Knut Håkon Hole

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Visiting address Sognsvannsveien 20 None 0372 OSLO
Postal address Postboks 4950 Nydalen 0424 OSLO

Publications

  • Ryg, Una; Lilleby, Wolfgang; Hole, Knut Håkon; Lund-Iversen, Marius & Switlyk, Marta Daniela (2020). Local Recurrence of Prostate Cancer to the Intersphincteric Space: A Case Report. Urology.  ISSN 0090-4295. . doi: 10.1016/j.urology.2020.03.009
  • Abrahamsson, Hanna Josefine; Porojnicu, Alina Carmen; Lindstrøm, Jonas Christoffer; Dueland, Svein; Flatmark, Kjersti; Hole, Knut Håkon; Seierstad, Therese; Moan, Johan Emilian; Redalen, Kathrine; Meltzer, Sebastian & Ree, Anne Hansen (2019). High level of circulating vitamin D during neoadjuvant therapy may lower risk of metastatic progression in high-risk rectal cancer. BMC Cancer.  ISSN 1471-2407.  19(1) . doi: 10.1186/s12885-019-5724-z Full text in Research Archive.
  • Bains, Simer Jit; Abrahamsson, Hanna Josefine; Flatmark, Kjersti; Dueland, Svein; Hole, Knut Håkon; Seierstad, Therese; Redalen, Kathrine; Meltzer, Sebastian & Ree, Anne Hansen (2019). Immunogenic cell death by neoadjuvant oxaliplatin and radiation protects against metastatic failure in high-risk rectal cancer.. Cancer Immunology and Immunotherapy.  ISSN 0340-7004. . doi: 10.1007/s00262-019-02458-x Full text in Research Archive.
  • Meltzer, Sebastian; Bakke, Kine Mari; Rød, Karina Lund; Negård, Anne; Flatmark, Kjersti; Solbakken, Arne Mide; Kristensen, Annette Torgunrud; Fuglestad, Anniken Jørlo; Kersten, Christian; Dueland, Svein; Seierstad, Therese; Hole, Knut Håkon; Lyckander, Lars Gustav; Larsen, Finn Ole; Schou, Jakob Vasehus; Brown, Dawn; Abrahamsson, Hanna Josefine; Redalen, Kathrine & Ree, Anne Hansen (2019). Sex-related differences in primary metastatic site in rectal cancer; associated with hemodynamic factors?. Clinical and Translational Radiation Oncology.  ISSN 2405-6308.  21, s 5- 10 . doi: 10.1016/j.ctro.2019.11.006 Full text in Research Archive.
  • Hayman, Jonathan; Hole, Knut Håkon; Seierstad, Therese; Perin, Jamie; DeWeese, Theodore L; Tran, Phuoc T. & Lilleby, Wolfgang (2018). Local failure is a dominant mode of recurrence in locally advanced and clinical node positive prostate cancer patients treated with combined pelvic IMRT and androgen deprivation therapy. Urologic Oncology.  ISSN 1078-1439.  10, s 1- 14 . doi: 10.1016/j.urolonc.2018.09.016
  • Hompland, Tord; Hole, Knut Håkon; Ragnum, Harald Bull; Aarnes, Eva-Katrine; Vlatkovic, Ljiljana; Lie, Agnes Kathrine; Patzke, Sebastian; Brennhovd, Bjørn; Seierstad, Therese & Lyng, Heidi (2018). Combined MR imaging of oxygen consumption and supply reveals tumor hypoxia and aggressiveness in prostate cancer patients. Cancer Research.  ISSN 0008-5472.  78(16), s 4774- 4785 . doi: 10.1158/0008-5472.CAN-17-3806
  • Kalanxhi, Ert; Meltzer, Sebastian; Schou, Jakob Vasehus; Larsen, Finn Ole; Dueland, Svein; Flatmark, Kjersti; Jensen, Benny Vittrup; Hole, Knut Håkon; Seierstad, Therese; Redalen, Kathrine; Nielsen, Dorte Lisbet & Ree, Anne Hansen (2018). Systemic immune response induced by oxaliplatin-based neoadjuvant therapy favours survival without metastatic progression in high-risk rectal cancer. British Journal of Cancer.  ISSN 0007-0920.  118(10), s 1322- 1328 . doi: 10.1038/s41416-018-0085-y Full text in Research Archive.
  • Tulipan, Andreas Julius; Hole, Knut Håkon; Vlatkovic, Ljiljana; Rootwelt-Revheim, Mona-Elisabeth; Reijnen, Jeroen Sebastiaan; Willoch, Frode; Seierstad, Therese & Lilleby, Wolfgang (2018). Localization of radio-recurrence within the prostate: anti-3-18F-FACBC PET/CT compared with multiparametric MRI using histopathology as reference standard. Acta Radiologica.  ISSN 0284-1851.  s 1- 11 . doi: 10.1177/0284185118810977
  • Tulipan, Andreas Julius; Vlatkovic, Ljiljana; Malinen, Eirik; Brennhovd, Bjørn; Hole, Knut Håkon; Lie, Kathrine; Ragnum, Harald Bull; Rootwelt-Revheim, Mona-Elisabeth & Seierstad, Therese (2018). Comparison of time curves from dynamic 18F-fluciclovine positron emission tomography and dynamic contrast-enhanced magnetic resonance imaging for primary prostate carcinomas. Physics and imaging in radiation oncology (PIRO).  ISSN 2405-6316.  7, s 51- 57 . doi: 10.1016/j.phro.2018.09.003 Full text in Research Archive.
  • Bakke, Kine Mari; Hole, Knut Håkon; Dueland, Svein; Kotanska-Grøholt, Krystyna; Flatmark, Kjersti; Ree, Anne Hansen; Seierstad, Therese & Redalen, Kathrine Røe (2017). Diffusion-weighted magnetic resonance imaging of rectal cancer: tumour volume and perfusion fraction predict chemoradiotherapy response and survival. Acta Oncologica.  ISSN 0284-186X.  56(6), s 813- 818 . doi: 10.1080/0284186X.2017.1287951 Full text in Research Archive.
  • Lilleby, Wolfgang; Gaudernack, Gustav; Brunsvig, Paal Fr.; Vlatkovic, Ljiljana; Schulz, Melanie-Birte; Mills, Kate; Hole, Knut Håkon & Inderberg, Else Marit (2017). Phase I/IIa clinical trial of a novel hTERT peptide vaccine in men with metastatic hormone-naive prostate cancer. Cancer Immunology and Immunotherapy.  ISSN 0340-7004.  66(7), s 891- 901 . doi: 10.1007/s00262-017-1994-y
  • Torheim, Turid K Gjerstad; Malinen, Eirik; Hole, Knut Håkon; Lund, Kjersti Vassmo; Indahl, Ulf Geir; Lyng, Heidi; Kvaal, Knut & Futsæther, Cecilia Marie (2017). Autodelineation of cervical cancers using multiparametric magnetic resonance imaging and machine learning. Acta Oncologica.  ISSN 0284-186X.  56(6), s 806- 812 . doi: 10.1080/0284186X.2017.1285499
  • Dueland, Svein; Ree, Anne Hansen; Kotanska-Grøholt, Krystyna; Sælen, Marie Grøn; Folkvord, Sigurd; Hole, Knut Håkon; Seierstad, Therese; Larsen, Stein Gunnar; Giercksky, Karl-Erik; Wiig, Johan N.; Pedersen, Kjetil Boye & Flatmark, Kjersti (2016). Oxaliplatin-containing Preoperative Therapy in Locally Advanced Rectal Cancer: Local Response, Toxicity and Long-term Outcome. Clinical Oncology.  ISSN 0936-6555.  28(8), s 532- 539 . doi: 10.1016/j.clon.2016.01.014
  • Flatmark, Kjersti; Sælen, Marie Grøn; Hole, Knut Håkon; Abrahamsen, Torveig Weum; Fleten, Karianne Giller; Hektoen, Helga; Redalen, Kathrine Røe; Seierstad, Therese; Dueland, Svein & Ree, Anne Hansen (2016). Individual tumor volume responses to short-course oxaliplatin containing induction chemotherapy in locally advanced rectal cancer – Targeting the tumor for radiation sensitivity?. Radiotherapy and Oncology.  ISSN 0167-8140.  119(3), s 505- 511 . doi: 10.1016/j.radonc.2016.02.020 Show summary
  • Goscinski, Mariusz Adam; Hole, Knut Håkon; Tønne, Elin; Ryder, Truls; Kotanska-Grøholt, Krystyna & Flatmark, Kjersti (2016). Fibromatosis in vertical rectus abdominis myocutaneous flap imitating tumor recurrence after surgery for locally advanced rectal cancer: Case report. World Journal of Surgical Oncology.  ISSN 1477-7819.  14 . doi: 10.1186/s12957-016-0818-4
  • Redalen, Kathrine Røe; Sitter, Beathe; Bathen, Tone Frost; Kotanska-Grøholt, Krystyna; Hole, Knut Håkon; Dueland, Svein; Flatmark, Kjersti; Ree, Anne Hansen & Seierstad, Therese (2016). High tumor glycine concentration is an adverse prognostic factor in locally advanced rectal cancer. Radiotherapy and Oncology.  ISSN 0167-8140.  118(2), s 393- 398 . doi: 10.1016/j.radonc.2015.11.031
  • Lilleby, Wolfgang; Narrang, Amol; Tafjord, Gunnar; Vlatkovic, Ljiljana; Russnes, Kjell Magne; Stensvold, Andreas; Hole, Knut Håkon; Tran, Phuoc & Eilertsen, Karsten (2015). Favorable outcomes in locally advanced and node positive prostate cancer patients treated with combined pelvic IMRT and androgen deprivation therapy. Radiation Oncology.  ISSN 1748-717X.  10(1) . doi: 10.1186/s13014-015-0540-3
  • Ragnum, Harald Bull; Vlatkovic, Ljiljana; Lie, Kathrine; Axcrona, Eugen Jan Karol; Halle, Cathinka Lønning; Frikstad, Kari-Anne; Hole, Knut Håkon; Seierstad, Therese & Lyng, Heidi (2015). The tumour hypoxia marker pimonidazole reflects a transcriptional programme associated with aggressive prostate cancer. British Journal of Cancer.  ISSN 0007-0920.  112, s 382- 390 . doi: 10.1038/bjc.2014.604
  • Seierstad, Therese; Hole, Knut Håkon; Kotanska-Grøholt, Krystyna; Dueland, Svein; Ree, Anne Hansen; Flatmark, Kjersti & Redalen, Kathrine Røe (2015). MRI volumetry for prediction of tumour response to neoadjuvant chemotherapy followed by chemoradiotherapy in locally advanced rectal cancer. British Journal of Radiology.  ISSN 0007-1285.  88:20150097(1051) . doi: 10.1259/bjr.20150097
  • Switlyk, Marta Daniela; Kongsgaard, Ulf; Skjeldal, Sigmund; Hald, John K; Hole, Knut Håkon; Knutstad, Kjetil & ZAIKOVA, OLGA (2015). Prognostic factors in patients with symptomatic spinal metastases and normal neurological function. Clinical Oncology.  ISSN 0936-6555.  27(4), s 213- 221 . doi: 10.1016/j.clon.2015.01.002
  • Andersen, Erlend K F; Hole, Knut Håkon; Lund, Kjersti Vassmo; Sundfør, Kolbein; Kristensen, Gunnar S Balle; Lyng, Heidi & Malinen, Eirik (2013). Pharmacokinetic parameters derived from dynamic contrast enhanced MRI of cervical cancers predict chemoradiotherapy outcome. Radiotherapy and Oncology.  ISSN 0167-8140.  107(1), s 117- 122 . doi: 10.1016/j.radonc.2012.11.007
  • Hole, Knut Håkon; Axcrona, Karol; Lie, Kathrine; Vlatkovic, Ljiljana; Geier, Oliver; Brennhovd, Bjørn; Knutstad, Kjetil; Olsen, Dag Rune & Seierstad, Therese (2013). Routine pelvic MRI using phased-array coil for detection of extraprostatic tumour extension: accuracy and clinical significance. European Radiology.  ISSN 0938-7994.  23(4), s 1158- 1166 . doi: 10.1007/s00330-012-2669-x
  • Hole, Knut Håkon; Larsen, Stein Gunnar; Kotanska-Grøholt, Krystyna; Giercksky, Karl-Erik & Ree, Anne Hansen (2013). Magnetic resonance-guided histopathology for improved accuracy of tumor response evaluation of neoadjuvant treatment in organ-infiltrating rectal cancer. Radiotherapy and Oncology.  ISSN 0167-8140.  107(2), s 178- 183 . doi: 10.1016/j.radonc.2013.03.017
  • Andersen, Erlend K F; Hole, Knut Håkon; Lund, Kjersti Vassmo; Sundfør, Kolbein; Kristensen, Gunnar S Balle; Lyng, Heidi & Malinen, Eirik (2012). Dynamic Contrast-Enhanced MRI of Cervical Cancers: Temporal Percentile Screening of Contrast Enhancement Identifies Parameters for Prediction of Chemoradioresistance. International Journal of Radiation Oncology, Biology, Physics.  ISSN 0360-3016.  82(3), s E485- E492 . doi: 10.1016/j.ijrobp.2011.05.050
  • Dimmen, Magne; Vlatkovic, Ljiljana; Hole, Knut Håkon; Nesland, Jahn M; Brennhovd, Bjørn & Axcrona, Karol (2012). Transperineal prostate biopsy detects significant cancer in patients with elevated prostate-specific antigen (PSA) levels and previous negative transrectal biopsies. BJU International.  ISSN 1464-4096.  110(2 Pt 2), s E69- 75 . doi: 10.1111/j.1464-410x.2011.10759.x
  • Fosså, Alexander; Fiskvik, Idun Hege; Kolstad, Arne; Lauritzsen, Grete Fossum; Aurlien, Ellen; Blystad, Anne Kirsti; Hole, Knut Håkon; Ikonomou, Ida Merete Münster & Holte, Harald (2012). Two escalated followed by six standard BEACOPP in advanced-stage high-risk classical Hodgkin lymphoma: high cure rates but increased risk of aseptic osteonecrosis. Annals of Oncology.  ISSN 0923-7534.  23(5), s 1254- 1259 . doi: 10.1093/annonc/mdr385
  • Switlyk, Marta Daniela; Hole, Knut Håkon; Skjeldal, Sigmund; Hald, John K; Knutstad, Kjetil; Seierstad, Therese & ZAIKOVA, OLGA (2012). MRI and neurological findings in patients with spinal metastases. Acta Radiologica.  ISSN 0284-1851.  53(10), s 1164- 1172 . doi: 10.1258/ar.2012.120442
  • Fangberget, Anne; Nilsen, Line; Hole, Knut Håkon; Holmen, Marit Muri; Engebråten, Olav; Naume, Bjørn; Smith, Hans-Jørgen; Olsen, Dag Rune & Seierstad, Therese (2011). Neoadjuvant chemotherapy in breast cancer-response evaluation and prediction of response to treatment using dynamic contrast-enhanced and diffusion-weighted MR imaging. European Radiology.  ISSN 0938-7994.  21(6), s 1188- 1199 . doi: 10.1007/s00330-010-2020-3
  • Hjortland, Geir Olav; Meza, Leonardo Zepeda; Beiske, Klaus; Ree, Anne Hansen; Tveito, Siri; Høifødt, Hanne Kleppe; Bøhler, Per J.; Hole, Knut Håkon; Myklebost, Ola; Fodstad, Øystein; Smeland, Sigbjørn & Hovig, Eivind (2011). Genome wide single cell analysis of chemotherapy resistant metastatic cells in a case of gastroesophageal adenocarcinoma. BMC Cancer.  ISSN 1471-2407.  11 . doi: 10.1186/1471-2407-11-455
  • Folkvord, Sigurd; Flatmark, Kjersti; Dueland, Svein; de Wijn, Rik; Grøholt, Krystyna Kotanska; Hole, Knut Håkon; Nesland, Jahn M; Ruijtenbeek, Rob; Boender, Piet J.; Johansen, Marianne; Giercksky, Karl-Erik & Ree, Anne Hansen (2010). Prediction of response to preoperative chemoradiotherapy in rectal cancer by multiplex kinase activity profiling. International Journal of Radiation Oncology, Biology, Physics.  ISSN 0360-3016.  78(2), s 555- 562 . doi: 10.1016/j.ijrobp.2010.04.036
  • Ree, Anne Hansen; Dueland, Svein; Folkvord, Sigurd; Hole, Knut Håkon; Seierstad, Therese; Johansen, Marianne; Abrahamsen, Torveig Weum & Flatmark, Kjersti (2010). Vorinostat, a histone deacetylase inhibitor, combined with pelvic palliative radiotherapy for gastrointestinal carcinoma: the Pelvic Radiation and Vorinostat (PRAVO) phase 1 study. The Lancet Oncology.  ISSN 1470-2045.  11(5), s 459- 464 . doi: 10.1016/S1470-2045(10)70058-9
  • Larsen, Stein Gunnar; Wiig, Johan N.; Emblemsvaag, HL; Grøholt, Krystyna Kotanska; Hole, Knut Håkon; Bentsen, Annette; Dueland, Svein; Vetrhus, T. & Giercksky, Karl-Erik (2009). Extended total mesorectal excision in locally advanced rectal cancer (T4a) and the clinical role of MRI-evaluated neo-adjuvant downstaging. Colorectal Disease.  ISSN 1462-8910.  11(7), s 759- 767 . doi: 10.1111/j.1463-1318.2008.01649.x
  • Seierstad, Therese; Hole, Knut Håkon; Sælen, Erik; Ree, Anne Hansen & Flatmark, Kjersti (2009). MR-guided simultaneous integrated boost in preoperative radiotherapy of locally advanced rectal cancer following neoadjuvant chemotherapy. Radiotherapy and Oncology.  ISSN 0167-8140.  93(2), s 279- 284 Show summary
  • Seierstad, Therese; Hole, Knut Håkon; Sælen, Erik; Ree, Anne Hansen; Flatmark, Kjersti & Malinen, Eirik (2009). MR-guided simultaneous integrated boost in preoperative radiotherapy of locally advanced rectal cancer following neoadjuvant chemotherapy. Radiotherapy and Oncology.  ISSN 0167-8140.  93(2), s 279- 284
  • Lillleby, Wolfgang; Axcrona, Karol; Alfsen, G. Cecilie; Urnes, Thomas & Hole, Knut Håkon (2007). Diagnosis and treatment of primary signet-ring cell carcinoma of the prostate.. Acta Oncologica.  ISSN 0284-186X.  46, s 1195- 1197
  • Hoff, Geir; Wiig, Johan N.; Reed, Wenche; Hole, Knut Håkon; Scheistrøen, Marit & Henriksen, Halvor (2005). Short stricture of the rectum regressing on discontination of hormone replacement therapy: Endoscopic appearance, multiple biopsies and clinical improvement insufficient for diagnosis. Scandinavian Journal of Gastroenterology.  ISSN 0036-5521.  40(3), s 365- 367 . doi: 10.1080/00365520510011614

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  • Bakke, Kine Mari; Hole, Knut Håkon; Dueland, Svein; Grøholt, Krystyna Kotanska; Ree, Anne Hansen; Flatmark, Kjersti; Seierstad, Therese & Redalen, Kathrine Røe (2017). Diffusion-weighted MRI of rectal cancer: baseline tumour perfusion fraction predicts chemoradiotherapy response and survival.
  • Torheim, Turid K Gjerstad; Malinen, Eirik; Hole, Knut Håkon; Lund, Kjersti Vassmo; Indahl, Ulf Geir; Kvaal, Knut; Lyng, Heidi & Futsæther, Cecilia Marie (2017). Autodelineation of cervical cancers using multiparametric MRI and machine learning.
  • Bakke, Kine Mari; Hole, Knut Håkon; Dueland, Svein; Flatmark, Kjersti; Ree, Anne Hansen; Seierstad, Therese & Redalen, Kathrine Røe (2016). Tumour perfusion estimated from diffusion-weighted MRI of rectal cancer – an indirect marker of tumour hypoxia?.
  • Bakke, Kine Mari; Seierstad, Therese; Hole, Knut Håkon; Dueland, Svein; Flatmark, Kjersti; Ree, Anne Hansen & Redalen, Kathrine Røe (2016). Histogram analysis of ADCs from DWMRI predicts tumour response and survival for rectal cancer.
  • Goscinski, Mariusz Adam; Hole, Knut Håkon; Tønne, Elin; Ryder, Truls; Kotanska-Grøholt, Krystyna & Flatmark, Kjersti (2016). Fibromatosis in vertical rectus abdominis myocutaneous flap imitating tumor recurrence after surgery for locally advanced rectal cancer: case report. World Journal of Surgical Oncology.  ISSN 1477-7819.  14(63) . doi: 10.1186/s12957-016-0818-4
  • Redalen, Kathrine Røe; Sitter, Beathe; Bathen, Tone Frost; Grøholt, Krystyna Kotanska; Hole, Knut Håkon; Dueland, Svein; Flatmark, Kjersti; Ree, Anne Hansen & Seierstad, Therese (2016). High tumour glycine concentration – an adverse prognostic factor in locally advanced rectal cancer.
  • Bakke, Kine Mari; Seierstad, Therese; Hole, Knut Håkon; Ree, Anne Hansen & Redalen, Kathrine Røe (2015). Histogram analysis of apparent diffusion coefficients from diffusion-weighted MRI during neoadjuvant treatment of locally advanced rectal cancer predicts histologic tumor response and survival.
  • Seierstad, Therese; Hole, Knut Håkon; Grøholt, Krystyna Kotanska; Dueland, Svein; Ree, Anne Hansen; Flatmark, Kjersti & Redalen, Kathrine Røe (2015). Prediction of response to neoadjuvant chemotherapy followed by chemoradiotherapy in rectal cancer by MRI volumetry. Radiotherapy and Oncology.  ISSN 0167-8140.  115, s S350
  • Torheim, Turid K Gjerstad; Malinen, Eirik; Hole, Knut Håkon; Lund, Kjersti Vassmo; Indahl, Ulf Geir; Kvaal, Knut; Lyng, Heidi & Futsæther, Cecilia Marie (2015). Cervical tumour segmentation using multi-sequence MRI and linear discriminant analysis.
  • Raabe, Nils Kristian; Sundfør, Kolbein; Hole, Knut Håkon; Djupvik, Linda Holth; Larsen, Stein Gunnar & Dueland, Svein (2014). Høydoserate brakyterapi mot residiverende endetarmskreft etter konvensjonell residivbehandling. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  134(20), s 1929- 1920 . doi: 10.4045/tidsskr.14.1162
  • Revheim, Mona Elisabeth; Hole, Knut Håkon; Bruland, Øyvind; Reitan, Edmund; Bjerkehagen, Bodil; Julsrud, Lars & Seierstad, Therese (2014). Multimodal functional imaging for early response assessment in GIST patients treated with imatinib. Acta Oncologica.  ISSN 0284-186X.  53(1), s 143- 148 . doi: 10.3109/0284186X.2013.798428
  • Andersen, Erlend K F; Hole, Knut Håkon; Lund, Kjersti Vassmo; Kristensen, Gunnar S Balle; Lyng, Heidi & Malinen, Eirik (2012). IMPACT OF TUMOR DELINEATION ERRORS ON OUTCOME PREDICTION BASED ON DCE-MRI OF CERVICAL CANCER PATIENTS RECEIVING RT. Radiotherapy and Oncology.  ISSN 0167-8140.  103, s 72- 72
  • Revheim, Mona-Elisabeth; Hole, Knut Håkon; Bruland, Øyvind Sverre; Haugland, Hans Kristian; Hall, Kirsten Sundby & Seierstad, Therese (2011). DW MRI for evaluation of treatment response to imatinib in a rectal gastrointestinal stromal tumour. Acta Oncologica.  ISSN 0284-186X.  50(1), s 148- 150 . doi: 10.3109/0284186X.2010.516273
  • Larsen, Stein Gunnar; Hole, Knut Håkon; Kotanska-Grøholt, Krystyna; Dueland, Svein & Giercksky, Karl-Erik (2010). THE PRE-TREATMENT MRI PREDICTS THE NEED FOR EXTENDED TOTAL MESORECTAL EXCISION (ETME) IN T4A RECTAL CANCER. Annals of Oncology.  ISSN 0923-7534.  21, s 60- 60

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Published Jan. 16, 2019 12:32 PM - Last modified Feb. 11, 2019 11:30 AM