Mari Aksnes
Research interests
I am interested in the biological changes associated with neurodegeneration; how does neurodegeneration develop in the brain and how does it affect brain function? Further understanding of these processes can hopefully contribute to better identification, treatment and prevention of neurodegenerative diseases like Alzheimer's disease.
In my postdoctoral project, FEMDEM, I aim to understand more about why twice as many women as men get Alzheimer's disease. It is well established that one factor is women's more advanced age as a group, but what is the role of sex hormones and other sex differences? In FEMDEM I will explore the interaction between sex, sex hormones, genetics and biomarkers for Alzheimer's disease in order to learn more about the mechanisms underlying sex differences in Alzheimer's disease.
Background
Education
- 2018 - 2022
University of Oslo, PhD fellow in Geriatrics and Neuroscience
"Amyloidogenic nanoplaques as a potential biomarker for Alzheimer's disease" - 2015-2017
Norwegian University of Science and Technology, MSc in Neuroscience
"Effect of cerebrospinal fluid from patients with Alzheimer's disease on protein expression in the hippocampal region of a transgenic rat model of Alzheimer's disease" - 2012-2015
University of Durham, BSc in Psychology
Work experience
- 2018 - 2022 University of Oslo,
PhD fellow in Geriatrics and Neuroscience, Ullevål Dementia Research Group - 2018 Oslo University Hospital, Maria Korsnes' research group
Research assistant - 2017 - 2018 Forskerfabrikken
Course leader for two "Researcher"-courses for school children - 2017 - Oslo New College
Supervisor and examinator for the Psychology Department
Publications
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Aksnes, Mari; Aass, Hans Christian Dalsbotten; Tiiman, Ann; Terenius, Lars; Bogdanovic, Nenad & Vukojević, Vladana [Show all 7 contributors for this article] (2022). Serum Amyloidogenic Nanoplaques and Cytokines in Alzheimer's Disease: Pilot Study in a Small Naturalistic Memory Clinic Cohort. Journal of Alzheimer's Disease. ISSN 1387-2877. 86(3), p. 1459–1470. doi: 10.3233/JAD-215504. Full text in Research Archive
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Aksnes, Mari; Aass, Hans Christian Dalsbotten; Tiiman, Ann; Edwin, Trine Holt; Terenius, Lars & Bogdanovic, Nenad [Show all 8 contributors for this article] (2021). Associations of cerebrospinal fluid amyloidogenic nanoplaques with cytokines in Alzheimer's disease. Translational Neurodegeneration. ISSN 2096-6466. 10(1). doi: 10.1186/s40035-021-00244-3. Full text in Research Archive
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Aksnes, Mari; Tiiman, Ann; Edwin, Trine Holt; Terenius, Lars; Bogdanovic, Nenad & Vukojevic, Vladana [Show all 7 contributors for this article] (2021). Comparison of cerebrospinal fluid amyloidogenic nanoplaques with core biomarkers of Alzheimer's disease. Frontiers in Aging Neuroscience. ISSN 1663-4365. 12:608628, p. 1–11. doi: 10.3389/fnagi.2020.608628. Full text in Research Archive
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Aksnes, Mari; Müller, Ebba Gløersen; Tiiman, Ann; Edwin, Trine Holt; Terenius, Lars & Rootwelt-Revheim, Mona-Elisabeth [Show all 9 contributors for this article] (2020). Amyloidogenic nanoplaques in cerebrospinal fluid: Relationship to amyloid brain uptake and clinical Alzheimer's disease in a memory clinic cohort. Journal of Alzheimer's Disease. ISSN 1387-2877. 77(2), p. 831–842. doi: 10.3233/JAD-200237. Full text in Research Archive Show summary