Jørgen Gravning

Associate Professor - Department of Cardiology

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Publications

  • Aimo, Alberto; Januzzi, James L.; Vergaro, Giuseppe; Clerico, Aldo; Latini, Roberto; Meessen, Jennifer; Anand, Inder S.; Cohn, Jay N.; Gravning, Jørgen A.; Ueland, Thor; Nymo, Ståle Haugset; Brunner-La Rocca, Hans-Peter; Bayes-Genis, Antoni; Lupón, Josep; de Boer, Rudolf A.; Yoshihisa, Akiomi; Takeishi, Yasuchika; Egstrup, Michael; Gustafsson, Ida; Gaggin, Hanna K.; Eggers, Kai M.; Huber, Kurt; Tentzeris, Ioannis; Ripoli, Andrea; Passino, Claudio & Emdin, Michele (2019). Revisiting the obesity paradox in heart failure: Per cent body fat as predictor of biomarkers and outcome. European Journal of Preventive Cardiology (EJPC).  ISSN 2047-4873.  s 1- 9 . doi: 10.1177/2047487319852809 Full text in Research Archive.
  • Kvisvik, Brede Alexander; Aagaard, Erika Nerdrum; Mørkrid, Lars; Røsjø, Helge; Lyngbakken, Magnus; Smedsrud, Marit Kristine; Eek, Christian; Bendz, Bjørn; Haugaa, Kristina; Edvardsen, Thor & Gravning, Jørgen A. (2019). Mechanical dispersion as a marker of left ventricular dysfunction and prognosis in stable coronary artery disease. The International Journal of Cardiovascular Imaging.  ISSN 1569-5794.  35, s 1265- 1275 . doi: 10.1007/s10554-019-01583-z Full text in Research Archive.
  • Aimo, Alberto; Januzzi, James L.; Vergaro, Giuseppe; Ripoli, Andrea; Latini, Roberto; Masson, Serge; Magnoli, Michela; Anand, Inder S.; Cohn, Jay N.; Tavazzi, Luigi; Tognoni, Gianni; Gravning, Jørgen A.; Ueland, Thor; Nymo, Ståle Haugset; Brunner-La Rocca, Hans-Peter; Bayes-Genis, Antoni; Lupón, Josep; de Boer, Rudolf A.; Yoshihisa, Akiomi; Takeishi, Yasuchika; Egstrup, Michael; Gustafsson, Ida; Gaggin, Hanna K.; Eggers, Kai M.; Huber, Kurt; Tentzeris, Ioannis; Wilson Tang, Wai Hong; Grodin, Justin L.; Passino, Claudio & Emdin, Michele (2018). High-sensitivity troponin T, NT-proBNP and glomerular filtration rate: A multimarker strategy for risk stratification in chronic heart failure. International Journal of Cardiology.  ISSN 0167-5273.  s 1- 7 . doi: 10.1016/j.ijcard.2018.10.079
  • Aimo, Alberto; Januzzi, James L.; Vergaro, Giuseppe; Ripoli, Andrea; Latini, Roberto; Masson, Serge; Magnoli, Michela; Anand, Inder S.; Cohn, Jay N.; Tavazzi, Luigi; Tognoni, Gianni; Gravning, Jørgen A.; Ueland, Thor; Nymo, Ståle Haugset; Rocca, Hans Peter Brunner-La; Genis, Antoni Bayes; Lupón, Josep; de Boer, Rudolf A.; Yoshihisa, Akiomi; Takeishi, Yasuchika; Egstrup, Michael; Gustafsson, Ida; Gaggin, Hanna K.; Eggers, Kai M.; Huber, Kurt; Tentzeris, Ioannis; Tang, Wai Hong Wilson; Grodin, Justin; Passino, Claudio & Emdin, Michele (2018). Prognostic value of high-sensitivity troponin T in chronic heart failure an individual patient data meta-analysis. Circulation.  ISSN 0009-7322.  137(3), s 286- 297 . doi: 10.1161/CIRCULATIONAHA.117.031560
  • Emdin, Michele; Aimo, Alberto; Vergaro, Giuseppe; Bayes-Genis, Antoni; Lupón, Josep; Latini, Roberto; Meessen, Jennifer; Anand, Inder S.; Cohn, Jay N.; Gravning, Jørgen A.; Gullestad, Lars; Broch, Kaspar; Ueland, Thor; Nymo, Ståle Haugset; Brunner-La Rocca, Hans-Peter; de Boer, Rudolf A.; Gaggin, Hanna K.; Ripoli, Andrea; Passino, Claudio & Januzzi, James L. (2018). sST2 predicts outcome in chronic heart failure beyond NT - proBNP and high-sensitivity troponin T. Journal of the American College of Cardiology.  ISSN 0735-1097.  72(19), s 2309- 2320 . doi: 10.1016/j.jacc.2018.08.2165
  • Kvisvik, Brede Alexander; Mørkrid, Lars; Røsjø, Helge; Småstuen, Milada C; Rowe, Alexander D.; Eek, Christian; Bendz, Bjørn; Edvardsen, Thor & Gravning, Jørgen A. (2017). Troponinas de alta sensibilidad T vs I en Sindrome Coronario Agudo: Prediccion de lesiones coronarias significativas y pronostico a largo plazo. Acta Bioquimica Clinica Latinoamericana.  ISSN 0325-2957.  51(3), s 395- 407
  • Kvisvik, Brede Alexander; Mørkrid, Lars; Røsjø, Helge; Småstuen, Milada Cvancarova; Rowe, Alexander D.; Eek, Christian; Bendz, Bjørn; Edvardsen, Thor & Gravning, Jørgen A. (2017). High-Sensitivity Troponin T vs I in Acute Coronary Syndrome: Prediction of Significant Coronary Lesions and Long-term Prognosis. Clinical Chemistry.  ISSN 0009-9147.  63(2), s 552- 562 . doi: 10.1373/clinchem.2016.261107
  • Nymo, Ståle Haugset; Aukrust, Pål; Kjekshus, John; McMurray, John J.V.; Cleland, John G.F.; Wikstrand, John; Muntendam, Pieter; Wienhues-Thelen, Ursula-Henrike; Latini, Roberto; Askevold, Erik Tandberg; Gravning, Jørgen A.; Dahl, Christen Peder; Broch, Kaspar; Yndestad, Arne; Gullestad, Lars & Ueland, Thor (2017). Limited added value of circulating inflammatory biomarkers in chronic heart failure. JACC. Heart failure.  ISSN 2213-1779.  5(4), s 256- 264 . doi: 10.1016/j.jchf.2017.01.008
  • Rutkovskiy, Arkady; Sagave, Julia Fritzi; Czibik, Gabor Tamas; Baysa, Anton; Zihlavnikova, Katarina; Hillestad, Vigdis; Dahl, Christen Peder; Fiane, Arnt E; Gullestad, Lars; Gravning, Jørgen A.; Ahmed, Muhammad Shakil; Attramadal, Håvard; Valen, Guro & Vaage, Ingvar Jarle (2017). Connective tissue growth factor and bone morphogenetic protein 2 are induced following myocardial ischemia in mice and humans. Scandinavian Journal of Clinical and Laboratory Investigation.  ISSN 0036-5513.  77(5), s 321- 331 . doi: 10.1080/00365513.2017.1318447
  • Smedsrud, Marit Kristine; Gravning, Jørgen A.; Omland, Torbjørn; Eek, Christian; Mørkrid, Lars; Skulstad, Helge; Aaberge, Lars; Bendz, Bjørn; Kjekshus, John & Edvardsen, Thor (2015). Sensitive cardiac troponins and N-terminal pro-B-type natriuretic peptide in stable coronary artery disease: correlation with left ventricular function as assessed by myocardial strain. The International Journal of Cardiovascular Imaging.  ISSN 1569-5794.  31(5), s 967- 973 . doi: 10.1007/s10554-015-0646-6
  • Gravning, Jørgen A.; Askevold, Erik Tandberg; Nymo, Ståle Haugset; Ueland, Thor; Wikstrand, John; McMurray, John J.V.; Aukrust, Pål; Gullestad, Lars & Kjekshus, John (2014). Prognostic effect of high-sensitive troponin t assessment in elderly patients with chronic heart failure results from the CORONA Trial. Circulation: Heart Failure.  ISSN 1941-3289.  7(1), s 96- 103 . doi: 10.1161/CIRCHEARTFAILURE.113.000450
  • Gravning, Jørgen A.; Ahmed, Muhammad Shakil; Qvigstad, Eirik; Krobert, Kurt Allen; Edvardsen, Thor; Moe, Ingvild Tronstad; Hagelin, Else Marie Valbjørn; Sagave, Julia Fritzi; Valen, Guro; Levy, Finn Olav; Osnes, Jan-Bjørn; Skomedal, Tor & Attramadal, Håvard (2013). Connective Tissue Growth Factor/CCN2 Attenuates beta-Adrenergic Receptor Responsiveness and Cardiotoxicity by Induction of G Protein-Coupled Receptor Kinase-5 in Cardiomyocytes. Molecular Pharmacology.  ISSN 0026-895X.  84(3), s 372- 383 . doi: 10.1124/mol.113.087312
  • Gravning, Jørgen A.; Ahmed, Muhammad Shakil; von Lueder, Thomas Gero; Edvardsen, Thor & Attramadal, Håvard (2013). CCN2/CTGF attenuates myocardial hypertrophy and cardiac dysfunction upon pressure-overload. International Journal of Cardiology.  ISSN 0167-5273.  168(3), s 2049- 2056 . doi: 10.1016/j.ijcard.2013.01.165
  • Gravning, Jørgen A.; Smedsrud, Marit Kristine; Omland, Torbjørn; Eek, Christian; Skulstad, Helge; Aaberge, Lars; Bendz, Bjørn; Kjekshus, John; Mørkrid, Lars & Edvardsen, Thor (2013). Sensitive troponin assays and N-terminal pro-B-type natriuretic peptide in acute coronary syndrome: Prediction of significant coronary lesions and long-term prognosis. American Heart Journal.  ISSN 0002-8703.  165(5), s 716- 724 . doi: 10.1016/j.ahj.2013.02.008
  • Askevold, Erik Tandberg; Nymo, Ståle Haugset; Ueland, Thor; Gravning, Jørgen A.; Wergeland, Ragnhild; Kjekshus, John; Yndestad, Arne; Cleland, JG; McMurray, JJ; Aukrust, Pål & Gullestad, Lars (2012). Soluble Glycoprotein 130 predicts Fatal Outcomes in Chronic Heart Failure: Analysis From the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA). Circulation: Heart Failure.  ISSN 1941-3289.  (6), s 91- 98 . doi: 10.1161/CIRCHEARTFAILURE.112.972653
  • Bilbija, Dusan; Gravning, Jørgen A.; Haugen, Fred; Attramadal, Håvard & Valen, Guro (2012). Protecting the heart through delivering DNA encoding for heme oxygenase-1 into skeletal muscle. Life Sciences.  ISSN 0024-3205.  91(17-18), s 828- 836 . doi: 10.1016/j.lfs.2012.08.014
  • Gravning, Jørgen A.; Ørn, Stein; Kaasbøll, Ole Jørgen; Martinov, Vladimir Nikolkaev; Manhenke, Cord A; Dickstein, Kenneth; Edvardsen, Thor; Attramadal, Håvard & Ahmed, Muhammad Shakil (2012). Myocardial Connective Tissue Growth Factor (CCN2/CTGF) Attenuates Left Ventricular Remodeling after Myocardial Infarction. PLOS ONE.  ISSN 1932-6203.  7(12) . doi: 10.1371/journal.pone.0052120 Show summary
  • von Lueder, Thomas Gero; Gravning, Jørgen A.; How, Ole-Jakob; Vinge, Leif Erik; Ahmed, Muhammad Shakil; Krobert, Kurt Allen; Levy, Finn Olav; Larsen, Terje; Smiseth, Otto A.; Aasum, Ellen & Attramadal, Håvard (2012). Cardiomyocyte-restricted inhibition of G protein-coupled receptor kinase-3 attenuates cardiac dysfunction after chronic pressure overload. American Journal of Physiology. Heart and Circulatory Physiology.  ISSN 0363-6135.  303(1), s H66- H74 . doi: 10.1152/ajpheart.00724.2011
  • Ahmed, Muhammad Shakil; Gravning, Jørgen A.; Martinov, Vladimir Nikolkaev; von Lueder, Thomas Gero; Edvardsen, Thor; Czibik, Gabor Tamas; Moe, Ingvild Tronstad; Vinge, Leif Erik; Øie, Erik; Valen, Guro & Attramadal, Håvard (2011). Mechanisms of novel cardioprotective functions of CCN2/CTGF in myocardial ischemia-reperfusion injury. American Journal of Physiology. Heart and Circulatory Physiology.  ISSN 0363-6135.  300(4), s H1291- H1302 . doi: 10.1152/ajpheart.00604.2010
  • Czibik, Gabor Tamas; Gravning, Jørgen A.; Martinov, Vladimir Nikolkaev; Ishaq, Bushra; Knudsen, Eirunn; Attramadal, Håvard & Valen, Guro (2011). Gene therapy with hypoxia-inducible factor 1 alpha in skeletal muscle is cardioprotective in vivo. Life Sciences.  ISSN 0024-3205.  88(11-12), s 543- 550 . doi: 10.1016/j.lfs.2011.01.006 Show summary
  • Bergestuen, Deidi Ann; Gravning, Jørgen Amundsen; Haugaa, Kristina; Sahakyan, LG; Aakhus, Svend; Thiis-Evensen, Espen; Øie, Erik; Aukrust, Pål; Attramadal, Håvard & Edvardsen, Thor (2010). Plasma CCN2/connective tissue growth factor is associated with right ventricular dysfunction in patients with neuroendocrine tumors. BMC Cancer.  ISSN 1471-2407.  10 . doi: 10.1186/1471-2407-10-6
  • Vinge, Leif Erik; von Lueder, Thomas Gero; Aasum, E; Qvigstad, Eirik; Gravning, Jørgen Amundsen; How, OJ; Edvardsen, Thor; Bjornerheim, Reidar; Ahmed, Muhammad Shakil; Mikkelsen, Birthe Viftrup; Oie, E; Attramadal, T.; Skomedal, Tor; Smiseth, Otto A.; Koch, WJ; Larsen, TS & Attramadal, Håvard (2008). Cardiac-restricted expression of the carboxyl-terminal fragment of GRK3 uncovers distinct functions of GRK3 in regulation of cardiac contractility and growth - GRK3 controls cardiac alpha(1)-adrenergic receptor responsiveness. Journal of Biological Chemistry.  ISSN 0021-9258.  283 . doi: 10.1074/jbc.M708912200
  • Gravning, Jørgen A.; Vege, Åshild & Kjekshus, John (2006). Plutselig uventet dødsfall etter perkutan koronar intervensjon. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  24(126), s 2111- 2113

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  • Gravning, Jørgen A. (2013). Protein beskytter mot hjertesvikt.
  • Gravning, Jørgen A. (2013). Pulmonal hypertensjon i frakkelommen. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  133, s 1222
  • Gravning, Jørgen A. (2013). Sensitive eller vanlige troponinanalyser ved koronare stenoser?. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  133, s 1301
  • Gravning, Jørgen A. & Attramadal, Håvard (2013). Cardioprotective Mechanisms in Ischemia-Reperfusion Injury and Heart Failure - Experimental and Clinical Studies Dissecting the Functional Effects of Connective Tissue Growth Factor (CTGF/CCN2) in the Heart.
  • Gravning, Jørgen A.; Askevold, Erik Tandberg; Nymo, Ståle Haugset; Ueland, Thor; Wergeland, Ragnhild; Wikstrand, J; Aukrust, Pål; Gullestad, Lars & Kjekshus, John (2012). Prognostic impact of high-sensitive troponin T assessment in chronic heart failure and interaction with statin therapy. Results from CORONA. European Heart Journal.  ISSN 0195-668X.  33, s 644- 645
  • Bergestuen, Deidi Ann; Gravning, Jørgen A.; Haugaa, Kristina; Sahakyan, Laura G.; Aakhus, Svend; Carlsen, Espen; Øie, Erik; Aukrust, Pål; Attramadal, Håvard & Edvardsen, Thor (2010). Plasma CCN2/Connective Tissue Growth Factor is Associated with Right Ventricular Dysfunction in Patients with Neuroendocrine Tumors. Neuroendocrinology.  ISSN 0028-3835.  92(1), s 19- 19
  • Gravning, Jørgen A.; Ahmed, Muhammad Shakil; Qvigstad, Eirik; Sagave, Julia Fritzi; Krobert, Kurt Allen; Edvardsen, Thor; Valen, Guro; Skomedal, Tor; Osnes, Jan-Bjørn & Attramadal, Håvard (2009). CCN2/CTGF - Connective Tissue Growth Factor - Reduces beta-Adrenergic Receptor Responsiveness and Catecholamine-Induced Cardiotoxicity by Upregulation of Cardiac Myocyte G Protein-Coupled Receptor Kinase-5. Circulation.  ISSN 0009-7322.  120(18), s S720- S720
  • Gravning, Jørgen A.; Attramadal, Håvard; Martinov, Vladimir Nikolkaev & Ahmed, Muhammad Shakil (2009). CCN2/CTGF, Connective Tissue Growth Factor, Prevents Heart Failure and Improves Survival After Myocardial Infarction. Circulation.  ISSN 0009-7322.  120(18), s S719- S719
  • Gravning, Jørgen Amundsen; Ahmed, MS; Qvigstad, E; Sagave, JF; Krobert, KA; Edvardsen, Thor; Valen, G; Skomedal, T; Osnes, JB & Attramadal, Håvard (2009). CCN2/CTGF - Connective Tissue Growth Factor - Reduces ?-Adrenergic Receptor Responsiveness and Catecholamine-Induced Cardiotoxicity by Upregulation of Cardiac Myocyte G Protein-Coupled Receptor Kinase-5.
  • Gravning, Jørgen Amundsen; Attramadal, Håvard; Martinov, VN & Ahmed, MS (2009). CCN2/CTGF, Connective Tissue Growth Factor, Prevents Heart Failure and Improves Survival After Myocardial Infarction.
  • Czibik, Gabor Tamas; Gravning, Jørgen Amundsen; Martinov, Vladimir Nikolkaev; Attramadal, Håvard & Valen, Guro (2008). Remote delivery of DNA encoding for hypoxia-inducible factor 1 alpha protects against myocardial remodeling in vivo. Journal of Molecular and Cellular Cardiology.  ISSN 0022-2828.  44, s 736- 737 . doi: 10.1016/j.yjmcc.2008.02.062
  • Gravning, Jørgen Amundsen; Ahmed, Muhammad Shakil; Qvigstad, Erik; Sagave, Julia Fritzi; Krobert, Kurt Allen; Edvardsen, Thor; Valen, Guro; Skomedal, Tor; Osnes, Jan-Bjørn & Attramadal, Håvard (2008). Connective tissue growth factor (CTGF/CCN2) desensitizes myocardial beta-adrenergic receptor signaling and inhibits isoproterenol induced hypertrophy.
  • Gravning, Jørgen Amundsen & Kjekshus, John (2008). The perfect biomarker in acute coronary syndrome: a challenge for diagnosis, prognosis, and treatment. European Heart Journal.  ISSN 0195-668X.  29(23), s 2827- 2828 . doi: 10.1093/eurheartj/ehn489
  • Ahmed, Muhammad Shakil; von Lueder, Thomas Gero; Gravning, Jørgen A.; Edvardsen, Thor; Smiseth, Otto A. & Attramadal, Håvard (2007). Connective tissue growth factor inhibits myocardial growth, stimulates fibrosis, but preserves myocardial function in chronic pressure overload.
  • Gravning, Jørgen A.; Ahmed, Shakil Muhammed; Martinov, V; von Lueder, Thomas Gero; Czibik, Gabor Tamas; Edvardsen, Thor; Smiseth, Otto A.; Valen, Guro & Attramadal, Håvard (2007). Novel cardioprotective role of connective tissue growth factor in ischemia/reperfusion injury and heart failure.
  • Gravning, Jørgen A.; von Lueder, Thomas Gero; Edvardsen, Thor; Vinge, Leif Erik; How, OJ; Ahmed, Shakil Muhammed; Larsen, T.S.; Smiseth, Otto A. & Attramadal, Håvard (2007). Inhibition of G protein-coupled receptor kinase-3 (GRK3) rescues cardiac dysfunction after pressure overload.
  • Gravning, Jørgen A.; von Lueder, Thomas Gero; Edvardsen, Thor; How, OJ; Aasum, E; Ahmed, Muhammad Shakil; Vinge, Leif Erik; Mikkelsen, Birthe Viftrup; Larsen, T.S.; Smiseth, Otto A. & Attramadal, Håvard (2006). Inhibition of G Protein-Couples Receptor Kinase-3 (GRK3) rescues cardiac dysfunction after pressure overload.

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Published Feb. 2, 2021 8:37 AM - Last modified Feb. 2, 2021 8:37 AM