Marianne Thoresen

Professor - Systems Physiology
Image of Marianne Thoresen
Norwegian version of this page
Phone +47 22851568
Room 2366
Visiting address Sognsvannsveien 9 Domus Medica 0372 Oslo
Postal address Postboks 1103 Blindern 0317 Oslo

Academic interests

  • Circulation Physiology:
    • newborn and adult cerebral circulation
    • skin circulation and thermoregulation
  • Protection of the newborn brain:
    • animal models of brain injury
    • experimental and clinical trials of neuroprotection
    • therapeutic hypothermia and xenon


  • 1998-2011 Consultant Neonatologist and Professor in Neonatal N Neuroscience, St Michaels Hospital and University of Bristol, UK
  • 1997 Consultant  Neonatologist,Ullevaal University Hospital, Oslo
  • 1996-98 Visiting Professor (Swedish Res Council) Inst of Physiology, University of Gothenburg, Sweden
  • 1995-7 Training position Pediatrics/neonatology, Ullevaal UH , Oslo
  • 1993-95 Visiting Scientist The Bloomsbury Magnetic Resonance unit, University College Hospital, London
  • 1992-94 Carreer research award, Norwegian Research Council, Inst for Exp Med Research, Ullevaal UH, Oslo
  • 1988-92 1995-97 Training position Pediatrics/neonatology, Ullevaal UH and the National Center for Epilepsy, Oslo
  • 1986-88 Post doc (NFR) The Nobel Institute for Neurophysiology, Karolinska Institute, Stockholm, Sweden
  • 1985-86 Post doc (NFR) Ullevaal UH, Oslo
  • 1984-85 Turnus kandidat Elverum
  • 1982-83 Locum Senior Lecturer in Physiology, Inst of Physiology, UiO
  • 1975-82 Medical School UiO with 1978 as full time student researcher (physiology)
  • 1972-75 Physiotherapy work and Examen Philosophicum  UiO 1974
  • 1970-72  Oslo Physiotherapy School
  • State School education in Horten 1958-70


  • 2011: The Vice Chancellors Impact award for 2011 University of Bristol
  • 2010: Elected member of Academia Europaea
  • 2007: Elected member of the Norwegian Academy of Science and Letters
  • 2007: The Tooley lecturerer, University of San Fransisco
  • 2005: The Peter Tizard lecturerer, The Neonatal Society, United Kindom

Positions held

  • Member on steering commeettee for Randomised Controlled Trial of hypothermia during echmo treatment in neonates (The NEST trial, UK)
  • Member of data monitoring commette for RCT of cooling after perinatal asphyxia (The ICE trial, Australia) 
  • 2008-2014: Specialist advisor for National Institute for Health and Clinical Excellence (NICE) UK
  • 2009- Editorial Board Therapeutic Hypothermia and Temperature Management


  • Professor of Anaesthesiology John Dingley, University  Department of Anaestehsiology, University of Swansea, UK
  • Dr Xun Liu, PhD, The Neonatal Neuroscience lab, University of Bristol, UK
  • Professor Henrik Hagberg, Physiology and Obstetrics, University of Gothenburg, Sweden
  • Professor of Physiology and Pediatrcis Alistar Gunn, University of Auckland,NZ
  • Professor of Neonatal Medicine, Drude Fugelseth, Oslo University Hospitals, section Ullevaal, Oslo 
  • Professor of  Anestesiology, Petter Andreas Steen, Universitetet of Oslo, Oslo University hospitals ,section Ullevaal, Oslo
Tags: Newborn, Organ physiology, Oxygen deprivation, Lack of oxygen, Therapeutic hypothermia and xenon inhalation, Body temperature, Peripheral circulation and cardiac function


  • Dingley, John; Okano, Satomi; Lee-Kelland, Richard; Scull-Brown, Emma; Thoresen, Marianne & Chakkarapani, Ela (2020). Closed circuit xenon delivery for 72h in neonatal piglets following hypoxic insult using an ambient pressure automated control system: Development, technical evaluation and pulmonary effects. PLOS ONE.  ISSN 1932-6203. . doi: 10.1371/journal.pone.0224447 Full text in Research Archive.
  • Wood, Thomas Ragnar; Gundersen, Julia Kristine; Falck, Mari; Maes, Elke; Osredkar, Damjan; Løberg, Else Marit; Sabir, Hemmen; Walløe, Lars & Thoresen, Marianne (2020). Variability and sex-dependence of hypothermic neuroprotection in a rat model of neonatal hypoxic–ischaemic brain injury: a single laboratory meta-analysis. Scientific Reports.  ISSN 2045-2322.  10:10833, s 1- 13 . doi: 10.1038/s41598-020-67532-2 Full text in Research Archive.
  • Chakkarapani, Ela & Thoresen, Marianne (2019). Brain and whole body cooling, In  MacDonald's Atlas of Procedures in Neonatology.  Lamy, Wolters Kluwer.  ISBN 9781496394255.  Chapter 45.
  • Frikstad, Kari-Anne; Molinari, Elisa; Thoresen, Marianne; Ramsbottom, Simon A; Hughes, Frances; Letteboer, Stef J.F.; Gilani, Sania; Schink, Kay Oliver; Stokke, Trond; Geimer, Stefan; Pedersen, Lotte B; Giles, Rachel H; Akhmanova, Anna; Roepman, Ronald; Sayer, John A & Patzke, Sebastian (2019). A CEP104-CSPP1 Complex Is Required for Formation of Primary Cilia Competent in Hedgehog Signaling. Cell reports.  ISSN 2211-1247.  28(7), s 1907- 1922.e6 . doi: 10.1016/j.celrep.2019.07.025
  • Gunn, Alistair J & Thoresen, Marianne (2019). Neonatal encephalopathy and hypoxic-ischemic encephalopathy.. Handbook of Clinical Neurology.  ISSN 0072-9752.  162, s 217- 237 . doi: 10.1016/B978-0-444-64029-1.00010-2
  • Jary, Sally; Lee-Kelland, Richard; Tonks, James; Cowan, Frances Mary; Thoresen, Marianne & Chakkarapani, Elavazhagan (2019). Motor performance and cognitive correlates in children cooled for neonatal encephalopathy without cerebral palsy at school age. Acta Paediatrica.  ISSN 0803-5253. . doi: 10.1111/apa.14780
  • Lee-Kelland, Richard; Jary, Sally; Tonks, James; Cowan, Frances Mary; Thoresen, Marianne & Chakkarapani, Ela (2019). School-age outcomes of children without cerebral palsy cooled for neonatal hypoxic-ischaemic encephalopathy in 2008-2010. Archives of Disease in Childhood: Fetal and Neonatal Edition.  ISSN 1359-2998. . doi: 10.1136/archdischild-2018-316509
  • Tonks, James; Cloke, Grace; Lee-Kelland, Richard; Jary, Sally; Thoresen, Marianne; Cowan, Frances & Chakkarapani, Ela (2019). Attention and visuo-spatial function in children without cerebral palsy who were cooled for neonatal encephalopathy: a case-control study. Journal of Building Performance Simulation.  ISSN 1940-1493.  33(7), s 894- 898 . doi: 10.1080/02699052.2019.1597163 Show summary
  • Walløe, Lars; Hjort, Nils Lid & Thoresen, Marianne (2019). Start cooling as soon as possible. Acta Paediatrica.  ISSN 0803-5253.  108(4), s 771- 771 . doi: 10.1111/apa.14710
  • Walløe, Lars; Hjort, Nils Lid & Thoresen, Marianne (2019). Why results from Bayesian Statistical analyses of clinical trials with a strong prior and small sample sixes may be misleading. Acta Paediatrica.  ISSN 0803-5253.  (108), s 1190- 1191 . doi: 10.111/apa.14800 Full text in Research Archive.
  • Wassink, Guido; Davidson, Joanne O.; Dhillon, Simerdeep K.; Zhou, Kelly; Bennet, Laura; Thoresen, Marianne & Gunn, Alistair J. (2019). Therapeutic hypothermia in neonatal hypoxic-ischemic encephalopathy. Current Neurology and Neuroscience Reports.  ISSN 1528-4042.  19:2(2), s 1- 10 . doi: 10.1007/s11910-019-0916-0
  • El-Dib, Mohamed; Terrie, E; Inder, Terrie E; Chalak, Lina F; Massaro, An N; Thoresen, Marianne & Gunn, Alistair J (2018). Should therapeutic hypothermia be offered to babies With mild neonatal encephalopathy in the first 6 hours after birth?. Pediatric Research.  ISSN 0031-3998. . doi: 10.1038/s41390-019-0291-1 Full text in Research Archive. Show summary
  • Falck, Mari; Osredkar, Damjan; Maes, Elke; Flatebø, Torun; Wood, Thomas Ragnar; Walløe, Lars; Sabir, Hemmen & Thoresen, Marianne (2018). Hypothermia is neuroprotective after severe hypoxic-ischaemic brain injury in neonatal rats pre-exposed to PAM3CSK4. Developmental Neuroscience.  ISSN 0378-5866.  40(3), s 189- 197 . doi: 10.1159/000487798 Show summary
  • Falck, Mari; Osredkar, Damjan; Wood, Thomas Ragnar; Maes, Elke; Flatebø, Torun; Sabir, Hemmen & Thoresen, Marianne (2018). Neonatal Systemic Inflammation Induces Inflammatory Reactions and Brain Apoptosis in a Pathogen-Specific Manner.. Neonatology.  ISSN 1661-7800.  113(3), s 212- 220 . doi: 10.1159/000481980
  • Sabir, Hemmen; Dingley, John; Scull-Brown, Emma; Chakkarapani, Ela & Thoresen, Marianne (2018). Fentanyl induces cerebellar internal granular cell layer apoptosis in healthy newborn pigs. Frontiers in Neurology.  ISSN 1664-2295.  9(MAY) . doi: 10.3389/fneur.2018.00294 Full text in Research Archive.
  • Walløe, Lars; Hjort, Nils Lid & Thoresen, Marianne (2018). Major concerns about late hypothermia study. Acta Paediatrica.  ISSN 0803-5253. . doi: 10.1111/apa.14640 Full text in Research Archive.
  • Falck, Mari; Osredkar, Damjan; Maes, Elke; Flatebø, Torun; Wood, Thomas Ragnar; Sabir, Hemmen & Thoresen, Marianne (2017). Hypothermic neuronal rescue from infection-sensitised hypoxic-ischaemic brain injury is pathogen dependent. Developmental Neuroscience.  ISSN 0378-5866.  39(1-4), s 238- 247 . doi: 10.1159/000455838
  • Liu, Xun; Jary, Sally; Cowan, Frances & Thoresen, Marianne (2017). Reduced infancy and childhood epilepsy following hypothermia-treated neonatal encephalopathy. Epilepsia.  ISSN 0013-9580.  58(11), s 1902- 1911 . doi: 10.1111/epi.13914
  • Skranes, Janne Helen; Løhaugen, Gro; Schumacher, Eva Margrethe; Osredkar, Damjan; Server, Andrés; Cowan, Frances Mary; Stiris, Tom; Fugelseth, Drude & Thoresen, Marianne (2017). Amplitude-Integrated Electroencephalography Improves the Identification of Infants with Encephalopathy for Therapeutic Hypothermia and Predicts Neurodevelopmental Outcomes at 2 Years of Age. Journal of Pediatrics.  ISSN 0022-3476.  187, s 34- 42 . doi: 10.1016/j.jpeds.2017.04.041
  • Tann, Cally J.; Martinello, KA; Sadoo, S; Lawn, JN; Seale, AC; Vega-Poblete, M; Russell, NJ; Baker, CJ; Bartlett, L; Cutland, C; Gravett, MG; Ip, M; Le Doare, K; Mahdi, SA; Rubens, CE; Saha, SK; Schraq, S; Sobanjo-Ter Meulen, A; Vekemans, J; Heath, PT; GBS Neotatal Encephalopathy, Investigator Group & Thoresen, Marianne (2017). Neonatal encephalopathy With goup B streptpococcal disease worldwide: Systematic review, investigator Group datasets and Meta-analysis. Clinical Infectious Diseases.  ISSN 1058-4838.  s 173- 189 . doi: 10.1093/cid/cix662
  • Thoresen, Marianne; Gunn, A J; Robertson, Nicola J; Laptook, Abbot R; Barks, J D; Wassink, Guido & Bennet, Laura (2017). Therapeutic hypothermia translates from ancient history in to practice. Pediatric Research.  ISSN 0031-3998.  81(1-2), s 202- 209 . doi: 10.1038/pr.2016.198
  • Wood, Thomas Ragnar; Hobbs, C; Brun, AC; Falck, Mari; Løberg, Else Marit & Thoresen, Marianne (2017). Rectal temperature in the first five hours after hypoxia-ischaemia critically affetcs neuropathological outcomes in neonatale rats. Pediatric Research.  ISSN 0031-3998. . doi: 10.1038/pr.2017.51
  • Elstad, Maja; Liu, Xun & Thoresen, Marianne (2016). Heart rate response to therapeutic hypothermia in infants with hypoxic–ischaemic encephalopathy. Resuscitation.  ISSN 0300-9572.  106, s 53- 57 . doi: 10.1016/j.resuscitation.2016.06.023
  • Hemmen, Sabir; Wood, Thomas Ragnar; Gill, Hannah; Liu, Xun; Dingley, John & Thoresen, Marianne (2016). Xenon depresses aEEG background voltage activity whilst maintaining cardiovascular stability in sedated healthy newborn pigs. Journal of the Neurological Sciences.  ISSN 0022-510X.  363, s 140- 144 . doi: 10.1016/j.jns.2016.02.051 Full text in Research Archive.
  • Kochanek, P; Kitagawa, RS; Batchelor, P & Thoresen, Marianne (2016). Central Nervous System Injury and Temperature Management. Therapeutic Hypothermia and Temperature Management.  ISSN 2153-7658.  6(3), s 112- 115 . doi: 10.1089/ther.2016.29014.pjk
  • Sabir, Hemmen; Osredkar, Damjan; Maes, Elke; Wood, Thomas Ragnar & Thoresen, Marianne (2016). Xenon combined with therapeutic hypothermia is not neuroprotective after severe hypoxia-ischemia in neonatal rats. PLOS ONE.  ISSN 1932-6203.  11(6) . doi: 10.1371/journal.pone.0156759
  • Wood, Thomas Ragnar; Osredkar, Damjan; Puchades, Maja Amedjkouh; Maes, Elke; Falck, Mari; Flatebø, Torun; Walløe, Lars; Sabir, Hemmen & Thoresen, Marianne (2016). Treatment temperature and insult severity influence the neuroprotective effects of therapeutic hypothermia. Scientific Reports.  ISSN 2045-2322.  6 . doi: 10.1038/srep23430 Full text in Research Archive.
  • Wood, Thomas Ragnar; Smit, Elisa; Maes, Elke; Osredkar, Damjan; Falck, Mari; Elstad, Maja & Thoresen, Marianne (2016). Monitoring of cerebral blood flow during hypoxia-ischemia and resuscitation in the neonatal rat using laser speckle imaging. Physiological Reports.  ISSN 2051-817X.  4(7), s 1- 14 . doi: 10.14814/phy2.12749 Full text in Research Archive.
  • Aquilina, Kristian & Thoresen, Marianne (2015). A newborn piglet survival model of post-hemorrhagic ventricular dilatation, In Jerome Y. Yager (ed.),  Animal Models of Neurodevelopmental Disorders.  Humana Press.  ISBN 978-1-4939-2708-1.  [Foreløpig ukjent].
  • Chakkarapani, Elavazhagan & Thoresen, Marianne (2015). The Newborn Pig Global Hypoxic-Ischemic Model of Perinatal Brain and Organ Injury, In Jerome Y. Yager (ed.),  Animal Models of Neurodevelopmental Disorders.  Humana Press.  ISBN 978-1-4939-2708-1.  [Foreløpig ukjent].
  • Dingley, John; Liu, Xun; Gill, Hannah; Smit, Elisa; Sabir, Hemmen; Tooley, James; Chakkarapani, Ela; Windsor, David & Thoresen, Marianne (2015). The feasibility of using a portable xenon delivery device to permit earlier xenon ventilation with therapeutic cooling of neonates during ambulance retrieval. Anesthesia and Analgesia.  ISSN 0003-2999.  120(6), s 1331- 1336 . doi: 10.1213/ANE.0000000000000693
  • Gunn, Alistair J & Thoresen, Marianne (2015). Animal studies of neonatal hypothermic neuroprotection have translated well in to practice. Resuscitation.  ISSN 0300-9572.  97, s 88- 90 . doi: 10.1016/j.resuscitation.2015.03.026
  • Hoque, Nicholas; Liu, Xun; Chakkarapani, Elavazhagan & Thoresen, Marianne (2015). Minimal systemic hypothermia combined with selective head cooling evaluated in a pig model of hypoxia-ischemia. Pediatric Research.  ISSN 0031-3998.  77(5), s 674- 680 . doi: 10.1038/pr.2015.31
  • Jary, Sally; Smit, Elisa; Liu, Xun; Cowan, Frances & Thoresen, Marianne (2015). Less severe cerebral palsy outcomes in infants treated with therapeutic hypothermia. Acta Paediatrica.  ISSN 0803-5253.  104(12), s 1241- 1247 . doi: 10.1111/apa.13146
  • Liu, Xun; Dingley, John; Scull-Brown, Emma & Thoresen, Marianne (2015). Adding 5 hours delayed xenon to delayed hypothermia treatment improves long term function in neonatal rats surviving to adulthood. Pediatric Research.  ISSN 0031-3998.  77, s 779- 783 . doi: 10.1038/pr.2015.49
  • Osredkar, Damjan; Sabir, Hemmen; Falck, Mari; Wood, Thomas Ragnar; Maes, Elke; Flatebø, Torun; Puchades, Maja Amedjkouh & Thoresen, Marianne (2015). Hypothermia Does Not Reverse Cellular Responses Caused by Lipopolysaccharide in Neonatal Hypoxic-Ischaemic Brain Injury. Developmental Neuroscience.  ISSN 0378-5866.  37(4-5), s 390- 397 . doi: 10.1159/000430860
  • Skranes, Janne Helen; Cowan, Frances; Stiris, Tom; Fugelseth, Drude; Thoresen, Marianne & SERVER, ANDRES (2015). Brain imaging in cooled encephalopathic neonates does not differ between four and 11 days after birth. Acta Paediatrica.  ISSN 0803-5253.  104(8), s 752- 758 . doi: 10.1111/apa.13016
  • Smit, Elisa; Liu, Xun; Gill, Hannah; Jary, Sally; Wood, Thomas Ragnar & Thoresen, Marianne (2015). The effect of resuscitation in 100% oxygen on brain injury in a newborn rat model of severe hypoxic-ischaemic encephalopathy. Resuscitation.  ISSN 0300-9572.  96, s 214- 219 . doi: 10.1016/j.resuscitation.2015.07.050
  • Smit, Elisa; Liu, Xun; Jary, Sally; Cowan, Frances & Thoresen, Marianne (2015). Cooling neonates who do not fulfil the standard cooling criteria - short and long term outcomes. Acta Paediatrica.  ISSN 0803-5253.  104(2), s 138- 145 . doi: 10.1111/apa.12784
  • Thoresen, Marianne (2015). Who should we cool after perinatal asphyxia?. Seminars in Fetal & Neonatal Medicine.  ISSN 1744-165X.  20(2), s 66- 71 . doi: 10.1016/j.siny.2015.01.002
  • Thoresen, Marianne & Sabir, Hemmen (2015). Epilepsy: Neonatal seizures still lack safe and effective treatment. Nature Reviews Neurology.  ISSN 1759-4758.  11(6), s 311- 312 . doi: 10.1038/nrneurol.2015.74
  • Whitelaw, Andrew; Osredkar, Damjan & Thoresen, Marianne (2015). Neurological & Neuromuscular Disorders, In Mhairi G. MacDonald & Mary M. K. Seshia (ed.),  Avery's Neonatology: Pathophysiology and Management of the Newborn (Seventh Edition).  Lippincott Williams & Wilkins.  ISBN 9781451192681.  46.  s 994 - 1016
  • Wood, Thomas Ragnar & Thoresen, Marianne (2015). Physiological responses to hypothermia. Seminars in Fetal & Neonatal Medicine.  ISSN 1744-165X.  20(2), s 87- 96 . doi: 10.1016/j.siny.2014.10.005
  • Osredkar, Damjan; Thoresen, Marianne; Maes, Elke; Flatebø, Torun; Elstad, Maja & Sabir, Hemmen (2014). Hypothermia is not neuroprotective after infection-sensitized neonatal hypoxic-ischemic brain injury. Resuscitation.  ISSN 0300-9572.  85(4), s 567- 572 . doi: 10.1016/j.resuscitation.2013.12.006
  • Azzopardi, D.; Strohm, B; Marlow, N; Brocklehurst, P; Halliday, H; Juszczak, E; Kapellou, O; Levene, Malcolm; Thoresen, Marianne; Tusor, N; Whitelaw, A & Edwards, D (2014). Effects of hypothermia for perinatal asphyxia on childhood outcomes – The TOBY Children Study. New England Journal of Medicine.  ISSN 0028-4793. . doi: 10.1056/NEJMoa1315788
  • Chakkarapani, Ela; Davis, Jonathan & Thoresen, Marianne (2014). Therapeutic hypothermia delays the C-reactive protein response and suppresses white blood cell and platelet count in infants with neonatal encephalopathy. Archives of Disease in Childhood: Fetal and Neonatal Edition.  ISSN 1359-2998.  99(6), s F458- F463 . doi: 10.1136/archdischild-2013-305763
  • Curtis, DJ; Thoresen, Marianne & Case, CP (2014). Secretions from placenta, after hypoxia/reoxygenation, can damage developing neurones of brain under experimental conditions. Experimental Neurology.  ISSN 0014-4886. . doi: 10.1016/j.expneurol.2014.05.003
  • Dingley, John; Tooley, James; Liu, Xun; Scull-Brown, Emma; Elstad, Maja; Chakkarapani, Elavazhagan; Sabir, Hemmen & Thoresen, Marianne (2014). Xenon Ventilation During Therapeutic Hypothermia in Neonatal Encephalopathy: A Feasibility Study. Pediatrics.  ISSN 0031-4005.  133(5), s 809- 818 . doi: 10.1542/peds.2013-0787
  • Elstad, Maja; Walløe, Lars; Holme, Nathalie; Maes, Elke & Thoresen, Marianne (2014). Respiratory sinus arrhythmia stabilizes mean arterial blood pressure at high-frequency interval in healthy humans. European Journal of Applied Physiology.  ISSN 1439-6319.  115(3), s 521- 530 . doi: 10.1007/s00421-014-3042-3
  • Gill, Hannah; Thoresen, Marianne; Bishop, Sarah; Smit, Elisa; Liu, Xun; Walløe, Lars & Dingley, John (2014). Equipotent subanesthetic concentrations of sevoflurane and xenon preventing cold-stimulated vocalization of neonatal rats. Anesthesiology.  ISSN 0003-3022.  121(6), s 1194- 1202 . doi: 10.1097/aln.0000000000000423

View all works in Cristin

  • Thoresen, Marianne (2021). Corpus callosum morphology, microstructure and outcomes in children without cerebral palsy cooled for neonatal hypoxic-ischemic encephalopathy. Abstract ID: 3538308.
  • Thoresen, Marianne & Gundersen, Julie K (2021). Morphine and fentanyl exposure during therapeutic hypothermia do not affect neurodevelopmental outcome at 18-24 months of age. Abstract ID: 3539552.
  • Thoresen, Marianne & Jary, Sally (2021). Motor correlates of brain structural connectivity in school-age children treated with therapeutic hypothermia for neonatal encephalopathy. Abstract ID: 3539104.
  • Thoresen, Marianne & Chakkarapani, Ela (2020). Association between neonatal neuroimaging, 18month cognitive and school-age full-scale IQ scores in children without cerebral palsy, cooled for neonatal encephalopathy.
  • Thoresen, Marianne; Wood, TR; Gundersen, J; Falck, Mari; Maes, Elke; Osredkar, Damjan; Løberg, Else Marit; Sabir, Hemmen & Walløe, Lars (2020). Variability and sex-dependence of hypothermic neuroprotection in a rat model of neonatal hypoxic-ischaemic brain injury: a single laboratory meta-analysis.
  • Hollung, Sandra Julsen & Thoresen, Marianne (2018, 13. juni). Forekomsten og alvorlighetsgraden av cerebral parese har gått ned. [TV].  NRK Dagsrevyen.
  • Thoresen, Marianne (2018). Combining two good treatments makes it worse. (Commentary on Interaction between hypothermia and delayed mesenchymal stem cell therapy in neonatal hypoxic-ischemic brain injury). Brain, behavior, and immunity.  ISSN 0889-1591. . doi: 10.1016/j.bbi.2018.04.008
  • Thoresen, Marianne (2018). European Standards of Care for Newborn Health:Postnatal management of newborn infants with hypoxic ischaemic encephalopathy (HIE). Issued by: European Foundation for the Care of Newborn Infants (EFCNI). November 2018.
  • Thoresen, Marianne (2018). Hva oppnår vi ved nedkjøling av nyfødte med oksygenmangel.
  • Thoresen, Marianne (2018). The past and future of Neonatal Neuroprotection.
  • Thoresen, Marianne (2018, 11. juli). <li value="209"> Thoresen M. On BBC 11th July 2018: [TV].  BBC.
  • Thoresen, Marianne; van Bel, Frank; Murray, D; Saliba, E; Buonocore, G; Hellstrøm-Westas, L & Zimmermann, L (2018). Postnatal management of newborn infants with hypoxic ischaemic encephalopathy (HIE). Show summary
  • Thoresen, Marianne (2017). Are small brains different from adults - why is therapeutic hypothermia so effective in newborns?.
  • Thoresen, Marianne (2017). Entry criteria for Therapeutic are drifting - does it matter?.
  • Thoresen, Marianne (2017). Epilepsy and the need for drug treatment in infancy and early school years after perinatal asphyxia and therapeutic hypothermia.
  • Thoresen, Marianne (2017). Gases for the brain.
  • Thoresen, Marianne (2017). Reduced sub-cortical grey matter volume is Associated With functional outcome at 6-8 years in children without cerebral palsy, who were cooled for neonatal encephalopathy.
  • Thoresen, Marianne (2017). Selection Criteria for 3 days of Therapeutic Hypothermia (TH) treatment after newborn asphyxia is based on aEEG depression. At 2 years, only 2% of TH infants have seizures needing regular AED treatment in a large SWE cohort'.
  • Thoresen, Marianne (2017). Tackling perinatal asphyxia. Does keeping the newborn brain cold after lack of oxygen always reduce brain injury?.
  • Thoresen, Marianne (2017). Targeted Temperature management in the very young.
  • Thoresen, Marianne & Falck, Mari (2017). Hypothermia plus human Umbilical-Cord Blood Cells is neuroprotective in a severe neonatal hypoxicischaemic brain injury model.
  • Thoresen, Marianne; Falck, Mari & Maes, Elke (2017). Pathogen specific changes in core temperature and neuroinflammation in the neonatal rat.
  • Chakkarapani, Ela & Thoresen, Marianne (2016). C-Reactive Protein Response in Infants Cooled for Neonatal Encephalopathy Is Delayed in Females More Than Males.
  • Falck, Mari; Maes, Elke; Flatebo, Torun; Wood, Thomas Ragnar; Sabir, Hemmen; Osredkar, Damjan & Thoresen, Marianne (2016). Gram-positive Septicemia Sensitises The Neonatal Brain To Hypoxic-ischemic Injury, Without Inhibiting The Neuroprotective Effect Of Hypothermia.
  • Lee-Kelland, Richard; Dingley, John; Okano, S; Scull-Brown, Emma; Thoresen, Marianne & Chakkarapani, Ela (2016). Xenon as Neuroprotection: A Demonstration of an Automated Delivery System.
  • Smit, Elisa; Wood, Thomas Ragnar; Elstad, Maja; Liu, Xun & Thoresen, Marianne (2016). The effect of resuscitation in 100% Oxygen on cerebral blood flow and neuropathology in a newborn rat model of hypoxia-ischaemia.
  • Steinsland, Tonje & Thoresen, Marianne (2016, 20. november). Vårt lille land : 'Cooling babies'. [TV].
  • Thoresen, Marianne (2016). Cooling the right children with the optimal protocol using valid short and long term outcome examinations - are we getting any better?.
  • Thoresen, Marianne (2016). Hypothermia and beyond. (Perinatal Asphyxia).
  • Thoresen, Marianne (2016, 21. november). 'Lille Tobias var i ferd med å dø - da gjorde lege Marianne noe ingen hadde gjort før'. [TV].
  • Thoresen, Marianne (2016). Xenon and hypothermia in neonates.
  • Thoresen, Marianne; Basu, S K; Kaiser, J R; Guffey, D; Minard, C G; Guillet, Ronnie & Gunn, A J (2016). Hypoglycaemia and hyperglycaemia are associated with unfavourable outcome in infants with hypoxic ischaemic encephalopathy: a post hoc analysis of the CoolCap Study. Archives of Disease in Childhood: Fetal and Neonatal Edition.  ISSN 1359-2998.  s 149- 155 . doi: 10.1136/archdischild-2015-308733
  • Thoresen, Marianne & Herefordshire & Worcester, BBC Radio (2016, 19. august). Interview following-up on progress of a baby who had been enrolled in a clinical trial. [Radio].
  • Wood, Thomas Ragnar; Skranes, Janne Helen; Falck, Mari; Lohaugen, GC; Stiris, Tom; Loberg, EM; Fugelseth, Drude & Thoresen, Marianne (2016). Core Temperature After Neonatal Hypoxia-Ischaemia Predicts Long-term Cerebral Injury.
  • Chakkarapani, Ela; Aquilina, Julian; Lee-Kelland, Richard; Jary, Sally; Liu, Xun & Thoresen, Marianne (2015). Morphine exposure and neurodevelopment outcome in cooled neonatal encephalopathy infants with mild cerebral dysfunction.
  • Falck, Mari; Osredkar, Damjan; Maes, Elke; Wood, Thomas Ragnar; Puchades, Maja Amedjkouh; Sabir, Hemmen & Thoresen, Marianne (2015). Systemic Inflammation Negates Hypothermic Neuroprotection in a Neonatal HIE-model.
  • Falck, Mari; Osredkar, Damjan & Thoresen, Marianne (2015). Hypothermia does not reverse cellular responses caused by lipopolysaccharide in neonatal hypoxic ischemic brain injury.
  • Lee-Kelland, Richard; Chakkarapani, Ela; Jary, Sally; Liu, Xun & Thoresen, Marianne (2015). Temperature Instability Post Rewarming in Neonates Who Have Received Therapeutic Hypothermia.
  • Sabir, Hemmen; Maes, Elke; Liu, Xun; Dingley, John & Thoresen, Marianne (2015). Fentanyl induces cerebellar internal granular cell layer apoptosis in healthy newborn pigs.
  • Sabir, Hemmen; Osredkar, Damjan; Maes, Elke; Wood, Thomas Ragnar & Thoresen, Marianne (2015). Therapeutic Hypothermia Combined With Inhaled Xenon in Newborn Rats: the Ongoing Challenge following severe hypoxicischemic brain injury.
  • Thoresen, Marianne (2015). Editorial: Cooling after perinatal asphyxia. Seminars in Fetal & Neonatal Medicine.  ISSN 1744-165X.  20(2) . doi: 10.1016/j.siny.2015.01.003
  • Thoresen, Marianne (2015). Hypothermia after perinatal asphyxia; do we select and cool the right babies with the optimal cooling protocol and follow up agreements?.
  • Thoresen, Marianne (2015). Optimal hypothermia treatment: an update from experimental and clinical research.
  • Thoresen, Marianne (2015). Optimal resuscitation followed by optimal hypothermia with and without added xenon inhalation.
  • Thoresen, Marianne (2015). Who should we cool, for how long and at what temperature?.
  • Thoresen, Marianne; Chakkarapani, Ela; Walløe, Lars; Løberg, Else Marit; Maes, Elke; Liu, Xun & Osredkar, Damjan (2015). No cardiac protection from hypothermia or xenon inhalation after hypoxia-ischemia in newborn pigs.
  • Wood, Thomas Ragnar; Osredkar, Damjan; Flatebø, Torun; Falck, Mari; Maes, Elke & Thoresen, Marianne (2015). Temperature Dependence Of Hypothermic Neuroprotection In A R Model Of Neonatal Hypoxic Ischaemic Encephalopathy.
  • Wood, Thomas Ragnar; Osredkar, Damjan; Flatebø, Torun; Falck, Mari; Maes, Elke & Thoresen, Marianne (2015). Temperature Dependence Of Hypothermic Neuroprotection in a Rat Model of Neonatal Hypoxic Ischaemic Enchephopathy.
  • Davis, Jonathan; Liu, Xun; Gill, Hannah; Smit, Elisa; Chakkarapani, Ela & Thoresen, Marianne (2014). Inclusion Benefit for Neonates in the Control Arm of a Randomized Controlled Trial of Xenon With Cooling.

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Published Apr. 13, 2011 2:41 PM - Last modified May 20, 2021 11:13 AM