S; Ripke, S; Genovese, Giulio; Loh, Poh-Kooh; Bhatia, Gaurav; Do, Ron; Hayeck, Tristan; Won, Hong-Hee; Andreassen, Ole Andreas; Agartz, Ingrid; Melle, Ingrid; Djurovic, Srdjan; Mattingsdal, Morten; Kathiresan, Sekar; Pato, Michele T.; Pato, Carlos N.; Tamimi, Rulla; Stahl, Eli A.; Zaitlen, Noah; Pasaniuc, Bogdan; Belbin, Gillian; Kenny, Eimear; Schierup, Mikkel; de Jager, Philip; Patsopoulos, Nikolaos A.; McCarroll, Steven A.; Daly, Mark; Purcell, Shaun; Chasman, Daniel I; Neale, Benjamin M; Goddard, Michael; Visscher, Peter M.; Kraft, Peter; Patterson, Nick; Hunter, David J.; Adank, Muriel; Ahsan, Habibul; Aittomäki, Kristiina; Baglietto, Laura; Berndt, Sonja I.; Blomquist, Carl; Canzian, Federico; Chang-Claude, Jenny; Chanock, Stephen J.; Crisponi, Laura; Czene, Kamilla & Price, Alkes L. (2015). Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores. American Journal of Human Genetics.  ISSN 0002-9297. . doi: 10.1016/j.ajhg.2015.09.001
• Aas, Monica; Etain, B; Bellivier, F; Henry,, C.; Lagerberg, Trine Vik; Ringen, Petter Andreas; Agartz, Ingrid; Gard, S; Kahn, J.P; Leboyer, M.; Andreassen, Ole Andreas & Melle, Ingrid (2014). Additive effects of childhood abuse and cannabis abuse on clinical expressions of bipolar disorders. Psychological Medicine.  ISSN 0033-2917.  44(8), s 1653- 1662 . doi: 10.1017/S0033291713002316
• Aas, Monica; Haukvik, Unn Kristin H.; Djurovic, Srdjan; Tesli, Martin Steen; Athanasiu, Lavinia; Bjella, Thomas; Hansson, Lars Johan Axel; Cattaneo, Annamaria; Agartz, Ingrid; Andreassen, Ole Andreas & Melle, Ingrid (2014). Interplay between childhood trauma and BDNF val66met variants on blood BDNF mRNA levels and on hippocampus subfields volumes in schizophrenia spectrum and bipolar disorders. Journal of Psychiatric Research.  ISSN 0022-3956.  59, s 14- 21 . doi: 10.1016/j.jpsychires.2014.08.011
• Andreou, Dimitrios; Söderman, Erik; Axelsson, Tomas; Sedvall, Göran C.; Terenius, Lars; Agartz, Ingrid & Jönsson, Erik Gunnar (2014). Polymorphisms in genes implicated in dopamine, serotonin and noradrenalin metabolism suggest association with cerebrospinal fluid monoamine metabolite concentrations in psychosis. Behavioral and Brain Functions.  ISSN 1744-9081.  10(26) . doi: 10.1186/1744-9081-10-26
• Brandt, Christine Lycke; Eichele, Tom; Melle, Ingrid; Sundet, Kjetil Søren; SERVER, ANDRES; Agartz, Ingrid; Hugdahl, Kenneth; Jensen, Jimmy Kristian & Andreassen, Ole Andreas (2014). Working memory networks and activation patterns in schizophrenia and bipolar disorder: comparison with healthy controls. British Journal of Psychiatry.  ISSN 0007-1250.  204(4), s 290- 298 . doi: 10.1192/bjp.bp.113.129254
• Finseth, Per Ivar; Sønderby, Ida Elken; Djurovic, Srdjan; Agartz, Ingrid; Malt, Ulrik Fredrik; Melle, Ingrid; Morken, Gunnar; Andreassen, Ole Andreas; Vaaler, Arne Einar & Tesli, Martin Steen (2014). Association analysis between suicidal behaviour and candidate genes of bipolar disorder and schizophrenia. Journal of Affective Disorders.  ISSN 0165-0327.  163, s 110- 114 . doi: 10.1016/j.jad.2013.12.018 Full text in Research Archive.
• Haukvik, Unn Kristin H.; McNeil, Thomas; Lange, Elisabeth; Melle, Ingrid; Dale, AM; Andreassen, Ole Andreas & Agartz, Ingrid (2014). Pre- and perinatal hypoxia associated with hippocampus/amygdala volume in bipolar disorder. Psychological Medicine.  ISSN 0033-2917.  44(5), s 975- 985 . doi: 10.1017/S0033291713001529 Full text in Research Archive.
• Haukvik, Unn Kristin H.; Rimol, Lars Morten; Cooper Roddey, J; Hartberg, Cecilie Bhandari; Lange, Elisabeth; Vaskinn, Anja; Melle, Ingrid; Andreassen, Ole Andreas; Dale, Anders & Agartz, Ingrid (2014). Normal Birth Weight Variation Is Related to Cortical Morphology Across the Psychosis Spectrum. Schizophrenia Bulletin.  ISSN 0586-7614.  40(2), s 410- 419 . doi: 10.1093/schbul/sbt005

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• Gurholt, Tiril Pedersen; Nerhus, Mari; Osnes, Kåre; Berg, Akiah Ottesen; Andreassen, Ole A.; Melle, Ingrid & Agartz, Ingrid (2018). Hippocampus volume reduction in psychosis spectrum could be ameliorated by vitamin D. Schizophrenia Research.  ISSN 0920-9964. . doi: 10.1016/j.schres.2018.03.011
• Gurholt, Tiril Pedersen; Nerhus, Mari; Osnes, Kåre; Jørgensen, Kjetil Nordbø; Berg, Akiah Ottesen; Andreassen, Ole Andreas; Melle, Ingrid & Agartz, Ingrid (2017). Age-Related Effect of Vitamin D on Hippocampus Volume in Schizophrenia and Bipolar Disorder.
• Nerland, Stener; Antosz, Anna; Lonning, Vera Louise Hiorth; Jørgensen, Kjetil Nordbø; Mørch-Johnsen, Lynn Egeland; Andreassen, Ole Andreas & Agartz, Ingrid (2017). A Manual for Classifying Anatomical Variation of Heschl's Gyrus.
• Córdova-Palomera, Aldo; Bettella, Francesco; Wang, Yunpeng; Doan, Nhat Trung; Alnæs, Dag; Moberget, Torgeir; Kaufmann, Tobias; Sønderby, Ida Elken; Agartz, Ingrid; Andreassen, Ole Andreas & Westlye, Lars Tjelta (2016). POTENTIAL BRAIN MORPHOLOGY INSTABILITY FEATURES MEDIATING THE ASSOCIATION BETWEEN GENOME-WIDE HOMOZYGOSITY AND ALTERED NEUROCOGNITION.
• Nerland, Stener; Jørgensen, Kjetil Nordbø; Jahren, Bjørn; Melle, Ingrid; Andreassen, Ole Andreas & Agartz, Ingrid (2016). A Topological Characterisation of Cortical Folding in Schizophrenia and Bipolar Disorder.
• Jørgensen, Kjetil Nordbø; Nerland, Stener; Norbom, Linn Christin Bonaventure; Doan, Nhat Trung; Nesvåg, Ragnar; Haukvik, Unn Kristin H.; Melle, Ingrid; Andreassen, Ole Andreas; Westlye, Lars Tjelta & Agartz, Ingrid (2015). Increased cortical gray/white matter intensity contrast in schizophrenia and bipolar disorder compared to healthy controls.
• Vaskinn, Anja; Hartberg, Cecilie Bhandari; Sundet, Kjetil Søren; Westlye, Lars Tjelta; Andreassen, Ole Andreas; Melle, Ingrid & Agartz, Ingrid (2015). To the editors: Reply to Anna R. Docherty. Psychiatry Research.  ISSN 0165-1781. . doi: 10.1016/j.pscychresns.2015.07.022.
• Aas, Monica; Aminoff, Sofie Ragnhild; Lagerberg, Trine Vik; Etain, Bruno; Agartz, Ingrid; Andreassen, Ole Andreas & Melle, Ingrid (2014). Affective lability in patients with bipolar disorders is associated with high levels of childhood trauma. Psychiatry Research.  ISSN 0165-1781.  218, s 252- 255 . doi: 10.1016/j.psychres.2014.03.046

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