Guttorm Haraldsen

Professor II
Image of Guttorm Haraldsen
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Phone +47 23071492
Mobile phone +47 92401962
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Research Interests

  • Inflammation, drug development, cytokines, tissue repair, vascular biology

Education

  • MD University of Bonn 1989
  • PhD University of Oslo 1997

Employment and Professional Experience

  • Research Director, Division of Diagnostics and Intervention, Oslo University Hospital, 2010-current
  • Research Director, Division of Pathology, Rikshospitalet University Hospital 2005-2009
  • Biobank coordinator/Senior Scientist, Rikshospitalet 2005
  • Senior Scientist, Department of Pathology, Rikshospitalet 2002-2004
  • Visiting Scientist, Novartis Research Institute, Vienna 2001-2002
  • Scientist, Inst. of Pathology, University of Oslo 2000-2002
  • Postdoctoral Fellow, Inst. of Pathology, University of Oslo
  • Postdoctoral Fellow, Dept of Pathology (head, prof. E.C. Butcher, MD), Stanford University, Stanford, CA, 1997-1998
  • Research Fellow, Inst. of Pathology (head, prof. P. Brandtzaeg, PhD), Univ. of Oslo, 1992-1997

Synopsis of scientific production

  • Total career publications: 101, Citations: 8242, H-index: 40, i10-index: 63, average citations per item: 52 (Google Scholar, Feb 2019). Number of original publications in peer-reviewed journals or peer-reviewed monographs: 74, Number of review articles and book chapters: 18.
  • Publications include papers in Nature (41.5, 1*), Immunity (21.6, 1), Gastroenterology (16.7, 1), Gut (14.7, 3), J Exp Med (12.5, 4), Hepatology (11.3, 1), Blood (10.5, 5), Trends Immunol (10.4, 3), PNAS (9.7, 1), J Invest Dermatol (7.2, 1), ATVB (6.0, 2), Am J Transplant (5.7, 1), J Immunol (5.4, 4), Am J Pathol (4.6, 6) and J. Biol. Chem (4.6, 1). *journal impact factor, number of papers

Awards and Honors

  • Director and Partner in K.G. Jebsen Inflammation Research Centre 2013-2017
  • Professor Kreyberg’s prize of Experimental Pathology 2013-2016 to Eirik Sundlisæter for his PhD Thesis (supervisor: Guttorm Haraldsen)
  • Professor Kreyberg’s prize of Experimental Pathology 2005-2008 to Dag Kristian Skovseth for his PhD Thesis (supervisor: Guttorm Haraldsen)
  • Career Investigator, Research Council of Norway 2000-2005
  • Odd Fellow Medical Award 1999, 2000, 2001

Collaborations

  • Ralph Adams, Max-Planck Institut, Münster
  • Martin Knöfler, University of Vienna
  • Kim Midwood, Oxford University
  • Tatiana Petrova, Helsinki University
  • Stefan Pflanz, Merck Research Labs (former DNAX), Palo Alto
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  • Pål Aukrust, OUS
  • Alexandre Corthay, OUS
  • Bjørn Dahlhus, OUS
  • Zlatko Dembic, Oralbiologi, UiO
  • Jon Florholmen, UNN
  • Pål-Dag Line, OUS
  • Kjetil Taskén, Bioteknologisenteret
  • Morten Vatn, OUS/Ahus

Publications

  • Christopoulos, Panagiotis; Gjølberg, Torleif Tollefsrud; Krüger, Stig; Haraldsen, Guttorm; Andersen, Jan Terje & Sundlisæter, Eirik (2021). Targeting the Notch Signaling Pathway in Chronic Inflammatory Diseases. Frontiers in Immunology. ISSN 1664-3224. 12:668207, p. 1–22. doi: 10.3389/fimmu.2021.668207. Full text in Research Archive
  • Fjær, Roar; Marciniak, Katarzyna; Sundnes, Olav; Hjorthaug, Hanne; Sheng, Ying & Hammarström, Clara Louise [Show all 18 contributors for this article] (2021). A novel somatic mutation in GNB2 provides new insights to the pathogenesis of Sturge-Weber syndrome. Human Molecular Genetics. ISSN 0964-6906. 30(21), p. 1919–1931. doi: 10.1093/hmg/ddab144. Full text in Research Archive
  • Lossius, Astrid Haaskjold; Sundnes, Olav; Ingham, Anna Cäcilia; Edslev, Sofie Marie; Bjørnholt, Jørgen Vildershøj & Lilje, Berit [Show all 12 contributors for this article] (2021). Shifts in the Skin Microbiota after UVB Treatment in Adult Atopic Dermatitis. Dermatology. ISSN 1018-8665. p. 1–12. doi: 10.1159/000515236. Full text in Research Archive
  • Hol, Johanna; Haraldsen, Guttorm; Falk, Knut & Edelmann, Reidunn Jetne (2021). Endothelial cells in emerging viral infections. Frontiers in Cardiovascular Medicine. ISSN 2297-055X. 8, p. 1–23. doi: 10.3389/fcvm.2021.619690. Full text in Research Archive
  • Li, Gaoyang; Kolan, Shrikant; Guo, Shuai; Marciniak, Katarzyna; Kolan, Pratibha Shrikant & Malachin, Giulia [Show all 9 contributors for this article] (2021). Activated, Pro-Inflammatory Th1, Th17, and Memory CD4+ T Cells and B Cells Are Involved in Delayed-Type Hypersensitivity Arthritis (DTHA) Inflammation and Paw Swelling in Mice. Frontiers in Immunology. ISSN 1664-3224. 12, p. 1–15. doi: 10.3389/fimmu.2021.689057. Full text in Research Archive
  • Wik, Jonas Aakre; Phung, Danh; Kolan, Shrikant; Haraldsen, Guttorm; Skålhegg, Bjørn Steen & Hol Fosse, Johanna (2021). Inflammatory activation of endothelial cells increases glycolysis and oxygen consumption despite inhibiting cell proliferation. FEBS Open Bio. ISSN 2211-5463. 11(6), p. 1719–1730. doi: 10.1002/2211-5463.13174. Full text in Research Archive
  • Sundnes, Olav; Ottestad, William Arne; Schjalm, Camilla; Lundbäck, Peter; La Cour Poulsen, Lars & Mollnes, Tom Eirik [Show all 8 contributors for this article] (2021). Rapid systemic surge of IL-33 after severe human trauma: a prospective observational study. Molecular medicine (Cambridge, Mass. Print). ISSN 1076-1551. 27:29, p. 1–10. doi: 10.1186/s10020-021-00288-1. Full text in Research Archive
  • Gatti, Francesca; Mia, Sobuj; Hammarström, Clara Louise; Frerker, Nadine; Fosby, Bjarte & Wang, Junbai [Show all 11 contributors for this article] (2021). Nuclear IL-33 restrains the early conversion of fibroblasts to an extracellular matrix-secreting phenotype. Scientific Reports. ISSN 2045-2322. 11:108(1), p. 1–13. doi: 10.1038/s41598-020-80509-5. Full text in Research Archive
  • Lossius, Astrid Haaskjold; Berents, Teresa Løvold; Sætre, Frank Ove; Nilsen, Hogne Røed; Bradley, Maria & Asad, Samina [Show all 9 contributors for this article] (2020). Early transcriptional changes after UVB treatment in atopic dermatitis includes inverse regulation of IL‐36γ and IL‐37. Experimental Dermatology. ISSN 0906-6705. 30(2), p. 249–261. doi: 10.1111/exd.14217. Full text in Research Archive
  • Lu, Yuning; Basatemur, Gemma; Scott, Ian C.; Chiarugi, Davide; Clement, Marc & Harrison, James [Show all 19 contributors for this article] (2020). Interleukin-33 Signaling Controls the Development of Iron-Recycling Macrophages. Immunity. ISSN 1074-7613. 52(5), p. 782–793.e5. doi: 10.1016/j.immuni.2020.03.006.
  • Wik, Jonas Aakre; Lundbäck, Peter; La Cour Poulsen, Lars; Haraldsen, Guttorm; Skålhegg, Bjørn Steen & Hol, Johanna (2020). 3PO inhibits inflammatory NFκB and stress-activated kinase signaling in primary human endothelial cells independently of its target PFKFB3. PLOS ONE. ISSN 1932-6203. 15:e0229395(3), p. 1–18. doi: 10.1371/journal.pone.0229395. Full text in Research Archive
  • Pihlstrøm, Hege; Ueland, Thor; Michelsen, Annika; Aukrust, Pål; Gatti, Francesca & Hammarström, Clara Louise [Show all 15 contributors for this article] (2020). Exploring the potential effect of paricalcitol on markers of inflammation in de novo renal transplant recipients. PLOS ONE. ISSN 1932-6203. 15:e0243759(12), p. 1–14. doi: 10.1371/journal.pone.0243759. Full text in Research Archive
  • Pietka, Wojciech; Sundnes, Olav; Hammarström, Clara Louise; Zucknick, Manuela; Khnykin, Denis & Haraldsen, Guttorm (2020). Lack of interleukin-33 and its receptor does not prevent calcipotriol-induced atopic dermatitis-like inflammation in mice. Scientific Reports. ISSN 2045-2322. 10:6451, p. 1–8. doi: 10.1038/s41598-020-63410-z. Full text in Research Archive
  • Ottestad, William Arne; Rognes, Ingrid Nygren; Skaga, Erlend; Frisvoll, Cassandra; Haraldsen, Guttorm & Eken, Torsten [Show all 7 contributors for this article] (2019). HMGB1 concentration measurements in trauma patients: assessment of pre-analytical conditions and sample material. Molecular medicine (Cambridge, Mass. Print). ISSN 1076-1551. 26:5(1), p. 1–8. doi: 10.1186/s10020-019-0131-0. Full text in Research Archive
  • Pietka, Wojciech; Khnykin, Denis; Bertelsen, Vibeke; Lossius, Astrid Haaskjold; Stav-Noraas, Tor Espen & Hol, Johanna [Show all 9 contributors for this article] (2018). Hypo-osmotic stress drives IL-33 production in human keratinocytes - An epidermal homeostatic response. Journal of Investigative Dermatology. ISSN 0022-202X. 139(1), p. 81–90. doi: 10.1016/j.jid.2018.07.023. Full text in Research Archive
  • La Cour Poulsen, Lars; Edelmann, Reidunn Jetne; Krüger, Stig; Diéguez-Hurtado, Rodrigo; Shah, Akshay & Stav-Noraas, Tor Espen [Show all 22 contributors for this article] (2018). Inhibition of endothelial NOTCH1 signaling attenuates inflammation by reducing cytokine-mediated histone acetylation at inflammatory enhancers . Arteriosclerosis, Thrombosis and Vascular Biology. ISSN 1079-5642. 38(4), p. 854–869. doi: 10.1161/ATVBAHA.117.310388. Full text in Research Archive
  • Stav-Noraas, Tor Espen; Edelmann, Reidunn Jetne; La Cour Poulsen, Lars; Sundnes, Olav; Phung, Danh & Kuchler, Axel Matthias [Show all 11 contributors for this article] (2017). Endothelial IL-33 expression is augmented by adenoviral activation of the DNA damage machinery. Journal of Immunology. ISSN 0022-1767. 198(8), p. 3318–3325. doi: 10.4049/jimmunol.1600054. Full text in Research Archive
  • Pihlstrøm, Hege; Gatti, Francesca; Hammarström, Clara Louise; Eide, Ivar Anders; Kasprzycka, Monika & Wang, Junbai [Show all 13 contributors for this article] (2017). Early introduction of oral paricalcitol in renal transplant recipients. An open-label randomized study. Transplant International. ISSN 0934-0874. 30(8), p. 827–840. doi: 10.1111/tri.12973.
  • Pihlstrøm, Hege; Mjøen, Geir; Mucha, S; Haraldsen, Guttorm; Franke, A & Jardine, A [Show all 9 contributors for this article] (2016). Single Nucleotide Polymorphisms and Long-Term Clinical Outcome in Renal Transplant Patients: A Validation Study. American Journal of Transplantation. ISSN 1600-6135. 17(2), p. 528–533. doi: 10.1111/ajt.13995.
  • Cantelmo, Anna Rita; Conradi, Lena-Christin; Brajic, Aleksandra; Goveia, Jermaina; Kalucka, Joanna & Pircher, Andreas [Show all 34 contributors for this article] (2016). Inhibition of the Glycolytic Activator PFKFB3 in Endothelium Induces Tumor Vessel Normalization, Impairs Metastasis, and Improves Chemotherapy. Cancer Cell. ISSN 1535-6108. 30(6), p. 968–985. doi: 10.1016/j.ccell.2016.10.006.
  • Lorvik, Kristina Berg; Hammarström, Clara Louise; Fauskanger, Marte; Haabeth, Ole Audun; Zangani, Michael M & Haraldsen, Guttorm [Show all 8 contributors for this article] (2016). Adoptive transfer of tumor-specific Th2 cells eradicates tumors by triggering an in situ inflammatory immune response. Cancer Research. ISSN 0008-5472. 76(23), p. 6864–6876. doi: 10.1158/0008-5472.CAN-16-1219.
  • Gundersen, Mona Dixon; Goll, Rasmus; Hol, Johanna; Olsen, Trine; Rismo, Renathe & Sørbye, Sveinung Wergeland [Show all 9 contributors for this article] (2016). Loss of interleukin 33 expression in colonic crypts - a potential marker for disease remission in ulcerative colitis. Scientific Reports. ISSN 2045-2322. 6. doi: 10.1038/srep35403. Full text in Research Archive
  • Kasprzycka, Monika; Hammarström, Clara Louise & Haraldsen, Guttorm (2015). Tenascins in fibrotic disorders-from bench to bedside. Cell Adhesion & Migration. ISSN 1933-6918. 9(1-2), p. 83–89. doi: 10.4161/19336918.2014.994901.
  • Schrumpf, Elisabeth; Tan, Corey; Karlsen, Tom Hemming; Sponheim, Jon; Björkström, Niklas K. & Sundnes, Olav [Show all 16 contributors for this article] (2015). The biliary epithelium presents antigens to and activates natural killer T cells. Hepatology. ISSN 0270-9139. 62(4), p. 1249–1259. doi: 10.1002/hep.27840.
  • Sundnes, Olav; Pietka, Wojciech; Loos, Tamara; Sponheim, Jon; Rankin, Andrew L. & Pflanz, Stefan [Show all 11 contributors for this article] (2015). Epidermal expression and regulation of interleukin-33 during homeostasis and inflammation: Strong species differences. Journal of Investigative Dermatology. ISSN 0022-202X. 135(7), p. 1771–1780. doi: 10.1038/jid.2015.85.
  • Øynebråten, Inger; Barois, Nicolas; Bergeland, Trygve; Kuchler, Axel Matthias; Bakke, Oddmund & Haraldsen, Guttorm (2015). Oligomerized, filamentous surface presentation of RANTES/CCL5 on vascular endothelial cells. Scientific Reports. ISSN 2045-2322. 5:9261. doi: 10.1038/srep09261. Full text in Research Archive
  • Tveita, Anders; Schjesvold, Fredrik Hellem; Sundnes, Olav; Haabeth, Ole Audun; Haraldsen, Guttorm & Bogen, Bjarne (2014). Indirect CD4+ T-cell-mediated elimination of MHC II(NEG) tumor cells is spatiallyrestricted and fails to prevent escape of antigen-negative cells. European Journal of Immunology. ISSN 0014-2980. 44(9), p. 2625–2637. doi: 10.1002/eji.201444659.
  • Skårn, Magne Nordang; Noordhuis, Paul; Wang, Mengyu; Veuger, Maria Johanna; Kresse, Stine Henrichson & Egeland, Eivind Valen [Show all 15 contributors for this article] (2014). Generation and characterization of an immortalized human mesenchymal stromal cell line. Stem Cells and Development. ISSN 1547-3287. 23(19), p. 2377–2389. doi: 10.1089/scd.2013.0599.
  • Pandya, Abhilash D.; Leergaard, Trygve Brauns; Dissen, Erik; Haraldsen, Guttorm & Spurkland, Anne (2014). Expression of the T cell-specific adapter protein in human tissues. Scandinavian Journal of Immunology. ISSN 0300-9475. 80(3), p. 169–179. doi: 10.1111/sji.12199.
  • Pollheimer, Jürgen; Bodin, Johanna; Sundnes, Olav; Bekkeheien, Reidunn C; Skånland, Sigrid Strand & Sponheim, Jon [Show all 16 contributors for this article] (2013). Interleukin-33 drives a proinflammatory endothelial activation that selectively targets nonquiescent cells. Arteriosclerosis, Thrombosis and Vascular Biology. ISSN 1079-5642. 33(2), p. e47–e55. doi: 10.1161/ATVBAHA.112.253427.
  • Sundlisæter, Eirik; Bekkeheien, Reidunn C; Hol, Johanna; Sponheim, Jon; Kuchler, Axel Matthias & Weiss, Miriam [Show all 10 contributors for this article] (2012). The Alarmin IL-33 Is a Notch Target in Quiescent Endothelial Cells. American Journal of Pathology. ISSN 0002-9440. 181(3), p. 1099–1111. doi: 10.1016/j.ajpath.2012.06.003.
  • Hol, Johanna; Otterdal, Kari; Breland, Unni Mathilde; Stang, Espen; Pedersen, Turid Margrethe & Hagelsteen, Kathrine [Show all 11 contributors for this article] (2012). Statins Affect the Presentation of Endothelial Chemokines by Targeting to Multivesicular Bodies. PLOS ONE. ISSN 1932-6203. 7(7). doi: 10.1371/journal.pone.0040673.
  • Pollheimer, Jürgen; Haslinger, Peter; Fock, Valerie; Prast, Johanna; Saleh, Leila & Biadasiewicz, Katarzyna [Show all 11 contributors for this article] (2011). Endostatin Suppresses IGF-II-Mediated Signaling and Invasion of Human Extravillous Trophoblasts. Endocrinology. ISSN 0013-7227. 152(11), p. 4431–4442. doi: 10.1210/en.2011-1196.
  • Haabeth, Ole Audun; Lorvik, Kristina Berg; Hammarstrøm, Clara Louise; Donaldson, Ian Matthew; Haraldsen, Guttorm & Bogen, Bjarne [Show all 7 contributors for this article] (2011). Inflammation driven by tumour-specific Th1 cells protects against B-cell cancer. Nature Communications. ISSN 2041-1723. 2. doi: 10.1038/ncomms1239.
  • Norrmén, C.; Vandevelde, Wouter; Ny, Annelii; Saharinen, Pipsa; Gentile, M. & Haraldsen, Guttorm [Show all 11 contributors for this article] (2010). Liprin beta 1 is highly expressed in lymphatic vasculature and is important for lymphatic vessel integrity. Blood. ISSN 0006-4971. 115(4), p. 906–909. doi: 10.1182/blood-2009-03-212274.
  • Sponheim, Jon; Pollheimer, Jürgen; Olsen, Trine; Balogh, Eva Johanna; Hammarström, Clara & Loos, Tamara [Show all 12 contributors for this article] (2010). Inflammatory Bowel Disease-Associated Interleukin-33 Is Preferentially Expressed in Ulceration-Associated Myofibroblasts. American Journal of Pathology. ISSN 0002-9440. 177(6), p. 2804–2815. doi: 10.2353/ajpath.2010.100378.
  • Mikalsen, Bjørg; Fosby, Bjarte; Wang, Jacob Edward; Hammarstrom, C; Brundvold, Hilde & Lundström, Marlene [Show all 10 contributors for this article] (2010). Genome-Wide Transcription Profile of Endothelial Cells After Cardiac Transplantation in the Rat. American Journal of Transplantation. ISSN 1600-6135. 10(7), p. 1534–1544. doi: 10.1111/j.1600-6143.2010.03157.x.
  • Hol, Johanna; Wilhelmsen, Linn & Haraldsen, Guttorm (2010). The murine IL-8 homologues KC, MIP-2, and LIX are found in endothelial cytoplasmic granules but not in Weibel-Palade bodies. Journal of Leukocyte Biology. ISSN 0741-5400. 87(3), p. 501–508. doi: 10.1189/jlb.0809532.
  • Haraldsen, Guttorm; Balogh, Eva Johanna; Pollheimer, Jürgen; Sponheim, Jon & Kuchler, Axel Matthias (2009). Interleukin-33-cytokine of dual function or novel alarmin? Trends in immunology. ISSN 1471-4906. 30(5), p. 227–233. doi: 10.1016/j.it.2009.03.003.
  • Hol, Johanna; Kuchler, Axel Matthias; Dalhus, Bjørn; Johansen, Finn Eirik; Haraldsen, Guttorm & Øynebråten, Inger (2009). Molecular Requirements for Sorting of the Chemokine Interleukin-8/CXCL8 to Endothelial Weibel-Palade Bodies. Journal of Biological Chemistry. ISSN 0021-9258. 284(35), p. 23532–23539. doi: 10.1074/jbc.M900874200.
  • Etokebe, Godfrey; Kuchler, Axel Matthias; Haraldsen, Guttorm; Landin, Maria Augusta Dos S Silva; Osmundsen, Harald & Dembic, Zlatko (2009). Family-with-sequence-similarity-46, member A (Fam46a) gene is expressed in developing tooth buds. Archives of Oral Biology. ISSN 0003-9969. 54(11), p. 1002–1007. doi: 10.1016/j.archoralbio.2009.08.005.
  • Sæthre, Marit; Schneider, MKJ; Lambris, JD; Magotti, P; Haraldsen, Guttorm & Seebach, JD [Show all 7 contributors for this article] (2008). Cytokine secretion depends on Gal alpha(1,3)Gal expression in a pig-to-human whole blood model. Journal of Immunology. ISSN 0022-1767. 180, p. 6346–6353.
  • Kuchler, Axel Matthias; Pollheimer, Jürgen; Balogh, Eva Johanna; Sponheim, Jon; Manley, Linda & Sørensen, Dag Reidar [Show all 9 contributors for this article] (2008). Nuclear interleukin-33 is generally expressed in resting endothelium but rapidly lost upon angiogenic or proinflammatory activation. American Journal of Pathology. ISSN 0002-9440. 173, p. 1229–1242. doi: 10.2353/ajpath.2008.080014.
  • Breland, Unni Mathilde; Halvorsen, Bente ; Hol, Johanna; Øie, Erik; Paulsson-Berne, G & Yndestad, Arne [Show all 17 contributors for this article] (2008). A potential role of the CXC chemokine GRO alpha in atherosclerosis and plaque destabilization - Downregulatory effects of statins. Arteriosclerosis, Thrombosis and Vascular Biology. ISSN 1079-5642. 28. doi: 10.1161/ATVBAHA.108.162305.
  • Skovseth, Dag Kristian; Kuchler, Axel Matthias & Haraldsen, Guttorm (2007). The HUVEC/Matrigel assay: an in vivo assay of human angiogenesis suitable for drug validation. Methods in molecular biology. ISSN 1064-3745. 360, p. 253–268.
  • Sæthre, Marit; Lea, Tor; Borgen, Merethe S.; Fiane, Arnt E.; Michaelsen, Terje Einar & Thorsby, Erik [Show all 8 contributors for this article] (2006). Human complement-activating immunoglobulin (Ig)G3 antibodies are essential for porcine endothelial cell activation. Xenotransplantation. ISSN 0908-665X. 13(3), p. 215–223. doi: 10.1111/j.1399-3089.2006.00289x.
  • Bækkevold, Espen Sønderaal; Wurbel, M-A; Kivisäkk, P; Wain, CM; Power, CA & Haraldsen, Guttorm [Show all 7 contributors for this article] (2005). A role for CCR4 in development of mature circulating cutaneous T helper memory cell populations. Journal of Experimental Medicine (JEM). ISSN 0022-1007. 201, p. 1045–1051.
  • Qiao, Shuo-Wang; Piper, J; Haraldsen, Guttorm; Øynebråten, Inger; Fleckenstein, Burkhard & Molberg, Øyvind [Show all 8 contributors for this article] (2005). Tissue transglutaminase-mediated formation and cleavage of histamine-gliadin complexes: biological effects and implications for celiac disease. Journal of Immunology. ISSN 0022-1767. 174, p. 1657–1663.
  • Skovseth, Dag Kristian; Veuger, Maria Johanna; Sørensen, Dag Reidar; De Angelis, Paula & Haraldsen, Guttorm (2005). Endostatin dramatically inhibits endothelial cell migration, vascular morphogenesis and perivascular cell recruitment in vivo. Blood. ISSN 0006-4971. 105, p. 1044–1051.
  • Corthay, Alexandre; Skovseth, Dag Kristian; Lundin, Katrin; Røsjø, Egil; Omholt, Hilde & Hofgaard, Peter Olaf [Show all 8 contributors for this article] (2005). Primary antitumor immune response mediated by CD4+ T cells. Immunity. ISSN 1074-7613. 22, p. 371–383.
  • Carlsen, Hege Synnøve; Haraldsen, Guttorm; Brandtzæg, Per & Bækkevold, Espen Sønderaal (2005). Disparate lymphoid chemokine expression in mice and men: no evidence of CCL21 synthesis by human high endothelial venules. Blood. ISSN 0006-4971. 106, p. 444–446.
  • Øynebråten, Inger; Barois, Nicolas; Hagelsteen, Kathrine; Johansen, Finn Eirik; Bakke, Oddmund & Haraldsen, Guttorm (2005). Characterization of a novel chemokine-containing storage granule in endothelial cells: evidence for preferential exocytosis mediated by protein kinase A and diacylglycerol. Journal of Immunology. ISSN 0022-1767. 175(8), p. 5358–5369.
  • Øynebråten, Inger; Barois, Nicolas; Hagelsteen, Kathrine; Johansen, Finn Eirik; Bakke, Oddmund & Haraldsen, Guttorm (2005). Characterization of a novel chemokine-containing storage granule in endothelial cells: evidence for preferential exocytosis mediated by protein kinase A and diacylglycerol. Journal of Immunology. ISSN 0022-1767. 175(8), p. 5358–5369.
  • Øynebråten, Inger; Oynebraten, Inger; Bakke, Oddmund; Brandtzæg, Per; Johansen, Finn Erik & Haraldsen, Guttorm (2004). Rapid chemokine secretion from endothelial cells originates from 2 distinct compartments. Blood. ISSN 0006-4971. 104(2), p. 314–320.
  • Lacorre, D-A; Bækkevold, Espen S.; Garrido, I; Brandtzæg, Per; Haraldsen, Guttorm & Amalric, F [Show all 7 contributors for this article] (2004). Plasticity of endothelial cells: rapid dedifferentiation of freshly isolated high endothelial venule endothelial cells outside the lymphoid tissue microenvironment. Blood. ISSN 0006-4971. 103, p. 4164–4172.
  • Bækkevold, Espen S.; Roussigné, M; Yamanaka, Takeshi; Johansen, Finn Eirik; Jahnsen, Frode Lars & Amalric, F [Show all 10 contributors for this article] (2003). Molecular characterization of NF-HEV, a nuclear factor preferentially expressed in human high endothelial venules. American Journal of Pathology. ISSN 0002-9440. 163, p. 69–79.
  • Chi, J-T; Chang, HY; Haraldsen, Guttorm; Jahnsen, Frode Lars; Troyanskaya, OG & Chang, DS [Show all 11 contributors for this article] (2003). Endothelial cell diversity revealed by global expression profiling. Proceedings of the National Academy of Sciences of the United States of America. ISSN 0027-8424. 100, p. 10623–10628.
  • Carlsen, Hege Synnøve; Bækkevold, Espen S.; Johansen, Finn Eirik; Haraldsen, Guttorm & Brandtzæg, Per (2002). B cell attracting chemokine 1 (CXCL13) and its receptor CXCR5 are expressed in normal and aberrant gut associated lymphoid tissue. Gut. ISSN 0017-5749. 51, p. 364–371.
  • Farstad, Inger Nina; Malavasi, F.; Haraldsen, Guttorm; Huitfeldt, Henrik & Brandtzæg, Per (2002). CD38 is a marker of human lacteals. Virchows Archiv. ISSN 0945-6317. 441, p. 605–613.
  • Skovseth, Dag Kristian; Yamamoto, Takeshi; Brandtzæg, Per; Butcher, Eugene & Haraldsen, Guttorm (2002). Vascular morphogenesis and differentiation following adoptive transfer of human endothelial cells to immunodeficient mice. American Journal of Pathology. ISSN 0002-9440. 160, p. 1629–1637.
  • Skovseth, Dag Kristian; Sørensen, Dag R. & Haraldsen, Guttorm (2002). Vascular morphogenesis and differentiation following adoptive transfer of human endothelial cells to immunodeficient mice. American Journal of Pathology. ISSN 0002-9440.
  • Sæthre, Marit; Sølvik, Una Ørvim; Haraldsen, Guttorm; Fiane, Arnt E.; Boretti, Eva & Thorsby, Erik [Show all 8 contributors for this article] (2002). Human serum-induced porcine endothelial cell E-selectin expression is associated with IgG3 and IgM anti-Gal antibodies. Xenotransplantation. ISSN 0908-665X. 9, p. 350–358.
  • Bækkevold, Espen S.; Yamamoto, Takeshi; Palframan, R.T.; Carlsen, Hege Synnøve; Reinholt, Finn P. & Andrian, U. H. von [Show all 8 contributors for this article] (2001). The CCR7 ligand ELC (CCL19) is transcytosed in high endothelial venules and mediates T cell recruitment. Journal of Experimental Medicine (JEM). ISSN 0022-1007. 193(9), p. 1105–1112.
  • Sølvik, Una Ørvim; Haraldsen, Guttorm; Fiane, Arnt E.; Boretti, Eva; Lambris, J.D. & Fung, M. [Show all 8 contributors for this article] (2001). Human serum-induced E-selectin expression on porcine aortic endothelial cells in vitro is totally complement mediated. Transplantation. ISSN 0041-1337. 72, p. 1967–1973.
  • Sølvik, Una Ørvim; Haraldsen, Guttorm; Fiane, Arnt E.; Boretti, Eva; Thorsby, Erik & Mollnes, Tom Eirik (2001). C1-inhibitor attenuates human serum induced E-selectin expression of pig aortic endothelial cells. Transplantation Proceedings. ISSN 0041-1345. 33, p. 789–790.
  • Sølvik, Una Ørvim; Haraldsen, Guttorm; Fiane, Arnt E.; Boretti, Eva; Lambris, J.D. & Fung, M. [Show all 8 contributors for this article] (2001). Human serum-induced E-selectin expression on porcine aortic endothelial cells in vitro is totally complement mediated. Transplantation. ISSN 0041-1337. 72, p. 1967–1973.
  • Sølvik, Una Ørvim; Haraldsen, Guttorm; Fiane, Arnt E.; Boretti, Eva; Thorsby, Erik & Mollnes, Tom Eirik (2001). C1 inhibitor attenuates human serum induced E-selectin expression of pig aortic endothelial cells. Transplantation Proceedings. ISSN 0041-1345. p. 789–790.
  • Sølvik, Una Ørvim; Haraldsen, Guttorm; Fiane, Arnt E.; Boretti, Eva; Lambris, J.D. & Fung, M. [Show all 8 contributors for this article] (2001). Human serum-induced E-selectin expression on porcine aortic endothelial cells in vitro is totally complement mediated. Transplantation. ISSN 0041-1337.
  • Kunkel, Eric; Campbell, James; Haraldsen, Guttorm; Pan, Junliang; Boisvert, Judie & Roberts, Arthur [Show all 16 contributors for this article] (2000). Lymphocyte CC chemokine receptor 9 and epithelial thymus-expressed chemokine (TECK) expression distinguish the small intestinal immune compartment: Epithelial expression of tissue-specific chemokines as an organizing principle in regional immunity. Journal of Experimental Medicine (JEM). ISSN 0022-1007. p. 761–767.
  • Sindre, Hilde; Haraldsen, Guttorm; Beck, Solveig; Hestad, Kjetil; Kvale, Dag & Brandtzæg, Per [Show all 8 contributors for this article] (2000). Human intestinal endothelium shows high susceptibility to cytomegalovirus and altered expression of adhesion molecules after infection. Scandinavian Journal of Immunology. ISSN 0300-9475. 51, p. 354–360.
  • Sindre, Hilde; Haraldsen, Guttorm; Beck, Solveig; Hestad, Kjetil; Kvale, Dag & Brandtzæg, Per [Show all 8 contributors for this article] (2000). Human intestinal endothelium shows high susceptibility to cytomegalovirus and altered expression of adhesion molecules after infection. Scandinavian Journal of Immunology. ISSN 0300-9475. 51, p. 354–360.

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  • Haabeth, Ole Audun; Lorvik, Kristina Berg; Hammarström, Clara Louise; Donaldson, Ian M; Haraldsen, Guttorm & Bogen, Bjarne [Show all 7 contributors for this article] (2016). Kreft-spesifikke betennelsesreaksjoner kan beskytte mot kreft. BestPractice. Onkologi Hematologi. February.
  • Schjesvold, Fredrik Hellem; Tveita, Anders; Sundnes, Olav; Haraldsen, Guttorm & Bogen, Bjarne (2013). CD4+T cell-mediated protection against tumors: no bystander killing. Journal of Immunology. ISSN 0022-1767. 190.
  • Haraldsen, Guttorm (2013). Interleukin-33 drives a proinflammatory endothelial activation that selectively targets non-quiescent cells. The FASEB Journal. ISSN 0892-6638. 27.
  • Sundnes, Olav; Khnykin, Denis & Haraldsen, Guttorm (2013). Cellular expression of the alarmin IL-33 in acute skin inflammation. Journal of Investigative Dermatology. ISSN 0022-202X. 133, p. S52–S52.
  • Haraldsen, Guttorm; Jetne, Reidunn; Hol, Johanna; Sponheim, Jon; Kuchler, Axel Matthias & Kasprzycka, Monika [Show all 7 contributors for this article] (2012). The Alarmin Interleukin-33 is a Notch Target in Quiescent Endothelial Cells. Journal of Immunology. ISSN 0022-1767. 188.
  • Haabeth, Ole Audun; Lorvik, Kristina Berg; Hammarström, Clara; Donaldson, Ian Matthew; Haraldsen, Guttorm & Bogen, Bjarne [Show all 7 contributors for this article] (2011). Cancer Immunosurveillance by CD4(+) T Cells. Scandinavian Journal of Immunology. ISSN 0300-9475. 73(6), p. 603–603.
  • Haabeth, Ole Audun; Lorvik, Kristina Berg; Hammarstrom, C; Donaldson, Ian Matthew; Haraldsen, Guttorm & Bogen, Bjarne [Show all 7 contributors for this article] (2011). A cancer-protective role of inflammation. Cytokine. ISSN 1043-4666. 56(1), p. 101–101. doi: 10.1016/j.cyto.2011.07.392.
  • Sundlisæter, Eirik; Bekkeheien, Reidunn C; Hol, Johanna; Sponheim, Jon; Kuchler, Axel Matthias & Kasprzycka, Monika [Show all 7 contributors for this article] (2011). The Putative Alarmin IL-33 is Induced and Maintained in Resting Endothelial Cells by Notch Ligand DLL4. Scandinavian Journal of Immunology. ISSN 0300-9475. 73(4), p. 366–366.
  • Haabeth, Ole Audun; Lorvik, Kristina Berg; Hammarström, Clara; Donaldson, Ian Matthew; Haraldsen, Guttorm & Bogen, Bjarne [Show all 7 contributors for this article] (2011). Inflammation Driven by Tumor-Specific Th1 Cells Protects against B-Cell Cancer. Scandinavian Journal of Immunology. ISSN 0300-9475. 73(4), p. 384–384.
  • Sponheim, Jon; Pollheimer, Jürgen; Olsen, Trine; Balogh, Johanna; Hammarström, Clara & Loos, Tamara [Show all 12 contributors for this article] (2010). Inflammatory bowel disease-associated interleukin-33 is preferentially expressed in ulceration-associated myofibroblasts. Wound Repair and Regeneration. ISSN 1067-1927. 18(6), p. A94–A94.
  • Hol, Johanna; Kuchler, Axel Matthias; Johansen, Finn Eirik; Haraldsen, Guttorm & Øynebråten, Inger (2008). Molecular requirements for sorting of IL-8/CXCL8 to endothelial Weibel Palade bodies. Scandinavian Journal of Immunology. ISSN 0300-9475. 68, p. 228–229.
  • Mikalsen, Bjørg; Lundström, Marlene; Fosby, Bjarte; Hammarstrom, C; Bjaerke, H & Wang, J [Show all 10 contributors for this article] (2008). Genome-wide transcription profiles of endothelial cells during cardiac allograft rejection. Scandinavian Journal of Immunology. ISSN 0300-9475. 68, p. 220–221.
  • Josefsen, Dag; Kuechler, A; Wang, Mari; Haraldsen, Guttorm & Kvalheim, Gunnar (2008). Human bone marrow mononuclear cells, CD34+cells and CD133+cells do not form vascular structures in vivo. Bone Marrow Transplantation. ISSN 0268-3369. 41, p. S130–S130.
  • Westgaard, Arne; Carlsen, Hege Synnøve; Bækkevold, Espen S.; Haraldsen, Guttorm; Bergan, Anstein Bjørnar & Brandtzæg, Per (2002). "B-cell attracting chemokine 1" (CXCL13): Mulig patogenetisk rolle i inflammatorisk tarmsykdom?
  • Sæthre, Marit; Sølvik, Una Ørvim; Haraldsen, Guttorm; Fiane, Arnt E.; Boretti, Eva & Thorsby, Erik [Show all 8 contributors for this article] (2001). Human serum-induced porcine endothelial cell E-selectin expression is associated with IgG3 anti-Gal antibodies.
  • Bækkevold, Espen S.; Yamamoto, Takeshi; Palframan, R.T.; Carlsen, Hege Synnøve; Reinholt, Finn P. & Andrian, U. H. von [Show all 8 contributors for this article] (2001). The CCR7-ligand ELC (CCL19) is transcytosed in high endothelial venules and mediates T cell recruitment.
  • Sølvik, Una Ørvim; Haraldsen, Guttorm; Fiane, Arnt E.; Boretti, Eva; Lambris, J.D. & Fung, M. [Show all 8 contributors for this article] (2001). Human serum-induced E-selectin expression on porcine aortic endothelial cells is totally complement mediated: Evidence for a role of complement in delayed xenograft rejection.
  • Sølvik, Una Ørvim; Haraldsen, Guttorm; Fiane, Arnt E.; Boretti, Eva; Lambris, J.D. & Fung, M. [Show all 8 contributors for this article] (2001). Human serum-induced E-selectin expression on porcine aortic endothelial cells is totally complement mediated: evidence for a role of complement in delayed xenograft rejection.
  • Sæthre, Marit; Sølvik, Una Ørvim; Haraldsen, Guttorm; Fiane, Arnt E.; Boretti, Eva & Thorsby, Erik [Show all 8 contributors for this article] (2001). Human serum-induced porcine endothelial cell E-selectin expression is associated with Ig3 anti-gal antibodies.
  • Bækkevold, Espen S.; Yamamoto, Takeshi; Carlsen, Hege Synnøve; Brandtzæg, Per & Haraldsen, Guttorm (2001). Transcytosis of the CC chemokine ELC/CCL19 in human high endothelial venules.
  • Sæthre, Marit; Sølvik, Una Ørvim; Haraldsen, Guttorm; Fiane, Arnt E.; Boretti, Eva & Thorsby, Erik [Show all 8 contributors for this article] (2001). Human serum-induced porcine endothelial cell E-selectin expression is associated with IgG3 anti-Gal antibodies.
  • Sæthre, Marit; Sølvik, Una Ørvim; Haraldsen, Guttorm; Fiane, Arnt E.; Boretti, Eva & Thorsby, Erik [Show all 8 contributors for this article] (2001). Human serum-induced porcine endothelial cell E-selectin expression is associated with IgG3 anti-Gal antibodies.
  • Sølvik, Una Ørvim; Haraldsen, Guttorm; Fiane, Arnt E.; Boretti, Eva; Lambris, J.D. & Fung, M. [Show all 8 contributors for this article] (2001). Human serum-induced E-selectin expression on porcine aortic endothelial cells is totally complement mediated: Evidence for a role of complement in delayed xenograft rejection.
  • Sølvik, Una Ørvim; Haraldsen, Guttorm; Fiane, Arnt E.; Boretti, Eva; Lambris, J.D. & Thorsby, Erik [Show all 7 contributors for this article] (2000). Complement inhibition reduces human serum induced type II activation of porcine endothelial cells.
  • Skovseth, Dag Kristian; Butcher, Eugene; Brandtzæg, Per & Haraldsen, Guttorm (2000). Capillary morpho-genesis and differentiation following adoptive transfer of human endothelial cells to immunodeficient mice.
  • Sponheim, Jon; Haraldsen, Guttorm; Vatn, Morten H & Torsvik, Harald (2012). Inerleukin-33 in inflammation and wound repair : an experimental study with special reference to endothelial cells and myofibroblats. Unipub forlag. ISSN 978-82-8264-358-0. 2012(1329).
  • Mikalsen, Bjørg & Haraldsen, Guttorm (2011). Genome-wide endothelial cell activation profiles and matricellular protein expression after solid organ transplantation. Unipub forlag. ISSN 978-82-8072-558-5.
  • Hol, Johanna & Haraldsen, Guttorm (2010). Sorting, storage and secretion of neutrophil-recruiting CXC chemokines from endothelial cells. Unipub forlag. ISSN 978-82-8072-367-3.

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Published Apr. 13, 2011 2:54 PM - Last modified Feb. 28, 2019 8:26 PM