Jan Magnus Aronsen

Associate Professor - Division of Physiology
Image of Jan Magnus Aronsen
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Visiting address Sognsvannsveien 9 Domus Medica 0372 OSLO
Postal address Postboks 1103 Blindern 0317 OSLO

Academic interests

Experimental cardiology, aiming to develop new treatments for cardiac disease by identification of molecular mechanisms that control ion transporters or gene networks in the heart.

Courses taught

  • Molecular medicine, physiology
  • Cardiovascular pharmacology

Background

MD with PhD in experimental cardiology. Research previously performed at Oslo University Hospital and KU Leuven, Belgium.

Positions held

  • The young academy of Norway, vice-chair
  • Research Council of Norway, board member
  • EOSC FAIR working group, member
Tags: Heart, Electrophysiology, Signaling, Phosphodiesterases, Translational research, Gene programs, Heart failure, Arrhythmias

Publications

  • Lipsett, David Bruce; Frisk, Michael; Aronsen, Jan Magnus; Norden, Einar Sjaastad; Buonarati, Olivia R.; Cataliotti, Alessandro; Hell, Johannes W.; Sjaastad, Ivar; Christensen, Geir Arve & Louch, William Edward (2019). Cardiomyocyte substructure reverts to an immature phenotype during heart failure. Journal of Physiology.  ISSN 0022-3751.  597(7), s 1833- 1853 . doi: 10.1113/JP277273
  • Mathiesen, Sabrina Bech; Lunde, Marianne; Aronsen, Jan Magnus; Romaine, Andreas; Kaupang, Anita; Martinsen, Marita; De Souza, Gustavo Antonio; Nyman, Tuula Anneli; Sjaastad, Ivar; Christensen, Geir Arve & Carlson, Cathrine Rein (2019). The cardiac syndecan-4 interactome reveals a role for syndecan-4 in nuclear translocation of muscle LIM protein (MLP). Journal of Biological Chemistry.  ISSN 0021-9258.  294(22), s 8717- 8731 . doi: 10.1074/jbc.RA118.006423
  • Mcginley, Gary George; Bendiksen, Bård Andre; Zhang, Lili; Aronsen, Jan Magnus; Norden, Einar Sjaastad; Sjaastad, Ivar & Espe, Emil Knut Stenersen (2019). Accelerated magnetic resonance imaging tissue phase mapping of the rat myocardium using compressed sensing with iterative soft-thresholding. PLOS ONE.  ISSN 1932-6203.  14:e0218874(7), s 1- 17 . doi: 10.1371/journal.pone.0218874
  • Mohammadzadeh, Naiyereh; Lunde, Ida Gjervold; Andenæs, Kine; Strand, Mari Elen; Aronsen, Jan Magnus; Skrbic, Biljana; Marstein, Henriette; Bandlien, Caroline; Nygård, Ståle; Gorham, Joshua; Sjaastad, Ivar; Chakravarti, Shukti; Christensen, Geir Arve; Engebretsen, Kristin V Thunheim & Tønnessen, Theis (2019). The extracellular matrix proteoglycan lumican improves survival and counteracts cardiac dilatation and failure in mice subjected to pressure overload. Scientific Reports.  ISSN 2045-2322.  9:9206, s 1- 13 . doi: 10.1038/s41598-019-45651-9
  • Røe, Åsmund Treu; Ruud, Marianne; Espe, Emil Knut Stenersen; Manfra, Ornella; Longobardi, S; Aronsen, Jan Magnus; Norden, Einar Sjaastad; Husebye, T.; Kolstad, Terje R Selnes; Cataliotti, Alessandro; Christensen, Geir Arve; Sejersted, Ole M; Niederer, Steven A.; Andersen, Geir Øystein; Sjaastad, Ivar & Louch, William Edward (2019). Regional diastolic dysfunction in post-infarction heart failure: role of local mechanical load and SERCA expression. Cardiovascular Research.  ISSN 0008-6363.  115(4), s 752- 764 . doi: 10.1093/cvr/cvy257
  • Skogestad, Jonas; Aronsen, Jan Magnus; Tovsrud, Nils; Wanichawan, Pimthanya; Hougen, Karina; Stokke, Mathis Korseberg; Carlson, Cathrine Rein; Sjaastad, Ivar; Sejersted, Ole M & Swift, Fredrik (2019). Coupling of the Na+/K+-ATPase to Ankyrin B controls Na+/Ca2+ exchanger activity in cardiomyocytes. Cardiovascular Research.  ISSN 0008-6363. . doi: 10.1093/cvr/cvz087
  • Skogestad, Jonas; Lines, Glenn; Louch, William Edward; Sejersted, Ole M; Sjaastad, Ivar & Aronsen, Jan Magnus (2019). Evidence for heterogeneous subsarcolemmal Na+ Levels in rat ventricular myocytes. American Journal of Physiology. Heart and Circulatory Physiology.  ISSN 0363-6135.  316(5)
  • Sokolova, Marina; Sjaastad, Ivar; Louwe, Maria Cornelia; Alfsnes, Katrine; Aronsen, Jan Magnus; Zhang, Lili; Haugstad, Solveig Bjærum; Bendiksen, Bård Andre; Øgaard, Jonas; Bliksøen, Marte; Lien, Egil; Berge, Rolf Kristian; Aukrust, Pål; Ranheim, Trine & Yndestad, Arne (2019). NLRP3 inflammasome promotes myocardial remodeling during diet-induced obesity. Frontiers in Immunology.  ISSN 1664-3224.  10:1621(JULY), s 1- 13 . doi: 10.3389/fimmu.2019.01621 Full text in Research Archive.
  • Andenæs, Kine; Lunde, Ida Gjervold; Mohammadzadeh, Naiyereh; Dahl, Christen Peder; Aronsen, Jan Magnus; Strand, Mari Elen; Palmero, Sheryl; Sjaastad, Ivar; Christensen, Geir Arve; Engebretsen, Kristin V Thunheim & Tønnessen, Theis (2018). The extracellular matrix proteoglycan fibromodulin is upregulated in clinical and experimental heart failure and affects cardiac remodeling. PLOS ONE.  ISSN 1932-6203.  13(7), s 1- 20 . doi: 10.1371/journal.pone.0201422 Full text in Research Archive.
  • Kolstad, Terje R Selnes; Brink, Jonas van Den; Macquaide, Niall; Lunde, Per Kristian; Frisk, Michael; Aronsen, Jan Magnus; Norden, Einar Sjaastad; Cataliotti, Alessandro; Sjaastad, Ivar; Sejersted, Ole M; Edwards, Andrew; Lines, Glenn Terje & Louch, William Edward (2018). Ryanodine receptor dispersion disrupts Ca2+ release in failing cardiac myocytes. eLIFE.  ISSN 2050-084X.  7 . doi: 10.7554/eLife.39427 Full text in Research Archive.
  • Melleby, Arne Olav; Romaine, Andreas; Aronsen, Jan Magnus; Veras, Ioanni; Zhang, Lili; Sjaastad, Ivar; Lunde, Ida Gjervold & Christensen, Geir Arve (2018). A novel method for high precision aortic constriction that allows for generation of specific cardiac phenotypes in mice. Cardiovascular Research.  ISSN 0008-6363. . doi: 10.1093/cvr/cvy141
  • Skogestad, Jonas & Aronsen, Jan Magnus (2018). Hypokalemia-induced arrhythmias and heart failure: New insights and implications for therapy. Frontiers in Physiology.  ISSN 1664-042X.  9:1500, s 1- 11 . doi: 10.3389/fphys.2018.01500
  • Smyrnias, Ioannis; Goodwin, Normann; Wachten, Dagmar; Skogestad, Jonas; Aronsen, Jan Magnus; Robinson, Emma Louise; Demydenko, Kateryna; Segonds-Pichon, Anne; Oxley, David; Sadayappan, Sakthivel; Sipido, Karin; Bootman, Martin D. & Roderick, Hywel Llewelyn (2018). Contractile responses to endothelin-1 are regulated by PKC phosphorylation of cardiac myosin binding protein-C in rat ventricular myocytes. Journal of Molecular and Cellular Cardiology.  ISSN 0022-2828.  117, s 1- 18 . doi: 10.1016/j.yjmcc.2018.02.012
  • Aronsen, Jan Magnus; Espe, Emil Knut Stenersen; Young-Halvorsen, Kristine Skårdal; Hasic, Almira; Zhang, Lili & Sjaastad, Ivar (2017). Noninvasive stratification of postinfarction rats based on the degree of cardiac dysfunction using magnetic resonance imaging and echocardiography. American Journal of Physiology. Heart and Circulatory Physiology.  ISSN 0363-6135.  312(5), s H932- H942 . doi: 10.1152/ajpheart.00668.2016
  • Dhondup, Yangchen; Sjaastad, Ivar; Sandanger, Øystein; Aronsen, Jan Magnus; Ahmed, Muhammad Shakil; Attramadal, Håvard; Finsen, Alexandra; Zhang, Lili; Ranheim, Trine; Alfsnes, Katrine; Aukrust, Pål; Christensen, Geir Arve; Yndestad, Arne & Vinge, Leif Erik (2017). Toll-like receptor 9 promotes survival in SERCA2a KO heart failure mice. Mediators of Inflammation.  ISSN 0962-9351.  2017:9450439, s 1- 11 . doi: 10.1155/2017/9450439 Full text in Research Archive.
  • Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Eriksen, Morten; Sejersted, Ole M; Zhang, Lili & Sjaastad, Ivar (2017). Regional dysfunction after myocardial infarction in rats. Circulation Cardiovascular Imaging.  ISSN 1941-9651.  10(9), s e005997 . doi: 10.1161/CIRCIMAGING.116.005997
  • Espe, Emil Knut Stenersen; Young-Halvorsen, Kristine Skårdal; Aronsen, Jan Magnus; Zhang, Lili & Sjaastad, Ivar (2017). A semiautomatic method for rapid segmentation of velocity-encoded myocardial magnetic resonance imaging data. Magnetic Resonance in Medicine.  ISSN 0740-3194.  78(3), s 1199- 1207 . doi: 10.1002/mrm.26486
  • Gattoni, Sara; Røe, Åsmund Treu; Aronsen, Jan Magnus; Sjaastad, Ivar; Louch, William Edward; Smith, Nicolas P. & Niederer, Steven A. (2017). Compensatory and decompensatory alterations in cardiomyocyte Ca2+ dynamics in hearts with diastolic dysfunction following aortic banding. Journal of Physiology.  ISSN 0022-3751.  595(12), s 3867- 3889 . doi: 10.1113/JP273879
  • Landfors, Miriam; Johansen, Jostein; Aronsen, Jan Magnus; Vågbø, Cathrine Broberg; Doré, Louis C.; He, Chuan; Sjaastad, Ivar; Sætrom, Pål; Fedorcsák, Péter; Dahl, John Arne; Aanes, Håvard; Fusser, Markus & Klungland, Arne (2017). Genome-wide profiling of DNA 5-hydroxymethylcytosine during rat Sertoli cell maturation. Cell Discovery.  ISSN 2056-5968.  3 . doi: 10.1038/celldisc.2017.13 Full text in Research Archive.
  • Meier, Silja; Andressen, Kjetil Wessel; Aronsen, Jan Magnus; Sjaastad, Ivar; Hougen, Karina; Skomedal, Tor; Osnes, Jan-Bjørn; Qvigstad, Eirik; Levy, Finn Olav & Moltzau, Lise Roman (2017). PDE3 inhibition by C-type natriuretic peptide-induced cGMP enhances cAMP-mediated signaling in both non-failing and failing hearts. European Journal of Pharmacology.  ISSN 0014-2999.  812, s 174- 183 . doi: 10.1016/j.ejphar.2017.07.014
  • Romaine, Andreas; Sørensen, Ida Wiig; Zeltz, Cedric; Lu, Ning; Erusappan, Pugazendhi Murugan; Melleby, Arne Olav; Zhang, Lili; Bendiksen, Bård Andre; Robinson, EL; Aronsen, Jan Magnus; Herum, Kate Louise Møller; Danielsen, Håvard Emil; Sjaastad, Ivar; Christensen, Geir Arve & Gullberg, Donald (2017). Overexpression of integrin α11 induces cardiac fibrosis in mice. Acta Physiologica Scandinavica.  ISSN 0001-6772.  222:e13025(2), s 1- 17 . doi: 10.1111/apha.12932
  • Røe, Åsmund Treu; Aronsen, Jan Magnus; Young-Halvorsen, Kristine Skårdal; Hamdani, Nazha; Linke, Wolfgang A.; Danielsen, Håvard Emil; Sejersted, Ole M; Sjaastad, Ivar & Louch, William Edward (2017). Increased passive stiffness promotes diastolic dysfunction despite improved Ca2+ handling during left ventricular concentric hypertrophy. Cardiovascular Research.  ISSN 0008-6363.  113(10), s 1161- 1172 . doi: 10.1093/cvr/cvx087
  • Thienpont, Bernard; Aronsen, Jan Magnus; Robinson, Emma Louise; Okkenhaug, Hanneke; Loche, Elena; Ferrini, Arianna; Brien, Patrick; Alkass, Kanar; Tomasso, Antonio; Agrawal, Asmita; Bergmann, Olaf; Sjaastad, Ivar; Wolf, Reik & Roderick, Hywel Llewelyn (2017). The H3K9 dimethyltransferases EHMT1/2 protect against pathological cardiac hypertrophy. Journal of Clinical Investigation.  ISSN 0021-9738.  127(1), s 335- 348 . doi: 10.1172/JCI88353
  • Aronsen, Jan Magnus; Louch, William Edward & Sjaastad, Ivar (2016). Cardiomyocyte Ca2+ dynamics: Clinical perspectives. Scandinavian Cardiovascular Journal.  ISSN 1401-7431.  50(2), s 65- 77 . doi: 10.3109/14017431.2015.1136079
  • Frisk, Michael; Ruud, Marianne; Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Røe, Åsmund Treu; Zhang, Lili; Norseng, Per Andreas; Sejersted, Ole M; Christensen, Geir Arve; Sjaastad, Ivar & Louch, William Edward (2016). Elevated ventricular wall stress disrupts cardiomyocyte t-tubule structure and calcium homeostasis. Cardiovascular Research.  ISSN 0008-6363. . doi: 10.1093/cw111
  • Hafver, Tandekile Lubelwana; Hodne, Kjetil; Wanichawan, Pimthanya; Aronsen, Jan Magnus; Dalhus, Bjørn; Lunde, Per Kristian; Lunde, Marianne; Martinsen, Marita; Enger, Ulla Helene; Fuller, William; Sjaastad, Ivar; Louch, William Edward; Sejersted, Ole M & Carlson, Cathrine Rein (2016). Protein phosphatase 1c associated with the cardiac sodium calcium exchanger 1 regulates its activity by dephosphorylating Serine 68-phosphorylated phospholemman. Journal of Biological Chemistry.  ISSN 0021-9258.  291(9), s 4561- 4579 . doi: 10.1074/jbc.M115.677898 Show summary
  • Hortemo, Kristin Halvorsen; Lunde, Per Kristian; Anonsen, Jan Haug; Kvaløy, Heidi; Munkvik, Morten; Rehn, Tommy Aune; Sjaastad, Ivar; Lunde, Ida Gjervold; Aronsen, Jan Magnus & Sejersted, Ole M (2016). Exercise training increases protein O-GlcNAcylation in rat skeletal muscle. Physiological Reports.  ISSN 2051-817X.  4(18), s e12896 . doi: 10.14814/phy2.12896 Full text in Research Archive.
  • Sadredini, Mani; Danielsen, Tore Kristian; Aronsen, Jan Magnus; Manotheepan, Ravinea; Hougen, Karina; Sjaastad, Ivar & Stokke, Mathis Korseberg (2016). Beta-adrenoceptor stimulation reveals Ca2+ waves and sarcoplasmic reticulum Ca2+ depletion in left ventricular cardiomyocytes from post-infarction rats with and without heart failure. PLOS ONE.  ISSN 1932-6203.  11(4) . doi: 10.1371/journal.pone.0153887
  • Young-Halvorsen, Kristine Skårdal; Espe, Emil Knut Stenersen; Zhang, Lili; Aronsen, Jan Magnus & Sjaastad, Ivar (2016). Three-directional evaluation of mitral flow in the rat heart by phase-contrast cardiovascular magnetic resonance. PLOS ONE.  ISSN 1932-6203.  11(3) . doi: 10.1371/journal.pone.0150536 Full text in Research Archive.
  • Aronsen, Jan Magnus; Skogestad, Jonas; Lewalle, Alexandre; Louch, William Edward; Hougen, Karina; Stokke, Mathis Korseberg; Swift, Fredrik; Niederer, Steven; Smith, Nic P.; Sejersted, Ole M & Sjaastad, Ivar (2015). Hypokalaemia induces Ca2+ overload and Ca2+ waves in ventricular myocytes by reducing Na+ ,K+-ATPase α2 activity. Journal of Physiology.  ISSN 0022-3751.  593(6), s 1509- 1521 . doi: 10.1113/jphysiol.2014.279893
  • Dhondup, Yangchen; Sjaastad, Ivar; Scott, Helge; Sandanger, Øystein; Zhang, Lili; Haugstad, Solveig Bjærum; Aronsen, Jan Magnus; Ranheim, Trine; Holmen, Sigve; Alfsnes, Katrine; Ahmed, Muhammad Shakil; Attramadal, Håvard; Gullestad, Lars; Aukrust, Pål; Christensen, Geir Arve; Yndestad, Arne & Vinge, Leif Erik (2015). Sustained toll-like receptor 9 activation promotes systemic and cardiac inflammation, and aggravates diastolic heart failure in SERCA2a KO Mice. PLOS ONE.  ISSN 1932-6203.  10:e0139715(10) . doi: 10.1371/journal.pone.0139715 Full text in Research Archive.
  • Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Eriksen, Guro Søe; Zhang, Lili; Smiseth, Otto A.; Edvardsen, Thor; Sjaastad, Ivar & Eriksen, Morten (2015). Assessment of regional myocardial work in rats. Circulation Cardiovascular Imaging.  ISSN 1941-9651.  8 . doi: 10.1161/CIRCIMAGING.114.002695
  • Hortemo, Kristin Halvorsen; Aronsen, Jan Magnus; Lunde, Ida Gjervold; Sjaastad, Ivar; Lunde, Per Kristian & Sejersted, Ole M (2015). Exhausting treadmill running causes dephosphorylation of sMLC2 and reduced level of myofilament MLCK2 in slow twitch rat soleus muscle. Physiological Reports.  ISSN 2051-817X.  3(2) . doi: 10.14814/phy2.12285 Full text in Research Archive.
  • Lauritzen, Knut Husø; Kleppa, Liv; Aronsen, Jan Magnus; Eide, Lars; Carlsen, Harald; Haugen, Øyvind Pernell; Sjaastad, Ivar; Klungland, Arne; Rasmussen, Lene Juel; Attramadal, Håvard; Storm-Mathisen, Jon & Bergersen, Linda Hildegard (2015). Impaired dynamics and function of mitochondria caused by mtDNA toxicity leads to heart failure. American Journal of Physiology. Heart and Circulatory Physiology.  ISSN 0363-6135.  309(3), s H434- H449 . doi: 10.1152/ajpheart.00253.2014
  • Ottesen, Anett Hellebø; Louch, William Edward; Carlson, Cathrine Rein; Landsverk, Ole J. B.; Kurola, Jouni; Johansen, Rune Forstrøm; Moe, Morten Kaare; Aronsen, Jan Magnus; Høiseth, Arne Didrik; Jarstadmarken, Hilde; Nygård, Ståle; Bjørås, Magnar; Sjaastad, Ivar; Pettilä, Ville; Stridsberg, Mats; Omland, Torbjørn; Christensen, Geir Arve & Røsjø, Helge (2015). Secretoneurin is a novel prognostic cardiovascular biomarker associated with cardiomyocyte calcium handling. Journal of the American College of Cardiology.  ISSN 0735-1097.  65(4), s 339- 351 . doi: 10.1016/j.jacc.2014.10.065
  • Strand, Mari Elen; Aronsen, Jan Magnus; Braathen, Bjørn; Sjaastad, Ivar; Kvaløy, Heidi; Tønnessen, Theis; Christensen, Geir Arve & Lunde, Ida Gjervold (2015). Shedding of syndecan-4 promotes immune cell recruitment and mitigates cardiac dysfunction after lipopolysaccharide challenge in mice. Journal of Molecular and Cellular Cardiology.  ISSN 0022-2828.  88, s 133- 144 . doi: 10.1016/j.yjmcc.2015.10.003
  • Zoccarato, Anna; Surdo, Nicoletta C.; Aronsen, Jan Magnus; Fields, Laura A.; Mancuso, Luisa; Dodoni, Giuliano; Stangherlin, Alessandra; Livie, Craig; Jiang, He; Sin, Yuan Yan; Gesellchen, Frank; Terrin, Anna; Baillie, George S.; Nicklin, Stuart A; Graham, Delyth; Szabo-Fresnais, Nicolas; Krall, Judith; Vandeput, Fabrice; Movsesian, Matthew A.; Furlan, Leonardo; Corsetti, Veronica; Hamilton, Graham; Lefkimmiatis, Konstantinos; Sjaastad, Ivar & Zaccolo, Manuela (2015). Cardiac hypertrophy is inhibited by a local pool of cAMP regulated by phosphodiesterase 2. Circulation Research.  ISSN 0009-7330.  117(8), s 707- 719 . doi: 10.1161/CIRCRESAHA.114.305892
  • Boardman, Neoma Tove; Aronsen, Jan Magnus; Louch, William Edward; Sjaastad, Ivar; Willoch, Frode; Christensen, Geir Arve; Sejersted, Ole M & Aasum, Ellen (2014). Impaired left ventricular mechanical and energetic function in mice after cardiomyocyte-specific excision of Serca2. American Journal of Physiology. Heart and Circulatory Physiology.  ISSN 0363-6135. . doi: 10.1152/ajpheart.00741.2013 Full text in Research Archive.
  • Boardman, Neoma Tove; Aronsen, Jan Magnus; Louch, William Edward; Sjaastad, Ivar; Willoch, Frode; Christensen, Geir Arve; Sejersted, Ole M & Aasum, Ellen (2014). Impaired left ventricular mechanical and energetic function in mice after cardiomyocyte-specific excision of Serca2. American Journal of Physiology. Heart and Circulatory Physiology.  ISSN 0363-6135.  306(7), s H1018- H1024 . doi: 10.1152/ajpheart.00741.2013

View all works in Cristin

  • Rønning, Sissel Beate; Carlson, Cathrine Rein; Aronsen, Jan Magnus; Høst, Vibeke; Pisconti, Addolorate; Lunde, Marianne; Liland, Kristian Hovde; Sjaastad, Ivar; Kolset, Svein Olav; Christensen, Geir Arve & Pedersen, Mona Elisabeth (2019). Extracellular Matrix remodeling and multiple signaling pathways are regulated by syndecan-4 during myogenesis.
  • Aronsen, Jan Magnus (2018). Molecular mediators of chronic heart disease.
  • Aronsen, Jan Magnus & Jensenius, Alexander Refsum (2018). «Røvertidsskriftene» er bare toppen av isfjellet. Aftenposten. Show summary
  • Bratland-Sanda, Solfrid; Blikstad-Balas, Marte; De Moor, Katrien; Eriksen, Marianne Hem; Falkum, Ingrid Lossius; Holmen, Heidi & Aronsen, Jan Magnus (2018). Akademia må satse på undervisningskarrierer. Khrono.no.  ISSN 1894-8995.
  • Aronsen, Jan Magnus; Jensenius, Alexander Refsum; Emblem, Kyrre Eeg; Storeng, Katerini Tagmatarchi; Enberg, Katja; Knutsen, Carl Henrik & Lind, Guro Elisabeth (2017). Kvalitetsparadokset i den norske forskningspolitikken. Khrono.no.  ISSN 1894-8995. Show summary
  • Aronsen, Jan Magnus; Lind, Guro Elisabeth; Helland, Ingeborg Palm; Schomacker, Anders & Enberg, Katja (2017). Gode nyheter om unge forskeres karriereveier. Khrono.no.  ISSN 1894-8995.
  • Aronsen, Jan Magnus; Lind, Guro Elisabeth; Helland, Ingeborg Palm; Schomacker, Anders; Enberg, Katja & Hølleland, Herdis (2017). Karriereveier for økt forskningskvalitet. Khrono.no.  ISSN 1894-8995.
  • Rønning, Sissel Beate; Carlson, Cathrine Rein; Aronsen, Jan Magnus; Høst, Vibeke; Liland, Kristian Hovde; Stang, Espen; Sjaastad, Ivar; Kolset, Svein Olav; Christensen, Geir Arve & Pedersen, Mona Elisabeth (2017). Syndecan-4 is a skeletal muscle regenerator and is important for normal skeletal muscle fibre development..
  • Albert, Ingrid; Skogestad, Jonas; Carlson, Cathrine Rein; Lunde, Marianne; Marshall, Serena; Lunde, Per Kristian; Sjaastad, Ivar & Aronsen, Jan Magnus (2016). Development of PDE3A-SERCA2 disruptor agents for SERCA2 activation..
  • Aronsen, Jan Magnus; Singbrant, Sofie; Christensen, Geir Arve & Iversen, Per Ole (2016). Evidence for splenic stress-induced erythropoiesis in mice with post-infarction heart failure.
  • Aronsen, Jan Magnus; Skogestad, Jonas; Hougen, Karina; Lunde, Marianne; Lothe, Gustav B; Albert, Ingrid; Marshall, Serena; Børstad, Mira Halvorsen; Lunde, Per Kristian; Morth, Jens Preben; Tasken, Kjetil; Carlson, Cathrine Rein & Sjaastad, Ivar (2016). Physical coupling of PDE3A regulates SERCA2 activity in cardiomyocytes.
  • Kolstad, Terje R Selnes; Macquaide, Niall; Hake, Johan; Aronsen, Jan Magnus; Frisk, Michael; Sjaastad, Ivar; Sejersted, Ole M & Louch, William Edward (2016). Dispersion of ryanodine receptor clusters disrupts calcium sparks in failing cardiomyocyte.
  • Kolstad, Terje R Selnes; Macquaide, Niall; Hake, Johan; Aronsen, Jan Magnus; Frisk, Michael; Sjaastad, Ivar; Sejersted, Ole M & Louch, William Edward (2016). Super-resolution imaging reveals dispersion of ryanodine receptor clusters during heart failure.
  • Lipsett, David Bruce; Frisk, Michael; Aronsen, Jan Magnus; Sejersted, Ole M; Sjaastad, Ivar; Christensen, Geir Arve & Louch, William Edward (2016). Sarcolemmal structure and function revert to an immature phenotype in failing cardiomyocytes.
  • Lipsett, David Bruce; Frisk, Michael; Aronsen, Jan Magnus; Singh, Neha; Sejersted, Ole M; Sjaastad, Ivar; Wasserstrom, J. Andrew; Christensen, Geir Arve & Louch, William Edward (2016). BIN1 triggers t-tubule development in cardiomyocytes.
  • Marshall, Serena; Børstad, Mira Halvorsen; Skogestad, Jonas; Albert, Ingrid; Lothe, Gustav B; Espe, Emil Knut Stenersen; Zhang, Lili; Louch, William Edward; Sjaastad, Ivar & Aronsen, Jan Magnus (2016). SERCA2 activation is beneficial in chronic heart disease.
  • Marstein, Henriette; Lunde, Per Kristian; Aronsen, Jan Magnus & Sjaastad, Ivar (2016). Inhibition of Alkbh7 regulates cardiac metabolism.
  • Mohammadzadeh, Naiyereh; Engebretsen, Kristin V Thunheim; Lunde, Ida Gjervold; Sjaastad, Ivar; Strand, Mari Elen; Marstein, Henriette; Aronsen, Jan Magnus; Nygård, Ståle; Skrbic, Biljana; Bandlien, Caroline; Andenæs, Kine; Chakravarti, Shukti; Christensen, Geir Arve & Tønnessen, Theis (2016). Lack of the extracellular matrix proteoglycan lumican leads to cardiac dysfunction in response to pressure overload.
  • Mohammadzadeh, Naiyereh; Engebretsen, Kristin; Lunde, Ida Gjervold; Sjaastad, Ivar; Strand, Mari Elen; Marstein, Henriette; Aronsen, Jan Magnus; Nygård, Ståle; Skrbic, Biljana; Bandlien, Caroline; Andenæs, Kine; Chakravarti, Shukti; Christensen, Geir Arve & Tønnessen, Theis (2016). Lack of the extracellular matrix proteoglycan lumican leads to ventricular dilatation, attenuated hypertrophy and contractile dysfunction in response to pressure overload.
  • Norden, Einar Sjaastad; Bergo, Kaja Knudsen; Zhang, Lili; Aronsen, Jan Magnus; Hasic, Almira; Hussain, I.; Sjaastad, Ivar & Cataliotti, Alessandro (2016). Anti-hypertrophic effects of LCZ696 in chronic cardiac pressure overload.
  • Ruud, Marianne; Frisk, Michael; Aronsen, Jan Magnus; Dahl, Christen Peder; Jølle, Guro Five; Aakhus, Svend; Lunde, Ida Gjervold; Almaas, Vibeke; Gullestad, Lars; Sjaastad, Ivar; Tønnessen, Theis; Sejersted, Ole M; Norseng, Per Andreas; Christensen, Geir Arve & Louch, William Edward (2016). Mechanical load regulates cardiomyocyte t-tubular structure and Ca2+ homeostasis.
  • Ruud, Marianne; Frisk, Michael; Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Zhang, Lili; Norseng, Per Andreas; Sjaastad, Ivar; Sejersted, Ole M; Christensen, Geir Arve & Louch, William Edward (2016). Elevated ventricular wall stress disrupts cardiomyocyte t-tubular structure and Ca2+ homeostasis.
  • Røe, Åsmund Treu; Ruud, Marianne; Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Sejersted, Ole M; Sjaastad, Ivar & Louch, William Edward (2016). Elevated ventricular wall stress disrupts diastolic Calcium homeostasis of the cardiomyocyte.
  • Rønning, Sissel Beate; Carlson, Cathrine Rein; Høst, Vibeke; Aronsen, Jan Magnus; Liland, Kristian Hovde; Stang, Espen; Kolset, Svein Olav; Christensen, Geir Arve & Pedersen, Mona Elisabeth (2016). Syndecan-4 is important for normal skeletal muscle fibre development.
  • Skogestad, Jonas; Albert, Ingrid; Marshall, Serena; Børstad, Mira Halvorsen; Lothe, Gustav B; Sejersted, Ole M; Sjaastad, Ivar & Aronsen, Jan Magnus (2016). Phosphodiesterase 2 regulates Na+/K+-ATPase activity in adult cardiomyocytes.
  • Skårdal, Kristine; Espe, Emil Knut Stenersen; Bendiksen, Bård Andre; Aronsen, Jan Magnus; Zhang, Lili & Sjaastad, Ivar (2016). Parametrizing active and passive diastolic function non-invasively using phase contrast MRI.
  • Strand, Mari Elen; Aronsen, Jan Magnus; Skrbic, Biljana; Gelazaukaite, Monika; Sjaastad, Ivar; Christensen, Geir Arve & Lunde, Ida Gjervold (2016). The heparanase-syndecan-4 axis in the heart: upregulation in response to immune activation indicates a role in cardiac inflammation.
  • Strand, Mari Elen; Aronsen, Jan Magnus; Skrbic, Biljana; Gelazauskaite, Monika; Sjaastad, Ivar; Christensen, Geir Arve & Lunde, Ida Gjervold (2016). The heparanase-syndecan-4 axis in the heart: upregulation in response to immune activation indicates a role in cardiac inflammation.
  • Tazmini, Kiarash; Frisk, Michael; Lipsett, David Bruce; Aronsen, Jan Magnus; Sjaastad, Ivar; Øie, Erik & Louch, William Edward (2016). Pro-arrhythmic consequences of hypokalemia in atrial cardiomyocytes.
  • Albert, Ingrid; Børstad, Mira Halvorsen; Carlson, Cathrine Rein; Calejo, Anna; Skogestad, Jonas; Lunde, Marianne; Lunde, Per Kristian; Tasken, Kjetil; Sjaastad, Ivar & Aronsen, Jan Magnus (2015). Development of SERCA2 activating agents.
  • Aronsen, Jan Magnus; Skogestad, Jonas; Hougen, Karina; Lunde, Marianne; Lothe, Gustav B; Albert, Ingrid; Marshall, Serena; Lunde, Per Kristian; Morth, Jens Preben; Tasken, Kjetil; Carlson, Cathrine Rein & Sjaastad, Ivar (2015). Physical coupling between SERCA2 and PDE3A regulates SERCA2 activity in cardiomyocytes.
  • Børstad, Mira Halvorsen; Albert, Ingrid; Lunde, Marianne; Carlson, Cathrine Rein; Sjaastad, Ivar & Aronsen, Jan Magnus (2015). Molecular mechanisms for PDE3A mediated inhibition of SERCA2 activity.
  • Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Skårdal, Kristine; Zhang, Lili & Sjaastad, Ivar (2015). Noninvasive detection of congestive heart failure in postinfarction rats.
  • Frisk, Michael; Aronsen, Jan Magnus; Dahl, Christen Peder; Lunde, Ida Gjervold; Jølle, Guro Five; Almaas, Victor; Gullestad, Lars; Christensen, Geir Arve; Aakhus, Svend; Sejersted, Ole M; Tønnessen, Theis; Sjaastad, Ivar & Louch, William Edward (2015). Maintained cardiomyocyte t-tubule structure and function in patients with non-dilated hypertrophy.
  • Frisk, Michael; Ruud, Marianne; Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Røe, Åsmund Treu; Zhang, Lili; Norseng, Per Andreas; Christensen, Geir Arve; Sejersted, Ole M; Sjaastad, Ivar & Louch, William Edward (2015). Ventricular wall stress predicts disruption of cardiomyocyte t-tubule structure and Ca2+ homeostasis across the infarcted heart. Biophysical Journal.  ISSN 0006-3495.  108, s 106a
  • Hafver, Tandekile Lubelwana; Hodne, Kjetil; Wanichawan, Pimthanya; Aronsen, Jan Magnus; Dalhus, Bjørn; Lunde, Per Kristian; Martinsen, Marita; Enger, Ulla Helene; Fuller, William; Louch, William Edward; Sejersted, Ole M & Carlson, Cathrine Rein (2015). PP1 associated with cardiac NCX1 regulates exchange activity by dephosphorylating pSer-68-PLM.
  • Hafver, Tandekile Lubelwana; Wanichawan, Pimthanya; Hodne, Kjetil; Aronsen, Jan Magnus; Dalhus, Bjørn; Lunde, Marianne; Enger, Ulla Helene; Mathisen, Marita; Fuller, William; Sjaastad, Ivar; Sejersted, Ole M & Carlson, Cathrine Rein (2015). Anchoring onto NCX1 facilitates dephosphorylation of P-SER68-PLM. Biophysical Journal.  ISSN 0006-3495.  108, s 584a- 584a
  • Kolstad, Terje R Selnes; MacQuaide, Niall; Hake, Johan; Aronsen, Jan Magnus; Frisk, Michael; Sjaastad, Ivar; Sejersted, Ole M & Louch, William Edward (2015). Super-resolution imaging of ryanodine receptor cluster organization in normal and failing rat cardiac myocytes.
  • Kolstad, Terje R Selnes; Macquaide, Niall; Hake, Johan; Aronsen, Jan Magnus; Frisk, Michael; Sjaastad, Ivar; Sejersted, Ole M & Louch, William Edward (2015). Super-resolution imaging of ryanodine receptor cluster organization in normal and failing rat cardiac myocytes.
  • Lipsett, David Bruce; Frisk, Michael; Aronsen, Jan Magnus; Singh, Neha; Sejersted, Ole M; Sjaastad, Ivar; Wasserstrom, John Andrew; Christensen, Geir Arve & Louch, William Edward (2015). BIN1 regulates t-tubule growth during cardiac development and disease.
  • Lipsett, David Bruce; Frisk, Michael; Aronsen, Jan Magnus; Singh, Neha; Sejersted, Ole M; Sjaastad, Ivar; Wasserstrom, John Andrew; Christensen, Geir Arve & Louch, William Edward (2015). BIN1 regulates t-tubule growth during cardiac development and disease.
  • Lipsett, David Bruce; Frisk, Michael; Aronsen, Jan Magnus; Singh, Neha; Sejersted, Ole M; Sjaastad, Ivar; Wasserstrom, John Andrew; Christensen, Geir Arve & Louch, William Edward (2015). BIN1 regulates t-tubule growth during cardiac development and diseases.
  • Lipsett, David Bruce; Frisk, Michael; Singh, Neha; Aronsen, Jan Magnus; Marszalec, William; Sejersted, Ole M; Sjaastad, Ivar; Wasserstrom, J. Andrew; Christensen, Geir Arve & Louch, William Edward (2015). Bridging integrator 1 (BIN1) initiates t-tubule Growth during Cardiac Development and disease. Biophysical Journal.  ISSN 0006-3495.  108, s 130a- 130a
  • Lipsett, David Bruce; Frisk, Michael; Singh, Neha; Aronsen, Jan Magnus; Marszalec, William; Sjaastad, Ivar; Wasserstrom, Andrew; Christensen, Geir Arve & Louch, William Edward (2015). Bridging integrator 1 (B1N1) initiates t-tubule growth cardiac development and disease.
  • Lothe, Gustav B; Marshall, Serena; Albert, Ingrid; Børstad, Mira Halvorsen; Skogestad, Jonas; Hougen, Karina; Lunde, Per Kristian; Sjaastad, Ivar & Aronsen, Jan Magnus (2015). Phosphodiesterase 1 regulates SERCA2 activity in adult cardiomyocytes.
  • Marshall, Serena; Aronsen, Jan Magnus; Skogestad, Jonas; Albert, Ingrid; Lothe, Gustav B; Lunde, Per Kristian; Monteresi, Stefania; Moltzau, Lise Roman; Qvigstad, Eirik; Skomedal, Tor; Zaccolo, Manuela; Carlson, Cathrine Rein & Sjaastad, Ivar (2015). Dual PDE3A coupling to AKAP18 and SERCA2 Controls SERCA2 Activity in adult cardiomyocytes.
  • Meier, Silja; Andressen, Kjetil Wessel; Aronsen, Jan Magnus; Sjaastad, Ivar; Skomedal, Tor; Osnes, Jan-Bjørn; Qvigstad, Eirik; Levy, Finn Olav & Moltzau, Lise Roman (2015). Enhancement of cAMP-mediated inotropic responses by CNP is regulated differently by PDE2 in normal and failing hearts. BMC Pharmacology & Toxicology.  ISSN 2050-6511.  16, s A66- A66 . doi: 10.1186/2050-6511-16-S1-A66
  • Mohammadzadeh, Naiyereh; Andenæs, Kine; Engebretsen, Kristin V Thunheim; Lunde, Ida Gjervold; Sjaastad, Ivar; Marstein, Henriette; Aronsen, Jan Magnus; Skrbic, Biljana; Bandlien, Caroline; Chakravarti, Shukti; Christensen, Geir Arve & Tønnessen, Theis (2015). The role of lumican in Cardiac pressure overload.
  • Mohammadzadeh, Naiyereh; Andenæs, Kine; Engebretsen, Kristin V.; Lunde, Ida Gjervold; Sjaastad, Ivar; Marstein, Henriette; Aronsen, Jan Magnus; Skrbic, Biljana; Bandlien, Caroline; Chakravarti, Shukti; Christensen, Geir Arve & Tønnessen, Theis (2015). The role of lumican in Cardiac pressure overload.
  • Ruud, Marianne; Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Norseng, Per Andreas; Sjaastad, Ivar; Sejersted, Ole M; Christensen, Geir Arve & Louch, William Edward (2015). Elevated ventricular wall stress disrupts cardiomyocyte t-tubular structure and Ca 2+ homeostasis.
  • Ruud, Marianne; Frisk, Michael; Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Norseng, Per Andreas; Sjaastad, Ivar; Sejersted, Ole M; Christensen, Geir Arve & Louch, William Edward (2015). Elevated ventricular wall stress disrupts cardiomyocyte t-tubular structure and Ca2+ homeostasis.
  • Ruud, Marianne; Frisk, Michael; Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Norseng, Per Andreas; Sjaastad, Ivar; Sejersted, Ole M; Christensen, Geir Arve & Louch, William Edward (2015). Elevated ventricular wall stress disrupts cardiomyocyte t-tubular structure and Ca2+ homeostasis.
  • Ruud, Marianne; Frisk, Michael; Norseng, Per Andreas; Røe, Åsmund Treu; Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Sjaastad, Ivar; Sejersted, Ole M; Christensen, Geir Arve & Louch, William Edward (2015). Regulation of cardiomyocyte t-tubule organization and density by ventricular wall stress. Biophysical Journal.  ISSN 0006-3495.  108, s 443a- 443a
  • Sadredini, Mani Nikoo; Danielsen, Tore Kristian; Aronsen, Jan Magnus; Manotheepan, Ravinea; Hougen, Karina; Sjaastad, Ivar & Stokke, Mathis Korseberg (2015). Beta-adrenoceptor stimulation reveals Ca2+ overload paradox in left ventricular cardiomyocytes from post-infarction rats with and without heart failure.
  • Sadredini, Mani Nikoo; Danielsen, Tore Kristian; Aronsen, Jan Magnus; Manotheepan, Ravinea; Hougen, Karina; Sjaastad, Ivar & Stokke, Mathis Korseberg (2015). Beta-adrenoreceptor stimulation reveals Ca2+ overload paradox in left ventricular cardiomyocytes from post-infarction rats with and without heart failure.
  • Tazmini, Kiarash; Frisk, Michael; Aronsen, Jan Magnus; Sjaastad, Ivar; Øie, Eric & Louch, William Edward (2015). Pro-arrhythmic consequences of hypokalemia in atrial cardiomyocytes.
  • Aronsen, Jan Magnus; Skogestad, Jonas; Hougen, Karina; Lunde, Marianne; Lothe, Gustav B; Lunde, Per Kristian; Morth, Jens Preben; Tasken, Kjetil; Carlson, Cathrine Rein & Sjaastad, Ivar (2014). Hypokalemia induce CA2+ waves by lowering NKA alpha 2 activity in rat ventricular cardiomyocytes.
  • Aronsen, Jan Magnus; Skogestad, Jonas; Hougen, Karina; Lunde, Marianne; Lothe, Gustav B; Lunde, Per Kristian; Morth, Jens Preben; Tasken, Kjetil; Carlson, Cathrine Rein & Sjaastad, Ivar (2014). Physical coupling of PDE3A to SERCA2 regulates SERCA2 activity in cardiomyoyctes.
  • Danielsen, Tore Kristian; Manotheepan, Ravinea; Sadredini, Mani Nikoo; Aronsen, Jan Magnus; Hougen, Karina; Sejersted, Ole M; Sjaastad, Ivar & Stokke, Mathis Korseberg (2014). The effect of exercise training on Ca2+ wave probability after myocardial infarction varies with cardiac function at onset of training.
  • Dugstad, K.; Ulsund, Andrea Hembre; Aronsen, Jan Magnus; Sjaastad, Ivar; Zaccolo, Manuela; Levy, Finn Olav & Andressen, Kjetil Wessel (2014). Unraveling tight spatial regulation of 5-HT4 receptor-mediated inotropic effects using targeted FRET-based cAMP sensors.
  • Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Eriksen, Guro Søe; Zhang, Lili; Smiseth, Otto A.; Edvardsen, Thor; Sjaastad, Ivar & Eriksen, Morten (2014). Assessment of regional myocardial work in rats.

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Published July 1, 2019 6:27 AM - Last modified July 1, 2019 10:12 AM

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