Marianne Thoresen

Professor - Systems Physiology
Image of Marianne Thoresen
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Phone +47-22851568
Room 2366
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Visiting address Sognsvannsveien 9 Domus Medica 0372 OSLO
Postal address Postboks 1103 Blindern 0317 OSLO

Academic interests

  • Circulation Physiology:
    • newborn and adult cerebral circulation
    • skin circulation and thermoregulation
  • Protection of the newborn brain:
    • animal models of brain injury
    • experimental and clinical trials of neuroprotection
    • therapeutic hypothermia and xenon

Background

  • 1998-2011 Consultant Neonatologist and Professor in Neonatal N Neuroscience, St Michaels Hospital and University of Bristol, UK
  • 1997 Consultant  Neonatologist,Ullevaal University Hospital, Oslo
  • 1996-98 Visiting Professor (Swedish Res Council) Inst of Physiology, University of Gothenburg, Sweden
  • 1995-7 Training position Pediatrics/neonatology, Ullevaal UH , Oslo
  • 1993-95 Visiting Scientist The Bloomsbury Magnetic Resonance unit, University College Hospital, London
  • 1992-94 Carreer research award, Norwegian Research Council, Inst for Exp Med Research, Ullevaal UH, Oslo
  • 1988-92 1995-97 Training position Pediatrics/neonatology, Ullevaal UH and the National Center for Epilepsy, Oslo
  • 1986-88 Post doc (NFR) The Nobel Institute for Neurophysiology, Karolinska Institute, Stockholm, Sweden
  • 1985-86 Post doc (NFR) Ullevaal UH, Oslo
  • 1984-85 Turnus kandidat Elverum
  • 1982-83 Locum Senior Lecturer in Physiology, Inst of Physiology, UiO
  • 1975-82 Medical School UiO with 1978 as full time student researcher (physiology)
  • 1972-75 Physiotherapy work and Examen Philosophicum  UiO 1974
  • 1970-72  Oslo Physiotherapy School
  • State School education in Horten 1958-70

Awards

  • 2011: The Vice Chancellors Impact award for 2011 University of Bristol
  • 2010: Elected member of Academia Europaea
  • 2007: Elected member of the Norwegian Academy of Science and Letters
  • 2007: The Tooley lecturerer, University of San Fransisco
  • 2005: The Peter Tizard lecturerer, The Neonatal Society, United Kindom

Positions held

  • Member on steering commeettee for Randomised Controlled Trial of hypothermia during echmo treatment in neonates (The NEST trial, UK)
  • Member of data monitoring commette for RCT of cooling after perinatal asphyxia (The ICE trial, Australia) 
  • 2008-2014: Specialist advisor for National Institute for Health and Clinical Excellence (NICE) UK
  • 2009- Editorial Board Therapeutic Hypothermia and Temperature Management

Collaborations

  • Professor of Anaesthesiology John Dingley, University  Department of Anaestehsiology, University of Swansea, UK
  • Dr Xun Liu, PhD, The Neonatal Neuroscience lab, University of Bristol, UK
  • Professor Henrik Hagberg, Physiology and Obstetrics, University of Gothenburg, Sweden
  • Professor of Physiology and Pediatrcis Alistar Gunn, University of Auckland,NZ
  • Professor of Neonatal Medicine, Drude Fugelseth, Oslo University Hospitals, section Ullevaal, Oslo 
  • Professor of  Anestesiology, Petter Andreas Steen, Universitetet of Oslo, Oslo University hospitals ,section Ullevaal, Oslo
Tags: Newborn, Organ physiology, Oxygen deprivation, Lack of oxygen, Therapeutic hypothermia and xenon inhalation, Body temperature, Peripheral circulation and cardiac function

Publications

  • Thoresen, Marianne; Falck, Mari; Osredkar, Damjan; Flatebo, Torun; Maes, Elke; Wood, Thomas Ragnar & Sabir, Hemmen (2017). Hypothermic Neuronal Rescue from Infection-sensitised Hypoxic-ischaemic Rescue from Infection-sensitised Hypoxic-ischaemiuc Brain injury is Pathogen Dependent. International Journal of Developmental Neuroscience.  ISSN 0736-5748. . doi: 10.1159/000455838
  • Thoresen, Marianne; Gunn, A J; Robertson, Nicola J; Laptook, Abbot R; Barks, J D; Wassink, Guido & Bennet, Laura (2017). Therapeutic hypothermia translates from ancient history in to practice. Pediatric Research.  ISSN 0031-3998.  81(1-2), s 202- 209 . doi: 10.1038/pr.2016.198
  • Thoresen, Marianne; Skranes, Janne Helen; Løhaugen, Gro; Wood, Thomas Ragnar; Schumacher, Eva Margrethe; Fugelseth, Drude; Osredkar, Damjan; SERVER, ANDRES; Stiris, Tom & Cowan, Frances (2017). Amplitude-Integrated Electroencephalography Improves the Identification of Infants with Encephalopathy for Therapeutic Hypothermia and Predicts Neurodevelopmental Outcomes at 2 Years of Age. The Internet Journal of Pediatrics and Neonatology.  ISSN 1528-8374. . doi: 10.1016/j.peds.2017.04.041 Full text in Research Archive
  • Thoresen, Marianne; Wood, Thomas Ragnar; Falck, Mari & Hodds, C (2017). Rectal temperature in the first five hours after hypoxia-ischaemia critically affetcs neuropathological outcomes in neonatale rats. Pediatric Research.  ISSN 0031-3998. . doi: 10.1038/pr2017.51
  • Elstad, Maja; Liu, Xun & Thoresen, Marianne (2016). Heart rate response to therapeutic hypothermia in infants with hypoxic–ischaemic encephalopathy. Resuscitation.  ISSN 0300-9572.  106, s 53- 57 . doi: 10.1016/j.resuscitation.2016.06.023
  • Hemmen, Sabir; Wood, Thomas Ragnar; Gill, Hannah; Liu, Xun; Dingley, John & Thoresen, Marianne (2016). Xenon depresses aEEG background voltage activity whilst maintaining cardiovascular stability in sedated healthy newborn pigs . Journal of the Neurological Sciences.  ISSN 0022-510X.  363, s 140- 144 . doi: 10.1016/j.jns.2016.02.051 Full text in Research Archive
  • Kochanek, P; Kitagawa, RS; Batchelor, P & Thoresen, Marianne (2016). Central Nervous System Injury and Temperature Management. Therapeutic Hypothermia and Temperature Management.  ISSN 2153-7658.  6(3), s 112- 115 . doi: 10.1089/ther.2016.29014.pjk
  • Sabir, Hemmen; Osredkar, Damjan; Maes, Elke; Wood, Thomas Ragnar & Thoresen, Marianne (2016). Xenon combined with therapeutic hypothermia is not neuroprotective after severe hypoxia-ischemia in neonatal rats. PLoS ONE.  ISSN 1932-6203.  11(6) . doi: 10.1371/journal.pone.0156759
  • Thoresen, Marianne; Gunn, Alistair J; Laptook, Abbot R & Barks, J (2016). Therapeutic hypothermia translates from ancient history, into practice. Pediatric Research.  ISSN 0031-3998.
  • Wood, Thomas Ragnar; Osredkar, Damjan; Puchades, Maja Amedjkouh; Maes, Elke; Falck, Mari; Flatebø, Torun; Walløe, Lars; Sabir, Hemmen & Thoresen, Marianne (2016). Treatment temperature and insult severity influence the neuroprotective effects of therapeutic hypothermia. Scientific Reports.  ISSN 2045-2322.  6 . doi: 10.1038/srep23430 Full text in Research Archive
  • Wood, Thomas Ragnar; Smit, Elisa; Maes, Elke; Osredkar, Damjan; Falck, Mari; Elstad, Maja & Thoresen, Marianne (2016). Monitoring of cerebral blood flow during hypoxia-ischemia and resuscitation in the neonatal rat using laser speckle imaging. Physiological Reports.  ISSN 2051-817X.  4(7), s 1- 14 . doi: 10.14814/phy2.12749 Full text in Research Archive
  • Aquilina, Kristian & Thoresen, Marianne (2015). A newborn piglet survival model of post-hemorrhagic ventricular dilatation, In Jerome Y. Yager (ed.),  Animal Models of Neurodevelopmental Disorders.  Humana Press.  ISBN 978-1-4939-2708-1.  [Foreløpig ukjent].
  • Chakkarapani, Elavazhagan & Thoresen, Marianne (2015). The Newborn Pig Global Hypoxic-Ischemic Model of Perinatal Brain and Organ Injury, In Jerome Y. Yager (ed.),  Animal Models of Neurodevelopmental Disorders.  Humana Press.  ISBN 978-1-4939-2708-1.  [Foreløpig ukjent].
  • Dingley, John; Liu, Xun; Gill, Hannah; Smit, Elisa; Sabir, Hemmen; Tooley, James; Chakkarapani, Ela; Windsor, David & Thoresen, Marianne (2015). The feasibility of using a portable xenon delivery device to permit earlier xenon ventilation with therapeutic cooling of neonates during ambulance retrieval. Anesthesia and Analgesia.  ISSN 0003-2999.  120(6), s 1331- 1336 . doi: 10.1213/ANE.0000000000000693
  • Gunn, Alistair J & Thoresen, Marianne (2015). Animal studies of neonatal hypothermic neuroprotection have translated well in to practice. Resuscitation.  ISSN 0300-9572.  97, s 88- 90 . doi: 10.1016/j.resuscitation.2015.03.026
  • Hoque, Nicholas; Liu, Xun; Chakkarapani, Elavazhagan & Thoresen, Marianne (2015). Minimal systemic hypothermia combined with selective head cooling evaluated in a pig model of hypoxia-ischemia. Pediatric Research.  ISSN 0031-3998.  77(5), s 674- 680 . doi: 10.1038/pr.2015.31
  • Jary, Sally; Smit, Elisa; Liu, Xun; Cowan, Frances & Thoresen, Marianne (2015). Less severe cerebral palsy outcomes in infants treated with therapeutic hypothermia. Acta Paediatrica.  ISSN 0803-5253.  104(12), s 1241- 1247 . doi: 10.1111/apa.13146
  • Liu, Xun; Dingley, John; Scull-Brown, Emma & Thoresen, Marianne (2015). Adding 5 hours delayed xenon to delayed hypothermia treatment improves long term function in neonatal rats surviving to adulthood. Pediatric Research.  ISSN 0031-3998.  77, s 779- 783 . doi: 10.1038/pr.2015.49
  • Osredkar, Damjan; Sabir, Hemmen; Falck, Mari; Wood, Thomas Ragnar; Maes, Elke; Flatebø, Torun; Puchades, Maja Amedjkouh & Thoresen, Marianne (2015). Hypothermia Does Not Reverse Cellular Responses Caused by Lipopolysaccharide in Neonatal Hypoxic-Ischaemic Brain Injury. Developmental Neuroscience.  ISSN 0378-5866.  37(4-5), s 390- 397 . doi: 10.1159/000430860
  • Skranes, Janne Helen; Cowan, Frances; Stiris, Tom; Fugelseth, Drude; Thoresen, Marianne & SERVER, ANDRES (2015). Brain imaging in cooled encephalopathic neonates does not differ between four and 11 days after birth. Acta Paediatrica.  ISSN 0803-5253.  104(8), s 752- 758 . doi: 10.1111/apa.13016
  • Smit, Elisa; Liu, Xun; Gill, Hannah; Jary, Sally; Wood, Thomas Ragnar & Thoresen, Marianne (2015). The effect of resuscitation in 100% oxygen on brain injury in a newborn rat model of severe hypoxic-ischaemic encephalopathy. Resuscitation.  ISSN 0300-9572.  96, s 214- 219 . doi: 10.1016/j.resuscitation.2015.07.050
  • Smit, Elisa; Liu, Xun; Jary, Sally; Cowan, Frances & Thoresen, Marianne (2015). Cooling neonates who do not fulfil the standard cooling criteria - short and long term outcomes. Acta Paediatrica.  ISSN 0803-5253.  104(2), s 138- 145 . doi: 10.1111/apa.12784
  • Thoresen, Marianne (2015). Who should we cool after perinatal asphyxia?. Seminars in Fetal & Neonatal Medicine.  ISSN 1744-165X.  20(2), s 66- 71 . doi: 10.1016/j.siny.2015.01.002
  • Thoresen, Marianne & Sabir, Hemmen (2015). Epilepsy: Neonatal seizures still lack safe and effective treatment. Nature Reviews Neurology.  ISSN 1759-4758.  11(6), s 311- 312 . doi: 10.1038/nrneurol.2015.74
  • Whitelaw, Andrew; Osredkar, Damjan & Thoresen, Marianne (2015). Neurological & Neuromuscular Disorders, In Mhairi G. MacDonald & Mary M. K. Seshia (ed.),  Avery's Neonatology: Pathophysiology and Management of the Newborn (Seventh Edition).  Lippincott Williams & Wilkins.  ISBN 9781451192681.  46.  s 994 - 1016
  • Wood, Thomas Ragnar & Thoresen, Marianne (2015). Physiological responses to hypothermia . Seminars in Fetal & Neonatal Medicine.  ISSN 1744-165X.  20(2), s 87- 96 . doi: 10.1016/j.siny.2014.10.005
  • Azzopardi, D.; Strohm, B; Marlow, N; Brocklehurst, P; Halliday, H; Juszczak, E; Kapellou, O; Levene, Malcolm; Thoresen, Marianne; Tusor, N; Whitelaw, A & Edwards, D (2014). Effects of hypothermia for perinatal asphyxia on childhood outcomes – The TOBY Children Study. New England Journal of Medicine.  ISSN 0028-4793. . doi: 10.1056/NEJMoa1315788
  • Chakkarapani, Ela; Davis, Jonathan & Thoresen, Marianne (2014). Therapeutic hypothermia delays the C-reactive protein response and suppresses white blood cell and platelet count in infants with neonatal encephalopathy. Archives of Disease in Childhood: Fetal and Neonatal Edition.  ISSN 1359-2998.  99(6), s F458- F463 . doi: 10.1136/archdischild-2013-305763
  • Curtis, DJ; Thoresen, Marianne & Case, CP (2014). Secretions from placenta, after hypoxia/reoxygenation, can damage developing neurones of brain under experimental conditions. Experimental Neurology.  ISSN 0014-4886. . doi: 10.1016/j.expneurol.2014.05.003
  • Dingley, John; Tooley, James; Liu, Xun; Scull-Brown, Emma; Elstad, Maja; Chakkarapani, Elavazhagan; Sabir, Hemmen & Thoresen, Marianne (2014). Xenon Ventilation During Therapeutic Hypothermia in Neonatal Encephalopathy: A Feasibility Study. Pediatrics.  ISSN 0031-4005.  133(5), s 809- 818 . doi: 10.1542/peds.2013-0787
  • Elstad, Maja; Walløe, Lars; Holme, Nathalie; Maes, Elke & Thoresen, Marianne (2014). Respiratory sinus arrhythmia stabilizes mean arterial blood pressure at high-frequency interval in healthy humans . European Journal of Applied Physiology.  ISSN 1439-6319.  115(3), s 521- 530 . doi: 10.1007/s00421-014-3042-3
  • Gill, Hannah; Thoresen, Marianne; Bishop, Sarah; Smit, Elisa; Liu, Xun; Walløe, Lars & Dingley, John (2014). Equipotent subanesthetic concentrations of sevoflurane and xenon preventing cold-stimulated vocalization of neonatal rats. Anesthesiology.  ISSN 0003-3022.  121(6), s 1194- 1202
  • Hannah, Gill; Thoresen, Marianne; Smit, Elisa; Davis, Jonathan; Liu, Xun; Dingley, John & Elstad, Maja (2014). Sedation management during therapeutic hypothermia for neonatal encephalopathy: Atropine premedication for endotracheal intubation causes a prolonged increase in heart rate. Resuscitation.  ISSN 0300-9572.  85(10), s 1394- 1398 . doi: 10.1016/j.resuscitation.2014.07.002
  • Hoque, Nicholas; Sabir, Hemmen; Maes, Elke; Bishop, Sarah & Thoresen, Marianne (2014). Validation of a neuropathology score using quantitative methods to evaluate brain injury in a pig model of hypoxia ischaemia. Journal of Neuroscience Methods.  ISSN 0165-0270.  230, s 30- 36 . doi: 10.1016/j.jneumeth.2014.04.005
  • Osmond, E; Billetop, A; Jary, Sally; Likeman, M; Thoresen, Marianne & Luyt, Karen (2014). Neonatal seizures: magnetic resonance imaging adds value in the diagnosis and prediction of neurodisability. Acta Paediatrica.  ISSN 0803-5253. . doi: 10.1111/apa.12583
  • Osredkar, Damjan; Thoresen, Marianne; Maes, Elke; Flatebø, Torun; Elstad, Maja & Sabir, Hemmen (2014). Hypothermia is not neuroprotective after infection-sensitized neonatal hypoxic-ischemic brain injury. Resuscitation.  ISSN 0300-9572.  85(4), s 567- 572 . doi: 10.1016/j.resuscitation.2013.12.006
  • Sabir, Hemmen; Walløe, Lars; Dingley, John; Smit, Elisa; Li, Xun & Thoresen, Marianne (2014). Combined treatment of Xenon and Hypothermia in Newborn Rats - Additive or Synergistic Effect?. PLoS ONE.  ISSN 1932-6203.  9(10) . doi: 10.1371/journal.pone.0109845
  • Skranes, Janne Helen; Elstad, Maja; Thoresen, Marianne; Cowan, Frances; Stiris, Tom & Fugelseth, Drude (2014). Hypothermia Makes Cerebral Resistance Index a Poor Prognostic Tool in Encephalopathic Newborns. Neonatology.  ISSN 1661-7800.  106(1), s 17- 23 . doi: 10.1159/000358229
  • Smit, Elisa & Thoresen, Marianne (2014). Xenon as a neuroprotective treatment in neonatal encephalopathy. Infant.  ISSN 1745-1205.  10(1), s 1- 4
  • Chakkarapani, Ela & Thoresen, Marianne (2013). Brain and whole body cooling, In MacDonald Mhairi G. & Ramasethu Jayashree (ed.),  Atlas of Procedures in Neonatology.  Lippincott Williams & Wilkins.  ISBN 9781451144109.  Chapter.
  • Chakkarapani, Elavazhagan; Dingley, John; Aquilina, Kristian; Osredkar, Damjan; Liu, Xun & Thoresen, Marianne (2013). Effects of xenon and hypothermia on cerebrovascular pressure reactivity in newborn global hypoxic–ischemic pig model. Journal of Cerebral Blood Flow and Metabolism.  ISSN 0271-678X.  33(11), s 1752- 1760 . doi: 10.1038/jcbfm.2013.123
  • Field, D; Juszczak, E; Linsell, L; Azzopardi, D.; Thoresen, Marianne; Cowan, F; Marlow, N & Edwards, D (2013). Neonatal ECMO study of temperature (NEST): a randomized controlled trial. Pediatrics.  ISSN 0031-4005. . doi: 10.1542/peds.2013-1754
  • Jary, Sally; Walløe, Lars; Whitelaw, Andrew & Thoresen, Marianne (2013). Comparison of Bayley-2 and Bayley-3 scores at 18 months in term infants following neonatal encephalopathy and therapeutic hypothermia. Developmental Medicine & Child Neurology.  ISSN 0012-1622.  55(11), s 1053- 1059 . doi: 10.1111/dmcn.12208
  • Liu, X; Dingley, John; Elstad, Maja; Brown, EL; Steen, Petter Andreas & Thoresen, Marianne (2013). Minimum Alveolar Concentration (MAC) for Sevoflurane and Xenon at Normothermia and Hypothermia in newborn pigs. Acta Anaesthesiologica Scandinavica.  ISSN 0001-5172. . doi: 10.1111/aas.12055
  • Liu, Xun; Chakkarapani, Ela; Stone, J & Thoresen, Marianne (2013). Effect of cardiac compressions and hypothermia treatment on cardiac troponin I in newborns with perinatal asphyxia. Resuscitation.  ISSN 0300-9572. . doi: 10.1016/j.resuscitation.2013.07.003
  • Sabir, Hemmen; Bishop, Sarah; Cohen, Nicki; Maes, Elke; Liu, Xun; Dingley, John & Thoresen, Marianne (2013). Neither Xenon nor Fentanyl Induce Apoptosis in the newborn pig brain. Anesthesiology.  ISSN 0003-3022.  119(2), s 345- 357

View all works in Cristin

  • Chakkarapani, Ela & Thoresen, Marianne (2016). C-Reactive Protein Response in Infants Cooled for Neonatal Encephalopathy Is Delayed in Females More Than Males.
  • Falck, Mari; Maes, Elke; Flatebo, Torun; Wood, Thomas Ragnar; Sabir, Hemmen; Osredkar, Damjan & Thoresen, Marianne (2016). Gram-positive Septicemia Sensitises The Neonatal Brain To Hypoxic-ischemic Injury, Without Inhibiting The Neuroprotective Effect Of Hypothermia.
  • Lee-Kelland, Richard; Dingley, John; Okano, S; Scull-Brown, Emma; Thoresen, Marianne & Chakkarapani, Ela (2016). Xenon as Neuroprotection: A Demonstration of an Automated Delivery System.
  • Smit, Elisa; Wood, Thomas Ragnar; Elstad, Maja; Liu, Xun & Thoresen, Marianne (2016). The effect of resuscitation in 100% Oxygen on cerebral blood flow and neuropathology in a newborn rat model of hypoxia-ischaemia.
  • Steinsland, Tonje & Thoresen, Marianne (2016, 20. november). Vårt lille land : 'Cooling babies' . [TV].
  • Thoresen, Marianne (2016). Cooling the right children with the optimal protocol using valid short and long term outcome examinations - are we getting any better?.
  • Thoresen, Marianne (2016). Hypothermia and beyond. (Perinatal Asphyxia).
  • Thoresen, Marianne (2016). Xenon and hypothermia in neonates.
  • Thoresen, Marianne; Basu, S K; Kaiser, J R; Guffey, D; Minard, C G; Guillet, Ronnie & Gunn, A J (2016). Hypoglycaemia and hyperglycaemia are associated with unfavourable outcome in infants with hypoxic ischaemic encephalopathy: a post hoc analysis of the CoolCap Study. Archives of Disease in Childhood: Fetal and Neonatal Edition.  ISSN 1359-2998.  s 149- 155 . doi: 10.1136/archdischild-2015-308733
  • Thoresen, Marianne & Herefordshire & Worcester, BBC Radio (2016, 19. august). Interview following-up on progress of a baby who had been enrolled in a clinical trial. [Radio].
  • Wood, Thomas Ragnar; Skranes, Janne Helen; Falck, Mari; Lohaugen, GC; Stiris, Tom; Loberg, EM; Fugelseth, Drude & Thoresen, Marianne (2016). Core Temperature After Neonatal Hypoxia-Ischaemia Predicts Long-term Cerebral Injury.
  • Chakkarapani, Ela; Aquilina, Julian; Lee-Kelland, Richard; Jary, Sally; Liu, Xun & Thoresen, Marianne (2015). Morphine exposure and neurodevelopment outcome in cooled neonatal encephalopathy infants with mild cerebral dysfunction.
  • Falck, Mari; Osredkar, Damjan; Maes, Elke; Wood, Thomas Ragnar; Puchades, Maja Amedjkouh; Sabir, Hemmen & Thoresen, Marianne (2015). Systemic Inflammation Negates Hypothermic Neuroprotection in a Neonatal HIE-model.
  • Falck, Mari; Osredkar, Damjan & Thoresen, Marianne (2015). Hypothermia does not reverse cellular responses caused by lipopolysaccharide in neonatal hypoxic ischemic brain injury.
  • Lee-Kelland, Richard; Chakkarapani, Ela; Jary, Sally; Liu, Xun & Thoresen, Marianne (2015). Temperature Instability Post Rewarming in Neonates Who Have Received Therapeutic Hypothermia.
  • Sabir, Hemmen; Maes, Elke; Liu, Xun; Dingley, John & Thoresen, Marianne (2015). Fentanyl induces cerebellar internal granular cell layer apoptosis in healthy newborn pigs.
  • Sabir, Hemmen; Osredkar, Damjan; Maes, Elke; Wood, Thomas Ragnar & Thoresen, Marianne (2015). Therapeutic Hypothermia Combined With Inhaled Xenon in Newborn Rats: the Ongoing Challenge following severe hypoxicischemic brain injury.
  • Thoresen, Marianne (2015). Editorial: Cooling after perinatal asphyxia. Seminars in Fetal & Neonatal Medicine.  ISSN 1744-165X.  20(2) . doi: 10.1016/j.siny.2015.01.003
  • Thoresen, Marianne (2015). Hypothermia after perinatal asphyxia; do we select and cool the right babies with the optimal cooling protocol and follow up agreements?.
  • Thoresen, Marianne (2015). Optimal hypothermia treatment: an update from experimental and clinical research.
  • Thoresen, Marianne (2015). Optimal resuscitation followed by optimal hypothermia with and without added xenon inhalation.
  • Thoresen, Marianne (2015). Who should we cool, for how long and at what temperature?.
  • Thoresen, Marianne; Chakkarapani, Ela; Walløe, Lars; Løberg, Else Marit; Maes, Elke; Liu, Xun & Osredkar, Damjan (2015). No cardiac protection from hypothermia or xenon inhalation after hypoxia-ischemia in newborn pigs.
  • Wood, Thomas Ragnar; Osredkar, Damjan; Flatebø, Torun; Falck, Mari; Maes, Elke & Thoresen, Marianne (2015). Temperature Dependence Of Hypothermic Neuroprotection In A R Model Of Neonatal Hypoxic Ischaemic Encephalopathy.
  • Wood, Thomas Ragnar; Osredkar, Damjan; Flatebø, Torun; Falck, Mari; Maes, Elke & Thoresen, Marianne (2015). Temperature Dependence Of Hypothermic Neuroprotection in a Rat Model of Neonatal Hypoxic Ischaemic Enchephopathy.
  • Davis, Jonathan; Liu, Xun; Gill, Hannah; Smit, Elisa; Chakkarapani, Ela & Thoresen, Marianne (2014). Inclusion Benefit for Neonates in the Control Arm of a Randomized Controlled Trial of Xenon With Cooling.
  • Gill, Hannah; Thoresen, Marianne; Smit, Elisa; Davis, Jonathan; Liu, Xun; Dingley, John & Elstad, Maja (2014). Is Atropine Before Intubation of Term Neonates Justified? An Observation from the CoolXe2 Trial.
  • Jary, Sally; Liu, Xun & Thoresen, Marianne (2014). Severity of Cerebral Palsy Is Reduced in Cooled Infants.
  • Liu, Xun; de Vries, Linda s; Hellström-Westas, Lena & Thoresen, Marianne (2014). Seizure Severity and Outcome in Cooled and Non-Cooled Asphyxiated Infants.
  • Liu, Xun; Osredkar, Damjan; Jary, Sally; Chakkarapani, Ela & Thoresen, Marianne (2014). Cooling Reduces Late Seizures Disorder in Infants After Perinatal Asphyxia.
  • Osredkar, Damjan; Thoresen, Marianne; Maes, Elke; Flatebo, Torun; Elstad, Maja & Sabir, Hemmen (2014). Hypothermia Is Not Neuroprotective after Infection-Sensitized Neonatal Hypoxic-Ischemic Brain Injury.
  • Sabir, Hemmen; Walløe, Lars; Dingley, John; Chakkarapani, Ela; Smit, Elisa; Bishop, Sarah; Liu, Xun & Thoresen, Marianne (2014). The Neuroprotective Effects of Xenon and Therapeutic Hypothermia Are Not Synergistic after Hypoxia-Ischaemia in Newborn Rats.
  • Skranes, Janne Helen; Cowan, Frances; Stiris, Tom; Fugelseth, Drude; Thoresen, Marianne & SERVER, ANDRES (2014). Cerebral MRI on Days 4 and 11 in Encephalopathic Neonates Treated With Hypothermia.
  • Smit, Elisa; Gill, Hannah & Thoresen, Marianne (2014). Letter in response to ‘Stridor in Asphyxiated Neonates Undergoing Therapeutic Hypothermia’ by Orme et al. Pediatrics.  ISSN 0031-4005. . doi: 10.1542/peds.2013-2053
  • Smit, Elisa; Jary, Sally; Liu, Xun; Cowan, Frances & Thoresen, Marianne (2014). Cooling Infants Outside the Standard Criteria - Short and Long Term Outcomes.
  • Thoresen, Marianne (2014, 09. november). Her kjøles den nyfødte jenta ned til 33,5 grader . [TV].  TV 2 Nyhetene.
  • Thoresen, Marianne (2014, 09. november). Hun står bak metoden som redder tusenvis av barn fra hjerneskade . [Internett].  TV 2, Nyheter, Innenriks.
  • Thoresen, Marianne (2014, 10. november). Intervju om nedkjøling av nyfødte . [TV].  God Morgen Norge, TV 2.
  • Thoresen, Marianne (2014, 10. november). Intervju om nedkjøling av nyfødte . [TV].  TV 2 Nyhetskanalen.
  • Thoresen, Marianne (2014, 25. februar). Professor: – Xenon kan være livsfarlig . [TV].  TV 2 Nyhetene.
  • Thoresen, Marianne (2014). The David Hardy Lecture - Neuroprotection: Past, present and future.
  • Thoresen, Marianne & Whitelaw, Andrew (2014). (‘Utility of Animal Research’): - Animal research has been essential to saving babies’ lives. BMJ (British Medical Journal).  ISSN 0959-8146.  348, s g4174- g4174 . doi: http://dx.doi.org/10.1136/bmj.g4174
  • Wood, Thomas Ragnar; Osredkar, Damjan; Sabir, Hemmen; Falck, Mari; Maes, Elke & Thoresen, Marianne (2014). Cooler Isn't Better – Hypothermia at Three Different Temperatures Does Not Provide Neuroprotection in a Rat Model of Severe Neonatal Hypoxic-Ischaemic Encephalopathy.
  • Chakkarapani, Ela; Liu, Xun & Thoresen, Marianne (2013). Postnatal Course of C-Reactive Protein in Relation to Therapeutic Hypothermia and Neurodevelopment Outcome in Term Infants with Perinatal Asphyxial Encephalopathy.
  • Elstad, Maja; Walløe, Lars; Holme, Nathalie; Maes, Elke & Thoresen, Marianne (2013). Respiratory sinus arrhythmia stabilises mean arterial blood pressure.
  • Elstad, Maja; Walløe, Lars; Holme, Nathalie; Maes, Elke & Thoresen, Marianne (2013). Respiratory sinus arrhythmia stabilises mean arterial blood pressure in healthy humans.
  • Gill, Hannah; Dingley, John; Smit, Elisa; Liu, Xun; Osredkar, Damjan; Sabir, Hemmen & Thoresen, Marianne (2013). 50% Xenon Significantly Reduces aEEG Background Activity in Healthy Newborn Pigs.
  • Gill, Hannah; Smit, Elisa; Liu, Xun; Sabir, Hemmen; Thoresen, Marianne & Dingley, John (2013). Automated Xenon and Oxygen Delivery with CO2 Removal in a Neonate Using a single-Use Closed Breathing Circuit and Three Standard Ventilators.
  • Holme, Nathalie; Rein, Erling Bekkestad; Walloe, Lars; Thoresen, Marianne & Elstad, Maja (2013). Cardiac stroke volume predicts progressive central hypovolemia by three different non-invasive methods. The FASEB Journal.  ISSN 0892-6638.  27
  • Holme, Nathalie; Rein, Erling Bekkestad; Walløe, Lars; Thoresen, Marianne & Elstad, Maja (2013). Cardiac stroke volume predicts progressive central hypovolemia by three different non-invasive methods.
  • Jary, Sally; Whitelaw, Andrew; Walløe, Lars & Thoresen, Marianne (2013). Bayley-3 Requires a Change in the Definition of Severe Disability: Implications for Neuroprotection Research.
  • Karlsson, Mathias & Thoresen, Marianne (2013). S100B in Urine from Newborn Pigs Subjected to 45 Minutes of Global Hypoxia Ischemia: A Method Comparison.
  • Osredkar, Damjan; Belič, Aleš; Koritnik, Blaž; Neubauer, David & Thoresen, Marianne (2013). Predictive value of computer assisted electroencephalography analysis in infants with infantile spasms.
  • Sabir, Hemmen; Bishop, Sarah; Cohen, Nicki; Maes, Elke; Liu, Xun; Dingley, John & Thoresen, Marianne (2013). Xenon and Fentanyl Do Not Induce Neuroapoptis in the Newborn Pig Brain – Isoflurane Does.

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Published Apr. 13, 2011 2:41 PM - Last modified Dec. 19, 2011 5:49 PM