Applied neurophysiology

We aim at taking the lead within method development and application of new methods in clinical neurophysiology.

We are currently involved in both basic research, clinical trials and innovation projects at the Departments of Neurology and Research and Innovation, both in the Neuroscience Clinic.

Projects

• The VIKING project
  The worlds largest database for clinical neurophysiological studies. And a study of the trust to AI- decision support systems among patients and health care professionals
• The ENTRAPME project
  Improved diagnostics for nerve entrapments using machine learning
• The DIGMINE project
  Digital gold mining in historical neurophysiological data for more precise diagnostics
• Neurological home hospital
  An innovation study
• Can people with Charcot-Marie-Tooth Disease improve their balance with added haptic input? [CIBAHI]
  Investigating the role of haptic input on improving balance in people with Charcot Marie Tooth (CMT) disease
• The GeNeup study
  Exploring the genetics of neuropathic pain
• Motor neurons - can they be counted?
  Study of new methods for diagnostics and follow-up of neuromuscular disease
• Tak-861
  Clinical studies of treatment of narcolepsy
• Wearable Electrophysiology Mobility Solutions in Parkinson’s Disease (WEBSPD) 
  Innovation project developing wearable electrophysiology solutions for improving walking and balance in people with Parkinson’s Disease

Cooperation

This group has close collaboration with research groups in Norway and abroad.

National

• Stavanger University Hospital; Marie Bu Kvaløy
• Haukeland University Hospital, Bergen; Tom Eichele
• NTNU and St. Olavs University Hospital, Trondheim; Petter Moe Omland
• Universitety hospital of North-Norway; Sissel Løseth
• Diakonhjemmet Hospital; Hilde Berner Hammer and Ulf Sundin
• National Institute of Occupational Health; STAMI; Dagfinn Matre
• Helse Førde HF; Kristoffer Noszka
• Helse Fonna, Haugesund; Kirsten Solstrand
• Vestfold Hospital Trust, Tønsberg; Anders Horsdal
• Innlandet Hospital Trust; An-Magritt Dimmen
• Hospital of Southern Norway, Kristiansand; Håvard Larsen
• Møre & Romsdal Hospital Trust, Ålesund; Janne Marit Ertresvåg
• Møre & Romsdal Hospital Trust, Molde; Audun Olav Dahlberg
• Nord-Trøndelag Hospital Trust; Anna Grav
• Nordland Hospital Trust, Bodø; Diana Hristova
• OsloMet; Anis Yazidi
• University of South-Eastern Norway; Mohsen Toorani
• The Norwegian Centre for E-health Research; Gro-Hilde Severinsen
• Østfold University College and Norwegian Council for Digital Ethics; Leonora Onarheim Bergsjø
• Oslo Centre for Biostatistics & Epidemiology (OCBE); Andrew Reiner

International

• University of Oxford, UK; David Bennett
• Aarhus Universitetshospital, Denmark; Hatice Tankisi
• David Geffen School of Medicine at UCLA – Los Angeles, USA; Joe Jabre
• Leiden University Medical Center, Netherlands; Martijn Tannemaat
• Uppsala University Hospital, Sweden; Anna Punga

Publications

Selected publications

• Åkerlund M, Baskozos G, Li W, Themistocleous AC, Pascal MMV, Rayner NW, Attal N, Baron R, Baudic S, Bennedsgaard K, Bouhassira D, Comini M, Crombez G, Faber CG, Finnerup NB, Gierthmühlen J, Granovsky Y, Gylfadottir SS, Hébert HL, Jensen TS, John J, Kemp HI, Lauria G, Laycock H, Meng W, Nilsen KB, Palmer C, Rice ASC, Serra J, Smith BH, Tesfaye S, Topaz LS, Veluchamy A, Vollert J, Yarnitsky D, van Zuydam N, Zwart JA, McCarthy MI, Lyssenko V, Bennett DL. "Genetic associations of neuropathic pain and sensory profile in a deeply phenotyped neuropathy cohort"
  Pain. 2024 Oct 29. doi: 10.1097/j.pain.0000000000003463. Epub ahead of print.

  PMID: 39471050.

• Ulvin LB, Nilsen KB, Taubøll E, Etholm L, Heuser K.
  "Sensitivity and specificity of the Salzburg EEG criteria for nonconvulsive status epilepticus"
  Ann Clin Transl Neurol. 2024 Oct;11(10):2685-2695. doi: 10.1002/acn3.52184. Epub 2024 Aug 26. PMID: 39186316; PMCID: PMC11514898.
• Porcheret K, Hopstock LA, Nilsen KB.
  "Prevalence of insomnia in a general adult population cohort using different diagnostic criteria: The seventh survey of the Tromsø study 2015-2016"
  Sleep Med. 2024 Jul;119:289-295. doi: 10.1016/j.sleep.2024.05.002. Epub 2024 May 3. PMID: 38718598.
• Dunker Ø, Uglem M, Bu Kvaløy M, Løseth S, Hjelland IE, Allen SM, Dehli Vigeland M, Kleggetveit IP, Sand T, Nilsen KB (2023);
  "Diagnostic accuracy of the 5.07 monofilament test for diabetes polyneuropathy: influence of age, sex, neuropathic pain and neuropathy severity"
  BMJ Open Diabetes Res Care, 11 (6)
  DOI 10.1136/bmjdrc-2023-003545, PubMed 37989346
• Sørensen DM, Bostock H, Abrahao A, Alaamel A, Alaydin HC, Ballegaard M, Boran E, Cengiz B, de Carvalho M, Dunker Ø, Fuglsang-Frederiksen A, Graffe CC, Jones KE, Kallio M, Kalra S, Krarup C, Krøigård T, Liguori R, Lupescu T, Maitland S, Matamala JM, Moldovan M, Moreno-Roco J, Nilsen KB, Phung L et al. (2023); "Estimating motor unit numbers from a CMAP scan: Repeatability study on three muscles at 15 centres"
  Clin Neurophysiol, 151, 92-99
  DOI 10.1016/j.clinph.2023.04.008, PubMed 37236129
• Tveit J, Aurlien H, Plis S, Calhoun VD, Tatum WO, Schomer DL, Arntsen V, Cox F, Fahoum F, Gallentine WB, Gardella E, Hahn CD, Husain AM, Kessler S, Kural MA, Nascimento FA, Tankisi H, Ulvin LB, Wennberg R, Beniczky S.;
  "Automated Interpretation of Clinical Electroencephalograms Using Artificial Intelligence"
  JAMA Neurol. 2023 Aug 1;80(8):805-812.
  DOI: 10.1001/jamaneurol.2023.1645.