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• Blindheim, Augun; Fosså, Sophie Dorothea; Babigumira, Ronnie & Andreassen, Bettina Kulle (2021). The use of reTURB in T1 bladder cancer: a Norwegian population-based study. Scandinavian Journal of Urology.  ISSN 2168-1805.  s 1- 8 . doi: 10.1080/21681805.2021.1917652 Show summary

  Aim: To evaluate the use of repeat transurethral resection of the bladder (reTURB) in stage T1 bladdercancer and its impact on treatment and survival in a Norwegian population-based cohort. Material and methods: 1130 patients registered at the cancer Registry of Norway between 2008 and2012 with primary urothelial T1 cancer were included. Information on surgical and medical procedures was provided by the Norwegian Patient Registry. Descriptive statistics were used to evaluate characteristics of patients receiving reTURB or not within 12 weeks from primary TURB (primTURB). Survival models identified risk factors and estimated cause-specific survival rates (CSS) adjusted for sex, age, WHO grade, concomitant cis and detrusor muscle at primTURB and treatment. Results: The 648 (57%) T1 patients with reTURB were significantly younger and had more WHO high grade tumors compared to those without reTURB. Of 275 patients without detrusor muscle at primTURB 114 (41%) had no reTURB. Of reTURB patients, 45 (7%) had muscle invasive tumor, 110 (17%) T1 and 378 (58%) Ta, cis or T0. Two-thirds of 81 patients receiving early cystectomy after reTURB had T1 or muscle invasive bladder cancer at reTURB. ReTURB did not impact adjusted CSS, but patients with T1 at reTURB had significantly lower CSS than those with < T1 conditions. Conclusions: Almost half of the T1 patients did not undergo reTURB as recommended in guidelines. We show that reTURB makes the histology result more reliable with impact on both treatment and survival. Our results support the use of reTURB as recommended by EAU guidelines.

• Aas, Kirsti; Fosså, Sophie Dorothea; Myklebust, Tor Åge; Møller, Bjørn; Kvåle, Rune; Vlatkovic, Ljiljana & Berge, Viktor (2020). Increased curative treatment is associated with decreased prostate cancer-specific and overall mortality in senior adults with high-risk prostate cancer; results from a national registry-based cohort study. Cancer Medicine.  ISSN 2045-7634.  9(18), s 6646- 6657 . doi: 10.1002/cam4.3297 Full text in Research Archive.
• Blindheim, Augun Jodis; Fosså, Sophie Dorothea; Babigumira, Ronnie; Myklebust, Tor Åge; Haug, Erik Skaaheim; Arum, Carl-Jørgen & Kulle, Bettina (2020). T1 bladder cancer in Norway: treatment and survival. Scandinavian Journal of Urology.  ISSN 2168-1805.  54(5), s 370- 375 . doi: 10.1080/21681805.2020.1803401 Full text in Research Archive.
• Bøhn, Synne-Kristin Hoffart; Lie, Hanne Cathrine; Reinertsen, Kristin Valborg; Fosså, Sophie Dorothea; Haugnes, Hege Sagstuen; Kiserud, Cecilie E.; Loge, Jon Håvard; Wisløff, Torbjørn & Thorsen, Lene (2020). Lifestyle among long-term survivors of cancers in young adulthood. Supportive Care in Cancer.  ISSN 0941-4355.  29(1), s 289- 300 . doi: 10.1007/s00520-020-05445-6 Full text in Research Archive. Show summary

  Abstract Purpose To investigate lifestyle in a population-based sample of long-term (≥ 5 years since diagnosis) young adult cancer survivors (YACSs), and explore factors associated with not meeting the lifestyle guidelines for physical activity (PA), body mass index (BMI), and smoking. Methods YACSs (n = 3558) diagnosed with breast cancer (BC), colorectal cancer (CRC), non-Hodgkin lymphoma (NHL), acute lymphoblastic leukemia (ALL), or localized malignant melanoma (MM) between the ages of 19 and 39 years and treated between 1985 and 2009 were invited to complete a mailed questionnaire. Survivors of localized MM treated with limited skin surgery served as a reference group for treatment burden. Results In total, 1488 YACSs responded (42%), and 1056 YACSs were evaluable and included in the present study (74% females, average age at survey 49 years, average 15 years since diagnosis). Forty-four percent did not meet PA guidelines, 50% reported BMI ≥ 25 and 20% smoked, with no statistically significant differences across diagnostic groups. Male gender, education ≤ 13 years, comorbidity, lymphedema, pain, chronic fatigue, and depressive symptoms were associated with not meeting single and/or an increasing number of lifestyle guidelines. Conclusion A large proportion of long-term YACSs do not meet the lifestyle guidelines for PA, BMI, and/or smoking. Non-adherence to guidelines is associated with several late effects and/or comorbidities that should be considered when designing lifestyle interventions for YACSs.

• Dahl, Alv A; Bentzen, Anne Gry; Fosså, Sophie Dorothea; Hess, Siri Lothe; Steen, Rita & Kiserud, Cecilie E. (2020). Long-term cervical cancer survivors on disability pension: a subgroup in need of attention from health care providers. Journal of cancer survivorship.  ISSN 1932-2259.  14(4), s 578- 585 . doi: 10.1007/s11764-020-00877-9 Full text in Research Archive.
• Dahl, Alv A; Bentzen, Anne Gry; Fosså, Sophie Dorothea; Hess, Siri Lothe; Steen, Rita; Vistad, Ingvild & Kiserud, Cecilie E. (2020). Sexual inactivity during the last 4 weeks in long-term cervical cancer survivors: Prevalence and associated factors. Journal of Sexual Medicine.  ISSN 1743-6095.  17(7), s 1359- 1369 . doi: 10.1016/j.jsxm.2020.03.010 Full text in Research Archive.
• Dahl, Alv A; Brennhovd, Bjørn; Fosså, Sophie Dorothea & Axcrona, Karol (2020). A cross-sectional study of current work ability after radical prostatectomy. BMC Urology.  ISSN 1471-2490.  20(1), s 1- 7 . doi: 10.1186/s12894-020-0579-9 Full text in Research Archive.
• Dahl, Alv A; Fosså, Sophie Dorothea; Brennhovd, Bjørn & Axcrona, Karol (2020). The EPIC-26 domain scores after radical prostatectomy are associated with the personality trait of neuroticism. International Urology and Nephrology.  ISSN 0301-1623. . doi: 10.1007/s11255-020-02688-4 Show summary

  Purpose The personality trait of neuroticism represents vulnerability for mental distress to somatic health problems. There are few studies of neuroticism in prostate cancer patients. This study examines the levels of self-reported adverse effects (AEs) after robot-assisted radical prostatectomy (RALP) in Norwegian men with high or low levels of neuroticism. Neuroticism is also compared to relevant factors concerning their associations with various AEs. Methods Among 982 men who had RALP at Oslo University Hospital, Radiumhospitalet between 2005 and 2010, 79% responded to a mailed questionnaire in 2011. They rated AEs by completing the EPIC-26 questionnaire, and neuroticism on the Eysenck Personality Questionnaire (EPQ). Men with < 1 year’s follow-up, treatment failure, and incomplete EPQ responses were omitted, leaving 524 men for analysis. The EPQ responses were dichotomized into low and high level of neuroticism. Stepwise multivariate linear regression analyses were used for examination of associations with the EPIC-26 domain scores. Results High neuroticism was reported by 20% (95% CI 17–23%) of the patients. On the EPIC-26 dimensions men with high neuroticism had significantly lower mean scores than men with low neuroticism. Most of these between-group differences were clinically significant. In multivariate regression analyses, high neuroticism contributed significantly to all EPIC-26 domains. Conclusion Increased levels of AEs after RALP are significantly associated with high neuroticism. A short screening test should be added to the current EPIC-26 instrument to identify patients with high neuroticism. In these patients, pre-operative counseling should take into account their risk of increased AE experiences.

• Dybvik, Eva Hansen; Furnes, Ove; Havelin, Leif Ivar; Fosså, Sophie Dorothea; Trovik, Clement & Lie, Stein Atle (2020). A prospective study on cancer risk after total hip replacements for 41,402 patients linked to the Cancer registry of Norway. BMC Musculoskeletal Disorders.  ISSN 1471-2474.  21, s 1- 8 . doi: 10.1186/s12891-020-03605-7 Full text in Research Archive.
• Fosså, Sophie Dorothea; Aas, Kirsti; Muller, Christoph Rainer; Jerm, Marianne Brenn; Tandstad, Torgrim; Lilleby, Wolfgang; Kvåle, Rune; Gulbrandsen, Johanne; Haug, Erik Skaaheim & Myklebust, Tor Åge (2020). Definitive radiotherapy for prostate cancer in Norway 2006-2015: Temporal trends, performance and survival. Radiotherapy and Oncology.  ISSN 0167-8140.  155, s 33- 41 . doi: 10.1016/j.radonc.2020.10.022 Show summary

  Background More studies are needed to document nation-wide use and effectiveness of curative definitive radiotherapy (Def-RT) in the treatment of prostate cancer (PCa). Patients and methods For 38,960 men diagnosed with PCa without distant metastases from 2006 to 2015 data from the Norwegian Prostate Cancer Registry and a national radiotherapy database (NoRadBase) was analyzed. Overall survival and PCa-specific mortality were described comparing EQD-2 < 74 Gy (“low-dose”) with EQD-2 ≥ 74 Gy (“escalated dose”). Results Use of Def-RT decreased (27–24%) whereas the proportion of radical prostatectomies (RPs) increased (31–38%). In high-risk patients the use of RP doubled (18–36%), while the proportion of Def-RT remained stable (about 35%). Before 2010, almost a quarter of patients received low-dose Def-RT with gradual increase of escalated Def-RT thereafter. Escalated Def-RT was associated with significantly more favorable 10-year PCa-specific mortality (4.4% [95% CI: 2.7–10.7%]) than observed after low-dose Def- RT (8.8% [95% CI: 6.2–9.8%), with the most beneficial effects in high-risk patients. Our analyses indicated the need to expand the NoRadBase by consensus-based quality measures. Conclusion In this nationwide cohort, the overall use of Def-RT decreased slightly. In high-risk patients the provision of Def-RT remained stable and was accompanied by doubling of patients with RP and reduction of a “no curative treatment” strategy. Escalated dose Def-RT significantly reduced 10-year PCa-specific mortality compared to low-dose Def-RT. Aiming for cancer care equity national radiotherapy registries for PCa should regularly monitor data based on consensus-based quality measures enabling feedback to the responsible hospitals.

• Fosså, Sophie Dorothea; Dahl, Alv A; Myklebust, Tor Åge; Kiserud, Cecilie E.; Nome, Ragnhild Veline; Klepp, Olbjørn; Brydøy, Marianne & Haugnes, Hege Sagstuen (2020). Risk of positive selection bias in longitudinal surveys among cancer survivors: Lessons learnt from the national Norwegian Testicular Cancer Survivor Study. Cancer Epidemiology.  ISSN 1877-7821.  67:101774, s 1- 7 . doi: 10.1016/j.canep.2020.101744
• Gullestad, Hans Petter; Haugen, Gro S. & Fosså, Sophie Dorothea (2020). Late arm and shoulder problems after axillary therapeutic lymph node dissection in patients with melanoma. Journal of Plastic Surgery and Hand Surgery.  ISSN 2000-656X. . doi: 10.1080/2000656X.2020.1842746
• Hellesnes, Ragnhild; Myklebust, Tor Åge; Bremnes, Roy M.; Karlsdottir, Åsa; Kvammen, Øivind; Negaard, Helene Francisca Stigter; Tandstad, Torgrim; Wilsgaard, Tom; Fosså, Sophie Dorothea & Haugnes, Hege Sagstuen (2020). Metachronous Contralateral Testicular Cancer in the Cisplatin Era: A Population-Based Cohort Study. Journal of Clinical Oncology.  ISSN 0732-183X.  39(4), s 308- 318 . doi: 10.1200/jco.20.02713 Full text in Research Archive.
• Kerns, Sarah L.; Fung, Chunkit; Fosså, Sophie Dorothea; Dinh, Paul C.; Monahan, Patrick; Sesso, Howard D.; Frisina, Robert D.; Feldman, Darren R; Hamilton, Robert J.; Vaughn, David; Martin, Neil; Huddart, Robert; Kollmannsberger, Christian; Sahasrabudhe, Deepak; Ardeshir-Rouhani-Fard, Shirin; Einhorn, Lawrence & Travis, Lois B. (2020). Relationship of cisplatin-related adverse health outcomes with disability and unemployment among testicular cancer survivors. JNCI Cancer Spectrum.  ISSN 2515-5091.  4:pkaa022(4), s 1- 13 . doi: 10.1093/jncics/pkaa022 Show summary

  Abstract Background Few data exist on the relationship of cisplatin-related adverse health outcomes (AHOs) with disability, unemployment, and self-reported health (SRH) among testicular cancer survivors (TCS). Methods A total of 1815 TCS at least 1 year postchemotherapy underwent clinical examination and completed questionnaires. Treatment data were abstracted from medical records. A cumulative burden of morbidity score (CBMPt) encompassed the number and severity of platinum-related AHOs (peripheral sensory neuropathy [PSN], hearing loss, tinnitus, renal disease). Multivariable regression assessed the association of AHOs and CBMPt with employment status and SRH, adjusting for sociodemographic and clinical characteristics. Unemployment was compared with a male normative population of similar age, race, and ethnicity. Results Almost 1 in 10 TCS was out of work (2.4%, disability leave; 6.8%, unemployed) at a median age of 37 years (median follow-up = 4 years). PSN (odds ratio [OR] = 2.89, 95% confidence interval [CI] = 1.01 to 8.26, grade 3 vs 0, P = .048), renal dysfunction defined by estimated glomerular filtration rate (OR = 12.1, 95% CI = 2.06 to 70.8, grade 2 vs 0, P = .01), pain (OR = 10.6, 95% CI = 4.40 to 25.40, grade 2 or 3 vs 0, P < .001), and CBMPt (OR = 1.46, 95% CI = 1.03 to 2.08, P = .03) were associated with disability leave; pain strongly correlated with PSN (r2 = 0.40, P < .001). Statistically significantly higher percentages of TCS were unemployed vs population norms (age-adjusted OR = 2.67, 95% CI = 2.49 to 3.02, P < .001). PSN (OR = 2.44, 95% CI = 1.28 to 4.62, grade 3 vs 0, P = .006), patient-reported hearing loss (OR = 1.82, 95% CI = 1.04 to 3.17, grade 2 or 3 vs 0, P = .04), and pain (OR = 3.75, 95% CI = 2.06 to 6.81, grade 2 or 3 vs 0, P < .001) were associated with unemployment. Increasing severity of most cisplatin-related AHOs and pain were associated with statistically significantly worse SRH. Conclusions Our findings have important implications regarding treatment-associated productivity losses and socioeconomic costs in this young population. Survivorship care strategies should include inquiries about disability and unemployment status, with efforts made to assist affected TCS in returning to the workforce.

• Mellblom, Anneli; Kiserud, Cecilie E.; Rueegg, Corina Silvia; Ruud, Ellen; Loge, Jon Håvard; Fosså, Sophie Dorothea & Lie, Hanne Cathrine (2020). Self-reported late effects and long-term follow-up care among 1889 long-term Norwegian Childhood, Adolescent, and Young Adult Cancer Survivors (the NOR-CAYACS study). Supportive Care in Cancer.  ISSN 0941-4355.  s 1- 11 . doi: 10.1007/s00520-020-05790-6 Full text in Research Archive.
• Milano, Michael T.; Dinh, Paul C.; Yang, Hongmei; Zaid, Mohammad Abu; Fosså, Sophie Dorothea; Feldman, Darren R.; Monahan, Patrick O.; Travis, Lois B. & Fung, Chunkit (2020). Solid and Hematologic Neoplasms After Testicular Cancer: A US Population-Based Study of 24 900 Survivors. JNCI Cancer Spectrum.  ISSN 2515-5091.  4(3) . doi: 10.1093/jncics/pkaa017 Show summary

  Abstract Background No large US population-based study focusing on recent decades, to our knowledge, has comprehensively examined risks of second malignant solid and hematological neoplasms (solid-SMN and heme-SMN) after testicular cancer (TC), taking into account initial therapy and histological type. Methods Standardized incidence ratios (SIR) vs the general population and 95% confidence intervals (CI) for solid-SMN and heme-SMN were calculated for 24 900 TC survivors (TCS) reported to the National Cancer Institute’s Surveillance, Epidemiology, and End Results registries (1973–2014). All statistical tests were two-sided. Results The median age at TC diagnosis was 33 years. Initial management comprised chemotherapy (n = 6340), radiotherapy (n = 9058), or surgery alone (n = 8995). During 372 709 person-years of follow-up (mean = 15 years), 1625 TCS developed solid-SMN and 228 (107 lymphomas, 92 leukemias, 29 plasma cell dyscrasias) developed heme-SMN. Solid-SMN risk was increased 1.06-fold (95% CI = 1.01 to 1.12), with elevated risks following radiotherapy (SIR = 1.13, 95% CI = 1.06 to 1.21) and chemotherapy (SIR = 1.36, 95% CI = 1.12 to 1.41) but not surgery alone (SIR = 0.83, 95% CI = 0.75 to 0.92). Corresponding risks for seminoma were 1.13 (95% CI = 1.06 to 1.21), 1.28 (95% CI = 1.02 to 1.58), and 0.87 (95% CI = 0.74 to 1.01) and for nonseminoma were 1.05 (95% CI = 0.67 to 1.56), 1.25 (95% CI = 1.08 to 1.43), and 0.80 (95% CI = 0.70 to 0.92), respectively. Thirty-year cumulative incidences of solid-SMN after radiotherapy, chemotherapy, and surgery alone were 16.9% (95% CI = 15.7% to 18.1%), 10.1% (95% CI = 8.8% to 11.5%), and 8.8% (95% CI = 7.8% to 9.9%), respectively (P < .0001). Increased leukemia risks after chemotherapy (SIR = 2.68, 95% CI = 1.70 to 4.01) were driven by statistically significant sevenfold excesses of acute myeloid leukemia 1 to 10 years after TC diagnosis. Risks for lymphoma and plasma cell dyscrasias were not elevated. Conclusions We report statistically significant excesses of solid-SMN affecting 1 in 6 TCS 30 years after radiotherapy, and 2.7-fold risks of leukemias after chemotherapy, mostly acute myeloid leukemia. Efforts to minimize chemotherapy and radiotherapy exposures for TC should continue. TCS should be counseled about cancer prevention and screening.

• Nome, Ragnhild Veline; Småstuen, Milada Cvancarova; Bjøro, Trine; Kiserud, Cecilie E. & Fosså, Sophie Dorothea (2020). Longitudinal kidney function outcome in aging testicular cancer survivors. Acta Oncologica.  ISSN 0284-186X.  59:4, s 467- 474 . doi: 10.1080/0284186X.2020.1724328 Full text in Research Archive.
• Ryalen, Pål Christie; Stensrud, Mats Julius; Fosså, Sophie Dorothea & Røysland, Kjetil (2020). Causal inference in continuous time: an example on prostate cancer therapy. Biostatistics.  ISSN 1465-4644.  21(1), s 172- 185 . doi: 10.1093/biostatistics/kxy036 Full text in Research Archive.
• Skalleberg, Jakob Rasmussen; Småstuen, Milada Cvancarova; Oldenburg, Jan; Osnes, Terje; Fosså, Sophie Dorothea & Bunne, Bodil Iris Marie (2020). The relationship between cisplatin-related and age-related hearing loss during an extended follow-up. The Laryngoscope.  ISSN 0023-852X.  130(9), s E515- E521 . doi: 10.1002/lary.28543
• Stewart, Robert; Fosså, Sophie Dorothea; Hotopf, Matthew & Mykletun, Arnstein (2020). Extent of disease at first cancer presentation and previous anxiety and depressive symptoms: The HUNT study. British Journal of Psychiatry.  ISSN 0007-1250.  217(2), s 427- 433 . doi: 10.1192/bjp.2019.211
• Thorsen, Lene; Haugnes, Hege Sagstuen; Fosså, Sophie Dorothea; Brydøy, Marianne; Tandstad, Torgrim; Wisløff, Torbjørn; Gjerset, Gunhild Maria; Edvardsen, Elisabeth; Larsen, Karl-Otto; Sandset, Per Morten; Henriksson, Carola; Raastad, Truls & Negaard, Helene Francisca Stigter (2020). Thromboembolic events after high-intensity training duringcisplatin-based chemotherapy for testicular cancer: Casereports and review of the literature. International Journal of Cancer.  ISSN 0020-7136.  147(11), s 3189- 3198 . doi: 10.1002/ijc.33151 Full text in Research Archive. Show summary

  The randomized “Testicular cancer and Aerobic and Strength Training trial” (TAST‐trial) aimed to evaluate the effect of high‐intensity interval training (HIIT) on cardiorespiratory fitness during cisplatin‐based chemotherapy (CBCT) for testicular cancer (TC). Here, we report on an unexpected high number of thromboembolic (TE) events among patients randomized to the intervention arm, and on a review of the literature on TE events in TC patients undergoing CBCT. Patients aged 18 to 60 years with a diagnosis of metastatic germ cell TC, planned for 3 to 4 CBCT cycles, were randomized to a 9 to 12 weeks exercise intervention, or to a single lifestyle counseling session. The exercise intervention included two weekly HIIT sessions, each with 2 to 4 intervals of 2 to 4 minutes at 85% to 95% of peak heart rate. The study was prematurely discontinued after inclusion of 19 of the planned 94 patients, with nine patients randomized to the intervention arm and 10 to the control arm. Three patients in the intervention arm developed TE complications; two with pulmonary embolism and one with myocardial infarction. All three patients had clinical stage IIA TC. No TE complications were observed among patients in the control arm. Our observations indicate that high‐intensity aerobic training during CBCT might increase the risk of TE events in TC patients, leading to premature closure of the TAST‐trial.

• Vatne, Kari; Fosså, Sophie Dorothea; Dahl, Alv A; Myklebust, Tor Åge; Smeland, Sigbjørn & Stensvold, Andreas (2020). Prostatectomy with or without post-operative radiotherapy: long-term adverse effects and quality of life. Scandinavian Journal of Urology.  ISSN 2168-1805.  s 1- 8 . doi: 10.1080/21681805.2020.1854343 Full text in Research Archive.
• Bøhn, Synne-Kristin Hoffart; Thorsen, Lene; Kiserud, Cecilie E.; Fosså, Sophie Dorothea; Lie, Hanne Cathrine; Loge, Jon Håvard; Wisløff, Torbjørn; Haugnes, Hege Sagstuen & Reinertsen, Kristin Valborg (2019). Chronic fatigue and associated factors among long-term survivors of cancers in young adulthood. Acta Oncologica.  ISSN 0284-186X.  58(5), s 753- 762 . doi: 10.1080/0284186X.2018.1557344 Show summary

  Background: Chronic fatigue (CF) is scarcely explored among young adult cancer survivors (YACSs), and more knowledge is needed to develop targeted interventions for YACSs with CF. The present study aimed to investigate the prevalence of CF and associated factors in YACSs. Also, the change of fatigue with time was explored. Material and methods: The present cross-sectional study is part of a nation-wide population based survey of Norwegian survivors of cancer in childhood, adolescence, and young adulthood (The NOR-CAYACS study).YACSs diagnosed at the age of 19–39 years with breast cancer stage ≤ III (BC), colorectal cancer (CRC), non-Hodgkin lymphoma (NHL), acute lymphoblastic leukemia, or non-metastatic malignant melanoma (MM) were included 5–30 years after diagnosis. Survivors of MM treated with limited surgery were included as a reference group. CF was assessed by the Fatigue Questionnaire. Logistic regression analyses were performed to identify factors associated with CF. Results: In total, 1488 survivors completed the questionnaire (a response rate of 42%), of which 1088 were eligible for the present study. Overall, 25% reported CF. CF was significantly more prevalent among survivors of BC (29%) (p < .001), CRC (29%) (p = .001) and NHL (27%) (p = .003) than among survivors of MM (15%). CF was associated with systemic treatment combined with surgery and/or radiotherapy (p = .018), comorbidity (p = .038), pain (p = .002), numbness in hands/feet (p = .046), and depressive symptoms (p < .001) in the multivariable model. Among survivors with CF, 60% reported that they had been tired since cancer treatment, and among these, 65% reported worsening or no change of fatigue with time. Conclusion: One of four YACSs reported CF 15 years from diagnosis (mean). CF was associated with several possibly treatable factors. Health professionals involved in the follow-up of YACSs should have knowledge of CF and approaches to manage it.

• Gjerset, Gunhild Maria; Kiserud, Cecilie E.; Loge, Jon Håvard; Fosså, Sophie Dorothea; Wisløff, Torbjørn; Gudbergsson, Sævar Berg; Oldervoll, Line Merethe & Thorsen, Lene (2019). Changes in fatigue, health-related quality of life and physical activity after a one-week educational program for cancer survivors. Acta Oncologica.  ISSN 0284-186X.  58(5), s 682- 689 . doi: 10.1080/0284186X.2018.1562210 Full text in Research Archive.
• Aksnessæther, Bjørg Yksnøy; Myklebust, Tor Åge; Solberg, Arne; Klepp, Olbjørn; Skovlund, Eva; Hoff, Solveig Roth; Fosså, Sophie Dorothea; Widmark, Anders & Lund, Jo-Åsmund (2019). Second Cancers in Patients With Locally Advanced Prostate Cancer Randomized to Lifelong Endocrine Treatment With or Without Radical Radiation Therapy: Long-Term Follow-up of the Scandinavian Prostate Cancer Group-7 Trial. International Journal of Radiation Oncology, Biology, Physics.  ISSN 0360-3016.  106(4), s 706- 714 . doi: 10.1016/j.ijrobp.2019.11.027 Full text in Research Archive.
• Bucher-Johannessen, Cecilie; Page, Christian Magnus; Haugen, Trine B.; Wojewodzic, Marcin; Fosså, Sophie Dorothea; Grotmol, Tom; Haugnes, Hege Sagstuen & Rounge, Trine Ballestad (2019). Cisplatin treatment of testicular cancer patients introduces long-term changes in the epigenome. Clinical Epigenetics.  ISSN 1868-7075.  11:179, s 1- 13 . doi: 10.1186/s13148-019-0764-4 Full text in Research Archive.
• Dahl, Alv A; Fosså, Sophie Dorothea; Lie, Hanne Cathrine; Loge, Jon Håvard; Reinertsen, Kristin Valborg; Ruud, Ellen & Kiserud, Cecilie E. (2019). Employment Status and Work Ability in Long-Term Young Adult Cancer Survivors. Journal of Adolescent and Young Adult Oncology.  ISSN 2156-5333.  8(3), s 304- 311 . doi: 10.1089/jayao.2018.0109 Full text in Research Archive.
• El Charif, Omar; Mapes, Brandon; Trendowski, Matthew R.; Wheeler, Heather E.; Wing, Claudia; Dinh, Paul C.; Frisina, Robert D.; Feldman, Darren R.; Hamilton, Robert J.; Vaughn, David J.; Fung, Chunkit; Kollmannsberger, Christian; Mushiroda, Taisei; Kubo, Michiaki; Gamazon, Eric R.; Cox, Nancy J.; Huddart, Robert; Ardeshir-Rouhani-Fard, Shirin; Monahan, Patrick; Fosså, Sophie Dorothea; Einhorn, Lawrence H.; Travis, Lois B. & Dolan, M. Eileen (2019). Clinical and Genome-wide Analysis of Cisplatin-induced Tinnitus Implicates Novel Ototoxic Mechanisms. Clinical Cancer Research.  ISSN 1078-0432.  25(13), s 4104- 4116 . doi: 10.1158/1078-0432.CCR-18-3179
• Fosså, Sophie Dorothea; Beyer, Bud; Dahl, Alv A; Aas, Kirsti; Eri, Lars Magne; Kvan, Espen; Falk, Ragnhild Sørum; Graefen, Markus; Huland, Hartwig & Berge, Viktor (2019). Improved patient-reported functional outcomes after nerve-sparing radical prostatectomy by using NeuroSAFE technique. Scandinavian Journal of Urology.  ISSN 2168-1805.  s 1- 7 . doi: 10.1080/21681805.2019.1693625 Full text in Research Archive.
• Fung, Chunkit; Dinh, Paul C.; Fosså, Sophie Dorothea & Travis, Lois B. (2019). Testicular cancer survivorship. The Journal of the National Comprehensive Cancer Network.  ISSN 1540-1405.  17(12), s 1557- 1568 . doi: 10.6004/jnccn.2019.7369
• Hellesnes, Ragnhild; Kvammen, Øivind; Myklebust, Tor Åge; Bremnes, Roy M.; Karlsdottir, Åsa; Negaard, Helene Francisca Stigter; Tandstad, Torgrim; Wilsgaard, Tom; Fosså, Sophie Dorothea & Haugnes, Hege Sagstuen (2019). Continuing increased risk of second cancer in long-term testicular cancer survivors after treatment in the cisplatin era. International Journal of Cancer.  ISSN 0020-7136.  147(1), s 21- 32 . doi: 10.1002/ijc.32704 Full text in Research Archive.
• Kvammen, Øivind; Myklebust, Tor Åge; Solberg, Arne; Møller, Bjørn; Klepp, Olbjørn; Fosså, Sophie Dorothea & Tandstad, Torgrim (2019). Causes of inferior relative survival after testicular germ cell tumor diagnosed 1953–2015: A population-based prospective cohort study. PLOS ONE.  ISSN 1932-6203.  14:e0225942(12), s 1- 15 . doi: 10.1371/journal.pone.0225942 Full text in Research Archive.
• Kvåle, Rune; Myklebust, Tor Åge; Fosså, Sophie Dorothea; Aas, Kirsti; Ekanger, Christian; Helle, Svein Inge; Honore, Alfred & Møller, Bjørn (2019). Impact of positive surgical margins on secondary treatment, palliative radiotherapy and prostate cancer‐specific mortality. A population‐based study of 13 198 patients. The Prostate.  ISSN 0270-4137.  79(16), s 1852- 1860 . doi: 10.1002/pros.23911 Full text in Research Archive. Show summary

  Background: The results of studies evaluating the impact of positive surgical margins on prostate cancer‐specific mortality have been inconsistent. We, therefore, evaluated the impact of surgical margin status on subsequent secondary treatment, palliative radiotherapy, and prostate cancer‐specific mortality. Methods A total of 14 837 men treated with radical prostatectomy (RP) during the period 2001 to 2015 were identified from the Cancer Registry of Norway. Of those, 13 198 (89%) patients had complete data on the preoperative prostate‐specific antigen level, pathological T‐category, Gleason score in the prostatectomy specimen, and margin status. Multivariable Cox proportional hazards models were used to evaluate the risk, and flexible parametric models for the cumulative incidence were fitted to predict the probabilities of secondary treatment (salvage radiotherapy or prophylactic breast radiation), palliative radiotherapy, and prostate cancer‐specific mortality. Results After a median follow‐up time of 5.2 years (3591 patients with ≥8 years of follow‐up), positive surgical margins (PSMs) were independently predictive of secondary treatment (hazard ratio [HR] = 2.43, 95% confidence interval [CI] = 2.21‐2.66) and palliative radiotherapy (HR = 1.45, 95% CI = 1.03‐2.05). After 10 years, the absolute increased risk for palliative radiotherapy in patients with PSMs after RP varied between 0.1% in pT2 tumors with a Gleason score of 6, to 12% for pT3b tumors with a Gleason score of 9 to 10. PSMs were not independently associated with prostate cancer‐specific mortality (HR = 1.14, 95% CI = 0.82‐1.59). Conclusion PSMs were associated with increased application of secondary treatment and palliative radiotherapy but were not predictive of prostate cancer‐specific mortality. As the use of palliative radiotherapy was only marginally increased in patients with PSMs and the lowest‐risk disease characteristics, avoiding PSMs may be of greatest prognostic relevance in patients with higher‐risk disease characteristics.

• Lie, Hanne Cathrine; Rueegg, Corina Silvia; Fosså, Sophie Dorothea; Loge, Jon Håvard; Ruud, Ellen & Kiserud, Cecilie E. (2019). Limited evidence of non-response bias despite modest response rate in a nationwide survey of long-term cancer survivors?results from the NOR-CAYACS study. Journal of cancer survivorship.  ISSN 1932-2259.  13(3), s 353- 363 . doi: 10.1007/s11764-019-00757-x Full text in Research Archive.
• Solheim, Olesya; Skalleberg, Jakob Rasmussen; Warncke, Torhild; Ørstavik, Kristin; Tropé, Claes Gøran & Fosså, Sophie Dorothea (2019). Long‐term neurotoxicity and Raynaud's phenomenon in patients treated with cisplatin‐based chemotherapy for malignant ovarian germ cell tumor. Acta Obstetricia et Gynecologica Scandinavica.  ISSN 0001-6349.  98(2), s 240- 249 . doi: 10.1111/aogs.13477 Full text in Research Archive. Show summary

  Introduction The aim was to evaluate “overall neuropathy”, defined as peripheral paresthesia and Raynaud's phenomenon, in long‐term survivors of malignant ovarian germ cell tumors (MOGCTs) treated with cisplatin‐based chemotherapy (CBCT). Material and methods Ninety‐three MOGCT survivors recorded in Norway in 1980‐2009 (median follow up: 15 years) were included in this analysis. Forty‐nine received CBCT (CBCT group) and 44 received other or no chemotherapy (non‐CBCT group). Applying the scale for chemotherapy‐induced neurotoxicity, the prevalence of overall neuropathy (ie score >1 on a 0‐3 scale) was compared between the two groups. Forty women from the CBCT group also underwent neurophysiological and neurological examinations; results from the neurological examination were graded according to the National Cancer Institute‐Common Terminology Criteria for Adverse Effects version 4 (NCI‐CTCAE scale v4). These women were then categorized into subgroups of low (≤3 cycles of CBCT, n = 23) and high CBCT (≥4 cycles of CBCT, n = 17). Results Twenty‐eight (57%) women from the CBCT group reported overall neuropathy, compared with 20 (45%) in the non‐CBCT group (P = .06). Of the 40 MOGCT survivors in the CBCT group who underwent neurophysiological and neurological examinations, 14 (35%) showed NCI‐CTCAE grade ≥1 signs or symptoms of peripheral neuropathy. Pathological findings of NCI‐CTCAE grade 2 or 3 signs or symptoms were found in four survivors (10%) from the high CBCT subgroup, all of whom also showed objective signs of neuropathy. Conclusions Though about half of our MOGCT survivors reported overall neuropathy after CBCT, more severe pathological neurological/neurophysiological findings that impacted daily living were recorded in only 10% of them. Our observations of a similar prevalence of self‐reported overall neuropathy in the CBCT and non‐CBCT group, combined with limited objective neurological findings, warrant further study to increase the understanding of the specific pathophysiological pathways of long‐term CBCT‐induced neuropathy.

• Storås, Anne Marie Holck; Sanda, Martin G.; Garin, Olatz; Chang, Peter; Patil, Dattatraya; Crociani, Catrina; Suarez, Jose Francisco; Småstuen, Milada Cvancarova; Loge, Jon Håvard & Fosså, Sophie Dorothea (2019). A prospective study of patient reported urinary incontinence among American, Norwegian and Spanish men 1 year after prostatectomy. Asian Journal of Urology (AJU).  ISSN 2214-3882.  s 1- 9 . doi: 10.1016/j.ajur.2019.08.001 Full text in Research Archive.
• Trendowski, Matthew R.; El-Charif, Omar; El Charif, Omar; Ratain, Mark J.; Monahan, Patrick; Mu, Zepeng; Wheeler, Heather E.; Dinh, Paul C.; Feldman, Darren R.; Ardeshir-Rouhani-Fard, Shirin; Hamilton, Robert J.; Vaughn, David J.; Fung, Chunkit; Kollmannsberger, Christian; Mushiroda, Taisei; Kubo, Michiaki; Hannigan, Robyn; Strathmann, Frederick; Einhorn, Lawrence H.; Fosså, Sophie Dorothea; Travis, Lois B. & Dolan, M. Eileen (2019). Clinical and genome-wide analysis of serum platinum levels after cisplatin-based chemotherapy. Clinical Cancer Research.  ISSN 1078-0432.  25(19), s 5913- 5924 . doi: 10.1158/1078-0432.CCR-19-0113
• Zaid, Mohammad Abu; Dinh, Paul C.; Monahan, Patrick O.; Fung, Chunkit; El-Charif, Omar; Feldman, Darren R; Hamilton, Robert J; Vaughn, David J; Beard, Clair J.; Cook, Ryan; Althouse, Sandra; Ardeshir-Rouhani-Fard, Shirin; Sesso, Howard D; Huddart, Robert; Mushiroda, Taisei; Kubo, Michiaki; Eileen Dolan, M; Einhorn, Lawrence H; Fosså, Sophie Dorothea & Travis, Lois B (2019). Adverse health outcomes in relationship to hypogonadism after chemotherapy: A multicenter study of testicular cancer survivors. The Journal of the National Comprehensive Cancer Network.  ISSN 1540-1405.  17(5), s 459- 468 . doi: 10.6004/jnccn.2018.7109
• Bøhn, Synne-Kristin Hoffart; Fosså, Sophie Dorothea; Wisløff, Torbjørn & Thorsen, Lene (2018). Physical activity and associations with treatment-induced adverse effects among prostate cancer patients. Supportive Care in Cancer.  ISSN 0941-4355.  27(3), s 1001- 1011 . doi: 10.1007/s00520-018-4389-5
• Aas, Kirsti; Fosså, Sophie Dorothea; Kvåle, Rune; Møller, Bjørn; Myklebust, Tor Åge; Vlatkovic, Ljiljana; Müller, Stig & Berge, Viktor (2018). Is time from diagnosis to radical prostatectomy associated with oncological outcomes?. World Journal of Urology.  ISSN 0724-4983.  37(8), s 1571- 1580 . doi: 10.1007/s00345-018-2570-6
• Ávila, Mónica; Patel, Laila; López, Silvia; Cortés-Sanabria, Laura; Garin, Olatz; Pont, Àngels; Ferrer, Ferran; Boladeras, Ana; Zamora, Victor; Fosså, Sophie Dorothea; Storås, Anne Marie Holck; Sanda, Martin; Serra-Sutton, Vicky & Ferrer, Montse (2018). Patient-reported outcomes after treatment for clinically localized prostate cancer: A systematic review and meta-analysis. Cancer Treatment Reviews.  ISSN 0305-7372.  66, s 23- 44 . doi: 10.1016/j.ctrv.2018.03.005
• Byrne, Julianne; Grabow, Desiree; Campbell, Helen; O'Brien, Kylie; Bielack, Stefan; am Zehnhoff-Dinnesen, Antoinette; Calaminus, Gabriele; Kremer, Leontien; Langer, Thorsten; van den Heuvel-Eibrink, Marry M.; van Dulmen-den Broeder, Eline; Baust, Katja; Bautz, Andrea; Beck, Jörn D.; Berger, Claire; Binder, Harald; Borgmann-Staudt, Anja; Broer, Linda; Cario, Holger; Casagranda, Leonie; Clemens, Eva; Deuster, Dirk; de Vries, Andrica; Dirksen, Uta; Falck Winther, Jeanette; Fosså, Sophie Dorothea; Font-Gonzalez, Anna; Grandage, Victoria; Haupt, Riccardo; Hecker-Nolting, Stefanie; Hjorth, Lars; Kaiser, Melanie; Kenborg, Line; Kepak, Tomas; Kepakova, Katerina; Knudsen, Lisbeth E; Krawczuk-Rybak, Maryna; Kruseova, Jarmila; Kuehni, Claudia E.; Kunstreich, Marina; Kuonen, Rahel; Lackner, Herwig; Leiper, Alison; Loeffen, Erik A.H.; Luks, Ales; Modan-Moses, Dalit; Mulder, Renee; Parfitt, Ross; Paul, Norbert W.; Ranft, Andreas; Ruud, Ellen; Schilling, Ralph; Spix, Claudia; Stefanowicz, Joanna; Strauβ, Gabriele; Uitterlinden, André G.; van den Berg, Marleen; van der Kooi, Anne-Lotte; van Dijk, Marloes; van Leeuwen, Flora; Zolk, Oliver; Zoller, Daniela & Kaatsch, Peter (2018). PanCareLIFE: The scientific basis for a European project to improve long-term care regarding fertility, ototoxicity and health-related quality of life after cancer occurring among children and adolescents. European Journal of Cancer.  ISSN 0959-8049.  103, s 227- 237 . doi: 10.1016/j.ejca.2018.08.007
• Chen, Haitao; Ewing, Charles M; Zheng, Sigun; Grindedal, Eli Marie; Cooney, Kathleen A.; Wiley, Kathleen E.; Djurovic, Srdjan; Andreassen, Ole Andreas; Axcrona, Karol; Mills, Ian Geoffrey; Xu, Jianfeng; Mæhle, Lovise Olaug; Fosså, Sophie Dorothea & Isaacs, William B. (2018). Genetic factors influencing prostate cancer risk in Norwegian men. The Prostate.  ISSN 0270-4137.  78(3), s 186- 192 . doi: 10.1002/pros.23453 Full text in Research Archive.
• Feldman, Darren R.; Ardeshir-Rouhani-Fard, Shirin; Monahan, Patrick O.; Sesso, Howard D.; Fung, Chunkit; Williams, Annalynn M.; Hamilton, Robert J.; Vaughn, David J.; Beard, Clair J.; Cook, Ryan; Zaid, Mohammad Abu; Lipshultz, Steven E.; Einhorn, Lawrence H.; Oeffinger, Kevin Charles; Travis, Lois B. & Fosså, Sophie Dorothea (2018). Predicting cardiovascular disease among testicular cancer survivors after modern cisplatin-based chemotherapy: Application of the Framingham Risk Score. Clinical Genitourinary Cancer.  ISSN 1558-7673.  16(4), s e761- e769 . doi: 10.1016/j.clgc.2018.01.011
• Fosså, Sophie Dorothea; Fung, Chunkit & Dahl, Alv A (2018). Late adverse outcomes after treatment of testicular cancer. Der Onkologe.  ISSN 0947-8965.  24, s 104- 109 . doi: 10.1007/s00761-018-0442-8
• Fung, Chunkit; Dinh, Paul; Ardeshir-Rouhani-Fard, Shirin; Schaffer, Kerry; Fosså, Sophie Dorothea & Travis, Lois B. (2018). Toxicities associated with cisplatin-based chemotherapy and radiotherapy in long-term testicular cancer survivors. Advances in Urology.  ISSN 1687-6369.  2018:8671832, s 1- 20 . doi: 10.1155/2018/8671832
• Haugnes, Hege Sagstuen; Stenklev, Niels Christian; Brydøy, Marianne; Dahl, Olav; Wilsgaard, Tom; Laukli, Einar & Fosså, Sophie Dorothea (2018). Hearing loss before and after cisplatin-based chemotherapy in testicular cancer survivors: a longitudinal study. Acta Oncologica.  ISSN 0284-186X.  57(8), s 1075- 1083 . doi: 10.1080/0284186X.2018.1433323
• Hjelle, Line Veronika; Gundersen, Per Ole Mobråten; Hellesnes, Ragnhild; Sprauten, Mette; Brydøy, Marianne; Tanstad, Torgrim; Wilsgaard, Tom; Fosså, Sophie Dorothea; Oldenburg, Jan; Bremnes, Roy M. & Haugnes, Hege Sagstuen (2018). Long-term serum platinum changes and their association with cisplatin-related late effects in testicular cancer survivors. Acta Oncologica.  ISSN 0284-186X.  57(10), s 1392- 1400 . doi: 10.1080/0284186X.2018.1473641
• Honecker, F; Aparicio, J; Berney, D; Beyer, J; Bokemeyer, C; Cathomas, R; Clarke, N.; Cohn-Cedermark, G; Daugaard, G; Dieckmann, KP; Fizazi, K; Fosså, Sophie Dorothea; Germa-Lluch, JR; Giannatempo, P; Gietema, JA; Gillessen, S; Haugnes, Hege Sagstuen; Heidenreich, A; Hemminki, K; Huddart, R; Jewett, MAS; Joly, F; Lauritsen, Jens; Lorch, A; Necchi, A; Nicolai, N; Oing, C; Oldenburg, Jan; Ondrus, D; Papachristofilou, A; Powles, T; Sohaib, A; Ståhl, Olof; Tandstad, T.; Toner, G & Horwich, A (2018). ESMO consensus conference on testicular germ cell cancer: Diagnosis, treatment and follow-up. Annals of Oncology.  ISSN 0923-7534.  29(8), s 1658- 1686 . doi: 10.1093/annonc/mdy217
• Kerns, Sarah L.; Fung, Chunkit; Monahan, Patrick O.; Ardeshir-Rouhani-Fard, Shirin; Abu Zaid, Mohammad I.; Williams, Annalynn M.; Stump, Timothy E.; Sesso, Howard D.; Feldman, Darren R.; Hamilton, Robert J.; Vaughn, David J.; Beard, Clair; Huddart, Robert A.; Kim, Jeri; Kollmannsberger, Christian; Sahasrabudhe, Deepak M.; Cook, Ryan; Fosså, Sophie Dorothea; Einhorn, Lawrence H. & Travis, Lois B. (2018). Cumulative burden of morbidity among testicular cancer survivors after standard cisplatin-based chemotherapy: A multi-institutional study. Journal of Clinical Oncology.  ISSN 0732-183X.  36(15), s 1505- 1512 . doi: 10.1200/JCO.2017.77.0735
• Parker, Christopher C.; Coleman, Robert Edward; Sartor, Oliver; Vogelzang, Nicholas J.; Bottomley, David; Heinrich, Daniel; Helle, Svein Inge; O'Sullivan, Joe M.; Fosså, Sophie Dorothea; Chodacki, Aleš; Wiechno, Paweł; Logue, John; Seke, Mihalj; Widmark, Anders; Johannessen, Dag Clement; Hoskin, Peter; James, Nicholas D.; Solberg, Arne; Syndikus, Isabel; Kliment, Jan; Wedel, Steffen; Böhmer, Sibylle; Dall'Oglio, Marcos; Franzén, Lars; Bruland, Øyvind; Petrenciuc, Oana; Staudacher, Karin; Li, Rui & Nilsson, Sten (2018). Three-year Safety of Radium-223 Dichloride in Patients with Castration-resistant Prostate Cancer and Symptomatic Bone Metastases from Phase 3 Randomized Alpharadin in Symptomatic Prostate Cancer Trial. European Urology.  ISSN 0302-2838.  73(3), s 353- 360 . doi: 10.1016/j.eururo.2017.06.021
• van den Berg, Marleen; van Dijk, Marloes; Byrne, Julianne; Campbell, Helen; Berger, Claire; Borgmann-Staudt, Anja; Calaminus, Gabriele; Dirksen, Uta; Winther, Jeanette F.; Fosså, Sophie Dorothea; Grabow, Desiree; Grandage, Victoria L.; van den Heuvel-Eibrink, Marry M.; Kaiser, Melanie; Kepák, Tomáš; Kremer, Leontien C.; Kruseova, Jarmilá; Kuehni, Claudia E.; Lambalk, Cornelis B.; van Leeuwen, Fllora E.; Leiper, Alison; Modan-Moses, Dalit; Morsellino, Vera; Spix, Claudia; Kaatsch, Peter & van Dulmen-den Broeder, Eline (2018). Fertility among female survivors of childhood, adolescent, and young adult cancer: Protocol for two pan-European studies (PanCareLIFE). Journal of Medical Internet Research.  ISSN 1438-8871.  20:e10824(9), s 1- 13 . doi: 10.2196/10824
• van der Kooi, Anne-Lotte; Clemens, Eva; Broer, Linda; Zolk, Oliver; Byrne, Julianne; Campbell, Helen; van den Berg, Marleen; Berger, Claire; Calaminus, Gabriele; Dirksen, Uta; Winther, Jeanette Falck; Fosså, Sophie Dorothea; Grabow, Desiree; Haupt, Riccardo; Kaiser, Melanie; Kepak, Tomas; Kremer, Leontien; Kruseova, Jarmila; Modan-Moses, Dalit; Ranft, Andreas; Spix, Claudia; Kaatsch, Peter; Laven, Joop S.E.; van Dulmen-den Broeder, Eline; Uitterlinden, André G. & van den Heuvel-Eibrink, Marry M. (2018). Genetic variation in gonadal impairment in female survivors of childhood cancer: a PanCareLIFE study protocol. BMC Cancer.  ISSN 1471-2407.  18(1), s 930 . doi: 10.1186/s12885-018-4834-3
• Wedde, Trude Baastad; Småstuen, Milada Cvancarova; Brabrand, Sigmund; Fosså, Sophie Dorothea; Kaasa, Stein; Tafjord, Gunnar; Russnes, Kjell Magne; Hellebust, Taran Paulsen & Lilleby, Wolfgang (2018). Ten-year survival after High-Dose-Rate Brachytherapy combined with External Beam Radiation Therapy in high-risk prostate cancer: A comparison with the Norwegian SPCG-7 cohort. Radiotherapy and Oncology.  ISSN 0167-8140.  s 1- 7 . doi: 10.1016/j.radonc.2018.10.013 Full text in Research Archive.
• Zaid, Mohammad Abu; Gathirua-Mwangi, Wambui G; Fung, Chunkit; Monahan, Patrick O.; El-Charif, Omar; Williams, Annalynn M; Feldman, Darren R; Hamilton, Robert J; Vaughn, David J; Beard, Clair J; Cook, Ryan; Althouse, Sandra; Ardeshir-Rouhani-Fard, Shirin; Dinh, Paul; Sesso, Howard D; Einhorn, Lawrence H; Fosså, Sophie Dorothea & Travis, Lois B (2018). Clinical and Genetic Risk Factors for Adverse Metabolic Outcomes in North American Testicular Cancer Survivors. The Journal of the National Comprehensive Cancer Network.  ISSN 1540-1405.  16(3), s 257- 265 . doi: 10.6004/jnccn.2017.7046
• Gjerset, Gunhild Maria; Loge, Jon Håvard; Kiserud, Cecilie E.; Fosså, Sophie Dorothea; Gudbergsson, Sævar Berg; Oldervoll, Line Merethe; Wisløff, Torbjørn & Thorsen, Lene (2017). Perceived needs for different components in a rehabilitation program among cancer survivors with chronic fatigue compared to survivors without chronic fatigue. Acta Oncologica.  ISSN 0284-186X.  56(2), s 245- 253 . doi: 10.1080/0284186X.2016.1266091 Full text in Research Archive.
• Thorsen, Lene; Kirkegaard, Camilla; Loge, Jon Håvard; Kiserud, Cecilie E.; Johansen, Merethe Lia; Gjerset, Gunhild Maria; Edvardsen, Elisabeth; Hamre, Hanne Mari; Andersen, Tone Ikdahl & Fosså, Sophie Dorothea (2017). Feasibility of a physical activity intervention during and shortly after chemotherapy for testicular cancer. BMC Research Notes.  ISSN 1756-0500.  10(214) . doi: 10.1186/s13104-017-2531-y Full text in Research Archive.
• Aas, Kirsti; Axcrona, Karol; Kvåle, Rune; Møller, Bjørn; Myklebust, Tor Åge; Axcrona, Ulrika; Berge, Viktor & Fosså, Sophie Dorothea (2017). Ten-year Mortality in Men With Nonmetastatic Prostate Cancer in Norway. Urology.  ISSN 0090-4295.  110, s 140- 147 . doi: 10.1016/j.urology.2017.07.048
• Axcrona, Karol; Nilsson, Rasmus; Brennhovd, Bjørn; Sørebø, Øystein; Fosså, Sophie Dorothea & Dahl, Alv A (2017). Psychometric properties of the expanded prostate cancer index composite - 26 instrument in a cohort of radical prostatectomy patients: theoretical and practical examinations. BMC Urology.  ISSN 1471-2490.  17(1) . doi: 10.1186/s12894-017-0302-7 Full text in Research Archive. Show summary

  Background Recently, the Expanded Prostate Cancer Index Composite 26-item version (EPIC-26) was recommended for the assessment of adverse effects after the treatment of prostate cancer without clear reasons. This decision encouraged us to review the questionnaire development from the UCLA Prostate Cancer Index (UCLA-PCI) to the EPIC-16 CP with a focus on psychometric properties. We also reviewed PubMed for papers concerning such properties of the EPIC-26 since 2012 (latest review in 2011). Finally, we examined the psychometric properties of the EPIC-26 in a sample of Norwegian males treated with robot-assisted laparoscopic prostatectomy (RALP). Methods This study used three methods: (1) Comparison of the content of the UCLA-PCI, EPIC-50, EPIC-26, and EPIC-16 CP; (2) Review of EPIC-26 and EPIC-16 CP papers in PubMed from 2012 to 2016, identifying papers reporting on the psychometric properties of these questionnaires; and (3) Psychometric examination of the EPIC-26 rating in 651 Norwegian men treated with RALP at a mean of 3.2 years post-surgery. Results The questionnaire development showed a significant increase in bother versus function items, and the EPIC-26 contains eight function and 18 bother items. Twelve papers concerning the EPIC-26 available on PubMed since 2012 support the psychometric properties of the EPIC-26. The Norwegian EPIC-26 findings supported the psychometric properties of the EPIC-26, but suggested six subdomains both by exploratory and confirmatory factor analyses. Conclusions In general our examinations supported the adequate psychometric properties of the EPIC-26, although the factor structure, construct and predictive validity of the instrument should be examined further.

• Dolan, M. Eileen; El Charif, Omar; Wheeler, Heather E.; Gamazon, Eric R.; Ardeshir-Rouhani-Fard, Shirin; Monahan, Patrick; Feldman, Darren R.; Hamilton, Robert J.; Vaughn, David J.; Beard, Clair J.; Fung, Chunkit; Kim, Jeri; Fosså, Sophie Dorothea; Hertz, Daniel L.; Mushiroda, Taisei; Kubo, Michiaki; Einhorn, Lawrence H.; Cox, Nancy J. & Travis, Lois B. (2017). Clinical and genome-wide analysis of cisplatin-induced peripheral neuropathy in survivors of adult-onset cancer. Clinical Cancer Research.  ISSN 1078-0432.  23(19), s 5757- 5768 . doi: 10.1158/1078-0432.CCR-16-3224
• Fung, Chunkit; Sesso, Howard D.; Williams, Annalynn M.; Kerns, Sarah L.; Monahan, Patrick; Zaid, Mohammad Abu; Feldman, Darren R.; Hamilton, Robert J.; Vaughn, David J.; Beard, Clair J.; Kollmannsberger, Christian K.; Cook, Ryan; Althouse, Sandra; Ardeshir-Rouhani-Fard, Shirin; Lipshultz, Steve E.; Einhorn, Lawrence H.; Fosså, Sophie Dorothea & Travis, Lois B. (2017). Multi-institutional assessment of adverse health outcomes among north American testicular cancer survivors after modern cisplatin-based chemotherapy. Journal of Clinical Oncology.  ISSN 0732-183X.  35(11), s 1211- 1222 . doi: 10.1200/JCO.2016.70.3108
• Gilbert, Ethel S.; Curtis, Rochelle E.; Hauptmann, Michael; Kleinerman, Ruth A.; Lynch, Charles F.; Stovall, Marilyn; Smith, Susan A.; Weathers, Rita; Andersson, Michael; Dores, Graça M.; Fraumeni, Joseph F.; Fosså, Sophie Dorothea; Hall, Per; Hodgson, David C.; Holowaty, Eric J.; Joensuu, Heikki; Johannessen, Tom Børge; Langmark, Frøydis Tonning; Kaijser, Magnus; Pukkala, Eero; Rajaraman, Preetha; Storm, Hans H.; Vaalavirta, Leila; van den Belt-Dusebout, Alexandra W.; Aleman, Berthe M.; Travis, Lois B.; Morton, Lindsay M. & van Leeuwen, Flora E. (2017). Stomach cancer following Hodgkin lymphoma, testicular cancer and cervical cancer: a pooled analysis of three international studies with a focus on radiation effects. Radiation Research.  ISSN 0033-7587.  187(2), s 186- 195 . doi: 10.1667/RR14453.1
• Grov, Ellen Karine; Fosså, Sophie Dorothea & Dahl, Alv A (2017). A controlled study of the influence of comorbidity on activities of daily living in elderly cancer survivors (the HUNT-3 survey).. Journal of Geriatric Oncology.  ISSN 1879-4068.  8(5), s 328- 335 . doi: 10.1016/j.jgo.2017.05.007 Show summary

  Objectives: To examine the influence of somatic comorbidity on Activity of Daily Living (ADL) problems in cancer survivors ≥70 years (ECSs) based on data from The Health Study of Nord-Trøndelag County (HUNT-3) 2006–08. Material andMethods: Among participants of the HUNT-3 survey, 599 ECSs had a diagnosis of one invasive cancer according to both The Cancer Registry of Norway and self-report. Three controls without cancer aged ≥70 years for each ECS were drawn from the HUNT-3 sample.We compared personal-ADL (P-ADL) and instrumental-ADL (I-ADL) problems for ECSs and differences between ADL problems for ECSs with and without comorbidity and controls with and without comorbidity. Results: The prevalence of P-ADL problems was 3.5% among ECSs and 2.9% among controls (p = 0.97) and for I-ADL 28.5% versus 21.4% (p = 0.01), respectively. In bivariate analyses where ECSs versus controls was the dependent variable, presence of I-ADL problems, higher age, being female, paired relationship, poor self-rated health, hospitalization last year, and low level of neuroticism were associated being ECSs. In multivariate analyses, these variables, except I-ADL-problems and paired relationship, remained significantly associated being ECSs. No significant differenceswere shown for P-ADL problemswhen comparing ECSs and controlswith comorbidity, and ECSswith andwithout comorbidity. ECSswith comorbidity reported significantlymore I-ADL-problems than controls with comorbidity, and ECSswith comorbidity had significantly more I-ADL-problems than ECSs without comorbidity. Conclusion: Our results reflect common factors found in ADL studies in the elderly population. Health personnel have to be particularly observant on I-ADL problems among female ECSs, and those reporting poor self-rated health or comorbidity.

• Holm, Henriette Veiby; Dahl, Alv A; Klepp, Olbjørn & Fosså, Sophie Dorothea (2017). Moderne behandling av prostatakreft med fjernmetastaser. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  137(11), s 803- 805 . doi: 10.4045/tidsskr.16.0265
• Jacobsen, Ellisiv Lærum; Bye, Asta; Aass, Nina Kathrine; Fosså, Sophie Dorothea; Grotmol, Kjersti Støen; Kaasa, Stein; Loge, Jon Håvard; Moum, Torbjørn Åge & Hjermstad, Marianne Jensen (2017). Norwegian reference values for the Short-Form Health Survey 36: development over time. Quality of Life Research.  ISSN 0962-9343.  s 1- 12 . doi: 10.1007/s11136-017-1684-4 Full text in Research Archive.
• Johannsdottir, Inga Marie; Hamre, Hanne Mari; Fosså, Sophie Dorothea; Loge, Jon Håvard; Drolsum, Liv; Lund, May-Brith; Nordsletten, Lars & Kiserud, Cecilie E. (2017). Adverse Health Outcomes and Associations with Self-Reported General Health in Childhood Lymphoma Survivors. Journal of Adolescent and Young Adult Oncology.  ISSN 2156-5333.  6(3), s 470- 476 . doi: 10.1089/jayao.2017.0018
• Johannsdottir, Inga Marie; Karlstad, Øystein; Loge, Jon Håvard; Fosså, Sophie Dorothea; Kiserud, Cecilie E. & Skurtveit, Svetlana (2017). Prescriptions of Antidepressants to Survivors of Cancer in Childhood, Adolescence, and Young Adulthood: A Population-Based Study. Journal of Adolescent and Young Adult Oncology.  ISSN 2156-5333.  6(1), s 120- 126 . doi: 10.1089/jayao.2016.0041
• Lie, Hanne Cathrine; Mellblom, Anneli; Brekke, Mette; Finset, Arnstein; Fosså, Sophie Dorothea; Kiserud, Cecilie E.; Ruud, Ellen & Loge, Jon Håvard (2017). Experiences with late effects-related care and preferences for long-term follow-up care among adult survivors of childhood lymphoma. Supportive Care in Cancer.  ISSN 0941-4355.  25(8), s 2445- 2454 . doi: 10.1007/s00520-017-3651-6
• Nome, Ragnhild Veline; Bjøro, Trine; Paus, Elisabeth; Bjerner, Johan; Fosså, Sophie Dorothea; Steen, Rita; Nustad, Kjell Johannes & Bolstad, Nils (2017). Lowered reference limits for hCG improve follow-up of patients with hCG-producing tumors. Clinical Biochemistry.  ISSN 0009-9120.  52, s 73- 79 . doi: 10.1016/j.clinbiochem.2017.11.016
• Selland, Mette; Smeland, Knut Bjøro; Bjøro, Trine; Falk, Ragnhild Sørum; Fosså, Sophie Dorothea; Gjesdal, Clara Gram; Godang, Kristin; Holte, Harald; Svartberg, Johan; Syversen, Unni; Bollerslev, Jens & Kiserud, Cecilie E. (2017). Bone mineral density is close to normal for age in long-term lymphoma survivors treated with high-dose therapy with autologous stem cell transplantation. Acta Oncologica.  ISSN 0284-186X.  56(4), s 590- 598 . doi: 10.1080/0284186X.2016.1267870
• Skalleberg, Jakob Rasmussen; Popova, Olesya; Fosså, Sophie Dorothea; Småstuen, Milada C; Osnes, Terje; Gundersen, Per Ole Mobråten & Bunne, Bodil Iris Marie (2017). Long-term ototoxicity in women after cisplatin treatment for ovarian germ cell cancer. Gynecologic Oncology.  ISSN 0090-8258.  145(1), s 148- 153 . doi: 10.1016/j.ygyno.2017.02.006
• Van Leeuwen, Marieke; Kieffer, Jacobien M; Efficace, Fabio; Fosså, Sophie Dorothea; Bolla, Michel; Collette, Laurence; Colombel, Marc; De Giorgi, Ugo; Holzner, Bernhard; Van De Poll-Franse, Lonneke V.; Van Poppel, Hendrik; White, Jeff; de Wit, Ronald; Osanto, Susanne; Aaronson, Neil K.; Papiani, Giorgio; Basso, Umberto; Fornarini, Giuseppe; Palmieri, Giovanni; Banna, Giuseppe Luigi & Accettura, Caterina (2017). International evaluation of the psychometrics of health-related quality of life questionnaires for use among long-term survivors of testicular and prostate cancer. Health and Quality of Life Outcomes.  ISSN 1477-7525.  15(1), s 1 . doi: 10.1186/s12955-017-0670-4
• Vatne, Kari; Stensvold, Andreas; Myklebust, Tor Åge; Møller, Bjørn; Svindland, Aud; Kvåle, Rune & Fosså, Sophie Dorothea (2017). Pre- and post-prostatectomy variables associated with pelvic post-operative radiotherapy in prostate cancer patients: a national registry-based study. Acta Oncologica.  ISSN 0284-186X.  56(10), s 1295- 1301 . doi: 10.1080/0284186X.2017.1314006
• Wheeler, Heather E.; Gamazon, Eric R.; Frisina, Robert D.; Perez-Cervantes, Carlos; Charif, Omar El; Mapes, Brandon; Fosså, Sophie Dorothea; Feldman, Darren R.; Hamilton, Robert J; Vaughn, David J.; Beard, Clair J.; Fung, Chunkit; Kollmannsberger, Christian; Kim, Jeri; Mushiroda, Taisei; Kubo, Michiaki; Ardeshir-Rouhani-fard, Shirin; Einhorn, Lawrence H.; Cox, Nancy J; Dolan, M. Eileen & Travis, Lois B. (2017). Variants in WFS1 and other mendelian deafness genes are associated with cisplatin-associated ototoxicity. Clinical Cancer Research.  ISSN 1078-0432.  23(13), s 3325- 3333 . doi: 10.1158/1078-0432.CCR-16-2809
• Nilsen, Tormod Skogstad; Thorsen, Lene; Fosså, Sophie Dorothea; Wiig, Martin; Kirkegaard, Camilla; Skovlund, Eva; Benestad, Haakon Breien & Raastad, Truls (2016). Effects of strength training on muscle cellular outcomes in prostate cancer patients on androgen deprivation therapy. Scandinavian Journal of Medicine & Science in Sports.  ISSN 0905-7188.  26(9), s 1026- 1035 . doi: 10.1111/sms.12543 Show summary

  Androgen deprivation therapy (ADT) improves lifeexpectancy in prostate cancer (PCa) patients, but is asso-ciated with adverse effects on muscle mass. Here, weinvestigated the effects of strength training during ADTon muscle fiber cross-sectional area (CSA) and regulatorsof muscle mass. PCa patients on ADT were randomizedto 16 weeks of strength training (STG) (n = 12) or acontrol group (CG; n = 11). Muscle biopsies wereobtained from m. vastus lateralis and analyzed by immu-nohistochemistry and western blot. Muscle fiber CSAincreased with strength training (898 μm2, P = 0.04), withthe only significant increase observed in type II fibers(1076 μm2, P = 0.03). There was a trend toward a differ-ence in mean change between groups myonuclei number(0.33 nuclei/fiber, P = 0.06), with the only significantincrease observed in type I fibers, which decreased themyonuclear domain size of type I fibers (P = 0.05). Satel-lite cell numbers and the content of androgen receptorand myostatin remained unchanged. Sixteen weeks ofstrength training during ADT increased type II fiber CSAand reduced myonuclear domain in type I fibers in PCapatients. The increased number of satellite cells normallyseen following strength training was not observed.

• Nilsen, Tormod Skogstad; Thorsen, Lene; Kirkegaard, Camilla; Ugelstad, Ingrid; Fosså, Sophie Dorothea & Raastad, Truls (2016). The effect of strength training on muscle cellular stress in prostate cancer patients on ADT. Endocrine Connections.  ISSN 2049-3614.  5(2), s 74- 82 . doi: 10.1530/EC-15-0120 Show summary

  Background: Androgen deprivation therapy (ADT) for prostate cancer (PCa) is associated with several side effects, including loss of muscle mass. Muscle atrophy is associated with reduced mitochondrial function and increased muscle cellular stress that may be counteracted by strength training. Thus, the aim of this study was to investigate the effect of strength training on mitochondrial proteins and indicators of muscle cellular stress in PCa patients on ADT. Methods: Men diagnosed with locally advanced PCa receiving ADT were randomised to a strength training group (STG) (n=16) or a control group (CG) (n=15) for 16 weeks. Muscle biopsies were collected pre- and post-intervention from the vastus lateralis muscle, and analysed for mitochondrial proteins (citrate synthase, cytochrome c oxidase subunit IV (COXIV), HSP60) and indicators of muscle cellular stress (heat shock protein (HSP) 70, alpha B-crystallin, HSP27, free ubiquitin, and total ubiquitinated proteins) using Western blot and ELISA. Results: No significant intervention effects were observed in any of the mitochondrial proteins or indicators of muscle cellular stress. However, within-group analysis revealed that the level of HSP70 was reduced in the STG and a tendency towards a reduction in citrate synthase levels was observed in the CG. Levels of total ubiquitinated proteins were unchanged in both groups. Conclusion: Although reduced HSP70 levels indicated reduced muscle cellular stress in the STG, the lack of an intervention effect precluded any clear conclusions.

• Cameron, Marte; Kersten, Christian; Vistad, Ingvild; van Helvoirt, Rene; Weyde, Kjetil; Undseth, Christine; Mjaaland, Ingvil; Skovlund, Eva; Fosså, Sophie Dorothea & Guren, Marianne (2016). Palliative pelvic radiotherapy for symptomatic rectal cancer–a prospective multicenter study. Acta Oncologica.  ISSN 0284-186X.  55(12), s 1400- 1407 . doi: 10.1080/0284186X.2016.1191666
• Christiansen, Jon Runar; Massey, Richard; Dalen, Håvard; Kanellopoulos, Adriani; Hamre, Hanne Mari; Fosså, Sophie Dorothea; Ruud, Ellen; Kiserud, Cecilie E. & Aakhus, Svend (2016). Utility of Global Longitudinal Strain by Echocardiography to Detect Left Ventricular Dysfunction in Long-Term Adult Survivors of Childhood Lymphoma and Acute Lymphoblastic Leukemia. American Journal of Cardiology.  ISSN 0002-9149.  118(3), s 446- 452 . doi: 10.1016/j.amjcard.2016.05.021 Show summary

  Measuring left ventricular (LV) global longitudinal strain (GLS) is recommended in screening of long-term cancer survivors for cardiotoxicity. However, there are limited data on GLS in this setting, in particular in survivors with apparently normal LV function without risk factors of impaired GLS. In the present study, we measured GLS in 191 adult survivors of childhood lymphoma or acute lymphoblastic leukemia, with normal LV ejection fraction and fractional shortening (FS) and without known hypertension, diabetes mellitus, myocardial infarction, or stroke. We compared GLS in the survivors with 180 controls. Mean GLS was -19.0 ± 2.2% in the survivor group and -21.4 ± 2.0% in the controls (p <0.001). Impaired GLS, defined as mean - 1.96 SDs in the control group, occurred in 53 of 191 survivors (28%). We included survivors with impaired LV ejection fraction and/or FS or traditional risk factors (n = 231 in all) in multiple regression analyses to explore associations with previous cancer treatment. Survivors treated with mediastinal radiotherapy had an odds ratio of impaired GLS of 5.2 (95% confidence interval 2.2 to 12) compared with other survivors. Survivors treated with cumulative anthracycline doses >300 mg/m(2) had an odds ratio of 4.8 (95% confidence interval 1.7 to 14) of impaired GLS. In conclusion, this study demonstrates a high proportion of LV dysfunction assessed by GLS in apparently healthy adult survivors of childhood cancer. Impaired GLS was associated with previous exposure to mediastinal radiotherapy and high doses of anthracyclines. The prognostic role of measuring GLS in this specific patient population should be examined in prospective studies.

• Christiansen, Jon Runar; Massey, Richard; Dalen, Håvard; Kanellopoulos, Adriani; Hamre, Hanne Mari; Ruud, Ellen; Kiserud, Cecilie E.; Fosså, Sophie Dorothea & Aakhus, Svend (2016). Right ventricular function in long-term adult survivors of childhood lymphoma and acute lymphoblastic leukaemia. European Heart Journal-Cardiovascular Imaging.  ISSN 2047-2404.  17(7), s 735- 741 . doi: 10.1093/ehjci/jew018
• Dahl, Alv A; Østby-Deglum, Marie; Oldenburg, Jan; Bremnes, Roy M.; Dahl, Olav; Klepp, Olbjørn; Wist, Erik & Fosså, Sophie Dorothea (2016). Aspects of posttraumatic stress disorder in long-term testicular cancer survivors: cross-sectional and longitudinal findings. Journal of cancer survivorship.  ISSN 1932-2259.  10(5), s 842- 849 . doi: 10.1007/s11764-016-0529-4
• Dahl, Sigrun; Småstuen, Milada; Dahl, Alv A & Fosså, Sophie Dorothea (2016). Work ability in prostate cancer survivors after radical prostatectomy. Scandinavian Journal of Urology.  ISSN 2168-1805.  50(2), s 116- 122 . doi: 10.3109/21681805.2015.1100674
• Fosså, Sophie Dorothea; Bengtsson, Thomas; Borre, Michael; Ahlgren, Göran; Rannikko, Antti & Dahl, Alv A (2016). Reduction of quality of life in prostate cancer patients: experience among 6200 men in the Nordic countries. Scandinavian Journal of Urology.  ISSN 2168-1805.  50(5), s 330- 337 . doi: 10.1080/21681805.2016.1201859
• Fosså, Sophie Dorothea; Storås, Anne Marie Holck; Steinsvik, Eivind Andreas Svaboe; Myklebust, Tor Åge; Eri, Lars Magne; Loge, Jon Håvard & Dahl, Alv A (2016). Psychometric testing of the Norwegian version of the Expanded Prostate Cancer Index Composite 26-item version (EPIC-26). Scandinavian Journal of Urology.  ISSN 2168-1805.  50(4), s 280- 285 . doi: 10.3109/21681805.2016.1163617
• Fosså, Sophie Dorothea; Wiklund, Fredrik; Klepp, Olbjørn; Angelsen, Anders; Solberg, Arne; Damber, Jan-Erik; Hoyer, Morten & Widmark, Anders (2016). Ten- and 15-yr prostate cancer-specific mortality in patients with nonmetastatic locally advanced or aggressive intermediate prostate cancer, randomized to lifelong endocrine treatment alone or combined with radiotherapy: final results of The Scandinavian Prostate Cancer Group-7. European Urology.  ISSN 0302-2838.  70(4), s 684- 691 . doi: 10.1016/j.eururo.2016.03.021
• Frisina, Robert D.; Wheeler, Heather E.; Fosså, Sophie Dorothea; Kerns, Sarah L.; Fung, Chunkit; Sesso, Howard D.; Monahan, Patrick O.; Feldman, Darren R.; Hamilton, Robert; Vaughn, David J.; Beard, Clair J.; Budnick, Amy; Johnson, Eileen M.; Ardeshir-Rouhani-fard, Shirin; Einhorn, Lawrence H.; Lipshultz, Steven E.; Dolan, M. Eileen & Travis, Lois B. (2016). Comprehensive audiometric analysis of hearing impairment and tinnitus after cisplatin-based chemotherapy in survivors of adult-onset cancer. Journal of Clinical Oncology.  ISSN 0732-183X.  34(23), s 2712- 2720 . doi: 10.1200/JCO.2016.66.8822
• Hauptmann, Michael; Johannessen, Tom Børge; Gilbert, Ethel S.; Stovall, Marilyn; van Leeuwen, Flora E.; Rajaraman, Preetha; Smith, Susan A.; Weathers, Rita E.; Aleman, Berthe M.P.; Andersson, Michael; Curtis, Rochelle E.; Dores, Graça M.; Fraumeni, Joseph F.; Hall, Per; Holowaty, Eric J.; Joensuu, Heikki; Kaijser, Magnus; Kleinerman, Ruth A.; Langmark, Frøydis Tonning; Lynch, Charles F.; Pukkala, Eero; Storm, Hans H.; Vaalavirta, Leila; van den Belt-Dusebout, Alexandra W.; Morton, Lindsay M.; Fosså, Sophie Dorothea & Travis, Lois B. (2016). Increased pancreatic cancer risk following radiotherapy for testicular cancer. British Journal of Cancer.  ISSN 0007-0920.  115(7), s 901- 908 . doi: 10.1038/bjc.2016.272
• Hjelle, Line Veronika; Bremnes, Roy M.; Gundersen, Per Ole Mobråten; Sprauten, Mette; Brydøy, Marianne; Tandstad, Torgrim; Wilsgaard, Tom; Fosså, Sophie Dorothea; Oldenburg, Jan & Haugnes, Hege Sagstuen (2016). Associations between long-term serum platinum and neurotoxicity and ototoxicity, endocrine gonadal function, and cardiovascular disease in testicular cancer survivors. Urologic Oncology.  ISSN 1078-1439.  34(487), s e13- e20 . doi: 10.1016/j.urolonc.2016.06.012
• Jeppesen, Elisabeth; Bjelland, Ingvar; Fosså, Sophie Dorothea; Loge, Jon Håvard & Dahl, Alv A (2016). Health-related quality of life in teenagers with a parent with cancer. European Journal of Oncology Nursing.  ISSN 1462-3889.  22, s 46- 53 . doi: 10.1016/j.ejon.2016.03.004
• Kvammen, Øivind; Myklebust, Tor Åge; Solberg, Arne; Møller, Bjørn; Klepp, Olbjørn; Fosså, Sophie Dorothea & Tandstad, Torgrim (2016). Long-term relative survival after diagnosis of testicular germ cell tumor. Cancer Epidemiology, Biomarkers and Prevention.  ISSN 1055-9965.  25(5), s 773- 779 . doi: 10.1158/1055-9965.EPI-15-1153
• Paur, Ingvild; Lilleby, Wolfgang; Bøhn, Siv Kjølsrud; Hulander, Erik; Klein, Willibrord; Vlatkovic, Ljiljana; Axcrona, Karol; Bolstad, Nils; Bjøro, Trine; Laake, Petter; Tasken, Kristin Austlid; Svindland, Aud; Eri, Lars Magne; Brennhovd, Bjørn; Carlsen, Monica Hauger; Fosså, Sophie Dorothea; Smeland, Sigbjørn; Karlsen, Anette Solli & Blomhoff, Rune (2016). Tomato-based randomized controlled trial in prostate cancer patients: Effect on PSA. Clinical Nutrition.  ISSN 0261-5614.  36(3), s 672- 679 . doi: 10.1016/j.clnu.2016.06.014 Full text in Research Archive.
• Storås, Anne Marie Holck; Sanda, Martin G.; Boronat, Olatz Garin; Chang, Peter; Patil, Dattatraya; Crociani, Catrina; Suarez, Jose Francisco; Småstuen, Milada C; Loge, Jon Håvard & Fosså, Sophie Dorothea (2016). Erectile Dysfunction and Sexual Problems Two to Three Years after Prostatectomy among American, Norwegian, and Spanish Patients. Clinical Genitourinary Cancer.  ISSN 1558-7673.  14(3), s e265- e273 . doi: 10.1016/j.clgc.2015.10.009
• Gjerset, Gunhild Maria; Loge, Jon Håvard; Gudbergsson, Sævar Berg; Bye, Asta; Fosså, Sophie Dorothea; Oldervoll, Line Merethe; Kiserud, Cecilie E.; Demark-Wahnefried, Wendy & Thorsen, Lene (2015). Lifestyles of cancer survivors attending an inpatient educational program—a cross-sectional study. Supportive Care in Cancer.  ISSN 0941-4355.  24, s 1527- 1536 . doi: 10.1007/s00520-015-2936-x

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• Agrawal, Vaibhav; Dinh, Paul C.; Fung, Chunkit; Monahan, Patrick; Althouse, Sandra; Norton, Kelli; Cary, Clint; Einhorn, Lawrence H.; Fosså, Sophie Dorothea; Adra, Nabil & Travis, Lois B. (2020). Adverse health outcomes among US testicular cancer survivors after cisplatin-based chemotherapy vs surgical management. JNCI Cancer Spectrum.  ISSN 2515-5091.  4:pkz079(2), s 1- 9 . doi: 10.1093/JNCICS/PKZ079
• Aas, Kirsti; Fosså, Sophie Dorothea; Kvåle, Rune; Møller, Bjørn; Myklebust, Tor Åge; Vlatkovic, Ljiljana; Müller, Stig & Berge, Viktor (2018). Increasing Time from Diagnosis to Radical Prostatectomy (RP-interval) is Not Associated with Adverse Oncological Outcomes: Implications for cancer patient pathways (CPPs). European Urology. Supplement.  ISSN 1569-9056.  17(14), s e2825- e2827 . doi: 10.1016/S1569-9056(18)33709-6
• Bucher-Johannessen, Cecilie; Page, Christian M.; Haugen, Trine B.; Fosså, Sophie Dorothea; Haugnes, Hege Sagstuen; Grotmol, Tom & Rounge, Trine Ballestad (2018). Epigenetic changes in testicular cancer survivors treated with cisplatin.
• Fosså, Sophie Dorothea (2017). Re: Behandling eller aktiv monitorering ved prostatakreft?. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  137(4), s 259- 260 . doi: 10.4045/tidsskr.17.0046
• Holm, Henriette Veiby; Dahl, Alv A; Klepp, Olbjørn & Fosså, Sophie Dorothea (2017). H.V. Holm og medarbeidere svarer :. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  137(14/15), s 976 . doi: 10.4045/tidsskr.17.0579
• Jacobsen, Ellisiv Lærum; Bye, Asta; Aass, Nina Kathrine; Fosså, Sophie Dorothea; Grotmol, Kjersti Støen; Kaasa, Stein; Loge, Jon Håvard; Moum, Torbjørn Åge & Hjermstad, Marianne Jensen (2017). Correction to: Norwegian reference values for the Short-Form Health Survey 36: development over time. Quality of Life Research.  ISSN 0962-9343.  s 1- 3 . doi: 10.1007/s11136-017-1708-0 Full text in Research Archive.
• Torstveit, Ann Helen; Dahl, Alv A; Fosså, Sophie Dorothea & Utne, Inger (2017). Chronic Fatigue in Testicular Cancer Survivors.
• Fung, Chunkit; Fosså, Sophie Dorothea; Milano, Michael T.; Sahasrabudhe, Deepak M.; Peterson, Derick R. & Travis, Lois B. (2016). Reply to S. Alanee et al. Journal of Clinical Oncology.  ISSN 0732-183X.  34(11), s 1285- 1286 . doi: 10.1200/JCO.2015.65.7015

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