Victor Greiff
Associate Professor
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Department of Immunology

Norwegian version of this page
Mobile phone
+47 96690757
Room
A3.2008
Username
Visiting address
Sognsvannsveien 20
Rikshospitalet
0372 Oslo
Postal address
Postboks 4950 Nydalen
OUS HF Rikshospitalet
0424 Oslo
Publications
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Kanduri, Chakravarthi; Pavlović, Milena; Scheffer, Lonneke; Motwani, Keshav; Chernigovskaya, Maria & Greiff, Victor [Show all 7 contributors for this article] (2022). Profiling the baseline performance and limits of machine learning models for adaptive immune receptor repertoire classification. GigaScience. ISSN 2047-217X. 11(05). doi: 10.1093/gigascience/giac046. Full text in Research Archive
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Akbar, Rahmad; Robert, Philippe Paul Auguste; Weber, Cédric R.; Widrich, Michael; Frank, Robert & Pavlovic, Milena [Show all 19 contributors for this article] (2022). In silico proof of principle of machine learning-based antibody design at unconstrained scale. mAbs. ISSN 1942-0862. 14:e2031482(1), p. 1–18. doi: 10.1080/19420862.2022.2031482.
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Grevys, Algirdas; Frick, Rahel; Mester, Simone; Flem-Karlsen, Karine; Nilsen, Jeannette & Foss, Stian [Show all 13 contributors for this article] (2022). Antibody variable sequences have a pronounced effect on cellular transport and plasma half-life. iScience. ISSN 2589-0042. 25(2). doi: 10.1016/j.isci.2022.103746.
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Akbar, Rahmad; Bashour, Habib; Rawat, Puneet; Robert, Philippe Paul Auguste; Smorodina, Eva & Cotet, Tudor-Stefan [Show all 15 contributors for this article] (2022). Progress and challenges for the machine learning-based design of fit-for-purpose monoclonal antibodies. mAbs. ISSN 1942-0862. 14(1). doi: 10.1080/19420862.2021.2008790.
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Dahal-Koirala, Shiva; Balaban, Gabriel; Neumann, Ralf Stefan; Scheffer, Lonneke; Lundin, Knut & Greiff, Victor [Show all 9 contributors for this article] (2022). TCRpower: quantifying the detection power of T-cell receptor sequencing with a novel computational pipeline calibrated by spike-in sequences. Briefings in Bioinformatics. ISSN 1467-5463. doi: 10.1093/bib/bbab566.
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Mathew, Nimitha R.; Kalathilparambil Jayanthan, Jayalal; Smirnov, Ilya V.; Robinson, Jonathan L.; Axelsson, Hannes & Nakka, Sravya S. [Show all 20 contributors for this article] (2021). Single-cell BCR and transcriptome analysis after influenza infection reveals spatiotemporal dynamics of antigen-specific B cells. Cell reports. ISSN 2211-1247. 35:109286(12), p. 1–25. doi: 10.1016/j.celrep.2021.109286. Full text in Research Archive
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Mikocziova, Ivana; Peres, Ayelet; Gidoni, Moriah; Greiff, Victor; Yaari, Gur & Sollid, Ludvig Magne (2021). Germline polymorphisms and alternative splicing of human immunoglobulin light chain genes. iScience. ISSN 2589-0042. 24:103192(10), p. 1–19. doi: 10.1016/j.isci.2021.103192. Full text in Research Archive
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Mikocziova, Ivana; Greiff, Victor & Sollid, Ludvig Magne (2021). Immunoglobulin germline gene variation and its impact on human disease. Genes and Immunity. ISSN 1466-4879. 22(4), p. 205–217. doi: 10.1038/s41435-021-00145-5. Full text in Research Archive
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Amoriello, Roberta; Chernigovskaia, Mariia; Greiff, Victor; Carnasciali, Alberto; Massacesi, Luca & Barilaro, Alessandro [Show all 13 contributors for this article] (2021). TCR repertoire diversity in Multiple Sclerosis: High-dimensional bioinformatics analysis of sequences from brain, cerebrospinal fluid and peripheral blood. EBioMedicine. ISSN 2352-3964. 68:103429, p. 1–13. doi: 10.1016/j.ebiom.2021.103429. Full text in Research Archive
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Robert, Philippe Paul Auguste; Kunze-Schumacher, Heike; Greiff, Victor & Krueger, Andreas (2021). Modeling the dynamics of T-cell development in the thymus. Entropy. ISSN 1099-4300. 23:437(4). doi: 10.3390/e23040437. Full text in Research Archive
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Slabodkin, Andrei; Chernigovskaia, Maria; Mikocziova, Ivana; Akbar, Rahmad; Scheffer, Lonneke & Pavlović, Milena [Show all 16 contributors for this article] (2021). Individualized VDJ recombination predisposes the available Ig sequence space. Genome Research. ISSN 1088-9051. p. 2209–2224. doi: 10.1101/gr.275373.121. Full text in Research Archive
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Pavlović, Milena; Scheffer, Lonneke; Motwani, Keshav; Kanduri, Chakravarthi; Kompova, Radmila & Vazov, Nikolay Aleksandrov [Show all 41 contributors for this article] (2021). The immuneML ecosystem for machine learning analysis of adaptive immune receptor repertoires. Nature Machine Intelligence. 3(11), p. 936–944. doi: 10.1038/s42256-021-00413-z.
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Neumeier, Daniel; Pedrioli, Alessandro; Genovese, Alessandro; Sandu, Ioana; Ehling, Roy & Hong, Kai-Lin [Show all 19 contributors for this article] (2021). Profiling the specificity of clonally expanded plasma cells during chronic viral infection by single-cell analysis. European Journal of Immunology. ISSN 0014-2980. 52(2), p. 297–311. doi: 10.1002/eji.202149331. Full text in Research Archive
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Snapkov, Igor; Chernigovskaia, Maria; Sinitcyn, Pavel; Le, Quy Khang; Nyman, Tuula Anneli & Greiff, Victor (2021). Progress and challenges in mass spectrometry-based analysis of antibody repertoires. Trends in Biotechnology. ISSN 0167-7799. 00, p. 1–19. doi: 10.1016/j.tibtech.2021.08.006. Full text in Research Archive
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Mester, Simone; Evers, Mitchell; Meyer, Saskia; Nilsen, Jeannette; Greiff, Victor & Sandlie, Inger [Show all 8 contributors for this article] (2021). Extended plasma half-life of albumin-binding domain fused human IgA upon pH-dependent albumin engagement of human FcRn in vitro and in vivo. mAbs. ISSN 1942-0862. 13:1893888(1), p. 1–14. doi: 10.1080/19420862.2021.1893888. Full text in Research Archive
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Øjlert, Åsa Kristina; Nebdal, Daniel J.H.; Snapkov, Igor; Olsen, Vibeke; Kidman, Joel & Greiff, Victor [Show all 8 contributors for this article] (2021). Dynamic changes in the T cell receptor repertoire during treatment with radiotherapy combined with an immune checkpoint inhibitor. Molecular Oncology. ISSN 1574-7891. p. 1–11. doi: 10.1002/1878-0261.13082. Full text in Research Archive
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Arnaout, Ramy A.; Luning Prak, Eline T.; Schwab, Nicholas; Rubelt, Florian; Greiff, Victor & Pavlović, Milena [Show all 32 contributors for this article] (2021). The Future of Blood Testing Is the Immunome. Frontiers in Immunology. ISSN 1664-3224. 12:626793, p. 1–6. doi: 10.3389/fimmu.2021.626793. Full text in Research Archive
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Greiff, Victor & Sandve, Geir Kjetil Ferkingstad (2021). Profiling the baseline performance and limits of machine learning models for adaptive immune receptor repertoire classification . BioRxiv. ISSN 0362-4331.
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Greiff, Victor & Sandve, Geir Kjetil Ferkingstad (2021). immuneML: an ecosystem for machine learning analysis of adaptive immune receptor repertoires. BioRxiv. ISSN 0362-4331.
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Greiff, Victor & Sandve, Geir Kjetil Ferkingstad (2021). In silico proof of principle of machine learning-based antibody design at unconstrained scale . BioRxiv. ISSN 0362-4331.
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Greiff, Victor & Sandve, Geir Kjetil Ferkingstad (2021). One billion synthetic 3D-antibody-antigen complexes enable unconstrained machine-learning formalized investigation of antibody specificity prediction . BioRxiv. ISSN 0362-4331. doi: 10.1101/2021.07.06.451258.
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Akbar, Rahmad; Robert, Philippe Paul Auguste; Pavlović, Milena; Jeliazkov, Jeliazko R.; Snapkov, Igor & Slabodkin, Andrei [Show all 15 contributors for this article] (2021). A compact vocabulary of paratope-epitope interactions enables predictability of antibody-antigen binding. Cell reports. ISSN 2211-1247. 34:108856(11), p. 1–21. doi: 10.1016/j.celrep.2021.108856. Full text in Research Archive
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Laustsen, Andreas H.; Greiff, Victor; Karatt-Vellatt, Aneesh; Muyldermans, Serge & Jenkins, Timothy P. (2021). Animal Immunization, in Vitro Display Technologies, and Machine Learning for Antibody Discovery. Trends in Biotechnology. ISSN 0167-7799. 39(12), p. 1263–1273. doi: 10.1016/j.tibtech.2021.03.003. Full text in Research Archive
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Riedel, René; Addo, Richard; Ferreira-Gomes, Marta; Heinz, Gitta Anne; Heinrich, Frederik & Kummer, Jannis [Show all 33 contributors for this article] (2020). Discrete populations of isotype-switched memory B lymphocytes are maintained in murine spleen and bone marrow. Nature Communications. ISSN 2041-1723. 11(1). doi: 10.1038/s41467-020-16464-6.
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Fallet, Bénédict; Hao, Yi; Florova, Marianna; Cornille, Karen; de los Aires, Alba Verge & Girelli Zubani, Giulia [Show all 15 contributors for this article] (2020). Chronic viral infection promotes efficient germinal center B cell responses. Cell reports. ISSN 2211-1247. 30(4), p. 1013–1026. doi: 10.1016/j.celrep.2019.12.023. Full text in Research Archive
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Kräutler, Nike Julia; Yermanos, Alexander; Pedrioli, Alessandro; Welten, Suzanne P.M.; Lorgé, Dominique & Greczmiel, Ute [Show all 16 contributors for this article] (2020). Quantitative and Qualitative Analysis of Humoral Immunity Reveals Continued and Personalized Evolution in Chronic Viral Infection. Cell reports. ISSN 2211-1247. 30(4), p. 997–1012. doi: 10.1016/j.celrep.2019.12.088. Full text in Research Archive
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Yermanos, Alexander; Kräutler, Nike Julia; Pedrioli, Alessandro; Menzel, Ulrike; Greiff, Victor & Stadler, Tanja [Show all 8 contributors for this article] (2020). IgM Antibody Repertoire Fingerprints in Mice Are Personalized but Robust to Viral Infection Status. Frontiers in Cellular and Infection Microbiology. ISSN 2235-2988. 10:254, p. 1–13. doi: 10.3389/fcimb.2020.00254. Full text in Research Archive
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Yermanos, Alexander; Dounas, Andreas; Greiff, Victor; Stadler, Tanja; Oxenius, Annette & Reddy, Sai T. (2020). Inter- and intraspecies comparison of phylogenetic fingerprints and sequence diversity of immunoglobulin variable genes. Immunogenetics. ISSN 0093-7711. 72(5), p. 279–294. doi: 10.1007/s00251-020-01164-8. Full text in Research Archive
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Amoriello, Roberta; Greiff, Victor; Aldinucci, Alessandra; Bonechi, Elena; Carnasciali, Alberto & Peruzzi, Benedetta [Show all 12 contributors for this article] (2020). The TCR Repertoire Reconstitution in Multiple Sclerosis: Comparing One-Shot and Continuous Immunosuppressive Therapies. Frontiers in Immunology. ISSN 1664-3224. 11:559, p. 1–19. doi: 10.3389/fimmu.2020.00559. Full text in Research Archive
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Li, Hai; Limenitakis, Julien P.; Greiff, Victor; Yilmaz, Bahtiyar; Schären, Olivier & Urbaniak, Camilla [Show all 15 contributors for this article] (2020). Mucosal or systemic microbiota exposures shape the B cell repertoire. Nature. ISSN 0028-0836. 584(7820), p. 274–278. doi: 10.1038/s41586-020-2564-6. Full text in Research Archive
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Greiff, Victor; Yaari, Gur & Cowell, Lindsay G. (2020). Mining adaptive immune receptor repertoires for biological and clinical information using machine learning. Current Opinion in Systems Biology. ISSN 2452-3100. 24, p. 109–119. doi: 10.1016/j.coisb.2020.10.010.
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Smakaj, Erand; Babrak, Lmar; Ohlin, Mats; Shugay, Mikhail; Briney, Bryan & Tosoni, Deniz [Show all 16 contributors for this article] (2020). Benchmarking immunoinformatic tools for the analysis of antibody repertoire sequences. Bioinformatics. ISSN 1367-4803. 36(6), p. 1731–1739. doi: 10.1093/bioinformatics/btz845. Full text in Research Archive
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Weber, Cédric R.; Akbar, Rahmad; Yermanos, Alexander; Pavlovic, Milena; Snapkov, Igor & Sandve, Geir Kjetil [Show all 8 contributors for this article] (2020). immuneSIM: tunable multi-feature simulation of B- and T-cell receptor repertoires for immunoinformatics benchmarking. Bioinformatics. ISSN 1367-4803. 36(11), p. 3594–3596. doi: 10.1093/bioinformatics/btaa158. Full text in Research Archive
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Bartolomé Casado, Raquel; Landsverk, Ole J. B.; Chauhan, Sudhir Kumar; Richter, Lisa Maria; Phung, Danh & Greiff, Victor [Show all 18 contributors for this article] (2019). Resident memory CD8 T cells persist for years in human small intestine. Journal of Experimental Medicine (JEM). ISSN 0022-1007. 216(10), p. 2412–2426. doi: 10.1084/jem.20190414. Full text in Research Archive
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Miho, Enkelejda; Roskar, Rok; Greiff, Victor & Reddy, Sai T. (2019). Large-scale network analysis reveals the sequence space architecture of antibody repertoires. Nature Communications. ISSN 2041-1723. 10(1). doi: 10.1038/s41467-019-09278-8. Full text in Research Archive
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Tomescu-Baciu, Alina; Johansen, Jorunn; Holmøy, Trygve; Greiff, Victor; Stensland, Maria & De Souza, Gustavo Antonio [Show all 8 contributors for this article] (2019). Persistence of intrathecal oligoclonal B cells and IgG in multiple sclerosis. Journal of Neuroimmunology. ISSN 0165-5728. 333:576966, p. 1–7. doi: 10.1016/j.jneuroim.2019.576966. Full text in Research Archive
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Brown, Alex; Snapkov, Igor; Akbar, Rahmad; Pavlovic, Milena; Miho, Enkelejda & Sandve, Geir Kjetil [Show all 7 contributors for this article] (2019). Augmenting adaptive immunity: progress and challenges in the quantitative engineering and analysis of adaptive immune receptor repertoires. Molecular Systems Design & Engineering. ISSN 2058-9689. 4(4), p. 701–736. doi: 10.1039/c9me00071b.
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Ohlin, Mats; Scheepers, Cathrine; Corcoran, Martin; Lees, William D.; Busse, Christian E. & Bagnara, Davide [Show all 25 contributors for this article] (2019). Inferred allelic variants of immunoglobulin receptor genes: A system for their evaluation, documentation, and naming. Frontiers in Immunology. ISSN 1664-3224. 10:435, p. 1–13. doi: 10.3389/fimmu.2019.00435. Full text in Research Archive
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Mason, Derek M; Weber, Cédric R.; Parola, Cristina; Meng, Simon M; Greiff, Victor & Kelton, William [Show all 7 contributors for this article] (2018). High-throughput antibody engineering in mammalian cells by CRISPR/Cas9-mediated homology-directed mutagenesis. Nucleic Acids Research (NAR). ISSN 0305-1048. 46(14), p. 7436–7449. doi: 10.1093/nar/gky550.
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Miho, Enkelejda; Yermanos, Alexander; Weber, Cédric R.; Berger, Christoph T; Reddy, Sai T. & Greiff, Victor (2018). Computational Strategies for Dissecting the High-Dimensional Complexity of Adaptive Immune Repertoires. Frontiers in Immunology. ISSN 1664-3224. 9: 224, p. 1–15. doi: 10.3389/fimmu.2018.00224. Full text in Research Archive
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Yermanos, Alexander; Greiff, Victor; Krautler, Nike Julia; Menzel, Ulrike; Dounas, Andreas & Miho, Enkelejda [Show all 9 contributors for this article] (2017). Comparison of methods for phylogenetic B-cell lineage inference using time-resolved antibody repertoire simulations (AbSim) . Bioinformatics. ISSN 1367-4803. doi: 10.1093/bioinformatics/btx533.
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Huang, Yu-Ning; Peng, Kerui; Popejoy, Alice B.; Hu, Jieting; Nowicki, Theodore Scott & Gold, Stefan M. [Show all 13 contributors for this article] (2021). Ancestral diversity is limited in published T cell receptor sequencing studies. Immunity. ISSN 1074-7613. 54(10), p. 2177–2179. doi: 10.1016/j.immuni.2021.09.015.
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Greiff, Victor (2021). Development of Machine Learning Methods for the Analysis, Prediction and Generation of Antibody Repertoires.
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Greiff, Victor (2021). Machine-learning-based design of antibody therapeutics.
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Greiff, Victor (2021). Latest techniques in validation of computational drug discovery.
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Greiff, Victor (2021). Computational and machine learning approaches for identifying antigen-specific information in adaptive immune receptor repertoires.
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Greiff, Victor (2021). Quantifying the specificity of adaptive immunity.
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Greiff, Victor (2021). Introduction to computational adaptive immune receptor repertoire (AIRR) immunogenomics.
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Greiff, Victor (2021). Future perspectives: from protein structure to function.
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Greiff, Victor (2021). Steps in data processing and analysis of adaptive immune receptor repertoires: best practices, pitfalls, and future directions.
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Greiff, Victor (2021). Mining the rules of adaptive immune repertoires in health and disease.
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Greiff, Victor (2021). Quantifying the specificity of adaptive immunity.
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Greiff, Victor (2021). Quantifying the specificity of adaptive immunity.
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Widrich, Michael; Schäfl, Bernhard; Pavlović, Milena; Ramsauer, Hubert; Gruber, Lukas & Holzleitner, Markus [Show all 11 contributors for this article] (2020). Modern Hopfield Networks and Attention for Immune Repertoire Classification. Show summary
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Greiff, Victor (2020). Systems immunology of adaptive immune receptor repertoires: Deciphering immunological variation and specificity.
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Greiff, Victor (2020). Deep-learning based prediction of antibody-antigen interaction.
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Greiff, Victor (2020). Machine learning on sequence and structural adaptive immune receptor repertoire (AIRR) data .
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Greiff, Victor (2020). Quantifying the specificity of the adaptive immune response on the repertoire and sequence level.
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Greiff, Victor (2020). Systems immunology of immune receptor repertoires: Deciphering immunological specificity.
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Greiff, Victor (2020). Methods for mining the adaptive immune repertoire for SARS-CoV-2 diagnostics and therapeutics.
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Chain, Benny; Greiff, Victor; Textor, Johannes & Yaari, Gur (2019). Editorial: Methods and Applications of Computational Immunology. Frontiers in Immunology. ISSN 1664-3224. 10. doi: 10.3389/fimmu.2019.02818.
Published Jan. 2, 2018 3:34 PM
- Last modified Nov. 22, 2018 7:41 PM