Latest publications from HTH - Hybrid Technology Hub

Latest 100 registrations from Cristin (Current Research Information System in Norway).

  • Abadpour, Shadab; Aizenshtadt, Aleksandra; Olsen, Petter Angell; Shoji, Kayoko; Wilson, Steven Ray Haakon; Krauss, Stefan & Scholz, Hanne (2020). Pancreas-on-a-Chip Technology for Transplantation Applications. Current Diabetes Reports.  ISSN 1534-4827.  20(12) . doi: 10.1007/s11892-020-01357-1
  • Perdreau-Dahl, Harmonie; Progida, Cinzia; Barfeld, Stefan Jörg; Guldsten, Hanne; Thiede, Bernd; Arntzen, Magnus Øverlie; Bakke, Oddmund; Mills, Ian Geoffrey; Krauss, Stefan & Morth, Jens Preben (2020). Sjögren syndrome/scleroderma autoantigen 1 is a direct Tankyrase binding partner in cancer cells. Communications Biology.  ISSN 2399-3642.  3(1) . doi: 10.1038/s42003-020-0851-2
  • Tsjokajev, Ahmad; Røberg-Larsen, Hanne; Wilson, Steven Ray Haakon; Anne Berit Dyve, Lingelem; Skotland, Tore; Sandvig, Kirsten & Lundanes, Elsa (2020). Mass spectrometry-based measurements of cyclic adenosine monophosphate in cells, simplified using reversed phase liquid chromatography with a polar characterized stationary phase. Journal of chromatography. B.  ISSN 1570-0232.  1160:122384, s 1- 6 . doi: 10.1016/j.jchromb.2020.122384
  • Legøy, Thomas Aga; Vethe, Heidrun; Abadpour, Shadab; Strand, Berit Løkensgard; Scholz, Hanne; Paulo, Joao A.; Ræder, Helge; Ghila, Luiza & Chera, Simona (2020). Encapsulation boosts islet-cell signature in differentiating human induced pluripotent stem cells via integrin signalling. Scientific Reports.  ISSN 2045-2322.  15(10) . doi: 10.1038/s41598-019-57305-x Full text in Research Archive.
  • Legøy, Thomas Aga; Mathisen, Andreas Frøslev; Salim, Zaidon; Vethe, Heidrun; Bjørlykke, Yngvild; Abadpour, Shadab; Paulo, Joao; Scholz, Hanne; Ræder, Helge; Ghila, Luiza & Chera, Simona (2020). In vivo environment swiftly restricts human pancreatic progenitors toward mono-hormonal identity via a HNF1A/HNF4A mechanism. Frontiers in Cell and Developmental Biology.  ISSN 2296-634X.  8:109, s 1- 14 . doi: 10.3389/fcell.2020.00109 Full text in Research Archive.
  • Waaler, Jo; Leenders, Ruben G G; Sowa, Sven T.; Brinch, Shoshy Alam; Lycke, Eric Maximilian; Nieczypor, Piotr; Aertssen, Sjoerd; Murthy, Sudarshan; Galera-Prat, Albert; Damen, Eddy; Wegert, Anita; Nazaré, Marc; Lehtiö, Lari & Krauss, Stefan (2020). Preclinical lead optimization of a 1,2,4-triazole based tankyrase inhibitor. Journal of Medicinal Chemistry.  ISSN 0022-2623.  63(13), s 6834- 6846 . doi: 10.1021/acs.jmedchem.0c00208
  • Berishvili, Ekaterine; Kaiser, Laurent; Cohen, Marie; Berney, Thierry; Scholz, Hanne Bjørnson; Fløisand, Yngvar & Mattsson, Jonas (2020). Treatment of COVID-19 Pneumonia: the Case for Placenta-derived Cell Therapy. Stem Cell Reviews and Reports.  ISSN 1550-8943.  s 1- 8 . doi: 10.1007/s12015-020-10004-x Full text in Research Archive.
  • Frafjord, Astri; Skarshaug, Renate; Hammarström, Clara Louise; Stankovic, Branislava; Dorg, Linda Trobe; Aamodt, Henrik; Woldbæk, Per R; Helland, Åslaug; Brustugun, Odd Terje; Øynebråten, Inger & Corthay, Alexandre (2020). Antibody combinations for optimized staining of macrophages in human lung tumours. Scandinavian Journal of Immunology.  ISSN 0300-9475.  92:e12889(1), s 1- 24 . doi: 10.1111/sji.12889 Full text in Research Archive.
  • Xiang, Yangfei; Tanaka, Yoshiaki; Patterson, Benjamin; Hwang, Sun-Min; Hysolli, Eriona; Cakir, Bilal; Kim, Kun-Yong; Wang, Wanshan; Kang, Young-Jin; Clement, Ethan; Zhong, Mei; Lee, Sang-Hun; Cho, Yes Sook; Patra, Prabir; Sullivan, Gareth; Weissman, Sherman & Park, In-Hyun (2020). Dysregulation of BRD4 Function Underlies the Functional Abnormalities of MeCP2 Mutant Neurons. Molecular Cell.  ISSN 1097-2765.  79, s 1- 15 . doi: doi.org/10.1016/j.molcel.2020.05.016 Full text in Research Archive. Show summary
  • Waaler, Jo; Mygland, Line; Tveita, Anders Aune; Strand, Martin Frank; Solberg, Nina; Olsen, Petter Angell; Aizenshtadt, Aleksandra; Fauskanger, Marte; Lund, Kaja; Brinch, Shoshy Alam; Lycke, Max; Dybing, Elisabeth; Nygaard, Vegard; Bøe, Sigurd; Heintz, Karen Marie; Hovig, Eivind; Hammarström, Clara Louise; Corthay, Alexandre & Krauss, Stefan (2020). Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models. Communications Biology.  ISSN 2399-3642.  3(196) . doi: 10.1038/s42003-020-0916-2
  • Amini, Maryam; Niemi, Essi; Hisdal, Jonny; Kalvøy, Håvard; Tronstad, Christian; Scholz, Hanne; Rosales, Antonio & Martinsen, Ørjan Grøttem (2020). Monitoring the quality of frozen-thawed venous segments using bioimpedance spectroscopy. Physiological Measurement.  ISSN 0967-3334. . doi: 10.1088/1361-6579/ab85b7
  • Tanaka, Yoshiaki; Cakir, Bilal; Xiang, Yangfei; Sullivan, Gareth & Park, In-Hyun (2020). Synthetic Analyses of Single-Cell Transcriptomes from Multiple Brain Organoids and Fetal Brain. Cell reports.  ISSN 2211-1247. . doi: https://doi.org/10.1016/j.celrep.2020.01.038 Full text in Research Archive.
  • Zhong, Xiangfu; Planas, Albert Pla & Rayner, Simon (2019). Jasmine: a Java pipeline for isomiR characterization in miRNA-Seq data. Bioinformatics.  ISSN 1367-4803. . doi: 10.1093/bioinformatics/btz806 Full text in Research Archive. Show summary
  • Zhong, Xiangfu; Heinicke, Fatima; Lie, Benedicte Alexandra & Rayner, Simon (2019). Accurate Adapter Information Is Crucial for Reproducibility and Reusability in Small RNA Seq Studies. Non-coding RNA.  ISSN 2311-553X. . doi: 10.3390/ncrna5040049 Full text in Research Archive.
  • Korsgren, Olle & Scholz, Hanne (2019). Cellular therapies in preclinical and clinical islet transplantation: Mesenchymal stem cells., In Giuseppe Orlando (ed.),  Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas.  Elsevier.  ISBN 9780128148334.  Chapter 61.
  • von Zur-Mühlen, Bengt; Scholz, Hanne; Hellman, Jarl; Korsgren, Olle & Lundgren, Torbjørn (2019). Treating diabetes with islet transplantation:Lessons learnt from the Nordic network for clinical islet transplantation., In Giuseppe Orlando (ed.),  Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas.  Elsevier.  ISBN 9780128148334.  Chapter 48.
  • Legøy, Thomas Aga; Ghila, Luiza; Vethe, Heidrun; Abadpour, Shadab; Mathisen, Andreas Frøslev; Paulo, Joao A.; Scholz, Hanne; Ræder, Helge & Chera, Simona (2019). In vivo hyperglycemia exposure elicits distinct period-dependent effects on human pancreatic progenitor differentiation, conveyed by oxidative stress. Acta Physiologica.  ISSN 1748-1708.  23:247577, s 1- 16 . doi: 10.1111/apha.13433 Full text in Research Archive.
  • Wilson, Steven Ray Haakon; Olsen, Christine & Lundanes, Elsa (2019). Nano liquid chromatography columns. The Analyst.  ISSN 0003-2654.  144(24), s 7090- 7104 . doi: 10.1039/c9an01473j Full text in Research Archive.
  • Lin, Ann; Skottvoll, Frøydis Sved; Rayner, Simon; Pedersen-Bjergaard, Stig; Sullivan, Gareth; Krauss, Stefan; Wilson, Steven Ray Haakon & Harrison, Sean (2019). 3D cell culture models and organ-on-a-chip: Meet separation science and mass spectrometry. Electrophoresis.  ISSN 0173-0835.  41, s 56- 64 . doi: 10.1002/elps.201900170 Full text in Research Archive.
  • Vogt, Henrik; Green, Sara; Ekstrøm, Claus Thorn & Brodersen, John (2019). How precision medicine and screening with big data could increase overdiagnosis. BMJ. British Medical Journal.  ISSN 1756-1833.  366 . doi: 10.1136/bmj.l5270 Full text in Research Archive.
  • Bogdanova, Mariia; Zabirnyk, Arsenii; Malashicheva, Anna; Zihlavnikova, Katarina; Karlsen, Tommy Aleksander; Kaljusto, Mari-Liis; Kvitting, John Peder Escobar; Dissen, Erik; Sullivan, Gareth; Kostareva, Anna; Stensløkken, Kåre-Olav; Rutkovskiy, Arkady & Vaage, Ingvar Jarle (2019). Interstitial cells in calcified aortic valves have reduced differentiation potential and stem cell-like properties. Scientific Reports.  ISSN 2045-2322.  9:12934, s 1- 13 . doi: 10.1038/s41598-019-49016-0 Full text in Research Archive. Show summary
  • MacLean, Evan L.; Wilson, Steven Ray Haakon; Martin, W. Lance; Davis, John; Nazarloo, Hossein P. & Carter, C. Sue (2019). Challenges for measuring oxytocin: The blind men and the elephant?. Psychoneuroendocrinology.  ISSN 0306-4530.  107, s 225- 231 . doi: 10.1016/j.psyneuen.2019.05.018 Full text in Research Archive.
  • Hvinden, Ingvild Comfort; Berg, Henriette Engen; Sachse, Daniel; Skaga, Erlend; Skottvoll, Frøydis Sved; Lundanes, Elsa; Sandberg, Cecilie; Vik-Mo, Einar O.; Rise, Frode & Wilson, Steven Ray Haakon (2019). Nuclear Magnetic Resonance Spectroscopy to Identify Metabolite Biomarkers of Nonresponsiveness to Targeted Therapy in Glioblastoma Tumor Stem Cells. Journal of Proteome Research.  ISSN 1535-3893.  18(5), s 2012- 2020 . doi: 10.1021/acs.jproteome.8b00801
  • Tao, Xiao-Yan; Li, Mu-Li; Wang, Qian; Baima, Ciwang; Hong, Mei; Li, Wei; Wu, Yong-Biao; Li, Yan-Rong; Zhao, Yu-Min; Rayner, Simon & Zhu, Wu-Yang (2019). The reemergence of human rabies and emergence of an Indian subcontinent lineage in Tibet, China. PLoS Neglected Tropical Diseases.  ISSN 1935-2727.  13(1) . doi: 10.1371/journal.pntd.0007036 Full text in Research Archive. Show summary
  • Brennecke, Philip; Rasina, Dace; Aubi Catevilla, Oscar; Herzog, Katja; Landskron, Johannes; Cautain, Bastien; Vicente, Francisca; Quintana, Jordi; Mestres, Jordi; Stechmann, Bahne; Ellinger, Bernhard; Brea, Jose; Kolanowski, Jacek L.; Pilarski, Radosław; Orzáez, Mar; Pineda-Lucena, Antonio; Laraia, Luca; Nami, Faranak; Zielenkiewicz, Piotr; Paruch, Kamil; Hansen, Espen; von Kries, Jens P.; Neuenschwander, Martin; Specker, Edgar; Bartunek, Petr; Šímová, Šárka; Leśnikowski, Zbigniew; Krauss, Stefan; Lehtiö, Lari; Bilitewski, Ursula; Brönstrup, Mark; Tasken, Kjetil; Jirgensons, Aigars; Lickert, Heiko; Clausen, Mads H.; Andersen, Jeanette hammer; Vicent, Maria J.; Genilloud, Olga; Martinez, Aurora; Nazaré, Marc; Fecke, Wolfgang & Gribbon, Philip (2019). EU-OPENSCREEN: A novel collaborative approach to facilitate chemical biology. SLAS Discovery.  ISSN 2472-5552.  24(3), s 398- 413 . doi: 10.1177/2472555218816276 Full text in Research Archive.
  • Solberg, Nina; Melheim, Maria; Strand, Martin Frank; Olsen, Petter Angell & Krauss, Stefan (2019). MEK Inhibition Induces Canonical WNT Signaling through YAP in KRAS Mutated HCT-15 Cells, and a Cancer Preventive FOXO3/FOXM1 Ratio in Combination with TNKS Inhibition. Cancers.  ISSN 2072-6694.  11(2), s 1- 19 . doi: 10.3390/cancers11020164 Full text in Research Archive.
  • Solberg, Nina Therese; Waaler, Jo; Iversen, Kaja Lund; Mygland, Line; Olsen, Peter Angell & Krauss, Stefan (2018). TANKYRASE Inhibition Enhances the Antiproliferative Effect of PI3K and EGFR Inhibition, Mutually Affecting β-CATENIN and AKT Signaling in Colorectal Cancer. Molecular Cancer Research.  ISSN 1541-7786.  16(3), s 1541 . doi: 10.1158/1541-7786.MCR-17-0362
  • Bogdanova, Mariia; Kostina, Aleksandra; Zihlavnikova, Katarina; Zabirnyk, Arsenii; Malashicheva, Anna; Stensløkken, Kåre-Olav; Sullivan, Gareth; Kaljusto, Mari-Liis; Kvitting, John Peder Escobar; Kostareva, Anna; Vaage, Ingvar Jarle & Rutkovskiy, Arkady (2018). Inflammation and Mechanical Stress Stimulate Osteogenic Differentiation of Human Aortic Valve Interstitial Cells. Frontiers in Physiology.  ISSN 1664-042X.  9 . doi: 10.3389/fphys.2018.01635 Full text in Research Archive.
  • Schive, Simen Walberg; Fjukstad, Ragnhild; Josefsen, Dag; Katavic, Marina; Abadpour, Shadab; Gullestad, Hans Petter; Kvalheim, Gunnar & Scholz, Hanne (2018). Automated isolation and expansion of human adipose tissuederived stem cells for a seamless translation into clinical trials. CellR4 (repair, Replacement, Regenerative&Reprogramming.  ISSN 2329-7042.  6(2), s e2519
  • Kim, Kun-Yong; Tanaka, Yoshiaki; Su, Juan; Cakir, Bilal; Xiang, Yangfei; Patterson, Benjamin; Ding, Junjun; Jung, Yong-Wook; Kim, Ji-Hyun; Hysolli, Eriona; Lee, Haelim; Dajani, Rana; Kim, Jonghwan; Zhong, Mei; Lee, Jeong-Heon; Skalnik, David; Lim, Jeong Mook; Sullivan, Gareth; Wang, Jianlong & Park, In-Hyun (2018). Uhrf1 regulates active transcriptional marks at bivalent domains in pluripotent stem cells through Setd1a. Nature Communications.  ISSN 2041-1723.  9:2583, s 1- 13 . doi: 10.1038/s41467-018-04818-0 Full text in Research Archive. Show summary
  • Pisal, Rishikaysh V.; Suchánek, Jakub; Siller, Richard; Soukup, Tomáš; Hrebíková, Hana; Bezrouk, Ales; Kunke, David; Mičuda, Stanislav; Filip, Stanislav; Sullivan, Gareth & Mokrý, Jaroslav (2018). Directed reprogramming of comprehensively characterized dental pulp stem cells extracted from natal tooth. Scientific Reports.  ISSN 2045-2322.  8(1) . doi: 10.1038/s41598-018-24421-z Full text in Research Archive.
  • Abadpour, Shadab; Halvorsen, Bente; Sahraoui, Afaf; Korsgren, Olle; Aukrust, Pål & Scholz, Hanne (2018). Interleukin-22 reverses human islet dysfunction and apoptosis triggered by hyperglycemia and LIGHT. Journal of Molecular Endocrinology.  ISSN 0952-5041.  60(3), s 171- 183 . doi: 10.1530/JME-17-0182
  • Solberg, Nina T.; Waaler, Jo; Lund, Kaja; Mygland, Line; Olsen, Petter A. & Krauss, Stefan (2017). TANKYRASE inhibition enhances the antiproliferative effect of PI3K and EGFR inhibition, mutually affecting β-CATENIN and AKT signaling in colorectal cancer. Molecular Cancer Research.  ISSN 1541-7786.  16(3), s 543- 553 . doi: 10.1158/1541-7786.MCR-17-0362
  • Schive, Simen Walberg; Mirlashari, Mohammad Reza; Hasvold, Grete; Wang, Mengyu; Josefsen, Dag; Gullestad, Hans Petter; Korsgren, Olle; Foss, Aksel; Kvalheim, Gunnar & Scholz, Hanne (2017). Human Adipose-Derived Mesenchymal Stem Cells Respond to Short-Term Hypoxia by Secreting Factors Beneficial for Human Islets in Vitro and Potentiate Antidiabetic Effect in Vivo. Cell Medicine.  ISSN 2155-1790.  9, s 103- 116 . doi: 10.3727/215517917X693401
  • Lund, Kaja; Olsen, Cathrine Elisabeth; Wong, Judith Jing Wen; Olsen, Petter Angell; Solberg, Nina Therese; Høgset, Anders; Krauss, Stefan & Selbo, Pål Kristian (2017). 5-FU resistant EMT-like pancreatic cancer cells are hypersensitive to photochemical internalization of the novel endoglin-targeting immunotoxin CD105-saporin. Journal of Experimental & Clinical Cancer Research.  ISSN 1756-9966.  36, s 1- 18 . doi: 10.1186/s13046-017-0662-6
  • Anumala, Upendra Rao; Waaler, Jo; Nkizinkiko, Yves; Ignatev, Alexander; Lazarow, Katina; Lindemann, Peter; Olsen, Petter Angell; Murthy, Sudarshan; Obaji, Ezeogo; Majouga, Alexander G; Leonov, Sergey; von Kries, Jens Peter; Lehtiö, Lari; Krauss, Stefan & Nazare, Marc (2017). Discovery of a Novel Series of Tankyrase Inhibitors by a Hybridization Approach. Journal of Medicinal Chemistry.  ISSN 0022-2623.  60(24), s 10013- 10025 . doi: 10.1021/acs.jmedchem.7b00883
  • Sullivan, Gareth & Siller, Richard (2017). Simple and rapid screen for human pluripotent stem cell endoderm differentiation potential.. Current protocols in stem cell biology.  ISSN 1941-7322.  43, s 1G.7.1- 1G.7.23 . doi: 10.1002/cpsc.36

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  • Skottvoll, Frøydis Sved; Harrison, Sean; Hansen, Frederik; Pedersen-Bjergaard, Stig; Sullivan, Gareth; Bogen, Inger Lise; Lundanes, Elsa & Wilson, Steven Ray Haakon (2020). Liver mini-organ analyses using liquid chromatography mass spectrometry. Show summary
  • Boger, Ida Caroline Sneis; Nerem, Elisabeth; Skottvoll, Frøydis Sved; Harrison, Sean; Sullivan, Gareth; Lundanes, Elsa; Bogen, Inger Lise & Wilson, Steven Ray Haakon (2020). Determination of liver organoid-induced drug metabolites using liquid chromatography-mass spectrometry (LC-MS)”. Show summary
  • Mrša, Ago; Skottvoll, Frøydis Sved; Harrison, Sean; Lundanes, Elsa; Sullivan, Gareth & Wilson, Steven Ray Haakon (2020). Miniaturized liquid chromatography systems for small molecule analysis of organoids. Show summary
  • Olsen, Christine; Scholz, Hanne; Wilson, Steven Ray Haakon & Lundanes, Elsa (2020). Towards online reduction and protein digestion of secreted proteins from pancreatic islets of Langerhans related to diabetes mellitus type I. Show summary
  • Chollet, Maria Eugenia; Andersen, Elisabeth; Skarpen, Ellen; Mowinckel, Marie-Christine; Stavik, Benedicte; Sullivan, Gareth & Sandset, Per Morten (2019). FVII: A human pluripotent stem cell derived hepatocyte model with potential therapeutic applications.. Research and Practice in Thrombosis and Haemostasis.  ISSN 2475-0379.  3
  • Vogt, Henrik (2019, 05. september). In This Doctor’s Office, a Physical Exam Like No Other.  New York Times.
  • Vogt, Henrik (2019, 20. september). De sidste raske.  Weekendavisen.
  • Vogt, Henrik (2019). Precision medicine and the Return of the Art of Medicine.
  • Vogt, Henrik (2019). The precision paradox - how personalized medicine may create more uncertainty in medicine.
  • Pahle, Andreas & Vogt, Henrik (2019). Physician’s Perspective - Using Precision Medicine Research in Practice for Patients’ Benefit.
  • Mrša, Ago; Boger, Ida Caroline Sneis; Nerem, Elisabeth; Skottvoll, Frøydis Sved; Harrison, Sean; Lundanes, Elsa; Sullivan, Gareth; Bogen, Inger Lise & Wilson, Steven Ray Haakon (2019). Studying organoid drug metabolism using UHPLC/nanoLC-MS. Show summary
  • Skottvoll, Frøydis Sved; Boger, Ida Caroline Sneis; Harrison, Sean; Nerem, Elisabeth; Bogen, Inger Lise; Sullivan, Gareth & Wilson, Steven Ray Haakon (2019). LC-MS approaches to liver organoid analyses. Show summary
  • Vogt, Henrik; Solbakk, Jan Helge & Hofmann, Bjørn Morten (2019). The precision paradox in personalized medicine: How can uncertainty be reduced when statistics do not apply?.
  • Vethe, Heidrun; Legøy, Thomas Aga; Abadpour, Shadab; Strand, Berit Løkensgard; Scholz, Hanne; Paulo, Joao A.; Ræder, Helge; Ghila, Luiza & Chera, Simona (2019). Encapsulation boosts islet-cell signature in differentiating human induced pluripotent stem cells via integrin signalling. bioRxiv - the preprint server for biology. . doi: 10.1101/791442
  • Vehus, Tore; Wilson, Steven Ray Haakon; Lundanes, Elsa; Krauss, Stefan; Halvorsen, Trine Grønhaug & Morth, Jens Preben (2018). Nano Liquid Chromatography-Tandem Mass Spectrometry Platforms for Determination of Low Abundant Wnt/Beta-Catenin Proteins in Cancer Research. Series of dissertations submitted to the Faculty of Mathematics and Natural Sciences, University of Oslo.. 1962.
  • Brandtzaeg, Ole Kristian; Wilson, Steven Ray Haakon; Lundanes, Elsa; Reubsaet, Leon; Krauss, Stefan & Martinsen, Ørjan Grøttem (2018). Online sample Preparation Platforms for Targeted Nano Liquid Chromatography Mass Spectrometry Bioanalysis. Series of dissertations submitted to the Faculty of Mathematics and Natural Sciences, University of Oslo.. 1968.
  • Impellizzeri, Agata Antonina Rita; Szabo, Attila; Fjerdingstad, Hege Brincker; Sullivan, Gareth; Glover, Joel; Andreassen, Ole Andreas & Djurovic, Srdjan (2017). Using Stem Cells to Understand the Underlying Mechanisms of Polygenic Risk of Severe Mental Disorders.
  • Strand, Martin Frank; Krauss, Stefan & Machon, Ondrej (2013). Modulating the Hedgehog pathway.

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