Sigbjørn Dimmen

• Solaiman, Rafat H.; Dirnberger, Jack; Kennedy, Nicholas I.; DePhillipo, Nicholas; Tagliero, Adam J. & Malinowski, Konrad [Show all 8 contributors for this article] (2024). The effect of nonsteroidal anti-inflammatory drug use on soft tissue and bone healing in the knee: a systematic review. Annals of Joint. ISSN 2415-6809. 9, p. 1–10. doi: 10.21037/aoj-23-58.
• Dimmen, Sigbjørn; Owesen, Christian; Lundgreen, Kirsten & Jenssen, Kjersti Kaul (2022). No difference in clinical outcome after rotator cuff repair performed within or later than 3 months after trauma: a retrospective cohort study. Knee Surgery, Sports Traumatology, Arthroscopy. ISSN 0942-2056. doi: 10.1007/s00167-022-07193-y. Full text in Research Archive
• Eigenschink, Martin; Heuberer, Philipp R.; Pauzenberger, Leo; Garrigues, Grant E.; Achenbach, Leonard & Dimmen, Sigbjørn [Show all 8 contributors for this article] (2021). Allo- and autografts show comparable outcomes in chronic acromioclavicular joint reconstruction: a systematic review. Knee Surgery, Sports Traumatology, Arthroscopy. ISSN 0942-2056. doi: 10.1007/s00167-021-06445-7.
• Ekeland, Arne Erling; Nerhus, Tor Kjetil; Dimmen, Sigbjørn & Heir, Stig (2020). Better functional results of opening wedge HTO for varus knees with medial osteoarthritis than opening wedge LFO for valgus knees with lateral osteoarthritis. A prospective study with 10-year follow-up. Bone & Joint Open (BJO). ISSN 2633-1462. 1(7), p. 346–354. doi: 10.1302/2633-1462.17.BJO-2020-0081.R1.
• Hjorthaug, Geir Aasmund; Søreide, Endre; Nordsletten, Lars; Madsen, Jan Erik; Reinholt, Finn P. & Niratisairak, Sanyalak [Show all 7 contributors for this article] (2019). Short-term perioperative parecoxib is not detrimental to shaft fracture healing in a rat model. Bone and Joint Research. ISSN 2046-3758. 8(10), p. 472–480. doi: 10.1302/2046-3758.810.BJR-2018-0341.R1.
• Strauss, Marc Jacob; Varatojo, Ricardo; Boutefnouchet, Tarek; Condello, Vincenzo; Samuelsson, Kristian & Gelber, Pablo E. [Show all 12 contributors for this article] (2019). The use of allograft tissue in posterior cruciate, collateral and multi-ligament knee reconstruction. Knee Surgery, Sports Traumatology, Arthroscopy. ISSN 0942-2056. 27(6), p. 1791–1809. doi: 10.1007/s00167-019-05426-1. Show summary

  Purpose: Currently both autograft and allograft tissues are available for reconstruction of posterior cruciate, collateral and multi-ligament knee injuries. Decision-making is based on a complex interplay between anatomical structures, functional bundles and varying biomechanical requirements. Despite theoretically better biological healing and reduced risk of disease transmission autografts are associated with donor site morbidity as well as being limited by size and quantity. The use of allografts eliminates donor-site morbidity but raises cost and issues of clinical effectiveness. The purpose of this paper is to review current concepts and evidence for the use of allografts in primary posterior cruciate, collateral and multi-ligament reconstructions. Methods: A narrative review of the relevant literature was conducted for PCL, collateral ligament and multi-ligament knee reconstruction. Studies were identified using a targeted and systematic search with focus on recent comparative studies and all clinical systematic reviews and meta-analyses. The rationale and principles of management underpinning the role of allograft tissue were identified and the clinical and functional outcomes were analysed. Finally, the position of postoperative physiotherapy and rehabilitation was identified. Results: The review demonstrated paucity in high quality and up-to-date results addressing the issue especially on collaterals and multi-ligament reconstructions. There was no significant evidence of superiority of a graft type over another for PCL reconstruction. Contemporary principles in the management of posterolateral corner, MCL and multi-ligament injuries support the use of allograft tissue. Conclusion: The present review demonstrates equivalent clinical results with the use of autografts or allografts. It remains, however, difficult to generate a conclusive evidence-based approach due to the paucity of high-level research. When confronted by the need for combined reconstructions with multiple grafts, preservation of synergistic muscles, and adapted postoperative rehabilitation; the current evidence does offer support for the use of allograft tissue.

• Condello, Vincenzo; Zdanowicz, Urszula; Di Matteo, Berardo; Spalding, Tim; Gelber, Pablo E. & Adravanti, Paolo [Show all 12 contributors for this article] (2018). Allograft tendons are a safe and effective option for revision ACL reconstruction: a clinical review. Knee Surgery, Sports Traumatology, Arthroscopy. ISSN 0942-2056. doi: 10.1007/s00167-018-5147-4.
• Lundgreen, Kirsten; Madsen, Jan Erik; KVAKESTAD, RUNE; Dimmen, Sigbjørn & Jenssen, Kjersti Kaul (2018). Prognostic Factors for Functional Outcome After Rotator Cuff Repair: A Prospective Cohort Study With 2-Year Follow-up. American Journal of Sports Medicine. ISSN 0363-5465. 46(14), p. 3463–3470. doi: 10.1177/0363546518803331.
• Jenssen, Kjersti Kaul; Lundgreen, Kirsten; Madsen, Jan Erik; Kvakestad, Rune; Pripp, Are Hugo & Dimmen, Sigbjørn (2018). No functional difference between three and six weeks of immobilization after arthroscopic rotator cuff repair: A Prospective randomized controlled non-inferiority trial. Arthroscopy: The Journal of Arthroscopy And Related. ISSN 0749-8063. 34(10), p. 2765–2774. doi: 10.1016/j.arthro.2018.05.036.
• Hjorthaug, Geir Aasmund; Søreide, Endre; Nordsletten, Lars; Madsen, Jan Erik; Reinholt, Finn P. & Niratisairak, Sanyalak [Show all 7 contributors for this article] (2018). Negative effect of zoledronic acid on tendon-to-bone healing: In vivo study of biomechanics and bone remodeling in a rat model. Acta Orthopaedica. ISSN 1745-3674. 89(3), p. 360–366. doi: 10.1080/17453674.2018.1440189. Full text in Research Archive
• Jenssen, Kjersti Kaul; Lundgreen, Kirsten; Madsen, Jan Erik & Dimmen, Sigbjørn (2017). Targeted intervention of acute postoperative infection after rotator cuff repair results in good functional outcomes. Knee Surgery, Sports Traumatology, Arthroscopy. ISSN 0942-2056. 26(1), p. 285–291. doi: 10.1007/s00167-017-4743-z.
• Ekeland, Arne Erling; Nerhus, Tor Kjetil; Dimmen, Sigbjørn; Thornes, Elisabeth & Heir, Stig (2017). Good functional results following high tibial opening-wedge osteotomy of knees with medial osteoarthritis: A prospective study with a mean of 8.3 years of follow-up. Knee (Oxford). ISSN 0968-0160. 24(2), p. 380–389. doi: 10.1016/j.knee.2016.12.005.
• Søreide, Endre; Granan, Lars-Petter; Hjorthaug, Geir Aasmund; Espehaug, Birgitte; Dimmen, Sigbjørn & Nordsletten, Lars (2016). The effect of limited perioperative nonsteroidal anti-inflammatory drugs on patients undergoing anterior cruciate ligament reconstruction. American Journal of Sports Medicine. ISSN 0363-5465. 44(12), p. 3111–3118. doi: 10.1177/0363546516657539. Show summary

  Background: The administration of nonsteroidal anti-inflammatory drugs (NSAIDs) to patients undergoing anterior cruciate ligament reconstruction (ACLR) is controversial because it may impair tissue healing and clinical outcomes. Purpose: To assess the effect of NSAID administration on patients undergoing ACLR. Study Design: Cohort study; Level of evidence, 3. Methods: Included patients were aged >15 years and were registered in the Norwegian Knee Ligament Registry from 2008 until 2013 after the primary ACLR. Patients with insufficient data regarding administration of NSAIDs and those with associated knee ligament injuries requiring surgical treatment were excluded from this study. Graft survival was estimated using Kaplan-Meier survival curves, and hazard ratios (HRs) for revision were evaluated using Cox regression analysis. Logistic regression analysis was used to calculate the odds ratio (OR) for a Knee Injury and Osteoarthritis Outcome Score (KOOS)–quality of life (QOL) subscale score <44 at 2-year follow-up. Results: A total of 7822 patients were included in the analysis for graft survival and assessment for risk of revision. Of these, 4144 patients were administered NSAIDs postoperatively. The mean duration of follow-up was 2.8 years (range, 0-5.9 years). Administration of NSAIDs did not influence graft survival (P = .568). Adjusted Cox regression analyses demonstrated the same finding regarding risk of revision (HR, 1.0; 95% CI, 0.8-1.3). ACLR using a bone–patellar tendon–bone autograft showed a reduced risk of revision (HR, 0.3; 95% CI, 0.1-0.8) among patients administered NSAIDs. In subgroup analyses of 3144 patients, administration of NSAIDs demonstrated a beneficial effect on the risk of a KOOS-QOL score <44 at 2-year follow-up (OR, 0.8; 95% CI, 0.6-0.9). Conclusion: Administration of NSAIDs to patients after ACLR does not have a negative effect on graft survival, risk of revision, or risk of a KOOS-QOL score <44 at 2-year follow-up. We emphasize using caution when administering NSAIDs by keeping the duration and dosage of NSAIDs as short and low as possible to ensure sufficient pain relief while limiting unwanted exposure to any known and unknown adverse effects of these drugs.

• Ekeland, Arne Erling; Nerhus, Tor Kjetil; Dimmen, Sigbjørn & Heir, Stig (2016). Good functional results of distal femoral opening-wedge osteotomy of knees with lateral osteoarthritis. Knee Surgery, Sports Traumatology, Arthroscopy. ISSN 0942-2056. 24(5), p. 1702–1709. doi: 10.1007/s00167-016-3988-2.
• Amlie, Einar Johan Braém; Lerdal, Anners; Gay, Caryl; Høvik, Øystein; Nordsletten, Lars & Dimmen, Sigbjørn (2016). A trend for increased risk of revision surgery due to deep infection following fast-track hip arthroplasty. Advances in Orthopedics. ISSN 2090-3464. doi: 10.1155/2016/7901953. Full text in Research Archive
• Hjorthaug, Geir Aasmund; Madsen, Jan Erik; Nordsletten, Lars; Reinholt, Finn P.; Steen, Harald & Dimmen, Sigbjørn (2015). Tendon to bone tunnel healing - A study on the time-dependent changes in biomechanics, bone remodeling, and histology in a rat model. Journal of Orthopaedic Research. ISSN 0736-0266. 33(2), p. 216–223. doi: 10.1002/jor.22756.
• Amlie, Einar Johan Braém; Havelin, Leif Ivar; Furnes, Ove; Baste, Valborg; Nordsletten, Lars & Høvik, Øystein [Show all 7 contributors for this article] (2014). Worse patient-reported outcome after lateral approach than after anterior and posterolateral approach in primary hip arthroplasty. A cross-sectional questionnaire study of 1,476 patients 1-3 years after surgery. Acta Orthopaedica. ISSN 1745-3674. 85(5), p. 463–469. doi: 10.3109/17453674.2014.934183. Full text in Research Archive
• Dimmen, Sigbjørn (2011). Effects of cox inhibitors on bone and tendon healing. Acta Orthopaedica. ISSN 1745-3674. 82, p. 1–22. doi: 10.3109/17453674.2011.555370.
• Dimmen, Sigbjørn (2011). Effects of cox inhibitors on bone and tendon healing Introduction. Acta Orthopaedica. ISSN 1745-3674. 82, p. 4–22. doi: 10.3109/17453674.2011.555370.
• Dimmen, Sigbjørn; Nordsletten, Lars; Engebretsen, Lars; Steen, Harald & Madsen, Jan Erik (2009). The effect of parecoxib and indometacin on tendon-to-bone healing in a bone tunnel AN EXPERIMENTAL STUDY IN RATS. Journal of Bone and Joint Surgery (JBJS). ISSN 0301-620X. 91B(2), p. 259–263. doi: 10.1302/0301-620X.91B2.21471.
• Dimmen, Sigbjørn; Nordsletten, Lars & Madsen, Jan Erik (2009). Parecoxib and Indomethacin Delay Early Fracture Healing: A Study in Rats. Clinical Orthopaedics and Related Research. ISSN 0009-921X. 467(8), p. 1992–1999. doi: 10.1007/s11999-009-0783-0.
• Dimmen, Sigbjørn; Engebretsen, Lars; Nordsletten, Lars & Madsen, Jan Erik (2009). Negative effects of parecoxib and indomethacin on tendon healing: an experimental study in rats. Knee Surgery, Sports Traumatology, Arthroscopy. ISSN 0942-2056. 17(7), p. 835–839. doi: 10.1007/s00167-009-0763-7.
• Dimmen, Sigbjørn; Nordsletten, Lars; Engebretsen, Lars; Steen, Harald & Madsen, Jan Erik (2008). Negative effect of parecoxib on bone mineral during fracture healing in rats. Acta Orthopaedica. ISSN 1745-3674. 79, p. 438–444. doi: 10.1080/17453670710015373.
• Dimmen, Sigbjørn & Madsen, Jan Erik (2007). Long term outcome of shoulder arthrodesis performed with plate fixation: 18 patients examined after 3-15 years. Acta Orthopaedica. ISSN 1745-3674. 78(6), p. 827–833.

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• Torp-Joakimsen, Kjell Aage Moe; Dimmen, Sigbjørn & Stubhaug, Audun (2022). Local infiltration analgesia versus interscalene nerve block for postoperative pain control after primary shoulder arthroplasty: A retrospective study including 100 patients. Show summary

  Abstract Background: The aim of this study was to compare the efficacy of single bolus local infiltration analgesia (LIA) versus continous interscalene nerve block (ISB) for early postoperative pain control after total shoulder arthroplasty (TSA). The null hypothesis was no difference between treatments. Methods: A retrospective study including patients from 2021.05.01 and backwards in time until both groups had included 50 patients. All patients who underwent primary TSA for shoulder osteoarthritis were eligible for inclusion. Patients in the ISB group received a perineural catheter at the ipsilateral interscalene plexus prior to operation, and after a preoperative bolus of local anaesthetic had a postoperative continous infusion of ropivacaine 2 mg/ml for up to 2 days. For the LIA group, the surgeon injected a weight dependent dose of 2 mg/ml ropivacaine with epinephrine intraoperatively. The primary outcome was mean opoid consumption @ 1,4,24 and 48-hour postoperatively. The secondary outcomes were opioid consumption perioperatively, complications and need for adjuvant pain treatment as lidocaine or ketamine infusions or clonidine boluses. The sample size was calculated with an α=0,05 and β=0,2. Results: The study included 100 patients (50 LIA and 50 ISB patients) with comparable patient group regarding age, weight, height, sex, ASA-status and preoperative CN symptome score. For all time points the first 24 hours, the ISB group had a significantly lower opioid consumption. The final 24 hour opoid consumptions were similar, but the total 48 hour opoid consumption was significantly lower in the ISB-group. Secondarily the perioperative opoid consumption was statistcally lower in the ISB group, and the LIA group had significantly more need for adjuvants. Most excluded patients in the LIA group had to resort to a rescue ISB postoperatively. Conclusion: Continous ISB is superior for early postoperative pain control after TSA compared to a single bolus LIA group using MEQ as endpoint. Keywords: Total shoulder arthroplasty; early postoperative pain; interscalene nerve block; local infiltration analgesia; opioid consumption.

• Madsen, Jan Erik; Dimmen, Sigbjørn & Siewers, P. (2004). Long-term functional results after shoulder arthrodesis in 15 patients after 7.8 (2-20) years.
• Dimmen, Sigbjørn; Nordsletten, Lars; Engebretsen, Lars & Madsen, Jan Erik (2004). Effekt av parecoxib på bentilheling.
• Dimmen, Sigbjørn; Madsen, Jan Erik; Nordsletten, Lars & Engebretsen, Lars (2004). Effects of parecoxib on bone healing.
• Dimmen, Sigbjørn & Madsen, Jan Erik (2010). Effects of cox inhibitors on bone and tendon healing. Unipub forlag. ISSN 978-82-8072-595-0.

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