In MS, the body's immune system attacks the myelin, the protective layer surrounding nerve fibers.

In Norway, more than 14,000 people live with MS, and approximately 500 new individuals are diagnosed each year.

Our work helps deepen the understanding of MS and forms a foundation for better therapeutic options, with the ultimate goal of improving the quality of life for people living with MS.

You can contact us here: msforskning@medisin.uio.no

For more information about our research activity, please visit the links to our four research groups:

Projects

Our groups perform various types of translational studies of MS. Here is a selection

  • BOTV-MS: Large epidemiological study ongoing for several years
  • AGE-MS: Study investigating aging in MS
  • NOR-MS & IMPROVE MS: National randomized controlled trials evaluating the effects of cladribine and rituximab
  • EBV-MS: Major EU-funded project under NeuroSysMed
  • MultipleMS / WISDOM: EU project coordinated by Karolinska Institute
  • IMSGC: International MS Genetics Consortium
  • NevroVAX: National study of vaccine-induced immune responses in MS
  • OVERLORD MS: National RCT comparing ocrelizumab and rituximab
  • HMAS for MS at OUH: Prospective study of hematopoietic stem cell treatment in MS at OUH
  • NORSEMAN MS: National RCT studying nicotinamide adenine dinucleotide (NAD) in progressive MS
  • MPROVIZE MS: Radiological study of chronic active lesions in MS
  • Back to the B-ginning: Project studying the role of B cells in MS
  • epiNOR-MS: Project exploring epigenetic factors in MS
  • MAGNIMS: We are associate members of this international MRI consortium for MS research, together with San Raffaele Hospital, Milan
  • AIMS: Artificial Intelligence in MS: Project using modern AI methods to increase the precision of the MRI assessments in MS

Cooperation

Our research group has collaboration with several national and international institutions.

National

  • Department of Medical Genetics, OUH
  • Department of Psychology, UiO
  • Institute of Basic Medical Sciences, UiO
  • Department of Ophthalmology, Institute of Clinical Medicine, UiO
  • NORMENT, UiO
  • Hakadal MS Center
  • SINTEF
  • Norwegian MS Registry and Biobank
  • Mathias Toft, Department of Neurology, OUH and UiO
  • John-Anker Zwart, Department of Neurology, OUH and UiO
  • Allicia Llorente, Institute for Cancer Research, OUH
  • Hans-Christian Aas, Flow Cytometry Core Facility, OUH
  • Kaja Selmer, Department of Neurology, OUH
  • Cecilia Smith Simonsen, Department of Neurology, OUH and Vestre Viken, Drammen Hospital
  • Mona Beyer, Department of Radiology and Nuclear Medicine, OUH
  • Randi Eikeland, Sørlandet Hospital
  • Åslaug Lorentzen, Sørlandet Hospital
  • Øivind Torkildsen, Kjell-Morten Myhr, Britt Ellen Rød, Haukeland University Hospital and University of Bergen
  • Trygve Holmøy, Akershus University Hospital and UiO
  • Fridtjof Lund-Johansen, Ludvig Munthe, Jon Torgils Waage, Institute of Clinical Medicine, University of Oslo and Department of Immunology and Transfusion Medicine, OUH
  • Siri Mjåland, Asia Wolf, Norwegian Institute of Public Health
  • Trygve Bergeland, Kappa Biosciences
  • Johanna Gehin, David Warre, Department of Medical Biochemistry, OUH
  • Andreas Lossius, Rune A. Høglund, Institute of Basic Medical Sciences, University of Oslo and Department of Neurology, Akershus University Hospital
  • Stig Wergeland, Jan Aarseth, Haukeland University Hospital and Norwegian MS Registry and Biobank
  • Frode Tuvnes, Ellen Regine Olsrud, Translational MRI Imaging Core Facility, OUH
  • Ingvild Leknes, Åse Mygland, Dept of Neurology, Sørlandet Hospital
  • Atle Bjørnerud, Jon André Ottersen, CRAI, OUH
  • Lars Tjelta Westlye, Ole A. Andreassen, Esten Leonardsen, Nils Inge Landrø, Dag Alnæs, Ivan Maximov, Tobias Kaufmann, Department of Psychology, UiO
  • Per Kristian Eide, Geir Ringstad, Erik Melin, K.G. Jebsen Centre for Brain Fluid Research, OUH and UiO
  • Peyman Mirtaheri, Dept of Mechanical, Electronics and Chemical Engineering, OsloMet
  • Heidi Ormstad, University of South-Eastern Norway and OsloMet
  • Frederic Meyer, Ragnhild Halvorsrud, Trine Seeberg, SINTEF

International

  • Nordic Multiple Sclerosis Genetics Network
  • University of Cambridge MS Genetics Group
  • International Multiple Sclerosis Genetics Consortium (IMSGC)
  • Pablo Villoslada, Hospital Clinic of Barcelona, Spain
  • Stephen Sawcer, University of Cambridge, UK
  • Ingrid Kockum, Maja Jagodic, Tobias Granberg, Fredrik Piehl, Karolinska Institute, Sweden
  • Dr. Vicki Maltby, University of Newcastle, Australia
  • Kaj Blennow, Henrik Zetterberg, Sahlgrenska University Hospital, Gothenburg, Sweden
  • Hanneke Hulst, Leiden University, Netherlands
  • Menno Schoonheim, Amsterdam UMC, Netherlands
  • Sergio E. Baranzini, University of California, San Francisco, USA
  • Nordic MS Genetics Consortium (Hillert, Olsson, Kockum, Oturai, Sørensen, Saarela)
  • Paul Lillrank, Aalto University, Finland