Anners Lerdal

• Lindberg, Maren Falch; Aamodt, Arild; Badawy, Mona; Bergvad, Ingvild Buset; Borchgrevink, Petter Chr. & Furnes, Ove Nord [Show all 21 contributors for this article] (2021). The effectiveness of exercise therapy and education plus cognitive behavioral therapy, alone or in combination with total knee arthroplasty in patients with knee osteoarthritis – study protocol for the MultiKnee trial. BMC Musculoskeletal Disorders. ISSN 1471-2474. 22:1054, p. 1–14. doi: 10.1186/s12891-021-04924-z. Show summary

  Background One in five patients report chronic pain following total knee arthroplasty (TKA) and are considered non-improvers. Psychological interventions such as cognitive behavioral therapy (CBT), combined with exercise therapy and education may contribute to reduced pain an improved function both for patients with OA or after TKA surgery, but the evidence for the effectiveness of such interventions is scarce. This randomized controlled trial with three arms will compare the clinical effectiveness of patient education and exercise therapy combined with internet-delivered CBT (iCBT), evaluated either as a non-surgical treatment choice or in combination with TKA, in comparison to usual treatment with TKA in patients with knee OA who are considered candidates for TKA surgery. Methods The study, conducted in three orthopaedic centers in Norway will include 282 patients between ages 18 and 80, eligible for TKA. Patients will be randomized to receive the exercise therapy + iCBT, either alone or in combination with TKA, or to a control group who will undergo conventional TKA and usual care physiotherapy following surgery. The exercise therapy will include 24 one hour sessions over 12 weeks led by a physiotherapist. The iCBT program will be delivered in ten modules. The physiotherapists will receive theoretical and practical training to advise and mentor the patients during the iCBT program. The primary outcome will be change from baseline to 12 months on the pain sub-scale from the Knee Injury and Osteoarthritis Outcome Score (KOOS). Secondary outcomes include the remaining 4 sub-scales from the KOOS (symptoms, function in daily living, function in sports and recreation, and knee-related quality of life), EQ-5D-5L, the Pain Catastrophizing Scale, the 30-s sit-to-stand test, 40-m walking test and ActiGraph activity measures. A cost-utility analysis will be performed using QALYs derived from the EQ-5D-5L and registry data. Discussion This is the first randomized controlled trial to investigate the effectiveness of exercise therapy and iCBT with or without TKA, to optimize outcomes for TKA patients. Findings from this trial will contribute to evidence-based ersonalized treatment recommendations for a large proportion of OA patients who currently lack an effective treatment option. Trial registration Clinicaltrials.gov: NCT03771430. Registered: Dec 11, 2018.

• Kabashi, Saranda; Gamboa, Danil; Vindenes, Vigdis; Berg, Thomas; Hilberg, Thor Arthur & Jørgenrud, Benedicte Marie [Show all 8 contributors for this article] (2021). Multimorbidity, psychoactive substance use and psychological distress among acute medically ill patients: A cross-sectional study. BMJ Open. ISSN 2044-6055. 11(11). doi: 10.1136/bmjopen-2021-052428.
• Jørgenrud, Benedicte Marie; Kabashi, Saranda; Nadezhdin, Aleksei; Bryun, Evgeny; Koshkina, Evgenya & Tetenova, Elena [Show all 15 contributors for this article] (2021). The Association between the Alcohol Biomarker Phosphatidylethanol (PEth) and Self-Reported Alcohol Consumption among Russian and Norwegian Medical Patients. Alcohol and Alcoholism. ISSN 0735-0414. 56(6), p. 726–736. doi: 10.1093/alcalc/agab013.
• Rognsvåg, Turid; Lindberg, Maren Falch; Lerdal, Anners; Stubberud, Jan Egil; Furnes, Ove Nord & Holm, Inger [Show all 11 contributors for this article] (2021). Development of an internet-delivered cognitive behavioral therapy program for use in combination with exercise therapy and education by patients at increased risk of chronic pain following total knee arthroplasty. BMC Health Services Research. ISSN 1472-6963. 21(1), p. 1–14. doi: 10.1186/s12913-021-07177-7. Full text in Research Archive
• Kjeverud, Anita; Andersson, Stein; Lerdal, Anners; Schanke, Anne-Kristine & Østlie, Kristin (2021). A cross-sectional study exploring overlap in post-stroke fatigue caseness using three fatigue instruments: Fatigue Severity Scale, Fatigue Questionnaire and the Lynch’s Clinical Interview. Journal of Psychosomatic Research. ISSN 0022-3999. 150. doi: 10.1016/j.jpsychores.2021.110605.
• Johansen Skogestad, Ingrid; Kirkevold, Marit; Larsson, Petra; Borge, Christine Råheim; Indredavik, Bent & Gay, Caryl [Show all 7 contributors for this article] (2021). Post-stroke fatigue: an exploratory study with patients and health professionals to develop a patient-reported outcome measure. Journal of Patient-Reported Outcomes. ISSN 2509-8020. 5. doi: 10.1186/s41687-021-00307-z. Full text in Research Archive
• Monsen, Ragnhild Elisabeth; Herlofson, Bente Brokstad; Gay, Caryl; Fjeld, Katrine Gahre; Hove, Lene Hystad & Malterud, Karl Egil [Show all 11 contributors for this article] (2021). A mouth rinse based on a tea solution of Salvia officinalis for oral discomfort in palliative cancer care: A randomized controlled trial. Supportive Care in Cancer. ISSN 0941-4355. doi: 10.1007/s00520-021-06021-2. Full text in Research Archive Show summary

  Background: Few clinical studies evaluate interventions to reduce oral discomfort among patients in palliative care. Aim: This study examines the efficacy of a Salvia officinalis (SO) based herbal mouth rinse compared to conventional normal saline (NS) in order to improve oral health. Design: A block-randomized controlled trial. Data were collected before and after a 4-day intervention with either SO (n=44) or NS (n=44). Numerical rating scales (NRS, 0-10) and 12 items from the European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire-Oral Health 17 (EORTC QLQ-OH17) measured patient-reported oral symptoms. An oral examination was performed before and after the intervention. Setting/participants: This study included adult patients with late-stage cancer in an inpatient hospice unit. Results: Of the 88 patients included (mean age=63.9 years, SD=10.6), 73 (83%) completed the study. At baseline, 78% reported dry mouth on the EORTC QLQ-OH17, and 80% rated dry mouth ≥4 on the NRS. Total oral health scores based on the 12 EORTC QLQ-OH17 items improved similarly in both groups (p

• Aouizerat, Bradley E.; Byun, Eeeseung; Pullinger, Clive R.; Gay, Caryl; Lerdal, Anners & Lee, Kathryn A. (2020). Sleep Disruption and Duration are Associated with Variants in Genes Involved in Energy Homeostasis in Adults with HIV/AIDS. Sleep Medicine. ISSN 1389-9457. 82, p. 84–95. doi: 10.1016/j.sleep.2020.08.028. Full text in Research Archive
• Lindberg, Maren Falch; Miaskowski, Christine; Rustøen, Tone; Cooper, Bruce A.; Aamodt, Arild & Lerdal, Anners (2020). Preoperative risk factors associated with chronic pain profiles following total knee arthroplasty. European Journal of Pain. ISSN 1090-3801. p. 1–13. doi: 10.1002/ejp.1703. Full text in Research Archive
• Enbakom, Mestawet Getachew; Lerdal, Anners; Småstuen, Milada Cvancarova; Gay, Caryl; Aamodt, Arild & Tesfaye, Million [Show all 7 contributors for this article] (2020). High levels of preoperative pain and fatigue are red flags for moderate‐severe pain 12 months after total knee arthroplasty—A longitudinal cohort study. Musculoskeletal Care. ISSN 1478-2189. p. 1–7. doi: 10.1002/msc.1522. Full text in Research Archive Show summary

  Background: Moderate/severe pain after total knee arthroplasty (TKA) is a poor surgical outcome. Many studies have identified preoperative risk factors of painafter TKA, but studies of the joint contributions of co-occurring symptoms arelacking. Methods: Patients undergoing primary TKA (n=202) were enrolled in a longitu-dinal cohort study. Preoperatively, patients completed questionnaires measuring demographics and symptoms (pain, fatigue, sleep problems and depression). Painwas re-assessed 12 months after TKA. Logistic regression analysis was used to compute the probabilities of moderate-severe pain at 12 months based on preoperative symptom levels, and results were combined into a risk matrix. Results: More than one-third (40%) of patients (n=187) reported moderate-severepain after TKA. Among preoperative risk factors included in the logistic regressionanalyses were age, sex, pain, fatigue, sleep problems and depression. Adjusting forpossible confounders, fatigue (p=0.02) and pain (p=0.01) were significant riskfactors for moderate-severe pain at 12-months follow-up and were retained in the final risk matrix. The co-occurrence of high-preoperative fatigue and pain scores resulted in 57% estimated probability of moderate-severe pain at 12 months.Similarly, the co-occurrence of low-preoperative fatigue and pain scores resulted in14% estimated probability of moderate-severe pain 12 months after TKA. Conclusion: The combination of high fatigue and pain scores prior to surgery was akey risk factor for moderate-severe pain 12 months after TKA. Mapping of these factors could be used preoperatively to identify patients who are at risk to expe-rience a poor outcome of TKA.

• Gamboa, Danil; Jørgenrud, Benedicte Marie; Bryun, Evgeny A.; Vindenes, Vigdis; Koshkina, Evgenya A. & Nadezhdin, Aleksei V. [Show all 17 contributors for this article] (2020). Prevalence of psychoactive substance use among acutely hospitalised patients in Oslo and Moscow: a cross-sectional, observational study. BMJ Open. ISSN 2044-6055. 10:e032572(9), p. 1–15. doi: 10.1136/bmjopen-2019-032572. Full text in Research Archive
• Olsen, Unni Solveig Johansen; Lindberg, Maren Falch; Denison, Eva Marie-Louise; Rose, Christopher James; Gay, Caryl & Aamodt, Arild [Show all 11 contributors for this article] (2020). Predictors of chronic pain and level of physical function in total knee arthroplasty: a protocol for a systematic review and meta-analysis. BMJ Open. ISSN 2044-6055. 10, p. 1–9. doi: 10.1136/bmjopen-2020-037674. Full text in Research Archive Show summary

  Abstract Introduction One in five patients undergoing total knee arthroplasty (TKA) experience unchanged or worse pain and physical function 1 year after surgery. Identifying risk factors for unfavourable outcomes is necessary to develop tailored interventions to minimise risk. There is a need to review more current literature with updated methodology that addresses the limitations of earlier systematic reviews and meta-analyses. We present a Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols compliant protocol for a systematic review and meta-analysis of predictors of chronic pain and impaired function after TKA. Methods and analysis This review will include prospective longitudinal observational studies, or randomised trials (including cluster and crossover designs) that report arm-wise predictors of chronic postsurgical pain or impaired physical function at 3 months, 6 months or 12 months. A comprehensive literature search of studies published between 2000 and 2019 will be performed in Medline, Embase, CINAHL, Cochrane Library and PEDro. Blinded assessment with consensus agreement will be applied for inclusion of studies, data extraction and assessment of bias risk (Quality in Prognosis Studies tool). The co-primary outcomes, pain and impaired function, at 12 months after TKA will be analysed separately. Estimates of association between each outcome and any preoperative or intraoperative factor that may predict chronic pain or impaired physical function will be extracted from the included studies, where possible. For randomised studies, results will only be extracted from TKA arms (or the first period of crossover trials). Estimates of association from the primary evidence will be synthesised narratively, and quantitatively using multivariate meta-analysis to provide ‘pooled’ estimates of association. Subgroup and sensitivity analyses will be performed. Certainty of evidence for each predictor will be derived from the Grading of Recommendations Assessment, Development and Evaluation framework. Ethics and dissemination No ethical issues are associated with this project. The results from this review will be published in peer-reviewed journals and presented at international conferences.

• Rehman, Yasser; Lindberg, Maren Falch; Arnljot, Kristine; Gay, Caryl; Lerdal, Anners & Aamodt, Arild (2020). More severe radiographic osteoarthritis is associated with increased improvements in patients' health state following a total knee arthroplasty. Journal of Arthroplasty. ISSN 0883-5403. 35(11). doi: 10.1016/j.arth.2020.06.025. Full text in Research Archive Show summary

  Background To assess whether preoperative radiological severity of osteoarthritis (OA) is related to the level of improvement in patients’ health state measured 1 year after total knee arthroplasty (TKA). Methods Radiographic severity of OA was graded using the Kellgren-Lawrence (KL) classification. Two independent observers were blinded to patients’ outcome scores. Health-related quality of life was measured using EQ-5D-3L preoperatively and at 12-month follow-up. The 5 dimensions of the EQ-5D were converted into a health state index score. The association between KL grade and improvement in health state score was analyzed using multiple linear regression. Results Among 156 consecutive patients (68% females, mean age 69 years) who underwent primary TKA, 3 knees (2%) were classified as KL grade 2, 115 as KL grade 3 (74%), and 38 as KL grade 4 (24%). Follow-up rate was 77%. There was substantial intra-rater and inter-rater agreement (Cohen’s kappa = 0.80 and 0.79). Most patients (64%) had clinically significant improvement in their health state score 1 year after TKA. However, after adjusting for relevant covariates, patients with severe OA (KL grade 4) were found to have significantly more improvement in their health state score than patients with mild or moderate OA (KL grade 2 or 3, respectively). Separate analysis of the 5 EQ-5D dimensions showed that the KL group differences were most evident in the “usual activities” and “pain/discomfort” dimensions. Conclusion Patients with severe OA have significantly more improvement in their usual activities and pain/discomfort 1 year after TKA than patients with less severe OA.

• Bonsaksen, Tore; Skogstad, Laila; Grimholt, Tine Kristin; Heir, Trond; Ekeberg, Øivind & Lerdal, Anners [Show all 7 contributors for this article] (2020). Substance use in the Norwegian general population: Prevalence and associations with disease . Journal of Substance Use. ISSN 1465-9891. doi: 10.1080/14659891.2020.1784303. Full text in Research Archive
• Bragstad, Line Kildal; Lerdal, Anners Vetle; Gay, Caryl L.; Kirkevold, Marit; Lee, Kathryn A. & Lindberg, Maren Falch [Show all 10 contributors for this article] (2020). Psychometric properties of a short version of Lee Fatigue Scale used as a generic PROM in persons with stroke or osteoarthritis: assessment using a Rasch analysis approach. Health and Quality of Life Outcomes. ISSN 1477-7525. 18, p. 1–8. doi: 10.1186/s12955-020-01419-8. Full text in Research Archive
• Lindberg, Maren Falch; Schweitz, Turid Undebakke; Aamodt, Arild; Gay, Caryl & Lerdal, Anners (2020). High pre- and postoperative symptom burden in non-responders to total knee arthroplasty. PLOS ONE. ISSN 1932-6203. 15(5)(5), p. 1–14. doi: 10.1371/journal.pone.0233347.
• Kjeverud, Anita; Østlie, Kristin; Schanke, Anne-Kristine; Gay, Caryl; Thoresen, Magne & Lerdal, Anners (2020). Trajectories of fatigue among stroke patients from the acute phase to 18 months post-injury: A latent class analysis. PLOS ONE. ISSN 1932-6203. 15(4), p. 1–14. doi: 10.1371/journal.pone.0231709. Full text in Research Archive Show summary

  Using GMM, three latent classes of fatigue trajectories over 18 months were identified, characterized by differing levels of fatigue: low, moderate and high. The mean FSS score for each class remained relatively stable across all four time points. In the univariate analyses, age

• Bredal, Inger Schou; Bonsaksen, Tore; Ekeberg, Øivind; Skogstad, Laila; Grimholt, Tine Kristin & Lerdal, Anners [Show all 7 contributors for this article] (2020). Sexual assault and the association with health, quality of life and self-efficacy in the general Norwegian population. Journal of Interpersonal Violence. ISSN 0886-2605. doi: 10.1177/0886260520926307. Full text in Research Archive
• Bonsaksen, Tore; Heir, Trond; Skogstad, Laila; Grimholt, Tine K.; Ekeberg, Øivind & Lerdal, Anners [Show all 7 contributors for this article] (2020). Daily use of alcohol in the Norwegian general population: Prevalence and associated factors. Drugs and alcohol today. ISSN 1745-9265. doi: 10.1108/DAT-02-2020-0010. Full text in Research Archive
• Tollisen, Anita; Flatø, Berit; Selvaag, Anne Marit G; Aasland, Astrid; Ingebrigtsen, Trude & Sagen, Joakim [Show all 7 contributors for this article] (2019). Treatment Satisfaction with and Adherence to Disease-Modifying Antirheumatic Drugs in Adult Patients with Juvenile Idiopathic Arthritis. Arthritis care & research. ISSN 2151-464X. doi: 10.1002/acr.24113.
• Kabashi, Saranda; Vindenes, Vigdis; Bryun, Eugeniy Alekseevich; Koshkina, Evgenia A.; Nadezhdin, Alexey V. & Tetenova, Elena J. [Show all 16 contributors for this article] (2019). Harmful alcohol use among acutely ill hospitalized medical patients in Oslo and Moscow: A cross-sectional study. Drug and Alcohol Dependence. ISSN 0376-8716. 204:107588, p. 1–9. doi: 10.1016/j.drugalcdep.2019.107588. Full text in Research Archive
• Bonsaksen, Tore; Ekeberg, Øivind; Skogstad, Laila; Heir, Trond; Grimholt, Tine Kristin & Lerdal, Anners [Show all 7 contributors for this article] (2019). Self-rated global health in the Norwegian general population. Health and Quality of Life Outcomes. ISSN 1477-7525. 17(1). doi: 10.1186/s12955-019-1258-y. Full text in Research Archive
• Hugøy, Therese; Lerdal, Anners; Rustøen, Tone & Oksholm, Trine (2019). Predicting postoperative fatigue in surgically treated lung cancer patients in Norway: a longitudinal 5-month followup study. BMJ Open. ISSN 2044-6055. 9(9), p. 1–9. doi: 10.1136/bmjopen-2018-028192. Full text in Research Archive
• Heir, Trond; Bonsaksen, Tore; Grimholt, Tine Kristin; Ekeberg, Øivind; Skogstad, Laila & Lerdal, Anners [Show all 7 contributors for this article] (2019). Serious life events and post-traumatic stress disorder in the Norwegian population. BJPsych Open. ISSN 2056-4724. 5(e82), p. 1–7. doi: 10.1192/bjo.2019.62. Full text in Research Archive
• Tollisen, Anita; Selvaag, Anne Marit G; Aasland, Astrid; Lerdal, Anners & Flatø, Berit (2019). Longitudinal Health Status from Early Disease to Adulthood and Associated Prognostic Factors in Juvenile Idiopathic Arthritis. Journal of Rheumatology. ISSN 0315-162X. 46(10), p. 1335–1344. doi: 10.3899/jrheum.180948.
• Lerdal, Anners; Hofoss, Dag; Gay, Caryl & Fagermoen, May Solveig (2019). Perception of illness among patients with heart failure is related to their general health independently of their mood and functional capacity. Journal of Patient-Reported Outcomes. ISSN 2509-8020. 3:55, p. 1–7. doi: 10.1186/s41687-019-0142-1. Full text in Research Archive
• Skogestad, Ingrid Johansen; Kirkevold, Marit; Indredavik, Bent; Gay, Caryl & Lerdal, Anners Vetle (2019). Lack of content overlap and essential dimensions – A review of measures used for post-stroke fatigue. Journal of Psychosomatic Research. ISSN 0022-3999. 124. doi: 10.1016/j.jpsychores.2019.109759. Full text in Research Archive
• Aarnes, Rannveig; Stubberud, Jan & Lerdal, Anners (2019). A literature review of factors associated with fatigue after stroke and a proposal for a framework for clinical utility. Neuropsychological Rehabilitation. ISSN 0960-2011. p. 1–28. doi: 10.1080/09602011.2019.1589530.
• Grimholt, Tine Kristin; Bonsaksen, Tore; Bredal, Inger Schou; Heir, Trond; Lerdal, Anners & Skogstad, Laila [Show all 7 contributors for this article] (2019). Flight anxiety reported from 1986 to 2015. Aerospace Medicine and Human Performance. ISSN 2375-6314. 90(4), p. 384–388. doi: 10.3357/AMHP.5125.2019.
• Bjelland, Bente; Fagermoen, May Solveig; Lerdal, Anners & Bonsaksen, Tore (2019). Økt motivasjon for fysisk aktivitet blant personer med sykelig overvekt ett år etter deltakelse på lærings- og mestringskurs . Ergoterapeuten. ISSN 0800-3475. 62(2), p. 40–50. Full text in Research Archive
• Bonsaksen, Tore; Heir, Trond; Ekeberg, Øivind; Grimholt, Tine Kristin; Lerdal, Anners & Skogstad, Laila [Show all 7 contributors for this article] (2019). Self-evaluated anxiety in the Norwegian population: Prevalence and associated factors. Archives of Public Health. ISSN 0778-7367. 77(10). doi: 10.1186/s13690-019-0338-0. Full text in Research Archive
• Bredal, Inger Schou; Bonsaksen, Tore; Heir, Trond; Skogstad, Laila; Lerdal, Anners & Grimholt, Tine Kristin [Show all 7 contributors for this article] (2019). Optimists report fewer physical and mental health conditions than pessimists in the general Norwegian population. Health Psychology Report. ISSN 2353-4184. 7(1), p. 9–18. doi: 10.5114/hpr.2019.81003. Full text in Research Archive
• Stubberud, Jan; Edvardsen, Espen Madsen; Schanke, Anne-Kristine; Lerdal, Anners; Kjeverud, Anita & Schillinger, Andreas [Show all 7 contributors for this article] (2019). Description of a multifaceted intervention programme for fatigue after acquired brain injury: a pilot study. Neuropsychological Rehabilitation. ISSN 0960-2011. 29(6), p. 946–968. doi: 10.1080/09602011.2017.1344132. Show summary

  ABSTRACT The purpose of this pilot study was to describe and explore a group-based multifaceted intervention for patients with fatigue after acquired brain injury (ABI). We hypothesised that post-intervention changes would result in reduced fatigue, in addition to improved emotional health, sleep and attentional control. Eight subjects with traumatic brain injury (n = 3) and cerebrovascular insults (n = 5) were included. Inclusion was based upon the presence of fatigue complaints. The participants received 36 hours of intervention. Changes related to fatigue, emotional health and sleep was assessed with self-rating measures. Additionally, a neuropsychological test (Conners’ Continuous Performance Test II) was included as a measure of attentional control. All subjects were assessed at baseline, post-intervention, and at 3 and 9 months follow-up. Findings indicated reduced fatigue levels (post-intervention and 3 months follow-up), anxiety (9 months follow-up), and daytime sleepiness (3 and 9 months follow-up). Pilot results suggest that multifaceted group-based interventions may have the potential to alleviate symptoms of fatigue, anxiety and sleepiness after ABI. At an individual level, a low load of psychological distress, insomnia symptoms, dysexecutive symptoms, in addition to a strong sense of self-efficacy, may be central in order to reduce levels of fatigue. KEYWORDS: Fatigue, cognitive rehabilitation, brain injury, goal management, self-efficacy

• Rustøen, Tone; Lerdal, Anners; Gay, Caryl & Kottorp, Anders (2018). Rasch analysis of the Herth Hope Index in cancer patients. Health and Quality of Life Outcomes. ISSN 1477-7525. 16:196, p. 1–10. doi: 10.1186/s12955-018-1025-5. Full text in Research Archive
• Steindal, Simen Alexander; Torheim, Henny; Oksholm, Trine; Christensen, Vivi Lycke; Lee, Kathryn A & Lerdal, Anners [Show all 10 contributors for this article] (2018). The effectiveness of nursing interventions for breathlessness in people with chronic obstructive pulmonary disease: A systematic review and meta-analysis. Journal of Advanced Nursing. ISSN 0309-2402. doi: 10.1111/jan.13902. Full text in Research Archive
• Solheim, Jorunn; Gay, Caryl; Lerdal, Anners; Hickson, Louise & Kvaerner, Kari Jorunn (2018). An evaluation of motivational interviewing for increasing hearing aid use: A pilot study. Journal of american academy of audiology. ISSN 1050-0545. 29(8), p. 696–705. doi: 10.3766/jaaa.16184.
• Bonsaksen, Tore; Grimholt, Tine Kristin; Skogstad, Laila; Lerdal, Anners; Ekeberg, Øivind & Heir, Trond [Show all 7 contributors for this article] (2018). Self-diagnosed depression in the Norwegian general population - associations with neuroticism, extraversion, optimism, and general self-efficacy . BMC Public Health. ISSN 1471-2458. 18(1076). doi: 10.1186/s12889-018-5990-8. Full text in Research Archive
• Cumming, Toby B.; Yeo, Ai Beng; Jodie, Marquez; Churilov, Leonid; Annoni, Jean-Marie & Badaru, Umaru [Show all 19 contributors for this article] (2018). Investigating post-stroke fatigue: An individual participant data meta-analysis. Journal of Psychosomatic Research. ISSN 0022-3999. 113, p. 107–112. doi: 10.1016/j.jpsychores.2018.08.006.
• Larsson, Petra; Borge, Christine Råheim; Nygren-Bonnier, Malin; Lerdal, Anners & Edvardsen, Anne (2018). An evaluation of the short physical performance battery following pulmonary rehabilitation in patients with chronic obstructive pulmonary disease. BMC Research Notes. ISSN 1756-0500. 11(348). doi: 10.1186/s13104-018-3458-7.
• Lerdal, Anners; Sigurdsen, Line Wangsvik; Hammerstad, Heidi Irene; Granheim, Tove Irene & Gay, Caryl (2018). Associations between patient symptoms and falls in an acute care hospital: A cross-sectional study. Journal of Clinical Nursing (JCN). ISSN 0962-1067. 27(9-10), p. 1826–1835. doi: 10.1111/jocn.14364.
• Bonsaksen, Tore; Lerdal, Anners; Heir, Trond; Ekeberg, Øivind; Skogstad, Laila & Grimholt, Tine Kristin [Show all 7 contributors for this article] (2018). General self-efficacy in the Norwegian population: Differences and similarities between sociodemographic groups. Scandinavian Journal of Public Health. ISSN 1403-4948. doi: 10.1177/1403494818756701.
• Børsting, Tove; Tvedt, Christine Raaen; Johansen Skogestad, Ingrid; Granheim, Tove Irene; Gay, Caryl & Lerdal, Anners (2018). Prevalence of pressure ulcer and associated risk factors in middle- and older-aged medical inpatients in Norway. Journal of Clinical Nursing (JCN). ISSN 0962-1067. 27(3-4), p. e535–e543. doi: 10.1111/jocn.14088. Full text in Research Archive
• Tollisen, Anita; Selvaag, Anne Marit G; Aulie, Hanne Aaserud; Lilleby, Vibke; Aasland, Astrid & Lerdal, Anners [Show all 7 contributors for this article] (2017). Physical functioning, pain, and health-related quality of life in adults with juvenile idiopathic arthritis: a longitudinal 30-year followup study. Arthritis care & research. ISSN 2151-464X. 70(5), p. 741–749. doi: 10.1002/acr.23327.
• Kornilov, Nikolai; Lindberg, Maren Falch; Gay, Caryl; Saraev, Alexander; Kuliaba, Taras & Rosseland, Leiv Arne [Show all 7 contributors for this article] (2017). Higher physical activity and lower pain levels before surgery predict non-improvement of knee pain 1 year after TKA. Knee Surgery, Sports Traumatology, Arthroscopy. ISSN 0942-2056. 26(6), p. 1698–1708. doi: 10.1007/s00167-017-4713-5.
• Bredal, Inger Schou; Heir, Trond; Skogstad, Laila; Bonsaksen, Tore; Lerdal, Anners & Grimholt, Tine Kristin [Show all 7 contributors for this article] (2017). Population-based norms of the Life Orientation Test–Revised (LOT-R). International Journal of Clinical and Health Psychology. ISSN 1697-2600. 17(3), p. 216–224. doi: 10.1016/j.ijchp.2017.07.005. Full text in Research Archive
• Lerdal, Anners; Opheim, Randi; Gay, Caryl; Moum, Bjørn; Fagermoen, May Solveig & Kottorp, Anders (2017). Psychometric limitations of the 13-item Sense of Coherence Scale assessed by Rasch analysis. BMC Psychology. ISSN 2050-7283. 5(18). doi: 10.1186/s40359-017-0187-y.
• Lerdal, Anners; Gay, Caryl; Bonsaksen, Tore & Fagermoen, May Solveig (2017). Predictors of physical and mental health in persons with morbid obesity attending a patient education course - a two-year follow-up study. Health and Quality of Life Outcomes. ISSN 1477-7525. 15(1). doi: 10.1186/s12955-017-0675-z. Full text in Research Archive
• Alhaug, Johanne; Gay, Caryl; Henriksen, Christine & Lerdal, Anners (2017). Pressure ulcer is associated with malnutrition as assessed by Nutritional Risk Screening (NRS 2002) in a mixed hospital population. Food & Nutrition Research. ISSN 1654-6628. 61. doi: 10.1080/16546628.2017.1324230. Full text in Research Archive
• Saraev, Alexander; Lindberg, Maren Falch; Gay, Caryl; Rosseland, Leiv Arne; Lerdal, Anners & Kornilov, Nikolai [Show all 7 contributors for this article] (2017). What influence on early postoperative pain intensity after total knee arthorplasty? Travmatologiya i Ortopediya Rossii. ISSN 2311-2905. 23(1), p. 46–58. doi: 10.21823/2311-2905-2017-23-1-45-58. Full text in Research Archive Show summary

  Purpose: To describe the relationship of selected socio-demographic, clinical, and surgical factors with the severity and patterns of postoperative pain during the first three days following total knee arthroplasty. Material and methods. The sample included 100 patients (93 women and 7 men; mean age 63.5±7.8 years) with osteoarthritis admitted for primary total knee arthroplasty. Prior to surgery, standard measures were used to assess preoperative pain and other symptoms, clinical manifestations of osteoarthritis, functional status of the knee, comorbidities, functional abilities, quality of life, and other patient characteristics. Patterns of daily changes in postoperative pain characteristics were investigated with the use of individual diaries. Results. All the analyzed indicators of postoperative pain progressively decreased during the three days after surgery (p<.001), including the number of daily hours of moderate to severe pain (p<.001). Pain levels were generally higher among women than among men (p=.009). Of the analyzed preoperative factors, higher levels postoperative pain were correlated with higher levels of anxiety (p=.029) and preoperative pain intensity (p=.029). Among the perioperative factors, surgery duration longer than 90 minutes was associated with higher levels of postoperative pain in activity (p=.012) and more hours of moderate/severe pain (p=.008). Characteristics of postoperative pain were unrelated to level of patient education, social or family status, employment, lifestyle, or any other clinical or laboratory variables. Conclusion. Of the many factors previously associated with postoperative pain, only gender, anxiety and level of preoperative pain confirmed their importance in this study. Among the perioperative factors, surgery duration, which varied by the type of implant, was significantly associated with postoperative pain Levels.

• Lindberg, Maren Falch; Rustøen, Tone; Christine, Miaskowski; Rosseland, Leiv Arne & Lerdal, Anners (2017). The relationship between pain with walking and self-rated health 12 months following total knee arthroplasty: a longitudinal study. BMC Musculoskeletal Disorders. ISSN 1471-2474. 18(1). doi: 10.1186/s12891-017-1430-7. Full text in Research Archive
• Lerdal, Anners & Gay, Caryl (2017). Acute-Phase Fatigue Predicts Limitations with Activities of Daily Living 18 Months after First-Ever Stroke. Journal of Stroke & Cerebrovascular Diseases. ISSN 1052-3057. 26(3), p. 523–531. doi: 10.1016/j.jstrokecerebrovasdis.2016.11.130. Show summary

  Introduction: Fatigue during the acute phase following stroke has been shown to predict long-term physical health, specifically increased bodily pain and poorer self-rated general health. The aim of this analysis was to determine whether acute phase fatigue also predicts patients’ level of functioning with respect to activities of daily living (ADL) 18 months after first stroke. Methods: Patients with first-ever stroke (n=88) were recruited upon admission at two hospitals in Norway. Patients were assessed within 2 weeks following admission and at 18 months using the Barthel Index of Activities of Daily Living (BI), Fatigue Severity Scale, and Beck Depression Inventory II. The relationship between acute-phase fatigue and later ADL impairment (BI<20) was evaluated using multivariate logistic regression analysis controlling for relevant covariates and acute-phase ADL functioning. Results: Acute-phase fatigue was associated with ADL impairment at 18-month follow-up (p=.006), even when controlling for other predictors of ADL functioning, including age, gender, baseline work status, and acute-phase depressive symptoms and ADL function. Examining the reverse relationship, acute-phase ADL function was unrelated to fatigue 18 months after stroke. Conclusions: Our study indicates that acute-phase fatigue may be an independent risk factor for ADL impairment 18 months after stroke. The finding indicates that effective treatments for post-stroke fatigue both in the acute-phase and later in the recovery period may contribute to better stroke rehabilitation.

• Skogestad, Ingrid Johansen; Martinsen, Liv; Børsting, Tove; Granheim, Tove Irene; Ludvigsen, Eirin Sigurdssøn & Gay, Caryl [Show all 7 contributors for this article] (2017). Supplementing the Braden scale for pressure ulcer risk among Medical inpatients: the contribution of self-reported symptoms and standard Laboratory tests. Journal of Clinical Nursing (JCN). ISSN 0962-1067. 26(1-2), p. 202–214. doi: 10.1111/jocn.13438.
• Lindberg, Maren Falch; Miaskowski, Christine; Rustøen, Tone; Rosseland, Leiv Arne; Cooper, Bruce A. & Lerdal, Anners (2016). Factors that can predict pain with walking, 12 months after total knee arthroplasty: A trajectory analysis of 202 patients. Acta Orthopaedica. ISSN 1745-3674. 87(6), p. 600–606. doi: 10.1080/17453674.2016.1237440.

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• Lerdal, Anners (2021). Fatigue. In: Maggino F. (eds) Encyclopedia of Quality of Life and Well-Being Research . Springer Netherlands. ISBN 94-007-0753-3. 20 p.
• Rustøen, Tone & Lerdal, Anners (2021). Klinisk forskning innen helsefag. Fagbokforlaget. ISBN 9788245022926. 256 p.
• Lerdal, Anners (2020). Hvordan skrive den gode vitenskapelige artikkelen? Gyldendal Akademisk. ISBN 9788205538573. 80 p.

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• Steindal, Simen Alexander; Lindberg, Maren Falch; Aamodt, Arild; Småstuen, Milada Cvancarova; Lerdal, Anners & Dihle, Alfhild (2021). Persistent pain in patients reporting pain one year after total knee arthroplasty – a follow-up mixed methods study .
• Jørgenrud, Benedicte Marie; Bogstrand, Stig Tore; Vindenes, Vigdis; Johannessen, Aud; Wüsthoff, Linda Elise & Kunøe, Nikolaj [Show all 9 contributors for this article] (2021). Implementering av intervensjon for skadelig alkohol- og legemiddelbruk blant medisinske pasienter .
• Tollisen, Anita; Selvaag, Anne Marit; Aasland, Astrid; Lerdal, Anners & Flatø, Berit (2021). Fatigue, smerte, fysisk funksjon og helserelatert livskvalitet hos unge voksne med barneleddgikt.
• Ludvigsen, Eirin Sigurdssøn; Lindberg, Maren Falch; Aamodt, Arild; Lerdal, Anners; Bergvad, Ingvild Buset & Frøyen Lillegård, Julianne Helene (2021). Hva kan jeg forvente dersom jeg bli med i MultiKnee studien?
• Schweitz, Turid Undebakke; Lindberg, Maren Falch; Aamodt, Arild; Gay, Caryl & Lerdal, Anners (2021). Preoperative symptoms as risk factors for non-response to total knee arthroplasty.
• Rehman, Yasser; Lindberg, Maren Falch; Arnljot, Kristine; Gay, Caryl; Lerdal, Anners & Aamodt, Arild (2021). More Severe Radiographic Osteoarthritis Is Associated With Increased Improvement in Patients’ Health State Following a Total Knee Arthroplasty.
• Lindberg, Maren Falch; Miaskowski, Christine; Rustøen, Tone; Cooper, Bruce A; Aamodt, Arild & Lerdal, Anners (2021). Chronic pain profiles and associated risk factors following total knee arthroplasty - a prospective observational study.
• Ludvigsen, Eirin Sigurdssøn; Lindberg, Maren Falch; Bergvad, Ingvild Buset; Aamodt, Arild; Lerdal, Anners & Rognsvåg, Turid (2021). Bakgrunn for MultiKnee studien.
• Clarke, Sara & Lerdal, Anners (2021). Kildekritikk og litteratursøk. In Rustøen, Tone & Lerdal, Anners (Ed.), Klinisk forskning innen helsefag. Fagbokforlaget. ISSN 9788245022926. p. 178–197.
• Rustøen, Tone & Lerdal, Anners (2021). Finansiering av forskning. In Rustøen, Tone & Lerdal, Anners (Ed.), Klinisk forskning innen helsefag. Fagbokforlaget. ISSN 9788245022926. p. 239–247.
• Lerdal, Anners & Rustøen, Tone (2021). Hvordan skrive en god forskningssøknad. In Rustøen, Tone & Lerdal, Anners (Ed.), Klinisk forskning innen helsefag. Fagbokforlaget. ISSN 9788245022926. p. 225–238.
• Lerdal, Anners & Rustøen, Tone (2021). Hvordan bygge formell kompetanse og skrive en CV. In Rustøen, Tone & Lerdal, Anners (Ed.), Klinisk forskning innen helsefag. Fagbokforlaget. ISSN 9788245022926. p. 153–159.
• Rustøen, Tone & Lerdal, Anners (2021). Noen forskningsdesign ved evaluering av intervensjoner eller kliniske tiltak. In Rustøen, Tone & Lerdal, Anners (Ed.), Klinisk forskning innen helsefag. Fagbokforlaget. ISSN 9788245022926. p. 106–123.
• Rustøen, Tone & Lerdal, Anners (2021). Hvordan bygge opp gode forskningsgrupper og sterke miljøer for forskning. In Rustøen, Tone & Lerdal, Anners (Ed.), Klinisk forskning innen helsefag. Fagbokforlaget. ISSN 9788245022926. p. 71–84.
• Lerdal, Anners & Rustøen, Tone (2021). Formidling av forskning. In Rustøen, Tone & Lerdal, Anners (Ed.), Klinisk forskning innen helsefag. Fagbokforlaget. ISSN 9788245022926. p. 52–70.
• Marthe Kristin, Nereng & Lerdal, Anners (2021). Kunnskapsbasert praksis og tjenesteforbedring i kommunale helse- og omsorgstjenester. In Rustøen, Tone & Lerdal, Anners (Ed.), Klinisk forskning innen helsefag. Fagbokforlaget. ISSN 9788245022926. p. 198–224.
• Lerdal, Anners (2021). Etikk og personvern i forskning. In Rustøen, Tone & Lerdal, Anners (Ed.), Klinisk forskning innen helsefag. Fagbokforlaget. ISSN 9788245022926. p. 124–137.
• Lindberg, Maren Falch; Rustøen, Tone; Cooper, Bruce A; Aamodt, Arild & Lerdal, Anners Vetle (2021). Authors’ reply to the comment by Riddle et al. European Journal of Pain. ISSN 1090-3801. doi: 10.1002/ejp.1756.
• Lerdal, Anners (2020). Sleep and fatigue, It's not that simple.
• Gay, Caryl; Berg, Søren; Hansen, Aleksander Grande; Ihle-Hansen, Hege; Johansen Skogestad, Ingrid & Stubberud, Jan [Show all 8 contributors for this article] (2020). Fatigue and sleep apnea three months after first-ever stroke.
• Haukeland-Parker, Stacey Marie; Stafne, Signe Nilssen; Martijn A, Spruit; Lerdal, Anners & Johannessen, Hege Hølmo (2019). Urinary incontinence women with chronic obstructive pulmonary disease.
• Monsen, Ragnhild Elisabeth; Herlofson, Bente Brokstad; Gay, Caryl; Dahl, Marianne; Saghaug, Elisabeth & Slaaen, Joran [Show all 7 contributors for this article] (2019). Dry mouth - a missing symptom in multiple assessment tools?
• Monsen, Ragnhild Elisabeth; Herlofson, Bente Brokstad; Gay, Caryl; Fjeld, Katrine Gahre; Hove, Lene Hystad & Saghaug, Elisabeth [Show all 10 contributors for this article] (2019). A comparison of normal saline mouth rinse and mouth rinse based on Salvia officinalis in palliative care: A randomized controlled trial.
• Lindberg, Maren Falch; Rognsvåg, Turid; Badawy, Mona; Borchgrevink, Petter Chr.; Furnes, Ove & Gay, Caryl [Show all 13 contributors for this article] (2019). Optimal behandling av artrosepasienter - en feasibilitystudie (MultiKnee trial).
• Rognsvåg, Turid; Lindberg, Maren Falch; Borchgrevink, Petter Chr.; Furnes, Ove; Gay, Caryl & Holm, Inger [Show all 13 contributors for this article] (2018). Multi-Knee Trial. En feasibilty-studie av en intervensjon for artrosepasienter med økt risiko for langvarige smerter etter operasjon med kneprotese.
• Haukeland-Parker, Stacey Marie; Stafne, Signe Nilssen; Lerdal, Anners; Spruit, Martijn & Johannessen, Hege Hølmo (2018). Effekt av bekkenbunnstrening og teknikker for å dempe hoste på kvinner med KOLS og urininkontinens – preliminære resultater fra en RCT. .
• Monsen, Ragnhild Elisabeth; Herlofson, Bente Brokstad; Gay, Caryl; Saghaug, Elisabeth; Tollisen, Anita & Fjeld, Katrine Gahre [Show all 10 contributors for this article] (2018). Rekruttering av pasienter til en klinisk intervensjonsstudie i et Hospice.
• Kornilov, Nikolai; Lindberg, Maren Falch; Gay, Caryl; Saraev, Alexander; Kuliaba, Taras & Rosseland, Leiv Arne [Show all 7 contributors for this article] (2018). Høyere fysisk aktivitetsnivå og mindre preoperative smerter predikerer manglende forbedring etter innsetting av total kneprotese. Revmatologi BestPractice.
• Tollisen, Anita; Selvaag, Anne Marit; Ingebrigtsen, Trude Miljeteig; Aasland, Astrid; Lerdal, Anners & Flatø, Berit (2018). Treatment satisfaction in patients with juvenile idiopathic arthritis.
• Lindberg, Maren Falch; Rustøen, Tone; Rosseland, Leiv Arne & Lerdal, Anners (2018). Preoperative prediktorer for smerteforløp og livskvalitet etter kneproteseoperasjon.
• Schweitz, Turid Undebakke; Lindberg, Maren Falch; Ludvigsen, Eirin Sigurdssøn & Lerdal, Anners (2018). Preoperative symptomer hos kneprotesepasienter med tilbakevendende smerter ved gange.
• Lindberg, Maren Falch; Rustøen, Tone; Rosseland, Leiv Arne & Lerdal, Anners (2018). Smerter ved gange og selvrapportert helse etter innsatt kneprotese.
• Lindberg, Maren Falch; Aamodt, Arild & Lerdal, Anners (2018). A multidisciplinary intervention in total knee arthroplasty - a multicenter randomized controlled trial in patients on waiting list for TKA (The MULTI-KNEE trial).
• Bonsaksen, Tore; Fagermoen, May Solveig; Småstuen, Milada C & Lerdal, Anners (2018). Selvfølelse og positive og negative følelser etter pasientopplæring. BestPractice. Lungemedisin. 8(2), p. 18–21.
• Steindal, Simen Alexander; Oksholm, Trine; Torheim, Henny; Christensen, Vivi Lycke; Lee, Kathryn & Lerdal, Anners [Show all 10 contributors for this article] (2017). A systematic review of nursing interventions for breathlessness in COPD. European Clinical Respiratory Journal. ISSN 2001-8525. 50. doi: 10.1183/1393003.congress-2017.PA2582.
• Steindal, Simen Alexander; Oksholm, Trine; Torheim, Henny; Christensen, Vivi Lycke; Lee, Kathryn A & Lerdal, Anners [Show all 10 contributors for this article] (2017). A systematic review of nursing interventions for breathlessness in COPD.
• Gay, Caryl; Monsen, Ragnhild Elisabeth; Saghaug, Elisabeth; Herlofson, Bente Brokstad; Fjeld, Katrine Gahre & Hove, Lene Hystad [Show all 11 contributors for this article] (2017). Oral health symptoms that interfere with eating and drinking among hospice patient.
• Haukeland-Parker, Stacey Marie; Stafne, Signe Nilssen; Lerdal, Anners; Spruit, Martijn & Johannessen, Hege Hølmo (2016). Urinary incontinence amongst women with chronic obstructive pulmonary disease.
• Lindberg, Maren Falch; Rustøen, Tone; Rosseland, Leiv Arne & Lerdal, Anners (2016). Prediktorer for nedsatt gangfunksjon ett år etter innsatt kneprotese – en subgruppeanalyse.
• Lindberg, Maren Falch; Rustøen, Tone; Rosseland, Leiv Arne & Lerdal, Anners (2016). Smertepåvirkning av gangfunksjon gjennom det første året etter innsatt total kneprotese.
• Victor, Mattias Erik; Lau, Bjørn; Ruud, Torleif & Lerdal, Anners Vetle (2020). Patient characteristics and factors associated with post-treatment work participation in a Norwegian return to work programme for common mental disorders. Universitetet i Oslo.
• Rose, Christopher James; Olsen, Unni ; Lindberg, Maren Falch; Denison, Eva Marie-Louise; Aamodt, Arild & Lerdal, Anners (2020). A new multivariate meta-analysis model for many variates and few studies. arXiv.
• Olsen, Unni Solveig Johansen; Lerdal, Anners; Aamodt, Arild; Brox, Jens Ivar; Furnes, Ove & Denison, Eva Marie-Louise [Show all 8 contributors for this article] (2018). Preoperative and intraoperative predictors of persistent postoperative pain and impaired physical function in total knee arthroplasty - a systematic review of prognostic studies. PROSPERO, International prospective register of systematic reviews.
• Lindberg, Maren Falch; Lerdal, Anners; Rustøen, Tone & Rosseland, Leiv Arne (2017). Factors that predict the trajectories of aucte pain, pain with walking, and self-rated health after total knee arthroplasty - a longitudinal study. Reprosentralen, Universitetet i Oslo. ISSN 978-82-8377-122-0.

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