Three Hybrid Technology Hub master students graduated this semester
July 2, 2020 11:32 AM
This semester, three master students involved in HTH and Organ-on-a-chip-projects submitted their master thesis. The students graduated from the Department of Chemistry, UiO and they all recieved the grade A!
New article: Preclinical Lead Optimization of a 1,2,4-Triazole Based Tankyrase Inhibitor
June 25, 2020 3:55 PM
Jo Waaler and Stefan Krauss published an article on the chemical synthesis of a novel tankyrase inhibitor series. Tankyrase1/2 is a central biotarget at the cross road between WNT/YAP and PGC-1a signaling with implications in tissue differentiation and a broad spectrum of diseases.
New article: Dysregulation of BRD4 Function Underlies the Functional Abnormalities of MeCP2 Mutant Neurons
June 18, 2020 1:45 PM
Gareth Sullivan has co-authored a paper on the utilisation of brain organoids to demonstrate that the bromodomain chromatin reader protein BRD4 dysregulations is a critical driver for RETT syndrome (RTT) etiology and suggests that targeting BRD4 could be a potential therapeutic opportunity for RTT.
SARS-CoV-2 and COVID19 research at The Hybrid Technology Hub
May 18, 2020 12:53 PM
Several Groups at the Hybrid Technology Hub are involved in Research on the SARS-CoV-2 coronavirus and the COVID19 diesease. Here we present Simon Rayners project; Integrated novel intervention strategies for COVID-19 : Using data mining to fight current and future pandemics
New article: Inhibition of the prostaglandin D2–GPR44/DP2 axis improves human islet survival and function
May 15, 2020 9:59 AM
Shadab Abadpour and Hanne Scholz have a new article out in Diabetologica on improving human islet survival and function.