Per Ole Iversen

• Atukunda, Prudence; Muhoozi, Grace Kyamazima Mehangye; van den Broek, Tim; Kort, Remco; Diep, Lien My; Kaaya, Archileo; Iversen, Per Ole & Westerberg, Ane Cecilie (2019). Child development, growth and microbiota: follow-up of a randomized education trial in Uganda. Journal of Global Health.  ISSN 2047-2978.  9(1), s 1- 11 . doi: 10.7189/jogh.09.010431
• Atukunda, Prudence; Muhoozi, Grace Kyamazima Mehangye; Westerberg, Ane Cecilie & Iversen, Per Ole (2019). Nutrition, Hygiene and Stimulation Education for Impoverished Mothers in Rural Uganda: Effect on Maternal Depression Symptoms and Their Associations to Child Development Outcomes. Nutrients.  ISSN 2072-6643.  11(7) . doi: 10.3390/nu11071561
• Blakstad, Elin Wahl; Korpela, Katri; Lee, Sindre; Nakstad, Britt; Moltu, Sissel; Strømmen, Kenneth; Rønnestad, Arild Erlend; Brække, Kristin; Iversen, Per Ole; de Vos, Willem M. & Drevon, Christian A (2019). Enhanced nutrient supply and intestinal microbiota development in very low birth weight infants. Pediatric Research.  ISSN 0031-3998. . doi: 10.1038/s41390-019-0412-x
• Hjertholm, Katrine Gjermundnes; Holmboe-Ottesen, Gerd; Iversen, Per Ole; Mdala, Ibrahimu; Munthali, Alister; Maleta, Kenneth; Shi, Zumin; Ferguson, Elaine & Kamudoni, Penjani Rhoda (2019). Seasonality in associations between dietary diversity scores and nutrient adequacy ratios among pregnant women in rural Malawi - a cross-sectional study. Food & Nutrition Research.  ISSN 1654-6628. . doi: 10.29219/fnr.v63.2712
• James, William Philip Trehearne; Johnson, Richard J.; Speakman, John Roger; Wallace, Douglas C.; Frühbeck, Gema; Iversen, Per Ole & Stover, Patrick J. (2019). Nutrition and its role in human evolution. Journal of Internal Medicine.  ISSN 0954-6820.  285(5), s 533- 549 . doi: 10.1111/joim.12878
• Lien, Katarina; Johansen, Bjørn; Veierød, Marit Bragelien; Haslestad, Annicke Stranda; Bøhn, Siv Kjølsrud; Melsom, Morten Nissen; Kardel, Kristin Reimers & Iversen, Per Ole (2019). Abnormal blood lactate accumulation during repeated exercise testing in myalgic encephalomyelitis/chronic fatigue syndrome. Physiological Reports.  ISSN 2051-817X.  7(11) . doi: 10.14814/phy2.14138
• Rukundo, Peter Milton; Byaruhanga, Rukooko; Andreassen, Bård A. & Iversen, Per Ole (2019). Housing, water and sanitation implications on food insecurity and diet diversity in landslide affected communities: a cross-sectional survey of two districts in Uganda. Clinical Nutrition ESPEN.  ISSN 2405-4577.  33, s 47- 56 . doi: 10.1016/j.clnesp.2019.07.010
• Savikj, Mladen; Kostovski, Emil; Lundell, Leonidas S.; Iversen, Per Ole; Massart, J & Widegran, Ulrika (2019). Altered oxidative stress and antioxidant defence in skeletal muscle during the first year following spinal cord injury. Physiological Reports.  ISSN 2051-817X.  7(16) . doi: 10.14814/phy2.14218
• Skaarud, Kristin Aneta Joan; Veierød, Marit Bragelien; Lergenmuller, Simon; Bye, Asta; Iversen, Per Ole & Tjønnfjord, Geir Erland (2019). Body weight, body composition and survival after 1 year: follow-up of a nutritional intervention trial in allo-HSCT recipients. Bone Marrow Transplantation.  ISSN 0268-3369. . doi: 10.1038/s41409-019-0638-6
• Berg, Tone; Magala-Nyago, Christine & Iversen, Per Ole (2018). Nutritional status among adolescent girls in children's homes: Anthropometry and dietary patterns. Clinical Nutrition.  ISSN 0261-5614.  37(3), s 926- 933 . doi: 10.1016/j.clnu.2017.03.020
• Chortatos, Arthur; Iversen, Per Ole; Haugen, Margaretha; Eberhard-Gran, Malin; Bjelland, Elisabeth Krefting & Veierød, Marit Bragelien (2018). Nausea and vomiting in pregnancy - association with pelvic girdle pain during pregnancy and 4-6 months post-partum. BMC Pregnancy and Childbirth.  ISSN 1471-2393.  18 . doi: 10.1186/s12884-018-1764-7 Full text in Research Archive.
• Hjertholm, Katrine; Iversen, Per Ole; Holmboe-Ottesen, Gerd; Mdala, Ibrahimu; Munthali, Alister; Maleta, Kenneth; Shi, Zumin; Ferguson, Elaine & Kamudoni, Penjani Rhoda (2018). Maternal dietary intake during pregnancy and its association to birth size in rural Malawi – a cross-sectional study. Maternal and Child Nutrition.  ISSN 1740-8695.  14(1) . doi: 10.1111/mcn.12433
• Jagjit, Bhamra Singh; Iversen, Per Ole; Tjønnfjord, Geir Erland; Akkøk, Cigdem Ahaein & Titze, Thomas Larsen (2018). A case of post-transfusion purpura with severe refractory thrombocytopenia but no cutaneous manifestations. Case reports in hematology.  ISSN 2090-6560. . doi: 10.1155/2018/8187659
• Korpela, Katri; Blakstad, Elin Wahl; Moltu, Sissel; Strømmen, Kenneth; Nakstad, Britt; Rønnestad, Arild Erlend; Brække, Kristin; Iversen, Per Ole; Drevon, Christian A & de Vos, Willem M. (2018). Intestinal microbiota development and gestational age in preterm neonates. Scientific Reports.  ISSN 2045-2322.  8:2453, s 1- 9 . doi: 10.1038/s41598-018-20827-x Full text in Research Archive.
• Kostovski, Emil; Frigato, E; Savikj, Mladen; Dahm, Anders Erik A; Sandset, Per Morten; Mowinckel, Marie-Christine; Skretting, Grethe; Østerud, Bjarne; Bertolucci, C & Iversen, Per Ole (2018). Normalization of disrupted clock gene expression in males with tetraplegia: a crossover randomized placebo-controlled trial of melatonin supplementation. Spinal Cord.  ISSN 1362-4393.  s 1- 8 . doi: 10.1038/s41393-018-0176-x Full text in Research Archive.
• Kverneland, Magnhild; Molteberg, Ellen; Iversen, Per Ole; Veierød, Marit Bragelien; Taubøll, Erik; Selmer, Kaja Kristine & Nakken, Karl Otto (2018). Effect of modified Atkins diet in adults with drug-resistant focal epilepsy: A randomized clinical trial. Epilepsia.  ISSN 0013-9580.  59(8), s 1567- 1576 . doi: 10.1111/epi.14457
• Lundell, Leonidas S.; Savikj, Mladen; Kostovski, Emil; Iversen, Per Ole; Zierath, Juleen R.; Krook, Anna; Chibalin, Alexander V. & Widegren, Ulrika (2018). Protein translation, proteolysis and autophagy in human skeletal muscle atrophy after spinal cord injury. Acta Physiologica.  ISSN 1748-1708.  223(3) . doi: 10.1111/apha.13051 Show summary

  Aim: Spinal cord injury-induced loss of skeletal muscle mass does not progress linearly. In humans, peak muscle loss occurs during the first 6 weeks postinjury, and gradually continues thereafter. The aim of this study was to delineate the reg- ulatory events underlying skeletal muscle atrophy during the first year following spinal cord injury. Methods: Key translational, autophagic and proteolytic proteins wer e analysed by immunoblotting of human vastus lateralis muscle obtained 1, 3 and 12 months following spinal cord injury. Age-matched able-bodied control subjects were also studied. Results: Several downstream targe ts of Akt signalling decreased after spinal cord injury in skeletal muscle, without changes in resting Akt Ser 473 and Akt Thr 308 phosphorylation or total Akt protein. Abundance of mTOR protein and mTOR Ser 2448 phosphorylation, as well as FOXO1 Se r 256 phosphorylation and FOXO3 protein, decreased in response to spinal cord injury, coincident with attenuated protein abundance of E3 ubiquitin ligases, MuRF1 and MAFbx. S6 protein and Ser 235/236 phosphorylation, as well as 4E-BP1 Thr 37/46 phosphorylation, increased transiently after spinal cord injury, indicating higher levels of protein translation early after injury. Protein abundance of LC3-I and LC3-II decreased 3 months postinjury as compared with 1 month postinjury, but not compared to able-bodied control subjects, indicating lower levels of autophagy. Proteins regulating protea- somal degradation were stabl y increased in response to spinal cord injury. Conclusion: Together, these data provide indirect evidence suggesting that pro- tein translation and autophagy transiently increase, while whole proteolysis remains stably higher in skeletal muscle within the first year after spinal cord injury.

• Muhoozi, Grace Kyamazima Mehangye; Atukunda, Prudence; Diep, Lien My; Mwadime, Robert; Kaaya, Archileo; Skaare, Anne B; Willumsen, Tiril; Westerberg, Ane Cecilie & Iversen, Per Ole (2018). Nutrition, hygiene, and stimulation education to improve growth, cognitive, language, and motor development among infants in Uganda: A cluster-randomized trial. Maternal and Child Nutrition.  ISSN 1740-8695.  14(2) . doi: 10.1111/mcn.12527
• Muhoozi, Grace Kyamazima Mehangye; Atukunda, Prudence; Skaare, Anne B; Willumsen, Tiril; Diep, Lien My; Westerberg, Ane Cecilie & Iversen, Per Ole (2018). Effects of nutrition and hygiene education on oral health and growth among toddlers in rural Uganda: follow-up of a cluster-randomised controlled trial. Tropical medicine & international health.  ISSN 1360-2276.  23(4), s 391- 404 . doi: 10.1111/tmi.13036
• Nahalomo, Aziiza; Iversen, Per Ole; Rukundo, Milton Peter; Kaaya, Archileo; Kikafunda, Joyce; Eide, Wenche Barth; Marais, Maritha; Wamala, Edward & Kabahenda, Margaret (2018). Realization of the right to adequate food and the nutritional status of land evictees: A case for mothers/caregivers and their children in rural Central Uganda. BMC International Health and Human Rights.  ISSN 1472-698X.  18:21, s 1- 13 . doi: 10.1186/s12914-018-0162-6
• Nesvold, Marianne Bakke; Jensen, Janicke Liaaen; Hove, Lene Hystad; Singh, Preet Bano; Young, Alix; Palm, Øyvind; Andersen, Lene Frost; Carlsen, Monica Hauger & Iversen, Per Ole (2018). Dietary intake, body composition and oral health parameters among female patients with primary Sjögren’s syndrome. Nutrients.  ISSN 2072-6643.  10:866(7), s 1- 12 . doi: 10.3390/nu10070866 Full text in Research Archive.
• Ngari, Moses M.; Iversen, Per Ole; Thitiri, Johnstone; Mwalekwa, Laura; Timbwa, Molline; Fegan, Greg W. & Berkley, James Alexander (2018). Linear growth following complicated severe malnutrition: 1-year follow-up cohort of Kenyan children. Archives of Disease in Childhood.  ISSN 0003-9888.  s 1- 7 . doi: 10.1136/archdischild-2018-315641
• Ngari, Moses M.; Mwalekwa, Laura; Timbwa, Molline; Hamid, Fauzat; Ali, Rehema; Iversen, Per Ole; Fegan, Greg W. & Berkley, James A. (2018). Changes in susceptibility to life-threatening infections after treatment for complicated severe malnutrition in Kenya. American Journal of Clinical Nutrition.  ISSN 0002-9165.  107(4), s 626- 634 . doi: 10.1093/ajcn/nqy007
• Olafsen, Monica; Rukooko, Byaruhanga; Iversen, Per Ole & Andreassen, Bård A. (2018). Examination of the roles and capacities of duty bearers responsible for protecting the human rights to adequate food, nutritional health and wellbeing in Ugandan children's homes. BMC International Health and Human Rights.  ISSN 1472-698X.  18 . doi: 10.1186/s12914-018-0156-4
• Savikj, Mladen; Ruby, Maxwell A.; Kostovski, Emil; Iversen, Per Ole; Zierath, Juleen R.; Krook, Anna & Widegren, Ulrika (2018). Retained differentiation capacity of human skeletal muscle satellite cells from spinal cord-injured individuals. Physiological Reports.  ISSN 2051-817X.  6(12) . doi: 10.14814/phy2.13739
• Skaarud, Kristin Aneta Joan; Hjermstad, Marianne Jensen; Bye, Asta; Veierød, Marit Bragelien; Gudmundstuen, Anne Marte; Lundin, Knut Erik Aslaksen; Distante, Sonia; Brinch, Lorentz; Tjønnfjord, Geir Erland & Iversen, Per Ole (2018). Effects of individualized nutrition after allogeneic hematopoietic stem cell transplantation following myeloablative conditioning; a randomized controlled trial. Clinical Nutrition ESPEN.  ISSN 2405-4577.  28, s 59- 66 . doi: 10.1016/j.clnesp.2018.08.002
• Steffensen, Inger-Lise; Frølich, Wenche; Dahl, Knut Helkås; Iversen, Per Ole; Lyche, Jan Ludvig; Lillegaard, Inger Therese L. & Alexander, Jan (2018). Benefit and risk assessment of increasing potassium intake by replacement of sodium chloride with potassium chloride in industrial food products in Norway. Food and Chemical Toxicology.  ISSN 0278-6915.  111, s 329- 340 . doi: 10.1016/j.fct.2017.11.044 Full text in Research Archive.
• Baranski, M; Rempelos, L; Iversen, Per Ole & Leifert, Carlo (2017). Effects of organic food consumption on human health; the jury is still out. Food & Nutrition Research.  ISSN 1654-6628.  61 . doi: 10.1080/16546628.2017.1287333 Full text in Research Archive.
• Gjevestad, Gyrd Omholt; Ottestad, Inger; Biong, Anne Sofie; Iversen, Per Ole; Retterstøl, Kjetil; Raastad, Truls; Skålhegg, Bjørn Steen; Ulven, Stine Marie & Holven, Kirsten Bjørklund (2017). Consumption of protein-enriched milk has minor effects on inflammation in older adults?A 12-week double-blind randomized controlled trial. Mechanisms of Ageing and Development.  ISSN 0047-6374.  162, s 1- 8 . doi: 10.1016/j.mad.2017.01.011 Full text in Research Archive. Show summary

  Introduction: Aging is associated with increased levels of circulating inflammatory markers and reduced muscle mass and strength. Objective: We investigated whether intake of protein-enriched milk for 12 weeks would influence markers of inflammation among adults ≥70 years of age with reduced physical strength. Methods: In a double-blind randomized controlled intervention study, subjects were randomly allocated into two groups, receiving a protein-enriched milk (2 × 20 g protein/d, n = 14, mean (±SD) age 76.9 ± 4.9 yrs) or an isocaloric carbohydrate drink (n = 17, age 77.7 ± 4.8 yrs) for 12 weeks. We measured serum and mRNA expression levels of inflammatory markers in PBMCs. Results: Significant differences in the mRNA expression of nuclear receptor subfamily, group H, member 3 (NR1H3, encoding the LXRα transcription factor) and interferon gamma (INFG) were observed between groups. The mRNA level of TNFRSF1A was significantly reduced, while the mRNA level of dipeptidyl-peptidase 4 (DPP4) was significantly increased, in the control group. The serum level of TNFα increased significantly in the control group, while sTNFRSF1A increased significantly in both groups, but with no significant differences between groups. Conclusion: Consumption of a low-fat, protein-enriched milk for 12 weeks had minor effects on inflammatory related markers in older adults compared to an isocaloric carbohydrate drink.

• Klohe, Katharina; Da Costa, Clarissa; Lien, Nanna; Holmboe-Ottesen, Gerd; Rychlik, Michael; Haavardsson, Ingeborg K; Stordalen, Gunhild A.; Singh, S; Engebretsen, Ingunn Marie S.; Iversen, Per Ole & Winkler, Andrea Sylvia (2017). Nutrition – A global challenge for health.. Tidsskrift for Den norske legeforening.  ISSN 0029-2001. . doi: 10.4045/tidsskr.17.0679
• Komperød, Maren Jeanette; Sommer, Christine; Mellin-Olsen, Tonje; Iversen, Per Ole; Røseth, Arne & Valeur, Jørgen (2017). Persistent symptoms in patients with Crohn’s disease in remission: An exploratory study on the role of diet. Scandinavian Journal of Gastroenterology.  ISSN 0036-5521.  53(5), s 573- 578 . doi: 10.1080/00365521.2017.1397736
• Ngari, Moses; Thitiri, J; Mwalekwa, L; Timbwa, M; Iversen, Per Ole; Fegan, Greg & Berkely, James (2017). The impact of rickets on growth and morbidity during recovery among children with complicated severe acute malnutrition in Kenya: A cohort study. Maternal and Child Nutrition.  ISSN 1740-8695.  14:e12569(2), s 1- 9 . doi: 10.1111/mcn.12569 Full text in Research Archive.
• Olsen, Maria Belland; Hildrestrand, Gunn Annette; Scheffler, Katja; Vinge, Leif Erik; Alfsnes, Katrine; Palibrk, Vuk; Wang, Junbai; Neurauter, Christine Gran; Gomez, Luisa Fernanda Luna; Johansen, Jostein; Øgaard, Jonas; Ohm, Ingrid Kristine; Slupphaug, Geir; Kusnierczyk, Anna; Fiane, Arnt E; Brorson, Sverre Henning; Zhang, Lili; Gullestad, Lars; Louch, William Edward; Iversen, Per Ole; Østlie, Ingunn; Klungland, Arne; Christensen, Geir Arve; Sjaastad, Ivar; Sætrom, Pål; Yndestad, Arne; Aukrust, Pål; Bjørås, Magnar & Finsen, Alexandra (2017). NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture. Cell reports.  ISSN 2211-1247.  18, s 82- 92 . doi: 10.1016/j.celrep.2016.12.009 Full text in Research Archive.
• Ottestad, Inger; Løvstad, Arne; Gjevestad, Gyrd Omholt; Hamarsland, Håvard; Saltyte-Benth, Jurate; Frost Andersen, Lene; Bye, Asta; Biong, Anne-Sofie; Retterstøl, Kjetil; Iversen, Per Ole; Raastad, Truls; Ulven, Stine Marie & Holven, Kirsten Bjørklund (2017). Intake of a Protein-Enriched Milk and Effects on Muscle Mass and Strength. A 12-Week Randomized Placebo Controlled Trial among Community-Dwelling Older Adults. The Journal of Nutrition, Health & Aging.  ISSN 1279-7707.  21, s 1160- 1169 . doi: 10.1007/s12603-016-0856-1
• Retterstøl, Kjetil; Narverud, Ingunn; Selmer, Randi; Berge, Knut Erik; Osnes, Ingvild; Ulven, Stine Marie; Halvorsen, Bente; Aukrust, Pål; Holven, Kirsten Bjørklund & Iversen, Per Ole (2017). Severe hypertriglyceridemia in Norway: prevalence, clinical and genetic characteristics. Lipids in Health and Disease.  ISSN 1476-511X.  16 . doi: 10.1186/s12944-017-0511-9 Full text in Research Archive.
• Strømmen, Kenneth; Haag, Alexander; Moltu, Sissel; Veierød, Marit Bragelien; Blakstad, Elin Wahl; Nakstad, Britt; Almaas, Astrid; Brække, Kristin; Rønnestad, Arild Erlend; Daniel, Hannelore; Drevon, Christian A & Iversen, Per Ole (2017). Enhanced nutrient supply to very low birth weight infants is associated with higher blood amino acid concentrations and improved growth. Clinical Nutrition ESPEN.  ISSN 2405-4577.  18, s 16- 22 . doi: 10.1016/j.clnesp.2017.01.003
• Almaas, Astrid; Tamnes, Christian Krog; Nakstad, Britt; Henriksen, Christine; Grydeland, Håkon; Walhovd, Kristine B; Fjell, Anders Martin; Iversen, Per Ole & Drevon, Christian A (2016). Diffusion tensor imaging and behavior in premature infants at 8 years of age, a randomized controlled trial with long-chain polyunsaturated fatty acids. Early Human Development.  ISSN 0378-3782.  95, s 41- 46 . doi: 10.1016/j.earlhumdev.2016.01.021
• Andersson, Joanna; Hulander, Erik; Elisabet, Rothenberg & Iversen, Per Ole (2016). EFFECT ON BODY WEIGHT, QUALITY OF LIFE AND APPETITE FOLLOWING INDIVIDUALIZED, NUTRITIONAL COUNSELLING TO HOME-LIVING ELDERLY AFTER REHABILITATION – AN OPEN RANDOMIZED TRIAL. The Journal of Nutrition, Health & Aging.  ISSN 1279-7707. . doi: 10.1007/s12603-016-0825-8
• Biegstraaten, Marieke; Cox, Timothy M; Belmatoug, Nadia; Berger, M; Collin-Histed, Tanya; Vom Dahl, Stephan; Di Rocco, Maja; Fraga, Maria; Giona, F; Giraldo, P; Hasanhodzic, M; Hughes, D; Iversen, Per Ole; Kiewiet, A; Lukina, E; Machazcka, M; Marinakis, T; Mengel, E; Pastores, Gregory M.; Pløckinger, U; Rosenbaum, Hanna; Cerratrice, C; Symeonidis, A; Szer, J; Timmerman, J; Tylki-Szymanska, A; Hubschman, M; Zafeiriou, D; Zimran, Ari & Hollak, C (2016). Management goals for type 1 Gaucher disease: An expert consensus document from the European working group on Gaucher disease. Blood Cells, Molecules & Diseases.  ISSN 1079-9796.  68, s 203- 208 . doi: 10.1016/j.bcmd.2016.10.008
• Blakstad, Elin Wahl; Moltu, Sissel; Nakstad, Britt; Veierød, Marit Bragelien; Strømmen, Kenneth; Juliusson, Petur Benedikt; Almaas, Astrid; Rønnestad, Arild Erlend; Brække, Kristin; Drevon, Christian A & Iversen, Per Ole (2016). Enhanced nutrition improves growth and increases blood adiponectin concentrations in very low birth weight infants :. Food & Nutrition Research.  ISSN 1654-6628.  60:33171, s 1- 11 . doi: 10.3402/fnr.v60.33171
• Bye, Asta; Wesseltoft-Rao, Nima; Iversen, Per Ole; Skjegstad, Grete S; Holven, Kirsten Bjørklund; Ulven, Stine Marie & Hjermstad, Marianne Jensen (2016). Alterations in inflammatory biomarkers and energy intake in cancer cachexia: a prospective study in patients with inoperable pancreatic cancer. Medical Oncology.  ISSN 1357-0560.  33(6) . doi: 10.1007/s12032-016-0768-2 Full text in Research Archive.
• Henriksen, Christine; Almaas, Astrid; Westerberg, Ane Cecilie; Drevon, Christian A; Iversen, Per Ole & Nakstad, Britt (2016). Growth, metabolic markers, and cognition in 8-year old children born prematurely, follow-up of a randomized controlled trial with essential fatty acids. European Journal of Pediatrics.  ISSN 0340-6199.  175(9), s 1165- 1174 . doi: 10.1007/s00431-016-2755-1
• Holen, Torgeir; Norheim, Frode; Gundersen, Thomas Erik; Mitry, Patricia; Linseisen, Jakob; Iversen, Per Ole & Drevon, Christian A (2016). Biomarkers for nutrient intake with focus on alternative sampling techniques. Genes & Nutrition.  ISSN 1555-8932.  11:12 . doi: 10.1186/s12263-016-0527-1
• Muhoozi, Grace Kyamazima Mehangye; Atukunda, Prudence; Mwadime, Robert; Iversen, Per Ole & Westerberg, Ane Cecilie (2016). Nutritional and developmental status among 6- to 8-month-old children in southwestern Uganda: a cross-sectional study. Food & Nutrition Research.  ISSN 1654-6628.  60:30270 . doi: 10.3402/fnr.v60.30270 Full text in Research Archive.
• Mundal, Liv; Veierød, Marit Bragelien; Halvorsen, Thomas; Holven, Kirsten Bjørklund; Ose, Leiv; Iversen, Per Ole; Tell, Grethe Seppola; Leren, Trond Paul & Retterstøl, Kjetil (2016). Cardiovascular disease in patients with genotyped familial hypercholesterolemia in Norway during 1994-2009, a registry study. European Journal of Preventive Cardiology.  ISSN 2047-4873.  23(18), s 1962- 1969 . doi: 10.1177/2047487316666371 Show summary

  BACKGROUND: Familial hypercholesterolaemia increases the risk for cardiovascular disease. The primary aim of the present study was to describe sex differences in incidence and prevalence of cardiovascular disease leading to hospitalisation in a complete cohort of genotyped familial hypercholesterolaemia patients. DESIGN AND METHODS: In this registry study data on 5538 patients with verified genotyped familial hypercholesterolaemia were linked to data on all Norwegian cardiovascular disease hospitalisations, and hospitalisations due to pre-eclampsia/eclampsia, congenital heart defects and diabetes. RESULTS: During 1994-2009 a total of 1411 of familial hypercholesterolaemia patients were hospitalised, and ischaemic heart disease was reported in 90% of them. Mean (SD) age at first hospitalisation and first re-hospitalisation was 45.1 (16.5) and 47.6 (16.3) years, respectively, with no sex differences (P = 0.66 and P = 0.93, respectively). More men (26.9%) than women (24.1%) with familial hypercholesterolaemia were hospitalised (P = 0.02). The median (25th-75th percentile) number of hospital admissions was four (two to seven) per familial hypercholesterolaemia patient, with no sex differences (P = 0.87). Despite having familial hypercholesterolaemia at the time of hospitalisation, the diagnosis of familial hypercholesterolaemia was registered in only 45.7% of the patients at discharge. CONCLUSION: Most cardiovascular disease hospitalisations were due to ischaemic heart disease. Familial hypercholesterolaemia patients were first time hospitalised at age 45.1 years, with no significant sex differences in age, which are important novel findings. The awareness and registration of the familial hypercholesterolaemia diagnosis during the hospital stays were disturbingly low.

• Nordheim, Trond; Rustøen, Tone; Iversen, Per Ole & Nakstad, Britt (2016). Quality of life in parents of preterm infants in a randomized nutritional intervention trial. Food & Nutrition Research.  ISSN 1654-6628.  60, s 7 . doi: 10.3402/fnr.v60.32162
• Ottestad, Inger; Løvstad, Amund T.; Gjevestad, Gyrd Omholt; Hamarsland, Håvard; Saltyte Benth, Jurate; Andersen, Lene Frost; Bye, Asta; Biong, Anne Sofie; Retterstøl, Kjetil; Iversen, Per Ole; Raastad, Truls; Ulven, Stine Marie & Holven, Kirsten Bjørklund (2016). Intake of a protein-enriched milk and effects on muscle mass and strength. A 12-week randomized placebo controlled trial among community-dwelling older adults. The Journal of Nutrition, Health & Aging.  ISSN 1279-7707.  21, s 1160- 1169 . doi: 10.1007/s12603-016-0856-1
• Rukundo, Peter Milton; Andreassen, Bård A.; Kikafunda, Joyce; Rukooko, Byaruhanga; Oshaug, Arne & Iversen, Per Ole (2016). Household food insecurity and diet diversity after the major 2010 landslide disaster in Eastern Uganda: a cross-sectional survey.. British Journal of Nutrition.  ISSN 0007-1145.  115(4), s 718- 729 . doi: 10.1017/S0007114515004961 Full text in Research Archive.
• Rukundo, Peter Milton; Oshaug, Arne; Andreassen, Bård A.; Kikafunda, Joyce; Rukooko, Byaruhanga & Iversen, Per Ole (2016). Food variety consumption and household food insecurity coping strategies after the 2010 landslide disaster - the case of Uganda. Public Health Nutrition.  ISSN 1368-9800.  19(17), s 3197- 3209 . doi: 10.1017/S1368980016001397
• Skarpengland, Tonje; Holm, Sverre; Scheffler, Katja; Gregersen, Ida; Dahl, Tuva Børresdatter; Suganthan, Rajikala; Segers, Filip; Østlie, Ingunn; Otten, Jeroen J.T.; Gomez, Luisa Fernanda Luna; Ketelhuth, Daniel F.J.; Lundberg, Anna M.; Neurauter, Christine Gran; Hildrestrand, Gunn Annette; Skjelland, Mona; Bjørndal, Bodil; Svardal, Asbjørn M.; Iversen, Per Ole; Hedin, Ulf; Nygård, Ståle; Olstad, Ole Kristoffer; Krohg-Sørensen, Kirsten; Slupphaug, Geir; Eide, Lars; Kusnierczyk, Anna; Folkersen, Lasse; Ueland, Thor; Berge, Rolf Kristian; Hansson, Göran K.; Biessen, Erik A.L.; Halvorsen, Bente; Bjørås, Magnar & Aukrust, Pål (2016). Neil3-dependent base excision repair regulates lipid metabolism and prevents atherosclerosis in Apoe-deficient mice. Scientific Reports.  ISSN 2045-2322.  6:28337 . doi: 10.1038/srep28337
• Strømmen, Kenneth; Lyche, Jan Ludvig; Blakstad, Elin Wahl; Moltu, Sissel; Veierød, Marit Bragelien; Almaas, Astrid; Sakhi, Amrit Kaur; Thomsen, Cathrine; Nakstad, Britt; Brække, Kristin; Rønnestad, Arild Erlend; Drevon, Christian A & Iversen, Per Ole (2016). Increased levels of phthalates in very low birth weight infants with septicemia and bronchopulmonary dysplasia. Environment International.  ISSN 0160-4120.  89-90, s 228- 234 . doi: 10.1016/j.envint.2016.01.024
• Vogt, Line Erikstad; Rukooko, Byaruhanga; Iversen, Per Ole & Eide, Wenche Barth (2016). Human rights dimensions of food, health and care in children's homes in Kampala, Uganda - A qualitative study. BMC International Health and Human Rights.  ISSN 1472-698X.  16(1) . doi: 10.1186/s12914-016-0086-y
• Almaas, Astrid; Tamnes, Christian Krog; Nakstad, Britt; Henriksen, Christine; Walhovd, Kristine B; Fjell, Anders Martin; Due-Tønnessen, Paulina; Drevon, Christian A & Iversen, Per Ole (2015). Long-chain polyunsaturated fatty acids and cognition in VLBW infants at 8 years: An RCT. Pediatrics.  ISSN 0031-4005.  135(6), s 972- 980 . doi: 10.1542/peds.2014-4094
• Blakstad, Elin Wahl; Strømmen, Kenneth; Moltu, Sissel; Wattam-Bell, John; Nordheim, Trond; Almaas, Astrid; Grønn, Morten; Rønnestad, Arild Erlend; Brække, Kristin; Iversen, Per Ole; Hofsten, Claes von; Veierød, Marit Bragelien; Westerberg, Ane Cecilie; Drevon, Christian A & Nakstad, Britt (2015). Improved visual perception in very low birth weight infants on enhanced nutrient supply. Neonatology.  ISSN 1661-7800.  108(1), s 30- 37 . doi: 10.1159/000381660
• Boon, Hanneke; Sjøgren, R; Massart, J; Egan, B; Kostovski, Emil; Iversen, Per Ole; Hjeltnes, Nils; Chibalin, Alexander V.; Widegren, Ulrika & Zierath, J. R. (2015). MicroRNA-208b progressively declines after spinal cord injury in humans and is inversely related to myostatin expression.. Physiological Reports.  ISSN 2051-817X.  3:e12622(11), s 1- 10 . doi: 10.14814/phy2.12622
• Chortatos, Arthur; Haugen, Margaretha; Iversen, Per Ole; Vikanes, Åse Vigdis; Eberhard-Gran, Malin; Bjelland, Elisabeth Krefting; Magnus, Per & Veierød, Marit Bragelien (2015). Pregnancy complications and birth outcomes among women experiencing nausea only or nausea and vomiting during pregnancy in the Norwegian Mother and Child Cohort Study. BMC Pregnancy and Childbirth.  ISSN 1471-2393.  15 . doi: 10.1186/s12884-015-0580-6 Full text in Research Archive.
• Hansen, Tine Torjuul; Herselman, Marietjie; du Plessis, Lisanne; Daniels, Lynette; Bezuidenhout, Tirsa; van Niekerk, Cora; Truter, Laura & Iversen, Per Ole (2015). Evaluation of selected aspects of the Nutrition Therapeutic Programme offered to HIV-positive women of child-bearing age in Western Cape Province, South Africa. Southern African Journal of HIV Medicine.  ISSN 1608-9693.  16(1) . doi: 10.4102/sajhivmed.v16i1.338
• Iversen, Per Ole; Dahm, Anders Erik A; Skretting, Grethe; Mowinckel, Marie-Christine; Haslestad, Annicke Stranda; Østerud, Bjarne; Sandset, Per Morten & Kostovski, Emil (2015). Reduced peak, but no diurnal variation, in thrombin generation upon melatonin supplementation in tetraplegia. A randomised, placebo-controlled study.. Thrombosis and Haemostasis.  ISSN 0340-6245.  114(5), s 964- 968 . doi: 10.1160/TH15-05-0396

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• Haffner, Johan F W; Hager, Helle; Iversen, Per Ole & Nyquist, Emil (2018). Ikke nødvendig med injeksjoner ved vitamin B12-mangel. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  138(17) . doi: 10.4045/tidsskr.18.0668
• Hope, Sigrun; Nordstrøm, Marianne; Retterstøl, Kjetil; Iversen, Per Ole & Kolset, Svein Olav (2018). Retten til et helsefremmende kosthold for personer med utviklingshemning. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  138(2), s 122- 123 . doi: 10.4045/tidsskr.17.0985
• Kolset, Svein Olav; Nordstrøm, Marianne; Hope, Sigrun; Retterstøl, Kjetil & Iversen, Per Ole (2018). Securing rights and nutritional Health for persons with intellectual disabilities - a pressing challenge. Food & Nutrition Research.  ISSN 1654-6628.  62 . doi: 10.29219/fnr.v62.1268 Full text in Research Archive.
• Komperød, Maren Jeanette; Sommer, Christine; Mellin-Olsen, Tonje; Iversen, Per Ole; Røseth, Arne & Valeur, Jørgen (2018). Vedvarende symptomer hos pasienter med Crohns sykdom i remisjon: Har kostholdet betydning?.
• Haugen, Margaretha; Lillegaard, Inger Therese L.; Frøyland, Livar; Henjum, Sigrun; Holvik, Kristin; Løvik, Martinus; Skålhegg, Bjørn Steen; Stea, Tonje Holte; Strand, Tor A & Iversen, Per Ole (2017). Assessment of vitamin B6 intake in relation to tolerable upper intake Levels. Opinion of the Panel on Nutrition, Dietetic Products, Novel Food and Allergy of the Norwegian Scientific Committee for Food Safety. VKM Report. 2017:03. Full text in Research Archive.
• Henjum, Sigrun; Frøyland, Livar; Haugen, Margaretha; Holvik, Kristin; Løvik, Martinus; Skålhegg, Bjørn Steen; Stea, Tonje Holte; Strand, Tor A & Iversen, Per Ole (2017). Risk assessment of "other substances" – L-aspartic acid. Opinion of the Panel on Nutrition, Dietetic Products, Novel Food and Allergy of the Norwegian Scientific Committee for Food Safety. VKM Report. 2017:11. Full text in Research Archive.
• Henriksen, Christine; Almaas, Astrid; Westerberg, Ane Cecilie; Drevon, Christian A; Iversen, Per Ole & Nakstad, Britt (2017). Growth, metabolic profile and IQ in 8 years old children born preterm: Follow-up of an RCT with essential fatty acids (foredraget ble holdt på norsk).
• Løvik, Martinus; Frøyland, Livar; Haugen, Margaretha; Henjum, Sigrun; Holvik, Kristin; Skålhegg, Bjørn Steen; Stea, Tonje Holte; Strand, Tor A & Iversen, Per Ole (2017). Risk assessment of "other substances" – L-threonine. Opinion of the Panel on Nutrition, Dietetic Products, Novel Food and Allergy of the Norwegian Scientific Committee for Food Safety. VKM Report. 2017:10. Full text in Research Archive.
• Strand, Tor A; Lillegaard, Inger Therese L.; Frøyland, Livar; Haugen, Margaretha; Henjum, Sigrun; Holvik, Kristin; Løvik, Martinus; Skålhegg, Bjørn Steen; Stea, Tonje Holte & Iversen, Per Ole (2017). Assessment of iron intake in relation to tolerable upper intake Levels. Opinion of the Panel on Nutrition, Dietetic Products, Novel Food and Allergy of the Norwegian Scientific Committee for Food Safety. VKM Report. 2017:05. Full text in Research Archive.
• Strand, Tor A; Lillegaard, Inger Therese L.; Frøyland, Livar; Haugen, Margaretha; Henjum, Sigrun; Holvik, Kristin; Løvik, Martinus; Skålhegg, Bjørn Steen; Stea, Tonje Holte & Iversen, Per Ole (2017). Assessment of zinc intake in relation to tolerable upper intake Levels. Opinion of the Panel on Nutrition, Dietetic Products, Novel Food and Allergy of the Norwegian Scientific Committee for Food Safety. VKM Report. 2017:06. Full text in Research Archive.
• Andersen, Lene Frost; Andreassen, Åshild Kristine; Elvevoll, Edel Oddny; Hemre, Gro Ingunn; Hjeltnes, Brit; Hofshagen, Merete; Iversen, Per Ole; Krogdahl, Åshild; Källqvist, Torsten; Rafoss, Trond; Skaar, Ida; Skåre, Janneche Utne; Sorteberg, Hilde-Gunn Opsahl; Steffensen, Inger-Lise; Vandvik, Vigdis; Wasteson, Yngvild & Alexander, Jan (2016). Research needs and data gaps of importance for food safety and protection of biodiversity. From VKM’s scientific opinions in the period 2005 - 2015. Report from the Scientific Steering Committee of the Norwegian Scientific Committee for Food Safety. VKM Report. 2016: 48. Full text in Research Archive.
• Andersen, Lene Frost; Elvevoll, Edel Oddny; Hemre, Gro Ingunn; Hjeltnes, Brit; Hofshagen, Merete; Iversen, Per Ole; Krogdahl, Åshild; Källqvist, Torsten; Rafoss, Trond; Skaar, Ida; Skåre, Janneche Utne; Sorteberg, Hilde-Gunn Opsahl; Steffensen, Inger-Lise; Vandvik, Vigdis; Wasteson, Yngvild & Alexander, Jan (2016). Kunnskapsbehov av betydning for mattrygghet og biologisk mangfold. Oppsummering fra VKMs vitenskapelige uttalelser i perioden 2005 – 2015. Rapport fra Hovedkomiteen, Vitenskapskomiteen for Mattrygghet. VKM Report. 2016: 46. Full text in Research Archive.
• Andersen, Lene Frost; Elvevoll, Edel Oddny; Hemre, Gro Ingunn; Hjeltnes, Brit; Hofshagen, Merete; Iversen, Per Ole; Krogdahl, Åshild; Källqvist, Torsten; Rafoss, Trond; Skaar, Ida; Skåre, Janneche Utne; Sorteberg, Hilde-Gunn Opsahl; Steffensen, Inger-Lise; Vandvik, Vigdis; Wasteson, Yngvild & Alexander, Jan (2016). Research needs and data gaps of importance for food safety and protection of biodiversity. Summary report from VKM’s scientific opinions in the period 2005 - 2015. The Scientific Steering Committee of the Norwegian Scientific Committee for Food Safety. VKM Report. 2016: 47. Full text in Research Archive.
• Aronsen, Jan Magnus; Singbrant, Sofie; Christensen, Geir Arve & Iversen, Per Ole (2016). Evidence for splenic stress-induced erythropoiesis in mice with post-infarction heart failure.
• Frøyland, Livar; Haugen, Margaretha; Henjum, Sigrun; Holvik, Kristin; Løvik, Martinus; Skålhegg, Bjørn Steen; Stea, Tonje Holte; Strand, Tor A; Tell, Grethe S. & Iversen, Per Ole (2016). Risk assessment of "other substances" – L-tyrosine. Opinion of the Panel on Nutrition, Dietetic Products, Novel Food and Allergy of the Norwegian Scientific Committee for Food Safety. VKM Report. 2016:61. Full text in Research Archive.
• Frøyland, Livar; Haugen, Margaretha; Holvik, Kristin; Løvik, Martinus; Strand, Tor A; Tell, Grethe S. & Iversen, Per Ole (2016). Risk assessment of "other substances" – L-phenylalanine and DL-phenylalanine. Opinion of the Panel on Nutrition, Dietetic Products, Novel Food and Allergy of the Norwegian Scientific Committee for Food Safety. VKM Report. 2016:06. Full text in Research Archive.
• Gjevestad, Gyrd Omholt; Ottestad, Inger; Biong, Anne Sofie; Iversen, Per Ole; Retterstøl, Kjetil; Raastad, Truls; Skålhegg, Bjørn Steen; Ulven, Stine Marie & Holven, Kirsten Bjørklund (2016). Consumption of protein-enriched milk does not affect inflammation in elderly subjects - a 12 week double-blind randomized controlled trial.
• Haugen, Margaretha; Lillegaard, Inger Therese L.; Frøyland, Livar; Holvik, Kristin; Løvik, Martinus; Strand, Tor A; Tell, Grethe S. & Iversen, Per Ole (2016). Assessment of dietary intake of vitamin C and calcium in the Norwegian population. Opinion of the Panel on Nutrition, Dietetic Products, Novel Food and Allergy of the Norwegian Scientific Committee for Food Safety. VKM Report. 2016:16. Full text in Research Archive.
• Haugen, Margaretha; Lillegaard, Inger Therese L.; Strand, Tor A; Frøyland, Livar; Holvik, Kristin; Løvik, Martinus; Tell, Grethe S. & Iversen, Per Ole (2016). Risk assessment of magnesium in food supplements. Opinion of the Panel on Nutrition, Dietetic Products, Novel Food and Allergy of the Norwegian Scientific Committee for Food Safety. VKM Report. 2016:15. Full text in Research Archive.
• Henjum, Sigrun; Frøyland, Livar; Haugen, Margaretha; Holvik, Kristin; Løvik, Martinus; Skålhegg, Bjørn Steen; Stea, Tonje Holte; Strand, Tor A; Tell, Grethe S. & Iversen, Per Ole (2016). Risk assessment of "other substances" – L-lysine. Opinion of the Panel on Nutrition, Dietetic Products, Novel Food and Allergy of the Norwegian Scientific Committee for Food Safety. VKM Report. 2016:62. Full text in Research Archive.
• Holvik, Kristin; Frøyland, Livar; Haugen, Margaretha; Henjum, Sigrun; Løvik, Martinus; Skålhegg, Bjørn Steen; Stea, Tonje Holte; Strand, Tor A; Tell, Grethe S. & Iversen, Per Ole (2016). Risk assessment of "other substances" – L-proline. Opinion of the Panel on Nutrition, Dietetic Products, Novel Food and Allergy of the Norwegian Scientific Committee for Food Safety. VKM Report. 2016:60. Full text in Research Archive.
• Holvik, Kristin; Frøyland, Livar; Haugen, Margaretha; Løvik, Martinus; Strand, Tor A; Tell, Grethe S. & Iversen, Per Ole (2016). Risk assessment of "other substances" – L-tryptophan. Opinion of the Panel on Nutrition, Dietetic Products, Novel Food and Allergy of the Norwegian Scientific Committee for Food Safety. VKM Report. 2016:04. Full text in Research Archive.
• Holvik, Kristin; Iversen, Per Ole; Vaktskjold, Arild; Frøyland, Livar; Haugen, Margaretha; Løvik, Martinus; Skålhegg, Bjørn Steen; Stea, Tonje Holte; Strand, Tor A & Tell, Grethe S. (2016). Risk assessment of "other substances" – L-histidine. Opinion of the Panel on Nutrition, Dietetic Products, Novel Food and Allergy of the Norwegian Scientific Committee for Food Safety. VKM Report. 2016:24. Full text in Research Archive.
• Iversen, Per Ole; Frøyland, Livar; Haugen, Margaretha; Holvik, Kristin; Løvik, Martinus; Skålhegg, Bjørn Steen; Stea, Tonje Holte; Strand, Tor A & Tell, Grethe S. (2016). Risk assessment of "other substances" - creatine. Opinion of the Panel on Nutrition, Dietetic Products, Novel Food and Allergy of the Norwegian Scientific Committee for Food Safety. VKM Report. 2016:56. Full text in Research Archive.
• Iversen, Per Ole; Frøyland, Livar; Haugen, Margaretha; Holvik, Kristin; Løvik, Martinus; Strand, Tor A & Tell, Grethe S. (2016). Risk assessment of "other substances" - conjugated linoleic acids. Opinion of the Panel on Nutrition, Dietetic Products, Novel Food and Allergy of the Norwegian Scientific Committee for Food Safety. VKM Report. 2016:05. Full text in Research Archive.
• Løvik, Martinus; Frøyland, Livar; Haugen, Margaretha; Holvik, Kristin; Skålhegg, Bjørn Steen; Stea, Tonje Holte; Strand, Tor A; Tell, Grethe S. & Iversen, Per Ole (2016). Risk assessment of "other substances" - L-glutamine and L-glutamic acid. Opinion of the Panel on Nutrition, Dietetic Products, Novel Food and Allergy of the Norwegian Scientific Committee for Food Safety. VKM Report. 2016:25. Full text in Research Archive.
• Mundal, Liv; Veierød, Marit Bragelien; Halvorsen, Thomas; Holven, Kirsten Bjørklund; Ose, Leiv; Iversen, Per Ole; Tell, Grethe S.; Leren, Trond Paul & Retterstøl, Kjetil (2016). CARDIOVASCULAR DISEASE IN PATIENTS WITH FAMILIAL HYPERCHOLESTEROLEMIA IN NORWAY.
• Narverud, Ingunn; van Lennep, Jeanine Roeters; Christensen, Jacob J.; Versmissen, Jorie; Gran, Jon Michael; Iversen, Per Ole; Aukrust, Pål; Halvorsen, Bente; Ueland, Thor; Ulven, Stine Marie; Ose, Leiv; Veierød, Marit Bragelien; Sijbrands, Eric & Holven, Kirsten Bjørklund (2016). What is the impact of maternal inheritance of FH on lipids and CRP in children with FH?.
• Ottestad, Inger; Løvstad, Amund; Gjevestad, Gyrd Omholt; Hamarsland, Håvard; Benth, Jurate Saltyte; Andersen, Lene Frost; Bye, Asta; Biong, Anne Sofie; Retterstøl, Kjetil; Iversen, Per Ole; Raastad, Truls; Ulven, Stine Marie & Holven, Kirsten Bjørklund (2016). Intake of a protein-enriched milk and effects on muscle mass and strength. A 12-week randomized placebo controlled trial among community-dwelling older adults.
• Skålhegg, Bjørn Steen; Frøyland, Livar; Haugen, Margaretha; Holvik, Kristin; Løvik, Martinus; Stea, Tonje Holte; Strand, Tor A; Tell, Grethe S. & Iversen, Per Ole (2016). Risk assessment of "other substances" – L-leucine, L-isoleucine and L-valine, the branched chain amino acids (BCAA). Opinion of the Panel on Nutrition, Dietetic Products, Novel Food and Allergy of the Norwegian Scientific Committee for Food Safety. VKM Report. 2016:33. Full text in Research Archive.
• Stea, Tonje Holte; Frøyland, Livar; Haugen, Margaretha; Henjum, Sigrun; Holvik, Kristin; Løvik, Martinus; Skålhegg, Bjørn Steen; Strand, Tor A; Tell, Grethe S. & Iversen, Per Ole (2016). Risk assessment of "other substances" – L-serine. Opinion of the Panel on Nutrition, Dietetic Products, Novel Food and Allergy of the Norwegian Scientific Committee for Food Safety. VKM Report. 2016:59. Full text in Research Archive.
• Strand, Tor A; Frøyland, Livar; Haugen, Margaretha; Henjum, Sigrun; Holvik, Kristin; Skålhegg, Bjørn Steen; Stea, Tonje Holte; Tell, Grethe S. & Iversen, Per Ole (2016). Risk assessment of "other substances" – L-methionine. Statement of the Panel on Nutrition, Dietetic Products, Novel Food and Allergy of the Norwegian Scientific Committee for Food Safety. VKM Report. 2016:57. Full text in Research Archive.
• Tell, Grethe S.; Frøyland, Livar; Haugen, Margaretha; Henjum, Sigrun; Holvik, Kristin; Løvik, Martinus; Skålhegg, Bjørn Steen; Stea, Tonje Holte; Strand, Tor A & Iversen, Per Ole (2016). Risk assessment of "other substances" – glycine. Opinion of the Panel on Nutrition, Dietetic Products, Novel Food and Allergy of the Norwegian Scientific Committee for Food Safety. VKM Report. 2016:58.
• Tell, Grethe S.; Frøyland, Livar; Haugen, Margaretha; Holvik, Kristin; Løvik, Martinus; Strand, Tor A & Iversen, Per Ole (2016). Risk assessment of "other substances" - L-arginine and arginine alpha-ketoglutarate. Opinion of the Panel on Nutrition, Dietetic Products, Novel Food and Allergy of the Norwegian Scientific Committee for Food Safety. VKM Report. 2016:07. Full text in Research Archive.
• Bruzell, Ellen Merete; Granum, Berit; Hetland, Ragna Bogen; Husøy, Trine; Rohloff, Jens; Wicklund, Trude; Frøyland, Livar; Haugen, Margaretha; Holvik, Kristin; Løvik, Martinus; Strand, Tor A; Tell, Grethe S.; Vaktskjold, Arild; Iversen, Per Ole & Steffensen, Inger-Lise (2015). General principles for the risk assessment of “other substances” in food supplements and energy drinks. Report of the Panel on Food Additives, Flavourings, Processing Aids, Materials in Contact with Food and Cosmetics and the Panel on Nutrition, Dietetic Products, Novel Food and Allergy of the Norwegian Scientific Committee for Food Safety. VKM Report. 2015:31. Full text in Research Archive.
• Bye, Asta; Wesseltoft-Rao, Nima; Iversen, Per Ole; Holven, Kirsten Bjørklund & Hjermstad, Marianne Jensen (2015). Cachexia and inflammatory markers in patients with advanced pancreatic cancer.
• Chortatos, Arthur; Haugen, Margaretha; Iversen, Per Ole; Vikanes, Åse Vigdis; Eberhard-Gran, Malin; Bjelland, Elisabeth Krefting; Magnus, Per & Veierød, Marit Bragelien (2015). Erratum to Pregnancy complications and birth outcomes among women experiencing nausea only or nausea and vomiting during pregnancy in the Norwegian Mother and Child Cohort Study. [BMC Pregnancy Childbirth, 15, (2015), 138] doi: 10.1186/s12884-015-0580-6.. BMC Pregnancy and Childbirth.  ISSN 1471-2393.  15:167 . doi: 10.1186/s12884-015-0596-y
• Frølich, Wenche; Iversen, Per Ole; Lyche, Jan Ludvig; Dahl, Knut Helkås & Steffensen, Inger-Lise (2015). Benefit and risk assessment for human health of increasing potassium by replacement of sodium chloride with potassium chloride in industrial food products. EFSA Journal.  ISSN 1831-4732.  13(10), s 82
• Frøyland, Livar; Haugen, Margaretha; Holvik, Kristin; Løvik, Martinus; Strand, Tor A; Tell, Grethe S.; Vaktskjold, Arild & Iversen, Per Ole (2015). Risk assessment of “other substances” – eicosapentaenoic acid, docosapentaenoic acid and docosahexaenoic acid. Opinion of the Panel on Nutrition, Dietetic Products, Novel Food and Allergy of the Norwegian Scientific Committee for Food Safety. VKM Report. 2015:27. Full text in Research Archive.
• Haugen, Margaretha; Frølich, Wenche; Strand, Tor A; Tell, Grethe S.; Frøyland, Livar; Holven, Kirsten Bjørklund; Holvik, Kristin; Løvik, Martinus; Meltzer, Helle Margrete & Iversen, Per Ole (2015). Risk assessment of folic acid in food supplements. Scientific opinion of the Panel on Nutrition, Dietetic Products, Novel Food and Allergy. VKM Report. 2015:05. Full text in Research Archive.
• Hjertholm, Katrine Gjermundnes; Holmboe-Ottesen, Gerd; Iversen, Per Ole & Kamudoni, Penjani Rhoda (2015). Dietary quality and nutrient intake of pregnant mothers in Malawi, results from a pre-intervention study on nutrition counselling to increase birth weight. Show summary

  ABSTRACT Introduction: Malawi is burdened with one of the highest prevalence rates of low birth weight globally (1). The main cause is inadequate nutrition of the mother, which in turn affects growth and development of the foetus. Adequate nutrition during foetal stage and the first two years of life is essential for optimal cognitive and physical performance, and reduces the risk of non-communicable diseases in adulthood. Little is known about dietary intake among pregnant women in Malawi. Such information is needed in order to design appropriate interventions for nutrition counselling of pregnant mothers. The main objective of the present study was to assess the dietary adequacy of poor pregnant women in Mangochi district in Southern Malawi, by investigating nutrient intake and dietary diversity and to identify groups with the highest risk of inadequate diets. Methods: A total of 203 pregnant women in 28-35 weeks of gestation were interviewed by a questionnaire on sociodemographic characteristics, including possession of household assets. An interactive 24-hour recall method, based on pictures of local foods, was used to assess dietary intake. Intake of energy, fat, carbohydrate, protein, fibre, vitamin A, vitamin C, folate, vitamin B12, vitamin B6, niacin, thiamine, riboflavin, zinc, calcium and iron was calculated based on interviews on food quantities over three days. Data on non-quantified food intakes for seven days were collected by the same interactive 24-hour method but without portion sizes and used to calculate dietary diversity scores (DDS) as suggested by the FAO (2). The calculation was based on 12 food groups, but not including sweets and fats. Results: The intake was lower than the estimated average requirements (EAR) for all micronutrients except vitamin C. More than 90% of the participants had an intake of folate and riboflavin below the EAR. The overall nutrient adequacy ratio (NAR) was 0.73, with individual NARs ranging from 0.50 (vitamin B12) to 1.12 (vitamin C). The group had a mean DDS of 4.8 out of a maximum of 12. Those participants in the group with the highest DDS consumed more meat, eggs, and milk compared to the lowest and medium scoring groups. Those with secondary school education consumed 460.4 kcal more per day compared to those with primary level education. Linear multivariate regressions revealed that the household assets index was negatively associated with intake of protein, thiamine, iron, zinc and fibre (b= -0.29, b= -0.01, b= -0.24, b= -0.10 and b= -0.33, respectively). Vitamin B12 and calcium intakes were higher among the unmarried participants (0.7 micrograms and 183.5 milligrams, respectively) compared to those married. The DDS was also higher for the unmarried participants. There was a correlation coefficient of 0.28 (p<0.01) between the DDS and the nutrient adequacy, measured by the overall NAR. Conclusions: The dietary intake among pregnant women in Mangochi District was inadequate in regard to most micronutrients. Those with the highest dietary diversity score had higher energy intake and consumed more animal foods and thus had a higher intake of micronutrients. Low education was related to lower energy intake, whereas lower household asset index was related to higher intake of protein and some micronutrients – most likely due to higher intake of green leafy vegetables and whole grain maize among the poor. Nutrition intervention is needed among pregnant women and could be based on local foods to achieve recommended intake for most micronutrients.

• Hjertholm, Katrine Gjermundnes; Iversen, Per Ole; Holmboe-Ottesen, Gerd & Kamudoni, Penjani Rhoda (2015). Association between pregnancy dietary intake and birth weight among mother-infant dyads in Malawi, results from a pre-intervention study on nutrition counselling to increase birth weight. Show summary

  Introduction: Optimal dietary intake during pregnancy has been shown to be associated with better pregnancy outcomes including optimal birth weight and consequent neonatal survival (Siega-Riz et al. 2009). The benefits are shown to be higher among women who are undernourished at pregnancy (WHO 2006). This warrants the need to understand the local epidemiology of maternal nutrition in settings where undernutrition is a public health challenge. The objective of the present study was to examine the association between maternal dietary intake during pregnancy and infant birth weight Methods: Dietary intake of 203 pregnant women between 28 – 35 weeks gestation in a typical rural community in Malawi was studied. An interactive 24-hour recall method, based on pictures of local foods, was used to assess dietary intake (Food and Agriculture Organization 2012). Intake of energy, fat, carbohydrate, protein, fibre, vitamin A, vitamin C, folate, vitamin B12, vitamin B6, niacin, thiamine, riboflavin, zinc, calcium and iron was calculated based on interviews on food quantities over three days. Data on non-quantified food intakes for seven days, collected by the same interactive 24-hour method, were used to calculate food group intakes and dietary diversity scores (DDS). Birth weight of the study participants’ infants was measured in the health facilities where the participants gave birth. Measurements were collected only among 130 out of the 203 participants owing to losses due to follow up. Weights were measured nude in a supine position within one hour after delivery, using a Seca digital pediatric scale. Linear regression was used to examine the association between dietary intake (at both food and nutrient level) and birth weight. Results: The mean±SD birth weight was 3105±401g. Six percent of the infants had a low birth weight (<2500g). In unadjusted analyses birth weight was associated with intake of vitamin C (p=0.05), vitamin B12 (p=0.03), riboflavin (p=0.01), calcium (p=0.01). None of these nutrients yielded significant associations with birth weight, when adjusted for socio-demographic factors. However, riboflavin and energy showed a trend towards significance, p=0.09 and p=0.06 respectively. In crude analyses, eggs (p=0.04) and milk (p=0.01) intakes were associated with birth weight. However, after adjusting for energy, only milk intake remained (p<0.01) significant. Conclusion: A strong association between maternal milk intake during pregnancy and infant birth weight was observed in this study. Food based recommendations promoting optimal dietary intake during pregnancy, emphasizing intake of dairy products could be worthwhile in this setting. The association between birth weight and nutrient intake as such was not significant perhaps due to the inherent errors in measurement of nutrients for food composition tables. In addition the analyses were not adjusted for nutrient bioavailability of the foods, which may likely have been low for some micronutrients given that the diets were mostly plant based. The sample size was also reduced owing to losses due to follow up.

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