Jan Magnus Aronsen

Associate Professor - Experimental Cardiology
Image of Jan Magnus Aronsen
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Visiting address Sognsvannsveien 9 Domus Medica 2 etg. 0372 Oslo
Postal address Postboks 1103 Blindern 0317 Oslo

Academic interests

Experimental cardiology, aiming to develop new treatments for cardiac disease by identification of molecular mechanisms that control ion transporters or gene networks in the heart.

Courses taught

  • Molecular medicine, physiology
  • Cardiovascular pharmacology
  • E-learning development

Background

MD with PhD in experimental cardiology. Research previously performed at Oslo University Hospital and KU Leuven, Belgium.

Positions held

  • Research Council of Norway, Board member
  • Teaching comittee for 2nd year of Medical education ("Modul 2), Chair
  • Past:
Tags: Heart, Electrophysiology, Signaling, Phosphodiesterases, Translational research, Gene programs, Heart failure, Arrhythmias

Publications

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  • Tonne, Hilde; Ruud, Kenneth; Aronsen, Jan Magnus; Aamot, Eli; Melleby, Karianne & Hansen, Mette Halskov [Show all 10 contributors for this article] (2022). Statsråden omtaler situasjonen som «alvorlig». Realiteten er at det er en oppkonstruert krise. Aftenposten.
  • Aronsen, Jan Magnus; De Smedt, Koenraad; Heggland, Ingrid; Dingsør, Liv; Tronstad, Stein & Pedersen, Ole Petter [Show all 8 contributors for this article] (2020). Hvordan få økt deling og gjenbruk av forskningsdata? Khrono.no. ISSN 1894-8995.
  • Rønning, Sissel Beate; Carlson, Cathrine Rein; Aronsen, Jan Magnus; Høst, Vibeke; Pisconti, Addolorate & Lunde, Marianne [Show all 11 contributors for this article] (2019). Extracellular Matrix remodeling and multiple signaling pathways are regulated by syndecan-4 during myogenesis.
  • Aronsen, Jan Magnus & Jensenius, Alexander Refsum (2018). «Røvertidsskriftene» er bare toppen av isfjellet. Aftenposten (morgenutg. : trykt utg.). ISSN 0804-3116.
  • Bratland-Sanda, Solfrid; Blikstad-Balas, Marte; De Moor, Katrien; Eriksen, Marianne Hem; Falkum, Ingrid Lossius & Holmen, Heidi [Show all 7 contributors for this article] (2018). Akademia må satse på undervisningskarrierer. Khrono.no. ISSN 1894-8995.
  • Rønning, Sissel Beate; Carlson, Cathrine Rein; Aronsen, Jan Magnus; Høst, Vibeke; Liland, Kristian Hovde & Stang, Espen [Show all 10 contributors for this article] (2017). Syndecan-4 is a skeletal muscle regenerator and is important for normal skeletal muscle fibre development.
  • Aronsen, Jan Magnus; Jensenius, Alexander Refsum; Emblem, Kyrre Eeg; Storeng, Katerini Tagmatarchi; Enberg, Katja & Knutsen, Carl Henrik [Show all 7 contributors for this article] (2017). Kvalitetsparadokset i den norske forskningspolitikken. Khrono.no. ISSN 1894-8995.
  • Aronsen, Jan Magnus; Lind, Guro Elisabeth; Helland, Ingeborg Palm; Schomacker, Anders & Enberg, Katja (2017). Gode nyheter om unge forskeres karriereveier. Khrono.no. ISSN 1894-8995.
  • Aronsen, Jan Magnus; Lind, Guro Elisabeth; Helland, Ingeborg Palm; Schomacker, Anders; Enberg, Katja & Hølleland, Herdis (2017). Karriereveier for økt forskningskvalitet. Khrono.no. ISSN 1894-8995.
  • Strand, Mari Elen; Aronsen, Jan Magnus; Skrbic, Biljana; Gelazaukaite, Monika; Sjaastad, Ivar & Christensen, Geir Arve [Show all 7 contributors for this article] (2016). The heparanase-syndecan-4 axis in the heart: upregulation in response to immune activation indicates a role in cardiac inflammation.
  • Skogestad, Jonas; Albert, Ingrid; Marshall, Serena; Børstad, Mira Halvorsen; Lothe, Gustav B & Sejersted, Ole M [Show all 8 contributors for this article] (2016). Phosphodiesterase 2 regulates Na+/K+-ATPase activity in adult cardiomyocytes.
  • Ruud, Marianne; Frisk, Michael; Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Zhang, Lili & Norseng, Per Andreas [Show all 10 contributors for this article] (2016). Elevated ventricular wall stress disrupts cardiomyocyte t-tubular structure and Ca2+ homeostasis.
  • Mohammadzadeh, Naiyereh; Engebretsen, Kristin V Thunheim; Lunde, Ida Gjervold; Sjaastad, Ivar; Strand, Mari Elen & Marstein, Henriette [Show all 14 contributors for this article] (2016). Lack of the extracellular matrix proteoglycan lumican leads to cardiac dysfunction in response to pressure overload.
  • Mohammadzadeh, Naiyereh; Engebretsen, Kristin; Lunde, Ida Gjervold; Sjaastad, Ivar; Strand, Mari Elen & Marstein, Henriette [Show all 14 contributors for this article] (2016). Lack of the extracellular matrix proteoglycan lumican leads to ventricular dilatation, attenuated hypertrophy and contractile dysfunction in response to pressure overload.
  • Marshall, Serena; Børstad, Mira Halvorsen; Skogestad, Jonas; Albert, Ingrid; Lothe, Gustav B & Espe, Emil Knut Stenersen [Show all 10 contributors for this article] (2016). SERCA2 activation is beneficial in chronic heart disease.
  • Tazmini, Kiarash; Frisk, Michael; Lipsett, David Bruce; Aronsen, Jan Magnus; Sjaastad, Ivar & Øie, Erik [Show all 7 contributors for this article] (2016). Pro-arrhythmic consequences of hypokalemia in atrial cardiomyocytes.
  • Lipsett, David Bruce; Frisk, Michael; Aronsen, Jan Magnus; Singh, Neha; Sejersted, Ole M & Sjaastad, Ivar [Show all 9 contributors for this article] (2016). BIN1 triggers t-tubule development in cardiomyocytes.
  • Kolstad, Terje R Selnes; Macquaide, Niall; Hake, Johan; Aronsen, Jan Magnus; Frisk, Michael & Sjaastad, Ivar [Show all 8 contributors for this article] (2016). Super-resolution imaging reveals dispersion of ryanodine receptor clusters during heart failure.
  • Aronsen, Jan Magnus; Skogestad, Jonas; Hougen, Karina; Lunde, Marianne; Lothe, Gustav B & Albert, Ingrid [Show all 13 contributors for this article] (2016). Physical coupling of PDE3A regulates SERCA2 activity in cardiomyocytes.
  • Albert, Ingrid; Skogestad, Jonas; Carlson, Cathrine Rein; Lunde, Marianne; Marshall, Serena & Lunde, Per Kristian [Show all 8 contributors for this article] (2016). Development of PDE3A-SERCA2 disruptor agents for SERCA2 activation.
  • Norden, Einar Sjaastad; Bergo, Kaja Knudsen; Zhang, Lili; Aronsen, Jan Magnus; Hasic, Almira & Hussain, I. [Show all 8 contributors for this article] (2016). Anti-hypertrophic effects of LCZ696 in chronic cardiac pressure overload.
  • Ruud, Marianne; Frisk, Michael; Aronsen, Jan Magnus; Dahl, Christen Peder; Jølle, Guro Five & Aakhus, Svend [Show all 15 contributors for this article] (2016). Mechanical load regulates cardiomyocyte t-tubular structure and Ca2+ homeostasis.
  • Lipsett, David Bruce; Frisk, Michael; Aronsen, Jan Magnus; Sejersted, Ole M; Sjaastad, Ivar & Christensen, Geir Arve [Show all 7 contributors for this article] (2016). Sarcolemmal structure and function revert to an immature phenotype in failing cardiomyocytes.
  • Kolstad, Terje R Selnes; Macquaide, Niall; Hake, Johan; Aronsen, Jan Magnus; Frisk, Michael & Sjaastad, Ivar [Show all 8 contributors for this article] (2016). Dispersion of ryanodine receptor clusters disrupts calcium sparks in failing cardiomyocyte.
  • Aronsen, Jan Magnus; Singbrant, Sofie; Christensen, Geir Arve & Iversen, Per Ole (2016). Evidence for splenic stress-induced erythropoiesis in mice with post-infarction heart failure.
  • Strand, Mari Elen; Aronsen, Jan Magnus; Skrbic, Biljana; Gelazauskaite, Monika; Sjaastad, Ivar & Christensen, Geir Arve [Show all 7 contributors for this article] (2016). The heparanase-syndecan-4 axis in the heart: upregulation in response to immune activation indicates a role in cardiac inflammation.
  • Marstein, Henriette; Lunde, Per Kristian; Aronsen, Jan Magnus & Sjaastad, Ivar (2016). Inhibition of Alkbh7 regulates cardiac metabolism.
  • Skårdal, Kristine; Espe, Emil Knut Stenersen; Bendiksen, Bård Andre; Aronsen, Jan Magnus; Zhang, Lili & Sjaastad, Ivar (2016). Parametrizing active and passive diastolic function non-invasively using phase contrast MRI.
  • Røe, Åsmund Treu; Ruud, Marianne; Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Sejersted, Ole M & Sjaastad, Ivar [Show all 7 contributors for this article] (2016). Elevated ventricular wall stress disrupts diastolic Calcium homeostasis of the cardiomyocyte.
  • Rønning, Sissel Beate; Carlson, Cathrine Rein; Høst, Vibeke; Aronsen, Jan Magnus; Liland, Kristian Hovde & Stang, Espen [Show all 9 contributors for this article] (2016). Syndecan-4 is important for normal skeletal muscle fibre development .
  • Meier, Silja; Andressen, Kjetil Wessel; Aronsen, Jan Magnus; Sjaastad, Ivar; Skomedal, Tor & Osnes, Jan-Bjørn [Show all 9 contributors for this article] (2015). Enhancement of cAMP-mediated inotropic responses by CNP is regulated differently by PDE2 in normal and failing hearts. BMC Pharmacology & Toxicology. ISSN 2050-6511. 16, p. A66–A66. doi: 10.1186/2050-6511-16-S1-A66.
  • Sadredini, Mani Nikoo; Danielsen, Tore Kristian; Aronsen, Jan Magnus; Manotheepan, Ravinea; Hougen, Karina & Sjaastad, Ivar [Show all 7 contributors for this article] (2015). Beta-adrenoceptor stimulation reveals Ca2+ overload paradox in left ventricular cardiomyocytes from post-infarction rats with and without heart failure.
  • Frisk, Michael; Aronsen, Jan Magnus; Dahl, Christen Peder; Lunde, Ida Gjervold; Jølle, Guro Five & Almaas, Victor [Show all 13 contributors for this article] (2015). Maintained cardiomyocyte t-tubule structure and function in patients with non-dilated hypertrophy.
  • Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Skårdal, Kristine; Zhang, Lili & Sjaastad, Ivar (2015). Noninvasive detection of congestive heart failure in postinfarction rats.
  • Aronsen, Jan Magnus; Skogestad, Jonas; Hougen, Karina; Lunde, Marianne; Lothe, Gustav B & Albert, Ingrid [Show all 12 contributors for this article] (2015). Physical coupling between SERCA2 and PDE3A regulates SERCA2 activity in cardiomyocytes.
  • Lothe, Gustav B; Marshall, Serena; Albert, Ingrid; Børstad, Mira Halvorsen; Skogestad, Jonas & Hougen, Karina [Show all 9 contributors for this article] (2015). Phosphodiesterase 1 regulates SERCA2 activity in adult cardiomyocytes.
  • Hafver, Tandekile Lubelwana; Hodne, Kjetil; Wanichawan, Pimthanya; Aronsen, Jan Magnus; Dalhus, Bjørn & Lunde, Per Kristian [Show all 12 contributors for this article] (2015). PP1 associated with cardiac NCX1 regulates exchange activity by dephosphorylating pSer-68-PLM.
  • Tazmini, Kiarash; Frisk, Michael; Aronsen, Jan Magnus; Sjaastad, Ivar; Øie, Eric & Louch, William Edward (2015). Pro-arrhythmic consequences of hypokalemia in atrial cardiomyocytes.
  • Kolstad, Terje R Selnes; MacQuaide, Niall; Hake, Johan; Aronsen, Jan Magnus; Frisk, Michael & Sjaastad, Ivar [Show all 8 contributors for this article] (2015). Super-resolution imaging of ryanodine receptor cluster organization in normal and failing rat cardiac myocytes.
  • Kolstad, Terje R Selnes; Macquaide, Niall; Hake, Johan; Aronsen, Jan Magnus; Frisk, Michael & Sjaastad, Ivar [Show all 8 contributors for this article] (2015). Super-resolution imaging of ryanodine receptor cluster organization in normal and failing rat cardiac myocytes.
  • Mohammadzadeh, Naiyereh; Andenæs, Kine; Engebretsen, Kristin V.; Lunde, Ida Gjervold; Sjaastad, Ivar & Marstein, Henriette [Show all 12 contributors for this article] (2015). The role of lumican in Cardiac pressure overload.
  • Børstad, Mira Halvorsen; Albert, Ingrid; Lunde, Marianne; Carlson, Cathrine Rein; Sjaastad, Ivar & Aronsen, Jan Magnus (2015). Molecular mechanisms for PDE3A mediated inhibition of SERCA2 activity.
  • Marshall, Serena; Aronsen, Jan Magnus; Skogestad, Jonas; Albert, Ingrid; Lothe, Gustav B & Lunde, Per Kristian [Show all 13 contributors for this article] (2015). Dual PDE3A coupling to AKAP18 and SERCA2 Controls SERCA2 Activity in adult cardiomyocytes.
  • Lipsett, David Bruce; Frisk, Michael; Aronsen, Jan Magnus; Singh, Neha; Sejersted, Ole M & Sjaastad, Ivar [Show all 9 contributors for this article] (2015). BIN1 regulates t-tubule growth during cardiac development and disease.
  • Lipsett, David Bruce; Frisk, Michael; Aronsen, Jan Magnus; Singh, Neha; Sejersted, Ole M & Sjaastad, Ivar [Show all 9 contributors for this article] (2015). BIN1 regulates t-tubule growth during cardiac development and disease.
  • Lipsett, David Bruce; Frisk, Michael; Aronsen, Jan Magnus; Singh, Neha; Sejersted, Ole M & Sjaastad, Ivar [Show all 9 contributors for this article] (2015). BIN1 regulates t-tubule growth during cardiac development and diseases.
  • Lipsett, David Bruce; Frisk, Michael; Singh, Neha; Aronsen, Jan Magnus; Marszalec, William & Sjaastad, Ivar [Show all 9 contributors for this article] (2015). Bridging integrator 1 (B1N1) initiates t-tubule growth cardiac development and disease.
  • Ruud, Marianne; Frisk, Michael; Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Norseng, Per Andreas & Sjaastad, Ivar [Show all 9 contributors for this article] (2015). Elevated ventricular wall stress disrupts cardiomyocyte t-tubular structure and Ca2+ homeostasis.
  • Ruud, Marianne; Frisk, Michael; Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Norseng, Per Andreas & Sjaastad, Ivar [Show all 9 contributors for this article] (2015). Elevated ventricular wall stress disrupts cardiomyocyte t-tubular structure and Ca2+ homeostasis.
  • Sadredini, Mani Nikoo; Danielsen, Tore Kristian; Aronsen, Jan Magnus; Manotheepan, Ravinea; Hougen, Karina & Sjaastad, Ivar [Show all 7 contributors for this article] (2015). Beta-adrenoreceptor stimulation reveals Ca2+ overload paradox in left ventricular cardiomyocytes from post-infarction rats with and without heart failure.
  • Ruud, Marianne; Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Norseng, Per Andreas; Sjaastad, Ivar & Sejersted, Ole M [Show all 8 contributors for this article] (2015). Elevated ventricular wall stress disrupts cardiomyocyte t-tubular structure and Ca 2+ homeostasis.
  • Albert, Ingrid; Børstad, Mira Halvorsen; Carlson, Cathrine Rein; Calejo, Anna; Skogestad, Jonas & Lunde, Marianne [Show all 10 contributors for this article] (2015). Development of SERCA2 activating agents.
  • Mohammadzadeh, Naiyereh; Andenæs, Kine; Engebretsen, Kristin V Thunheim; Lunde, Ida Gjervold; Sjaastad, Ivar & Marstein, Henriette [Show all 12 contributors for this article] (2015). The role of lumican in Cardiac pressure overload.
  • Ruud, Marianne; Frisk, Michael; Norseng, Per Andreas; Røe, Åsmund Treu; Espe, Emil Knut Stenersen & Aronsen, Jan Magnus [Show all 10 contributors for this article] (2015). Regulation of cardiomyocyte t-tubule organization and density by ventricular wall stress. Biophysical Journal. ISSN 0006-3495. 108, p. 443a–443a.
  • Lipsett, David Bruce; Frisk, Michael; Singh, Neha; Aronsen, Jan Magnus; Marszalec, William & Sejersted, Ole M [Show all 10 contributors for this article] (2015). Bridging integrator 1 (BIN1) initiates t-tubule Growth during Cardiac Development and disease. Biophysical Journal. ISSN 0006-3495. 108, p. 130a–130a.
  • Hafver, Tandekile Lubelwana; Wanichawan, Pimthanya; Hodne, Kjetil; Aronsen, Jan Magnus; Dalhus, Bjørn & Lunde, Marianne [Show all 12 contributors for this article] (2015). Anchoring onto NCX1 facilitates dephosphorylation of P-SER68-PLM. Biophysical Journal. ISSN 0006-3495. 108, p. 584a–584a.
  • Aronsen, Jan Magnus (2018). Molecular mediators of chronic heart disease. Universitetet i Oslo. ISSN 978-82-8377-205-0.

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Published July 1, 2019 6:27 AM - Last modified May 3, 2022 9:25 PM

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