Virology research group
The group is a collaboration between clinical and laboratory research experts of human immunodeficiency virus type 1 (HIV) and cytomegalovirus (CMV).
About the group
The group consists of clinicians and scientists that are interested in the molecular and clinical aspects of chronic virus infections. We are using human cytomegalovirus (CMV) and immune deficiency virus type-1 (HIV) as model systems.
Our main focus is how these viruses affect their host cells with regard to latency, genome stability and their interaction with the immune system.
The group is affiliated to the national reference laboratories for CMV at Rikshospitalet and HIV at Ullevål.
CMV and HIV cause chronic infections in humans. Often the primary infection is asymptomatic but establishes lifelong latency.
Upon certain conditions like immune suppression the virus might reactivate and cause disease.
We study the pathogenesis and immune responses during these viral infections in order to better understand virus-host cell interactions. This may unravel mechanisms of importance for improved treatment strategies and principles.