Yun Zhou

Principal Engineer - Division of Anatomy
Image of Yun Zhou
Norwegian version of this page
Phone +47-22851243
Room 1273
Username
Visiting address Sognsvannsveien 9 Domus Medica 0372 OSLO
Postal address Postboks 1105 Blindern 0317 OSLO
Other affiliations Faculty of Medicine (Student) Department of Education (Student)
Tags: Brain and nervous system, Molecular nutrition

Publications

  • Albertini, Giulia; Deneyer, L.; Hansen, Sigrid Ottestad; Zhou, Yun; Ates, G; Walrave, L; Demuyser, Thomas; Bentea, Eduard; Sato, Hideyo; De Bundel, D; Danbolt, Niels Christian; Massie, Ann & Smolders, Ilse (2018). Genetic deletion of xCT attenuates peripheral and central inflammation and mitigates LPS-induced sickness and depressive-like behavior in mice. Glia.  ISSN 0894-1491.  66(9), s 1845- 1861 . doi: 10.1002/glia.23343 Show summary
  • Hansen, Sigrid Ottestad; Hu, Qiu Xiang; Follin-Arbelet, Virginie; Bentea, Eduard; Sato, Hideyo; Massie, Ann; Zhou, Yun & Danbolt, Niels Christian (2018). The cystine-glutamate exchanger (xCT, Slc7a11) is expressed in significant concentrations in a subpopulation of astrocytes in the mouse brain.. Glia.  ISSN 0894-1491.  66(5), s 951- 970 . doi: 10.1002/glia.23294 Show summary
  • Hu, Qiu Xiang; Hansen, Sigrid Ottestad; Holmseth, Silvia; Hassel, Bjørnar; Danbolt, Niels Christian & Zhou, Yun (2018). Expression of glutamate transporters in mouse liver, kidney, and intestine. Journal of Histochemistry and Cytochemistry.  ISSN 0022-1554.  66(3), s 189- 202 . doi: 10.1369/0022155417749828 Show summary
  • Zhou, Yun; Dhaher, Roni; Parent, Maxime; Hu, Qiu Xiang; Hassel, Bjørnar; Yee, Siu-Pok; Hyder, Fahmeed; Gruenbaum, Shaun E.; Eid, Tore & Danbolt, Niels Christian (2018). Selective deletion of glutamine synthetase in the mouse cerebral cortex induces glial dysfunction and vascular impairment that precede epilepsy and neurodegeneration. Neurochemistry International.  ISSN 0197-0186.  s 1- 12 . doi: 10.1016/j.neuint.2018.07.009
  • Zhou, Yun; Hassel, Bjørnar; Eid, Tore & Danbolt, Niels Christian (2018). Axon-terminals expressing EAAT2 (GLT-1; Slc1a2) are common in the forebrain and not limited to the hippocampus. Neurochemistry International.  ISSN 0197-0186.  123, s 101- 113 . doi: 10.1016/j.neuint.2018.03.006
  • Danbolt, Niels Christian; Furness, David N & Zhou, Yun (2016). Neuronal vs glial glutamate uptake: Resolving the conundrum. Neurochemistry International.  ISSN 0197-0186.  98, s 29- 45 . doi: 10.1016/j.neuint.2016.05.009 Show summary
  • Danbolt, Niels Christian; Zhou, Yun; Furness, David N & Holmseth, Silvia (2016). Strategies for immunohistochemical protein localization using antibodies: What did we learn from neurotransmitter transporters in glial cells and neurons. Glia.  ISSN 0894-1491.  64(12), s 2045- 2064 . doi: 10.1002/glia.23027 Show summary
  • Eid, Tore; Gruenbaum, SE; Dhaher, R; Lee, T W; Zhou, Yun & Danbolt, Niels Christian (2016). The Glutamate-Glutamine Cycle in Epilepsy. Advances in neurobiology.  ISSN 2190-5215.  13, s 351- 400
  • Petr, Geraldine T; Sun, Yan; Frederick, Natalie M; Zhou, Yun; Dhamne, Sameer C; Hameed, Mustafa Q; Miranda, Clive; Bedoya, Edward A; Fischer, Kathryn D; Armsen, Wencke; Wang, Jianlin; Danbolt, Niels Christian; Rotenberg, Alexander; Aoki, Chiye J & Rosenberg, Paul A (2015). Conditional deletion of the glutamate transporter GLT-1 reveals that astrocytic GLT-1 protects against fatal epilepsy while neuronal GLT-1 contributes significantly to glutamate uptake into synaptosomes. Journal of Neuroscience.  ISSN 0270-6474.  35(13), s 5187- 5201 . doi: 10.1523/JNEUROSCI.4255-14.2015
  • Zhou, Yun; Kempson, S.A. & Danbolt, Niels Christian (2015). Betaine uptake with a focus on the betaine/GABA transporter. Food and Nutritional Components in Focus.  ISSN 2045-1695.  2015-January(7), s 76- 89
  • Bjørnsen, Lars Petter; Hadera, Mussie Ghezu; Zhou, Yun; Danbolt, Niels Christian & Sonnewald, Ursula (2014). The GLT-1 (EAAT2; Slc1a2) glutamate transporter is essential for glutamate homeostasis in the neocortex of the mouse. Journal of Neurochemistry.  ISSN 0022-3042.  128(5), s 641- 649 . doi: 10.1111/jnc.12509
  • Zhou, Yun & Danbolt, Niels Christian (2014). Glutamate as a neurotransmitter in the healthy brain. Journal of neural transmission.  ISSN 0300-9564.  121(8), s 799- 817 . doi: 10.1007/s00702-014-1180-8
  • Zhou, Yun; Waanders, LF; Holmseth, Silvia; Guo, C; Berger, Urs V; Li, Yuchuan; Lehre, Anne- Catherine W G; Lehre, Knut Petter Dæhlin & Danbolt, Niels Christian (2014). Proteome analysis and conditional deletion of the EAAT2 glutamate transporter provide evidence against a role of EAAT2 in pancreatic insulin secretion in mice. Journal of Biological Chemistry.  ISSN 0021-9258.  289(3), s 1329- 1344 . doi: 10.1074/jbc.M113.529065
  • Zhou, Yun; Wang, Xiaoyu; Tzingounis, Anastasios V; Danbolt, Niels Christian & Larsson, H Peter (2014). EAAT2 (GLT-1; slc1a2) glutamate transporters reconstituted in liposomes argues against heteroexchange being substantially faster than net uptake. Journal of Neuroscience.  ISSN 0270-6474.  34(40), s 13472- 13485 . doi: 10.1523/JNEUROSCI.2282-14.2014
  • Zhou, Yun & Danbolt, Niels Christian (2013). GABA and Glutamate Transporters in Brain. Frontiers in Endocrinology.  ISSN 1664-2392.  4 . doi: 10.3389/fendo.2013.00165
  • Zhou, Yun; Waanders, Leonie; Holmseth, Silvia; Guo, Caiying; Berger, Urs V; Li, Yuchuan; Lehre, Anne- Catherine W G; Lehre, Knut Petter Dæhlin & Danbolt, Niels Christian (2013). Proteome analysis and conditional deletion of the EAAT2 glutamate transporter provide evidence against a role of EAAT2 in pancreatic insulin secretion in mice. Journal of Biological Chemistry.  ISSN 0021-9258. . doi: 10.1074/jbc.M113.529065
  • Holmseth, Silvia; Dehnes, Yvette; Huang, YHH; Follin-Arbelet, Virginie; Verket, Nina Julie; Mylonakou, Maria-Niki; Plachez, C; Zhou, Yun; Furness, DN; Bergles, DE; Lehre, Knut Petter Dæhlin & Danbolt, Niels Christian (2012). The Density of EAAC1 (EAAT3) Glutamate Transporters Expressed by Neurons in the Mammalian CNS. Journal of Neuroscience.  ISSN 0270-6474.  32(17), s 6000- 6013 . doi: 10.1523/JNEUROSCI.5347-11.2012
  • Holmseth, Silvia; Zhou, Yun; Follin-Arbelet, Virginie; Lehre, Knut Petter Dæhlin; Bergles, Dwight E. & Danbolt, Niels Christian (2012). Specificity Controls for Immunocytochemistry: The Antigen Preadsorption Test Can Lead to Inaccurate Assessment of Antibody Specificity. Journal of Histochemistry and Cytochemistry.  ISSN 0022-1554.  60(3), s 174- 187 . doi: 10.1369/0022155411434828
  • Li, Yuchuan; Zhou, Yun & Danbolt, Niels Christian (2012). The Rates of Postmortem Proteolysis of Glutamate Transporters Differ Dramatically between Cells and between Transporter Subtypes. Journal of Histochemistry and Cytochemistry.  ISSN 0022-1554.  60(11), s 811- 821 . doi: 10.1369/0022155412458589
  • Zhou, Yun; Holmseth, Silvia; Guo, C; Hassel, Bjørnar; Höfner, G; Huitfeldt, Henrik; Wanner, KT & Danbolt, Niels Christian (2012). Deletion of the γ-aminobutyric acid transporter 2 (GAT2 and SLC6A13) gene in mice leads to changes in liver and brain taurine contents. Journal of Biological Chemistry.  ISSN 0021-9258.  287(42), s 35733- 35746 . doi: 10.1074/jbc.M112.368175
  • Zhou, Yun; Holmseth, Silvia; Hua, Rui; Lehre, Anne- Catherine W G; Olofsson, Anna Maria; Poblete-Naredo, Irais; Kempson, S.A. & Danbolt, Niels Christian (2012). The betaine-GABA transporter (BGT1, slc6a12) is predominantly expressed in the liver and at lower levels in the kidneys and at the brain surface. American Journal of Physiology - Renal, fluid and electrolyte physiology.  ISSN 0363-6127.  302(3), s F316- F328 . doi: 10.1152/ajprenal.00464.2011
  • Lehre, Anne- Catherine W G; Rowley, Nicole; Zhou, Yun; Holmseth, Silvia; Guo, Chungang; Holen, Torgeir; Hua, Rui; Laake, Petter; Olofsson, Anna Maria; Poblete-Naredo, Irais; Rusakov, Dimitri A.; Madsen, Karsten K.; Clausen, Rasmus P.; Schousboe, Arne; White, H. Steve & Danbolt, Niels Christian (2011). Deletion of the betaine-GABA transporter (BGT1; slc6a12) gene does not affect seizure thresholds of adult mice. Epilepsy Research.  ISSN 0920-1211.  95(1-2), s 70- 81 . doi: 10.1016/j.eplepsyres.2011.02.014
  • Furness, DN; Dehnes, Yvette; Akhtar, Aisha Qureshi; Rossi, DJ; Hamann, M; Grutle, Nina J.; Gundersen, Vidar; Holmseth, Silvia; Lehre, Knut Petter Dæhlin; Ullensvang, Kyrre; Wojewodzic, Marcin; Zhou, Yun; Attwell, D & Danbolt, Niels Christian (2008). A QUANTITATIVE ASSESSMENT OF GLUTAMATE UPTAKE INTO HIPPOCAMPAL SYNAPTIC TERMINALS AND ASTROCYTES: NEW INSIGHTS INTO A NEURONAL ROLE FOR EXCITATORY AMINO ACID TRANSPORTER 2 (EAAT2). Neuroscience.  ISSN 0306-4522.  157(1), s 80- 94 . doi: 10.1016/j.neuroscience.2008.08.043

View all works in Cristin

  • Danbolt, Niels Christian; Ottestad-Hansen, Sigrid; Hu, Qiu Xiang; Follin-Arbelet, Virginie; Bentea, Eduard; Sato, Hideyo; Massie, Ann & Zhou, Yun (2018). The cysteine-glutamate exchanger (xCT, slc7a11) is expressed in significant concentrations in a subpopulation of astrocytes in the mouse brain.
  • Gudmundsrud, Ruben; Ottestad-Hansen, Sigrid; Hu, Qiu Xiang; Danbolt, Niels Christian & Zhou, Yun (2018). The role of glutamate/cystine exchanger (slc7a11) in amyotrophic lateral sclerosis.
  • Zhou, Yun (2018). Glutamate uptake in nerve terminals.
  • Zhou, Yun (2018). Neuronal vs glial glutamate uptake: Resolving the conundrum.
  • Zhou, Yun; Hassel, Bjørnar; Eid, Tore & Danbolt, Niels Christian (2018). Axon-terminals expressing EAAT2 (GLT-1; slc1a2) are common in the forebrain and not limited to the hippocampus.
  • Danbolt, Niels Christian; Zhou, Yun; Dhaher, Roni; Parent, Maxime; Yee, Siu-Pok; Hyder, Fahmeed; Hu, Qiu Xiang & Eid, Tore (2017). Loss of glutamine synthetase initiates a sequence of neuropathological events that culminate in epilepsy and neurodegeneration.
  • Hu, Qiu Xiang; Danbolt, Niels Christian; Eid, Tore & Zhou, Yun (2017). Phenotypic differences between brain- and liver-specific glutamine synthetase knockout mice.
  • Ottestad-Hansen, Sigrid; Hu, Qiu Xiang; Follin-Arbelet, Virginie; Sato, Hideyo; Bentea, Eduard; Massie, Ann; Zhou, Yun & Danbolt, Niels Christian (2017). The cystine-glutamate exchanger (xCT, Slc7a11) is expressed in significant concentrations in a subpopulation of astrocytes in the mouse brain..
  • Hu, Qiu Xiang; Ottestad-Hansen, Sigrid; Kavanaugh, M.; Danbolt, Niels Christian & Zhou, Yun (2016). Vizualization of the EAAT3 glutamate transporter EAAC1 in mouse kidney and intestine.
  • Ottestad-Hansen, Sigrid; Zhou, Yun; Follin-Arbelet, Virginie; Sato, Hideyo; Massie, Ann & Danbolt, Niels Christian (2016). The localization of glutamate-cystine exchanger xCT (slc7a11) in mouse brain.
  • Danbolt, Niels Christian; Zhou, Yun; Xu, Ji & Khakh, Baljit (2015). Generation and characterization of BAC transgenic GABA transporter 2 (GAT2; slc6a13) tdTomato reporter mice.
  • Danbolt, Niels Christian; Zhou, Yun; Xu, Ji & Khakh, Baljit (2015). Generation and characterization of BAC transgenic GABA transporter 2 (GAT2; slc6a13) tdTomato reporter mice.
  • Wang, Helen; Dhaher, Roni; Farina, M.; Zhou, Yun; Yee, Siu-Pok; Danbolt, Niels Christian & Eid, Tore (2015). Brain site specific suppression of glutamine synthetase in mice using an adenoassociated virus knockout approach.
  • Wang, Helen; Dhaher, Roni; Farina, M.; Zhou, Yun; Yee, Siu-Pok; Danbolt, Niels Christian & Eid, Tore (2015). Brain site specific suppression of glutamine synthetase in mice using an adenoassociated virus knockout approach.
  • Zhou, Yun; Corbin, Karen; Xiang, Yi-Kong; Eskild, Winnie; Zeisel, Steven H. & Danbolt, Niels Christian (2015). The betaine-GABA transporter (BGT1; slc6a12) is not involved in the inactivation of transmitter GABA, but plays a role in preserving the choline levels in the liver.
  • Zhou, Yun; Corbin, Karen; Xiang, Yi-Kong; Eskild, Winnie; Zeisel, Steven H. & Danbolt, Niels Christian (2015). The betaine-GABA transporter (BGT1; slc6a12) may play its main roles in the liver rather than in the brain.
  • Kempson, SA; Zhou, Yun & Danbolt, Niels Christian (2014). The betaine/GABA transporter and betaine: Roles in brain, kidney, and liver. Frontiers in Physiology.  ISSN 1664-042X.  5 APR . doi: 10.3389/fphys.2014.00159
  • Zhou, Yun; Danbolt, Niels Christian & Kempson, S.A. (2014). The Betaine-GABA transporter, In Victor R. Preedy (ed.),  Betaine - Chemistry, Analysis, Function and Effects.  Royal Society of Chemistry.  ISBN 9781849738866.  The Betaine-GABA transporter.
  • Hadera, Mussie Ghezu; Bjørnsen, Lars Petter; Zhou, Yun; Sonnewald, Ursula & Danbolt, Niels Christian (2013). Impairment of glial-neuronal interaction in GLT-1 knockout mice: an NMR spectroscopy study. Journal of Neurochemistry.  ISSN 0022-3042.  125, s 109- 109
  • Hadera, Mussie Ghezu; Bjørnsen, Lars Petter; Zhou, Yun; Sonnewald, Ursula & Danbolt, Niels Christian (2013). Impairment of glial-neuronal interaction in GLT-1 knockout mice: an NMR spectroscopy study.
  • Danbolt, Niels Christian; Holmseth, Silvia; Dehnes, Yvette; Huang, Y.; Follin-Arbelet, Virginie; Grutle, N; Plachez, C.; Furness, D.; Zhou, Yun; Bergles, D & Lehre, Knut Petter Dæhlin (2011). QUANTIFICATION AND LOCALIZATION OF THE EAAC1 GLUTAMATE TRANSPORTER IN BRAIN. Glia.  ISSN 0894-1491.  59, s S66- S66
  • Zhou, Yun; Holmseth, Silvia; Holen, Torgeir & Danbolt, Niels Christian (2011). EVIDENCE AGAINST A ROLE OF THE BETAINE-GABA TRANSPORTER (BGT1, SLC6A12) IN THE CONTROL OF GABA RECEPTOR ACTIVATION. Glia.  ISSN 0894-1491.  59, s S69- S70

View all works in Cristin

Published Apr. 13, 2011 2:41 PM - Last modified May 15, 2018 2:01 PM

Research groups