Anne Gjøen Simonsen

Professor - Autophagy
Image of Anne Gjøen Simonsen
Norwegian version of this page
Phone +47 22851110
Mobile phone +47-99350960
Room 3174
Username
Visiting address Sognsvannsveien 9 Domus Medica 3. etasje 0317 Oslo
Postal address Postboks 1112 Blindern 0317 Oslo
Other affiliations Institute for Cancer Research

Other affiliations

Department of Molecular Medicine

Institute for Cancer Research, Oslo University Hospital


Academic interests

  • Intracellular membrane trafficking
  • The molecular mechanisms of autophagy
  • Role of autophagy in disease (cancer and neurodegeneration)

Courses taught

Background

Education

  • Dr. Scient (PhD), University of Oslo (UiO), 1996, Molecular Cell Biology
  • Cand.Scient (MSc), UiO, 1992. Cell Biology

Positions

  • 2011-present: Professor, Division of Biochemistry, Dept. of Molecular Medicine, Institute of Basic Medical Sciences (IMB), UiO
  • 2015-2016: Head of Department of Molecular Medicine, IMB, UiO
  • 2013-2014: Deputy head of Institute, IMB, UiO
  • 2009-2010: Associate professor, Dept. of Biochemistry, Institute of Basic Medical Sciences, UiO
  • 2007-2009: Associate professor II, Institute for Molecular Biosciences, UiO
  • 2005-2009: Senior Scientist and project leader, Dept. of Biochemistry, the Norwegian Radium Hospital
  • 2004-2005: visiting scientist Cellular Neurobiology Laboratory, Salk institute for Biological Studies, CA
  • 2002-2003: Senior Scientist and Project leader, Dept. of Immunosystems, Dynal Biotech ASA
  • 1996-2001, 2004: Postdoc fellow, Dept. of Biochemistry, the Norwegian Radium Hospital

Awards

  • King Olav Vs Cancer Research prize (2019)
  • Elected member of the Norwegian Academy of Sciences
  • Ragnar Mørk’s legacy prize 2007

 

Tags: Cancer, Cell biology, Membrane trafficking, Autophagy, Neurodegenerative disease, Life science

Publications

  • Sporbeck, Katharina; Haas, Maximilian L.; Pastor-Maldonado, Carmen J.; Schüssele, David S.; Hunter, Catherine & Takacs, Zsuzsanna [Show all 18 contributors for this article] (2023). The ABL-MYC axis controls WIPI1-enhanced autophagy in lifespan extension. Communications Biology. ISSN 2399-3642. 6(1). doi: 10.1038/s42003-023-05236-9. Full text in Research Archive
  • Kaur, Namrita; de la Ballina, Laura R; Haukaas, Håvard Styrkestad; Torgersen, Maria Lyngaas; Radulovic, Maja & Munson, Michael J [Show all 11 contributors for this article] (2023). TECPR1 is activated by damage-induced sphingomyelin exposure to mediate noncanonical autophagy. EMBO Journal. ISSN 0261-4189. 42(17), p. 1–19. doi: 10.15252/embj.2022113105. Full text in Research Archive
  • Sikkeland, Jørgen; Ng, Matthew; Nenseth, Hatice Zeynep; Ünal, Bilal; Qu, Su & Jin, Yang [Show all 8 contributors for this article] (2022). STAMP2 suppresses autophagy in prostate cancer cells by modulating the integrated stress response pathway. American Journal of Cancer Research. ISSN 2156-6976. 12(1), p. 327–336. Full text in Research Archive
  • Rahman, Mohummad Aminur; Engelsen, Agnete ; Sarowar, Shahin; Bindesbøll, Christian; Birkeland, Even & Goplen, Dorota [Show all 10 contributors for this article] (2022). Bortezomib abrogates temozolomide-induced autophagic flux through an ATG5 dependent pathway. Frontiers in Cell and Developmental Biology. ISSN 2296-634X. 10, p. 1–23. doi: 10.3389/fcell.2022.1022191. Full text in Research Archive
  • Charsou, Chara; Ng, Matthew & Simonsen, Anne Gjøen (2022). Regulation of autophagosome biogenesis and mitochondrial bioenergetics by the cholesterol transport protein GRAMD1C. Autophagy. ISSN 1554-8627. doi: 10.1080/15548627.2022.2155020.
  • Ganley, Ian G. & Simonsen, Anne Gjøen (2022). Diversity of mitophagy pathways at a glance. Journal of Cell Science. ISSN 0021-9533. 135(23), p. 1–8. doi: 10.1242/jcs.259748. Full text in Research Archive
  • Ng, Matthew; Charsou, Chara; Da Silva Lapao, Ana Sofia; Singh, Sakshi; Trachsel Moncho, Laura Cristina & Schultz, Sebastian Wolfgang [Show all 9 contributors for this article] (2022). The cholesterol transport protein GRAMD1C regulates autophagy initiation and mitochondrial bioenergetics. Nature Communications. ISSN 2041-1723. 13(1). doi: 10.1038/s41467-022-33933-2. Full text in Research Archive
  • Maestro, Inés; de la Ballina, Laura R; Porras, Gracia; Corrochano, Silvia; de Lago, Eva & Simonsen, Anne Gjøen [Show all 8 contributors for this article] (2022). Discovery of Mitophagy Inhibitors with Therapeutic Potential in Different Familial Amyotrophic Lateral Sclerosis Mutations. International Journal of Molecular Sciences. ISSN 1661-6596. 23(20). doi: 10.3390/ijms232012676. Full text in Research Archive
  • Cable, Jennifer; Weber-Ban, Eilika; Clausen, Tim; Walters, Kylie J.; Sharon, Michal & Finley, Daniel J. [Show all 32 contributors for this article] (2022). Targeted protein degradation: from small molecules to complex organelles—a Keystone Symposia report. Annals of the New York Academy of Sciences. ISSN 0077-8923. 1510(1), p. 79–99. doi: 10.1111/nyas.14745.
  • Xu, Jing; Yang, Kevin C; Go, Nancy Erro; Colborne, Shane; Ho, Cally J & Hosseini-Beheshti, Elham [Show all 11 contributors for this article] (2022). Chloroquine treatment induces secretion of autophagy-related proteins and inclusion of Atg8-family proteins in distinct extracellular vesicle populations. Autophagy. ISSN 1554-8627. 18(11), p. 2547–2560. doi: 10.1080/15548627.2022.2039535. Full text in Research Archive
  • Simonsen, Anne Gjøen & Wollert, Thomas (2022). Don't forget to be picky – selective autophagy of protein aggregates in neurodegenerative diseases. Current Opinion in Cell Biology. ISSN 0955-0674. 75, p. 1–7. doi: 10.1016/j.ceb.2022.01.009. Full text in Research Archive
  • Søreng, Kristiane; Pankiv, Serhiy; Bergsmark, Camilla; Haugsten, Ellen Margrethe; Dahl, Anette Kathinka & de la Ballina, Laura R [Show all 9 contributors for this article] (2022). ALFY localizes to early endosomes and cellular protrusions to facilitate directional cell migration . Journal of Cell Science. ISSN 0021-9533. 135(4). doi: 10.1242/jcs.259138. Full text in Research Archive
  • Munson, Michael Joseph; Mathai, Benan John; Ng, Matthew; Trachsel Moncho, Laura Cristina; de la Ballina, Laura R & Simonsen, Anne Gjøen (2022). GAK and PRKCD kinases regulate basal mitophagy. Autophagy. ISSN 1554-8627. 18(2), p. 467–469. doi: 10.1080/15548627.2021.2015154. Full text in Research Archive
  • Terešak, Petra; Da Silva Lapao, Ana Sofia; Subic, Nemanja; Boya, Patricia; Elazar, Zvulun & Simonsen, Anne Gjøen (2021). Regulation of PRKN-independent mitophagy. Autophagy. ISSN 1554-8627. 18(1), p. 24–39. doi: 10.1080/15548627.2021.1888244.
  • Corkery, Dale P.; Nadeem, Aftab; Aung, Kyaw Min; Hassan, Ahmed; Liu, Tao & Cervantes-Rivera, Ramón [Show all 14 contributors for this article] (2021). Vibrio cholerae cytotoxin MakA induces noncanonical autophagy resulting in the spatial inhibition of canonical autophagy. Journal of Cell Science. ISSN 0021-9533. 134(5). doi: 10.1242/jcs.252015.
  • Kumar, Suresh; Javed, Ruheena; Mudd, Michal H.; Pallikkuth, Sandeep; Lidke, Keith A. & Jain, Ashish [Show all 22 contributors for this article] (2021). Mammalian hybrid pre-autophagosomal structure HyPAS generates autophagosomes. Cell. ISSN 0092-8674. 184(24), p. 5950–5969. doi: 10.1016/j.cell.2021.10.017.
  • Ng, Matthew; Wai, Timothy & Simonsen, Anne Gjøen (2021). Quality control of the mitochondrion. Developmental Cell. ISSN 1534-5807. 56(7), p. 881–905. doi: 10.1016/j.devcel.2021.02.009.
  • Durgan, Joanne; Lystad, Alf Håkon Lohsen; Sloan, Katherine; Carlsson, Sven R.; Wilson, Michael I. & Marcassa, Elena [Show all 14 contributors for this article] (2021). Non-canonical autophagy drives alternative ATG8 conjugation to phosphatidylserine. Molecular Cell. ISSN 1097-2765. 81(9), p. 2031–2040.e8. doi: 10.1016/j.molcel.2021.03.020. Full text in Research Archive
  • Klionsky, Daniel J.; Petroni, Giulia; Amaravadi, Ravi K; Baehrecke, Eric H; Ballabio, Andrea & Boya, Patricia [Show all 59 contributors for this article] (2021). Autophagy in major human diseases. EMBO Journal. ISSN 0261-4189. 40. doi: 10.15252/embj.2021108863. Full text in Research Archive
  • Maestro, Inés; de la Ballina, Laura R; Simonsen, Anne Gjøen; Boya, Patricia & Martinez, Ana (2021). Phenotypic Assay Leads to Discovery of Mitophagy Inducers with Therapeutic Potential for Parkinson's Disease. ACS Chemical Neuroscience. ISSN 1948-7193. 12(24), p. 4512–4523. doi: 10.1021/acschemneuro.1c00529. Full text in Research Archive
  • Sharma, Kulbhushan; Asp, Nagham Theres; Harrison, Sean; Siller, Richard; Baumgarten, Saphira Felicitas & Gupta, Swapnil [Show all 10 contributors for this article] (2021). Autophagy modulates cell fate decisions during lineage commitment. Autophagy. ISSN 1554-8627. p. 1–17. doi: 10.1080/15548627.2021.2008691. Full text in Research Archive
  • Giovannucci, Tatiana A.; Salomons, Florian A.; Stoy, Henriette; Herzog, Laura K.; Xu, Shanshan & Qian, Weixing [Show all 15 contributors for this article] (2021). Identification of a novel compound that simultaneously impairs the ubiquitin-proteasome system and autophagy. Autophagy. ISSN 1554-8627. doi: 10.1080/15548627.2021.1988359. Full text in Research Archive
  • Munson, Michael Joseph; Mathai, Benan J.; Ng, Matthew; Trachsel Moncho, Laura Cristina; de la Ballina, Laura R & Schultz, Sebastian W. [Show all 13 contributors for this article] (2021). GAK and PRKCD are positive regulators of PRKN-independent mitophagy. Nature Communications. ISSN 2041-1723. 12(1). doi: 10.1038/s41467-021-26331-7. Full text in Research Archive
  • Bindesbøll, Christian; Aas, Aleksander; Ogmundsdottir, Margret Helga; Pankiv, Serhiy; Reine, Trine M. & Zoncu, Roberto [Show all 7 contributors for this article] (2020). NBEAL1 controls SREBP2 processing and cholesterol metabolism and is a susceptibility locus for coronary artery disease. Scientific Reports. ISSN 2045-2322. 10(1). doi: 10.1038/s41598-020-61352-0. Full text in Research Archive
  • Gawel, Kinga Aurelia; Turski, Waldemar A.; van der Ent, Wietske; Mathai, Benan John; Kirstein-Smardzewska, Karolina Joanna & Simonsen, Anne [Show all 7 contributors for this article] (2020). Phenotypic Characterization of Larval Zebrafish (Danio rerio) with Partial Knockdown of the cacna1a Gene. Molecular Neurobiology. ISSN 0893-7648. 57(4). doi: 10.1007/s12035-019-01860-x.
  • Lotsberg, Maria Lie; Wnuk-Lipinska, Katarzyna; Terry, Stéphane; Tan, Tuan Zea; Lu, Ning & Moncho, Laura Trachsel [Show all 26 contributors for this article] (2020). AXL Targeting Abrogates Autophagic Flux and Induces Immunogenic Cell Death in Drug-Resistant Cancer Cells. Journal of Thoracic Oncology. ISSN 1556-0864. 15(6), p. 973–999. doi: 10.1016/j.jtho.2020.01.015. Full text in Research Archive
  • Melia, Thomas; Lystad, Alf Håkon & Simonsen, Anne (2020). Autophagosome biogenesis: From membrane growth to closure. Journal of Cell Biology. ISSN 0021-9525. 219(6). doi: 10.1083/jcb.202002085. Full text in Research Archive
  • Moller, Katrin; Sigurbjornsdottir, Sara; Arnthorsson, Asgeir; Podenberg, Vivian; Dilshat, Ramile & Fock, Valerie [Show all 16 contributors for this article] (2019). MITF has a central role in regulating starvation-induced autophagy in melanoma. Scientific Reports. ISSN 2045-2322. 9. doi: 10.1038/s41598-018-37522-6. Full text in Research Archive
  • Lystad, Alf Håkon & Simonsen, Anne (2019). Mechanisms and Pathophysiological Roles of the ATG8 Conjugation Machinery. Cells. ISSN 2073-4409. 8(9). doi: 10.3390/cells8090973. Full text in Research Archive
  • Herzog, Laura K; Kevei, Eva; Marchante, Ricardo; Botther, Claudia; Bindesbøll, Christian & Lystad, Alf Håkon [Show all 12 contributors for this article] (2019). The Machado-Joseph disease deubiquitylase ataxin-3 interacts with LC3C/GABARAP and promotes autophagy. Aging Cell. ISSN 1474-9718. doi: 10.1111/acel.13051. Full text in Research Archive
  • Gawel, Kinga Aurelia; Turski, Waldemar A.; van der Ent, Wietske; Mathai, Benan John; Kirstein-Smardzewska, Karolina Joanna & Simonsen, Anne [Show all 7 contributors for this article] (2019). Phenotypic Characterization of Larval Zebrafish (Danio rerio) with Partial Knockdown of the cacna1a Gene . Molecular Neurobiology. ISSN 0893-7648. doi: 10.1007/s12035-019-01860-x. Full text in Research Archive
  • Herhaus, Lina; Bhaskara, Ramachandra M; Lystad, Alf Håkon; Gestal-Mato, Uxia; Covarrubias-Pinto, Adriana & Bonn, Florian [Show all 9 contributors for this article] (2019). TBK1-mediated phosphorylation of LC3C and GABARAP-L2 controls autophagosome shedding by ATG4 protease. EMBO Reports. ISSN 1469-221X. doi: 10.15252/embr.201948317. Full text in Research Archive
  • Zhen, Yan; Spangenberg, Helene; Munson, Michael Joseph; Brech, Andreas; Schink, Kay Oliver & Tan, Kia Wee [Show all 13 contributors for this article] (2019). ESCRT-mediated phagophore sealing during mitophagy. Autophagy. ISSN 1554-8627. p. 1–16. doi: 10.1080/15548627.2019.1639301. Full text in Research Archive
  • Rahman, Mohummad Aminur; Gras Navarro, Andrea; Brekke, Jorunn; Engelsen, Agnete; Bindesbøll, Christian & Sarowar, Shahin [Show all 16 contributors for this article] (2019). Bortezomib administered prior to temozolomide depletes MGMT, chemosensitizes glioblastoma with unmethylated MGMT promoter and prolongs animal survival. British Journal of Cancer. ISSN 0007-0920. 121, p. 545–555. doi: 10.1038/s41416-019-0551-1. Full text in Research Archive
  • Gras Navarro, Andrea; Espedal, Heidi; Vareecal Joseph, Justin; Moncho, Laura Trachsel; Bahador, Marzieh & Gjertsen, Bjørn Tore [Show all 12 contributors for this article] (2019). Pretreatment of glioblastoma with bortezomib potentiates natural killer cell cytotoxicity through TRAIL/DR5 mediated apoptosis and prolongs animal survival. Cancers. ISSN 2072-6694. 11:996(7), p. 1–25. doi: 10.3390/cancers11070996. Full text in Research Archive
  • Rodriguez de la Ballina, Laura; Munson, Michael Joseph & Simonsen, Anne (2019). Lipids and Lipid-Binding Proteins in Selective Autophagy. Journal of Molecular Biology (JMB). ISSN 0022-2836. p. 1–25. doi: 10.1016/j.jmb.2019.05.051. Full text in Research Archive
  • Chaurasia, Madhuri; Gupta, Swapnil; Das, Asmita; Dwarakanath, B. S.; Simonsen, Anne & Sharma, Kulbhushan (2019). Radiation induces EIF2AK3/PERK and ERN1/IRE1 mediated pro-survival autophagy. Autophagy. ISSN 1554-8627. 15(8), p. 1391–1406. doi: 10.1080/15548627.2019.1582973. Full text in Research Archive
  • Lystad, Alf Håkon; Carlsson, Sven R; Rodriguez de la Ballina, Laura; Kauffman, Karlina J; Nag, Shanta & Yoshimori, Tamotsu [Show all 8 contributors for this article] (2019). Distinct functions of ATG16L1 isoforms in membrane binding and LC3B lipidation in autophagy-related processes. Nature Cell Biology. ISSN 1465-7392. 21(3), p. 372–383. doi: 10.1038/s41556-019-0274-9. Full text in Research Archive
  • Abudu, Yakubu Princely; Pankiv, Serhiy; Mathai, Benan John; Lamark, Trond; Johansen, Terje & Simonsen, Anne (2019). NIPSNAP1 and NIPSNAP2 act as “eat me” signals to allow sustained recruitment of autophagy receptors during mitophagy. Autophagy. ISSN 1554-8627. doi: 10.1080/15548627.2019.1637642.
  • Abudu, Yakubu Princely; Pankiv, Serhiy; Mathai, Benan John; Lystad, Alf Håkon; Bindesbøll, Christian & Brenne, Hanne Britt [Show all 14 contributors for this article] (2019). NIPSNAP1 and NIPSNAP2 act as “eat-me signal” for mitophagy. Developmental Cell. ISSN 1534-5807. 49(4), p. 509–525.e12. doi: 10.1016/j.devcel.2019.03.013. Full text in Research Archive
  • Søreng, Kristiane; Neufeld, Thomas P & Simonsen, Anne (2018). Membrane Trafficking in Autophagy. International Review of Cell and Molecular Biology. ISSN 1937-6448. 336, p. 1–92. doi: 10.1016/bs.ircmb.2017.07.001.
  • Kraft, Claudine; Boya, Patricia; Codogno, Patrice; Elazar, Zvulun; Eskelinen, Eeva-Liisa & Farres, Judith [Show all 14 contributors for this article] (2018). Driving next-generation autophagy researchers towards translation (DRIVE), an international PhD training program on autophagy. Autophagy. ISSN 1554-8627. doi: 10.1080/15548627.2018.1515532. Full text in Research Archive
  • Søreng, Kristiane; Munson, Michael Joseph; Lamb, Christopher R.; Bjørndal, Gunnveig Toft; Pankiv, Serhiy & Carlsson, Sven R. [Show all 8 contributors for this article] (2018). SNX18 regulates ATG9A trafficking from recycling endosomes by recruiting Dynamin-2. EMBO Reports. ISSN 1469-221X. 19:e44837(4), p. 1–12. doi: 10.15252/embr.201744837. Full text in Research Archive
  • Johannessen, Tor-Christian Aase; Hasan-Olive, Md Mahdi; Zhu, Huaiyang; Denisova, Oxana V.; Grudic, Amra & Latif, Md Abdul [Show all 20 contributors for this article] (2018). Thioridazine inhibits autophagy and sensitizes glioblastoma cells to temozolomide. International Journal of Cancer. ISSN 0020-7136. 144(7), p. 1735–1745. doi: 10.1002/ijc.31912.
  • Ogmundsdottir, MH; Fock, Valerie; Sooman, L; Pogenberg, V; Dilshat, R & Bindesbøll, Christian [Show all 10 contributors for this article] (2018). A short isoform of ATG7 fails to lipidate LC3/GABARAP. Scientific Reports. ISSN 2045-2322. 8(1), p. 1–8. doi: 10.1038/s41598-018-32694-7. Full text in Research Archive
  • Skah, Seham; Richartz, Nina; Duthil, Eva; Gilljam, Karin Margaretha; Bindesbøll, Christian & Naderi, Elin Hallan [Show all 11 contributors for this article] (2018). cAMP-mediated autophagy inhibits DNA damage-induced death of leukemia cells independent of p53. OncoTarget. ISSN 1949-2553. 9(54), p. 30434–30449. doi: 10.18632/oncotarget.25758. Full text in Research Archive
  • Søreng, Kristiane; Knævelsrud, Helene; Holland, Petter & Simonsen, Anne (2017). HS1BP3 inhibits autophagy by regulation of PLD1. Autophagy. ISSN 1554-8627. 13(5), p. 985–986. doi: 10.1080/15548627.2017.1291483. Full text in Research Archive
  • Simonsen, Anne; Mathai, Benan John & Meijer, Annemarie (2017). Studying Autophagy in Zebrafish. Cells. ISSN 2073-4409. 6(3). doi: 10.3390/cells6030021. Full text in Research Archive
  • Schlafli, Anna M; Isakson, Pauline; Garattini, E; Simonsen, Anne & Tschan, Mario P (2017). The autophagy scaffold protein ALFY is critical for the granulocytic differentiation of AML cells. Scientific Reports. ISSN 2045-2322. 7(1). doi: 10.1038/s41598-017-12734-4. Full text in Research Archive
  • Kjos, Ingrid; Distefano, Marita Borg; Sætre, Frank Ove; Repnik, Urska; Holland, Petter & Jones, Arwyn T [Show all 10 contributors for this article] (2017). Rab7b modulates autophagic flux by interacting with Atg4B. EMBO Reports. ISSN 1469-221X. 18(10), p. 1727–1739. doi: 10.15252/embr.201744069. Full text in Research Archive
  • Galluzzi, Lorenzo; Baehrecke, Eric H.; Ballabio, Andrea; Boya, Patricia; Bravo-San Pedro, José Manuel & Cecconi, Francesco [Show all 54 contributors for this article] (2017). Molecular definitions of autophagy and related processes. EMBO Journal. ISSN 0261-4189. 36(13), p. 1811–1836. doi: 10.15252/embj.201796697.
  • Aas, Aleksander; Isakson, Pauline; Bindesbøll, Christian; Alemu, Endalkachew Ashenafi; Klungland, Arne & Simonsen, Anne (2017). Nucleocytoplasmic shuttling of FTO does not affect starvation-induced autophagy. PLOS ONE. ISSN 1932-6203. 12(3). doi: 10.1371/journal.pone.0168182. Full text in Research Archive
  • Holland, Petter; Knævelsrud, Helene; Søreng, Kristiane; Mathai, Benan John; Lystad, Alf Håkon & Pankiv, Serhiy [Show all 16 contributors for this article] (2016). HS1BP3 negatively regulates autophagy by modulation of phosphatidic acid levels. Nature Communications. ISSN 2041-1723. 7. doi: 10.1038/ncomms13889. Full text in Research Archive
  • Shatz, Oren; Holland, Petter; Elazar, Zuvlun & Simonsen, Anne (2016). Complex relations between phospholipids, autophagy, and neutral lipids. TIBS -Trends in Biochemical Sciences. Regular ed.. ISSN 0968-0004. 41(11), p. 907–923. doi: 10.1016/j.tibs.2016.08.001.
  • Dragich, Joanna M; Kuwajima, Takaaki; Hirose-Ikeda, Megumi; Yoon, Michael S; Eenjes, Evelien & Bosco, Joan R [Show all 18 contributors for this article] (2016). Autophagy linked FYVE (Alfy/WDFY3) is required for establishing neuronal connectivity in the mammalian brain. eLIFE. ISSN 2050-084X. 5(September). doi: 10.7554/eLife.14810.
  • Lystad, Alf Håkon & Simonsen, Anne (2016). Phosphoinositide-binding proteins in autophagy. FEBS Letters. ISSN 0014-5793. p. 2454–2468. doi: 10.1002/1873-3468.12286.
  • Andersen, Aram Nikolai; Landsverk, Ole J. B.; Simonsen, Anne; Bogen, Bjarne; Corthay, Alexandre & Øynebråten, Inger (2016). Coupling of HIV-1 antigen to the selective autophagy receptor SQSTM1/p62 promotes T-cell-mediated immunity. Frontiers in Immunology. ISSN 1664-3224. 7. doi: 10.3389/fimmu.2016.00167. Full text in Research Archive
  • Mamińska, Agnieszka; Bartosik, Anna; Banach-Orlowska, Magdalena; Pilecka, Iwona; Jastrzębski, Kamil & Zdżalik-Bielecka, Daria [Show all 19 contributors for this article] (2016). ESCRT proteins restrict constitutive NF-κB signaling by trafficking cytokine receptors. Science Signaling. ISSN 1945-0877. 9(411). doi: 10.1126/scisignal.aad0848.
  • Hieke, Nora; Löffler, Antje S.; Kaizuka, Takeshi; Berleth, Niklas; Böhler, Philip & Drießen, Stefan [Show all 18 contributors for this article] (2015). Expression of a ULK1/2 binding-deficient ATG13 variant can partially restore autophagic activity in ATG13-deficient cells. Autophagy. ISSN 1554-8627. 11(9), p. 1471–1483. doi: 10.1080/15548627.2015.1068488.
  • Drießen, Stefan; Berleth, Niklas; Friesen, Olena; Löffler, Antje S.; Böhler, Philip & Hieke, Nora [Show all 15 contributors for this article] (2015). Deubiquitinase inhibition by WP1130 leads to ULK1 aggregation and blockade of autophagy. Autophagy. ISSN 1554-8627. 11(9), p. 1458–1470. doi: 10.1080/15548627.2015.1067359.
  • Yla-Anttila, P; Mikkonen, E; Happonen, KE; Holland, Petter; Ueno, T & Simonsen, Anne [Show all 7 contributors for this article] (2015). RAB24 facilitates clearance of autophagic compartments during basal conditions. Autophagy. ISSN 1554-8627. 11(10), p. 1833–1848. doi: 10.1080/15548627.2015.1086522.
  • Holland, Petter & Simonsen, Anne (2015). Actin shapes the autophagosome. Nature Cell Biology. ISSN 1465-7392. 17(9), p. 1094–1096. doi: 10.1038/ncb3224.
  • Carlsson, Sven R & Simonsen, Anne (2015). Membrane dynamics in autophagosome biogenesis. Journal of Cell Science. ISSN 0021-9533. 128(2), p. 193–205. doi: 10.1242/jcs.141036.
  • Galluzzi, Lorenzo; Pietrocola, Federico; San-Pedro, Jose Manuel; Amaravadi, Ravi; Baehreck, Eric H & Cecconi, Francesco [Show all 24 contributors for this article] (2015). Autophagy in malignant transformation and cancer progression. EMBO Journal. ISSN 0261-4189. 34(7), p. 856–880. doi: 10.15252/embj.201490784.
  • Lystad, Alf Håkon & Simonsen, Anne (2015). Assays to monitor aggrephagy. Methods. ISSN 1046-2023. 75, p. 112–119. doi: 10.1016/j.ymeth.2014.12.019.
  • Eriksen, Agnete Bratsberg; Torgersen, Maria Lyngaas; Lillebø Holm, Kristine; Abrahamsen, Greger; Spurkland, Anne & Moskaug, Jan Øivind [Show all 8 contributors for this article] (2015). Retinoic acid-induced IgG Production in TLR-activated human primary B cells involves ULK1-mediated autophagy. Autophagy. ISSN 1554-8627. 11(3), p. 460–471. doi: 10.1080/15548627.2015.1009797.
  • Lystad, Alf Håkon; Ichimura, Yoshinobu; Takagi, K; Yang, Yinjie; Pankiv, Serhiy & Kanegae, Yumi [Show all 12 contributors for this article] (2014). Structural determinants in GABARAP required for the selective binding and recruitment of ALFY to LC3B-positive structures. EMBO Reports. ISSN 1469-221X. 15(5), p. 557–565. doi: 10.1002/embr.201338003.
  • Mandell, Michael A.; Jain, Ashish; Arko-Mensah, John; Chauhan, Santosh; Kimura, Tomonori & Dinkins, Christina [Show all 14 contributors for this article] (2014). TRIM Proteins Regulate Autophagy and Can Target Autophagic Substrates by Direct Recognition. Developmental Cell. ISSN 1534-5807. 30(4), p. 394–409. doi: 10.1016/j.devcel.2014.06.013.
  • Holland, Petter; Torgersen, Maria Lyngaas; Sandvig, Kirsten & Simonsen, Anne (2014). LYST affects lysosome size and quantity, but not trafficking or degradation through autophagy or endocytosis. Traffic: The moving front of cell biology. ISSN 1398-9219. 15(12), p. 1390–1405. doi: 10.1111/tra.12227.
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Published Apr. 13, 2011 2:40 PM - Last modified July 2, 2020 12:55 PM