Karl-Fredrik Lindegaard

• Sundseth, Jarle Østberg; Sundseth, Antje; Jacobsen, Eva Astrid; Pripp, Are Hugo; Sorteberg, Wilhelm; Altmann, Marianne; Lindegaard, Karl-Fredrik; Berg-Johnsen, Jon & Thommessen, Bente (2017). Predictors of early in-hospital Death after decompressive craniectomy in swollen middle cerebral artery infarction. Acta Neurochirurgica.  ISSN 0001-6268.  159(2), s 301- 306 . doi: 10.1007/s00701-016-3049-0
• Paulsen, Anne Henriette; Due-Tønnessen, Bernt Johan; Lundar, Tryggve & Lindegaard, Karl-Fredrik (2016). Cerebrospinal fluid (CSF) shunting and ventriculocisternostomy (ETV) in 400 pediatric patients. Shifts in understanding, diagnostics, case-mix, and surgical management during half a century. Child's Nervous System.  ISSN 0256-7040.  s 1- 10 . doi: 10.1007/s00381-016-3281-1
• Paulsen, Anne Henriette; Lundar, Tryggve & Lindegaard, Karl-Fredrik (2015). Pediatric hydrocephalus: 40-year outcomes in 128 hydrocephalic patients treated with shunts during childhood. Assessment of surgical outcome, work participation, and health-related quality of life. Journal of Neurosurgery: Pediatrics.  ISSN 1933-0707.  16(6), s 633- 641 . doi: 10.3171/2015.5.PEDS14532 Show summary

  Object Treatment for hydrocephalus has not advanced appreciably since the advent of CSF shunts more than 50 years ago. The outcome for pediatric patients with hydrocephalus has been the object for several studies; however, much uncertainty remains regarding the very long term outcome for these patients. Shunting became the standard treatment for hydrocephalus in Norway during the 1960s, and the first cohorts from this era have now reached middle age. Therefore, the objective of this study was to review surgical outcome, mortality, social outcome, and health-related quality of life in middle-aged patients treated for hydrocephalus during childhood. Methods Data were collected in all patients, age 14 years or less, who required a CSF shunt during the years 1967– 1970. Descriptive statistics were assessed regarding patient characteristics, surgical features, social functioning, and work participation. The time and cause of death, if applicable, were also determined. Kaplan-Meier survival estimates were used to determine the overall survival of patients. Information regarding self-perceived health and functional status was assessed using the 36-Item Short Form Health Survey (SF-36) and the Barthel Index score. Results A total of 128 patients were included in the study, with no patient lost to follow-up. Of the 128 patients in the study, 61 (47.6%) patients died during the 42–45 years of observation. The patients who died belonged to the tumor group (22 patients) and the myelomeningocele group (13 patients). The mortality rate was lowered to 39% if the patients with tumors were excluded. The overall mortality rates at 1, 2, 10, 20, and 40 years from time of initial shunt insertion were 16%, 24%, 31%, 40%, and 48% respectively. The incidence of shunt-related mortality was 8%. The majority of children graduated from a normal school (67%) or from a school specializing in education for physically handicapped children (20%). Self-perceived health was significantly poorer in 6 out of 8 domains assessed by SF-36 as compared with the background population. Functional status among the survivors varied greatly during the follow-up period, but the majority of patients were self-dependent. A total of 56% of the patients were socially independent, and 42% of the patients were employed. Conclusions Approximately half of the patients are still alive. During the 42–45 year follow-up period, the mortality rate was 48%. Two deaths were due to acute shunt failure, and at least 8% of the deaths were shunt related (probable or late onset). The morbidity in middle-aged individuals treated for pediatric hydrocephalus is considerable. The late mortality rate was low, but not negligible. Twelve patients died during the last 2 decades, 1 of whom died because of acute shunt failure. Although the shunt revision rate was decreasing during the study period, many patients required shunt surgery during adulthood. Forty-one revisions in 21 patients were performed during the last decade. Thus, there is an obvious need for life-long follow-up in these patients. http://thejns.org/doi/abs/10.3171/2015.5.PEDS14532

• Sundseth, Jarle; Sundseth, Antje; Thommessen, Bente; Johnsen, Lars Gunnar; Altmann, Marianne; Sorteberg, Wilhelm; Lindegaard, Karl-Fredrik & Berg-Johnsen, Jon (2015). Long-term outcome and quality of life after craniectomy in speech-dominant swollen middle cerebral artery infarction. Neurocritical Care.  ISSN 1541-6933.  22(1), s 6- 14 . doi: 10.1007/s12028-014-0056-y
• Sundseth, Jarle; Sundseth, Antje; Berg-Johnsen, Jon; Sorteberg, Wilhelm & Lindegaard, Karl-Fredrik (2014). Cranioplasty with autologous cryopreserved bone after decompressive craniectomy. Complications and risk factors for developing surgical site infection. Acta Neurochirurgica.  ISSN 0001-6268.  156(4), s 805- 811 . doi: 10.1007/s00701-013-1992-6
• Stanisic, Milo; Hald, John K; Rasmussen, Inge-André; Pripp, Are Hugo; Ivanovic, Jugoslav; Kolstad, Frode; Sundseth, Jarle; Züchner, Mark & Lindegaard, Karl-Fredrik (2013). Volume and densities of chronic subdural haematoma obtained from CT imaging as predictors of postoperative recurrence: a prospective study of 107 operated patients. Acta Neurochirurgica.  ISSN 0001-6268.  155(2), s 323- 333 . doi: 10.1007/s00701-012-1565-0
• Stanisic, Milo; Aasen, Ansgar Oddne; Pripp, Are Hugo; Lindegaard, Karl-Fredrik; Ramm-Pettersen, Jon-Terje; Lyngstadaas, Ståle Petter; Ivanovic, Jugoslav; Konglund, Ane; Ilstad, Eivind; Sandell, Tiril; Ellingsen, Omar & Sæhle, Terje (2012). Local and systemic pro-inflammatory and anti-inflammatory cytokine patterns in patients with chronic subdural hematoma: a prospective study. Inflammation Research.  ISSN 1023-3830.  61(8), s 845- 852 . doi: 10.1007/s00011-012-0476-0
• Stanisic, Milo; Lyngstadaas, Ståle Petter; Pripp, Are Hugo; Aasen, Ansgar Oddne; Lindegaard, Karl-Fredrik; Ivanovic, Jugoslav; Ilstad, Eivind; Konglund, Ane; Sandell, Tiril; Ellingsen, Theodor Omar Chammas & Sæhle, Terje (2012). Chemokines as markers of local inflammation and angiogenesis in patients with chronic subdural hematoma: a prospective study. Acta Neurochirurgica.  ISSN 0001-6268.  154(1), s 113- 120 . doi: 10.1007/s00701-011-1203-2
• Haug, Tonje Kristin; Sorteberg, Angelika Gabriel; Finset, Arnstein; Lindegaard, Karl-Fredrik; Lundar, Tryggve & Sorteberg, Wilhelm (2010). Cognitive Functioning and Health-Related Quality of Life 1 Year After Aneurysmal Subarachnoid Hemorrhage in Preoperative Comatose Patients (Hunt and Hess Grade V Patients). Neurosurgery.  ISSN 0148-396X.  66(3), s 475- 484 . doi: 10.1227/01.NEU.0000365364.87303.AC
• Paulsen, Anne Henriette; Lundar, Tryggve & Lindegaard, Karl-Fredrik (2010). Twenty-year outcome in young adults with childhood hydrocephalus:assessment of surgical outcome, work participation, and health-related quality of life.. Journal of Neurosurgery: Pediatrics.  ISSN 1933-0707.  Dec(6 (6)), s 527- 535 . doi: 10.3171/2010.9.PEDS09548
• Haug, Tonje Kristin; Sorteberg, Angelica; Sorteberg, Wilhelm; Lindegaard, Karl-Fredrik; Lundar, Tryggve & Finset, Arnstein (2009). SURGICAL REPAIR OF UNRUPTURED AND RUPTURED MIDDLE CEREBRAL ARTERY ANEURYSMS: IMPACT ON COGNITIVE FUNCTIONING AND HEALTH-RELATED QUALITY OF LIFE. Neurosurgery.  ISSN 0148-396X.  64(3), s 412- 420 . doi: 10.1227/01.NEU.0000338952.13880.4E
• Haug, Tonje Kristin; Sorteberg, Angelika; Sorteberg, Willhelm; Lindegaard, Karl-Fredrik; Lundar, Tryggve & Finset, Arnstein (2009). Cognitive functioning and health related quality of life after rupture of an aneurysm on the anterior communicating artery versus middle cerebral artery. British Journal of Neurosurgery.  ISSN 0268-8697.  23(5), s 507- 515 . doi: 10.1080/02688690902785701
• Haug, Tonje; Sorteberg, Angelika; Sorteberg, Wilhelm; Lindegaard, Karl-Fredrik; Lundar, Tryggve & Finset, Arnstein (2009). Surgical repair of unruptured and ruptured middle cerebral artery aneurysms: impact on cognitive functioning and health-related quality of life. Neurosurgery.  ISSN 0148-396X.  64(3), s 412- 420
• Lindegaard, Karl-Fredrik; Folkestad, Oddry H; Moen, Johanne & Sundseth, Jarle (2008). Hemikraniektomi ved akutt hjerneinfarkt. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  128(3), s 303- 307
• Haug, T; Sorteberg, A; Sorteberg, W; Lindegaard, Karl-Fredrik; Lundar, Tryggve & Finset, Arnstein (2007). Cognitive outcome after aneurysmal subarachnoid hemorrhage: Time course of recovery and relationship to clinical, radiological, and management parameters. Neurosurgery.  ISSN 0148-396X.  60 . doi: 10.1227/NEU.0000255414.70807.A0
• Haug, Tonje; Sorteberg, Angelika; Sorteberg, Wilhelm; Lindegaard, Karl-Fredrik; Lundar, Tryggve & Finset, Arnstein (2007). Cognitive outcome after aneurysmal subarachnoid hemorrhage: time course of recovery and relationship to clinical, radiological, and management parameters. Neurosurgery.  ISSN 0148-396X.  60(4), s 649- 657
• Wik, Kirsten E.; Lindegaard, Karl-Fredrik; Brunborg, Birgit; Bjørk, Ida Torunn & Rudland, Cornelia (2005). Livet etter akutt hjernehinneblødning. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  125(Årg. 125, nr 2), s 152- 154
• Wik, Kirsten E.; Lindegaard, Karl-Fredrik; Brunborg, Birgit; Bjørk, Ida Torunn & Ruland, Cornelia (2005). Livet etter akutt hjernehinneblødning. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  125(2), s 152- 154
• Lindegaard, Karl-Fredrik; Bakke, Søren Jacob; Pedersen, Hans Kristian & Lundar, Tryggve (2003). Impact of Guglielmi detachable coils on economic outcome of treating intracranial aneurysms - New technology does not mean higher costs. Rivista di neuroradiologia.  ISSN 1120-9976.  16, s 1195- 1200
• Boysen, Morten Ebbe; Due-Tønnessen, Bernt; Helseth, Eirik; Langmoen, Ivar A.; Lindegaard, Karl-Fredrik; Sorteberg, Willhelm; Bakke, Søren Jacob & Aaløkken, Trond Mogens (2001). Reseksjon av maligne svulster med relasjon til fremre skallegrop. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  14(121), s 1688- 1691
• Pedersen, Hans Kristian; Bakke, Søren Jacob; Hald, John Kløve; Skalpe, Ingar O; Anke, I.M.; Sagsveen, R.; Langmoen, Ivar A.; Lindegaard, Karl-Fredrik & Nakstad, Per Hjalmar (2001). CTA in patients with acute subarachnoid haemorrhage. A comparative study with selective, digital angiography and blinded, independent review. Acta Radiologica.  ISSN 0284-1851.  42, s 43- 50
• Sorteberg, Wilhelm; Sorteberg, Angelika; Lindegaard, Karl-Fredrik; Boysen, Morten Ebbe & Nornes, Helge (1999). Transcranial Doppler ultrasonography-guided management of internal carotid artery closure. Neurosurgery.  ISSN 0148-396X.  45(1), s 76- 88
• Sorteberg, Willhelm; Sorteberg, Angelica; Lindegaard, Karl-Fredrik; Boysen, Morten Ebbe & Nornes, Helge (1999). Transcranial Doppler Ultrasonography-guided Management of Internal Carotid Artery Closure. Neurosurgery.  ISSN 0148-396X.  45(1), s 76- 88
• Taubøll, Erik; Sorteberg, Wilhelm; Owe, Jone Furulund; Lindegaard, Karl-Fredrik; Rusten, Knut; Sorteberg, Angelika & Gjerstad, Leif (1999). Cerebral artery blood velocity in normal subjects during acute decreases in barometric pressure. Aviation, Space and Environmental Medicine.  ISSN 0095-6562.  70(7), s 692- 697
• Taubøll, Erik; Sorteberg, Willhelm; Owe, Jan Ove; Lindegaard, Karl-Fredrik; Rusten, Knut; Sorteberg, Angelica & Gjerstad, Leif (1999). Cerebral Artery Blood Velocity in Normal Subjects During Acute Decreases in Barometric Pressure. Aviation, Space and Environmental Medicine.  ISSN 0095-6562.  70(7), s 692- 697
• Sorteberg, Angelica; Sorteberg, Willhelm; Bakke, Søren Jacob; Lindegaard, Karl-Fredrik; Boysen, Morten Ebbe & Nornes, Helge (1998). Varying impact of common carotid artery digital compression and internal carotid artery balloon test occlusion on cerebral hemodynamics. Head and Neck.  ISSN 1043-3074.  20, s 687- 694
• Sorteberg, Angelika; Sorteberg, Wilhelm; Bakke, Søren Jacob; Lindegaard, Karl-Fredrik; Boysen, Morten Ebbe & Nornes, Helge (1998). Varying impact of common carotid artery digital compression and internal carotid artery balloon test occlusion on cerebral hemodynamics. Head and Neck.  ISSN 1043-3074.  20(8), s 687- 694
• Sorteberg, Angelica; Sorteberg, Willhelm; Bakke, Søren Jacob; Lindegaard, Karl-Fredrik; Boysen, Morten Ebbe & Nornes, Helge (1997). Cerebral haemodynamics in internal carotid artery trial occlusion. Acta Neurochirurgica.  ISSN 0001-6268.  139, s 1066- 1073
• Sorteberg, Angelika; Sorteberg, Wilhelm; Bakke, Søren Jacob; Lindegaard, Karl-Fredrik; Boysen, Morten Ebbe & Nornes, Helge (1997). Cerebral haemodynamics in internal carotid artery trial occlusion. Acta Neurochirurgica.  ISSN 0001-6268.  139(11), s 1066- 1073
• Sorteberg, Willhelm; Lindegaard, Karl-Fredrik; Taubøll, Erik; Owe, Jan Ove; Rusten, Knut & Gjerstad, Leif (1997). Cerebral artery velocity in normal subjects during acute changes in arterial blood oxygen content. Journal d'échographie et de médecine par ultrasons.  ISSN 0245-5552.  6
• Sorteberg, Angelica; Sorteberg, Willhelm; Lindegaard, Karl-Fredrik; Bakke, Søren Jacob & Nornes, Helge (1996). Haemodynamic classification of symptomatic obstructive carotid artery disease. Acta Neurochirurgica.  ISSN 0001-6268.  138
• Sorteberg, Angelica; Sorteberg, Willhelm; Lindegaard, Karl-Fredrik; Bakke, Søren Jacob & Nornes, Helge (1996). Haemodynamic classification of symptomatic obstructive carotid artery disease. Acta Neurochirurgica.  ISSN 0001-6268.  138, s 1079- 1087
• Sorteberg, Angelica; Sorteberg, Willhelm; Lindegaard, Karl-Fredrik; Bakke, J. S. & Nornes, Helge (1996). Haemodynamic classification of symptomatic obstructive carotid artery disease. Acta Neurochirurgica.  ISSN 0001-6268.  138, s 1079- 1087
• Sorteberg, Angelica; Sorteberg, Willhelm; Lindegaard, Karl-Fredrik & Nornes, Helge (1996). Cerebral haemodynamic considerations in obstructive carotid artery disease. Acta Neurochirurgica.  ISSN 0001-6268.  138, s 68- 76
• Sorteberg, Angelika; Sorteberg, Wilhelm; Lindegaard, Karl-Fredrik; Bakke, Søren Jacob & Nornes, Helge (1996). Haemodynamic classification of symptomatic obstructive carotid artery disease. Acta Neurochirurgica.  ISSN 0001-6268.  138(9), s 1079- 1087
• Sorteberg, Angelika; Sorteberg, Wilhelm; Lindegaard, Karl-Fredrik & Nornes, Helge (1996). Cerebral haemodynamic considerations in obstructive carotid artery disease. Acta Neurochirurgica.  ISSN 0001-6268.  138(1), s 68- 76
• Lundar, Tryggve; Lindegaard, Karl-Fredrik & Nornes, Helge (1990). Continuous recording of middle cerebral artery blood velocity in clinical neurosurgery. Acta Neurochirurgica.  ISSN 0001-6268.  102(3-4), s 85- 90
• Lundar, Tryggve; Lindberg, Harald L; Lindegaard, Karl-Fredrik; Tjønneland, Steinar; Rian, Renate; Bø, Gunnar & Nornes, Helge (1987). Cerebral perfusion during major cardiac surgery in children. Pediatric Cardiology.  ISSN 0172-0643.  8(3), s 161- 165
• Lundar, Tryggve; Lindegaard, Karl-Fredrik; Refsum, Liv; Rian, Renate; Bø, Gunnar & Nornes, Helge (1987). Cerebrovascular effects of isoflurane in man. Intracranial pressure and middle cerebral artery flow velocity. British Journal of Anaesthesia.  ISSN 0007-0912.  Oct 59(10), s 1208- 1213
• Lundar, Tryggve; Lindegaard, Karl-Fredrik; Frøysaker, Tor; Grip, Arne; Bergman, M; Åm-Holen, Einfrid & Nornes, Helge (1986). Cerebral carbon dioxide reactivity during nonpulsatile cardiopulmonary bypass. Annals of Thoracic Surgery.  ISSN 0003-4975.  May 41(5), s 525- 530
• Lundar, Tryggve; Frøysaker, Tor; Lindegaard, Karl-Fredrik; Wiberg, Jan; Lindberg, Harald L; Rostad, Hans & Nornes, Helge (1985). Some observations on cerebral perfusion during cardiopulmonary bypass. Annals of Thoracic Surgery.  ISSN 0003-4975.  Apr 39(4), s 318- 323
• Lundar, Tryggve; Lindegaard, Karl-Fredrik; Frøysaker, Tor; Aaslid, Rune; Grip, Arne & Nornes, Helge (1985). Dissociation between cerebral autoregulation and carbon dioxide reactivity during nonpulsative cardiopulmonary bypass. Annals of Thoracic Surgery.  ISSN 0003-4975.  Dec 40(6), s 582- 586
• Lundar, Tryggve; Lindegaard, Karl-Fredrik; Frøysaker, Tor; Aaslid, Rune; Wiberg, Jan & Nornes, Helge (1985). Cerebral perfusion during nonpulsatile cardiopulmonary bypass. Annals of Thoracic Surgery.  ISSN 0003-4975.  Aug 40(2), s 144- 150
• Lundar, Tryggve; Ganes, Trond & Lindegaard, Karl-Fredrik (1983). Induced barbiturate coma: methods for evaluation of patients. Critical Care Medicine.  ISSN 0090-3493.  Jul 11(7), s 559- 562

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• Lindegaard, Karl-Fredrik; Lundar, Tryggve; Hauglie-Hanssen, E.; Sorteberg, Angelika; Sorteberg, Wilhelm; Magnæs, B; Wiberg, Jan & Bakke, Søren Jacob (2019). OBITUARY HELGE NORNES, has works published, Professor. Tidsskrift for Den norske legeforening.  ISSN 0029-2001. . doi: 10.4045/tidsskr.19.0200
• Paulsen, Anne Henriette; Due-Tønnessen, Bernt Johan; Lundar, Tryggve & Lindegaard, Karl-Fredrik (2017). Persistent shunt dependency and very late shunt failure in a 3-year-old boy with idiopathic intracranial hypertension (IIH). Child's Nervous System.  ISSN 0256-7040.  33(2), s 213- 215 . doi: 10.1007/s00381-016-3316-7
• Sorteberg, Angelika; Nordermark, Tonje Haug; Finset, Arnstein; Lindegaard, Karl-Fredrik; Lundar, Tryggve & Sorteberg, Wilhelm (2013). Over-aggressive treatment of grade V SAH patients. Neurosurgery.  ISSN 0148-396X.  73(3), s 560- 561
• Paulsen, A. Henriette; Lundar, Tryggve & Lindegaard, Karl-Fredrik (2010). Shunt survival Response. Journal of Neurosurgery: Pediatrics.  ISSN 1933-0707.  6(6), s 526- 526
• Bakke, Søren Jacob; Lindegaard, Karl-Fredrik; Pedersen, Hans Kristian; Sorteberg, Willhelm; Nome, Terje; Tennøe, Bjørn & Due-Tønnessen, Paulina (2003). Outcome in individuals aged 70 years and more with ruptured intracranial aneurysm.
• Bakke, Søren Jacob; Pedersen, Hans Kristian; Nome, Terje; Sorteberg, Willhelm & Lindegaard, Karl-Fredrik (2003). Outcome in individuals aged 70 years and more with ruptured intracranial aneurysms.
• Bakke, Søren Jacob; Sorteberg, Willhelm; Lindegaard, Karl-Fredrik & Pedersen, Hans Kristian (2003). Outcome with ruptured intracranial aneurysm in individuals aged 70 years and more.
• Sorteberg, Willhelm; Bakke, Søren Jacob; Lundar, Tryggve & Lindegaard, Karl-Fredrik (2003). 636 individer med akutt intrakranial aneurysmeblødning (SAH), Rikshospitalet 1998-2002.
• Sorteberg, Willhelm; Bakke, Søren Jacob; Lundar, Tryggve & Lindegaard, Karl-Fredrik (2003). Negativt funn ved primær angiografi etter subaraknoidalblødning. Rikshospitalet 1998-2002.
• Lindegaard, Karl-Fredrik; Bakke, Søren Jacob & Pedersen, Hans Kristian (2002). Impact of Guglielmi detachable coils on economical and functional outcomes in patients with intracranial aneurysms.
• Lindegaard, Karl-Fredrik; Sorteberg, Willhelm; Bakke, Søren Jacob; Due-Tønnessen, Paulina & Lundar, Tryggve (2002). Ruptured intracranial aneurysm in the eight decade of life: A six-years`hospital cohort retrospective.
• Lindegaard, Karl-Fredrik; Pedersen, Hans Kristian; Bakke, Søren Jacob & Loge, Jon Håvard (2001). Intracranial aneurysms: Does "new technology" mean "higher costs"?.
• Sorteberg, Angelica; Sorteberg, Willhelm; Lindegaard, Karl-Fredrik & Nornes, Helge (1996). Cerebral haemodynamic considerations in obstructive carotid artery disease.
• Sorteberg, Angelica; Sorteberg, Willhelm; Lindegaard, Karl-Fredrik & Nornes, Helge (1996). Estimation of cerebral vasomotor reactivity in patients with obstructive carotid artery disease.

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