Hanne Scholz

Vice director, Senior researcher
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Phone +47 97514215
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Hanne Scholz is a senior researcher of Cell Transplantation and Regenerative Medicine and the Director of the Human Islet Isolation Facility at Oslo University Hospital.

In 2018 she joined the University of Oslo as principle investigator and vice director at The Hybrid Technology Hub Center of Excellence.

She is active in research in the fields of islet isolation and transplantation, beta cell replacement therapy, 3D bioprinting, tissue engineering, diabetes, stem cell biology, cellular therapy, and organ on a chip technology and has contributed to over 60 peer-reviewed publications. She works in a multidisciplinary research environment of basic scientists, medical clinicians, surgeons and bioengineering technicians.

Hanne Scholz holds a Bachelor Degree in Bioengineering from Bergen College of Engineering (1994) and a Master of Science in Human Physiology from the Faculty of Mathematics and Natural Sciences (2000) at UiO followed by a doctoral degree at the Faculty of Medicine, Institute of Clinical Medicine (2006).

 

Teaching:

  • Courses in Medicine and PhD programm, Faculty of Medicine, University of Oslo
  • Yearly between 5-10 lectures at different national/international meetings

 

Appointment:

  • Councillor 2017-2021 International Pancreas and Islet Transplantation Association (IPITA)
  • Councillor 2019-2023 European Society for Organ Transplantation (ESOT)
  • 2017-present Members of Scandia Transplant Nordic Pancreas and Islet Transplantation Group (NPiTG)
  • 2012-present Board member Nordic Network for Clinical Islet Transplantation (NNCIT)
  • 2018-present MC member of COST Action CA17116 (SPRINT)
  • 2015-present Primary Investigator, Oslo Diabetes Research Centre

 

Supervision:

Dr. Hanne Scholz has supervised the following PhD student at UiO to examination: Tormod Lund (2009), Afaf Sahraoui (2016), Kristine Kloster-Jensen (2018), Shadab Abadpour (2018), Simen W. Schive (2019), in addition to 2 Medical students, and 2 Master students.

She is supervising the following PhD students: Chencheng Wang (2020-), Kristine Fasting (2020-), Essi Niemi (2019-), and the following postdoctors: Shadab Abadpour, PhD (2019-2021), and Øystein Stakkestad, PhD (2019)

Tags: 3D bioprinting, diabetes, stem cell biology, organ on a chip, transplantation

Publications

  • Hrušková, Helena; Olsen, Christine; Řemínek, Roman; Wang, Chencheng; Aizenshtadt, Aleksandra & Krauss, Stefan Johannes Karl [Show all 10 contributors for this article] (2024). Preparative agarose gel electrophoresis for reducing matrix interferences of organoid cell medium prior to LC-MS analysis of insulin. Journal of Chromatography A. ISSN 0021-9673. 1717. doi: 10.1016/j.chroma.2024.464669.
  • Aizenshtadt, Aleksandra; Wang, Chencheng; Abadpour, Shadab; Menezes, Pedro Duarte; Wilhelmsen, Ingrid & Dalmao-Fernandez, Andrea [Show all 15 contributors for this article] (2024). Pump-Less, Recirculating Organ-on-Chip (rOoC) Platform to Model the Metabolic Crosstalk between Islets and Liver. Advanced Healthcare Materials. ISSN 2192-2640. doi: 10.1002/adhm.202303785.
  • Wang, Chencheng; Abadpour, Shadab; Olsen, Petter Angell; Wang, Daxin; Stokowiec, Justyna & Chera, Simona [Show all 11 contributors for this article] (2024). Glucose Concentration in Regulating Induced Pluripotent Stem Cells Differentiation Toward Insulin-Producing Cells. Transplant International. ISSN 0934-0874. 37. doi: 10.3389/ti.2024.11900.
  • Gramignoli, Roberto; Hofmann, Nicola; Agudo-Barriuso, Marta; Antica, Mariastefania; Flores, Ana I. & Girandon, Lenart [Show all 14 contributors for this article] (2024). Expert Revision of Key Elements for Clinical-Grade Production and Qualification of Perinatal Derivatives. Stem Cells Translational Medicine. ISSN 2157-6564. 13(1), p. 14–29. doi: 10.1093/stcltm/szad068.
  • Piemonti, Lorenzo; Scholz, Hanne; de Jongh, Dide; Kerr-Conte, Julie; van Apeldoorn, Aart & Shaw, James A. M. [Show all 14 contributors for this article] (2023). The Relevance of Advanced Therapy Medicinal Products in the Field of Transplantation and the Need for Academic Research Access: Overcoming Bottlenecks and Claiming a New Time. Transplant International. ISSN 0934-0874. 36. doi: 10.3389/ti.2023.11633.
  • Mathisen, Andreas Frøslev; Abadpour, Shadab; Legøy, Thomas Aga; Paulo, Joao A.; Ghila, Luiza Mihaela & Scholz, Hanne [Show all 7 contributors for this article] (2023). Global proteomics reveals insulin abundance as a marker of human islet homeostasis alterations. Acta Physiologica. ISSN 1748-1708. 239(2). doi: 10.1111/apha.14037. Full text in Research Archive
  • Olsen, Christine; Wang, Chencheng; Aizenshtadt, Aleksandra; Abadpour, Shadab; Lundanes, Elsa & Skottvoll, Frøydis Sved [Show all 11 contributors for this article] (2023). Simultaneous LC–MS determination of glucose regulatory peptides secreted by stem cell–derived islet organoids. Electrophoresis. ISSN 0173-0835. 44(21-22), p. 1682–1697. doi: 10.1002/elps.202300095. Full text in Research Archive
  • Abadpour, Shadab; Niemi, Essi Maria; Strid Orrhult, Linnea; Hermanns, Carolin; de Vries, Rick & Parreiras Nogueira, Liebert [Show all 12 contributors for this article] (2023). Adipose-Derived Stromal Cells Preserve Pancreatic Islet Function in a Transplantable 3D Bioprinted Scaffold. Advanced Healthcare Materials. ISSN 2192-2640. 12(32). doi: 10.1002/adhm.202300640. Full text in Research Archive
  • Oskarsdotter, Kristin; Säljö, Karin; Sämfors, Sanna; Niemi, Essi Maria; Li, Susann & Simonsson, Stina [Show all 10 contributors for this article] (2023). Autologous endothelialisation by the stromal vascular fraction on laminin-bioconjugated nanocellulose-alginate scaffolds. Biomedical Materials. ISSN 1748-6041. 18(4). doi: 10.1088/1748-605X/acdebb. Full text in Research Archive
  • LaLone, Vernon; Aizenshtadt, Aleksandra; Goertz, John; Skottvoll, Frøydis Sved; Mota, Marco Barbero & You, Junji [Show all 15 contributors for this article] (2023). Quantitative chemometric phenotyping of three-dimensional liver organoids by Raman spectral imaging. Cell Reports Methods. 3(4). doi: 10.1016/j.crmeth.2023.100440. Full text in Research Archive
  • Boix Lemonche, Gerard; Nagymihaly, Richard; Niemi, Essi Maria; Josifovska, Natasha; Johansen, Stian & Moe, Morten Carsten [Show all 8 contributors for this article] (2023). Intracorneal Implantation of 3D Bioprinted Scaffolds Containing Mesenchymal Stromal Cells Using Femtosecond-Laser-Assisted Intrastromal Keratoplasty. Macromolecular Bioscience. ISSN 1616-5187. 23. doi: 10.1002/mabi.202200422. Full text in Research Archive
  • Olsen, Christine; Wiborg, Elisa; Lundanes, Elsa; Abadpour, Shadab; Scholz, Hanne & Wilson, Steven Ray Haakon (2022). On-line reduction of insulin disulfide bonds with photoinduced radical reactions, upstream to nano liquid chromatography-mass spectrometry. Separation Science Plus (SSC plus). ISSN 2573-1815. 5(6), p. 220–227. doi: 10.1002/sscp.202200022.
  • Olsen, Christine; Wang, Chencheng; Abadpour, Shadab; Lundanes, Elsa; Hansen, Audun Skau & Skottvoll, Frøydis Sved [Show all 8 contributors for this article] (2022). Determination of insulin secretion from stem cell-derived islet organoids with liquid chromatography-tandem mass spectrometry. Journal of chromatography. B. ISSN 1570-0232. 1215. doi: 10.1016/j.jchromb.2022.123577. Full text in Research Archive
  • Kogler, Stian; Aizenshtadt, Aleksandra; Harrison, Sean; Skottvoll, Frøydis Sved; Berg, Henriette Engen & Abadpour, Shadab [Show all 14 contributors for this article] (2022). "Organ-in-a-Column" Coupled On-line with Liquid Chromatography-Mass Spectrometry. Analytical Chemistry. ISSN 0003-2700. 94(50), p. 17677–17684. doi: 10.1021/acs.analchem.2c04530. Full text in Research Archive
  • Berney, Thierry; Andres, Axel; Bellin, Melena D.; de Koning, Eelco J. P.; Johnson, Paul R. V. & Kay, Thomas W. H. [Show all 11 contributors for this article] (2022). A Worldwide Survey of Activities and Practices in Clinical Islet of Langerhans Transplantation. Transplant International. ISSN 0934-0874. 35. doi: 10.3389/ti.2022.10507.
  • Ward, Casey; Odorico, Jon S.; Rickels, Michael R.; Berney, Thierry; Burke, George W. & Kay, Thomas W.H. [Show all 14 contributors for this article] (2022). International Survey of Clinical Monitoring Practices in Pancreas and Islet Transplantation. Transplantation. ISSN 0041-1337. 106(8), p. 1647–1655. doi: 10.1097/TP.0000000000004058.
  • Sämfors, Sanna; Niemi, Essi Maria; Oskarsdotter, Kristin; Egea, Claudia Villar; Mark, Andreas & Scholz, Hanne [Show all 7 contributors for this article] (2022). Design and biofabrication of a leaf-inspired vascularized cell-delivery device. Bioprinting. ISSN 2405-8866. doi: 10.1016/j.bprint.2022.e00199. Full text in Research Archive
  • Kwak, Dongho; Combriat, Thomas Michel Daniel; Wang, Chencheng; Scholz, Hanne; Danielsen, Anne & Jensenius, Alexander Refsum (2022). Music for Cells? A Systematic Review of Studies Investigating the Effects of Audible Sound Played Through Speaker-Based Systems on Cell Cultures . Music & Science. ISSN 2059-2043. 5. doi: 10.1177/20592043221080965. Full text in Research Archive
  • Fernandez, Manuel Carrasco; Wang, Chencheng; Søviknes, Anne Mette; Bjørlykke, Yngvild; Abadpour, Shadab & Paulo, Joao A. [Show all 16 contributors for this article] (2022). Spatial Environment Affects HNF4A Mutation-Specific Proteome Signatures and Cellular Morphology in hiPSC-Derived β-Like Cells. Diabetes. ISSN 0012-1797. 71(4), p. 862–869. doi: 10.2337/db20-1279.
  • Piemonti, Lorenzo; Andres, Axel; Casey, John; de Koning, Eelco; Engelse, Marten & Hilbrands, Robert [Show all 19 contributors for this article] (2021). US food and drug administration (FDA) panel endorses islet cell treatment for type 1 diabetes: A pyrrhic victory? Transplant International. ISSN 0934-0874. p. 1182–1186. doi: 10.1111/tri.13930.
  • Berishvili, Ekaterine; Casiraghi, Federica; Cristiano, Amarelli; Scholz, Hanne; Piemonti, Lorenzo & Berney, Thierry [Show all 7 contributors for this article] (2021). Mini-organs forum: how to advance organoid technology to organ transplant community. Transplant International. ISSN 0934-0874. 34(9), p. 1588–1593. doi: 10.1111/tri.13988.
  • Abadpour, Shadab; Wang, Chencheng; Niemi, Essi Maria & Scholz, Hanne (2021). Tissue Engineering Strategies for Improving Beta Cell Transplantation Outcome. Current Transplantation Reports. 8(3), p. 205–219. doi: 10.1007/s40472-021-00333-2. Full text in Research Archive
  • Zhou, Alex-Xianghua; Mondal, Tanmoy; Tabish, Ali Mustafa; Abadpour, Shadab; Ericson, Elke & Smith, David M. [Show all 11 contributors for this article] (2021). The long noncoding RNA TUNAR modulates Wnt signaling and regulates human β-cell proliferation. American Journal of Physiology. Heart and Circulatory Physiology. ISSN 0363-6135. 320(4), p. E846–E857. doi: 10.1152/AJPENDO.00335.2020.
  • Ghila, Luiza; Legøy, Thomas Aga; Mathisen, Andreas Frøslev; Abadpour, Shadab; Paulo, Joao A. & Scholz, Hanne Bjørnson [Show all 8 contributors for this article] (2021). Chronically elevated exogenous glucose elicits antipodal effects on the proteome signature of differentiating human ipsc-derived pancreatic progenitors. International Journal of Molecular Sciences. ISSN 1661-6596. 22(7). doi: 10.3390/ijms22073698. Full text in Research Archive
  • Nordheim, Espen; Lindahl, Jørn Petter Hanto; Carlsen, Rasmus Kirkeskov; Åsberg, Anders; Birkeland, Kåre I. & Horneland, Rune [Show all 9 contributors for this article] (2021). Patient selection for islet or solid organ pancreas transplantation: experiences from a multidisciplinary outpatient-clinic approach. Endocrine Connections. ISSN 2049-3614. 10(2), p. 230–239. doi: 10.1530/EC-20-0519. Full text in Research Archive
  • Nano, Rita; Kerr-Conte, Julie; Scholz, Hanne; Engelse, Marten; Karlsson, Marie & Saudek, Frantisek [Show all 19 contributors for this article] (2020). Heterogeneity of Human Pancreatic Islet Isolation Around Europe: Results of a Survey Study. Transplantation. ISSN 0041-1337. 104(12), p. 190–196. doi: 10.1097/TP.0000000000002777.
  • Abadpour, Shadab; Tyrberg, Björn; Schive, Simen Walberg; Huldt, Charlotte; Gennemark, P & Ryberg, Erik [Show all 12 contributors for this article] (2020). Inhibition of the Prostaglandin D(2)-Gpr44/Dp2 Axis Improves Human Islet Survival and Function. Diabetologia. ISSN 0012-186X. 63(7), p. 1355–1367. doi: 10.1007/s00125-020-05138-z. Full text in Research Archive
  • Brandhorst, Heide; Brandhorst, Daniel; Abraham, Anju; Acreman, Samuel; Schive, Simen Walberg & Scholz, Hanne [Show all 7 contributors for this article] (2020). Proteomic profiling reveals the ambivalent character of the mesenchymal stem cell secretome: Assessing the effect of preconditioned media on isolated human islets. Cell Transplantation. ISSN 0963-6897. 29, p. 1–13. doi: 10.1177/0963689720952332. Full text in Research Archive
  • Abadpour, Shadab; Aizenshtadt, Aleksandra; Olsen, Petter Angell; Shoji, Kayoko; Wilson, Steven Ray Haakon & Krauss, Stefan [Show all 7 contributors for this article] (2020). Pancreas-on-a-Chip Technology for Transplantation Applications. Current Diabetes Reports. ISSN 1534-4827. 20. doi: 10.1007/s11892-020-01357-1. Full text in Research Archive
  • Kogler, Stian; Harrison, Sean; Aizenshtadt, Aleksandra; Skottvoll, Frøydis Sved; Abadpour, Shadab & Krauss, Stefan [Show all 10 contributors for this article] (2020). “Organoid-in-a-column” coupled on-line with liquid chromatography-mass spectrometry. bioRxiv. ISSN 2692-8205. doi: 10.1101/2020.09.08.282756.
  • Legøy, Thomas Aga; Vethe, Heidrun; Abadpour, Shadab; Strand, Berit Løkensgard; Scholz, Hanne & Paulo, Joao A. [Show all 9 contributors for this article] (2020). Encapsulation boosts islet-cell signature in differentiating human induced pluripotent stem cells via integrin signalling . Scientific Reports. ISSN 2045-2322. 10, p. 1–16. doi: 10.1038/s41598-019-57305-x. Full text in Research Archive
  • Legøy, Thomas Aga; Mathisen, Andreas Frøslev; Salim, Zaidon; Vethe, Heidrun; Bjørlykke, Yngvild & Abadpour, Shadab [Show all 11 contributors for this article] (2020). In vivo environment swiftly restricts human pancreatic progenitors toward mono-hormonal identity via a HNF1A/HNF4A mechanism. Frontiers in Cell and Developmental Biology. ISSN 2296-634X. 8:109, p. 1–14. doi: 10.3389/fcell.2020.00109. Full text in Research Archive
  • Berishvili, Ekaterine; Kaiser, Laurent; Cohen, Marie; Berney, Thierry; Scholz, Hanne Bjørnson & Fløisand, Yngvar [Show all 7 contributors for this article] (2020). Treatment of COVID-19 Pneumonia: the Case for Placenta-derived Cell Therapy. Stem Cell Reviews and Reports (SCRR). ISSN 2629-3269. p. 1–8. doi: 10.1007/s12015-020-10004-x. Full text in Research Archive
  • Amini, Maryam; Niemi, Essi Maria; Hisdal, Jonny; Kalvøy, Håvard; Tronstad, Christian & Scholz, Hanne [Show all 8 contributors for this article] (2020). Monitoring the quality of frozen-thawed venous segments using bioimpedance spectroscopy . Physiological Measurement. ISSN 0967-3334. 41(4). doi: 10.1088/1361-6579/ab85b7. Full text in Research Archive
  • Korsgren, Olle & Scholz, Hanne (2019). Cellular therapies in preclinical and clinical islet transplantation: Mesenchymal stem cells. In Orlando, Giuseppe (Eds.), Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas. Elsevier. ISSN 9780128148334. doi: https:/doi.org/10.1016/B978-0-12-814833-4.00064-2.
  • von Zur-Mühlen, Bengt; Scholz, Hanne; Hellman, Jarl; Korsgren, Olle & Lundgren, Torbjørn (2019). Treating diabetes with islet transplantation:Lessons learnt from the Nordic network for clinical islet transplantation. In Orlando, Giuseppe (Eds.), Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas. Elsevier. ISSN 9780128148334. doi: https:/doi.org/10.1016/B978-0-12-814833-4.00048-4.
  • Legøy, Thomas Aga; Ghila, Luiza; Vethe, Heidrun; Abadpour, Shadab; Mathisen, Andreas Frøslev & Paulo, Joao A. [Show all 9 contributors for this article] (2019). In vivo hyperglycemia exposure elicits distinct period-dependent effects on human pancreatic progenitor differentiation, conveyed by oxidative stress. Acta Physiologica. ISSN 1748-1708. 23:247577, p. 1–16. doi: 10.1111/apha.13433. Full text in Research Archive
  • Bergström, Marcus; Müller, Malin; Karlsson, Marie; Scholz, Hanne; Vethe, Nils Tore & Korsgren, Olle (2019). Comparing the Effects of the mTOR Inhibitors Azithromycin and Rapamycin on In Vitro Expanded Regulatory T Cells . Cell Transplantation. ISSN 0963-6897. 28(12), p. 1603–1613. doi: 10.1177/0963689719872488. Full text in Research Archive
  • Vethe, Heidrun; Legøy, Thomas Aga; Abadpour, Shadab; Strand, Berit Løkensgard; Scholz, Hanne & Paulo, Joao A. [Show all 9 contributors for this article] (2019). Encapsulation boosts islet-cell signature in differentiating human induced pluripotent stem cells via integrin signalling. bioRxiv. ISSN 2692-8205. doi: 10.1101/791442.
  • Vethe, Heidrun; Ghila, Luiza; Berle, Magnus; Hoareau, Laurence; Haaland, Øystein Ariansen & Scholz, Hanne [Show all 9 contributors for this article] (2019). The effect of WnT pathway modulators on human iPSC-derived pancreatic beta cell maturation. Frontiers in Endocrinology. ISSN 1664-2392. 10:293(MAY), p. 1–13. doi: 10.3389/fendo.2019.00293. Full text in Research Archive
  • Eich, Torsten M.; Ståhle, Magnus; Gustafsson, Bengt; Horneland, Rune; Lempinen, Marko & Lundgren, Torbjörn [Show all 12 contributors for this article] (2018). Calcium: A Crucial Potentiator for Efficient Enzyme Digestion of the Human Pancreas. Cell Transplantation. ISSN 0963-6897. 27(7), p. 1031–1038. doi: 10.1177/0963689718779350. Full text in Research Archive
  • Schive, Simen Walberg; Fjukstad, Ragnhild; Josefsen, Dag; Katavic, Marina; Abadpour, Shadab & Gullestad, Hans Petter [Show all 8 contributors for this article] (2018). Automated isolation and expansion of human adipose tissuederived stem cells for a seamless translation into clinical trials. CellR4 (repair, Replacement, Regenerative&Reprogramming. ISSN 2329-7042. 6(2).
  • Sokolova, Marina; Sahraoui, Afaf; Høyem, Merete; Øgaard, Jonas; Lien, Egil & Aukrust, Pål [Show all 9 contributors for this article] (2018). NLRP3 inflammasome mediates oxidative stress-induced pancreatic islet dysfunction. American Journal of Physiology. Endocrinology and Metabolism. ISSN 0193-1849. 315(5), p. E912–E923. doi: 10.1152/ajpendo.00461.2017.
  • Schuetz, Christian; Anazawa, Takayuki; Cross, Sarah E.; Labriola, Leticia; Meier, Raphael P.H. & Redfield, Robert R. [Show all 9 contributors for this article] (2018). β cell replacement therapy: The next 10 years. Transplantation. ISSN 0041-1337. 102(2), p. 215–229. doi: 10.1097/TP.0000000000001937.
  • Abadpour, Shadab; Halvorsen, Bente; Sahraoui, Afaf; Korsgren, Olle; Aukrust, Pål & Scholz, Hanne (2018). Interleukin-22 reverses human islet dysfunction and apoptosis triggered by hyperglycemia and LIGHT. Journal of Molecular Endocrinology. ISSN 0952-5041. 60(3), p. 171–183. doi: 10.1530/JME-17-0182.
  • Schive, Simen Walberg; Mirlashari, Mohammad Reza; Hasvold, Grete; Wang, Mengyu; Josefsen, Dag & Gullestad, Hans Petter [Show all 10 contributors for this article] (2017). Human Adipose-Derived Mesenchymal Stem Cells Respond to Short-Term Hypoxia by Secreting Factors Beneficial for Human Islets in Vitro and Potentiate Antidiabetic Effect in Vivo. Cell Medicine. ISSN 2155-1790. 9, p. 103–116. doi: 10.3727/215517917X693401.
  • Brandhorst, Daniel; Brandhorst, Heide; Acreman, Samuel; Schive, Simen Walberg; Scholz, Hanne & Johnson, Paul R.V. (2017). Hypoxia-induced damage in human islets is reduced with the use of mesenchymal stem cell–preconditioned medium. Transplantation Proceedings. ISSN 0041-1345. 49(10), p. 2330–2332. doi: 10.1016/j.transproceed.2017.11.003.
  • Hals, Ingrid Kathrin; Ohki, Tsuyoshi; Singh, Rinku; Ma, Zuheng; Björklund, Anneli & Balasuriya, Chandima Nirupa Dilruks [Show all 8 contributors for this article] (2017). Hyperoxia reduces insulin release and induces mitochondrial dysfunction with possible implications for hyperoxic treatment of neonates. Physiological Reports. ISSN 2051-817X. 5(19). doi: 10.14814/phy2.13447. Full text in Research Archive
  • Abadpour, Shadab; Göpel, Sven O; Schive, Simen Walberg; Korsgren, Olle; Foss, Aksel & Scholz, Hanne (2017). Glial cell-line derived neurotrophic factor protects human islets from nutrient deprivation and endoplasmic reticulum stress induced apoptosis. Scientific Reports. ISSN 2045-2322. 7(1). doi: 10.1038/s41598-017-01805-1.
  • Vethne, Heidrun; Bjørlykke, Yngvild; Ghila, Luiza; Paulo, Joao A.; Scholz, Hanne & Gygi, Steven P. [Show all 8 contributors for this article] (2017). Probing the missing mature β-cell proteomic landscape in differentiating patient iPSC-derived cells. Scientific Reports. ISSN 2045-2322. 7:4780, p. 1–14. doi: 10.1038/s41598-017-04979-w.
  • Schive, Simen Walberg; Foss, Aksel; Sahraoui, Afaf; Kloster-Jensen, Kristine; Hafsahl, Geir & Kvalheim, Gunnar [Show all 15 contributors for this article] (2017). Cost and clinical outcome of islet transplantation in Norway 2010-2015. Clinical Transplantation. ISSN 0902-0063. 31:e12871(1), p. 1–8. doi: 10.1111/ctr.12871.
  • Hals, Ingrid Kathrin; Singh, Rinku; Ma, Zuheng; Scholz, Hanne; Björklund, Anneli & Grill, Valdemar Erik Robert (2016). Culture at low glucose up-regulates mitochondrial function in pancreatic β cells with accompanying effects on viability. Islets. ISSN 1938-2014. 8(6), p. 165–176. doi: 10.1080/19382014.2016.1246637.
  • Kloster-Jensen, Kristine; Sahraoui, Afaf; Vethe, Nils Tore; Korsgren, Olle; Bergan, Stein & Foss, Aksel [Show all 7 contributors for this article] (2016). Treatment with tacrolimus and sirolimus reveals no additional adverse effects on human islets in vitro compared to each drug alone but they are reduced by adding glucocorticoids. Journal of Diabetes Research. ISSN 2314-6745. 2016. doi: 10.1155/2016/4196460. Full text in Research Archive
  • Halvorsen, Bente; Santilli, Francesca; Scholz, Hanne; Sahraoui, Afaf; Gulseth, Hanne Løvdal & Wium, Cecilie [Show all 20 contributors for this article] (2016). LIGHT/TNFSF14 is increased in patients with type 2 diabetes mellitus and promotes islet cell dysfunction and endothelial cell inflammation in vitro. Diabetologia. ISSN 0012-186X. 59, p. 2134–2144. doi: 10.1007/s00125-016-4036-y. Full text in Research Archive
  • Hals, Ingrid Katrin; Bruerberg, Simon Gustafsen; Ma, Zuheng; Scholz, Hanne; Björklund, Anneli & Grill, Valdemar Erik Robert (2015). Mitochondrial respiration in insulin-producing β-cells: General characteristics and adaptive effects of hypoxia. PLOS ONE. ISSN 1932-6203. doi: 10.1371/journal.pone.0138558. Full text in Research Archive
  • Kloster-Jensen, Kristine; Vethe, Nils Tore; Bremer, Sara; Abadpour, Shadab; Korsgren, Olle & Foss, Aksel [Show all 8 contributors for this article] (2015). Intracellular sirolimus concentration is reduced by tacrolimus in human pancreatic islets in vitro. Transplant International. ISSN 0934-0874. 28(10), p. 1152–1161. doi: 10.1111/tri.12617.
  • Schive, Simen Walberg; Scholz, Hanne; Sahraoui, Afaf; Kloster-Jensen, Kristine; Hafsahl, Geir & Korsgren, Olle [Show all 8 contributors for this article] (2015). Graft function 1 year after pregnancy in an islet-transplanted patient. Transplant International. ISSN 0934-0874. 28(10), p. 1235–1239. doi: 10.1111/tri.12596.
  • Sahraoui, Afaf; Winzell, Maria Sörhede; Gorman, Tracy; Smith, Dave M.; Skrtic, Stanko & Høyem, Merete [Show all 11 contributors for this article] (2015). The effects of exendin-4 treatment on graft failure: An animal study using a novel revascularized minimal human islet transplant model. PLOS ONE. ISSN 1932-6203. 10(3). doi: 10.1371/journal.pone.0121204. Full text in Research Archive
  • Halvorsen, Bente ; Holm, Sverre; Yndestad, Arne; Scholz, Hanne ; Sagen, Ellen Lund & Nebb, Hilde Irene [Show all 9 contributors for this article] (2014). Interleukin-10 increases reverse cholesterol transport in macrophages through its bidirectional interaction with liver X receptor α. Biochemical and Biophysical Research Communications - BBRC. ISSN 0006-291X. 450(4), p. 1525–1530. doi: 10.1016/j.bbrc.2014.07.036.
  • Shi, Jihua; Scholz, Hanne ; Huitfeldt, Henrik & Line, Pål Dag (2014). The effect of hepatic progenitor cells on experimental hepatocellular carcinoma in the regenerating liver. Scandinavian Journal of Gastroenterology. ISSN 0036-5521. 49(1), p. 99–108. doi: 10.3109/00365521.2013.854406.
  • Sahraoui, Afaf; Kloster-Jensen, Kristine; Ueland, Thor; Korsgren, Olle; Foss, Aksel & Scholz, Hanne (2014). Anakinra and tocilizumab enhance survival and function of human islets during culture: Implications for clinical islet transplantation. Cell Transplantation. ISSN 0963-6897. 23(10), p. 1199–1211. doi: 10.3727/096368913X667529.
  • Lekva, Tove; Bollerslev, Jens; Sahraoui, Afaf; Scholz, Hanne Bjørnson; Bøyum, Hege Hestetun & Evang, Johan Arild [Show all 9 contributors for this article] (2013). Thioredoxin Interacting Protein Is a Potential Regulator of Glucose and Energy Homeostasis in Endogenous Cushing's Syndrome. PLOS ONE. ISSN 1932-6203. 8(5). doi: 10.1371/journal.pone.0064247.
  • Shi, Jihua; Liu, Shuzheng; Wierød, Lene; Scholz, Hanne Bjørnson; Anmarkrud, Jarl Andreas & Huitfeldt, Henrik [Show all 8 contributors for this article] (2013). RAF-targeted therapy for hepatocellular carcinoma in the regenerating liver. Journal of Surgical Oncology. ISSN 0022-4790. 107(4), p. 393–401. doi: 10.1002/jso.23224.
  • Yu, Y; Hanssen, Kristian Folkvord; Kalyanaraman, V; Chirindel, A; Jenkins, AJ & Nankervis, AJ [Show all 19 contributors for this article] (2012). Reduced soluble receptor for advanced glycation end-products (sRAGE) scavenger capacity precedes pre-eclampsia in Type 1 diabetes. BJOG: An International Journal of Obstetrics and Gynaecology. ISSN 1470-0328. 119(12), p. 1512–1520. doi: 10.1111/j.1471-0528.2012.03463.x.
  • Basu, Arpita; Alaupovic, Petar; Wu, Mingyuan; Jenkins, Alica J.; Yu, Yongxin & Nankervis, Alison J. [Show all 19 contributors for this article] (2012). Plasma Lipoproteins and Preeclampsia in Women with Type 1 Diabetes: A Prospective Study. Journal of Clinical Endocrinology and Metabolism (JCEM). ISSN 0021-972X. 97(5), p. 1752–1762. doi: 10.1210/jc.2011-3255.
  • Azar, Madona; Basu, Arpita; Jenkins, Alica J.; Nankervis, Alison J.; Hanssen, Kristian Folkvord & Scholz, Hanne Bjørnson [Show all 12 contributors for this article] (2011). Serum Carotenoids and Fat-Soluble Vitamins in Women With Type 1 Diabetes and Preeclampsia A longitudinal study. Diabetes Care. ISSN 0149-5992. 34(6), p. 1258–1264. doi: 10.2337/dc10-2145.
  • Andersen, Geir Øystein; Ueland, Thor; Knudsen, Eva Cecilie; Scholz, Hanne Bjørnson; Yndestad, Arne & Sahraoui, Afaf [Show all 12 contributors for this article] (2011). Activin A Levels Are Associated With Abnormal Glucose Regulation in Patients With Myocardial Infarction Potential Counteracting Effects of Activin A on Inflammation. Diabetes. ISSN 0012-1797. 60(5), p. 1544–1551. doi: 10.2337/db10-1493.
  • Lund, Tormod; Korsgren, Olle; Aursnes, Ingrid Augusta Stølen; Scholz, Hanne Bjørnson & Foss, Aksel (2010). Sustained Reversal of Diabetes Following Islet Transplantation to Striated Musculature in the Rat. Journal of Surgical Research. ISSN 0022-4804. 160(1), p. 145–154. doi: 10.1016/j.jss.2008.11.009.
  • Lund, Tormod; Mangsbo, Sara; Scholz, Hanne Bjørnson; Gjorstrup, P.; Tötterman, Thomas H. & Korsgren, Olle [Show all 7 contributors for this article] (2010). Resolvin E1 Reduces Proinflammatory Markers in Human Pancreatic Islets in vitro. Experimental and clinical endocrinology & diabetes. ISSN 0947-7349. 18(4), p. 237–244. doi: 10.1055/s-0029-1241825.
  • Ueland, Thor; Fougner, Stine Lyngvi; Godang, Kristin; Lekva, Tove; Schurgers, LJ & Scholz, Hanne Bjørnson [Show all 10 contributors for this article] (2010). Associations between Body Composition, Circulating Interleukin-1 Receptor Antagonist, Osteocalcin, and Insulin Metabolism in Active Acromegaly. Journal of Clinical Endocrinology and Metabolism (JCEM). ISSN 0021-972X. 95(1), p. 361–368. doi: 10.1210/jc.2009-0422.
  • Yu, Y; Jenkins, AJ; Nankervis, AJ; Hanssen, Kristian Folkvord; Scholz, Hanne Bjørnson & Henriksen, Tore [Show all 21 contributors for this article] (2009). Anti-angiogenic factors and pre-eclampsia in type 1 diabetic women. Diabetologia. ISSN 0012-186X. 52(1), p. 160–168. doi: 10.1007/s00125-008-1182-x.
  • Scholz, Hanne Bjørnson; Lund, Tormod; Dahle, Maria Krudtaa; Collins, Jon L.; Ole, Korsgren & Wang, Jacob Edward [Show all 7 contributors for this article] (2009). The synthetic liver X receptor agonist GW3965 reduces tissue factor and inflammatory responses in human islets in vitro. Diabetologia. ISSN 0012-186X. 52(7), p. 1352–1362. doi: 10.1007/s00125-009-1366-z.
  • Lund, Tormod; Korsgren, Olle; Aursnes, Ingrid Augusta Stølen; Scholz, Hanne Bjørnson & Foss, Aksel (2008). Sustained Reversal of Diabetes Following Islet Transplantation to Striated Musculature in the Rat. Journal of Surgical Research. ISSN 0022-4804.
  • Lund, Tormod; Fosby, Bjarte; Scholz, Hanne Bjørnson; Korsgren, Olle & Foss, Aksel (2008). Glucocorticoids reduce proinflammatory cytokines and tissue factor in vitro and improve function of transplanted human islets in vivo. Transplant International. ISSN 0934-0874. 21(7), p. 669–678.
  • Halvorsen, Bente ; Wæhre, Torgun; Scholz, Hanne; Damås, Jan Kristian; Yndestad, Arne & Aukrust, Pål (2006). Role of interleukin-10 in atherogenesis and plaque stabilization. Future Cardiology. ISSN 1479-6678. 2(1), p. 75–83.
  • Sandberg, Wiggo Johan; Yndestad, Arne; Øie, Erik; Smith, Camilla; Ueland, Thor & Ovchinnikova, Olga [Show all 17 contributors for this article] (2006). Enhanced T-cell expression of RANK ligand in acute coronary syndrome - Possible role in plaque destabilization. Arteriosclerosis, Thrombosis and Vascular Biology. ISSN 1079-5642. 26.
  • Smith, Camilla; Damås, Jan Kristian; Otterdal, Kari; Øie, Erik; Sandberg, Wiggo Johan & Yndestad, Arne [Show all 15 contributors for this article] (2006). Increased levels of neutrophil-activating peptide-2 in acute coronary syndromes - Possible role of platelet-mediated vascular inflammation. Journal of the American College of Cardiology. ISSN 0735-1097. 48(8), p. 1591–1599.
  • Halvorsen, Bente ; Wæhre, Torgun; Schulz, Hanne; Clausen, Ole Petter; Von der Thusen, JH & Muller, Fredrik [Show all 13 contributors for this article] (2005). Interleukin-10 enhances the oxidized LDL-induced foam cell formation of macrophages by antiapoptotic mechanisms. Journal of Lipid Research. ISSN 0022-2275. 46.
  • Scholz, Hanne; Sandberg, Wiggo Johan; Damås, Jan Kristian; Smith, Camilla; Gullestad, Lars & Andreassen, Arne K. [Show all 9 contributors for this article] (2005). Enhanced plasma levels of LIGHT in unstable angina: possible pathogenic role in foam cell formation and thrombosis. Circulation. ISSN 0009-7322. 114(14), p. 2121–2129.
  • Scholz, Hanne; Aukrust, Pål; Damås, Jan Kristian; Tonstad, Serena; Sagen, Ellen Lund & Kolset, Svein Olav [Show all 9 contributors for this article] (2004). 8-isoprostane increases scavenger receptor A and matrix metalloproteinase activity in THP-1 macrophages, resulting in long-lived foam cells. European Journal of Clinical Investigation. ISSN 0014-2972. 34(7), p. 451–458.
  • Smith, Camilla; Yndestad, Arne; Halvorsen, Bente; Ueland, Thor; Wæhre, Torgun & Otterdal, Kari [Show all 12 contributors for this article] (2004). Potential anti-inflammatory role of activin A in acute coronary syndromes. Journal of the American College of Cardiology. ISSN 0735-1097. 44, p. 369–375.
  • Holven, Kirsten Bjørklund; Halvorsen, Bente; Schulz, Hanne; Aukrust, Pål; Ose, Leiv & Nenseter, Marit Sofie (2003). Expression of matrix metalloproteinase-9 in mononuclear cells of hyperhomocysteinaemic subjects. European Journal of Clinical Investigation. ISSN 0014-2972. 33, p. 555–560.
  • Holven, Kirsten Bjørklund; Scholz, Hanne; Halvorsen, Bente; Aukrust, Pål; Ose, Leiv & Nenseter, Marit Sofie (2003). Hyperhomocysteinaemic subjects have enhanced expression of lectin-like oxidized LDL receptor-1 in mononuclear cells. Journal of Nutrition. ISSN 0022-3166. 133(11), p. 3588–3591.
  • Scholz, Hanne; Yndestad, Arne; Damås, Jan Kristian; Wæhre, Torgun; Tonstad, Serena & Aukrust, Pål [Show all 7 contributors for this article] (2003). 8-Isoprostane increases expression of interleukin-8 in human macrophages through activation of mitogen-activated protein kinases. Cardiovascular Research (CVR). ISSN 0008-6363. 59(4), p. 945–954.
  • Schulz, Hanne; Langvik, T. A.; Sagen, Ellen Lund; Smith, Jørgen A.; Ahmadi, N. & Hall, Christian (2001). Radioimmunoassay for N- terminal probrain natriuretic peptide in human plasma. Scandinavian Journal of Clinical and Laboratory Investigation. ISSN 0036-5513. 61, p. 33–42.

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  • Scholz, Hanne & Ræder, Helge (2023). Response to Comment on Carrasco et al. Spatial Environment Affects HNF4A Mutation-Specific Proteome Signatures and Cellular Morphology in hiPSC-Derived β-Like Cells. Diabetes 2022;71:862-869. Diabetes. ISSN 0012-1797. 72(5). doi: 10.2337/dbi23-0007.
  • Legøy, Thomas Aga; Mathisen, Andreas Frøslev; Scholz, Hanne; Paulo, Joao; Ræder, Helge & Ghila, Luiza Mihaela [Show all 7 contributors for this article] (2022). Molecular mechanisms affecting islet like cell fate acquisition in differentiating iPSC derived β-like cells”.
  • Ghila, Luiza Mihaela; Furuyama, Kenichiro; Grey, Shane T.; Scholz, Hanne & Chera, Simona (2022). Editorial: Beta-Cell Fate: From Gene Circuits to Disease Mechanisms. Frontiers in Genetics. ISSN 1664-8021. 13. doi: 10.3389/fgene.2022.822440.
  • Abadpour, Shadab; Niemi, Essi Maria; Strid Orrhult, Linnea; Parreiras Nogueira, Liebert; Haugen, Håvard Jostein & Josefsen, Dag [Show all 10 contributors for this article] (2021). 307.7: 3D Bioprinting of Functional Islets With Adipose-derived Stromal Cells in an Alginate/Nanocellulose Scaffold. Transplantation. ISSN 0041-1337. p. S25–S25. doi: 10.1097/01.tp.0000804424.50335.7e.
  • Wang, Chencheng; Abadpour, Shadab; Aizenshtadt, Alexandra; Chera, Simona; Ghila, Luiza Mihaela & Ræder, Helge [Show all 7 contributors for this article] (2021). Glucose during in vitro pancreatic beta cells regeneration: friends or for?
  • Wang, Chencheng; Abadpour, Shadab; Aizenshtadt, Alexandra; Chera, Simona; Ghila, Luiza Mihaela & Ræder, Helge [Show all 7 contributors for this article] (2021). 402.2: High Glucose Concentration Increases KATP Channel Activity but Suppresses Mitochondrial Respiration Ability in Insulin-producing Cells Regenerated From Stem Cells. Transplantation. ISSN 0041-1337. p. S27–S27. doi: 10.1097/01.tp.0000804436.14096.44.
  • Olsen, Christine; Scholz, Hanne; Wilson, Steven Ray Haakon & Lundanes, Elsa (2020). Towards online reduction and protein digestion of secreted proteins from pancreatic islets of Langerhans related to diabetes mellitus type I.
  • Shi, Jihua; Scholz, Hanne Bjørnson & Line, Pål Dag (2012). "Recurrence" of Hepatocellular Carcinoma after Surgery: Experimental Evidence for Participation of Hepatic Progenitor Cells. Liver transplantation. ISSN 1527-6465. 18, p. S160–S160.
  • Wu, M.; Du, M; Jenkins, A.; Nankervis, AJ; Hanssen, Kristian Folkvord & Scholz, Hanne Bjørnson [Show all 18 contributors for this article] (2010). CIRCULATING CYTOKINES PREDICT PRE-ECLAMPSIA IN TYPE 1 DIABETES MELLITUS. Journal of Investigative Medicine. ISSN 1081-5589. 58(2), p. 392–392.
  • Azar, Madona; Lyons, Timothy J.; Wu, Mingyuan; Jenkins, Alicia; Scholz, Hanne & Aston, Christopher E. [Show all 13 contributors for this article] (2010). VITAMIN D DEFICIENCY AND PREECLAMPSIA IN PREGNANT WOMEN WITH TYPE 1 DIABETES MELLITUS. Journal of Investigative Medicine. ISSN 1081-5589. 58(2), p. 385–385.
  • Holven, Kirsten Bjørklund; Halvorsen, Bente; Schulz, Hanne; Aukrust, Pål; Ose, Leiv & Nenseter, Marit Sofie (2003). Enhanced expression of lectin-like oxidized LDL receptor-1 (LOX-1) in peripheral blood mononuclear cells of hyperhomosysteinemic subjects; effect of folic acid treatment.
  • Schulz, Hanne; Yndestad, Arne; Aukrust, Pål; Hall, Christian & Halvorsen, Bente (2002). 8-iso-prostaglandin F2a stimulates interleukin-8 expression in human THP-1 derived macrophages.
  • Schulz, Hanne; Halvorsen, Bente & Hall, Christian (2001). 8-iso-Prostaglandin F2alpha reduces productin of TIMP-1 in human macrophages (THP-1 cells). A potential role of 8-iso-prostaglandin F2alpha in plaque rupture.
  • Kwak, Dongho; Jensenius, Alexander Refsum; Danielsen, Anne; Scholz, Hanne & Olsen, Petter Angell (2023). Music for cells? Rhythmic mechanical stimulations of cell cultures. Universitetet i Oslo. Full text in Research Archive
  • Scholz, Hanne (2006). Human macrophage function in the pathogenesis of atherosclerosis. Unipub forlag. ISSN 82-8072-213-0.

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Published Mar. 13, 2018 3:31 PM - Last modified May 18, 2021 12:12 PM