Tina Ellinor Rosland

• Rosland, Tina Ellinor; Johansen, Nora; Liavaag, Astrid Helene; Åsvold, Bjørn Olav; Pripp, Are Hugo & Michelsen, Trond Melbye (2026). All-cause mortality after self-reported vs. hospital-reported gynecological surgery: The HUNT study. Acta Obstetricia et Gynecologica Scandinavica. ISSN 0001-6349. p. 1–10. doi: 10.1111/aogs.70354. Full text in Research Archive
• Rosland, Tina Ellinor; Johansen, Nora; Åsvold, Bjørn Olav; Pripp, Are Hugo; Liavaag, Astrid Helene & Michelsen, Trond Melbye (2024). Validity of self-reported hysterectomy and oophorectomy in a population-based cohort: The HUNT study. BJOG: An International Journal of Obstetrics and Gynaecology. ISSN 1470-0328. 131(11), p. 1555–1562. doi: 10.1111/1471-0528.17859. Full text in Research Archive Show summary

  Objective: To validate self-reported hysterectomy and bilateral oophorectomy. Design: Validation study. Setting: Large population-based cohort study in Norway: The Trøndelag Health Study (HUNT). Population: The Trøndelag Health Study 2 and 3 (HUNT2 and HUNT3) included questions on gynaecological history. Women who answered questions regarding hysterectomy and/or oophorectomy were included. In total, 30 263 women were included from HUNT2 (1995–1997) and 23 138 from HUNT3 (2006–2008), of which 16 261 attended both HUNT2 and HUNT3. Methods: We compared self-reported hysterectomy and bilateral oophorectomy with electronic hospital procedure codes. Main outcome measures: Sensitivity, specificity, positive predictive value and negative predictive value of self-reported hysterectomy and bilateral oophorectomy, by comparing with hospital procedure codes. Results: Self-reported hysterectomy and bilateral oophorectomy in HUNT2 and/or HUNT3 both had specificity and negative predictive value above 99%. Self-reported hysterectomy had a sensitivity of 95.9%, and for bilateral oophorectomy sensitivity was 91.2%. Positive predictive value of self-reported hysterectomy was 85.8%, but for self-reported bilateral oophorectomy it was 65.4%. Conclusions: Self-reported hysterectomy corresponded quite well with hospital data and can be used in epidemiological studies. Self-reported bilateral oophorectomy, on the other hand, had low positive predictive value, and results based on such data should be interpreted with caution. Women who report no previous hysterectomy or bilateral oophorectomy can safely be classified as unexposed to these surgeries.

• Michelsen, Trond Melbye; Rosland, Tina Ellinor; Åsvold, Bjørn Olav; Pripp, Are Hugo; Liavaag, Astrid Helene & Johansen, Nora (2023). All-cause and cardiovascular mortality after hysterectomy and oophorectomy in a large cohort (HUNT2). Acta Obstetricia et Gynecologica Scandinavica. ISSN 0001-6349. 102(4), p. 465–472. doi: 10.1111/aogs.14531. Full text in Research Archive Show summary

  Introduction Hysterectomy and bilateral oophorectomy are common major surgical procedures that have been associated with increased mortality risk. We aimed to assess the association of hysterectomy and/or bilateral oophorectomy with all-cause and cardiovascular mortality in a Norwegian population. Material and methods Cohort study with data from The Trøndelag Health Study (HUNT2) linked to the Norwegian Cause of Death Registry, with follow-up from 1996 until 2014 or death. The unexposed group (n = 18 673) included women with both their ovaries and uterus intact, while the two exposed groups included women with hysterectomy alone (n = 1199), or bilateral oophorectomy with or without hysterectomy (n = 907). We compared mortality in exposed vs unexposed groups and adjusted for relevant covariates by Cox regression. Further, we performed analyses stratified by age at surgery (≤39, 40–52, ≥53 years) and subgroup analyses among women ≤52 years of age at inclusion. Results Among the 47 312 women in HUNT2 (1995–1997), 20 779 provided complete information regarding gynecological surgery and previous health. The hysterectomy group had increased all-cause mortality (hazard ratio [HR] 1.30, 95% confidence interval [CI] 1.06–1.58) and cardiovascular mortality (HR 1.47, 95% CI 1.09–1.97). We found no significant association between bilateral oophorectomy and all-cause or cardiovascular mortality in the total population. However, among women ≤52 years at inclusion, cardiovascular mortality was increased in the hysterectomy group (HR 2.71, 95% CI 1.19–6.17) with a similar, but less precise estimate in the bilateral oophorectomy group (HR 2.42, 95% CI 0.84–6.93). Conclusions Hysterectomy was associated with increased all-cause and cardiovascular mortality, whereas bilateral salpingo-oophorectomy was not. Among women ≤52 years at inclusion, both hysterectomy and bilateral oophorectomy were associated with a twofold increased risk of cardiovascular mortality, but the results were imprecise. Women after hysterectomy and/or bilateral salpingo-oophorectomy constitute a group with increased cardiovascular mortality that may need closer attention to cardiovascular disease risk from the healthcare system to ensure timely and effective preventive interventions.

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• Rosland, Tina Ellinor (2021). Kan hysterektomi og ooforektomi gi økt dødelighet? Full text in Research Archive

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