Jostein Skjalg Hagemo

• Rehn, Marius; Heyerdahl, Fridtjof; Osbakk, Svein Are; Andresen, Åke Erling Lappen & Hagemo, Jostein Skjalg (2023). Challenges and Risks in Out-of-Hospital Transport of Patients During the Coronavirus Disease 2019 Pandemic. Air Medical Journal. ISSN 1067-991X. 42(3), p. 191–195. doi: 10.1016/j.amj.2023.02.002. Full text in Research Archive
• Bredmose, Per P.; Hagemo, Jostein Skjalg; Østergaard, Doris & Sollid, Stephen (2021). Combining in-situ simulation and live HEMS mission facilitator observation: a flexible learning concept. BMC Medical Education. ISSN 1472-6920. 21(1), p. 1–10. doi: 10.1186/s12909-021-03015-w. Full text in Research Archive
• Mæhlen, Jens Otto; Mikalsen, Roger; Heimdal, Hans Julius; Rehn, Marius; Hagemo, Jostein Skjalg & Ottestad, William Arne (2021). Pre-hospital critical care management of severe hypoxemia in victims of Covid-19: a case series. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine. ISSN 1757-7241. 29, p. 1–5. doi: 10.1186/s13049-021-00831-3. Full text in Research Archive
• Bredmose, Per Poelhøi; Stave, Halvard; Eriksen, Morten; Osbakk, Svein Are; Farstad, Gunnar & Hagemo, Jostein Skjalg (2020). Live Tissue Training on Anesthetized Pigs for Air Ambulance Crews. Air Medical Journal. ISSN 1067-991X. 40(1), p. 60–64. doi: 10.1016/j.amj.2020.10.003. Show summary

  Objective: Patients with life- or limb-threatening severe injuries pose a challenge to prehospital services. Time-critical decision making and treatment are challenging because of occasional incomplete information, limited resources, adverse environments, and a range of basic and advanced technical skills available. To prepare for these infrequent critical situations, medical personnel from the helicopter emergency medical service at Oslo University Hospital developed a 1-day advanced trauma training course focusing on individual skills and teamwork during resuscitative procedures. Methods: Participants were trained under supervision in teams on an established live tissue model with anesthetized pigs. A questionnaire-based evaluation was conducted before and after training to measure the feasibility of covering the allocated learning objectives in the time allotted and participants’ perception of any change in their skills as a result of the course. Results: The self-reported skill level in all learning objectives improved significantly. Combining all learning objectives, the median self-reported skill level was significantly increased from 4 to 6 points (P < .001). Conclusion: Experienced prehospital physicians and other health staff reported an increased level of skill and competence in lifesaving and limb-saving procedures after completing a brief, intense 1-day course using living anesthetized pigs and cadaver models.

• Bredmose, Per Poelhøi; Hagemo, Jostein Skjalg; Røislien, Jo; Østergaard, Doris & Sollid, Stephen J. M. (2020). In situ simulation training in helicopter emergency medical services: feasible for on-call crews? Advances in Simulation. ISSN 2059-0628. 5. doi: 10.1186/s41077-020-00126-0. Full text in Research Archive
• Hagemo, Jostein Skjalg; Bredmose, Per Poelhøi; Stave, Halvard; Rehn, Marius & Buskop, Christian (2019). Response to: Best practice advice on pre-hospital emergency anaesthesia &amp; advanced airway management. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine. ISSN 1757-7241. 27(1). doi: 10.1186/s13049-019-0613-7.
• Høiseth, Lars Øivind & Hagemo, Jostein Skjalg (2017). Predicting fluid responsiveness in whom? A simulated example of patient spectrum influencing the receiver operating characteristics curve. Journal of clinical monitoring and computing. ISSN 1387-1307. 32(2), p. 215–219. doi: 10.1007/s10877-017-0019-x.
• Hagemo, Jostein Skjalg; Christiaans, Sarah C.; Stanworth, Simon J.; Brohi, Karim H.; Johansson, Pär I. & Goslings, J. Carel [Show all 8 contributors for this article] (2015). Detection of acute traumatic coagulopathy and massive transfusion requirements by means of rotational thromboelastometry: An international prospective validation study. Critical Care. ISSN 1364-8535. 19(97). doi: 10.1186/s13054-015-0823-y.
• Hagemo, Jostein Skjalg; Stanworth, Simon; Juffermans, Nicole P.; Brohi, Karim; Cohen, Mitchell Jay & Johansson, Pär I. [Show all 10 contributors for this article] (2014). Prevalence, predictors and outcome of hypofibrinogenaemia in trauma: A multicentre observational study. Critical Care. ISSN 1364-8535. 18(2). doi: 10.1186/cc13798.
• Hagemo, Jostein Skjalg; Jørgensen, Jørgen Joakim; Ostrowski, Sisse R.; Holtan, Anders; Gundersen, Yngvar & Johansson, Pär I. [Show all 7 contributors for this article] (2013). Changes in fibrinogen availability and utilization in an animal model of traumatic coagulopathy. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine. ISSN 1757-7241. 21. doi: 10.1186/1757-7241-21-56.
• Hagemo, Jostein Skjalg; Næss, Pål Aksel; Johansson, Pär I.; Windeløv, NA; Cohen, MJ & Røislien, Jo [Show all 10 contributors for this article] (2013). Evaluation of TEG (R) and RoTEM (R) inter-changeability in trauma patients. Injury. ISSN 0020-1383. 44(5), p. 600–605. doi: 10.1016/j.injury.2012.11.016.
• Hagemo, Jostein Skjalg (2013). Prehospital detection of traumatic coagulopathy. Transfusion. ISSN 0041-1132. 53, p. 48S–51S. doi: 10.1111/trf.12035.
• Thorsen, Kenneth; Ringdal, Kjetil G.; Strand, Kristian; Søreide, Eldar; Hagemo, Jostein Skjalg & Søreide, Kjetil (2011). Clinical and cellular effects of hypothermia, acidosis and coagulopathy in major injury. British Journal of Surgery. ISSN 0007-1323. 98(7), p. 894–907. doi: 10.1002/bjs.7497.
• Jensen, Anders Gadegaard; Callesen, Torben; Hagemo, Jostein Skjalg; Hreinsson, Kári; Lund, Vesa & Nordmark, Johanna (2010). Scandinavian clinical practice guidelines on general anaesthesia for emergency situations. Acta Anaesthesiologica Scandinavica. ISSN 0001-5172. 54(8), p. 922–950. doi: 10.1111/j.1399-6576.2010.02277.x.

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• Simensen, Randi; Fjose, Lars Olav; Rehn, Marius; Hagemo, Jostein Skjalg; Thorsen, Kjetil & Heyerdahl, Fridtjof (2023). Comparison of three regimens with inhalational methoxyflurane versus intranasal fentanyl versus intravenous morphine in pre-hospital acute pain management: study protocol for a randomized controlled trial (PreMeFen). Trials. ISSN 1745-6215. 24(1). doi: 10.1186/s13063-023-07590-9. Show summary

  Background Pre-hospital pain management has traditionally been performed with intravenous (IV) morphine, but oligoanalgesia remain a recognized problem. Pain reduction is essential for patient satisfaction and is regarded as a measure of successful treatment. We aim to establish whether non-invasive methods such as inhalation of methoxyflurane is non-inferior to intranasal fentanyl or non-inferior to the well-known IV morphine in the pre-hospital treatment of acute pain. Method/design The PreMeFen study is a phase three, three-armed, randomized, controlled, non-inferiority trial to compare three regimens of analgesics: inhalation of methoxyflurane and intranasal (IN) fentanyl versus IV morphine. It is an open-label trial with a 1:1:1 randomization to the three treatment groups. The primary endpoint is the change in pain numeric rating scale (NRS) (0–10) from baseline to 10 min after start of investigational medicinal product administration (IMP). The non-inferiority margin was set to 1.3, and a sample size of 270 patients per protocol (90 in each treatment arm) will detect this difference with 90% power. Discussion We chose a study design with comparison of analgesic regimens rather than fixed doses because of the substantial differences in drug characteristics and for the results to be relevant to inform policymakers in the pre-hospital setting. We recognize that easier administration of analgesics will lead to better pain management for many patients if the regimens are as good as the existing, and hence, we chose a non-inferiority design. The primary endpoint, the change in pain (NRS) after 10 min, is set to address the immediate need of pain reduction for patients with acute prehospital pain. On a later stage, more analgesic methods are often available. Summary PreMeFen is a non-inferiority randomized controlled trial comparing three analgesic regimens aiming to establish whether inhalation of methoxyflurane or intranasal fentanyl is as good as IV morphine for fast reduction of acute pain in the prehospital setting.

• Hagemo, Jostein Skjalg; Skulberg, Arne Kristian; Rehn, Marius; Valberg, Morten; Pesonen, Maiju & Heimdal, Hans Julius [Show all 7 contributors for this article] (2022). Inhaled nitric oxide as temporary respiratory stabilization in patients with COVID-19 related respiratory failure (INOCOV): Study protocol for a randomized controlled trial. PLOS ONE. ISSN 1932-6203. 17(5). doi: 10.1371/journal.pone.0268822. Full text in Research Archive
• Høiseth, Lars Øivind & Hagemo, Jostein Skjalg (2016). Comparing measurement methods using linear least squares regression. Journal of clinical monitoring and computing. ISSN 1387-1307. 32(2), p. 373–374. doi: 10.1007/s10877-016-9955-0.
• Hagemo, Jostein Skjalg; Gaarder, Christine; Næss, Pål Aksel; Viksmoen, Yvonne & Heier, Hans Erik (2010). COMPARING TEG (R) AND ROTEM (R) AS POINT-OF-CARE DEVICES IN TRAUMA PATIENTS. Vox Sanguinis. ISSN 0042-9007. 99, p. 437–437.
• Bredmose, Per Poelhøi; Sollid, Stephen J. M. & Hagemo, Jostein Skjalg (2022). National implementation of whole crew on-call in situ simulation in Norwegian HEMS; feasibility, challenges, and possibilities . UiS. ISSN 978-82-8439-124-3.

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