Lars Nilsson

Norwegian version of this page
Phone +47-22840221
Username
Visiting address Sognsvannsveien 20 Rikshospitalet 0372 OSLO
Postal address Postboks 1057 Blindern 0316 OSLO

Academic Interests

Research on Alzheimer's disease, neurodegeneration, amyloid formation

Teaching

  • Pharmacology and PBL for medical students

Higher education and employment history

  • MSc Pharmacy, Uppsala University, 1988
  • PhD, Neurobiology, Karolinska Institutet, 1996
  • Professor Pharmacology, 2012-

Publications

  • Jendresen, Charlotte Bille; Digre, Andreas; Cui, Hao; Zhang, Xiao; Vlodavsky, Israel; Li, Jin-Ping & Nilsson, Lars (2019). Systemic LPS-induced Aβ-solubilization and clearance in AβPP-transgenic mice is diminished by heparanase overexpression. Scientific Reports.  ISSN 2045-2322.  9:4600(1), s 1- 12 . doi: 10.1038/s41598-019-40999-4
  • Nordengen, Kaja; Kirsebom, Bjørn-Eivind; Henjum, Kristi; Selnes, Per; Gisladottir, Berglind; Wettergreen, Marianne; Torsetnes, Silje Bøen; Grøntvedt, Gøril Rolfseng; Waterloo, Knut; Aarsland, Dag; Nilsson, Lars & Fladby, Tormod (2019). Glial activation and inflammation along the Alzheimer's disease continuum. Journal of Neuroinflammation.  ISSN 1742-2094.  16(46) . doi: 10.1186/s12974-019-1399-2
  • Henjum, Kristi; Paulsen, Else Quist; Zetterberg, Henrik; Blennow, Kaj; Nilsson, Lars & Watne, Leiv (2018). CSF sTREM2 in delirium - Relation to Alzheimer's disease CSF biomarkers A?42, t-tau and p-tau 11 Medical and Health Sciences 1109 Neurosciences 11 Medical and Health Sciences 1103 Clinical Sciences. Journal of Neuroinflammation.  ISSN 1742-2094.  15(1), s 1- 15 . doi: 10.1186/s12974-018-1331-1 Full text in Research Archive.
  • Jendresen, Charlotte Bille; Daws, Michael Rory & Nilsson, Lars (2018). An improved CPRG colorimetric ligand-receptor signal transduction assay based on beta-galactosidase activity in mammalian BWZ-reporter cells. Journal of pharmacological and toxicological methods.  ISSN 1056-8719.  90, s 67- 75 . doi: 10.1016/j.vascn.2017.11.004 Full text in Research Archive.
  • Jendresen, Charlotte Bille; Årskog, Vibeke Helen; Daws, Michael Rory & Nilsson, Lars (2017). The Alzheimer's disease risk factors apolipoprotein E and TREM2 are linked in a receptor signaling pathway. Journal of Neuroinflammation.  ISSN 1742-2094.  14:59, s 1- 13 . doi: 10.1186/s12974-017-0835-4
  • Henjum, Kristi; Almdahl, Ina; Årskog, Vibeke Helen; Minthon, Lennart; Hansson, Oskar; Fladby, Tormod & Nilsson, Lars (2016). Cerebrospinal fluid soluble TREM2 in aging and Alzheimer's disease. Alzheimer's Research & Therapy.  ISSN 1758-9193.  8(1) . doi: 10.1186/s13195-016-0182-1
  • Nordeman, Patrik; Johansson, Leif B.G.; Bäck, Marcus; Estrada, Sergio; Hall, Håkan; Sjölander, Daniel; Westermark, Gunilla T.; Westermark, Per; Nilsson, Lars; Hammarström, Per; Nilsson, K. Peter R. & Antoni, Gunnar (2016). <sup>11</sup>C and <sup>18</sup>F Radiolabeling of Tetra- and Pentathiophenes as PET-Ligands for Amyloid Protein Aggregates. ACS Medicinal Chemistry Letters.  ISSN 1948-5875.  7(4), s 368- 373 . doi: 10.1021/acsmedchemlett.5b00309
  • Jendresen, Charlotte Bille; Cui, Hao; Zhang, Xiao; Vlodavsky, Israel; Nilsson, Lars & Li, Jin-Ping (2015). Overexpression of heparanase lowers the amyloid burden in amyloid-β precursor Protein Transgenic mice. Journal of Biological Chemistry.  ISSN 0021-9258.  290(8), s 5053- 5064 . doi: 10.1074/jbc.M114.600569
  • Røgeberg, Magnus; Almdahl, Ina; Wettergreen, Marianne; Nilsson, Lars & Fladby, Tormod (2015). Isobaric Quantification of Cerebrospinal Fluid Amyloid-β Peptides in Alzheimer's Disease: C-Terminal Truncation Relates to Early Measures of Neurodegeneration. Journal of Proteome Research.  ISSN 1535-3893.  14(11), s 4834- 4843 . doi: 10.1021/acs.jproteome.5b00668
  • Røgeberg, Magnus; Wettergreen, Marianne; Nilsson, Lars & Fladby, Tormod (2015). Identification of amyloid beta mid-domain fragments in human cerebrospinal fluid. Biochimie.  ISSN 0300-9084.  113, s 86- 92 . doi: 10.1016/j.biochi.2015.03.022

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Published Jan. 26, 2012 9:59 AM - Last modified Aug. 13, 2018 12:14 PM