Knut Dahl-Jørgensen

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Visiting address Barnesenteret Kirkeveien 166 0450 Oslo
Postal address Postboks 4956 Nydalen OUS, Ullevål 0424 Oslo

Research areas

Knut Dahl-Jørgensen has four main research areas.

The first is the ethiology and prevention of type 1 diabetes and autoimmune diseases, especially focusing the role of viruses and the interaction with the immune system in pancreatic and thyroid tissue samples.

The second area is diabetes late complications. We have long term clinical studies on microvascular complications  and the influence of glycemic control and advanced glycation.

Resently the risk of early atherosclerosis in type 1 diabetes has been the focus in several of our studies, with measurement of vessel wall thickness (IVUS, IMT, MRI) and vessel elasticity, and biochemical markers, as well as clinical data and risk factors.

In our large, nationwide clinical studies, now as part of the Childhood Diabetes Registry, we focus important issues as intensified insulin treatment and pumps, diabetic nephropathy, diet, physical activity, quality of life and psychososial problems and eating disturbances.

Projects:

Ethiology and prevention of type 1 diabetes and autoimmune diseases:

  1. Diabetes Virus Detection Project
  2. Genetic studies of the importance of copy-number polymorphism in the development of type 1 diabetes.
  3. Viruses, genetics and autoimmunity in thyroiditis. A biopsy study.

Diabetes late complications:

  1. Atherosclerosis in Childhood Diabetes
  2. Long term vascular changes in type 1 diabetes – Clinical aspects and biological markers – 30 years follow-up of the Oslo Study
  3. Advanced glycation of proteins and vascular complications in childhood diabetes
  4. Diabetic nephropathy: Hypertension and microalbuminuria in Norwegian children with type I diabetes

Clinical diabetes:

  1. Collaboration with the Norwegian Childhood Diabetes Registry (se page--). A nationwide prospective population-based study for research and quality improvement by means of benchmarking.
  2. Dietary intake, meal pattern and physical activity in children and adolescents with type 1 diabetes
  3. Diabetes in body and mind. The theory of the specific psychological processes in type 1 diabetes                
  4. Children and adolescents with diabetes - present state and future possibilities - A population-based study of factors affecting competences and treatment results in children and adolescents with Type I diabetes.
  5. Eating disturbances in childhood diabetes.
  6. Childhood diabetes and celiac disease – a population based study

Obesity and type 2 diabetes:

  1. Pathways contributing to childhood weight development and overweight in Norway. Sub-study of The Mother and Child National Cohort.

Courses taught

  • Pediatric endocrinology and diabetes
  • Adolescent medicine

Background

  • Professor of Pediatrics. Director and Senior Staff Specialist, Unit for Pediatric Endocrinology and Diabetes, Oslo University Hospital.
  • Vice-Dean Faculty of Medicine 2010-2012.
  • Dean of Faculty Division Ullevål, University of Oslo 2003-2009.
  • Master of Health Administration, University of Oslo 2003.
  • Academic degree: M.D. Christian Albrechts University, Kiel, Germany,1973, Dr.med (PhD) University of Oslo 1987. Master degree of Health Administration, University of Oslo 1993.
  • Norwegian Certificate Clinical Specialist in Pediatrics 1986 and Clinical Biochemistry 1984.

Awards/Prizes

  • The Swedish Child Diabetes Foundation’s Johnny Ludvigsson-prize for excellent research in childhood and adolescent diabetes 2014.
  • ISPAD Prize of Achievement 2013.

International honors

  • President of the International Society for Pediatric and Adolescent Diabetes (ISPAD) 2002-2004.
  • Secretary-General ISPAD1997-2002.
  • Council Member ISPAD 1991-1994.
  • Council Member, European Association for the Study of Diabetes (EASD) 2005-2008.
  • Board Member Consultative Section for Children and Adolescents of the International Diabetes Federation (IDF) 2002-2005.
  • Review Board of European Foundation for the Study of Diabetes (EFSD) 2004.
  • Member Editorial Board, Pediatric Diabetes, 2004-present.
  • Member WHO Europe Expert Group Childhood Diabetes, 1992-1998.
  • Member WHO Quality Board Childhood Diabetes,1996-2000.
  • National Coordinator the ENDIT Study. Member International  Board,1995-present.
  • National Coordinator the KIGS Study, Member International  Board. 1996-2003.

National honors

  • Chairman Diabetes Forum of Norwegian Diabetes Association, 2005- present.
  • Chairman Norwegian Study Group of Childhood Diabetes, 2007-2013.
  • Medical Board of Norwegian Diabetes Association, 2005-present.
  • Chairman Norwegian Medical Associations Subgroup for Pediatric Endocrinology and Metabolism,1994-1998.
  • Member Committee of Adolescence Medicine, Norwegian Medical Association,1992-2000.

Collaboration

Leader of  Research Group Pediatric Diabetes, Oslo Diabetes Research Centre.

Tags: Diabetes and hormones, USA, Nordic

Publications

  • Weider, Therese; Genoni, Angelo; Broccolo, Francesco; Paulsen, Trond Harder; Dahl-Jørgensen, Knut & Toniolo, Antonio [Show all 7 contributors for this article] (2022). High prevalence of common human viruses in thyroid tissue. Frontiers in Endocrinology. ISSN 1664-2392. 13. doi: 10.3389/fendo.2022.938633.
  • Välikangas, Tommi; Lietzén, Niina; Jaakkola, Maria K.; Krogvold, Lars; Eike, Morten Christoph & Kallionpää, Henna [Show all 14 contributors for this article] (2022). Pancreas whole tissue transcriptomics highlights the role of the exocrine pancreas in patients with recently diagnosed type 1 diabetes. Frontiers in Endocrinology. ISSN 1664-2392. 13:881985, p. 1–12. doi: 10.3389/fendo.2022.861985.
  • Nigi, Laura; Brusco, Noemi; Grieco, Giuseppina E.; Fignani, Daniela; Licata, Giada & Formichi, Caterina [Show all 13 contributors for this article] (2022). Increased Expression of Viral Sensor MDA5 in Pancreatic Islets and in Hormone-Negative Endocrine Cells in Recent Onset Type 1 Diabetic Donors. Frontiers in Immunology. ISSN 1664-3224. 13, p. 1–12. doi: 10.3389/fimmu.2022.833141.
  • Rodriguez-Calvo, Teresa; Krogvold, Lars; Amirian, Natalie; Dahl-Jørgensen, Knut & von Herrath, Matthias (2021). One in Ten CD8+ Cells in the Pancreas of Living Individuals With Recent-Onset Type 1 Diabetes Recognizes the Preproinsulin Epitope PPI15-24 . Diabetes. ISSN 0012-1797. 70(3), p. 752–758. doi: 10.2337/db20-0908.
  • Veiby, Nina; Simeunovic, Aida; Heier, Martin; Brunborg, Cathrine; Saddique, Naila & Moe, Morten C. [Show all 9 contributors for this article] (2021). Retinal venular oxygen saturation is associated with non-proliferative diabetic retinopathy in young patients with type 1 diabetes. Acta Ophthalmologica. ISSN 1755-375X. doi: 10.1111/aos.15018. Full text in Research Archive
  • Oikarinen, Sami; Krogvold, Lars; Edwin, Bjørn; Buanes, Trond; Korsgren, Olle & Laiho, Jutta E. [Show all 13 contributors for this article] (2021). Characterisation of enterovirus RNA detected in the pancreas and other specimens of live patients with newly diagnosed type 1 diabetes in the DiViD study. Diabetologia. ISSN 0012-186X. 64, p. 2491–2501. doi: 10.1007/s00125-021-05525-0. Full text in Research Archive
  • Wisting, Line Norøm; Haugvik, Severina; Wennersberg, Anne Louise; Stice, Eric; Hage, Trine Wiig & Olmsted, Marion P. [Show all 11 contributors for this article] (2021). Feasibility of a virtually delivered eating disorder preventionprogram for young females with type 1 diabetes. International Journal of Eating Disorders. ISSN 0276-3478. p. 1–11. doi: 10.1002/eat.23578. Full text in Research Archive
  • Poma, Anello Marcello; Hammerstad, Sarah Salehi; Genoni, Angelo; Basolo, Alessio; Dahl-Jorgensen, Knut & Toniolo, Antonio (2021). Immune transcriptome of cells infected with enterovirus strains obtained from cases of autoimmune thyroid disease. Microorganisms. ISSN 2076-2607. 9(4), p. 1–16. doi: 10.3390/microorganisms9040876.
  • Pedersen, Kristina; Haupt-Jorgensen, Martin; Krogvold, Lars; Kaur, Simranjeet; Gerling, Ivan C. & Pociot, Flemming [Show all 8 contributors for this article] (2021). Genetic predisposition in the 2′-5′A pathway in the development of type 1 diabetes: potential contribution to dysregulation of innate antiviral immunity. Diabetologia. ISSN 0012-186X. 64(8), p. 1805–1815. doi: 10.1007/s00125-021-05469-5.
  • Weider, Therese; Richardson, Sarah J.; Morgan, Noel G.; Paulsen, Trond Harder; Dahl-Jørgensen, Knut & Hammerstad, Sara Salehi (2021). HLA Class I Upregulation and Antiviral Immune Responses in Graves Disease. Journal of Clinical Endocrinology and Metabolism (JCEM). ISSN 0021-972X. 106(4), p. 1763–1774. doi: 10.1210/clinem/dgaa958. Full text in Research Archive
  • Sever, Dror; Hershko-Moshe, Anat; Srivastava, Rohit; Eldor, Roy; Hibsher, Daniel & Keren-Shaul, Hadas [Show all 13 contributors for this article] (2021). NF-κB activity during pancreas development regulates adult β-cell mass by modulating neonatal β-cell proliferation and apoptosis. Cell death discovery. ISSN 2058-7716. 7(1), p. 1–16. doi: 10.1038/s41420-020-00386-9.
  • Colli, Maikel L.; Ramos-Rodríguez, Mireia; Nakayasu, Ernesto S.; Alvelos, Maria I.; Lopes, Miguel & Hill, Jessica L.E. [Show all 22 contributors for this article] (2020). An integrated multi-omics approach identifies the landscape of interferon-α-mediated responses of human pancreatic beta cells. Nature Communications. ISSN 2041-1723. 11:2584, p. 1–17. doi: 10.1038/s41467-020-16327-0.
  • Veiby, Nina; Simeunovic, Aida; Heier, Martin; Brunborg, Cathrine; Saddique, Naila & Moe, Morten Carsten [Show all 9 contributors for this article] (2020). Venular oxygen saturation is increased in young patients with type 1 diabetes and mild nonproliferative diabetic retinopathy. Acta Ophthalmologica. ISSN 1755-375X. 98(8), p. 800–807. doi: 10.1111/aos.14462.
  • Weider, Therese; Richardson, Sarah; Morgan, Noel; Paulsen, Trond; Dahl-Jørgensen, Knut & Hammerstad, Sara Salehi (2020). Upregulation of HLA Class i and Antiviral Tissue Responses in Hashimoto's Thyroiditis. Thyroid. ISSN 1050-7256. 30(3), p. 432–442. doi: 10.1089/thy.2019.0607. Full text in Research Archive
  • Anderzén, Johan; Hermann, Julia M.; Samuelsson, Ulf; Charalampopoulos, Dimitrios; Svensson, Jannet & Skrivarhaug, Torild [Show all 27 contributors for this article] (2020). International benchmarking in type 1 diabetes: Large difference in childhood HbA1c between eight high-income countries but similar rise during adolescence—A quality registry study. Pediatric Diabetes. ISSN 1399-543X. 21(4), p. 621–627. doi: 10.1111/pedi.13014.
  • Veiby, Nina; Simeunovic, Aida; Heier, Martin; Brunborg, Cathrine; Saddique, Naila & Moe, Morten Carsten [Show all 9 contributors for this article] (2020). Associations between macular OCT angiography and nonproliferative diabetic retinopathy in young patients with type 1 diabetes mellitus. Journal of Diabetes Research. ISSN 2314-6745. 2020, p. 1–12. doi: 10.1155/2020/8849116. Full text in Research Archive
  • Wisting, Line Norøm; Siegwarth, Cecilie; Skrivarhaug, Torild; Dahl-Jørgensen, Knut & Rø, Øyvind (2020). The impact of psychological aspects, age, and BMI on eating disorder psychopathology among adult males and females with type 1 diabetes. Health Psychology Open (HPO). ISSN 2055-1029. 7(2). doi: 10.1177/2055102920975969. Full text in Research Archive
  • Nigi, Laura; Brusco, Noemi; Grieco, Giuseppina E.; Licata, Giada; Krogvold, Lars & Marselli, Lorella [Show all 13 contributors for this article] (2020). Pancreatic alpha-cells contribute together with beta-cells to CXCL10 expression in type 1 diabetes. Frontiers in Endocrinology. ISSN 1664-2392. 11:630, p. 1–13. doi: 10.3389/fendo.2020.00630. Full text in Research Archive
  • Bratset, Vibeke; MARGEIRSDOTTIR, HANNA DIS; Heier, Martin; Solheim, Svein; Arnesen, Harald & Dahl-Jørgensen, Knut [Show all 7 contributors for this article] (2020). Procoagulant activity in children and adolescents on intensive insulin therapy. Pediatric Diabetes. ISSN 1399-543X. 21(3), p. 496–504. doi: 10.1111/pedi.12978. Full text in Research Archive
  • Bratset, Vibeke; MARGEIRSDOTTIR, HANNA DIS; Chiva-Blanch, Gemma; Heier, Martin; Solheim, Svein & Arnesen, Harald [Show all 8 contributors for this article] (2020). Annexin V+ Microvesicles in Children and Adolescents with Type 1 Diabetes: A Prospective Cohort Study. Journal of Diabetes Research. ISSN 2314-6745. 2020, p. 1–8. doi: 10.1155/2020/7216863. Full text in Research Archive
  • Rajendran, Sakthi; Anquetil, Florence; Quesada-Masachs, Estefania; Graef, Madeleine; Gonzalez, Nathaly & McArdle, Sara [Show all 10 contributors for this article] (2019). IL-6 is present in beta and alpha cells in human pancreatic islets: Expression is reduced in subjects with type 1 diabetes. Clinical Immunology. ISSN 1521-6616. 211. doi: 10.1016/j.clim.2019.108320.
  • Seiron, Peter; Wiberg, Anna; Kuric, Enida; Krogvold, Lars; Jahnsen, Frode Lars & Dahl-Jørgensen, Knut [Show all 8 contributors for this article] (2019). Characterisation of the endocrine pancreas in type 1 diabetes: islet size is maintained but islet number is markedly reduced. The journal of pathology. Clinical research. ISSN 2056-4538. 5(4), p. 248–255. doi: 10.1002/cjp2.140.
  • Russell, Mark A.; Redick, Sambra; Blodgett, David M.; Richardson, Sarah J.; Leete, Pia & Krogvold, Lars [Show all 20 contributors for this article] (2019). HLA class II antigen processing and presentation pathway components demonstrated by transcriptome and protein analyses of islet ?-cells from donors with type 1 diabetes. Diabetes. ISSN 0012-1797. 68(5), p. 988–1001. doi: 10.2337/db18-0686.
  • Wisting, Line Norøm; Rø, Astrid Valborg; Skrivarhaug, Torild; Dahl-Jørgensen, Knut & Rø, Øyvind (2019). Disturbed eating, illness perceptions, and coping among adults with type 1 diabetes on intensified insulin treatment, and their associations with metabolic control. Journal of Health Psychology. ISSN 1359-1053. p. 1–13. doi: 10.1177/1359105319840688. Full text in Research Archive
  • Dunne, Jessica L.; Richardson, Sarah J.; Atkinson, Mark A.; Craig, Maria E.; Dahl-Jørgensen, Knut & Flodström-Tullberg, Malin [Show all 12 contributors for this article] (2019). Rationale for enteroviral vaccination and antiviral therapies in human type 1 diabetes. Diabetologia. ISSN 0012-186X. 62(5), p. 744–753. doi: 10.1007/s00125-019-4811-7. Full text in Research Archive
  • Wisting, Line Norøm; Wonderlich, Joseph; Skrivarhaug, Torild; Dahl-Jørgensen, Knut & Rø, Øyvind (2019). Psychometric properties and factor structure of the diabetes eating problem survey - revised (DEPS-R) among adult males and females with type 1 diabetes. Journal of Eating Disorders. ISSN 2050-2974. 7:2, p. 1–7. doi: 10.1186/s40337-018-0232-0. Full text in Research Archive
  • Vecchio, Federica; Lo Buono, Nicola; Stabilini, Angela; Nigi, Laura; Dufort, Matthew J. & Geyer, Susan [Show all 23 contributors for this article] (2018). Abnormal neutrophil signature in the blood and pancreas of presymptomatic and symptomatic type 1 diabetes . JCI Insight. ISSN 2379-3708. 3(18), p. 1–17. doi: 10.1172/jci.insight.122146.
  • Colli, Maikel L.; Hill, Jessica L.E.; Marroqui, Laura; Chaffey, Jessica; Dos Santos, Reinaldo S. & Leete, Pia [Show all 17 contributors for this article] (2018). PDL1 is expressed in the islets of people with type 1 diabetes and is up-regulated by interferons-α and-γ via IRF1 induction. EBioMedicine. ISSN 2352-3964. 36, p. 367–375. doi: 10.1016/j.ebiom.2018.09.040.
  • Horwitz, Elad; Krogvold, Lars; Zhitomirsky, Sophia; Swisa, Avital; Fischman, Maya & Lax, Tsuria [Show all 17 contributors for this article] (2018). B-cell DNA damage response promotes islet inflammation in type 1 diabetes. Diabetes. ISSN 0012-1797. 67(11), p. 2305–2318. doi: 10.2337/db17-1006.
  • Heier, Martin; Nygaard, Cathrine Skorpen; Brunborg, Cathrine; Seljeflot, Ingebjørg; MARGEIRSDOTTIR, HANNA DIS & Hanssen, Kristian Folkvord [Show all 8 contributors for this article] (2018). Preserved endothelial function in young adults with type 1 diabetes. PLOS ONE. ISSN 1932-6203. 13:e0206523(10), p. 1–8. doi: 10.1371/journal.pone.0206523. Full text in Research Archive
  • Anquetil, Florence; Mondanelli, Giada; Gonzalez, Nathaly; Rodriguez Calvo, Teresa; Zapardiel Gonzalo, Jose & Krogvold, Lars [Show all 11 contributors for this article] (2018). Loss of IDO1 expression from human pancreatic β-cells precedes their destruction during the development of Type 1 diabetes. Diabetes. ISSN 0012-1797. 67(9), p. 1858–1866. doi: 10.2337/db17-1281.
  • Kuric, Enida; Krogvold, Lars; Hanssen, Kristian Folkvord; Dahl-Jørgensen, Knut; Skog, Oskar & Korsgren, Olle (2018). No evidence for presence of mucosal-associated invariant T cells in the insulitic lesions in patients recently diagnosed with Type 1 diabetes. American Journal of Pathology. ISSN 0002-9440. 188(8), p. 1744–1748. doi: 10.1016/j.ajpath.2018.04.009.
  • Wisting, Line Norøm; Skrivarhaug, Torild; Dahl-Jørgensen, Knut & Rø, Øyvind (2018). Prevalence of disturbed eating behavior and associated symptoms of anxiety and depression among adult males and females with type 1 diabetes. Journal of Eating Disorders. ISSN 2050-2974. 6(28), p. 1–10. doi: 10.1186/s40337-018-0209-z.
  • Reddy, Shiva; Krogvold, Lars; Martin, Charlton; Holland, Rebecca; Choi, Jaimin & Woo, Hannah [Show all 8 contributors for this article] (2018). Distribution of IL-1β immunoreactive cells in pancreatic biopsies from living volunteers with new-onset type 1 diabetes: comparison with donors without diabetes and with longer duration of disease. Diabetologia. ISSN 0012-186X. 61(6), p. 1362–1373. doi: 10.1007/s00125-018-4600-8. Full text in Research Archive
  • Charalampopoulos, Dimitrios; Hermann, Julia M.; Svensson, Jannet; Skrivarhaug, Torild; Maahs, David M. & Åkesson, Karin [Show all 24 contributors for this article] (2018). Exploring variation in glycemic control across and within eight high-income countries: A cross sectional analysis of 64,666 children and adolescents with type 1 diabetes. Diabetes Care. ISSN 0149-5992. 41(6), p. 1180–1187. doi: 10.2337/dc17-2271.
  • Holm, Laurits J.; Krogvold, Lars; Hasselby, Jane P.; Kaur, Simranjeet; Claessens, Laura A. & Russell, Mark A. [Show all 15 contributors for this article] (2018). Abnormal islet sphingolipid metabolism in type 1 diabetes. Diabetologia. ISSN 0012-186X. 61(7), p. 1650–1661. doi: 10.1007/s00125-018-4614-2. Full text in Research Archive
  • Heier, Martin; Stensæth, Knut Haakon; Brunborg, Cathrine; Seljeflot, Ingebjørg; Margeirsdottir, Hanna Dis & Hanssen, Kristian Folkvord [Show all 7 contributors for this article] (2018). Increased arterial stiffness in childhood onset diabetes: A cardiovascular magnetic resonance study. European Heart Journal-Cardiovascular Imaging. ISSN 2047-2404. 19(6), p. 694–700. doi: 10.1093/ehjci/jex178.
  • Viken, Marte K; Flåm, Siri Tennebø; Skrivarhaug, Torild; Amundsen, Silja Svanstrøm; Sollid, Ludvig Magne & Drivvoll, Ann Kristin [Show all 9 contributors for this article] (2017). HLA class II alleles in Norwegian patients with coexisting type 1 diabetes and celiac disease. HLA. ISSN 2059-2302. 89(5), p. 278–284. doi: 10.1111/tan.12986.
  • Wisting, Line Norøm; Reas, Deborah; Bang, Lasse; Skrivarhaug, Torild; Dahl-Jørgensen, Knut & Rø, Øyvind (2017). Eating patterns in adolescents with type 1 diabetes: Associations with metabolic control, insulin omission, and eating disorder pathology. Appetite. ISSN 0195-6663. 114, p. 226–231. doi: 10.1016/j.appet.2017.03.035. Full text in Research Archive
  • Rodriguez-Calvo, Teresa; Zapardiel-Gonzalo, Jose; Amirian, Natalie; Castillo, Ericka; Lajevardi, Yasaman & Krogvold, Lars [Show all 8 contributors for this article] (2017). Increase in pancreatic proinsulin and preservation of β-cell mass in autoantibody-positive donors prior to type 1 diabetes onset. Diabetes. ISSN 0012-1797. 66(5), p. 1334–1345. doi: 10.2337/db16-1343. Full text in Research Archive
  • Heier, Martin; Borja, Mark S.; Brunborg, Cathrine; Seljeflot, Ingebjørg; MARGEIRSDOTTIR, HANNA DIS & Hanssen, Kristian Folkvord [Show all 8 contributors for this article] (2017). Reduced HDL function in children and young adults with type 1 diabetes. Cardiovascular Diabetology. ISSN 1475-2840. 16:85, p. 1–8. doi: 10.1186/s12933-017-0570-2. Full text in Research Archive
  • Lundberg, Marcus; Lindqvist, Andreas; Wierup, Nils; Krogvold, Lars; Dahl-Jørgensen, Knut & Skog, Oskar (2017). The density of parasympathetic axons is reduced in the exocrine pancreas of individuals recently diagnosed with type 1 diabetes. PLOS ONE. ISSN 1932-6203. 12(6). doi: 10.1371/journal.pone.0179911.
  • Brunvand, Leif; Heier, Martin; Brunborg, Cathrine; Hanssen, Kristian Folkvord; Fugelseth, Drude & STENSÆTH, KNUT HAAKON [Show all 8 contributors for this article] (2017). Advanced glycation end products in children with type 1 diabetes and early reduced diastolic heart function. BMC Cardiovascular Disorders. ISSN 1471-2261. 17(133). doi: 10.1186/s12872-017-0551-0. Full text in Research Archive
  • Kuric, Enida; Seiron, Peter; Krogvold, Lars; Edwin, Bjørn; Buanes, Trond & Hanssen, Kristian Folkvord [Show all 9 contributors for this article] (2017). Demonstration of tissue resident memory CD8 T cells in insulitic lesions in adult patients with recent-onset type 1 diabetes. American Journal of Pathology. ISSN 0002-9440. 187(3), p. 581–588. doi: 10.1016/j.ajpath.2016.11.002.
  • Martin, Charlton; Krogvold, Lars; Farik, Shebani; Amirapu, Satya; Wu, Fiona & Reddy, Shiva [Show all 7 contributors for this article] (2017). An immunohistochemical study of nitrotyrosine expression in pancreatic islets of cases with increasing duration of type 1 diabetes and without diabetes. Histochemistry and Cell Biology. ISSN 0948-6143. 147(5), p. 605–623. doi: 10.1007/s00418-016-1533-5.
  • Hodik, Monika; Anagandula, Mahesh; Fuxe, Jonas; Krogvold, Lars; Dahl-Jørgensen, Knut & Hyöty, Heikki [Show all 8 contributors for this article] (2016). Coxsackie-adenovirus receptor expression is enhanced in pancreas from patients with type 1 diabetes. BMJ Open Diabetes Research & Care. ISSN 2052-4897. 4:219(1). doi: 10.1136/bmjdrc-2016-000219.
  • Wisting, Line Norøm; Bang, Lasse; Skrivarhaug, Torild; Dahl-Jørgensen, Knut & Rø, Øyvind (2016). Psychological barriers to optimal insulin therapy: More concerns in adolescent females than males. BMJ Open Diabetes Research & Care. ISSN 2052-4897. 4(1). doi: 10.1136/bmjdrc-2016-000203.
  • Lundberg, Marcus; Krogvold, Lars; Kuric, Enida; Dahl-Jørgensen, Knut & Skog, Oskar (2016). Expression of interferon-stimulated genes in insulitic pancreatic islets of patients recently diagnosed with type 1 diabetes. Diabetes. ISSN 0012-1797. 65(10), p. 3104–3110. doi: 10.2337/db16-0616.
  • Richardson, Sarah J.; Rodriguez-Calvo, Teresa; Gerling, Ivan C.; Mathews, Clayton E.; Kaddis, John S. & Russell, Mark A. [Show all 14 contributors for this article] (2016). Islet cell hyperexpression of HLA class I antigens: a defining feature in type 1 diabetes. Diabetologia. ISSN 0012-186X. 59(11), p. 2448–2458. doi: 10.1007/s00125-016-4067-4.
  • Leete, Pia; Willcox, Abby; Krogvold, Lars; Dahl-Jørgensen, Knut; Foulis, Alan K. & Richardson, Sarah J. [Show all 7 contributors for this article] (2016). Differential insulitic profiles determine the extent of β-cell destruction and the age at onset of type 1 diabetes. Diabetes. ISSN 0012-1797. 65(5), p. 1362–1369. doi: 10.2337/db15-1615.
  • Brunvand, Leif; Fugelseth, Drude; STENSÆTH, KNUT-HAAKON; Dahl-Jørgensen, Knut & MARGEIRSDOTTIR, HANNA DIS (2016). Early reduced myocardial diastolic function in children and adolescents with type 1 diabetes mellitus a population-based study. BMC Cardiovascular Disorders. ISSN 1471-2261. 16(103). doi: 10.1186/s12872-016-0288-1. Full text in Research Archive
  • Wisting, Line Norøm; Bang, Lasse; Natvig, Henrik; Skrivarhaug, Torild; Dahl-Jørgensen, Knut & Lask, Bryan [Show all 7 contributors for this article] (2016). Metabolic Control and Illness Perceptions in Adolescents with Type 1 Diabetes. Journal of Diabetes Research. ISSN 2314-6745. 2016. doi: 10.1155/2016/3486094.
  • Krogvold, Lars; Skog, Oskar; Sundström, Görel; Edwin, Bjørn; Buanes, Trond & Hanssen, Kristian Folkvord [Show all 10 contributors for this article] (2015). Function of isolated pancreatic islets from patients at onset of type 1 diabetes: Insulin secretion can be restored after some days in a nondiabetogenic environment in vitro results from the divid study. Diabetes. ISSN 0012-1797. 64(7), p. 2506–2512. doi: 10.2337/db14-1911.
  • Krogvold, Lars; Wiberg, Anna; Edwin, Bjørn; Buanes, Trond; Jahnsen, Frode Lars & Hanssen, Kristian Folkvord [Show all 10 contributors for this article] (2015). Insulitis and characterisation of infiltrating T cells in surgical pancreatic tail resections from patients at onset of type 1 diabetes. Diabetologia. ISSN 0012-186X. 59(3), p. 492–501. doi: 10.1007/s00125-015-3820-4.
  • Wisting, Line Norøm; Bang, Lasse; Skrivarhaug, Torild; Dahl-Jørgensen, Knut & Rø, Øyvind (2015). Adolescents with type 1 diabetes - The impact of gender, age, and health-related functioning on eating disorder psychopathology. PLOS ONE. ISSN 1932-6203. 10(11). doi: 10.1371/journal.pone.0141386.
  • Heier, Martin; MARGEIRSDOTTIR, HANNA DIS; Gaarder, Mario; STENSÆTH, KNUT-HAAKON; Brunborg, Cathrine & Torjesen, Peter A [Show all 9 contributors for this article] (2015). Soluble RAGE and atherosclerosis in youth with type 1 diabetes: A 5-year follow-up study. Cardiovascular Diabetology. ISSN 1475-2840. 14(126). doi: 10.1186/s12933-015-0292-2.
  • Krogvold, Lars; Edwin, Bjørn; Buanes, Trond; Frisk, Gun; Skog, Oskar & Anagandula, Mahesh [Show all 19 contributors for this article] (2015). Detection of a low-grade enteroviral infection in the islets of langerhans of living patients newly diagnosed with type 1 diabetes. Diabetes. ISSN 0012-1797. 64(5), p. 1682–1687. doi: 10.2337/db14-1370.
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  • Heier, Martin; MARGEIRSDOTTIR, HANNA DIS; Brunborg, Cathrine; Hanssen, Kristian Folkvord; Dahl-Jørgensen, Knut & Seljeflot, Ingebjørg (2015). Inflammation in childhood type-1 diabetes; influence of glycemic control. Atherosclerosis. ISSN 0021-9150. 238, p. 33–37. doi: 10.1016/j.atherosclerosis.2014.11.018.
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  • Hammerstad, Sara Salehi; Jahnsen, Frode Lars; Tauriainen, Sisko; Hyöty, Heikki; Paulsen, Trond Harder & Nordheim, Ingrid [Show all 7 contributors for this article] (2014). Immunological changes and increased expression of myxovirus resistance protein A in thyroid tissue of patients with recent onset and untreated graves' disease. Thyroid. ISSN 1050-7256. 24(3), p. 537–544. doi: 10.1089/thy.2013.0287.
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  • Hammerstad, Sara Salehi; Tauriainen, S; Hyöty, Heikki; Paulsen, Trond Harder; Nordheim, Ingrid & Dahl-Jørgensen, Knut (2013). Detection of enterovirus in the thyroid tissue of patients with graves' disease. Journal of Medical Virology. ISSN 0146-6615. 85(3), p. 512–518. doi: 10.1002/jmv.23476.
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  • Wisting, Line Norøm; Frøisland, Dag Helge; Skrivarhaug, Torild; Dahl-Jørgensen, Knut & Rø, Øyvind (2013). Disturbed Eating Behavior and Omission of Insulin in Adolescents Receiving Intensified Insulin Treatment A nationwide population-based study. Diabetes Care. ISSN 0149-5992. 36(11), p. 3382–3387. doi: 10.2337/dc13-0431.
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  • Frøisland, Dag Helge; Graue, Marit; Markestad, Trond; Skrivarhaug, Torild; Wentzel-Larsen, Tore & Dahl-Jørgensen, Knut (2013). Health-related quality of life among Norwegian children and adolescents with type 1 diabetes on intensive insulin treatment: a population-based study. Acta Paediatrica. ISSN 0803-5253. 102(9), p. 889–895. doi: 10.1111/apa.12312.
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  • Køpp, Unni Mette Stamnes; Dahl-Jørgensen, Knut; Stigum, Hein; Andersen, Lene Frost; Næss, Øyvind & Nystad, Wenche (2012). The associations between maternal pre-pregnancy body mass index or gestational weight change during pregnancy and body mass index of the child at 3 years of age. International Journal of Obesity. ISSN 0307-0565. 36(10), p. 1325–1331. doi: 10.1038/ijo.2012.140.
  • Frøisland, Dag Helge; Markestad, Trond; Wentzel-Larsen, Tore; Skrivarhaug, Torild; Dahl-Jørgensen, Knut & Graue, Marit (2012). Reliability and validity of the Norwegian child and parent versions of the DISABKIDS Chronic Generic Module (DCGM-37) and Diabetes-Specific Module (DSM-10). Health and Quality of Life Outcomes. ISSN 1477-7525. 10. doi: 10.1186/1477-7525-10-19.
  • Køpp, Unni Mette Stamnes; Andersen, Lene Frost; Dahl-Jørgensen, Knut; Stigum, Hein; Næss, Øyvind & Nystad, Wenche (2012). Maternal pre-pregnant body mass index, maternal weight change and offspring birthweight. Acta Obstetricia et Gynecologica Scandinavica. ISSN 0001-6349. 91(2), p. 243–249. doi: 10.1111/j.1600-0412.2011.01321.x.
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  • MARGEIRSDOTTIR, HANNA DIS; Larsen, Jakob; Kummernes, Siv Janne; Brunborg, Cathrine & Dahl-Jørgensen, Knut (2010). The establishment of a new national network leads to quality improvement in childhood diabetes: Implementation of the ISPAD Guidelines. Pediatric Diabetes. ISSN 1399-543X. 11(2), p. 88–95. doi: 10.1111/j.1399-5448.2009.00542.x.
  • MARGEIRSDOTTIR, HANNA DIS; STENSÆTH, KNUT-HAAKON; Larsen, Jacob Roald; Brunborg, Cathrine & Dahl-Jørgensen, Knut (2010). Early Signs of Atherosclerosis in Diabetic Children on Intensive Insulin Treatment A population-based study. Diabetes Care. ISSN 0149-5992. 33(9), p. 2043–2048. doi: 10.2337/dc10-0505.
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  • Bjørnvold, Marit; Munthe-Kaas, Monica Cheng; Egeland, Thore; Joner, Geir; Dahl-Jørgensen, Knut & Njølstad, Pål Rasmus [Show all 11 contributors for this article] (2009). A TLR2 polymorphism is associated with type 1 diabetes and allergic asthma. Genes and Immunity. ISSN 1466-4879. 10(2), p. 181–187. doi: 10.1038/gene.2008.100.
  • Eike, MC; Olsson, M; Undlien, DE; Dahl-Jørgensen, Knut; Joner, Geir & Rønningen, Kjersti Skjold [Show all 8 contributors for this article] (2009). Genetic variants of the HLA-A, HLA-B and AIF1 loci show independent associations with type 1 diabetes in Norwegian families. Genes and Immunity. ISSN 1466-4879. 10(2), p. 141–150. doi: 10.1038/gene.2008.88.
  • Øverby, Nina Cecilie; MARGEIRSDOTTIR, HANNA DIS; Brunborg, Cathrine; Anderssen, Sigmund; Andersen, Lene Frost & Dahl-Jørgensen, Knut (2009). Physical activity and overweight in children and adolescents using intensified insulin treatment. Pediatric Diabetes. ISSN 1399-543X. 10(2), p. 135–141. doi: 10.1111/j.1399-5448.2008.00454.x.
  • MARGEIRSDOTTIR, HANNA DIS; Larsen, JR; Kummernes, Siv Janne; Brunborg, Cathrine & Dahl-Jørgensen, Knut (2009). The establishment of a new national network leads to quality improvement in childhood diabetes: Implementation of the ISPAD Guidelines. Pediatric Diabetes. ISSN 1399-543X. doi: 10.1111/j.1399-5448.2009.00542.x.
  • Donaghue, KC; Chiarelli, F; Trotta, D; Allgrove, J & Dahl-Jørgensen, Knut (2009). Microvascular and macrovascular complications associated with diabetes in children and adolescents. Pediatric Diabetes. ISSN 1399-543X. 10, p. 195–203. doi: 10.1111/j.1399-5448.2009.00576.x.
  • Bjørnvold, Marit; Undlien, DE; Joner, Geir; Dahl-Jørgensen, Knut; Njølstad, Pål Rasmus & Akselsen, HE [Show all 9 contributors for this article] (2008). Joint effects of HLA, INS, PTPN22 and CTLA4 genes on the risk of type 1 diabetes. Diabetologia. ISSN 0012-186X. 51(4), p. 589–596. doi: 10.1007/s00125-008-0932-0.
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  • Øverby, Nina Cecilie; MARGEIRSDOTTIR, HANNA DIS; Brunborg, C; Dahl-Jørgensen, Knut & Andersen, Lene Frost (2008). Sweets, snacking habits, and skipping meals in children and adolescents on intensive insulin treatment. Pediatric Diabetes. ISSN 1399-543X. 9, p. 393–400. doi: 10.1111/j.1399-5448.2008.00381.x.
  • Eike, Morten Christoph; Olsson, M; Undlien, Dag Erik; Dahl-Jørgensen, Knut; Joner, Geir & Rønningen, Kjersti Skjold [Show all 8 contributors for this article] (2008). Genetic variants of the HLA-A, HLA-B and AIF1 loci show independent associations with type 1 diabetes in Norwegian families. Genes and Immunity. ISSN 1466-4879.
  • Øverby, Nina Cecilie; MARGEIRSDOTTIR, HANNA DIS; Brunborg, Cathrine; Anderssen, SA; Andersen, Lene Frost & Dahl-Jørgensen, Knut (2008). Physical activity and overweight in children and adolescents using intensified insulin treatment. Pediatric Diabetes. ISSN 1399-543X. doi: 10.1111/j.1399-5448.2008.00454.x.

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  • Birkebaek, Niels Holtum; Hermann, Julia M.; Hanberger, Lena; Charalampopoulos, Dimitrios; Holl, Reinhard W. & Skrivarhaug, Torild [Show all 24 contributors for this article] (2019). Center size and glycemic control: An international study with 504 centers from seven countries. Diabetes Care. ISSN 0149-5992. 42(3), p. E37–E39. doi: 10.2337/dc18-1253.
  • Dunne, Jessica L.; Richardson, Sarah J.; Atkinson, Mark A.; Craig, Maria E.; Dahl-Jørgensen, Knut & Flodström-Tullberg, Malin [Show all 10 contributors for this article] (2019). Large enteroviral vaccination studies to prevent type 1 diabetes should be well founded and rely on scientific evidence. Reply to Skog O, Klingel K, Roivainen M et al [letter]. Diabetologia. ISSN 0012-186X. 62(6), p. 1100–1103. doi: 10.1007/s00125-019-4873-6.
  • Westermark, Gunilla T.; Krogvold, Lars; Dahl-Jørgensen, Knut & Ludvigsson, Johnny (2017). Islet amyloid in recent-onset type 1 diabetes?the DiViD study. Uppsala Journal of Medical Sciences. ISSN 0300-9734. 122(3), p. 201–203. doi: 10.1080/03009734.2017.1359219.
  • Wisting, Line Norøm; Frøisland, Dag Helge; Skrivarhaug, Torild; Dahl-Jørgensen, Knut; Bang, Lasse & Natvig, Henrik [Show all 8 contributors for this article] (2015). Type 1 diabetes and Disturbed Eating Behaviors - Comorbidity, Prevalence, Psychological Correlates and Metabolic Control.
  • Borkamo, H. Styve; Drivvoll, Ann Kristin; Kummernes, Siv Janne; Dahl-Jørgensen, Knut & Skrivarhaug, Torild (2015). Reduced incidence of severe hypoglycemia and changing trends in treatment of Type 1 diabetes (T1D) in children the last 12 years in Norway - a Nationwide study.
  • Wisting, Line Norøm; Frøisland, Dag Helge; Skrivarhaug, Torild; Dahl-Jørgensen, Knut; Bang, Lasse & Natvig, Henrik [Show all 8 contributors for this article] (2015). Comorbid type 1 diabetes and disturbed eating behaviors - assessment, prevalence, psychological correlates and metabolic Control.
  • Sveen, Kari Anne; Ørstavik, Kristin; Fosmark, Dag Sigurd; Dahl-Jørgensen, Knut & Hanssen, Kristian Folkvord (2013). Retinal nerve fibre layer thickness is associated with measures of small fibre neuropathy in long-term type 1 diabetes. Diabetologia. ISSN 0012-186X. 56, p. S499–S500.
  • Viken, Marte K; Flåm, Siri Tennebø; Sollid, Ludvig Magne; Skrivarhaug, Torild; Dahl-Jørgensen, Knut & Lie, Benedicte Alexandra (2012). STUDY OF THE HLA-DRB1 AND-DQB1 GENES IN PATIENTS WITH COEXISTING TYPE 1 DIABETES AND CELIAC DISEASE. Tissue Antigens. ISSN 0001-2815. 79(6), p. 584–584.
  • MARGEIRSDOTTIR, HANNA DIS; STENSÆTH, KNUT-HAAKON; Larsen, Jacob Roald; Brunborg, Cathrine & Dahl-Jørgensen, Knut (2010). Early signs of atherosclerosis in diabetic children on intensive insulin treatment: a population based study. Diabetologia. ISSN 0012-186X. 53, p. S13–S13.
  • Haug, Jon & Dahl-Jørgensen, Knut (2010). Diabetes i kropp og sinn. Teorien om de spesifikke psykologiske prosessene ved type 1-diabetes. Unipub forlag.

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Published Apr. 13, 2011 2:34 PM - Last modified June 7, 2016 11:45 AM