Computer tomography (CT), Nuclear medicine techniques (NM) and magnetic resonance imaging (MRI) is presently the mainstay of imaging diagnosis for many neurological diseases. Advanced MRI techniques have especially contributed to improved diagnostic brain imaging of degenerative, inflammatory, vascular and neoplastic diseases.

Oslo University Hospital has comprehensive clinical activity in the field of central nervous system disorders, and many group members already participate in interdisciplinary teams together with neurosurgeons, neurologists, oncologists, and other clinicians. Many of the members of this research group has existing international research collaborations.

Longterm goals

The main aim of this group is to gather active researchers, PhD students and other research-interested colleagues from the Department of Radiology and Nuclear Medicine at Oslo University Hospital.

We also invite colleagues from other hospitals in our region. By learning about the projects that are currently ongoing within our group there will be a potential for new collaborations. Also new research ideas may evolve from such meetings.

Thus, we will stimulate new research collaborations and projects through getting to know each other and each other’s projects better. This way knowledge and ideas from the members of the group can contribute to new research questions and future projects

Projects

  • IMPROVISED-MS (Improved visualization and detection of chronic active lesions with quantitative susceptibility mapping in Multiple Sclerosis)
  • The MSDIR study
  • KG Jebsen Center for Brain Fluid Research (UiO/OUS): K.G. Jebsen Centre for Brain Fluid research.
  • AI-supported diagnosis of intracranial hemorrhage (qER): Kunstig intelligens i radiologisk vurdering. (in Norwegian)
  • NorCOAST: The Norwegian Cognitive Impairment After Stroke (Nor-COAST) study.
  • COBRA: (The effects of Covid-19 on brain health in the Norwegian NeuroCOVID study).
  • Human Brain Clearance Imaging (HBCI) (EU-funded international research consortium, 2022-2025): Development of non-invasive techniques for imaging of brain clearance function.
  • A machine learning approach for the prediction of cognitive impairment after stroke” (funded by Nasjonalforeningen for folkehelse).
  • IMPRESS-Imaging perfusion restrictions from extracellular solid stress.
  • ImNUT-study. Impact of early nutritional intake on preterm brain: A MRI study.

Cooperation

  • Prof. Thijs van Osch, Leiden University Medical Centre, NL,C.J. Gorter MRI Center.
  • Dr. Farhaan Vahidy, TIRR Memorial, Houston, TX, USA / Houston Methodist Hospital, Houston, TX, USA
  • Pascal Spincemaille, Well Cornell, USA
  • Aziz M. Ulug, San Diego, USA
  • Henk-Jan Mutsaerts. Amsterdam UMC  

Selected publications

  1. Understanding Pediatric Neuroimmune Disorder Conflicts: A Neuroradiologic Approach in the Molecular Era. Andres Server Alonso, Tomas Sakinis, Helle Cecilie V. Pfeiffer, Inger Sandvig, Jon Barlinn, and Pål B. Marthinsen. RadioGraphics 2020 40:5, 1395-1411.
  2. Eva B. Aamodt, Dag Alnæs, Ann-Marie G. de Lange, Stina Aam, Till Schellhorn, Ingvild Saltvedt, Mona K. Beyer, Lars T. Westlye. Longitudinal brain age prediction and cognitive function after stroke, Neurobiology of Aging, Volume 122, 2023.
  3. Prysiazhniuk Y, Server A, Leske H, Bech-Aase Ø, Helseth E, Eijgelaar RS, Fuster-García E, Brandal P, Bjørnerud A, Otáhal J, Petr J, Nordhøy W. Diffuse glioma molecular profiling with arterial spin labeling and dynamic susceptibility contrast perfusion MRI: A comparative study. Neurooncol Adv. 2024.
  4. Eide PK, Vinje V, Pripp AH, Mardal KA, Ringstad G. Sleep deprivation impairs molecular clearance from the human brain. Brain. 2021.
  5. Böker T, Vanem TT, Pripp AH, Rand-Hendriksen S, Paus B, Smith HJ, Lundby R. Dural ectasia in Marfan syndrome and other hereditary connective tissue disorders: a 10-year follow-up study. Spine J. 2019.
  6. Eide PK, Ringstad G. Functional analysis of the human perivascular subarachnoid space. Nat Commun. 2024.