About the group

The research group includes all employees in the Department for Pediatric Neurology who are investigating topics within pediatric neurology and social pediatrics.

NervOUS aims to promote research on all pediatric neurological issues. We believe that collaboration and motivation through a shared platform can contribute to a healthy and inspiring research environment and lead to more PhDs in the field of pediatric neurology.

Projects

We have a number of large projects, including several national and international multi-centre studies.

Ongoing PhD projects

  • De-novo mutations in epilepsy-related disorders. Ida Stenshorne
  • Neurodevelopmental outcomes and the effect of nutrition in extremely preterm infants. Gunnthorunn Gunnarsdottir
  • Early weight trajectory, treatment outcomes and self-reported health in childhood and adolescents with obesity in Oslo, Norway. Sara M Shah
  • Nor-SMA. The safety and efficacy of nusinersen in Norwegian pediatric patients with Spinal muscular atropy (SMA). Merete Wik-Klokk

Research projects

  • COREpABI (COgnitive REhabilitation pediatric Aquired Brain Injury)

For more projects, see our Norwegian webpage.

Multi-centre studies

  • SSADHD: “Natural History Study of Patients with Succinic Semialdehyde Dehydrogenase Deficiency”
  • A Single-Stage, Adaptive, Open-label, Dose Escalation Safety and Efficacy Study of AADC Deficiency in Pediatric Patients (AADC)
  • FENOMENA- Immunophenotypic study of complex diseases as ME/CFS and narcolepsia type 1

For more studies, please see our Norwegian webpage.

Cooperation

We cooperate with a number of national and international partners. Our internaitonal partners include:

  • Karolinska Institutet, Stockholm og Drottning Silvias Barn-och Ungdomssjukhus, Gøteborg
  • Københavns Universitet
  • Duke University, North Carolina
  • Erasmus MC University Medical Center Rotterdam
  • University Medical Center Groningen
  • Evelina London Children’s Hospital
  • Queen's University, Kingston, Canada
  • Manchester Metropolitan University, Manchester, UK

Selected publications

  • Dahl et al. “Unmet health care needs over the first 2 years after pediatric traumaticbrain injury». Eur J Paediatr Neurol 2024;49: 73-81.
  • Wik-klokk et al. «Type 1 spinal muscular atrophy treated with nusinersen in Norway, a five-year follow-up.” Eur J Paediatr Neurol 2024;53:109-116.
  • Kirschner J... Wallace S C, Servais L et al “2024 update: European consensus statement on gene therapy for spinal muscular atrophy”. Eur J Paediatr Neurol. 2024 Jul;51:73-78
  • Yildiz Y… Oppebøen M, Opladen T et al. «Levodopa-refractory hyperprolactinemia and pituitary findings in inherited disorders of biogenic amine metabolism” J Inherit Metab Dis 2024: May; 47 (3); 431-446
  • Stenshorne I… Ramm-Pettersen, Henriksen MW et al. «Impact of genetic testing in developmental and epileptic encephalopathy-patients” Epilepsy Behav. 2024 Dec 21;163:110174
  • Hikmat O… Rasmussen M, Brodtkorb E et al. «Status epilepticus in POLG disease: a large multinational study”. J Neurol 2024;271:5156-5164
  • Kristensen E... Rasmussen M, Tangeraas T et al. «Epidemiology and natural history of POLG disease in Norway: a nationwide cohort study” Ann Clin Trans Neurol 2024;11:1819-1830.