Publications

Here you will find an overview of our research group's selected publications over several years.

Tretbar US, Rurik JG, Rustad EH, Sürün D, Köhl U, Olweus J, Buchholz F, Ivics Z, Fricke S & Blache U. Non-viral vectors for chimeric antigen receptor immunotherapy. Nat Rev Methods Primers 4, 74 (2024).
Giannakopoulou E, Lehander M, Virding Culleton S, Yang W, Li Y, Karpanen T, Yoshizato T, Rustad EH, Nielsen MM, Bollineni RC, Tran TT, Delic-Sarac M, Gjerdingen TJ, Douvlataniotis K, Laos M, Ali M, Hillen A, Mazzi S, Chin DWL, Mehta A, Holm JS, Bentzen AK, Bill M, Griffioen M, Gedde-Dahl T et al. (2023). A T cell receptor targeting a recurrent driver mutation in FLT3 mediates elimination of primary human acute myeloid leukemia in vivo. Nat Cancer, 4 (10), 1474-1490
Foldvari Z, Knetter C, Yang W, Gjerdingen TJ, Bollineni RC, Tran TT, Lund-Johansen F, Kolstad A, Drousch K, Klopfleisch R, Leisegang M, Olweus J (2023).
A systematic safety pipeline for selection of T-cell receptors to enter clinical use.
NPJ Vaccines, 8 (1), 126
Meyer S, Blaas I, Bollineni RC, Delic-Sarac M, Tran TT, Knetter C, Dai KZ, Madssen TS, Vaage JT, Gustavsen A, Yang W, Nissen-Meyer LSH, Douvlataniotis K, Laos M, Nielsen MM, Thiede B, Søraas A, Lund-Johansen F, Rustad EH, Olweus J (2023). Prevalent and immunodominant CD8 T cell epitopes are conserved in SARS-CoV-2 variants. Cell Rep, 42 (1), 111995
Ali, M., Giannakopoulou, E., Li, Y. et al. T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes. Nat Biotechnol (2021).
Ali M, Foldvari Z, Giannakopoulou E, Böschen ML, Strønen E, Yang W, Toebes M, Schubert B, Kohlbacher O, Schumacher TN, Olweus J. Induction Of Neoantigen Reactive T Cells From Healthy Donors. Nature Protocols (2019) 14, 1926-1943.
Strønen E, Toebes M, Kelderman S, van Buuren MM, Yang W, van Rooij N, Donia M, Böschen ML, Lund-Johansen F, Olweus J*, Schumacher TN*. Targeting of cancer neoantigens with donor-derived T cell receptor repertoires. Science (2016) 352 (6291), 1337-1341 *Shared senior and corresponding authors.
Liaskou E, Klemsdal Henriksen EK, Holm K, Kaveh F, Hamm D, Fear J, Viken MK, Hov JR, Melum E, Robins H, Olweus J*, Karlsen TH, Hirschfield GM*. High-throughput T-cell receptor sequencing across chronic liver diseases reveals distinct disease-associated repertoires. Hepatology 63, 1608-1619 (2016) *Corresponding author.
Kolstad A, Kumari S, Walczak M, Madsbu U, Hagtvedt T, Bogsrud TV, Kvalheim G, Holte H, Aurlien E, Delabie J, Tierens A, Olweus J. Sequential intranodal immunotherapy induces antitumor immunity and correlated regression of disseminated follicular lymphoma. Blood (2015);125:82-89.
Olweus J. Manufacture of CAR-T cells in the body. News and Views article
Nat Biotechnol. (2017) Jun 7;35(6):520-521.
Mensali N, Ying F, Sheng VO, Yang W, Walseng E, Kumari S, Fallang LE, Kolstad A, Uckert W, Malmberg KJ, Walchli S, Olweus J. Targeting B-cell neoplasia with T-cell receptors recognizing a CD20-derived peptide on patient-specific HLA. Oncoimmunology. (2016) Feb 18;5(5):e1138199.
Taraldsrud E, Fevang B, Jorgensen SF, Moltu K, Hilden V, Tasken K, Aukrust P, Myklebust JH, Olweus J. Defective IL-4 signaling in T cells defines severe common variable immunodeficiency. J Autoimmun (2017) Jul;81:110-119.
Kumari S, Walchli S, Fallang LE, Yang W, Lund-Johansen F, Schumacher TN, Olweus J. Alloreactive cytotoxic T cells provide means to decipher the immunopeptidome and reveal a plethora of tumor-associated self-epitopes. Proc Natl Acad Sci U S A 111, 403-408 (2014).
Abrahamsen IW, Stronen E, Wälchli S, Johansen JN, Kjellevoll S, Kumari S, Komada M, Gaudernack G, Tjonnfjord G, Toebes M, Schumacher TN, Lund-Johansen F, Olweus J.
Targeting B cell leukemia with highly specific allogeneic T cells with a public recognition motif. Leukemia. (2010) Nov;24(11):1901-9.
Kvale EØ, Dalgaard J, Lund-Johansen F, Rollag H, Farkas L, Midtvedt K, Jahnsen FL, Brinchmann JE, Olweus J. Plasmacytoid DCs regulate recall responses by rapid induction of IL-10 in memory T cells.
Blood, 109 (8), 3369-76
doi: 10.1182/blood-2006-06-031484
Ali, M., Giannakopoulou, E., Li, Y. et al. T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes. Nat Biotechnol 40, 488–498 (2022).

Published Oct. 14, 2019 1:43 PM - Last modified Aug. 21, 2025 1:05 PM