Immune Responses in Rheumatic Diseases

About the group

We conduct in-depth analysis of immune cells in inflamed tissues and blood to uncover the underlying mechanisms of various rheumatic diseases, with a particular focus on joint inflammation and rheumatoid arthritis. Our goal is to pioneer new diagnostic tools and pinpoint therapeutic targets for improved treatment outcomes.

Recent publications

List from PubMed

A human autoimmune organoid model reveals IL-7 function in coeliac disease July 24, 2024 2:00 AM
Generation of circulating autoreactive pre-plasma cells fueled by naive B cells in celiac disease Apr. 5, 2024 2:00 AM
Gluten-Free Diet Induces Rapid Changes in Phenotype and Survival Properties of Gluten-Specific T Cells in Celiac Disease Mar. 29, 2024 1:00 AM
Identification of gluten T cell epitopes driving celiac disease Jan. 25, 2023 1:00 AM
Pathogenic T Cells in Celiac Disease Change Phenotype on Gluten Challenge: Implications for T-Cell-Directed Therapies Dec. 9, 2022 1:00 AM
KIR+CD8+ T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19 Mar. 8, 2022 1:00 AM
Phenotype-Based Isolation of Antigen-Specific CD4+ T Cells in Autoimmunity: A Study of Celiac Disease Feb. 4, 2022 1:00 AM
Human KIR + CD8 + T cells target pathogenic T cells in Celiac disease and are active in autoimmune diseases and COVID-19 Jan. 4, 2022 1:00 AM
Pathogenic T Cells in Celiac Disease Change Phenotype on Gluten Challenge: Implications for T-Cell-Directed Therapies Sep. 8, 2021 2:00 AM
Response to: "Some considerations about γδ and CD8+ T-cell responses in blood after gluten challenge in treated celiac disease" June 10, 2021 2:00 AM
Comprehensive Analysis of CDR3 Sequences in Gluten-Specific T-Cell Receptors Reveals a Dominant R-Motif and Several New Minor Motifs Apr. 30, 2021 2:00 AM
Circulating CD103+ γδ and CD8+ T cells are clonally shared with tissue-resident intraepithelial lymphocytes in celiac disease Mar. 3, 2021 1:00 AM
Single-cell TCR repertoire analysis reveals highly polyclonal composition of human intraepithelial CD8+ αβ T lymphocytes in untreated celiac disease Feb. 9, 2021 1:00 AM
Peptide-MHC class I and class II tetramers: From flow to mass cytometry Jan. 1, 2020 1:00 AM
CD38 expression on gluten-specific T cells is a robust marker of gluten re-exposure in coeliac disease Dec. 17, 2019 1:00 AM
Single-cell TCR sequencing of gut intraepithelial γδ T cells reveals a vast and diverse repertoire in celiac disease Nov. 16, 2019 1:00 AM
Therapeutic and Diagnostic Implications of T Cell Scarring in Celiac Disease and Beyond July 24, 2019 2:00 AM
Distinct phenotype of CD4+ T cells driving celiac disease identified in multiple autoimmune conditions Mar. 27, 2019 1:00 AM
Discriminative T-cell receptor recognition of highly homologous HLA-DQ2-bound gluten epitopes Nov. 21, 2018 1:00 AM
Disease-driving CD4+ T cell clonotypes persist for decades in celiac disease May 15, 2018 2:00 AM

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