Pål Dag Line

• Chávez-Villa, Mariana; Ruffolo, Luis I.; Line, Pål Dag; Dueland, Svein; Tomiyama, Koji & Hernandez-Alejandro, Roberto (2024). Emerging Role of Liver Transplantation for Unresectable Colorectal Liver Metastases. Journal of Clinical Oncology. ISSN 0732-183X. 42(10), p. 1098–1101. doi: 10.1200/JCO.23.01781.
• Grut, Harald; Line, Pål Dag; Syversveen, Trygve & Dueland, Svein (2023). Metabolic Tumor Volume from ¹⁸F-FDG PET/CT in Combination with Radiologic Measurements to Predict Long-Term Survival Following Transplantation for Colorectal Liver Metastases. Cancers. ISSN 2072-6694. 16(1). doi: 10.3390/cancers16010019.
• Line, Pål Dag & Dueland, Svein (2023). Transplantation for colorectal liver metastasis. Current Opinion in Organ Transplantation. ISSN 1087-2418. 29(1), p. 23–29. doi: 10.1097/MOT.0000000000001126. Full text in Research Archive
• Farnes, Ingvild; Kleive, Dyre; Verbeke, Caroline Sophie; Aabakken, Lars; Issa-Epe, Aart Imran & Småstuen, Milada Cvancarova [Show all 10 contributors for this article] (2023). Resection rates and intention-to-treat outcomes in borderline and locally advanced pancreatic cancer: real-world data from a population-based, prospective cohort study (NORPACT-2). BJS Open. ISSN 2474-9842. 7:zrad137(6), p. 1–10. doi: 10.1093/bjsopen/zrad137. Full text in Research Archive
• Rydenfelt, Kristina Elisabeth; Kjøsen, Gisle; Horneland, Rune; Ludviksen, Judith K; Jenssen, Trond & Line, Pål Dag [Show all 10 contributors for this article] (2023). Local Postoperative Graft Inflammation in Pancreas Transplant Patients With Early Graft Thrombosis. Transplantation direct. ISSN 2373-8731. 10(1). doi: 10.1097/TXD.0000000000001567. Full text in Research Archive
• Khan, Ammar; Fosby, Bjarte; Labori, Knut Jørgen; Lanari, Jacopo; Dorenberg, Eric & Line, Pål Dag (2023). Management of Coeliac and Hepatic Artery Aneurysms: A Single Institution Experience of 84 Cases. European Journal of Vascular and Endovascular Surgery. ISSN 1078-5884. 66(6), p. 814–820. doi: 10.1016/j.ejvs.2023.09.032. Full text in Research Archive
• Martins Fernandes, Eduardo de Souza; de Souza, Gabrielle Oliveira; Braga, Eduardo Pinho; Leite Furtado, Rodrigo Lopes; Corrêa, Raphael Rodrigues & Queiroz, Camila Tobias [Show all 10 contributors for this article] (2023). AN EXPERIENCE ON LIVING DONOR LIVER TRANSPLANTATION FOR COLORECTAL LIVER METASTASIS IN SOUTH AMERICA: A NEW ERA IN TRANSPLANT ONCOLOGY. Arquivos Brasileiros de Cirurgia Digestiva (ABCD). ISSN 0102-6720. 36. doi: 10.1590/0102-672020230046e1764.
• Åberg, Fredrik; Sallinen, Ville; Tuominen, Samuli; Adam, René; Karam, Vincent & Mirza, Darius [Show all 18 contributors for this article] (2023). Cyclosporine vs. tacrolimus after liver transplantation for primary sclerosing cholangitis – a propensity score-matched intention-to-treat analysis. Journal of Hepatology. ISSN 0168-8278. doi: 10.1016/j.jhep.2023.08.031. Full text in Research Archive
• Carbone, M.; Della Penna, Penna; Mazzarelli, C.; De Martin, Martin; Villard, C. & Bergquist, A. [Show all 20 contributors for this article] (2023). Liver Transplantation for Primary Sclerosing Cholangitis (PSC) With or Without Inflammatory Bowel Disease (IBD)—A European Society of Organ Transplantation (ESOT) Consensus Statement. Transplant International. ISSN 0934-0874. 36. doi: 10.3389/ti.2023.11729. Full text in Research Archive
• Dueland, Svein; Smedman, Tor Magnus; Syversveen, Trygve; Grut, Harald; Hagness, Morten & Line, Pål Dag (2023). Long-Term Survival, Prognostic Factors, and Selection of Patients with Colorectal Cancer for Liver Transplant: A Nonrandomized Controlled Trial. JAMA Surgery. ISSN 2168-6254. 158(9). doi: 10.1001/jamasurg.2023.2932.
• Shi, Jihua; Cheng, Nuo; Zhang, Wen; Jin, Qiang; Guo, Wen-Zhi & Ge, Guang-Bo [Show all 9 contributors for this article] (2023). Air-ventilated normothermic machine perfusion alleviates hepatic injury from DCD rat through CYP1A2. Heliyon. ISSN 2405-8440. 9(8). doi: 10.1016/j.heliyon.2023.e19150. Full text in Research Archive
• Braadland, Peder Rustøen; Bergquist, Annika; Kummen, Martin; Bossen, Lars; Engesæter, Lise Katrine & Reims, Henrik Mikael [Show all 21 contributors for this article] (2023). Clinical and biochemical impact of vitamin B6 deficiency in primary sclerosing cholangitis before and after liver transplantation. Journal of Hepatology. ISSN 0168-8278. 79(4), p. 955–966. doi: 10.1016/j.jhep.2023.05.038. Full text in Research Archive
• Andersen, Ina Marie; Reims, Henrik Mikael; Grzyb, Krzysztof; Fevang, Børre; Melum, Espen & Aukrust, Pål [Show all 10 contributors for this article] (2023). Long-term survival after liver transplantation in patients with common variable immunodeficiency. Liver transplantation. ISSN 1527-6465. 29(8), p. 894–899. doi: 10.1097/LVT.0000000000000130.
• Bergsmark, Thomas; Engesæter, Lise Katrine; Rasmussen, Allan; Bennet, William; Nordin, Arno & Pall, Virge [Show all 9 contributors for this article] (2023). Long-term survival after liver transplantation for alcohol-related liver disease in the Nordic countries. Scandinavian Journal of Gastroenterology. ISSN 0036-5521. 58(8), p. 923–930. doi: 10.1080/00365521.2023.2184193.
• Rydenfelt, Kristina Elisabeth; Kjøsen, Gisle; Horneland, Rune; Ludviksen, Judith K; Jenssen, Trond & Line, Pål Dag [Show all 10 contributors for this article] (2023). Thromboinflammatory response is increased in pancreas transplant alone versus simultaneous pancreas-kidney transplantation and early pancreas graft thrombosis is associated with complement activation. Frontiers in Immunology. ISSN 1664-3224. 14. doi: 10.3389/fimmu.2023.1044444. Full text in Research Archive
• Eshmuminov, Dilmurodjon; Studer, Debora J; Lopez, Victor Lopez; Schneider, Marcel Andre; Lerut, Jan & Lo, Mary [Show all 35 contributors for this article] (2022). Controversy Over Liver Transplantation or Resection for Neuroendocrine Liver Metastasis: Tumor Biology Cuts the Deal. Annals of Surgery. ISSN 0003-4932. 277(5). doi: 10.1097/SLA.0000000000005663.
• Solheim, Jon Magnus Aarstrand; Dueland, Svein; Line, Pål Dag & Hagness, Morten (2022). Transplantation for Nonresectable Colorectal Liver Metastases: Long-Term Follow-Up of the First Prospective Pilot Study. Annals of Surgery. ISSN 0003-4932. 278(2), p. 239–245. doi: 10.1097/SLA.0000000000005703.
• Settmacher, Utz; Ali-Deeb, Aladdin; Coubeau, Laurent; Cillo, Umberto; Line, Pål Dag & Guba, Markus [Show all 8 contributors for this article] (2022). Auxilliary Liver Transplantation According to the RAPID Procedure in Noncirrhotic Patients Technical Aspects and Early Outcomes. Annals of Surgery. ISSN 0003-4932. 277(2), p. 305–312. doi: 10.1097/SLA.0000000000005726.
• Salcedo, Magdalena; Vinaixa, Carmen; Javle, Milind; Trapero-Marugan, Maria; Bustamante, Javier & Line, Pål Dag (2022). Evaluation and Management of Liver Transplant Candidates With Prior Nonhepatic Cancer: Guidelines From the ILTS/SETH Consensus Conference. Transplantation. ISSN 0041-1337. 106(1), p. e3–e11. doi: 10.1097/TP.0000000000003997.
• Line, Pål Dag (2022). Liver transplantation for colorectal secondaries: on the way to validation. Current Opinion in Organ Transplantation. ISSN 1087-2418. 27(4), p. 329–336. doi: 10.1097/MOT.0000000000000977. Full text in Research Archive
• Grut, Harald; Line, Pål Dag; Syversveen, Trygve & Dueland, Svein (2022). Metabolic tumor volume predicts long-term survival after transplantation for unresectable colorectal liver metastases: 15 years of experience from the SECA study. Annals of Nuclear Medicine. ISSN 0914-7187. 36(12), p. 1073–1081. doi: 10.1007/s12149-022-01796-8. Full text in Research Archive
• Dueland, Svein; Smedman, Tor Magnus; Grut, Harald; Syversveen, Trygve; Jørgensen, Lars Hilmar & Line, Pål Dag (2022). PET-Uptake in Liver Metastases as Method to Predict Tumor Biological Behavior in Patients Transplanted for Colorectal Liver Metastases Developing Lung Recurrence. Cancers. ISSN 2072-6694. 14(20). doi: 10.3390/cancers14205042. Full text in Research Archive
• Hou, Jie; Liavåg, Olav Magnus Ivar; Færden, Ida Høy; Martinsen, Ørjan Grøttem; Tønnessen, Tor Inge & Line, Pål Dag [Show all 10 contributors for this article] (2022). Utilization of dielectric properties for assessment of liver ischemia-reperfusion injury in vivo and during machine perfusion. Scientific Reports. ISSN 2045-2322. 12(1). doi: 10.1038/s41598-022-14817-3. Full text in Research Archive
• Smedman, Tor Magnus; Guren, Tormod Kyrre; Tveit, Magne Kjell; Thomsen, Maria; Andersen, Marit Helen & Line, Pål Dag [Show all 7 contributors for this article] (2022). Health-Related Quality of Life in Colorectal Cancer Patients Treated With Liver Transplantation Compared to Chemotherapy. Transplant International. ISSN 0934-0874. 35. doi: 10.3389/ti.2022.10404. Full text in Research Archive
• Haflidadottir, Svanhildur; Østensen, Inger Anniken Bjørnstad; Matthews, Iren; Line, Pål Dag & Almaas, Runar (2022). Mycophenolate mofetil use is associated with reduced incidence of food allergy in liver transplanted children. Journal of Pediatric Gastroenterology and Nutrition - JPGN. ISSN 0277-2116. 75(2), p. 138–144. doi: 10.1097/MPG.0000000000003509.
• Bjørnelv, Gudrun Maria Waaler; Zolic-Karlsson, Zinajda; Dueland, Svein; Line, Pål Dag & Aas, Eline (2022). Cost-effectiveness of liver transplantation versus last-resort systemic therapy for colorectal liver metastases. British Journal of Surgery. ISSN 0007-1323. 109(6), p. 483–485. doi: 10.1093/bjs/znac022. Full text in Research Archive
• Fodor, Margot; Zoller, Heinz; Oberhuber, Rupert; Sucher, Robert; Seehofer, Daniel & Cillo, Umberto [Show all 9 contributors for this article] (2022). The need to update endpoints and outcome analysis in the rapidly changing field of liver transplantation. Transplantation. ISSN 0041-1337. 106(5), p. 938–949. doi: 10.1097/TP.0000000000003973.
• Kjøsen, Gisle; Horneland, Rune; Nordheim, Espen; Aandahl, Einar Martin; Line, Pål Dag & Rydenfelt, Kristina Elisabeth [Show all 9 contributors for this article] (2022). Validating the US pancreas donor risk index in a Norwegian population, a retrospective observational study. Scandinavian Journal of Gastroenterology. ISSN 0036-5521. 57(3), p. 345–351. doi: 10.1080/00365521.2021.2012590. Full text in Research Archive Show summary

  OBJECTIVES Despite advances in immunosuppression and surgical technique, pancreas transplantation is still associated with a significant graft loss rate. The Pancreas Donor Risk Index (PDRI) is a pre-transplant scoring tool derived from a US population. We sought to validate the PDRI in a Norwegian population. METHODS We retrospectively retrieved donor data for 344 pancreas transplants undertaken in Norway between 2000 and 2019, utilising the Scandiatransplant database, and matched these to the respective recipients. The PDRI score was calculated for each transplanted pancreas, these were then stratified into quintiles. The association between the PDRI quintiles and 1-year graft survival was calculated, and this was repeated for the different types of pancreas transplantation. The association between PDRI as a continuous variable, and graft survival was determined. Donor and recipient data were compared to the original US population. RESULTS The overall 1-year graft survival was 82.7%. There were no significant differences in survival between the different PDRI quintiles. When viewed as a continuous variable, increased PDRI score was not associated with decreased graft survival. Significant differences between the Norwegian and US populations were found. CONCLUSIONS When applied to a Norwegian population, the PDRI score was unable to predict 1-year graft survival.

• Sparrelid, Ernesto; Thorsen, Trygve; Sauter, Christina; Jorns, Carl; Stål, Per & Nordin, Arno [Show all 14 contributors for this article] (2022). Liver transplantation in patients with post-hepatectomy liver failure – A Northern European multicenter cohort study. HPB. ISSN 1365-182X. doi: 10.1016/j.hpb.2021.12.005. Full text in Research Archive
• Østensen, Inger Anniken Bjørnstad; Skarbø, Anne-Britt; Sanengen, Truls; Line, Pål Dag & Almaas, Runar (2022). Impaired Neurocognitive Performance in Children After Liver Transplantation. Journal of Pediatrics. ISSN 0022-3476. doi: 10.1016/j.jpeds.2021.12.033. Full text in Research Archive Show summary

  Objectives To assess longitudinal neurocognitive development after liver transplantation and evaluate factors associated with neurocognitive performance. Study design Data from neurocognitive testing of 65 children (aged <18 years) who underwent liver transplantation at Oslo University Hospital between 1995 and 2018 were collected from the testing program after transplantation. The parent-reported version of the Behavior Rating Inventory of Executive Function was used to assess executive function. Results A total of 104 neurocognitive tests were conducted on 65 patients. At the first test, conducted at a median of 4.1 years (IQR, 1.5-5.3 years) after transplantation and at a median age of 6.7 years (IQR, 5.4-10.5 years), the mean full-scale IQ (FSIQ) was 91.7 ± 14, and the mean verbal comprehension index was 92.0 ± 14.5. In the 30 patients tested more than once, there was no significant difference in FSIQ between the first test at a median age of 5.8 years (IQR, 5.2-8.5 years) and the last test at a median age of 10.8 years (IQR, 9.8-12.9 years) (87.4 ± 12.9 vs 88.5 ± 13.2; P = .58). Compared with the patients who underwent transplantation a age >1 year (n = 35), those who did so at age <1 year (n = 30) had a lower FSIQ (87.1 ± 12.6 vs 96.6 ± 13.8; P = .005) and lower verbal comprehension index (87.3 ± 13.8 vs 95.4 ± 13.0; P = .020). Age at transplantation (P = .005; adjusted for cholestasis: P = .038) and transfusion of >80 mL/kg (P = .004; adjusted for age at transplantation: P = .046) were associated with FSIQ. Conclusions Young age at transplantation and large blood transfusions during transplantation are risk factors for poor neurocognitive performance later in life. Children who undergo transplantation before 1 year of age have significantly lower neurocognitive performance compared with those who do so later in childhood. Cognitive performance did not improve over time after transplantation.

• Lanari, Jacopo; Hagness, Morten; Sartori, Alessandra; Rosso, Eugenia; Gringeri, Enrico & Dueland, Svein [Show all 8 contributors for this article] (2021). Liver transplantation versus liver resection for colorectal liver metastasis: a survival benefit analysis in patients stratified according to tumor burden score. Transplant International. ISSN 0934-0874. doi: 10.1111/tri.13981. Full text in Research Archive
• Dueland, Svein; Syversveen, Trygve; Hagness, Morten; Grut, Harald & Line, Pål Dag (2021). Liver transplantation for advanced liver-only colorectal metastases. British Journal of Surgery. ISSN 0007-1323. 108(12), p. 1402–1405. doi: 10.1093/bjs/znab196.
• Kjøsen, Gisle; Rydenfelt, Kristina Elisabeth; Horneland, Rune; Aandahl, Einar Martin; Line, Pål Dag & Dorenberg, Eric Jürgen [Show all 15 contributors for this article] (2021). Early detection of complications in pancreas transplants by microdialysis catheters, an observational feasibility study. PLOS ONE. ISSN 1932-6203. 16(3), p. 1–16. doi: 10.1371/journal.pone.0247615. Full text in Research Archive
• Grut, Harald; Line, Pål Dag; Labori, Knut Jørgen; Schulz, Anselm & Dueland, Svein (2021). Survival after liver resection and liver transplantation for colorectal liver metastases: a comparative analysis stratified by metabolic tumor volume assessed by 18F-FDG PET/CT. HPB. ISSN 1365-182X. doi: 10.1016/j.hpb.2021.11.015.
• Dueland, Svein; Yaqub, Sheraz; Syversveen, Trygve; Carling, Johan Ulrik; Hagness, Morten & Brudvik, Kristoffer Watten [Show all 7 contributors for this article] (2021). Survival Outcomes after Portal Vein Embolization and Liver Resection Compared with Liver Transplant for Patients with Extensive Colorectal Cancer Liver Metastases. JAMA Surgery. ISSN 2168-6254. 156(6), p. 550–557. doi: 10.1001/jamasurg.2021.0267.
• Berenguer, Marina; Di Maira, Tommaso; Baumann, Ulrich; Mirza, Darius F.; Heneghan, Michael A. & Klempnauer, Jurgen L. [Show all 16 contributors for this article] (2021). Characteristics, Trends, and Outcomes of Liver Transplantation for Primary Sclerosing Cholangitis in Female Versus Male Patients: An Analysis from the European Liver Transplant Registry. Transplantation. ISSN 0041-1337. p. 2255–2262. doi: 10.1097/TP.0000000000003542.
• Mueller, Matteo; Breuer, Eva; Mizuno, Takashi; Bartsch, Fabian; Ratti, Francesca & Benzing, Christian [Show all 63 contributors for this article] (2021). Perihilar Cholangiocarcinoma - Novel Benchmark Values for Surgical and Oncological Outcomes From 24 Expert Centers. Annals of Surgery. ISSN 0003-4932. 274(5), p. 780–788. doi: 10.1097/SLA.0000000000005103.
• Bonney, Glenn K.; Chew, Claire Alexandra; Lodge, Peter; Hubbard, Joleen; Halazun, Karim J. & Trunecka, Pavel [Show all 27 contributors for this article] (2021). Liver transplantation for non-resectable colorectal liver metastases: the International Hepato-Pancreato-Biliary Association consensus guidelines. The Lancet Gastroenterology and Hepatology. ISSN 2468-1253. 6(11), p. 933–946. doi: 10.1016/S2468-1253(21)00219-3.
• Lindholm, Espen; Bergmann, Gisli Björn; Haugaa, Håkon; Labori, Knut Jørgen; Yaqub, Sheraz & Bjørnbeth, Bjørn Atle [Show all 11 contributors for this article] (2021). Early detection of anastomotic leakage after pancreatoduodenectomy with microdialysis catheters: an observational Study. HPB. ISSN 1365-182X. 24(6), p. 901–909. doi: 10.1016/j.hpb.2021.10.020. Full text in Research Archive Show summary

  Background Microdialysis catheters can detect focal inflammation and ischemia, and thereby have a potential for early detection of anastomotic leakages after pancreatoduodenectomy. The aim was to investigate whether microdialysis catheters placed near the pancreaticojejunostomy can detect leakage earlier than the current standard of care. Methods Thirty-five patients with a median age 69 years were included. Two microdialysis catheters were placed at the end of surgery; one at the pancreaticojejunostomy, and one at the hepaticojejunostomy. Concentrations of glucose, lactate, pyruvate, and glycerol were analyzed hourly in the microdialysate during the first 24 h, and every 2–4 h thereafter. Results Seven patients with postoperative pancreatic fistulae (POPF) had significantly higher glycerol levels (P < 0.01) in the microdialysate already in the first postoperative samples. Glycerol concentrations >400 μmol/L during the first 12 postoperative hours detected patients with POPF with a sensitivity of 100% and a specificity of 93% (P < 0.001). After 24 h, lactate and lactate-to-pyruvate ratio were significantly higher (P < 0.05) and glucose was significantly lower (P < 0.05) in patients with POPF. Conclusion High levels of glycerol in microdialysate was an early detector of POPF. The subsequent inflammation was detected as increase in lactate and lactate-to-pyruvate ratio and a decrease in glucose (NCT03627559).

• Dueland, Svein; Smedman, Tor M.; Røsok, Bård Ingvald; Grut, Harald; Syversveen, Trygve & Jørgensen, Lars Hilmar [Show all 7 contributors for this article] (2021). Treatment of relapse and survival outcomes after liver transplantation in patients with colorectal liver metastases. Transplant International. ISSN 0934-0874. 34(11), p. 2205–2213. doi: 10.1111/tri.13995.
• Hausken, John; Haugaa, Håkon; Hagness, Morten; Line, Pål-Dag; Melum, Espen & Tønnessen, Tor Inge (2021). Thoracic Epidural Analgesia for Postoperative Pain Management in Liver Transplantation: A 10-year Study on 685 Liver Transplant Recipients. Transplantation direct. ISSN 2373-8731. 7(2), p. 1–6. doi: 10.1097/TXD.0000000000001101. Full text in Research Archive Show summary

  Background. Thoracic epidural analgesia (TEA) is not widely used for postoperative pain management in liver transplantation due to hepatic coagulopathy-related increased risk of inducing an epidural hematoma. However, an increasing number of patients are transplanted for other indications than the end-stage liver disease and without coagulopathy allowing insertion of an epidural catheter. Methods. This study is a retrospective observational single-center study of all adult patients undergoing first-time liver transplantation at Oslo University Hospital between January 1, 2008, and December 31, 2017. Data regarding patient characteristics were obtained from the Nordic liver transplant registry, medical records, and pain registration forms. Patients without coagulopathy (international normalized ratio <1.5 and platelets >100 × 109/L) were eligible for TEA. Results. Out of 685 first-time liver transplantations in a 10-year period, 327 received TEA, and 358 did not. The median Model of End-stage Liver Disease score was lower in the TEA group than in the non-TEA-group (9 versus 17, P < 0.001), and fewer patients were hospitalized preoperatively (16 versus 127, P < 0.001). The median international normalized ratio (1.1 versus 1.6, P < 0.001) and platelet count (190 versus 78, P < 0.001) were different between the TEA and non-TEA groups. There were no serious complications related to insertion or removal of the TEA catheters. Patients in the TEA group had less pain with a mean numeric rating scale at postoperative days 0–5 of 1.4 versus 1.8 (P = 0.008). Nearly 50% of the patients were prescribed opioids when discharged from hospital (non-TEA 154 versus TEA 158, P = 0.23), and there was no difference after 1 year (P = 0.718). Conclusions. Our report revealed very good pain control with both TEA and the non-TEA modality. TEA was without any serious complications like epidural hematoma or infection/abscess in selected liver transplant recipients without severe coagulopathy. Opioid prescription at hospital discharge and by 1-year follow-up did not differ between the groups.

• Lanari, Jacopo; Dueland, Svein & Line, Pål Dag (2020). Liver Transplantation for Colorectal Liver Metastasis. Current Transplantation Reports. 7(4), p. 311–316. doi: 10.1007/s40472-020-00298-8.
• Ignatavicius, Povilas; Oberkofler, Christian; Chapman, William; Dematteo, Ronald P.; Clary, Bryan & D'Angelica, Michael [Show all 47 contributors for this article] (2020). Choices of Therapeutic Strategies for Colorectal Liver Metastases Among Expert Liver Surgeons A Throw of the Dice? Annals of Surgery. ISSN 0003-4932. doi: 10.1097/SLA.0000000000004331.
• Line, Pål Dag (2020). Frontiers in liver transplantation. British Journal of Surgery. ISSN 0007-1323. 107(7), p. 790–792. doi: 10.1002/bjs.11714. Full text in Research Archive
• Bjerre, Anna Kristina; Mjøen, Geir; Line, Pål Dag; Naper, Christian; Reisæter, Anna Varberg & Åsberg, Anders (2020). Five decades with grandparent donors: The Norwegian strategy and experience. Pediatric Transplantation. ISSN 1397-3142. 24(6). doi: 10.1111/petr.13751. Full text in Research Archive
• Smedman, Tor Magnus; Line, Pål Dag; Hagness, Morten; Syversveen, Trygve; Grut, Harald & Dueland, Svein (2020). Liver transplantation for unresectable colorectal liver metastases in patients and donors with extended criteria (SECA-II arm D study). BJS Open. ISSN 2474-9842. 4(3), p. 467–477. doi: 10.1002/bjs5.50278. Full text in Research Archive
• Labori, Knut Jørgen; Kleive, Dyre; Khan, Ammar; Farnes, Ingvild; Fosby, Bjarte & Line, Pål Dag (2020). Graft type for superior mesenteric and portal vein reconstruction in pancreatic surgery – A systematic review. HPB. ISSN 1365-182X. p. 1–12. doi: 10.1016/j.hpb.2020.11.008. Full text in Research Archive
• Khan, Ammar; Kleive, Dyre; Aandahl, Einar Martin; Fosby, Bjarte; Line, Pål Dag & Dorenberg, Eric Jürgen [Show all 8 contributors for this article] (2020). Portal vein stent placement after hepatobiliary and pancreatic surgery. Langenbeck's Archives of Surgery. ISSN 1435-2443. 405, p. 657–664. doi: 10.1007/s00423-020-01917-9. Full text in Research Archive
• Shi, Jihua; Yan, X.; Zhang, S.J. & Line, Pål Dag (2020). Simulated model of RAPID concept: highlighting innate inflammation and liver regeneration. BJS Open. ISSN 2474-9842. 4(5), p. 893–903. doi: 10.1002/bjs5.50322. Full text in Research Archive
• Hibi, Taizo; Rela, Mohamed; Eason, James D.; Line, Pål Dag; Fung, John & Sakamoto, Seisuke [Show all 10 contributors for this article] (2020). Liver Transplantation for Colorectal and Neuroendocrine Liver Metastases and Hepatoblastoma. Working Group Report from the ILTS Transplant Oncology Consensus Conference. Transplantation. ISSN 0041-1337. p. 1131–1135. doi: 10.1097/TP.0000000000003118. Full text in Research Archive
• Dueland, Svein; Syversveen, Trygve; Solheim, Jon Magnus Aarstrand; Solberg, Steinar; Grut, Harald & Bjørnbeth, Bjørn Atle [Show all 8 contributors for this article] (2020). Survival following liver transplantation for patients with nonresectable liver-only colorectal metastases. Annals of Surgery. ISSN 0003-4932. 271(2), p. 212–218. doi: 10.1097/SLA.0000000000003404.
• Line, Pål Dag & Dueland, Svein (2020). Liver transplantation for secondary liver tumours: The difficult balance between survival and recurrence. Journal of Hepatology. ISSN 0168-8278. p. 1–6. doi: 10.1016/j.jhep.2020.08.015. Full text in Research Archive
• Golse, Nicolas; Joly, Florian; Nicolas, Quentin; Vibert, Eric; Line, Pål Dag & Clementel, Irene Vignon (2020). Partial orthotopic liver transplantation in combination with two-stage hepatectomy: A proof-of-concept explained by mathematical modeling. Clinical Biomechanics. ISSN 0268-0033. 73, p. 195–200. doi: 10.1016/j.clinbiomech.2020.01.020.
• Søreide, Kjetil; Hallet, Julie; Matthews, Jeffrey B.; Schnitzbauer, Andreas Anton; Line, Pål Dag & Lai, Paul B.S. [Show all 15 contributors for this article] (2020). Immediate and long-term impact of the COVID-19 pandemic on delivery of surgical services. British Journal of Surgery. ISSN 0007-1323. doi: 10.1002/bjs.11670. Full text in Research Archive
• Adam, René; Karam, Vincent; Cailliez, Valérie; Trunečka, Pavel; Samuel, Didier & Tisone, Giuseppe [Show all 48 contributors for this article] (2019). Improved survival in liver transplant patients receiving prolonged-release tacrolimus-based immunosuppression in the European Liver Transplant Registry (ELTR): An extension study. Transplantation. ISSN 0041-1337. 103(9), p. 1844–1862. doi: 10.1097/TP.0000000000002700.
• Dueland, Svein; Grut, Harald; Syversveen, Trygve; Hagness, Morten & Line, Pål Dag (2019). Selection criteria related to long-term survival following liver transplantation for colorectal liver metastasis. American Journal of Transplantation. ISSN 1600-6135. 20(2), p. 530–537. doi: 10.1002/bjs5.50116. Full text in Research Archive
• Shi, Jihua & Line, Pål Dag (2019). Hallmarks of postoperative liver regeneration: An updated insight on the regulatory mechanisms. Journal of Gastroenterology and Hepatology. ISSN 0815-9319. p. 1–7. doi: 10.1111/jgh.14944. Full text in Research Archive
• Smedman, Tor Magnus; Guren, Tormod Kyrre; Line, Pål Dag & Dueland, Svein (2019). Transplant oncology: assessment of response and tolerance to systemic chemotherapy for metastatic colorectal cancer after liver transplantation - a retrospective study. Transplant International. ISSN 0934-0874. 32(11), p. 1144–1150. doi: 10.1111/tri.13471. Full text in Research Archive
• Thorsen, Trygve; Solheim, Jon Magnus Aarstrand; Labori, Knut Jørgen; Line, Pål Dag & Aandahl, Einar Martin (2019). Liver transplantation as a lifesaving procedure for posthepatectomy liver failure and iatrogenic liver injuries. Langenbeck's Archives of Surgery. ISSN 1435-2443. doi: 10.1007/s00423-019-01780-3. Full text in Research Archive
• Hagness, Morten; Foss, Stein; SØRENSEN, DAG WENDELBO; Syversen, Torgunn Bø; Bakkan, Per Arne & Dahl, Thorleif [Show all 8 contributors for this article] (2019). Liver Transplant After Normothermic Regional Perfusion From Controlled Donors After Circulatory Death: The Norwegian Experience. Transplantation Proceedings. ISSN 0041-1345. 51(2), p. 475–478. doi: 10.1016/j.transproceed.2019.01.066. Full text in Research Archive
• Shi, Jihua; Guo, Wen-Zhi; Jin, Yang; Zhang, Hua-Peng; Pang, Chun & Li, Jie [Show all 8 contributors for this article] (2019). Recognition of HER2 expression in hepatocellular carcinoma and its significance in postoperative tumor recurrence. Cancer Medicine. ISSN 2045-7634. 8(3), p. 1269–1278. doi: 10.1002/cam4.2006. Full text in Research Archive
• Mauseth, Brynjar; Camilio, Ketil Andre; Shi, Jihua; Hammarström, Clara Louise; Rekdal, Øystein & Sveinbjørnsson, Baldur [Show all 7 contributors for this article] (2019). The Novel Oncolytic Compound LTX-401 Induces Antitumor Immune Responses in Experimental Hepatocellular Carcinoma. Molecular Therapy Oncolytics. ISSN 2372-7705. 14, p. 139–148. doi: 10.1016/j.omto.2019.05.002. Full text in Research Archive
• Kleive, Dyre; Labori, Knut Jørgen; Line, Pål Dag; Gladhaug, Ivar Prydz & Verbeke, Caroline Sophie (2019). Pancreatoduodenectomy with venous resection for ductal adenocarcinoma rarely achieves complete (R0) resection. HPB. ISSN 1365-182X. 22(1), p. 50–57. doi: 10.1016/j.hpb.2019.05.005. Full text in Research Archive
• Andres, Axel; Oldani, Graziano; Berney, Thierry; Compagnon, Philippe; Line, Pål Dag & Toso, Christian (2018). Transplantation for colorectal metastases: on the edge of a revolution. Translational gastroenterology and hepatology (TGH). ISSN 2415-1289. 3(9, September), p. 1–8. doi: 10.21037/tgh.2018.08.04. Full text in Research Archive
• Adam, René; Karam, Vincent; Cailliez, Valérie; O'Grady, John G.; Mirza, Darius Feroze & Cherqui, Daniel [Show all 44 contributors for this article] (2018). 2018 Annual Report of the European Liver Transplant Registry (ELTR) - 50-year evolution of liver transplantation. Transplant International. ISSN 0934-0874. 31(12), p. 1293–1317. doi: 10.1111/tri.13358.
• Baumann, Ulrich; Adam, René; Duvoux, Christophe; Mikolajczyk, Rafael; Karam, Vincent & D'Antiga, Lorenzo [Show all 22 contributors for this article] (2018). Survival of children after liver transplantation for hepatocellular carcinoma. Liver transplantation. ISSN 1527-6465. 24(2), p. 246–255. doi: 10.1002/lt.24994.
• Carling, Johan Ulrik; Røsok, Bård Ingvald; Line, Pål Dag & Dorenberg, Eric Jürgen (2018). ALBI and P-ALBI grade in Child-Pugh A patients treated with drug eluting embolic chemoembolization for hepatocellular carcinoma. Acta Radiologica. ISSN 0284-1851. p. 1–8. doi: 10.1177/0284185118799519.
• Holmer, Magnus; Melum, Espen; Isoniemi, Helena; Ericzon, Bo-Göran; Castedal, Maria & Nordin, Arno [Show all 12 contributors for this article] (2018). Nonalcoholic fatty liver disease is an increasing indication for liver transplantation in the Nordic countries. Liver international (Print). ISSN 1478-3223. 38(11), p. 2082–2090. doi: 10.1111/liv.13751.
• Kleive, Dyre; Sahakyan, Mushegh; Søreide, Kjetil; Brudvik, Kristoffer Watten; Line, Pål Dag & Gladhaug, Ivar Prydz [Show all 7 contributors for this article] (2018). Risk for hemorrhage after pancreatoduodenectomy with venous resection. Langenbeck's Archives of Surgery. ISSN 1435-2443. p. 1–9. doi: 10.1007/s00423-018-1721-y.
• Åberg, Fredrik; Isoniemi, Helena; Pukkala, Eero; Jalanko, Hannu; Rasmussen, Allan & Storm, Hans H. [Show all 17 contributors for this article] (2018). Cancer After Liver Transplantation in Children and Young Adults: A Population-Based Study From 4 Nordic Countries. Liver transplantation. ISSN 1527-6465. 24(9), p. 1252–1259. doi: 10.1002/lt.25305. Full text in Research Archive
• Thorgersen, Ebbe Billmann; Melum, Espen; Folseraas, Trine; Larsen, Stein Gunnar & Line, Pål Dag (2018). Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for pseudomyxoma peritonei in a liver-transplanted patient: A case report. World Journal of Surgical Oncology (WJSO). ISSN 1477-7819. 16:180, p. 1–5. doi: 10.1186/s12957-018-1482-7. Full text in Research Archive
• Berntsen, Natalie Lie; Fosby, Bjarte; Tan, Corey; Reims, Henrik Mikael; Øgaard, Jonas & Jiang, Xiaojun [Show all 12 contributors for this article] (2018). Natural killer T cells mediate inflammation in the bile ducts. Mucosal Immunology. ISSN 1933-0219. p. 1–9. doi: 10.1038/s41385-018-0066-8.
• Bjørnelv, Gudrun Maria Waaler; Dueland, Svein; Line, Pål Dag; Joranger, Pål; Fretland, Åsmund Avdem & Edwin, Bjørn [Show all 8 contributors for this article] (2018). Cost-effectiveness of liver transplantation in patients with colorectal metastases confined to the liver. British Journal of Surgery. ISSN 0007-1323. doi: 10.1002/bjs.10962.
• Dueland, Svein; Line, Pål Dag; Hagness, Morten; Foss, Aksel & Andersen, Marit Helen (2018). Long‐term quality of life after liver transplantation for non‐resectable colorectal metastases confined to the liver. JBJS Open Access. ISSN 2472-7245. 3(2), p. 180–185. doi: 10.1002/bjs5.50116. Full text in Research Archive
• Foss, Stein; Nordheim, Espen; SØRENSEN, DAG WENDELBO; Syversen, Torgunn Bø; Midtvedt, Karsten & Åsberg, Anders [Show all 12 contributors for this article] (2018). First Scandinavian Protocol for Controlled Donation After Circulatory Death Using Normothermic Regional Perfusion. Transplantation direct. ISSN 2373-8731. 4(7). doi: 10.1097/TXD.0000000000000802. Full text in Research Archive
• Grut, Harald; Rootwelt-Revheim, Mona-Elisabeth; Line, Pål Dag & Dueland, Svein (2018). Importance of 18F-FDG PET/CT to select patients with nonresectable colorectal liver metastases for liver transplantation. Nuclear medicine communications. ISSN 0143-3636. 39(7), p. 621–627. doi: 10.1097/MNM.0000000000000843.
• Bjørnland, Kristin; Hinna, Maren Tveit; Aksnes, Gunnar; Stensrud, Kjetil Juul; Ertresvåg, Kjetil & Østensen, Inger Anniken Bjørnstad [Show all 12 contributors for this article] (2018). Outcome for biliary atresia patients treated at a low-volume centre. Scandinavian Journal of Gastroenterology. ISSN 0036-5521. 53(4), p. 471–474. doi: 10.1080/00365521.2018.1439097. Full text in Research Archive
• Dueland, Svein; Foss, Aksel; Solheim, Jon Magnus Aarstrand; Hagness, Morten & Line, Pål Dag (2018). Survival following liver transplantation for liver-only colorectal metastases compared with hepatocellular carcinoma. British Journal of Surgery. ISSN 0007-1323. 105(6), p. 736–742. doi: 10.1002/bjs.10769.
• Kleive, Dyre; Sahakyan, Mushegh; Khan, Ammar; Fosby, Bjarte; Line, Pål Dag & Labori, Knut Jørgen (2018). Incidence and management of arterial injuries during pancreatectomy. Langenbeck's Archives of Surgery. ISSN 1435-2443. 403(3), p. 341–348. doi: 10.1007/s00423-018-1666-1.

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• Dueland, Svein; Syversveen, Trygve & Line, Pål Dag (2024). In Reply. JAMA Surgery. ISSN 2168-6254. doi: 10.1001/jamasurg.2023.5800.
• Wehrle, Chase J.; Fujiki, Masato; Schlegel, Andrea; Whitsett Linganna, Maureen; Pita, Alejandro & Kim, Jae-Keun [Show all 15 contributors for this article] (2023). Update to ‘A Contemporary Systematic Review on Liver Transplantation for Unresectable Liver Metastasis of Colorectal Cancer’. Annals of Surgical Oncology. ISSN 1068-9265. doi: 10.1245/s10434-023-14611-z.
• Hernandez-Alejandro, Roberto; Chávez-Villa, Mariana; Line, Pål Dag & Sapisochin, Gonzalo (2023). Festina lente—to advance we need to make haste slowly. Living donor liver transplant for colorectal cancer liver metastases. American Journal of Transplantation. ISSN 1600-6135. doi: 10.1016/j.ajt.2023.09.015.
• Siriwardena, Ajith K.; Serrablo, Alejandro; Fretland, Åsmund Avdem; Wigmore, Stephen J.; Ramia-Angel, Jose M. & Malik, Hassan Z. [Show all 95 contributors for this article] (2023). The multi-societal European consensus on the terminology, diagnosis and management of patients with synchronous colorectal cancer and liver metastases: an E-AHPBA consensus in partnership with ESSO, ESCP, ESGAR, and CIRSE. HPB. ISSN 1365-182X. 25(9), p. 985–999. doi: 10.1016/j.hpb.2023.05.360.
• Skauby, Morten Heier; Heldal, Kristian; Line, Pål Dag; SØRENSEN, DAG WENDELBO; Fiane, Arnt Eltvedt & Hagness, Morten (2023). Lengre ventelister for organtransplantasjon. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 143(9). doi: 10.4045/tidsskr.22.0777.
• Menon, Krishna; Vijayashanker, Aarathi; Murphy, Jamie; Line, Pål Dag; Isaac, John & Adair, Anya [Show all 19 contributors for this article] (2023). Liver transplantation for isolated unresectable colorectal liver metastases - Protocol for a service evaluation in the United Kingdom - UKCoMET study. HPB. ISSN 1365-182X. 25(6), p. 684–692. doi: 10.1016/j.hpb.2023.02.011.
• Dueland, Svein; Yaqub, Sheraz & Line, Pål Dag (2022). No Strong Evidence on Liver Transplant for Colorectal Cancer Liver Metastasis Over Portal Vein Embolization Associated With Liver Resection-Reply. JAMA Surgery. ISSN 2168-6254. doi: 10.1001/jamasurg.2021.5127.
• Line, Pål Dag (2022). Selection criteria in liver transplantation for hepatocellular carcinoma: an ongoing evolution. BJS Open. ISSN 2474-9842. 6(1). doi: 10.1093/bjsopen/zrac024.
• Line, Pål Dag; Nadalin, Silvio & Balci, Deniz (2021). Auxiliary two-staged partial resection liver transplantation. BMC Surgery. ISSN 1471-2482. 21(1). doi: 10.1186/s12893-021-01265-5.
• Rammohan, Ashwin; Reddy, Mettu S.; Line, Pål Dag & Rela, Mohamed (2021). Heterotopic liver transplantation: Temporary solution, permanent problem? American Journal of Transplantation. ISSN 1600-6135. 21(2), p. 903–904. doi: 10.1111/ajt.16271.
• Dueland, Svein & Line, Pål Dag (2021). Response to the Comment on "Survival Following Liver Transplantation for Patients With Nonresectable Liver-only Colorectal Metastases". Annals of Surgery. ISSN 0003-4932. 274(6), p. e721–e722. doi: 10.1097/SLA.0000000000003953.
• Line, Pål-Dag (2021). Contemporary outcome of liver transplantation for bilobar multiple colorectal liver metastasis. Surgery. ISSN 0039-6060. doi: 10.14701/ahbps.LV-SY-3-4.
• Dueland, Svein; Yaqub, Sheraz & Line, Pål Dag (2021). No Strong Evidence on Liver Transplant for Colorectal Cancer Liver Metastasis over Portal Vein Embolization Associated with Liver Resection-Reply. JAMA Surgery. ISSN 2168-6254. doi: 10.1001/jamasurg.2021.5127.
• Golse, Nicolas; Joly, Florian; Nicolas, Quentin; Vibert, Eric; Line, Pål Dag & Vignon-Clementel, Irene (2020). Corrigendum: “Partial orthotopic liver transplantation in combination with two-stage hepatectomy: A proof-of-concept explained by mathematical modeling” (Clinical Biomechanics (2020) 73 (195–200), (S0268003320300462), (10.1016/j.clinbiomech.2020.01.020)). Clinical Biomechanics. ISSN 0268-0033. 77. doi: 10.1016/j.clinbiomech.2020.105047.
• Line, Pål Dag; Ruffolo, Luis I.; Toso, Christian; Dueland, Svein; Nadalin, Silvio & Hernandez-Alejandro, Roberto (2020). Liver transplantation for colorectal liver metastases: What do we need to know? International Journal of Surgery (IJS). ISSN 1743-9191. 82, p. 87–92. doi: 10.1016/j.ijsu.2020.03.079.
• Haugaa, Håkon; Line, Pål Dag & Tønnessen, Tor Inge (2020). An Increased Lactate-to-pyruvate Ratio Is Not a Stand-alone Marker of Ischemia. Transplantation direct. ISSN 2373-8731. doi: 10.1097/TXD.0000000000000991.
• Nadalin, Silvio; Settmacher, Utz; Rauchfuß, Falk; Balci, Deniz; Königsrainer, Alfred & Line, Pål Dag (2020). RAPID procedure for colorectal cancer liver metastasis. International Journal of Surgery (IJS). ISSN 1743-9191. 82, p. 93–96. doi: 10.1016/j.ijsu.2020.03.078.
• Bjørlykke, Kristin Hammersbøen; Eftang, Lars Lohne; Grzyb, Krzysztof; Line, Pål Dag; Lassen, Kristoffer & Jahnsen, Jørgen (2020). A man in his fifties with abdominal pain, itching and weight loss. Tidsskrift for Den norske legeforening. ISSN 0029-2001. doi: 10.4045/tidsskr.19.0390.
• Fernandes, Eduardo de Souza M.; Line, Pål Dag; de MELLO, Felipe Pedreira; Andrade, Ronaldo Oliveira; Girão, Camila Liberato & Pimentel, Leandro Savattone [Show all 11 contributors for this article] (2019). Living donor liver transplant for colorectal liver metastasis: The first case in latin America. Arquivos Brasileiros de Cirurgia Digestiva (ABCD). ISSN 0102-6720. 32(4). doi: 10.1590/0102-672020180001e1468.
• Dueland, Svein & Line, Pål Dag (2019). Response to "letter to the Editor" from Drs A. Gorgen and G. Sapisochin and Drs D. Azoulay and C. Lim. Annals of Surgery. ISSN 0003-4932. 271(5). doi: 10.1097/SLA.0000000000003604.
• Smedman, Tor Magnus; Line, Pål Dag; Guren, Tormod Kyrre & Dueland, Svein (2018). Graft rejection after immune checkpoint inhibitor therapy in solid organ transplant recipients. Acta Oncologica. ISSN 0284-186X. 57(10), p. 1414–1418. doi: 10.1080/0284186X.2018.1479069.

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