Selected publications
✉ corresponding author (incl. co-corresponding)
Organelle identity & membrane compartmentalization
Peroxisomal core structures segregate diverse metabolic pathways (2025). Nature Communications 16(1): 1802. DOI: 10.1038/s41467-024-48105-4. ✉
Membrane identity & phosphoinositide control
A phosphoinositide and RAB switch controls early macropinocytosis (2021). bioRxiv (preprint). DOI: 10.1101/2021.11.03.467145. ✉
The phosphoinositide coincidence detector Phafin2 promotes macropinocytosis by coordinating actin organisation at forming macropinosomes (2021). Nature Communications 12(1): 6577. DOI: 10.1038/s41467-021-26724-1. ✉
JIP4 is recruited by the phosphoinositide-binding protein Phafin2 to promote recycling tubules on macropinosomes (2021). Journal of Cell Science 134(14): jcs258495. DOI: 10.1242/jcs.258495. ✉
Phosphoinositides in control of membrane dynamics (2016). Annual Review of Cell and Developmental Biology 32: 143–171. DOI: 10.1146/annurev-cellbio-111315-125349
Cancer cell invasion & macropinocytosis
The GAS6–AXL signaling pathway triggers actin remodeling that drives membrane ruffling, macropinocytosis, and cancer-cell invasion (2021). PNAS 118(28): e2024596118. DOI: 10.1073/pnas.2024596118
WDFY2 restrains matrix metalloproteinase secretion and cell invasion by controlling VAMP3-dependent recycling (2019). Nature Communications 10(1): 2850. DOI: 10.1038/s41467-019-10651-y. ✉
Tumor suppression by control of matrix metalloproteinase recycling (2019). Molecular & Cellular Oncology 6(6): e1646606. DOI: 10.1080/23723556.2019.1646606. ✉
Autophagy & membrane remodeling
ATPase activity of DFCP1 controls selective autophagy (2023). Nature Communications 14(1): 4051. DOI: 10.1038/s41467-023-31547-0. ✉
ATPase-regulated autophagosome biogenesis (2024). Autophagy 20(1): 218–219. DOI: 10.1080/15548627.2023.xxxxxx. ✉
Omegasomes control formation, expansion, and closure of autophagosomes (2025). BioEssays 46(6): e2400038. DOI: 10.1002/bies.202400038. ✉
ESCRT-mediated phagophore sealing during mitophagy (2020). Autophagy 16(5): 826–841. DOI: 10.1080/15548627.2019.1659618
Membrane repair & vesicle biogenesis
ESCRT-mediated lysosome repair precedes lysophagy and promotes cell survival (2018). EMBO Journal 37(21): e99753. DOI: 10.15252/embj.201899753
Concerted ESCRT and clathrin recruitment waves define the timing and morphology of intraluminal vesicle formation (2018). Nature Communications 9(1): 2932. DOI: 10.1038/s41467-018-05345-1