Ragnhild A Lothe

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Phone +47-22934415
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Visiting address Ullernchausseen 70 None 0372 OSLO
Postal address Postboks 4950 Nydalen 0424 OSLO

Publications

  • Danielsen, Håvard Emil; Hveem, Tarjei Sveinsgjerd; Domingo, Enric; Pradhan, Manohar; Kleppe, Andreas; Syvertsen, Rolf Anders; Kostolomov, Ilya; Nesheim, John Arne; Askautrud, Hanne Arenberg; Nesbakken, Arild; Lothe, Ragnhild A; Svindland, Aud; Shephard, Neil; Novelli, Marco; Johnstone, Elaine; Tomlinson, I; Kerr, Rachel & Kerr, David (2018). Prognostic markers for colorectal cancer: Estimating ploidy and stroma. Annals of Oncology.  ISSN 0923-7534.  29(3), s 616- 623 . doi: 10.1093/annonc/mdx794
  • Høland, Maren; Kolberg, Matthias; Danielsen, Stine Aske; Bjerkehagen, Bodil; Eilertsen, Ina Andrassy; Hektoen, Merete; Mandahl, Nils; van den Berg, Eva; Smeland, Sigbjørn; Mertens, Fredrik; Hall, Kirsten Sundby; Picci, Piero; Sveen, Anita & Lothe, Ragnhild A (2018). Inferior survival for patients with malignant peripheral nerve sheath tumors defined by aberrant TP53. Modern Pathology.  ISSN 0893-3952.  s 1- 14 . doi: 10.1038/s41379-018-0074-y
  • Løvf, Marthe; Zhao, Sen; Axcrona, Ulrika; Johannessen, Bjarne; Bakken, Anne Cathrine; Carm, Kristina Totland; Hoff, Andreas Midbøe; Myklebost, Ola; Meza, Leonardo Zepeda; Lie, Kathrine; Axcrona, Karol; Lothe, Ragnhild A & Skotheim, Rolf I. (2018). Multifocal primary prostate cancer exhibits high degree of genomic heterogeneity. European Urology.  ISSN 0302-2838.  s 1- 8 . doi: 10.1016/j.eururo.2018.08.009
  • Løvf, Marthe; Zhao, Sen; Axcrona, Ulrika; Johannessen, Bjarne; Bakken, Anne Cathrine; Carm, Kristina Totland; Hoff, Andreas Midbøe; Myklebost, Ola; Meza-Zepeda, Leonardo A; Lie, A. Kathrine; Axcrona, Karol; Lothe, Ragnhild A & Skotheim, Rolf I. (2018). High degree of genomic heterogeneity in multifocal primary prostate cancer. European Urology.  ISSN 0302-2838.
  • Oltedal, Satu; Kørner, Hartwig; Aasprong, Ole Gunnar; Hussain, Israr; Tjensvoll, Kjersti; Smaaland, Rune; Søreide, Jon Arne; Søreide, Kjetil; Lothe, Ragnhild A; Heikkilä, Reino; Gilje, Bjørnar & Nordgård, Oddmund (2018). The Prognostic Relevance of Sentinel Lymph Node Metastases Assessed by PHGR1 mRNA Quantification in Stage I to III Colon Cancer. Translational Oncology.  ISSN 1936-5233.  11(2), s 436- 443 . doi: 10.1016/j.tranon.2018.01.015
  • Pharo, Heidi Dietrichson; Andresen, Kim; Berg, Kaja Christine Graue; Lothe, Ragnhild A; Jeanmougin, Marine & Lind, Guro Elisabeth (2018). A robust internal control for high-precision DNA methylation analyses by droplet digital PCR. Clinical Epigenetics.  ISSN 1868-7075.  10(24) . doi: 10.1186/s13148-018-0456-5
  • Smeby, Jørgen; Sveen, Anita; Merok, Marianne Aarstad; Danielsen, Stine Aske; Eilertsen, Ina Andrassy; Guren, Marianne; Dienstmann, Rodrigo; Nesbakken, Arild & Lothe, Ragnhild A (2018). CMS-dependent prognostic impact of KRAS and BRAFV600E mutations in primary colorectal cancer. Annals of Oncology.  ISSN 0923-7534.  29(5), s 1227- 1234 . doi: 10.1093/annonc/mdy085
  • Vedeld, Hege Marie; Nesbakken, Arild; Lothe, Ragnhild A & Lind, Guro Elisabeth (2018). Re-assessing ZNF331 as a DNA methylation biomarker for colorectal cancer. Clinical Epigenetics.  ISSN 1868-7075.  10(1) . doi: 10.1186/s13148-018-0503-2
  • Berg, Kaja Christine Graue; Eide, Peter Andreas Wold; Eilertsen, Ina Andrassy; Johannessen, Bjarne; Bruun, Jarle; Danielsen, Stine Aske; Bjørnslett, Merete Pauline; Meza, Leonardo Zepeda; Eknæs, Mette; Lind, Guro Elisabeth; Myklebost, Ola; Skotheim, Rolf I.; Sveen, Anita & Lothe, Ragnhild A (2017). Multi-omics of 34 colorectal cancer cell lines - a resource for biomedical studies. Molecular Cancer.  ISSN 1476-4598.  16:116, s 1- 16 . doi: 10.1186/s12943-017-0691-y
  • Dienstmann, Rodrigo; Mason, M; Sinicrope, FA; Phipps, Alison; Tejpar, S.; Nesbakken, Arild; Danielsen, Stine Aske; Sveen, Anita; Buchanan, Daniel D.; Lothe, Ragnhild A; Delorenzi, M; Newcomb, PA; Sargent, DJ & Guinney, Justin (2017). Prediction of overall survival in stage II and III colon cancer beyond TNM system: a retrospective, pooled biomarker study.. Annals of Oncology.  ISSN 0923-7534.  28(5), s 1023- 1031 . doi: 10.1093/annonc/mdx052 Full text in Research Archive.
  • Eide, Peter Andreas Wold; Bruun, Jarle; Lothe, Ragnhild A & Sveen, Anita (2017). CMScaller: An R package for consensus molecular subtyping of colorectal cancer pre-clinical models. Scientific Reports.  ISSN 2045-2322.  7(1) . doi: 10.1038/s41598-017-16747-x Show summary
  • Kolberg, Matthias; Bruun, Jarle; Murumagi, Astrid; Mpindi, John P.; Bergsland, Christian Holst; Høland, Maren; Eilertsen, Ina Andrassy; Danielsen, Stine Aske; Kallioniemi, Olli & Lothe, Ragnhild A (2017). Drug sensitivity and resistance testing identifies PLK1 inhibitors and gemcitabine as potent drugs for malignant peripheral nerve sheath tumors. Molecular Oncology.  ISSN 1574-7891.  11(9), s 1156- 1171 . doi: 10.1002/1878-0261.12086
  • Landskron, Johannes; Kraggerud, Sigrid M.; Wik, Elisabeth; Dørum, Anne; Bjørnslett, Merete Pauline; Melum, Espen; Helland, Øystein; Bjørge, Line; Lothe, Ragnhild A; Salvesen, Helga & Tasken, Kjetil (2017). C77G in PTPRC (CD45) is no risk allele for ovarian cancer, but associated with less aggressive disease. PLoS ONE.  ISSN 1932-6203.  12:e0182030(7), s 1- 12 . doi: 10.1371/journal.pone.0182030 Full text in Research Archive.
  • Lind, Guro Elisabeth; Guriby, Marianne; Ahlquist, Terje Cruickshank; Hussain, Israr; Jeanmougin, Marine; Søreide, Kjetil; Kørner, Hartwig; Lothe, Ragnhild A & Nordgård, Oddmund (2017). Prognostic relevance of an epigenetic biomarker panel in sentinel lymph nodes from colon cancer patients. Clinical Epigenetics.  ISSN 1868-7075.  9:97, s 1- 8 . doi: 10.1186/s13148-017-0397-4 Full text in Research Archive.
  • Ramalho-Carvalho, João; Martins, João Barbosa; Cekaite, Lina; Sveen, Anita; Torres-Ferreira, Jorge; Graça, Inês; Costa-Pinheiro, Pedro; Eilertsen, Ina Andrassy; Antunes, Luis; Oliveira, Jorge; Lothe, Ragnhild A; Henrique, Rui & Jeronimo, Carmen (2017). Epigenetic disruption of miR-130a promotes prostate cancer by targeting SEC23B and DEPDC1. Cancer Letters.  ISSN 0304-3835.  385, s 150- 159 . doi: 10.1016/j.canlet.2016.10.028
  • Sveen, Anita; Bruun, Jarle; Eide, Peter Andreas Wold; Eilertsen, Ina Andrassy; Ramirez, Lorena; Murumagi, Astrid; Arjama, Mariliina; Danielsen, Stine Aske; Kryeziu, Kushtrim; Elez, Elena; Tabernero, Josep; Guinney, Justin; Palmer, Hector G.; Nesbakken, Arild; Kallioniemi, Olli; Dienstmann, Rodrigo & Lothe, Ragnhild A (2017). Colorectal cancer consensus molecular subtypes translated to preclinical models uncover potentially targetable cancer cell dependencies. Clinical Cancer Research.  ISSN 1078-0432.  24(4), s 794- 806 . doi: 10.1158/1078-0432.CCR-17-1234
  • Sveen, Anita; Bruun, Jarle; Eide, Peter W.; Eilertsen, Ina A.; Ramirez, Lorena; Murumagi, Astrid; Arjama, Mariliina; Danielsen, Stine Aske; Kryeziu, Kushtrim; Elez, Elena; Tabernero, Josep; Guinney, Justin; Palmer, Hector G.; Nesbakken, Arild; Kallioniemi, Olli; Dienstmann, Rodrigo & Lothe, Ragnhild A (2017). Colorectal cancer consensus molecular subtypes define selective activity of HSP90 inhibitors in preclinical models. Cancer Reports and Reviews.  ISSN 2513-9290. . doi: 10.1158/1078-0432.CCR-17-1234
  • Sveen, Anita; Johannessen, Bjarne; Tengs, Torstein; Danielsen, Stine Aske; Eilertsen, Ina Andrassy; Lind, Guro Elisabeth; Berg, Kaja Christine Graue; Leithe, Edward; Meza, Leonardo Zepeda; Domingo, Enric; Myklebost, Ola; Kerr, David; Tomlinson, Ian; Nesbakken, Arild; Skotheim, Rolf I. & Lothe, Ragnhild A (2017). Multilevel genomics of colorectal cancers with microsatellite instability – clinical impact of JAK1 mutations and consensus molecular subtype 1. Genome Medicine.  ISSN 1756-994X.  9(1) . doi: 10.1186/s13073-017-0434-0
  • Totland, Max; Bergsland, Christian Holst; Fykerud, Tone Aase; Knudsen, Lars Mørland; Rasmussen, Nikoline L.; Eide, Peter Andreas Wold; Yohannes, Zeremariam; Sørensen, Vigdis; Brech, Andreas; Lothe, Ragnhild A & Leithe, Edward (2017). The E3 ubiquitin ligase NEDD4 induces endocytosis and lysosomal sorting of connexin 43 to promote loss of gap junctions. Journal of Cell Science.  ISSN 0021-9533.  130(17), s 2867- 2882 . doi: 10.1242/jcs.202408
  • Vedeld, Hege Marie; Merok, Marianne Aarstad; Jeanmougin, Marine; Danielsen, Stine Aske; Honne, Hilde; Presthus, Gro; Svindland, Aud; Sjo, Ole Helmer; Hektoen, Merete; Eknæs, Mette; Nesbakken, Arild; Lothe, Ragnhild A & Lind, Guro Elisabeth (2017). CpG island methylator phenotype identifies high risk patients among microsatellite stable BRAF mutated colorectal cancers. International Journal of Cancer.  ISSN 0020-7136.  141(5), s 967- 976 . doi: 10.1002/ijc.30796
  • Domingo, Enric; Freeman-Mills, Luke; Rayner, Emily; Glaire, Mark; Briggs, Sarah; Vermeulen, Louis; Fessler, Evelyn; Medema, Jan Paul; Boot, Arnoud; Morreau, Hans; van Wezel, Tom; Liefers, Gerrit-Jan; Lothe, Ragnhild A; Danielsen, Stine Aske; Sveen, Anita; Nesbakken, Arild; Zlobec, Inti; Lugli, Alessandro; Kölzer, Viktor H.; Berger, Martin D.; Castellví-Bel, Sergi; Muñoz, Jenifer; de Bruyn, Marco; Nijman, Hans W.; Novelli, Marco; Lawson, Kay; Oukrif, Dahmane; Frangou, Eleni; Dutton, Peter; Tejpar, Sabine; Delorenzi, Mauro; Kerr, Rachel; Kerr, David; Tomlinson, Ian & Church, David N. (2016). Somatic POLE proofreading domain mutation, immune response, and prognosis in colorectal cancer: a retrospective, pooled biomarker study. The Lancet Gastroenterology and Hepatology.  ISSN 2468-1253.  1(3), s 207- 216 . doi: 10.1016/S2468-1253(16)30014-0
  • Fykerud, Tone Aase; Knudsen, Lars Mørland; Totland, Max; Sørensen, Vigdis; Dahal-Koirala, Shiva; Lothe, Ragnhild A; Brech, Andreas & Leithe, Edward (2016). Mitotic cells form actin-based bridges with adjacent cells to provide intercellular communication during rounding. Cell Cycle.  ISSN 1538-4101.  15(21), s 2943- 2957 . doi: 10.1080/15384101.2016.1231280 Full text in Research Archive.
  • Hoff, Andreas Midbøe; Alagaratnam, Sharmini; Zhao, Sen; Bruun, Jarle; Andrews, PW; Lothe, Ragnhild A & Skotheim, Rolf Inge (2016). Identification of novel fusion genes in testicular germ cell tumors. Cancer Research.  ISSN 0008-5472.  76(1), s 108- 116 . doi: 10.1158/0008-5472.CAN-15-1790
  • Lorenz, Susanne; Barøy, Tale; Sun, Jinchang; Nome, Torfinn; Vodak, Daniel; Bryne, Jan Christian; Håkelien, Anne-Mari; Fernandez-Cuesta, Lynnette; Möhlendick, B; Rieder, H; Szuhai, K; Zaikova, Olga; Ahlquist, Terje Cruickshank; Thomassen, Gard O Sundby; Skotheim, Rolf Inge; Lothe, Ragnhild A; Tarpey, P; Campbell, P.; Flanagan, A; Myklebost, Ola & Meza, Leonardo Zepeda (2016). Unscrambling the genomic chaos of osteosarcoma reveals extensive transcript fusion, recurrent rearrangements and frequent novel TP53 aberrations. OncoTarget.  ISSN 1949-2553.  7(5), s 5273- 5288 . doi: 10.18632/oncotarget.6567 Show summary
  • Sveen, Anita; Kilpinen, Sami; Ruusulehto, Anja; Lothe, Ragnhild A & Skotheim, Rolf Inge (2016). Aberrant RNA splicing in cancer; Expression changes and driver mutations of splicing factor genes. Oncogene.  ISSN 0950-9232.  35(19), s 2413- 2427 . doi: 10.1038/onc.2015.318
  • Sveen, Anita; Løes, Inger Marie; Alagaratnam, Sharmini; Nilsen, Gro; Høland, Maren; Lingjærde, Ole Christian; Sorbye, Halfdan; Berg, Kaja Christine Graue; Horn, Arild; Angelsen, Jon-Helge; Knappskog, Stian; Lønning, Per Eystein & Lothe, Ragnhild A (2016). Intra-patient inter-metastatic genetic heterogeneity in colorectal cancer as a key determinant of survival after curative liver resection. PLoS Genetics.  ISSN 1553-7390.  12:e1006225(7) . doi: 10.1371/journal.pgen.1006225
  • Andresen, Kim; Boberg, Kirsten Muri; Vedeld, Hege Marie; Honne, Hilde; Jebsen, Peter Wilhelm; Hektoen, Merete; Wadsworth, Christopher A; Clausen, Ole Petter Fraas; Lundin, Knut E A; Paulsen, Vemund; Foss, Aksel; Mathisen, Øystein; Aabakken, Lars; Schrumpf, Erik; Lothe, Ragnhild A & Lind, Guro Elisabeth (2015). Four DNA methylation biomarkers in biliary brush samples accurately identify the presence of cholangiocarcinoma. Hepatology.  ISSN 0270-9139.  61(5), s 1651- 1659 . doi: 10.1002/hep.27707
  • Brabrand, Sigmund; Johannessen, Bjarne; Axcrona, Ulrika; Kraggerud, Sigrid M.; Berg, Kaja Christine Graue; Bakken, Anne Cathrine; Bruun, Jarle; Fosså, Sophie Dorothea; Lothe, Ragnhild A; Lehne, Gustav & Skotheim, Rolf Inge (2015). Exome sequencing of bilateral testicular germ cell tumors suggests independent development lineages. Neoplasia.  ISSN 1522-8002.  17(2), s 167- 174 . doi: 10.1016/j.neo.2014.12.005
  • Bruun, Jarle; Kolberg, Matthias; Ahlquist, Terje Cruickshank; Røyrvik, Ellen Christine; Nome, Torfinn; Leithe, Edward; Lind, Guro Elisabeth; Merok, Marianne Aarstad; Rognum, Torleiv Ole; Bjørkøy, Geir; Johansen, Terje; Lindblom, Annika; Sun, X-F.; Svindland, Aud; Liestøl, Knut; Nesbakken, Arild; Skotheim, Rolf Inge & Lothe, Ragnhild A (2015). Regulator of chromosome condensation 2 identifies high-risk patients within both major phenotypes of colorectal cancer. Clinical Cancer Research.  ISSN 1078-0432.  21(16), s 3759- 3770 . doi: 10.1158/1078-0432.CCR-14-3294
  • Cekaite, Lina; Eide, Peter Andreas Wold; Lind, Guro Elisabeth; Skotheim, Rolf I. & Lothe, Ragnhild A (2015). MicroRNAs as growth regulators, their function and biomarker status in colorectal cancer. OncoTarget.  ISSN 1949-2553.  7(6), s 6476- 6505 . doi: 10.18632/oncotarget.6390
  • Danielsen, Stine Aske; Eide, Peter Andreas Wold; Nesbakken, Arild; Guren, Tormod Kyrre; Leithe, Edward & Lothe, Ragnhild A (2015). Portrait of the PI3K/AKT pathway in colorectal cancer. Acta Biochimica et Biophysica Sinica.  ISSN 0582-9879.  1855(1), s 104- 121 . doi: 10.1016/j.bbcan.2014.09.008
  • Danielsen, Stine Aske; Lind, Guro Elisabeth; Kolberg, Matthias; Høland, Maren; Bjerkehagen, Bodil; Hall, Kirsten Sundby; Berg, eva van den; Mertens, Fredrik; Smeland, Sigbjørn; Picci, Piero & Lothe, Ragnhild A (2015). Methylated RASSF1A in malignant peripheral nerve sheath tumors identifies neurofibromatosis type 1 patients with inferior prognosis. Neuro-Oncology.  ISSN 1522-8517.  17(1), s 63- 69 . doi: 10.1093/neuonc/nou140
  • Hoff, Andreas Midbøe; Johannessen, Bjarne; Alagaratnam, Sharmini; Zhao, Sen; Nome, Torfinn; Løvf, Marthe; Bakken, Anne Cathrine; Hektoen, Merete; Sveen, Anita; Lothe, Ragnhild A & Skotheim, Rolf Inge (2015). Novel RNA variants in colorectal cancers. OncoTarget.  ISSN 1949-2553.  6(34), s 36587- 36602 . doi: 10.18632/oncotarget.5500
  • Kolberg, Matthias; Høland, Maren; Lind, Guro Elisabeth; Ågesen, Trude Holmeide; Skotheim, Rolf Inge; Hall, Kirsten Sundby; Mandahl, Nils; Smeland, Sigbjørn; Mertens, Fredrik; Davidson, Ben & Lothe, Ragnhild A (2015). Protein expression of BIRC5, TK1, and TOP2A in malignant peripheral nerve sheath tumours - A prognostic test after surgical resection. Molecular Oncology.  ISSN 1574-7891.  9(6), s 1129- 1139 . doi: 10.1016/j.molonc.2015.02.005
  • Kolberg, Matthias; Smeland, Sigbjørn & Lothe, Ragnhild A (2015). Adjuvant chemotherapy in malignant peripheral nerve sheath tumors. Chemotherapy: Open Access.  ISSN 2167-7700.  4(3), s 158 . doi: 10.4172/2167-7700.1000158
  • Mesquita, Diana; Barros-Silva, João D.; Santos, Joana; Skotheim, Rolf Inge; Lothe, Ragnhild A; Paulo, Paula & Teixeira, Manuel (2015). Specific and redundant activities of ETV1 and ETV4 in prostate cancer aggressiveness revealed by co-overexpression cellular contexts. OncoTarget.  ISSN 1949-2553.  6(7), s 5217- 5236 . doi: 10.18632/oncotarget.2847
  • Sirnes, Solveig; Lind, Guro Elisabeth; Bruun, Jarle; Fykerud, Tone Aase; Mesnil, Marc; Lothe, Ragnhild A; Rivedal, Edgar; Kolberg, Matthias & Leithe, Edward (2015). Connexins in colorectal cancer pathogenesis. International Journal of Cancer.  ISSN 0020-7136.  137(1), s 1- 11 . doi: 10.1002/ijc.28911
  • Almeida, Mafalda; Costa, Vera L; Costa, Natália R.; Ramalho-Carvalho, João; Baptista, Tiago; Ribeiro, Franclim R; Paulo, Paula; Teixeira, Manuel R.; Oliveira, Jorge; Lothe, Ragnhild A; Lind, Guro Elisabeth; Henrique, Rui & Jerónimo, Carmen (2014). Epigenetic regulation of EFEMP1 in prostate cancer: biological relevance and clinical potential. Journal of Cellular and Molecular Medicine.  ISSN 1582-1838.  18(11), s 2287- 2297 . doi: 10.1111/jcmm.12394
  • Bethge, Nicole; Lothe, Ragnhild A; Honne, Hilde; Andresen, Kim; Trøen, Gunhild; Eknæs, Mette; Liestøl, Knut; Holte, Harald; Delabie, Jan; Smeland, Erlend B & Lind, Guro Elisabeth (2014). Colorectal cancer DNA methylation marker panel validated with high performance in Non-Hodgkin lymphoma. Epigenetics.  ISSN 1559-2294.  9(3), s 428- 436 . doi: 10.4161/epi.27554
  • Bruun, Jarle; Kolberg, Matthias; Nesland, Jahn M; Svindland, Aud; Nesbakken, Arild & Lothe, Ragnhild A (2014). Prognostic significance of β-catenin, E-cadherin, and SOX9 in colorectal cancer: Results from a large population-representative series. Frontiers in Oncology.  ISSN 2234-943X.  4 MAY . doi: 10.3389/fonc.2014.00118
  • Hveem, Tarjei Sveinsgjerd; Merok, Marianne Aarstad; Pretorius, Maria; Novelli, Marco; Silihagen, Mette; Sjo, Ole Helmer; Clinch, N; Liestøl, Knut; Svindland, Aud; Lothe, Ragnhild A; Nesbakken, Arild & Danielsen, Håvard Emil (2014). Prognostic impact of genomic instability in colorectal cancer. British Journal of Cancer.  ISSN 0007-0920.  110(8), s 2159- 2164 . doi: 10.1038/bjc.2014.133
  • Løvf, Marthe; Nome, Torfinn; Bruun, Jarle; Eknæs, Mette; Bakken, Anne Cathrine; Mpindi, John-Patrick; Kilpinen, Sami; Rognum, Torleiv Ole; Nesbakken, Arild; Kallioniemi, Olli; Lothe, Ragnhild A & Skotheim, Rolf Inge (2014). A novel transcript, VNN1-AB, as a biomarker for colorectal cancer. International Journal of Cancer.  ISSN 0020-7136.  135(9), s 2077- 2084 . doi: 10.1002/ijc.28855
  • Smebye, Marianne Lislerud; Sveen, Anita; Haugom, Lisbeth; Davidson, Ben; Tropé, Claes Gøran; Lothe, Ragnhild A; Heim, Sverre; Skotheim, Rolf Inge & Micci, Francesca (2014). Chromosome 19 rearrangements in ovarian carcinomas: Zinc finger genes are particularly targeted. Genes, Chromosomes and Cancer.  ISSN 1045-2257.  53(7), s 558- 567 . doi: 10.1002/gcc.22166
  • Sveen, Anita; Johannessen, Bjarne; Teixeira, Manuel; Lothe, Ragnhild A & Skotheim, Rolf Inge (2014). Transcriptome instability as a molecular pan-cancer characteristic of carcinomas. BMC Genomics.  ISSN 1471-2164.  15(1) . doi: 10.1186/1471-2164-15-672
  • Vedeld, Hege Marie; Skotheim, Rolf Inge; Lothe, Ragnhild A & Lind, Guro Elisabeth (2014). The recently suggested intestinal cancer stem cell marker DCLK1 is an epigenetic biomarker for colorectal cancer. Epigenetics.  ISSN 1559-2294.  9(3), s 346- 350 . doi: 10.4161/epi.27582
  • Alagaratnam, Sharmini; Harrison, Neil; Bakken, Anne Cathrine; Hoff, Andreas Midbøe; Jones, Mark; Sveen, Anita; Moore, Harry D.; Andrews, Peter W.; Lothe, Ragnhild A & Skotheim, Rolf Inge (2013). Transforming Pluripotency: An Exon-Level Study of Malignancy-Specific Transcripts in Human Embryonal Carcinoma and Embryonic Stem Cells. Stem Cells and Development.  ISSN 1547-3287.  22(7), s 1136- 1146 . doi: 10.1089/scd.2012.0369
  • Berg, Marianne; Guriby, Marianne; Nordgård, Oddmund; Nedrebø, Bjørn Steinar Olden; Ahlquist, Terje Cruickshank; Smaaland, Rune; Oltedal, Satu; Søreide, Jon Arne; Kørner, Hartwig; Lothe, Ragnhild A & Søreide, Kjetil (2013). Influence of microsatellite instability and KRAS and BRAF mutations on lymph node harvest in stage I–III colon cancers. Molecular medicine (Cambridge, Mass. Print).  ISSN 1076-1551.  19, s 286- 293 . doi: 10.2119/molmed.2013.00049 Full text in Research Archive.
  • Chung, Charles C.; Kanetsky, Peter A.; Wang, Zhaoming; Hildebrandt, Michelle A.T.; Koster, Roelof; Skotheim, Rolf Inge; Kratz, Christian P.; Turnbull, Clare; Cortessis, Victoria K.; Bakken, Anne Cathrine; Bishop, D. Timothy; Cook, Michael B.; Erickson, R. Loren; Fosså, Sophie Dorothea; Jacobs, Kevin B.; Korde, Larissa A.; Kraggerud, Sigrid M.; Lothe, Ragnhild A; Loud, Jennifer T.; Rahman, Nazneen; Skinner, Eila C.; Thomas, Duncan C.; Wu, Xifeng; Yeager, Meredith; Schumacher, Frecrick R.; Greene, Mark H.; Schwartz, Stephen M.; McGlynn, Katherine A.; Chanock, Stephen J. & Nathanson, Katherine L. (2013). Meta-analysis identifies four new loci associated with testicular germ cell tumor. Nature Genetics.  ISSN 1061-4036.  45(6), s 680- 685 . doi: 10.1038/ng.2634
  • Eide, Peter Andreas Wold; Cekaite, Lina; Danielsen, Stine Aske; Kjenseth, Ane Hansen; Fykerud, Tone; Ågesen, Trude Holmeide; Bruun, Jarle; Rivedal, Edgar; Lothe, Ragnhild A; Leithe, Edward & Eilertsen, Ina Andrassy (2013). NEDD4 is overexpressed in colorectal cancer and promotes colonic cell growth independently of the PI3K/PTEN/AKT pathway. Cellular Signalling.  ISSN 0898-6568.  25(1), s 12- 18 . doi: 10.1016/j.cellsig.2012.08.012
  • Kolberg, Matthias; Høland, Maren; Ågesen, Trude Holmeide; Brekke, Helge Roar; Liestøl, Knut; Hall, Kirsten Sundby; Mertens, Fredrik; Picci, Piero; Smeland, Sigbjørn & Lothe, Ragnhild A (2013). Survival meta-analyses for > 1800 malignant peripheral nerve sheath tumor patients with and without neurofibromatosis type 1. Neuro-Oncology.  ISSN 1522-8517.  15(2), s 135- 147 . doi: 10.1093/neuonc/nos287
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  • Nyquist, Kaja Beate; Panagopoulos, Ioannis; Thorsen, Jim; Haugom, Lisbeth; Gorunova, Ludmila; Bjerkehagen, Bodil; Fosså, Alexander; Guriby, Marianne; Nome, Torfinn; Lothe, Ragnhild A; Skotheim, Rolf Inge; Heim, Sverre & Micci, Francesca (2012). Whole-Transcriptome Sequencing Identifies Novel IRF2BP2-CDX1 Fusion Gene Brought about by Translocation t(1;5)(q42;q32) in Mesenchymal Chondrosarcoma. PLoS ONE.  ISSN 1932-6203.  7(11) . doi: 10.1371/journal.pone.0049705
  • Paulo, Paula; Barros-Silva, Joao D.; Ribeiro, Franclim R; Ramalho-Carvalho, Joao; Jeronimo, Carmen; Henrique, Rui; Lind, Guro Elisabeth; Skotheim, Rolf Inge; Lothe, Ragnhild A & Teixeira, Manuel (2012). FLI1 is a novel ETS transcription factor involved in gene fusions in prostate cancer. Genes, Chromosomes and Cancer.  ISSN 1045-2257.  51(3), s 240- 249 . doi: 10.1002/gcc.20948
  • Paulo, Paula; Ribeiro, Franclim R; Santos, Joana; Mesquita, Diana; Almeida, Mafalda; Barros-Silva, Joao D.; Itkonen, Harri; Henrique, Rui; Jeronimo, Carmen; Sveen, Anita; Mills, Ian Geoffrey; Skotheim, Rolf Inge; Lothe, Ragnhild A & Teixeira, Manuel (2012). Molecular Subtyping of Primary Prostate Cancer Reveals Specific and Shared Target Genes of Different ETS Rearrangements. Neoplasia.  ISSN 1522-8002.  14(7), s 600- +
  • Sirnes, Solveig; Bruun, Jarle; Kolberg, Matthias; Kjenseth, Ane Hansen; Lind, Guro Elisabeth; Svindland, Aud; Brech, Andreas; Nesbakken, Arild; Lothe, Ragnhild A; Leithe, Edward & Rivedal, Edgar (2012). Connexin43 acts as a colorectal cancer tumor suppressor and predicts disease outcome. International Journal of Cancer.  ISSN 0020-7136.  131(3), s 570- 581 . doi: 10.1002/ijc.26392
  • Sveen, Anita; Bakken, Anne Cathrine; Ågesen, Trude Holmeide; Lind, Guro Elisabeth; Nesbakken, Arild; Nordgård, Oddmund; Brackmann, Stephan; Rognum, Torleiv Ole; Lothe, Ragnhild A & Skotheim, Rolf Inge (2012). The exon-level biomarker SLC39A14 has organ-confined cancer-specificity in colorectal cancer. International Journal of Cancer.  ISSN 0020-7136.  131(6), s 1479- 1485 . doi: 10.1002/ijc.27399
  • Sveen, Anita; Ågesen, Trude Holmeide; Nesbakken, Arild; Meling, Gunn Iren; Rognum, Torleiv Ole; Liestøl, Knut; Skotheim, Rolf Inge & Lothe, Ragnhild A (2012). ColoGuidePro: A Prognostic 7-Gene Expression Signature for Stage III Colorectal Cancer Patients. Clinical Cancer Research.  ISSN 1078-0432.  18(21), s 6001- 6010 . doi: 10.1158/1078-0432.CCR-11-3302
  • Ågesen, Trude Holmeide; Sveen, Anita; Merok, Marianne Aarstad; Lind, Guro Elisabeth; Nesbakken, Arild; Skotheim, Rolf Inge & Lothe, Ragnhild A (2012). ColoGuideEx: a robust gene classifier specific for stage II colorectal cancer prognosis. Gut.  ISSN 0017-5749.  61(11), s 1560- 1567 . doi: 10.1136/gutjnl-2011-301179
  • Alagaratnam, Sharmini; Lind, Guro Elisabeth; Kraggerud, Sigrid M.; Lothe, Ragnhild A & Skotheim, Rolf Inge (2011). The testicular germ cell tumour transcriptome. International Journal of Andrology.  ISSN 0105-6263.  34(4pt2), s e133- e151 . doi: 10.1111/j.1365-2605.2011.01169.x
  • Ali, Deeqa Ahmed Mohamed; Lothe, Ragnhild A; Rivedal, Edgar & Lind, Guro Elisabeth (2011). Quantitative validation of GJC1 promoter hypermethylation in benign and malignant colorectal tumors. Endocrine-Related Cancer.  ISSN 1351-0088.  18(6), s C31- C34 . doi: 10.1530/ERC-11-0204
  • Berge, Gisle; Costea, Daniela Elena; Rasmussen, Marianne Berg; Rasmussen, Heidi; Grotterød, Ida; Lothe, Ragnhild A; Mælandsmo, Gunhild & Flatmark, Kjersti (2011). Coexpression and nuclear colocalization of metastasis-promoting protein S100A4 and p53 without mutual regulation in colorectal carcinoma. Amino Acids.  ISSN 0939-4451.  41(4), s 875- 884 . doi: 10.1007/s00726-010-0514-6 Show summary
  • Costa, Vera L.; Henrique, Rui; Danielsen, Stine Aske; Eknæs, Mette; Patrcio, Patricia; Morais, Antonio; Oliveira, Jorge; Lothe, Ragnhild A; Teixeira, Manuel; Lind, Guro Elisabeth & Jeronimo, Carmen (2011). TCF21 and PCDH17 methylation An innovative panel of biomarkers for a simultaneous detection of urological cancers. Epigenetics.  ISSN 1559-2294.  6(9), s 1120- 1130 . doi: 10.4161/epi.6.9.16376
  • Danielsen, Stine Aske; Cekaite, Lina; Ågesen, Trude Holmeide; Sveen, Anita; Nesbakken, Arild; Thiis-Evensen, Espen; Skotheim, Rolf Inge; Lind, Guro Elisabeth & Lothe, Ragnhild A (2011). Phospholipase C Isozymes Are Deregulated in Colorectal Cancer - Insights Gained from Gene Set Enrichment Analysis of the Transcriptome. PLoS ONE.  ISSN 1932-6203.  6(9) . doi: 10.1371/journal.pone.0024419
  • Lind, Guro Elisabeth; Danielsen, Stine Aske; Ahlquist, Terje Cruickshank; Merok, Marianne Aarstad; Andresen, Kim; Skotheim, Rolf Inge; Hektoen, Merete; Rognum, Torleiv Ole; Meling, Gunn Iren; Hoff, Geir; Bretthauer, Michael; Thiis-Evensen, Espen; Nesbakken, Arild & Lothe, Ragnhild A (2011). Identification of an epigenetic biomarker panel with high sensitivity and specificity for colorectal cancer and adenomas. Molecular Cancer.  ISSN 1476-4598.  10 . doi: 10.1186/1476-4598-10-85
  • Lind, Guro Elisabeth; Raiborg, Camilla; Danielsen, Stine Aske; Rognum, Torleiv Ole; Thiis-Evensen, Espen; Hoff, Geir; Nesbakken, Arild; Stenmark, Harald & Lothe, Ragnhild A (2011). SPG20, a novel biomarker for early detection of colorectal cancer, encodes a regulator of cytokinesis. Oncogene.  ISSN 0950-9232.  30(37), s 3967- 3978 . doi: 10.1038/onc.2011.109
  • Løvf, Marthe; Thomassen, Gard O Sundby; Bakken, Anne Cathrine; Celestino, Ricardo; Fioretos, Thoas; Lind, Guro Elisabeth; Lothe, Ragnhild A & Skotheim, Rolf Inge (2011). Fusion Gene Microarray Reveals Cancer Type-Specificity Among Fusion Genes. Genes, Chromosomes and Cancer.  ISSN 1045-2257.  50(5), s 348- 357 . doi: 10.1002/gcc.20860
  • Ohnstad, Hege Oma; Paulsen, Erik Braarød; Noordhuis, Paul; Berg, Marianne; Lothe, Ragnhild A; Vassilev, Lyubomir T. & Myklebost, Ola (2011). MDM2 antagonist Nutlin-3a potentiates antitumour activity of cytotoxic drugs in sarcoma cell lines. BMC Cancer.  ISSN 1471-2407.  11 . doi: 10.1186/1471-2407-11-211
  • Ribeiro, Franclim R; Paulo, Paula; Costa, Vera L; Barros-Silva, Joao D.; Ramalho-Carvalho, Joao; Jeronimo, Carmen; Henrique, Rui; Lind, Guro Elisabeth; Skotheim, Rolf Inge; Lothe, Ragnhild A & Teixeira, Manuel (2011). Cysteine-Rich Secretory Protein-3 (CRISP3) Is Strongly Up-Regulated in Prostate Carcinomas with the TMPRSS2-ERG Fusion Gene. PLoS ONE.  ISSN 1932-6203.  6(7), s e22317 . doi: 10.1371/journal.pone.0022317
  • Sirnes, Solveig; Honne, Hilde; Danielsen, Stine Aske; Ali, Deeqa Ahmed Mohamed; Rognum, Torleiv Ole; Meling, Gunn Iren; Leithe, Edward; Rivedal, Edgar; Lothe, Ragnhild A & Lind, Guro Elisabeth (2011). DNA methylation analyses of the connexin gene family reveal silencing of GJC1 (Connexin45) by promoter hypermethylation in colorectal cancer. Epigenetics.  ISSN 1559-2294.  6(5), s 602- 609 . doi: 10.4161/epi.6.5.15237
  • Sjo, Ole Helmer; Berg, Marianne; Merok, Marianne Aarstad; Kolberg, Matthias; Svindland, Aud; Lothe, Ragnhild A & Nesbakken, Arild (2011). Peritoneal Carcinomatosis of Colon Cancer Origin: Highest Incidence in Women and in Patients With Right-Sided Tumors. Journal of Surgical Oncology.  ISSN 0022-4790.  104(7), s 792- 797 . doi: 10.1002/jso.21959
  • Sveen, Anita; Ågesen, Trude Holmeide; Nesbakken, Arild; Rognum, Torleiv Ole; Lothe, Ragnhild A & Skotheim, Rolf Inge (2011). Transcriptome instability in colorectal cancer identified by exon microarray analyses: Associations with splicing factor expression levels and patient survival. Genome Medicine.  ISSN 1756-994X.  3(5) . doi: 10.1186/gm248
  • Ågesen, Trude Holmeide; Berg, Marianne; Clancy, Trevor; Thiis-Evensen, Espen; Cekaite, Lina; Lind, Guro Elisabeth; Nesland, Jahn M; Bakka, Arne Olav; Mala, Tom; Hauss, Hans Joakim; Fetveit, T; Vatn, Morten H; Hovig, Eivind; Nesbakken, Arild; Lothe, Ragnhild A & Skotheim, Rolf Inge (2011). CLC and IFNAR1 are differentially expressed and a global immunity score is distinct between early- and late-onset colorectal cancer. Genes and Immunity.  ISSN 1466-4879.  12(8), s 653- 662 . doi: 10.1038/gene.2011.43

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Published Apr. 13, 2011 2:55 PM - Last modified Feb. 13, 2012 10:55 AM