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Rehabilitation after trauma

The goal of this research group is to generate knowledge of the mechanisms and consequences of trauma, patient care, trends and challenges in treatment and rehabilitation, including the patient's healthcare needs, with the main focus being on multiple trauma, traumatic brain injuries (TBIs) and spontaneous subarachnoid hemorrhage.

The research conducted by this group is multidisciplinary and collaborative, where collaboration between genetics, intensive medicine, neurosurgery, neuroradiology, neuropsychology and rehabilitation has been established over the last 10 years.

Main aims

  • To better understand the mechanisms, course and consequences of TBI and multiple traumas by using translational research strategy
  • To develop and build evidence-based efficient protocols for the rehabilitation implementation
  • To strengthen existing and initiate new national and international research collaborations on trauma/TBI research

Specific aims

We intend to generate research-based knowledge on:

  • The biomarkers of TBI and the severity of injuries including morphological changes in the brain
  • Short-term and long-term outcomes and recovery process (physical, cognitive and psychosocial functioning, return to work, and health related quality of life)
  • The organization of patient care, rehabilitation trajectories and cost-effect of rehabilitation interventions
  • Patients’ needs for health care services


This broad range of areas requires close collaboration with research groups in Norway and abroad.


  • Oslo Traumatic Brain Injury Outcome and Rehabilitation Research Network (OBIOR- research network)
  • Sunnaas Rehabilitation Hospital HF
  • University Hospital of North Norway HF
  • St Olavs hospital HF
  • The universities of Oslo, Tromsø, Bergen and Trondheim
  • OsloMet
  • NAV


  • Karolinska institute, Uppsala, Umeå and Salgrenska University Hospitals, Sweden
  • Copenhagen University Hospital and Hammel Rehabilitation and Research Centre, Denmark
  • Virginia Commonwealth University, Richmond, US
  • BioCruces Health Research Institute, Spain
  • University of California, San Diego, CA, USA
  • University of Gottingen, Germany
  • University of Salamanca, Spain
  • Hannover Medical School, Germany
  • CENTER-TBI collaborators across the European hospitals/universities

Selected publications

  • Andelic N, Røe C, Brunborg C, Zeldovich M, Løvstad M, Løke D, Borgen IM, Voormolen DC, Howe EI, Forslund MV, Dahl HM, von Steinbuechel N; CENTER-TBI participants investigators. “Frequency of fatigue and its changes in the first 6 months after traumatic brain injury: results from the CENTER-TBI study” J Neurol. Epub 2020 Jul 16. doi: 10.1007/s00415-020-10022-2
  • Sveen U, Guldager R, Soberg HL, Andreassen TA, Egerod I, Poulsen I. “Rehabilitation interventions after traumatic brain injury: a scoping review” Disabil Rehabil. 2020 Jun 13:1-8. doi: 10.1080/09638288.2020.1773940
  • Rasmussen MS, Arango-Lasprilla JC, Andelic N, Nordenmark TH, Soberg HL. "Mental Health and Family Functioning in Patients and Their Family Members after Traumatic Brain Injury: A Cross-Sectional Study" Brain Sci. 2020 Sep 25;10(10):670. doi: 10.3390/brainsci10100670
  • Howe EI, Fure SCR, Løvstad M, Enehaug H, Sagstad K, Hellstrøm T, Brunborg C, Røe C, Nordenmark TH, Søberg HL, Twamley E, Lu J, Andelic N. “Effectiveness of Combining Compensatory Cognitive Training and Vocational Intervention vs. Treatment as Usual on Return to Work Following Mild-to-Moderate Traumatic Brain Injury: Interim Analysis at 3 and 6 Month Follow-Up” Front Neurol. 2020 Nov 10;11:561400. doi: 10.3389/fneur.2020.561400
  • Gormley M, Devanaboyina M, Andelic N, Røe C, Seel RT, Lu J Long-term employment outcomes following moderate to severe traumatic brain injury: a systematic review and meta-analysis. Brain Inj, 2019. 33 (13-14), 1567-1580
  • Holthe OO, Hellstrom T, Andelic N, Server A, Sigurdardottir S Improvement and Prediction of Memory and Executive Functions in Patients Admitted to a Neurosurgery Service With Complicated and Uncomplicated Mild Traumatic Brain Injury. J Head Trauma Rehabil, 2019. 34 (5), E45-E56
  • Røe C, Tverdal C, Howe EI, Tenovuo O, Azouvi P, Andelic N Randomized Controlled Trials of Rehabilitation Services in the Post-acute Phase of Moderate and Severe Traumatic Brain Injury - A Systematic Review. Front Neurol, 2019. 10, 557
  • Maas AIR, Menon DK, Adelson PD, Andelic N et al (InTBIR Participants and Investigators). Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research. Lancet Neurol. 2017 Nov 6. pii: S1474-4422(17)30371-X
  • Soberg HL, Roe C, Brunborg C, von Steinbüchel N, Andelic N. The Norwegian version of the QOLIBRI - a study of metric properties based on a 12 month follow-up of persons with traumatic brain injury. Health Qual Life Outcomes. 2017 Jan 19;15(1)
  • Røe C, Skandsen T, Manskow U, Ader T, Anke A. Mortality and One-Year Functional Outcome in Elderly and Very Old Patients with Severe Traumatic Brain Injuries: Observed and Predicted. Behav Neurol. 2015; 845491
  • Soberg HL, Bautz-Holter E, Finset A, Roise O, Andelic N. Physical and mental health 10 years after multiple trauma: A prospective cohort study. J Trauma Acute Care Surg. 2015 Mar;78(3):628-33
  • Andelic N, Ye J, Tornas S, Roe C, Lu J, Bautz-Holter E, Moger T, Sigurdardottir S, Schanke AK, Aas E. Cost-effectiveness analysis of an early-initiated, continuous chain of rehabilitation after severe traumatic brain injury. J Neurotrauma 2014; 15; 31:1313-20
Tags: USA, Nordic
Published Mar. 10, 2015 11:25 AM - Last modified Sep. 20, 2021 3:43 PM


Group leader


  • Nada Hadzic-Andelic
  • Cecilie Røe
  • Erik Bautz-Holter
  • Unni Sveen
  • Helene L. Søberg
  • Tonje Haug Nordenmark
  • Marit V. Forslund
  • Ingerid Kleffelgaard
  • Tanja Karic
  • Torgeir Hellstrøm
  • Mari S. Rasmussen
  • Elin Western
  • Emilie I. Howe
  • Silje Fure
  • Ida M. Borgen Henriksen
  • Håkon Moksnes
  • Line Preede
  • Cathrine Buaas Tverdal
Detailed list of participants